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  Subjects -> MEDICAL SCIENCES (Total: 7272 journals)
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    - RHEUMATOLOGY (63 journals)
    - SPORTS MEDICINE (68 journals)
    - SURGERY (349 journals)
    - UROLOGY, NEPHROLOGY AND ANDROLOGY (131 journals)

MEDICAL SCIENCES (1808 journals)                  1 2 3 4 5 6 7 8 | Last

Showing 1 - 200 of 3562 Journals sorted alphabetically
16 de Abril     Open Access  
AADE in Practice     Hybrid Journal   (Followers: 4)
ABCS Health Sciences     Open Access   (Followers: 1)
Abia State University Medical Students' Association Journal     Full-text available via subscription  
ACIMED     Open Access   (Followers: 1)
ACS Medicinal Chemistry Letters     Full-text available via subscription   (Followers: 39)
Acta Bio Medica     Full-text available via subscription   (Followers: 2)
Acta Bioethica     Open Access   (Followers: 1)
Acta Bioquimica Clinica Latinoamericana     Open Access   (Followers: 1)
Acta Facultatis Medicae Naissensis     Open Access  
Acta Informatica Medica     Open Access   (Followers: 1)
Acta Medica Bulgarica     Open Access  
Acta Medica Colombiana     Open Access   (Followers: 1)
Acta Médica Costarricense     Open Access   (Followers: 2)
Acta Medica Indonesiana     Open Access  
Acta medica Lituanica     Open Access  
Acta Medica Marisiensis     Open Access  
Acta Medica Martiniana     Open Access  
Acta Medica Nagasakiensia     Open Access  
Acta Medica Peruana     Open Access   (Followers: 2)
Acta Médica Portuguesa     Open Access  
Acta Medica Saliniana     Open Access  
Acta Scientiarum. Health Sciences     Open Access  
Acupuncture & Electro-Therapeutics Research     Full-text available via subscription   (Followers: 2)
Addiction Science & Clinical Practice     Open Access   (Followers: 7)
Addictive Behaviors Reports     Open Access   (Followers: 6)
Advanced Health Care Technologies     Open Access   (Followers: 4)
Advanced Science, Engineering and Medicine     Partially Free   (Followers: 7)
Advances in Bioscience and Clinical Medicine     Open Access   (Followers: 5)
Advances in Clinical Chemistry     Full-text available via subscription   (Followers: 29)
Advances in Life Course Research     Hybrid Journal   (Followers: 8)
Advances in Lipobiology     Full-text available via subscription   (Followers: 2)
Advances in Medical Education and Practice     Open Access   (Followers: 26)
Advances in Medical Sciences     Hybrid Journal   (Followers: 6)
Advances in Medicinal Chemistry     Full-text available via subscription   (Followers: 5)
Advances in Medicine     Open Access   (Followers: 2)
Advances in Microbial Physiology     Full-text available via subscription   (Followers: 4)
Advances in Molecular Oncology     Open Access   (Followers: 1)
Advances in Molecular Toxicology     Full-text available via subscription   (Followers: 8)
Advances in Parkinson's Disease     Open Access  
Advances in Phytomedicine     Full-text available via subscription  
Advances in Preventive Medicine     Open Access   (Followers: 6)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 20)
Advances in Therapy     Hybrid Journal   (Followers: 5)
Advances in Veterinary Science and Comparative Medicine     Full-text available via subscription   (Followers: 13)
Advances in Virus Research     Full-text available via subscription   (Followers: 5)
Advances in Wound Care     Hybrid Journal   (Followers: 10)
African Health Sciences     Open Access   (Followers: 2)
African Journal of Biomedical Research     Open Access  
African Journal of Clinical and Experimental Microbiology     Open Access   (Followers: 1)
African Journal of Laboratory Medicine     Open Access   (Followers: 2)
African Journal of Medical and Health Sciences     Open Access   (Followers: 2)
African Journal of Trauma     Open Access  
Afrimedic Journal     Open Access   (Followers: 2)
Aggiornamenti CIO     Hybrid Journal   (Followers: 1)
AIDS Research and Human Retroviruses     Hybrid Journal   (Followers: 8)
AJOB Primary Research     Partially Free   (Followers: 3)
Aktuelle Ernährungsmedizin     Hybrid Journal   (Followers: 4)
Al-Azhar Assiut Medical Journal     Open Access  
Alexandria Journal of Medicine     Open Access   (Followers: 1)
Allgemeine Homöopathische Zeitung     Hybrid Journal   (Followers: 2)
Alpha Omegan     Full-text available via subscription  
ALTEX : Alternatives to Animal Experimentation     Open Access   (Followers: 3)
American Journal of Biomedical Engineering     Open Access   (Followers: 11)
American Journal of Biomedical Research     Open Access   (Followers: 2)
American Journal of Biomedicine     Full-text available via subscription   (Followers: 6)
American Journal of Chinese Medicine, The     Hybrid Journal   (Followers: 5)
American Journal of Clinical Medicine Research     Open Access   (Followers: 5)
American Journal of Family Therapy     Hybrid Journal   (Followers: 11)
American Journal of Law & Medicine     Full-text available via subscription   (Followers: 12)
American Journal of Lifestyle Medicine     Hybrid Journal   (Followers: 5)
American Journal of Managed Care     Full-text available via subscription   (Followers: 11)
American Journal of Medical Case Reports     Open Access   (Followers: 1)
American Journal of Medical Sciences and Medicine     Open Access   (Followers: 1)
American Journal of Medicine     Hybrid Journal   (Followers: 46)
American Journal of Medicine and Medical Sciences     Open Access   (Followers: 1)
American Journal of Medicine Studies     Open Access  
American Journal of Medicine Supplements     Full-text available via subscription   (Followers: 3)
American Journal of the Medical Sciences     Hybrid Journal   (Followers: 12)
American Journal on Addictions     Hybrid Journal   (Followers: 9)
American Medical Journal     Open Access   (Followers: 4)
American medical news     Free   (Followers: 3)
American Medical Writers Association Journal     Full-text available via subscription   (Followers: 2)
Amyloid: The Journal of Protein Folding Disorders     Hybrid Journal   (Followers: 4)
Anales de la Facultad de Medicina     Open Access  
Anales de la Facultad de Medicina, Universidad de la República, Uruguay     Open Access  
Anales del Sistema Sanitario de Navarra     Open Access   (Followers: 1)
Analgesia & Resuscitation : Current Research     Hybrid Journal   (Followers: 3)
Anatomical Science International     Hybrid Journal   (Followers: 2)
Anatomical Sciences Education     Hybrid Journal   (Followers: 1)
Anatomy Research International     Open Access   (Followers: 2)
Angewandte Schmerztherapie und Palliativmedizin     Hybrid Journal  
Angiogenesis     Hybrid Journal   (Followers: 3)
