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Showing 1 - 200 of 3562 Journals sorted alphabetically
16 de Abril     Open Access  
AADE in Practice     Hybrid Journal   (Followers: 4)
ABCS Health Sciences     Open Access   (Followers: 1)
Abia State University Medical Students' Association Journal     Full-text available via subscription  
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ACS Medicinal Chemistry Letters     Full-text available via subscription   (Followers: 39)
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Advances in Virus Research     Full-text available via subscription   (Followers: 5)
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African Health Sciences     Open Access   (Followers: 2)
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African Journal of Clinical and Experimental Microbiology     Open Access   (Followers: 1)
African Journal of Laboratory Medicine     Open Access   (Followers: 2)
African Journal of Medical and Health Sciences     Open Access   (Followers: 1)
African Journal of Trauma     Open Access  
Afrimedic Journal     Open Access   (Followers: 2)
Aggiornamenti CIO     Hybrid Journal   (Followers: 1)
AIDS Research and Human Retroviruses     Hybrid Journal   (Followers: 8)
AJOB Primary Research     Partially Free   (Followers: 3)
Aktuelle Ernährungsmedizin     Hybrid Journal   (Followers: 4)
Al-Azhar Assiut Medical Journal     Open Access  
Alexandria Journal of Medicine     Open Access  
Allgemeine Homöopathische Zeitung     Hybrid Journal   (Followers: 2)
Alpha Omegan     Full-text available via subscription  
ALTEX : Alternatives to Animal Experimentation     Open Access   (Followers: 3)
American Journal of Biomedical Engineering     Open Access   (Followers: 11)
American Journal of Biomedical Research     Open Access   (Followers: 2)
American Journal of Biomedicine     Full-text available via subscription   (Followers: 6)
American Journal of Chinese Medicine, The     Hybrid Journal   (Followers: 5)
American Journal of Clinical Medicine Research     Open Access   (Followers: 6)
American Journal of Family Therapy     Hybrid Journal   (Followers: 11)
American Journal of Law & Medicine     Full-text available via subscription   (Followers: 13)
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American Journal of Medical Case Reports     Open Access   (Followers: 1)
American Journal of Medical Sciences and Medicine     Open Access   (Followers: 1)
American Journal of Medicine     Hybrid Journal   (Followers: 45)
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American Journal of Medicine Studies     Open Access  
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American Journal of the Medical Sciences     Hybrid Journal   (Followers: 12)
American Journal on Addictions     Hybrid Journal   (Followers: 9)
American Medical Journal     Open Access   (Followers: 4)
American medical news     Free   (Followers: 3)
American Medical Writers Association Journal     Full-text available via subscription   (Followers: 2)
Amyloid: The Journal of Protein Folding Disorders     Hybrid Journal   (Followers: 4)
Anales de la Facultad de Medicina     Open Access  
Anales de la Facultad de Medicina, Universidad de la República, Uruguay     Open Access  
Anales del Sistema Sanitario de Navarra     Open Access   (Followers: 1)
Analgesia & Resuscitation : Current Research     Hybrid Journal   (Followers: 2)
Anatomical Science International     Hybrid Journal   (Followers: 2)
Anatomical Sciences Education     Hybrid Journal   (Followers: 1)
Anatomy Research International     Open Access   (Followers: 2)
Angewandte Schmerztherapie und Palliativmedizin     Hybrid Journal  
Angiogenesis     Hybrid Journal   (Followers: 3)
Annales de Pathologie     Full-text available via subscription  
Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale     Full-text available via subscription   (Followers: 3)
Annals of African Medicine     Open Access   (Followers: 1)
Annals of Anatomy - Anatomischer Anzeiger     Hybrid Journal   (Followers: 2)
Annals of Bioanthropology     Open Access   (Followers: 3)
