Subjects -> MEDICAL SCIENCES (Total: 8697 journals)
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MEDICAL SCIENCES (2419 journals)                  1 2 3 4 5 6 7 8 | Last

Showing 1 - 200 of 3562 Journals sorted alphabetically
16 de Abril     Open Access   (Followers: 4)
3D Printing in Medicine     Open Access   (Followers: 5)
4 open     Open Access  
AADE in Practice     Hybrid Journal   (Followers: 6)
AAS Open Research     Open Access   (Followers: 2)
ABCS Health Sciences     Open Access   (Followers: 8)
Abia State University Medical Students' Association Journal     Full-text available via subscription   (Followers: 3)
AboutOpen     Open Access  
ACIMED     Open Access   (Followers: 1)
ACS Medicinal Chemistry Letters     Hybrid Journal   (Followers: 50)
Acta Bio Medica     Full-text available via subscription   (Followers: 2)
Acta Bioethica     Open Access  
Acta Bioquimica Clinica Latinoamericana     Open Access   (Followers: 1)
Acta Científica Estudiantil     Open Access  
Acta Facultatis Medicae Naissensis     Open Access   (Followers: 1)
Acta Herediana     Open Access  
Acta Informatica Medica     Open Access   (Followers: 2)
Acta Medica (Hradec Králové)     Open Access  
Acta Medica Bulgarica     Open Access  
Acta Medica Colombiana     Open Access   (Followers: 1)
Acta Médica Costarricense     Open Access   (Followers: 2)
Acta Medica Indonesiana     Open Access  
Acta Medica International     Open Access  
Acta medica Lituanica     Open Access   (Followers: 1)
Acta Medica Marisiensis     Open Access   (Followers: 1)
Acta Medica Martiniana     Open Access  
Acta Medica Nagasakiensia     Open Access   (Followers: 1)
Acta Medica Peruana     Open Access   (Followers: 2)
Acta Médica Portuguesa     Open Access  
Acta Medica Saliniana     Open Access  
Acta Scientiarum. Health Sciences     Open Access   (Followers: 3)
Acupuncture & Electro-Therapeutics Research     Full-text available via subscription   (Followers: 8)
Acupuncture and Natural Medicine     Open Access  
Addiction Science & Clinical Practice     Open Access   (Followers: 9)
Addictive Behaviors Reports     Open Access   (Followers: 9)
Adıyaman Üniversitesi Sağlık Bilimleri Dergisi / Health Sciences Journal of Adıyaman University     Open Access   (Followers: 1)
Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi     Open Access   (Followers: 1)
Advanced Biomedical Research     Open Access  
Advanced Health Care Technologies     Open Access   (Followers: 10)
Advanced Science, Engineering and Medicine     Partially Free   (Followers: 9)
Advanced Therapeutics     Hybrid Journal   (Followers: 1)
Advances in Bioscience and Clinical Medicine     Open Access   (Followers: 8)
Advances in Cell and Gene Therapy     Hybrid Journal   (Followers: 2)
Advances in Clinical Chemistry     Full-text available via subscription   (Followers: 27)
Advances in Clinical Radiology     Full-text available via subscription   (Followers: 3)
Advances in Life Course Research     Hybrid Journal   (Followers: 11)
Advances in Lipobiology     Full-text available via subscription   (Followers: 2)
Advances in Medical Education and Practice     Open Access   (Followers: 32)
Advances in Medical Ethics     Open Access   (Followers: 3)
Advances in Medical Research     Open Access   (Followers: 2)
Advances in Medical Sciences     Hybrid Journal   (Followers: 10)
Advances in Medicinal Chemistry     Full-text available via subscription   (Followers: 6)
Advances in Medicine     Open Access   (Followers: 3)
Advances in Microbial Physiology     Full-text available via subscription   (Followers: 5)
Advances in Molecular Oncology     Open Access   (Followers: 2)
Advances in Molecular Toxicology     Full-text available via subscription   (Followers: 7)
Advances in Parkinson's Disease     Open Access   (Followers: 2)
Advances in Phytomedicine     Full-text available via subscription   (Followers: 1)
Advances in Preventive Medicine     Open Access   (Followers: 6)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 21)
Advances in Regenerative Medicine     Open Access   (Followers: 4)
Advances in Skeletal Muscle Function Assessment     Open Access  
Advances in Therapy     Hybrid Journal   (Followers: 5)
Advances in Traditional Medicine     Hybrid Journal   (Followers: 8)
Advances in Veterinary Science and Comparative Medicine     Full-text available via subscription   (Followers: 15)
Advances in Virus Research     Full-text available via subscription   (Followers: 6)
Advances in Wound Care     Hybrid Journal   (Followers: 14)