Annales de Pathologie     Full-text available via subscription  
Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale     Full-text available via subscription   (Followers: 3)
Annals of African Medicine     Open Access   (Followers: 1)
Annals of Anatomy - Anatomischer Anzeiger     Hybrid Journal   (Followers: 2)
Annals of Bioanthropology     Open Access   (Followers: 3)
Annals of Biomedical Engineering     Hybrid Journal   (Followers: 18)
Annals of Biomedical Sciences     Full-text available via subscription   (Followers: 3)
Annals of Clinical Microbiology and Antimicrobials     Open Access   (Followers: 8)
Annals of Family Medicine     Open Access   (Followers: 12)
Annals of Fundeni Hospital     Open Access   (Followers: 1)
Annals of Ibadan Postgraduate Medicine     Open Access  
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Medicine     Hybrid Journal   (Followers: 12)
Annals of Medicine and Surgery     Open Access   (Followers: 5)
Annals of Microbiology     Hybrid Journal   (Followers: 10)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Saudi Medicine     Open Access  
Annals of the New York Academy of Sciences     Hybrid Journal   (Followers: 5)
Annals of The Royal College of Surgeons of England     Full-text available via subscription   (Followers: 3)
Annual Reports in Medicinal Chemistry     Full-text available via subscription   (Followers: 7)
Annual Reports on NMR Spectroscopy     Full-text available via subscription   (Followers: 4)
Annual Review of Medicine     Full-text available via subscription   (Followers: 18)
Anthropological Review     Open Access   (Followers: 24)
Anthropologie et santé     Open Access   (Followers: 5)
Antibiotics     Open Access   (Followers: 9)
Antibodies     Open Access   (Followers: 2)
Antibody Technology Journal     Open Access   (Followers: 1)
Anuradhapura Medical Journal     Open Access  
Anwer Khan Modern Medical College Journal     Open Access   (Followers: 2)
Apmis     Hybrid Journal   (Followers: 1)
Apparence(s)     Open Access   (Followers: 1)
Applied Clinical Informatics     Hybrid Journal   (Followers: 2)
Applied Medical Informatics     Open Access   (Followers: 11)
Arab Journal of Nephrology and Transplantation     Open Access   (Followers: 1)
Arak Medical University Journal     Open Access  
Archive of Clinical Medicine     Open Access   (Followers: 1)
Archive of Community Health     Open Access  
Archives of Biomedical Sciences     Open Access   (Followers: 7)
Archives of Medical and Biomedical Research     Open Access   (Followers: 3)
Archives of Medical Laboratory Sciences     Open Access   (Followers: 1)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Archives of Trauma Research     Open Access   (Followers: 2)
Archivos de Medicina (Manizales)     Open Access  
ArgoSpine News & Journal     Hybrid Journal  
Arquivos Brasileiros de Oftalmologia     Open Access  
Arquivos de Ciências da Saúde     Open Access  
Arquivos de Medicina     Open Access  
ARS Medica Tomitana     Open Access   (Followers: 1)
Art Therapy: Journal of the American Art Therapy Association     Full-text available via subscription   (Followers: 10)
Arterial Hypertension     Open Access  
Artificial Intelligence in Medicine     Hybrid Journal   (Followers: 12)
Artificial Organs     Hybrid Journal   (Followers: 1)
Asia Pacific Family Medicine     Open Access  
Asia Pacific Journal of Clinical Nutrition     Full-text available via subscription   (Followers: 9)
Asia Pacific Journal of Clinical Trials : Nervous System Diseases     Open Access  
Asian Bioethics Review     Full-text available via subscription   (Followers: 2)
Asian Journal of Cell Biology     Open Access   (Followers: 6)
Asian Journal of Health     Open Access   (Followers: 3)
Asian Journal of Medical and Biological Research     Open Access   (Followers: 2)
Asian Journal of Medical and Pharmaceutical Researches     Open Access   (Followers: 1)
Asian Journal of Medical Sciences     Open Access   (Followers: 1)
Asian Journal of Scientific Research     Open Access   (Followers: 2)
Asian Journal of Transfusion Science     Open Access   (Followers: 2)
Asian Medicine     Hybrid Journal   (Followers: 4)
ASPIRATOR : Journal of Vector-borne Disease Studies     Open Access  
Astrocyte     Open Access  
Atención Familiar     Open Access  
Atención Primaria     Open Access   (Followers: 1)
Audiology - Communication Research     Open Access   (Followers: 8)
Auris Nasus Larynx     Full-text available via subscription  
Australian Coeliac     Full-text available via subscription   (Followers: 2)
Australian Family Physician     Full-text available via subscription   (Followers: 3)
Australian Journal of Medical Science     Full-text available via subscription   (Followers: 1)
Autopsy and Case Reports     Open Access  
Aviation, Space, and Environmental Medicine     Full-text available via subscription   (Followers: 10)
Avicenna     Open Access   (Followers: 2)
Avicenna Journal of Medicine     Open Access   (Followers: 1)
Bangabandhu Sheikh Mujib Medical University Journal     Open Access   (Followers: 1)
Bangladesh Journal of Anatomy     Open Access   (Followers: 1)
Bangladesh Journal of Bioethics     Open Access  
Bangladesh Journal of Medical Biochemistry     Open Access   (Followers: 3)
Bangladesh Journal of Medical Education     Open Access   (Followers: 2)
Bangladesh Journal of Medical Microbiology     Open Access   (Followers: 3)
Bangladesh Journal of Medical Physics     Open Access  
Bangladesh Journal of Medical Science     Open Access  
Bangladesh Journal of Medicine     Open Access   (Followers: 1)
Bangladesh Journal of Physiology and Pharmacology     Open Access  
Bangladesh Journal of Scientific Research     Open Access   (Followers: 2)
Bangladesh Medical Journal     Open Access  
Bangladesh Medical Journal Khulna     Open Access  
Bangladesh Medical Research Council Bulletin     Open Access  
Basal Ganglia     Hybrid Journal  
Basic Sciences of Medicine     Open Access   (Followers: 2)
BBA Clinical     Open Access  
BC Medical Journal     Free  
Benha Medical Journal     Open Access  
Bijblijven     Hybrid Journal  
Bijzijn     Hybrid Journal   (Followers: 2)
Bijzijn XL     Hybrid Journal   (Followers: 1)
Bio-Algorithms and Med-Systems     Hybrid Journal   (Followers: 1)
BioDiscovery     Open Access   (Followers: 2)
Bioelectromagnetics     Hybrid Journal   (Followers: 1)
Bioengineering & Translational Medicine     Open Access  
Bioethics     Hybrid Journal   (Followers: 14)
Bioethics Research Notes     Full-text available via subscription   (Followers: 14)
Biologics in Therapy     Open Access  
Biology of Sex Differences     Open Access   (Followers: 3)