Annals of Biomedical Engineering     Hybrid Journal   (Followers: 18)
Annals of Biomedical Sciences     Full-text available via subscription   (Followers: 3)
Annals of Clinical Microbiology and Antimicrobials     Open Access   (Followers: 8)
Annals of Family Medicine     Open Access   (Followers: 13)
Annals of Fundeni Hospital     Open Access   (Followers: 1)
Annals of Ibadan Postgraduate Medicine     Open Access  
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Medicine     Hybrid Journal   (Followers: 11)
Annals of Medicine and Surgery     Open Access   (Followers: 5)
Annals of Microbiology     Hybrid Journal   (Followers: 10)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Saudi Medicine     Open Access  
Annals of the New York Academy of Sciences     Hybrid Journal   (Followers: 5)
Annals of The Royal College of Surgeons of England     Full-text available via subscription   (Followers: 3)
Annual Reports in Medicinal Chemistry     Full-text available via subscription   (Followers: 7)
Annual Reports on NMR Spectroscopy     Full-text available via subscription   (Followers: 4)
Annual Review of Medicine     Full-text available via subscription   (Followers: 18)
Anthropological Review     Open Access   (Followers: 24)
Anthropologie et santé     Open Access   (Followers: 5)
Antibiotics     Open Access   (Followers: 9)
Antibodies     Open Access   (Followers: 2)
Antibody Technology Journal     Open Access   (Followers: 1)
Anuradhapura Medical Journal     Open Access  
Anwer Khan Modern Medical College Journal     Open Access   (Followers: 2)
Apmis     Hybrid Journal   (Followers: 1)
Apparence(s)     Open Access   (Followers: 1)
Applied Clinical Informatics     Hybrid Journal   (Followers: 2)
Applied Medical Informatics     Open Access   (Followers: 11)
Arab Journal of Nephrology and Transplantation     Open Access   (Followers: 1)
Arak Medical University Journal     Open Access  
Archive of Clinical Medicine     Open Access   (Followers: 1)
Archive of Community Health     Open Access  
Archives of Biomedical Sciences     Open Access   (Followers: 7)
Archives of Medical and Biomedical Research     Open Access   (Followers: 3)
Archives of Medical Laboratory Sciences     Open Access   (Followers: 1)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Archives of Trauma Research     Open Access   (Followers: 2)
Archivos de Medicina (Manizales)     Open Access  
ArgoSpine News & Journal     Hybrid Journal  
Arquivos Brasileiros de Oftalmologia     Open Access  
Arquivos de Ciências da Saúde     Open Access  
Arquivos de Medicina     Open Access  
ARS Medica Tomitana     Open Access   (Followers: 1)
Art Therapy: Journal of the American Art Therapy Association     Full-text available via subscription   (Followers: 10)
Arterial Hypertension     Open Access  
Artificial Intelligence in Medicine     Hybrid Journal   (Followers: 12)
Artificial Organs     Hybrid Journal   (Followers: 1)
Asia Pacific Family Medicine     Open Access  
Asia Pacific Journal of Clinical Nutrition     Full-text available via subscription   (Followers: 10)
Asia Pacific Journal of Clinical Trials : Nervous System Diseases     Open Access  
Asian Bioethics Review     Full-text available via subscription   (Followers: 1)
Asian Journal of Cell Biology     Open Access   (Followers: 6)
Asian Journal of Health     Open Access   (Followers: 3)
Asian Journal of Medical and Biological Research     Open Access   (Followers: 2)
Asian Journal of Medical and Pharmaceutical Researches     Open Access   (Followers: 1)
Asian Journal of Medical Sciences     Open Access   (Followers: 1)
Asian Journal of Scientific Research     Open Access   (Followers: 1)
Asian Journal of Transfusion Science     Open Access   (Followers: 2)
Asian Medicine     Hybrid Journal   (Followers: 4)
ASPIRATOR : Journal of Vector-borne Disease Studies     Open Access  
Astrocyte     Open Access  
Atención Familiar     Open Access  
Atención Primaria     Open Access   (Followers: 1)
Audiology - Communication Research     Open Access   (Followers: 8)
Auris Nasus Larynx     Full-text available via subscription  