Aerospace Medicine and Human Performance     Full-text available via subscription   (Followers: 13)
African Health Sciences     Open Access   (Followers: 5)
African Journal of Biomedical Research     Open Access   (Followers: 1)
African Journal of Clinical and Experimental Microbiology     Open Access   (Followers: 4)
African Journal of Laboratory Medicine     Open Access   (Followers: 2)
African Journal of Medical and Health Sciences     Open Access   (Followers: 3)
African Journal of Thoracic and Critical Care Medicine     Open Access  
African Journal of Trauma     Open Access   (Followers: 1)
Afrimedic Journal     Open Access   (Followers: 3)
Aggiornamenti CIO     Hybrid Journal   (Followers: 1)
AIDS Research and Human Retroviruses     Hybrid Journal   (Followers: 9)
AJOB Empirical Bioethics     Hybrid Journal   (Followers: 3)
AJSP: Reviews & Reports     Hybrid Journal   (Followers: 1)
Aktuelle Ernährungsmedizin     Hybrid Journal   (Followers: 6)
Al-Azhar Assiut Medical Journal     Open Access   (Followers: 2)
Al-Qadisiah Medical Journal     Open Access   (Followers: 1)
Alerta : Revista Científica del Instituto Nacional de Salud     Open Access  
Alexandria Journal of Medicine     Open Access   (Followers: 1)
Allgemeine Homöopathische Zeitung     Hybrid Journal   (Followers: 3)
Alpha Omegan     Full-text available via subscription  
ALTEX : Alternatives to Animal Experimentation     Open Access   (Followers: 2)
Althea Medical Journal     Open Access   (Followers: 2)
American Journal of Biomedical Engineering     Open Access   (Followers: 15)
American Journal of Biomedical Research     Open Access   (Followers: 2)
American Journal of Biomedicine     Full-text available via subscription   (Followers: 7)
American Journal of Chinese Medicine, The     Hybrid Journal   (Followers: 4)
American Journal of Clinical Medicine Research     Open Access   (Followers: 8)
American Journal of Family Therapy     Hybrid Journal   (Followers: 10)
American Journal of Law & Medicine     Full-text available via subscription   (Followers: 12)
American Journal of Lifestyle Medicine     Hybrid Journal   (Followers: 7)
American Journal of Managed Care     Full-text available via subscription   (Followers: 13)
American Journal of Medical Case Reports     Open Access   (Followers: 3)
American Journal of Medical Sciences and Medicine     Open Access   (Followers: 5)
American Journal of Medicine     Hybrid Journal   (Followers: 50)
American Journal of Medicine and Medical Sciences     Open Access   (Followers: 1)
American Journal of Medicine Studies     Open Access   (Followers: 3)
American Journal of Medicine Supplements     Full-text available via subscription   (Followers: 3)
American Journal of the Medical Sciences     Hybrid Journal   (Followers: 12)
American Journal on Addictions     Hybrid Journal   (Followers: 11)
American medical news     Free   (Followers: 3)
American Medical Writers Association Journal     Full-text available via subscription   (Followers: 6)
Amyloid: The Journal of Protein Folding Disorders     Hybrid Journal   (Followers: 5)
Anales de la Facultad de Medicina     Open Access  
Anales de la Facultad de Medicina, Universidad de la República, Uruguay     Open Access  
Anales del Sistema Sanitario de Navarra     Open Access   (Followers: 1)
Analgesia & Resuscitation : Current Research     Hybrid Journal   (Followers: 7)
Anatolian Clinic the Journal of Medical Sciences     Open Access  
Anatomica Medical Journal     Open Access  
Anatomical Science International     Hybrid Journal   (Followers: 3)
Anatomical Sciences Education     Hybrid Journal   (Followers: 2)
Anatomy     Open Access   (Followers: 3)
Anatomy Research International     Open Access   (Followers: 4)
Androgens : Clinical Research and Therapeutics     Open Access   (Followers: 1)
Angewandte Schmerztherapie und Palliativmedizin     Hybrid Journal  
Angiogenesis     Hybrid Journal   (Followers: 3)
Ankara Medical Journal     Open Access   (Followers: 2)
Ankara Üniversitesi Tıp Fakültesi Mecmuası     Open Access  
Annales de Pathologie     Full-text available via subscription  
Annales des Sciences de la Santé     Open Access  
Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale     Full-text available via subscription   (Followers: 3)
Annals of African Medicine     Open Access   (Followers: 2)
Annals of Anatomy - Anatomischer Anzeiger     Hybrid Journal   (Followers: 3)
Annals of Bioanthropology     Open Access   (Followers: 5)
Annals of Biomedical Engineering     Hybrid Journal   (Followers: 19)
Annals of Biomedical Sciences     Full-text available via subscription   (Followers: 4)