        1 2 3 4 5 6 7 8 | Last

Journal Cover American Medical Journal
  [4 followers]  Follow
    
  This is an Open Access Journal Open Access journal
   ISSN (Print) 1949-0070 - ISSN (Online) 1949-0089
   Published by Science Publications Homepage  [28 journals]
  • Is Air Pollution Controlled Enough' “Tapered
           Probabilities” Answer

    • Abstract: Air pollution is dangerous sespecially to the residents in cities, as it causes lung, heart, or respiratory illness. Public health professionals ponder whether the air pollution is significantly controilled. The amount of existing air pollution is measurable, but not its regulated level, which is therefore as a parameter in a novel manner in this article. However, there is no suitable methodology in the literature to extract and test whether the an estimated data evidence about the regulated air pollution level is significant. To fulfill the need, this article constructs a methodology based on tapered probability model for the air pollution data. Our new methodology is demonstrated using the air pollution data in African, American, Asian, European and Oceanic continents.
       
  • Level of Non-Matching Primary Transplant Cases According to Repeat
           Transplants Cases and a New Bivariate Poisson Distribution

    • Abstract: In their practice, healthcare administrators and professionals often wonder about the non-matching level organs in transplants for the sake of future forecasting. Currently, there is no appropriate methodology to analyze the pertinent transplant data and describe the patterns. The lack of a suitable methodology in the literature originates from an incorrect impression that the primary transplant cases and the repeat transplant cases are two separate and independent Poisson probability processes. In fact, the actual data on the primary and repeat transplant cases in USA during the year 2014 indicate otherwise with a high degree of correlation between them. One wonders about the missing link and it hides in their model as this article articulates. The aims of this article are set to find an appropriate underlying model for the data and then construct an analytic methodology. In this research process, a novel and useful bivariate probability distribution is discovered and it is named here "seemingly independent bivariate Poisson distribution" for a lack of better title. Its statistical properties are derived, explained and illustrated. This new bivariate distribution helps not only to estimate the non-matching level of organs in the transplant cases but also to project the number of repeat transplant cases based on knowing the number of primary transplant cases and vice versa.
       