Australasian Medical Journal     Open Access   (Followers: 3)
Australian Coeliac     Full-text available via subscription   (Followers: 2)
Australian Family Physician     Full-text available via subscription   (Followers: 3)
Australian Journal of Medical Science     Full-text available via subscription   (Followers: 1)
Autopsy and Case Reports     Open Access  
Aviation, Space, and Environmental Medicine     Full-text available via subscription   (Followers: 9)
Avicenna     Open Access   (Followers: 2)
Avicenna Journal of Medicine     Open Access   (Followers: 1)
Bangabandhu Sheikh Mujib Medical University Journal     Open Access   (Followers: 1)
Bangladesh Journal of Anatomy     Open Access   (Followers: 1)
Bangladesh Journal of Bioethics     Open Access  
Bangladesh Journal of Medical Biochemistry     Open Access   (Followers: 3)
Bangladesh Journal of Medical Education     Open Access   (Followers: 2)
Bangladesh Journal of Medical Microbiology     Open Access   (Followers: 2)
Bangladesh Journal of Medical Physics     Open Access  
Bangladesh Journal of Medical Science     Open Access  
Bangladesh Journal of Medicine     Open Access   (Followers: 1)
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Bangladesh Journal of Scientific Research     Open Access   (Followers: 1)
Bangladesh Medical Journal     Open Access  
Bangladesh Medical Journal Khulna     Open Access  
Bangladesh Medical Research Council Bulletin     Open Access  
Basal Ganglia     Hybrid Journal  
Basic Sciences of Medicine     Open Access   (Followers: 2)
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BC Medical Journal     Free  
Benha Medical Journal     Open Access  
Bijblijven     Hybrid Journal  
Bijzijn     Hybrid Journal   (Followers: 2)
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Bio-Algorithms and Med-Systems     Hybrid Journal   (Followers: 1)
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Bioengineering & Translational Medicine     Open Access  
Bioethics     Hybrid Journal   (Followers: 14)
Bioethics Research Notes     Full-text available via subscription   (Followers: 14)
Biologics in Therapy     Open Access  
Biology of Sex Differences     Open Access   (Followers: 4)
Biomarker Research     Open Access   (Followers: 2)

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Journal Cover Acta Médica Costarricense
  [2 followers]  Follow
  This is an Open Access Journal Open Access journal
   ISSN (Print) 0001-6002
   Published by SciELO Homepage  [717 journals]
  • La investigación clínica en Costa Rica se encuentra en un punto
           crítico: aplicación actual de la “Ley Reguladora de Investigación

  • (Evidence based medicine: the case of blood pressure targets)

    • Abstract: ResumenEl concepto de “Medicina basada en evidencias”, que ha adquirido mayor trascendencia en el transcurso de los últimos años, se apoya en el postulado de que la enseñanza y la práctica clínica de la medicina, así como la definición de las políticas de salud a nivel poblacional, deben estar respaldadas por evidencias científicas sólidas, que demuestren que existe una adecuada relación entre los beneficios y los potenciales inconvenientes asociados con la implementación práctica de cualquier intervención preventiva, diagnóstica o terapéutica. Lamentablemente, en la realidad muchas de las acciones usuales en la práctica médica no cumplen con esas condiciones, lo que puede resultar en una utilización inapropiada de los recursos disponibles y en la exposición de los pacientes a riesgos innecesarios. La “medicina basada en evidencias” parte de un análisis crítico exhaustivo de los diversos estudios clínicos que hayan evaluado una cuestión específica, con el fin de identificar la evidencia de mayor calidad y solidez científica disponible, y a partir de ahí, realizar una cuantificación que permita establecer si la balanza de los beneficios y de los riesgos justifica su aplicación clínica. Además, es un proceso dinámico, cuyos resultados pueden irse modificando paulatinamente, con el objetivo de mejorar la atención