Annals of Clinical Hypertension     Open Access  
Annals of Clinical Microbiology and Antimicrobials     Open Access   (Followers: 15)
Annals of Family Medicine     Open Access   (Followers: 18)
Annals of Health Research     Open Access   (Followers: 1)
Annals of Ibadan Postgraduate Medicine     Open Access  
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Medicine     Hybrid Journal   (Followers: 12)
Annals of Medicine and Surgery     Open Access   (Followers: 7)
Annals of Medicine and Surgery Case Reports     Open Access   (Followers: 1)
Annals of Medicine and Surgery Protocols     Open Access   (Followers: 1)
Annals of Microbiology     Hybrid Journal   (Followers: 13)
Annals of Musculoskeletal Medicine     Open Access   (Followers: 2)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Rehabilitation Medicine     Open Access   (Followers: 1)
Annals of Saudi Medicine     Open Access  
Annals of the College of Medicine, Mosul     Open Access   (Followers: 1)
Annals of the New York Academy of Sciences     Hybrid Journal   (Followers: 5)
Annals of The Royal College of Surgeons of England     Full-text available via subscription   (Followers: 3)
Annals of the RussianAacademy of Medical Sciences     Open Access   (Followers: 1)
Annual Reports in Medicinal Chemistry     Full-text available via subscription   (Followers: 7)
Annual Reports on NMR Spectroscopy     Full-text available via subscription   (Followers: 5)
Annual Review of Medicine     Full-text available via subscription   (Followers: 18)
Anthropological Review     Open Access   (Followers: 25)
Anthropologie et santé     Open Access   (Followers: 5)
Antibiotics     Open Access   (Followers: 9)
Antibodies     Open Access   (Followers: 2)
Antibody Reports     Open Access   (Followers: 1)
Antibody Technology Journal     Open Access   (Followers: 1)
Antibody Therapeutics     Open Access   (Followers: 1)
Anuradhapura Medical Journal     Open Access  
Anwer Khan Modern Medical College Journal     Open Access   (Followers: 2)
Apmis     Hybrid Journal   (Followers: 2)
Apparence(s)     Open Access   (Followers: 1)
Applied Clinical Informatics     Hybrid Journal   (Followers: 5)
Applied Clinical Research, Clinical Trials and Regulatory Affairs     Hybrid Journal   (Followers: 2)
Applied Medical Informatics     Open Access   (Followers: 14)
Arab Journal of Nephrology and Transplantation     Open Access   (Followers: 1)
Arabian Journal of Scientific Research / المجلة العربية للبحث العلمي     Open Access   (Followers: 1)
Archive of Biomedical Science and Engineering     Open Access   (Followers: 1)
Archive of Clinical Medicine     Open Access   (Followers: 1)
Archive of Community Health     Open Access   (Followers: 1)
Archives Medical Review Journal / Arşiv Kaynak Tarama Dergisi     Open Access  
Archives of Asthma, Allergy and Immunology     Open Access  
Archives of Clinical Hypertension     Open Access   (Followers: 2)
Archives of Medical and Biomedical Research     Open Access   (Followers: 3)
Archives of Medical Laboratory Sciences     Open Access   (Followers: 1)
Archives of Medicine and Health Sciences     Open Access   (Followers: 5)
Archives of Medicine and Surgery     Open Access   (Followers: 1)
Archives of Organ Transplantation     Open Access   (Followers: 2)
Archives of Preventive Medicine     Open Access   (Followers: 3)
Archives of Pulmonology and Respiratory Care     Open Access   (Followers: 2)
Archives of Renal Diseases and Management     Open Access   (Followers: 2)
Archives of Trauma Research     Open Access   (Followers: 4)
Archivos de Medicina (Manizales)     Open Access   (Followers: 1)
ArgoSpine News & Journal     Hybrid Journal  
Arquivos Brasileiros de Oftalmologia     Open Access   (Followers: 1)
Arquivos de Ciências da Saúde     Open Access  
Arquivos de Medicina     Open Access   (Followers: 1)
Ars Medica : Revista de Ciencias Médicas     Open Access  
ARS Medica Tomitana     Open Access   (Followers: 1)
Art Therapy: Journal of the American Art Therapy Association     Hybrid Journal   (Followers: 19)
Arterial Hypertension     Open Access   (Followers: 1)
Artificial Intelligence in Medicine     Hybrid Journal   (Followers: 20)
Artificial Organs     Hybrid Journal   (Followers: 1)
ASHA Leader     Open Access   (Followers: 6)
Asia Pacific Family Medicine Journal     Open Access   (Followers: 4)
Asia Pacific Journal of Clinical Nutrition     Full-text available via subscription   (Followers: 13)
Asia Pacific Journal of Clinical Trials : Nervous System Diseases     Open Access   (Followers: 1)