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  • What is Missing in STD Screening in Hong Kong?

    • Abstract: This retrospective analysis was to study the prevalence of Sexually Transmitted Diseases (STD) in a Reproductive Medical Center in Hong Kong. A total of 1190 patients were included in this study. Group 1A, couples had no symptoms but presented with subinfertility; Group 1B, the subfertile couples were positive for either Chlamydia trachomatis (CT) or Ureaplasma urealyticum (UU); Group 2, couples with symptoms were offered full STD screening including CT, UU, Mycoplasma hominis (MH), Neisseria gonorrhoea (NG), Syphilis, Herpes Simplex Virus 1 and 2. The methods of ELISA and quantitative real-time PCR were used for these analyses. Group 1A: UU detection rates in both male and female (13.84 v.s. 37.07%) were significantly higher than that of CT (5.65 v.s. 5.57%); Group 1B and Group 2: For those who had Full STD check, UU and MH detection rates were significantly higher than that of CT (35, 13.7 and 7.1% respectively). Over 47% of patients showed positive for one or more organism. In the subfertile couples, the UU and CT detection rates were much higher in females than those in males. Both semen and urine samples gave the same rates of infection among CT, UU, NG and MH. U. urealyticum infection rate rather than Chlamydis trachomatis infection is highest in Hong Kong. The infection rate in females is higher than in males. The detection rates in semen and urine samples in males are similar.
       
  • Self Medication with Antibiotics among Medical and Pharmacy Students in
           North India

    • Abstract: Self medication practices among the medical and paramedical professionals have been reported in many countries, however, very limited research was done exclusively on antibiotic in North India. This study was designed to assess the prevalence and pattern of antibiotic usage for self diagnosed diseases among the medical and pharmacy students. This was a questionnaire based cross sectional study conducted among medical and pharmacy students in North India. A total 326 students participated in the study and data of 316 students were eligible for analysis. 57.63% medical and 66.9% pharmacy students reported to use antibiotics in last one year. Fever was the predominant ailments for which medical (48.41%) and pharmacy (46.88%) students' self medicated. Most of the medical (74.6%) and pharmacy (61.9%) students had preferred amoxicillin for their ailments. The majority of medical students, 65.87% have self medicated because of their pharmacological knowledge in contrast to 62.1% pharmacy students. Adverse drug reaction experienced by 29.36% and 11.7% medical and pharmacy students respectively. Statistically no significant difference was observed in antibiotic usage between medical and pharmacy students (p = 0.08). To curb the growing trend of this unethical practices students of health care professional needs to be educated.
       
  • A Case Vignette and Review of Maladaptive Denial and Related Ethical
           Issues

    • Abstract: Maladaptive denial is a pathological reaction to the symptoms, signs or diagnosis of a physical illness. The dominant response is persistent denial of having the physical disorder. Maladaptive denial typically results in the inability of the patient to provide informed consent to treatment due to the refusal to acknowledge an underlying disease process. This pathologic behavior exposes the affected individual to a significantly higher risk of serious physical illness or death. This paper describes a patient with maladaptive denial to his diagnosis of stage IV Non-Hodgkin's lymphoma which results in his death. The authors de fine the disorder, discuss the common ethical issues that arise when taking care of patients with maladaptive denial and summarize the recommended management.
       
  • Knowledge of Chemical Hazards and Prevalence of Darkroom Diseases among
           Darkroom Technicians and Assistants in Southeast, Nigeria

    • Abstract: Darkroom technicians and assistants are exposed daily to x-ray processing chemicals. These chemicals contain known irritants which can cause some disease symptoms to its handlers. The aim of this study was to assess the knowledge of chemical hazards and prevalence of darkroom diseases among darkroom technicians and assistants in Southeast, Nigeria. The study adopted cross-sectional survey. A total of 105 darkroom technicians and assistants who met the inclusion criteria in the 10 tertiary hospitals in Southeast, Nigeria were enlisted in the study. Data were collected using researcher-developed questionnaire and on-the-spot assessment of adequacy of ventilation in the darkroom. The questionnaire sought data on demographic variables, knowledge of the constituents of the processing chemicals, adherences to operating guidelines, knowledge of possible side effects, any observed sudden episodes of ill health and presence of workshops for new employees and older staff. The reliability of the instrument was conducted using test re-test in two tertiary hospitals in Southwest Nigeria. The internal consistency was calculated using Cronbach alpha which yielded a co-efficient of 0.82. A total of 105 questionnaires were administered and 100 copies properly completed and returned giving a return rate of 95.2%. 72% of the respondents had knowledge (mean = 3.20±0.71) of chemical hazard associated with x-ray processing chemicals while 34% had knowledge (mean = 3.12±1.3) of the constituents of the processing chemicals. Forty-four respondents (44%) always read the enclosed Materials Safety Data Sheet (MSDS) (mean = 2.57±1.1) before mixing the chemicals. The prevalence of darkroom disease among darkroom technicians and assistant in Southeast, Nigeria from our study was 68%. There were no significant differences (p>0.05) on the knowledge of darkroom disease, constituents of the processing chemicals and attention to Material Safety Data Sheet (MSDS) among darkroom technicians and assistants of different educational levels. There was high knowledge of chemical hazards among darkroom technicians and assistants from our study. However poor knowledge of the constituents of the processing chemicals and poor attention to the MSDS were noted to contribute to increase in the prevalence of the diseases.
       