médica, a medida que surgen nuevas evidencias de calidad. El caso de las cifras meta de presión arterial usadas en el tratamiento de la hipertensión arterial, es un tópico que ha sido sometido en años recientes al proceso de análisis de las evidencias; como resultado, han ocurrido cambios e implicaciones a nivel clínico y académico, y sirve de ejemplo para ilustrar el proceso descrito.AbstractThe concept of “Evidence Based Medicine”, which has achieved greater importance during the last years, is based on the idea that teaching and practicing clinical medicine, as well as the definition of health policies at the population level, should be supported by solid scientific evidences showing that there is an adequate relationship between the benefits and potential risks associated with the practical implementation of any preventive, diagnostic, or therapeutic intervention. Unfortunately, many of the usual actions in medical practice do not fulfill those conditions, which may result in inappropriate use of available resources and exposure of patients to unnecessary risks. “Evidence Based Medicine” starts from an exhaustive critical inquiry of the clinical studies that have evaluated a specific issue, in order to identify the available evidence with higher quality and scientific support, and from there to perform a quantitative analysis that allows determining if the benefits/risks balance justifies its clinical application. In addition, it is a dynamic process, whose results can be gradually modified as new quality evidence emerges, with the final objective of improving medical care. The case of blood pressure targets used in the treatment of arterial hypertension is a topic that has been subjected in recent years to the process of analysis of the evidence. As a result, changes and implications have occurred both at clinical and academic levels, and it serves as an example to illustrate the process described above.
  • (Cardiovascular complications in hospitalized patients with
           community-acquired pneumonia: retrospective cohort study)

    • Abstract: ResumenJustificación y objetivo:Algunos estudios han documentado mayor riesgo de eventos cardiovasculares en pacientes con neumonía adquirida en la comunidad. El objetivo del estudio es caracterizar la población de pacientes con diagnóstico de neumonía adquirida en la comunidad e identificar factores relacionados con el desarrollo de complicaciones cardiovasculares y muerte a 30 días.Métodos:se realizó un estudio observacional de cohorte retrospectivo con casos y controles en el Servicio de Medicina Interna en un hospital universitario de nivel terciario, con pacientes con diagnóstico de neumonía adquirida en la comunidad. Se evaluaron variables clínicas y de laboratorio de los pacientes ingresados, así como diagnóstico clínico de arritmia, infarto agudo de miocardio, insuficiencia cardiaca de nuevo, o empeoramiento de cuadro preexistente, edema pulmonar y muerte en los 30 días posteriores al ingreso (casos), o ausencia de estos hallazgos (controles).Resultados:se identificó 35 casos de neumonía adquirida en la comunidad, de los cuales 17 presentaron complicaciones cardiovasculares (48,57%). Los pacientes de mayor edad, de sexo femenino, hipertensos y cardiópatas isquémicos, tuvieron mayor riesgo de eventos cardiovasculares, así como los que presentaron al ingreso mayores valores de presión sistólica, creatin fosfokinasa y nitrógeno ureico. El 22,85% de los pacientes falleció en los siguientes 30 días posteriores al ingreso por neumonía; el riesgo de muerte fue mayor para los pacientes con complicaciones cardiovasculares [Hazard ratio 8,8 (IC95% 1,08-71,66; p=0,03)]. No se encontró asociación entre las diferencias clínicas identificadas y el desenlace fatal. Limitaciones: las variables se tomaron de los expedientes clínicos, dependiendo completamente del criterio de los médicos tratantes para solicitud de exámenes y asignación de variables. Es posible la presencia de factores de confusión debido a covariables no medidas o severidad de la enfermedad.Conclusión:en los pacientes