        1 2 3 4 5 6 7 8 | Last

Similar Journals
Journal Cover
Acta Medica Colombiana
Number of Followers: 1  

  This is an Open Access Journal Open Access journal
ISSN (Print) 0120-2448
Published by SciELO Homepage  [911 journals]
  • Cardiovascular events related to the use of macrolides in an intensive
           care unit

    • Abstract: Introduction and objectives: macrolides are widely used antibiotics for which a greater frequency of cardiovascular events related to increased arrhythmias has been reported. This study seeks to describe some cardiovascular complications of the use of macrolides in ICU patients. Materials and methods: this was a descriptive cross-sectional study which included adult patients admitted to the Medical Intensive Care Unit at the Fundación Cardioinfantil who received antibiotic treatment with clarithromycin in 2013 and 2015. Results: the collected sample was 38 patients. The median age was 64 years, and clarithromycin was most frequently used for treating community-acquired infections, with pneumonia being the most common diagnosis. The frequency of atrial fibrillation or flutter was 7.89%, and ventricular tachycardia 2.63%. The most frequently used concomitant medication was quetiapine at 28.95%. The main cause of death was respiratory failure. Conclusions: the frequency of arrhythmias was high in our study, although the most frequent cause of death was respiratory failure. (Acta Med Colomb 2020; 45.
      DOI :https://doi.org/10.36104/amc.2020.1336).Resumen Introducción y objetivos: los macrólidos son antibióticos ampliamente utilizados con los cuales se ha reportado una mayor frecuencia de eventos cardiovasculares relacionados con aumento de arritmias. Mediante este estudio, se busca describir algunas complicaciones cardiovasculares con el uso de macrólidos en pacientes en UCI. Materiales y métodos: se realizó un estudio descriptivo de corte transversal en el que se incluyeron pacientes adultos que ingresaron a la unidad de cuidado intensivo médico de la Fundación Cardioinfantil y que recibieron tratamiento antibiótico con claritromicina durante los años 2013 y 2015. Resultados: la muestra recolectada fue de 38 pacientes, la mediana de edad fue de 64 años y la claritromicina se usó más frecuentemente en el tratamiento de infecciones adquiridas en la comunidad, siendo la neumonía el diagnóstico más común. La frecuencia de arritmias tipo fibrilación o flutter auricular fue de 7.89% y de taquicardia ventricular 2.63%. El medicamento concomitante más frecuentemente usado fue la quetiapina con 28.95%. La principal causa de muerte fue falla respiratoria. Conclusiones: la frecuencia de arritmias fue alta en nuestro, aunque la causa de muerte más frecuente fue falla respiratoria.(Acta Med Colomb 2020; 45.
      DOI : https://doi.org/10.36104/amc.2020.1336).
       
  • Behavior of acute myocardial infarctions in an intensive care unit of a
           medium-size city over a one-year span