  • Visual Curvatures of H1N1 Incidences in African, Asian, European, American
           and Oceanic Nations

    • Abstract: The World Health Organization (WHO) was worried about the outbreak of H1N1 epidemic worldwide as it consumed several human lives. In a novel manner, this article defines, computes and illustrates the effectiveness of health administrators’ efforts to extinguish pandemic H1N1 using curvature concept. Data on weekly incidences of H1N1 in year 2009 among the nations in Africa, Asia, Europe, Americas and Oceanic continents are utilized to compare continents and nations within the continent. A knowledge discovery from the data analysis of 2009 incidences is a necessity before any future incidences erupt. For stochastic reasons, which are stated and explained in the article, an Incidence Rate Restricted Inverse Binomial Distribution (IRRIBD) is introduced in this article to be an appropriate underlying model for the data. The plasticity of IRRIBD to explain the dynamics of the influenza is investigated. The actual H1N1 incidences during 2009 are analyzed and interpreted using IRRIBD in the illustration.
       
  • An Evaluation of Naloxone Use for Opioid Overdoses in West Virginia: A
           Literature Review

    • Abstract: Naloxone is a common treatment option for the reversal of an opioidoverdose. The law regulating naloxone varies from state to state and thereforeso does the drug’s availability. The state of Rhode Island has legalized naloxonefor over-the-counter use while a number of states allow prescriptions to opioidabusers and family members. The medical community as a whole appears to bedivided on the issue of availability to laypersons. This is largely due to a lack of information on this relatively newsubject, as well as discrepancies within the existing naloxone research in regardto the use of naloxone among the general public. This literature reviewprovides an objective examination of the pros and cons of increasing theavailability of naloxone to the public, with an emphasis on the state of WestVirginia (WV). Due to WV’s high rates of opioid abuse and overdose, theimplications of increasing public accessibility to naloxone could be invaluablein the effort to reduce opioid related deaths. To this end, a WV law that hasrecently gone into effect allows emergency personnel and family members ofopioid addicts to carry naloxone. Ongoing research investigations willdetermine the impact of this law in regard to the overall wellbeing of theresidents of WV and the implications on future laws regulating naloxone use.
       
  • Big Data in Medical Applications and Health Care

    • Abstract: Big Data can unify all patient related data to get a360-degree view of the patient to analyze and predict outcomes. It can improveclinical practices, new drug development and health care financing process. Itoffers a lot of benefits such as early disease detection, fraud detection andbetter healthcare quality and efficiency. This paper introduces the Big Data conceptand characteristics, health care data and some major issues of Big Data. Theseissues include Big Data benefits, its applications and opportunities in medicalareas and health care. Methods and technology progress about Big Data arepresented in this study. Big Data challenges in medical applications and healthcare are also discussed.
       
  • The Process of Porous Tantalum Implants Osseous Integration a Review

    • Abstract: Porous tantalum is a biomaterial that was recentlyintroduced in orthopaedics in order to overcome problems of the past related toimplant loosening. Its use has led to very good results, especially indifficult cases where severe bone defect is present, as it is found to haveosteoconductive and possibly, osteoinductive properties. So, it is of greatinterest to shed light to the mechanisms through which this material leads tonew bone formation after being implanted. For this reason, a review of thecurrent literature was undertook. Poroustantalum is, biologically, relatively inert, meaning that its bonding capacityto the bone is restricted. In order to overcome this obstacle, it undergoesthermal processing in alkaline environment. This process leads to extensivehydroxyapatite formation on its surface and thus, to better integration ofporous tantalum implants. Apart from this, new bone tissue formation occursinside the pores of porous tantalum after its implantation and this new boneretains the characteristics of normal bone, i.e., bone remodeling and Haversiansystems formation. This finding is enhanced by the observation that poroustantalum is an appropriate substrate for osteoblast adherence, proliferationand differentiation. Furthermore, the finding that osteoblasts derived from oldwomen (>60 years old) and cultivated on porous tantalum may grow faster thanosteoblasts taken from younger women (<45 years old) and cultivated on othersubstrates, can partially explain porous tantalum good performance in cases ofpatients with severe bone defects. In conclusion, porous tantalum chemical andmechanical properties are those that, probably, define the already noticed goodperformance of this material. However, further research is needed to totallyclarify the mechanisms through which they contribute to that.
       