internados con diagnóstico de neumonía adquirida en la comunidad, el desarrollo de complicaciones cardiovasculares se asoció con aumento de mortalidad.AbstractJustification and objectives:Previous studies have demonstrated increased risk of cardiovascular events in patients with community-acquired pneumonia. The objective of this study is to characterize the population of patients diagnosed with community-acquired pneumonia and identify factors associated with the development of cardiovascular complications and 30-day mortality.Methods:A retrospective observational case-control cohort was done, with cases and controls in the department of Internal Medicine at a tertiary level teaching hospital with patients diagnosed with community-acquired pneumonia. Clinical and laboratory variables of patients admitted were evaluated, also the clinical diagnosis of arrhythmia, acute myocardial infarction, heart failure (new or worsening), pulmonary edema and death within 30 days after admission (cases) or absence of these findings (controls).Results:35 cases of community-acquired pneumonia were identified on the first semester of 2015, of which 17 (48.57%) developed cardiovascular complications. Older patients, female sex, hypertension and ischemic heart disease demonstrated higher risk of cardiovascular events, as well as presenting the systolic blood pressure, creatine phosphokinase and urea nitrogen. The 22.85% of patients died within 30 days after being admitted; the risk of death was higher for patients with cardiovascular complications [Hazard ratio 8.8 (95% CI 1.08-71.66; p = 0.03)]. No association between the identified clinical differences and fatal outcome was found. Limitations:The retrospective nature of the study and the variables, which were collected from clinical records, depended entirely on the discretion of the treating physicians to request tests and variable allocation. The presence of confounding is possible due to unmeasured covariates or disease severity.Conclusions:In patients admitted with a diagnosis of community-acquired pneumonia the development of cardiovascular complications was associated with increased mortality.
  • (Management Guidelines of Rheumatoid Arthritis Consensus 2016)

    • Abstract: ResumenLa artritis reumatoide sigue representando un importante factor de deterioro de la salud de las personas que sufren esta condición, a pesar de los avances recientes en su tratamiento. En forma adicional, se reconoce su significativo impacto a nivel social y económico. La Asociación Costarricense de Reumatología publicó en 2010, las primeras guías de manejo de esta enfermedad.En el presente trabajo, este primer documento fue actualizado, mediante la revisión exaustiva de la información científica disponible y relevante a la fecha, con el objetivo de uniformar y optimizar la atención de la artritis reumatoide en Costa Rica. Incluye las recomendaciones de evaluación de los pacientes, su seguimiento y tratamiento. También se revisan las opciones de medicamentos disponibles en el país, es decir, drogas modificadoras de los síntomas y fármacos modificadores de la enfermedad convencionales, además de agentes biológicos y moléculas pequeñas.AbstractRheumatoid arthritis continues to represent an important factor of deterioration in the health of people suffering from this condition despite recent medical advances in their treatment. Additionally, its significant social and economic impact it is recognized. The Costa Rican Association of Rheumatology published in 2010 the first guidelines for the management of this disease. In the present work, this first document is updated, through an exhaustive review of the available and relevant scientific information to date. This review aims to standardize and optimize the care of rheumatoid arthritis in Costa Rica. It includes recommendations for evaluation of patients, follow-up and treatment. There is also a review of drug options available in the country, i.e., symptoms-modifying drugs, conventional disease modifying drugs, as well as biological agents and small molecules.