    • Abstract: Objectives: to identify the clinical and paraclinical behavior of myocardial infarctions in an intensive care unit of a medium-size city during 2017. Methods: a descriptive, cross-sectional study which included 99 medical records with a diagnosis of myocardial infarction on ICU discharge. The variables were described and analysis of variance and Chi2tests were performed, using a p-value less than 0.05 for statistically significant differences. Results: the prevalence of myocardial infarction in the ICU was 11.8%. The average age was 66.8 years. Chest pain was present in 82.8% with an average duration of 335 minutes. The pain most often radiated to the left arm (13.1%). Non-ST segment elevation myocardial infarction was the most frequent (50.5%), and the electrocardiogram located the infarctions on the inferior surface in 28.2%. The average ultrasensitive troponin I was 28.2 ng/mL. A total of 54.5% had complications. Mortality was 14.1%. Hospital stay was 6.5 and critical care stay was three days. There was a statistically significant relationship between chest pain and ST segment elevation (p<0.001) and between troponin I plus hospital stay and ST segment elevation (p=0.007 and p=0.003, respectively). Conclusion: the study showed that 11.8% of patients admitted to ICU are admitted for myocardial infarction, and there is a statistically significant relationship between chest pain and an elevated ST segment and between increased troponin I plus a longer hospital stay and ST segment elevation. (Acta Med Colomb 2020; 45.
      DOI : https://doi.org/10.36104/amc.2020.1498).Resumen Identificar el comportamiento clínico y paraclínico del infarto de miocardio en una unidad de cuidados intensivos de una ciudad intermedia durante el 2017. Métodos: estudio descriptivo de corte transversal, incluyó 99 registros con diagnóstico de infarto del miocardio al egreso de UCI. Se describieron las variables y se realizaron análisis de varianza y chi2y se consideró un valor de p<0.05 para diferencias estadísticamente significativas. Resultados: la prevalencia de infarto del miocardio fue 11.8% en UCI. La edad promedio fue 66.8 años. El dolor precordial estuvo presente en 82.8% con una duración promedio de 335 minutos. La irradiación del dolor fue más frecuente a miembro superior izquierdo (13.1%). El infarto sin elevación del complejo ST fue más frecuente (50.5%). Y la localización electrocardiográfica fue en la cara inferior en 28.2%. El promedio de troponina I ultrasensible fue de 28.2 ng/mL. Presentaron complicaciones el 54.5%. La mortalidad fue de 14.1%. La estancia hospitalaria fue 6.5 y la estancia en cuidados críticos tres días. Se encontró relación estadísticamente significativa entre dolor precordial y elevación del segmento ST (p<0.001) y entre troponina I con estancia hospitalaria y elevación del segmento ST (p=0.007 y p=0.003 respectivamente). Conclusión: se identificó que 11.8% de los pacientes que ingresan a la UCI, lo hacen por infarto del miocardio, y una relación estadísticamente significativa entre dolor precordial con elevación del segmento ST y entre el aumento de troponina I con mayor estancia hospitalaria y elevación del segmento ST.(Acta Med Colomb 2020; 45.
      DOI :https://doi.org/10.36104/amc.2020.1498).
       
  • The diagnostic yield of three clinical prediction rules for pulmonary
           embolism

    • Abstract: Objective: pulmonary embolism (PE) is the third cause of cardiovascular death worldwide. The evaluation of pre-test probability using the Wells, Geneva and Pisa clinical prediction rules has been amply validated in prior studies. However, there are insufficient data for evaluating their diagnostic yield in a Colombian population. The goal of this article is to evaluate the yield of these scales in our population. Methods: this was a retrospective cohort study with diagnostic test analysis in a tertiary level hospital from 2009 to 2017, which included all subjects over the age of 18 who had undergone a chest computed tomography angiography (CTA) due to a clinical suspicion of PE. All the necessary variables for constructing the Wells, Geneva and Pisa rules were recorded. Each score was calculated numerically and then classified according to probability. Pulmonary embolism was diagnosed through a CTA read by a radiologist. The data were entered on an Excel spreadsheet and analyzed using a licensed SPSS statistical program. Results: a total of 507 subjects were included for Wells and Geneva scores and 339 for the Pisa score. The average age was 56 years (SD: 19.8) and 56.6% were males. A statistically significant relationship was found between the different calculated scores and the diagnosis of pulmonary embolism: low, intermediate and high Wells probability p<0.001; less probable and probable Wells p<0.001; low, intermediate and high Geneva p=0.006; and low, intermediate, moderate and high Pisa p=0.001. The ACOR for Wells was 0.715 (95% CI:0.663-0.767) (p<0.001), for Geneva was 0.611 (95% CI:0.553-0.668) (p<0.001), and for Pisa was 0.643 (95% CI:0.574-0.713) (p<0.001). Conclusions: the study showed a greater PE diagnostic yield using the Wells score in our setting. There are limitations to the application and development of the Pisa score asociated with a lower yield in our patients.(Acta Med Colomb 2020; 45.
      DOI :https://doi.org/10.36104/amc.2020.1384).Resumen Objetivo: la embolia pulmonar (EP) es la tercera causa de muerte cardiovascular en el mundo. La evaluación de la probabilidad pre test a través de reglas de predicción clínica Wells, Ginebra y Pisa ha sido ampliamente validada en estudios previos. Sin embargo, hay datos insuficientes que evalúen el rendimiento diagnóstico de las mismas en población colombiana, este artículo tiene como fin evaluar el rendimiento de estas escalas en nuestra población. Métodos: estudio de cohorte retrospectivo con análisis de prueba diagnóstica en un hospital de III nivel de atención entre los años 2009 y 2017, donde se incluyeron todos los sujetos mayores de 18 años con realización de angiotomografía de tórax (ATC) solicitada por sospecha clínica de EP. Se registraron todas las variables necesarias para la construcción de las reglas de Wells, Ginebra y Pisa. Cada uno de los puntajes se calculó de manera numérica y posteriormente se clasificó según la probabilidad. El diagnóstico de EP se realizó mediante ATC leída por radiólogo. Los datos se ingresaron en una hoja de cálculo de Excel y se analizaron con el programa estadístico SPPS licenciado. Resultados: se ingresaron 507 sujetos para los puntajes de Wells y Ginebra y 339 para el puntaje de Pisa. El promedio de edad fue de 56 años (DS:19.8) y 56.6% de sexo masculino, se encontró una relación estadísticamente significativa entre los diferentes puntajes evaluados y el diagnóstico de embolia pulmonar, Wells probabilidad baja, intermedia y alta p<0.001, Wells menos probable y probable p<0.001, Ginebra bajo, intermedio y alto p=0.006, Pisa bajo, intermedio, moderada y alta p=0.001. El ACOR para Wells fue 0.715(IC95%:0.663-0.767) (p<0.001), Ginebra 0.611(IC95%:0.553-0.668) (P<0.001), Pisa 0.643(IC95%:0.574-0.713) (p<0.001). Conclusiones: se determinó un rendimiento superior para el diagnóstico de EP con el puntaje de Wells en nuestro medio, hay limitaciones con la aplicación y desarrollo del puntaje de Pisa asociado a un rendimiento inferior en nuestros pacientes.(Acta Med Colomb 2020; 45.
      DOI :https://doi.org/10.36104/amc.2020.1384).
       