  • PROBING NON-ADHERENCE TO PRESCRIBED MEDICINES' A BIVARIATE
           DISTRIBUTION WITH INFORMATION NUCLEUS CLARIFIES

    • Abstract: No illness gets cured without the patient’s adherence to the prescribed medicine (s). Reasons such as too many medicines, lack of health insurance coverage, high co-payment cost, loss of cognitive memory to take. are commonly noticed for non-adherence. In some illnesses, the patients who do not adhere to the prescribed medicines end up again in hospital. How should the pertinent data be analyzed to learn' Currently, there is no suitable methodology to scrutinize the data for a clear assessment about the significance of a reason. To fulfil such a need, this article develops and demonstrates a new underlying bivariate probability model for the data and a statistical methodology to extract pertinent information to check whether the non-adherent proportion of patients to medicine (s) is significant enough to come up with strict remedial policies. To start with, the case of too many prescribed medicines is examined. Then, the repeated hospitalization due to non-adherence is examined. The contents of this article could be easily extended to other reasons of non-adherence as well. In the presence of a reason, there might exist a number of non-adherent X and a number of adherent, Y patients. Both X and Y is observable in a sample of size n1 with the presence of a reason and in another random sample of size n2 with the absence of a reason. The total sample size is n = n1 + n2. Let 0
       
  • RADIOSENSITIZATION OF CANCER STEM CELLS: TARGETING TGFβ, NOTCH OR
           TELOMERASE TO IMPROVE TUMOR RESPONSE O RADIOTHERAPY

    • Abstract: Radiation resistant cancer stem cells are the main reason for treatment failure and tumor recurrence after cancer radiotherapy. Increasing biological evidences demonstrate that these cells possess the capacity to repair radiation induced DNA damage, protect themselves from radiation derived reactive oxygen species, survive and proliferate after several fractions of radiotherapy and finally, repopulate the heterogeneity of the tumor. Thus, targeting and eliminating these cells should be necessary to achieve cancer cure in radiotherapy. Three major approaches that specifically target radioresistant cancer stem cells have been recently investigated. First, inhibition of TGFβ, a major mediator of the tissue response to radiation, has been shown to induce radiosensitization of cancer stem cells by targeting the DNA damage response mechanism. Second, by preventing Notch activation during fractionated radiotherapy, cancer stem cells were depleted from their ability to repopulate the tumor after radiation. Finally, telomerase activity inhibitors have shown to specifically decrease the cancer stem cell population after radiotherapy. In the present review, we evaluate these radiosentitizing approaches and their possible effects when combined with fractionated radiotherapy as they promise to be a powerful tool in the battle against this cancer.
       
  • LACTIC ACIDOSIS AND HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS: A REVIEW OF THE
           LITERATURE

    • Abstract: Lactic acidosis is the most common cause of anion gap metabolic acidosis and is associated with high morbidity and mortality in hospitalized patients. The association between Hemophagocytic Lymphohistiocytosis (HLH) and lactic acidosis is still unclear. HLH causes cytokine overproduction which in turn induces lactic acidosis. There have been only few reports of type B lactic acidosis in HLH patients. There have been no studies addressing the outcome of cytokine removal for patients with HLH induced lactic acidosis. We reviewed literatures on HLH, focusing on its association with lactic acidosis and treatment options. This review demonstrates thatlactic acidosis in patients with HLH is under-recognized. Physicians should increase awareness of this association. In the setting of cytokine storm with multiorgan failure, cytokine removal with high blood flow, ultrafiltration rate and frequent membrane changes is a potential treatment option. More studies are urgently required to confirm this finding due to high morbidity and mortality of HLH.
       
  • SEROTONIN SYNDROME MASKED BY CONCOMITANT INGESTION OF ZOLOFT WITH
           BENZODIAZEPINE IN SUICIDE ATTEMPT IN A YOUNG HEALTHY MALE

    • Abstract: This case report discusses the history and management of a schizophrenic patient, a 18-year-old man, who had taken a massive overdose of clonazepam, abilify, depakote, zoloft and seroquel altogether. After discontinuation of these drugs and administration of cyproheptadine with IV fluids, he became hemo-dynamically stable. This case suggests that serotonin syndrome should be recognized promptly and complications need to be treated appropriately. Serotonin syndrome should be diagnosed surely to ensure the prompt initiation of the treatment including discontinuation of the precipitating drugs because the disease occasionally progresses rapidly to fatal condition. In addition, both the onset and resolution of symptoms are faster in serotonin syndrome.
       
  • POSTERIOR CEREBROVASCULAR ACCIDENTS AFTER PERCUTANEOUS CORONARY
           INTERVENTION

    • Abstract: Percutaneous Coronary Interventional procedures (PCIs) are recognised as gold standard treatment for high risks patients with diffuse coronary atherosclerosis. Neurologic complications are one of the most dreaded procedural outcomes, stroke after PCI affects mainly elderly and high-risk patients (age more than 80 years and use of intra-aortic balloon pump), with longer times of the procedure and angiographic complications, such as dissection, abrupt closure and no reflow. We report two consecutive cases of posterior CVAs after percutaneous coronary procedures involving the ponto-mesencephalon and the cerebellum. Especially when risk factors are present, careful attention should be devoted to the preparation of the patient and to minimize catheter manipulation and exchanges.
       