  • (Penile reconstruction with microsurgery)

    • Abstract: ResumenEl pene tradicionalmente se ha considerado un símbolo de poder, masculinidad y fertilidad, por lo cual toda patología peniana congénita o adquirida, que eventualmente culmine en la amputación parcial o total del falo, constituye un evento catastrófico para cualquier hombre, presentando efectos devastadores, tanto físicos como psicológicos. Los diferentes niveles de amputación peniana en un individuo pueden definir su capacidad de miccionar y de concretar el coito, lo que perjudica directamente su virilidad y desempeño sexual y, por ende, su bienestar psicológico. Todo esto justifica el esfuerzo reconstructivo que se pueda ofrecer con el fin de mejorar la calidad de vida del paciente. El colgajo libre radial de antebrazo se ha considerado por muchos años el estándar de oro en reconstrucción peniana, ya que ha demostrado buenos resultados funcionales y estéticos. Esta técnica microquirúrgica representa un gran avance reconstructivo, lo cual se traduce en un rescate de la autoestima y de la masculinidad del paciente, con mejoría significativa de su calidad de vida. A continuación se presenta el caso clínico de un paciente masculino de 35 años de edad, quien requirió una amputación casi total de pene, secundaria a una quemadura eléctrica severa, y posteriormente fue sometido a la primera reconstrucción peniana microquirúrgica con colgajo libre radial de antebrazo, en Costa Rica.AbstractThe penis has traditionally been considered a symbol of power, masculinity and fertility, so any congenital or acquired penile pathology that eventually culminates in partial or total amputation of the phallus constitutes a catastrophic event for any man, presenting both physical and psychological devastating effects. The different levels of penile amputation in an individual can define their ability to micturate and to concretize sexual intercourse, which directly impairs their virility and sexual performance and thus their psychological well-being. All this finally justifies any reconstructive effort that can be offered in order to improve the patient’s quality of life. The free radial forearm flap has been considered for many years the gold standard in penile reconstruction as it has demonstrated good functional and aesthetic results. This microsurgical technique represents a great reconstructive advance, which results in a rescue of the patient’s self-esteem and masculinity with a significant improvement in his quality of life. The authors present the clinical case of a 35-year-old male patient who required an almost total amputation of the penis, secondary to a severe electrical burn and who subsequently underwent the first microsurgical penile reconstruction with a free radial forearm flap in Costa Rica.
  • (Thrombosis in pediatric patient with osteosarcoma)

    • Abstract: ResumenPaciente masculino de 12 años, con cuadro de 2 meses de evolución de dolor en cadera derecha y claudicación, con circulación colateral abdominal y edema de miembro inferior derecho al examen físico, con radiografías de pelvis que muestran masa en cresta iliaca derecha; ultrasonido de abdomen y miembro inferior derecho (con doppler ) con masa en cresta iliaca derecha asociada a trombo oclusivo total de vena iliaca común derecha, hasta vena cava inferior en su desembocadura en aurícula derecha; además, tomografía de tórax con múltiples vasos de circulación colateral con extenso trombo en la vena cava inferior, que se extiende a la aurícula derecha, cruzando la válvula tricúspide e insinuándose en el ventrículo derecho, con múltiples nódulos pulmonares bilaterales, que por sus características, son altamente sugestivos de lesiones metastásicas, y tomografía de pelvis que muestra extensa lesión infiltrante del hueso iliaco derecho, la cual compromete la totalidad del hueso hasta la altura del techo acetabular. Además, se documenta masa de tejido blando que desplaza músculos adyacentes, estructuras vasculares y vísceras de la pelvis hacia la izquierda, con patrón blástico, con áreas líticas que comprometen el aspecto lateral derecho de S3 y S4, encontrándose también infiltradas por la neoplasia.Debido al patrón de destrucción ósea y aspecto morfológico del trombo, se desaconseja trombectomía, y se realiza biopsia tumoral, con reporte de osteosarcoma; se inicia quimioterapia.AbstractA 12-year-old male patient, with a 2-month history of pain in the right hip and claudication, with collateral abdominal circulation and lower right limb edema on physical examination, with pelvic radiographs showing a right iliac crest mass; ultrasound of abdomen and lower right limb (with Doppler) with right iliac crest mass associated with total occlusive thrombus of right common iliac vein, to inferior vena cava at its right atrial outlet; also chest tomography with multiple collateral circulation vessels with extensive thrombus in the inferior vena cava, extending to the right atrium, crossing the tricuspid valve and insinuating itself in the right ventricle, with multiple bilateral pulmonary nodules that, because of their characteristics are highly suggestive of metastatic lesions, and pelvic tomography which shows extensive infiltrating lesion of the right iliac bone, which compromises the entire bone to the height of the acetabular roof; in addition, a mass of soft tissue is documented that displaces adjacent muscles, vascular structures and viscera of the pelvis to the left, with blastic pattern, with lithic areas that compromise the right lateral aspect of S3 and S4, being also infiltrated by the neoplasia.Due to the bone destruction pattern and the morphological aspect of the thrombus, thrombectomy is advised against and tumor biopsy is performed with osteosarcoma report and chemotherapy is initiated.