  • Characterization of patients with early vs. late-onset Alzheimer's
           dementia

    • Abstract: Introduction: Alzheimer's dementia (AD) has an early and a late onset. More information is needed regarding risk factors according to the age of onset of AD. The objective is to characterize the sociodemographic, anthropometric, laboratory and genetic variables as well as the history of patients with ade novodiagnosis of AD, by age of onset, at the Hospital Universitario C.A.R.I.'s mental health site over a period of two years. Methods: a cross-sectional descriptive study of 39 patients with ade novodiagnosis of AD. A questionnaire was completed, paraclinical studies were ordered and a blood sample was obtained for APOE genotyping. The IBM SPSS 21 software was used for analysis. Results: 82.05% had late-onset and 17.95% had early-onset AD. Of those with early-onset AD, 57.14% were females, as were 71.90% of those with late-onset AD. 71.44% of those with early-onset AD were married and 53.12% with late-onset AD were widowed. Only 14.29% with early-onset and 18.75% with late-onset AD had optimal LDL levels. Altogether, 79.49% of the population was heterozygous for the ε4 allele. 71.43% of those with early-onset AD had a family history of dementia. Discussion: age is the main factor associated with AD and females were more frequent in both groups. Social relationships play a role in early detection of symptoms. Lipid profile abnormalities were seen in both groups. Having at least one ε4 allele is a frequent finding in AD. Having a first-degree relative with dementia and/or Alzheimer's was more frequent in early-onset AD.(Acta Med Colomb 2020; 45.
      DOI : https://doi.org/10.36104/amc.2020.1316).Resumen Introducción: la demencia de tipo Alzheimer (DTA) tiene presentación precoz o tardía. Es necesaria mayor información sobre factores de riesgo según edad de aparición de DTA. El objetivo es caracterizar variables sociodemográficas, antropométricas, de laboratorio, genéticas y antecedentes en pacientes con diagnósticode novode DTA según edad de aparición en el Hospital Universitario C.A.R.I. sede salud mental en un periodo de dos años. Metodología: estudio descriptivo transversal con 39 pacientes con diagnósticode novode DTA. Se realizó un cuestionario, solicitaron paraclínicos y se obtuvo una muestra sanguínea para genotipificación deAPOE.Se utilizó el software IBM SPSS 21 para análisis. Resultados: el 82.05% tenían DTA tardío y 17.95% DTA precoz. El 57.14% con DTA precoz y 71.90% con DTA tardía eran de sexo femenino. El 71.44% con DTA precoz eran casados y 53.12% con DTA tardío eran viudos. Solo 14.29% con DTA precoz y 18.75% con DTA tardío tenían niveles óptimos de LDL. El 79.49% de la población era heterocigoto para el alelo ε4. El 71.43% con DTA precoz tenía antecedente familiar de demencia. Discusión: la edad es el principal factor asociado a DTA y el sexo femenino fue más frecuente en ambos grupos. Las relaciones sociales juegan un rol en la identificación temprana de la sintomatología. Las alteraciones del perfil lipídico se evidenciaron en ambos grupos. Tener al menos un alelo ε4 es un hallazgo frecuente de DTA. Tener un familiar con demencia y/o Alzheimer de primer grado de consanguinidad fue más frecuente en DTA precoz.(Acta Med Colomb 2020; 45.
      DOI : https://doi.org/10.36104/amc.2020.1316).
       