  • IMPACT OF DEHYDROEPIANDROSTERONE IN PREVENTION OF PARACETAMOL INDUCED
           NEPHROTOXICITY IN RATS

    • Abstract: Paracetamol (PCM) overdose can cause nephrotoxicity with oxidative stress as one of the possible mechanisms mediating the event. However, Dehydroepiandrosterone (DHEA), the major secretory product of the human adrenal gland, has been shown to possess a multi-targeted antioxidant activity which is also effective against lipid peroxidation induced in various animal models and against various human disorders. In this study, the preventive effect of DHEA against PCM-induced nephrotoxicity was examined. Rats were divided into four groups containing 10 rats each, as follows: A control: Received normal saline, Vehicle treated: Received the vehicle (5% DMSO), PCM model (750 mg kg-1), PCM and DHEA treated: Received concomitant dose of PCM (750 mg kg-1) + DHEA (250 mg kg-1), respectively, for 4 consecutive weeks. All treatment were given orally to animals. Our results show that co-treatment of DHEA with PCM prevented the PCM-induced nephrotoxicity and oxidative impairments of the kidney, as evidenced by a significantly reduced (p
       
  • PROBABLE CREUTZFELDT JAKOB DISEASE: CASE REPORT

    • Abstract: Prion diseases are associated with the accumulation of an abnormal isoformof cellular prion protein (PrPSc), which is the principal constituent of prions. Prions replicate in lymphoreticular tissues before neuroinvasion, suggesting that lymphoreticular biopsy samples may allow early diagnosis by detection of PrPSc. Creutzfeldt-Jakob Disease (CJD) is the most frequent prion disease in humans. Clinical diagnosis of sporadic (CJD) is based on the evaluation of rapidly progressive dementia, ataxia, myoclonus, changes on the electroencephalogram and other neurological signs. We report a problable (CJD) case in Santa Barbara surgical center, Rio de Janeiro, Brazil. From our clinical case, we decided to do a brief review about (CJD) researching at MedLine and Pubmed, using terms Creutzfeldt-Jakob disease and Prion diseases. A definite diagnosis, however, is confined to cases that have been evaluated neuropathlogically or by equivalent diagnostic techniques. The range in clinical expression of the disease is better appreciated and the existence of “atypical” cases of CJD is increasingly recognized. The clinical characteristics, laboratory findings, differential diagnosis, mechanisms of transmission and the actual therapeutic approach are discussed.
       
  • MOBILE COMMUNICATIONS FOR USING IN TELEMEDICINE

    • Abstract: Telemedicine the use of telecommunication and information technologies in order to provide clinical health care at a distance helps eliminate distance barriers and can improve access to medical services that would often not be consistently available in distant rural communities. It is also used to save lives in critical care and emergency situations. Although there were distant precursors to telemedicine, it is essentially a product of 20th century telecommunication and information technologies. These technologies permit communications between patient and medical staff with both convenience and fidelity, as well as the transmission of medical, imaging and health informatics data from one site to another. Early forms of telemedicine achieved with telephone and radio have been supplemented with video telephony, advanced diagnostic methods supported by distributed client/server applications and additionally with telemedical devices to support in-home care. There is a growing trend in the health domain to incorporate Smartphones and other wireless technologies to provide more efficient, cost effective and higher quality healthcare. With newer more sophisticated mobile devices for example, Smartphones this is an escalating practice. To date the use of mobile phone technology in the healthcare domain (mHealth) has been limited to uses such as disseminating information. However, mHealth is beginning to include software and data applications based on mobile devices and technologies. This movement is largely due to the advent of newer technologies associated with Smartphones. Some Smartphones can now be considered to be intelligent sensors with sensing capabilities such as Global Positioning System (GPS) location, proximity and accelerometers. This study examines the use of such technology in providing seamless mobile communications for telemedicine.
       
  • GENOTYPIC IDENTIFICATION OF CANDIDA SPP. ISOLATED FROM ONYCHOCANDIDIASIS
           PATIENTS BY PHENOTYPIC METHODS, PCR AND RAPD-PCR

    • Abstract: Candidal Onychomycosis (COM) is a common nail disease which plays as sources pathogenic reservoir giving a rise to repeated candidiasis infections. This study aimed to evaluate PCR assays and phenotypic tests for identification of yeasts isolated from COM patients. The study included 100 clinically suspected patients of COM attending the main hospital and clinics in Al-Dewania province in the middle of Iraq during September 2011 to April 2012. One hundred yeast isolates were identified morphologically by CHROMagar medium. DNA was extracted from 14 representative’s isolates for accurate identification by PCR and fingerprinted by RAPD-PCR. Phenotypic examination of 100 yeasts isolates on CHROMagar revealed that these isolates were classified into 7 different species belonged to Candida form genus, PCR assay revealed that primer pair ITS1 and ITS4 was successfully amplified ITS1-5.8S-ITS2 rDNA region for 14 isolates of Candida spp. yielding a unique PCR products approximately 510-650bp in length. The results of RAPD-PCR assay showed that both primers (TAGGATCAGA and AGGTCACTGA) were genotyped 14 isolates of Candida into seven main genotypes; three of these genotypes had highly percentage of homologous (80-100%) among related isolates were studied in each Candida isolates, while the others four genotypes had 10-50% homologous. This study concluded that for accurate and prices identification must used PCR and fingerprinted by RAPD-PCR assays, the results of CHROMagar were correlated with gene expression for each Candida isolates, while the results of RAPD PCR assay were correlated with degrees similarity and difference of genotypes for Candida isolates under interest.
       