  • (Chronic diarrhea by Lamblia intestinalis in an adult)

    • Abstract: ResumenSe presenta un caso de inmunodeficiencia común variable en un paciente masculino, joven con larga historia (9 años) de procesos infecciosos gastrointestinales y respiratorios recurrentes; a pesar de los diferentes esquemas terapéuticos, con evidencia diagnóstica de niveles bajos de inmunoglobulinas de las clases IgG, IgM e IgA; se pretende comparar su evolución a partir de su historia clínica y los resultados de sus exámenes complementarios, con la bibliografía revisada. La inmunodeficiencia común variable explica un déficit primario de IgG (al menos 2 desviaciones estándar por debajo de los valores de referencia para su edad), al menos otra de las Ig (IgA o IgM) y una reducción o ausencia de producción de anticuerpos. Esta entidad se considera poco frecuente en términos de incidencia, aunque cursa muchas veces inadvertida por el predominio de sus efectos. Clínicamente, se manifiesta por la presencia de infecciones recurrentes con preponderancia de las respiratorias y gastrointestinales. Desde el punto de vista etiológico, su génesis es controversial, pero se describen niveles bajos de inmunoglobulinas y una reducción o ausencia de producción de anticuerpos.AbstractWe present a variable common immunodeficiency case in a young male patient with a long history (9 years) of recurrent gastrointestinal and respiratory infectious processes, despite the different therapeutic schemes, with diagnostic evidence of low levels of IgG, IgM And IgA; aiming to make a comparison of its evolution in function of its clinical history and the results of its complementary examinations, with the bibliography reviewed. Variablecommon immunodeficiency explains a primary IgG deficit (at least 2 standard deviations below the reference values for his age) and at least one other Ig (IgA or IgM) and a reduction or absence of antibody production. This entity is considered infrequent in terms of incidence, although it is often inadvertent due to the predominance of its effects. Clinically it is manifested by the presence of recurrent infections with preponderance of the respiratory and gastrointestinal. From an aetiological point of view, its genesis is controversial, but low levels of immunoglobulins and a reduction or absence of antibody production are all described.
  • (Surgical management of cardiac myxoma)

    • Abstract: ResumenSe presenta el caso de una paciente de 32 años, con trastorno psiquiátrico, con historia de un mes de evolución de disnea y tos no productiva, tratada inicialmente como bronconeumonía, con amplia cobertura antibiótica sin mejoría de síntomas; se maneja luego como síndrome de dificultad respiratoria aguda. Debido a franco ataque al estado general y datos incongruentes con historia clínica, se realiza ecocardiograma que incidentalmente reporta mixoma en aurícula izquierda. Los mixomas cardíacos son el tipo más común de tumores primarios benignos cardíacos, una patología poco frecuente y con mortalidad asociada a muerte súbita en un 15%. La mayoría de casos son encuentros incidentales, esporádicos y su etiología no es conocida. Los síntomas pueden asociarse a embolismo del tumor, insuficiencia cardiaca, obstrucción mecánica valvular y síntomas constitucionales varios.AbstractWe present the case of a 32 year old patient known to have a psychiatric disorder, who presented with a history of one month of dyspnoea and nonproductive cough, which was treated initially as bronchopneumonia, with wide spectrum antibiotics without clinical improvement. Later is treated as an acute pulmonary distress syndrome, but because of poor general condition and incongruent data in the clinical history an echocardiogram was performed in the Emergency Room that incidentally founds a myxoma in the left atrium. Cardiac myxomas are the most common primary heart benign tumors, and have a mortality rate associated with sudden death of 15%. In the majority of the cases the diagnosis is incidental, sporadic and the etiology is unknown.The symptoms may be associated with tumor embolism, heart failure, valvular disease and nonspecific symptoms.
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
Tel: +00 44 (0)131 4513762
Fax: +00 44 (0)131 4513327
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