  • Challenges for generations in higher education in health

    • Abstract: The characteristics of information and communication technology use in today's society create a series of challenges within health sciences higher education learning scenarios. The objective of this article is to present several problematic cases which illustrate these challenges and propose ways to handle them. The main element at the disposal of health sciences higher education professors is the establishment of rules and clear limits in the interaction with the new generations. Learning scenarios in which information technologies for communication are used in an emotionally safe atmosphere of trust should be the goal of curricula in health sciences higher education.(Acta Med Colomb 2020; 45.
      DOI :https://doi.org/10.36104/amc.2020.1649).Resumen Las características de uso de tecnologías de la información y la comunicación en la sociedad actual generan una serie de desafíos en los escenarios de aprendizaje para la educación superior en salud. Este artículo tiene como objetivo presentar varios casos problemáticos que dan cuenta de estos desafíos y propuestas de cómo manejarlos. El principal elemento con el que cuentan los profesores en educación superior en salud es el establecimiento de reglas y límites claros en el relacionamiento con las nuevas generaciones. Unos escenarios de aprendizaje que hagan uso de las tecnologías de la información en la comunicación, en un ambiente de confianza y emocionalmente seguros deberían ser el objetivo de los currículos en educación superior en salud.(Acta Med Colomb 2020; 45.
      DOI :https://doi.org/10.36104/amc.2020.1649).
       
  • Herpes simplex virus-1 encephalitis in a kidney transplant patient

    • Abstract: The incidence of herpes simplex virus-1 (HSV-1) infection in kidney transplant patients is 3% in those who have received antiviral prophylaxis versus 9.8% without prophylaxis. Herpes viruses usually cause mucocutaneous lesions and only occasionally cause visceral disease or central nervous system infection in immunosuppressed and immunocompetent patients. The gold standard for diagnosis is DNA detection using polymerase chain reaction (PCR) in the affected organ. According to the literature, it is treated with acyclovir, with which remission is expected in most cases without sequelae. Here we present the clinical case of a kidney transplant patient who had HSV-1 encephalitis (with the virus detected in the cerebrospinal fluid (CSF) through PCR), and received the standard treatment with complete recovery of his neurological state. (Acta Med Colomb 2020; 45.
      DOI : https://doi.org/10.36104/amc.2020.1387).Resumen La infección por herpes simple tipo 1 (HSV tipo 1) en los pacientes con trasplante renal tiene una incidencia de 3% en quienes han recibido profilaxis antiviral versus 9.8% sin profilaxis. Los virus herpes habitualmente producen lesiones mucocutáneas y sólo en ocasiones causan patología visceral o infección del sistema nervioso central en pacientes inmunosuprimidos e inmunocompetentes. La prueba de oro estándar para su diagnóstico es la detección del ADN mediante la reacción de cadena polimerasa (PCR) en el órgano afectado. El tratamiento de acuerdo con la literatura es con aciclovir, con el cual se espera una remisión de la enfermedad en la mayoría de los casos sin secuelas. A continuación, presentamos el caso clínico de un paciente con trasplante renal quien cursó con encefalitis por HSV tipo 1 detectado en líquido cefalorraquídeo (LCR) mediante PCR, quien recibió tratamiento estándar con recuperación completa de su estado neurológico.(Acta Med Colomb 2020; 45.
      DOI :https://doi.org/10.36104/amc.2020.1387).
       
  • Polyarteritis nodosa

    • Abstract: Polyarteritis nodosa was first described in 1866 by Zarco. Histologically, it is characterized by necrosis of the medium-sized arteries. Clinical case: A 63-year-old patient presented with myalgia, blurred vision, paresthesias and loss of muscle strength. On physical exam, he had hypesthesia in the left foot. Paraclinical studies ruled out small vessel vasculitis, and, in the end, the biopsy was compatible with polyarteritis nodosa. Discussion: this is a low prevalence entity with widely variable clinical manifestations. Therefore, the American College of Rheumatology criteria must be used for diagnosis, keeping in mind that the gold standard is histopathology. It is treated with immunosuppressants and the patient's prognosis is determined through the assessment of four criteria.(Acta Med Colomb 2020; 45.
      DOI :https://doi.org/10.36104/amc.2020.1388).Resumen La poliarteritis nodosa fue descrita por primera vez en 1866 por Zarco. Histológicamente se caracteriza por la presencia de necrosis de las arterias de mediano calibre. Caso clínico: paciente de 63 años con mialgias, visión borrosa, parestesias y pérdida de fuerza muscular. Al examen físico con hipoestesia en pie izquierdo. Los paraclínicos descartaron vasculitis de pequeño vasos, finalmente la biopsia era compatible con poliarteritis nodosa. Discusión: es una entidad de baja prevalencia, la cual tiene una amplia variabilidad en cuanto a manifestaciones clínicas, por lo cual es necesario usar los criterios del Colegio Americano de Reumatología para el diagnóstico, teniendo en cuenta que el gold estándar es el estudio histopatológico. El tratamiento se da con medicamentos inmunosupresores y el pronóstico del paciente se establece mediante la evaluación de cuatro criterios.(Acta Med Colomb 2020; 45.
      DOI :http://doi.org/10.36104/amc.2020.1388).
       