  • VANCOMYCIN MIC CREEP AMONG METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS: A
           REPORT

    • Abstract: The objective of the study was to analyze the vancomycin MIC distribution against bloodstream MRSA isolates for a period of 1 year in India. This retrospective study analyzed 71 blood stream MRSA strains isolated at a tertiary care hospital in India between January 2008 and December 2008. The vancomycin MIC was determined by broth microdilution method. Only one isolate per patient was analyzed. The range of vanocmycin MIC for the 71 isolates in this study was varied between 0.25-3 µg mL-1. Only 29 isolates had MIC less than 1 µg mL-1 and 17 isolates MIC were more than 2 µg mL-1. In this study the phenomenon of vancomycin MIC creep was noticed in more than 75% of MRSA bloodstream isolates. We suggest further in vivo studies to determine the clinical significance of this MIC creep.
       
  • EFFECT OF BISPHENOL A ON PASSIVE AVOIDANCE PERFORMANCE IN MALE RATS

    • Abstract: Bisphenol A (BPA) is used to manufacture polycarbonate plastic products in resins lining metal cans, in dental sealants and in blends with other types of plastic products. In sharp contrast, there are many published studies that BPA has a wide range of significant adverse effects including structural and neurochemical changes throughout the brain associated with behavioral changes, such as hyperactivity, learning deficits and increased aggression in both males and females. So the aim of the present study was to investigate effect of BPA on learning and memory in passive avoidance learning model. Thirty six male Sprague Dawley rats weighing 180-260 g were used. The animals were divided into six groups: 1- control group (without any treatment) 2-sham group (received sesame oil the same volume as experimental, n = 6); 3-5 experimental (received BPA 5, 50, 100 and 150 mg kg-1 day, n = 24). BPA was administrated by oral intake by gavage for 15 days. Learning and memory were performed by shuttle-box. Data was analyzed by Kruskal-Wallis nonparametric test. The level of significance was considered P
       
  • DETECTING PATTERNS IN 5’ UNTRANSLATED REGIONS OF GENES INVOLVED IN
           THE REGULATION OF BLOOD PRESSURE AND OXIDATIVE STRESS

    • Abstract: Hypertension is a chronic physical condition with multifactorial causes. Although genetic factors have been associated to this pathological condition, characterization of the sequence patterns in the regulatory sites, for example, in 3’ or 5’ Untranslated Regions (UTR), remains to be explored. In particular, the 5’ UTR of genes associated with the regulation of blood pressure and oxidative stress are analyzed in this article. To gain insight into how certain DNA motifs are involved with high blood pressure, we decided to perform a study with sequences from genes reported as regulators of blood pressure and oxidative stress. 5’ UTR gene sequences were submitted to patterns recognition by the Multiple Em for Motif Elicitation (MEME) software. Afterward, the motifs obtained were searched for in the Transcription Element Search System (TESS) and Consite platforms, in order to identify the submitted sequence as element response of some transcription factor described previously. Three different motifs in each group of vasorelaxing-and vasocontractile-related gene sequences were detected. In the vasorelaxing group, motif lengths were 39 to 50 nucleotides and were located from -361 to -167 bp before the Open Reading Frame (ORF). In turn, motifs in vasocontractile group sequences were located from -619 to -570 nucleotides, with a length of from 18 to 40 nucleotides. Regarding the nucleic acid content in the motifs found, adenine was more prevalent in vasorelaxing-related sequences with 45% of the average frequency, whereas guanine on those vasocontractile-related sequences with 38%. Distinct motif sequences and variations of nucleotide content in the promoter region of vasorelaxing and vasocontractile-activity related genes were detected. These motifs of each group of genes, with a putative antagonistic role between them, might be a differential cis-regulatory elements of transcriptional machinery.
       
  • VELOCITY OF HEART RATE RECOVERY IN POST-EXERCISE UNDER DIFFERENT PROTOCOLS
           OF ACTIVE RECOVERY

    • Abstract: Abnormalities in the modulation of parasympathetic activity have been identified as a possible pathophysiological link with the association between decreases in heart rate recovery after exercise test. Hypothesis: To investigate if the application of different protocols of active recovery promotes difference in reducing Heart Rate (HR) in Post-Exercise (PE). This was a prospective, randomized trial of patients undergoing Exercise Testing (ET) and applied to two different protocols of active recovery. They were divided into G1 with recovery of 1.5 mph/2.5% and G2 40% of the speed and slope of the peak in the PE. Variables were evaluated pre-test and intrinsic to the TE. We compared the recovery of FC 1 and 2 min in the PE. Statistical analysis used the chi-square test, Student's t test and considered p
       
 
 
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