  • Moyamoya disease

    • Abstract: Moyamoya disease is a chronic neurovascular disease characterized by progressive bilateral stenosis of the internal carotid arteries with abnormal formation of new abnormal blood vessels whose blockage of blood flow causes a variety of clinical manifestations and complications associated with acute cerebrovascular events (ischemic or hemorrhagic), which may even be fatal. This article seeks to describe this entity, its incidence, prevalence, forms of presentation, therapeutic measures and prognosis through a clinical case report. (Acta Med Colomb 2020; 45.
      DOI :http://doi.org/10.36104/amc.2020.1424).Resumen La enfermedad de Moyamoya es una enfermedad neurovascular crónica caracterizada por una estenosis progresiva bilateral de las arterias carótidas internas, con la formación anormal de nuevos vasos sanguíneos, cuyo bloqueo en flujo sanguíneo ocasiona variadas manifestaciones clínicas y complicaciones asociadas a eventos cerebrovasculares (isquémicos o hemorrágicos) agudos que pueden llegar a ser incluso mortales. El presente artículo pretende realizar una aproximación acerca de esta entidad, su incidencia, prevalencia, formas de presentación y medidas terapéuticas y pronostico mediante el reporte de un caso clínico.(Acta Med Colomb 2020; 45.
      DOI :https://doi.org/10.36104/amc.2020.1424).
       
  • Ciprofloxacin-induced esophageal ulcers

    • Abstract: Moyamoya disease is a chronic neurovascular disease characterized by progressive bilateral stenosis of the internal carotid arteries with abnormal formation of new abnormal blood vessels whose blockage of blood flow causes a variety of clinical manifestations and complications associated with acute cerebrovascular events (ischemic or hemorrhagic), which may even be fatal. This article seeks to describe this entity, its incidence, prevalence, forms of presentation, therapeutic measures and prognosis through a clinical case report. (Acta Med Colomb 2020; 45.
      DOI :http://doi.org/10.36104/amc.2020.1424).Resumen La enfermedad de Moyamoya es una enfermedad neurovascular crónica caracterizada por una estenosis progresiva bilateral de las arterias carótidas internas, con la formación anormal de nuevos vasos sanguíneos, cuyo bloqueo en flujo sanguíneo ocasiona variadas manifestaciones clínicas y complicaciones asociadas a eventos cerebrovasculares (isquémicos o hemorrágicos) agudos que pueden llegar a ser incluso mortales. El presente artículo pretende realizar una aproximación acerca de esta entidad, su incidencia, prevalencia, formas de presentación y medidas terapéuticas y pronostico mediante el reporte de un caso clínico.(Acta Med Colomb 2020; 45.
      DOI :https://doi.org/10.36104/amc.2020.1424).
       
  • Superinfection

    • Abstract: Moyamoya disease is a chronic neurovascular disease characterized by progressive bilateral stenosis of the internal carotid arteries with abnormal formation of new abnormal blood vessels whose blockage of blood flow causes a variety of clinical manifestations and complications associated with acute cerebrovascular events (ischemic or hemorrhagic), which may even be fatal. This article seeks to describe this entity, its incidence, prevalence, forms of presentation, therapeutic measures and prognosis through a clinical case report. (Acta Med Colomb 2020; 45.
      DOI :http://doi.org/10.36104/amc.2020.1424).Resumen La enfermedad de Moyamoya es una enfermedad neurovascular crónica caracterizada por una estenosis progresiva bilateral de las arterias carótidas internas, con la formación anormal de nuevos vasos sanguíneos, cuyo bloqueo en flujo sanguíneo ocasiona variadas manifestaciones clínicas y complicaciones asociadas a eventos cerebrovasculares (isquémicos o hemorrágicos) agudos que pueden llegar a ser incluso mortales. El presente artículo pretende realizar una aproximación acerca de esta entidad, su incidencia, prevalencia, formas de presentación y medidas terapéuticas y pronostico mediante el reporte de un caso clínico.(Acta Med Colomb 2020; 45.
      DOI :https://doi.org/10.36104/amc.2020.1424).
       
 
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