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  Subjects -> MEDICAL SCIENCES (Total: 8250 journals)
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MEDICAL SCIENCES (2224 journals)                  1 2 3 4 5 6 7 8 | Last

Showing 1 - 200 of 3562 Journals sorted alphabetically
16 de Abril     Open Access   (Followers: 1)
3D Printing in Medicine     Open Access   (Followers: 4)
4 open     Open Access  
AADE in Practice     Hybrid Journal   (Followers: 6)
ABCS Health Sciences     Open Access   (Followers: 7)
Abia State University Medical Students' Association Journal     Full-text available via subscription   (Followers: 2)
ACIMED     Open Access   (Followers: 1)
ACS Medicinal Chemistry Letters     Hybrid Journal   (Followers: 46)
Acta Bio Medica     Full-text available via subscription   (Followers: 2)
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Acta Bioquimica Clinica Latinoamericana     Open Access   (Followers: 1)
Acta Científica Estudiantil     Open Access  
Acta Facultatis Medicae Naissensis     Open Access  
Acta Herediana     Open Access  
Acta Informatica Medica     Open Access  
Acta Medica (Hradec Králové)     Open Access  
Acta Medica Bulgarica     Open Access  
Acta Medica Colombiana     Open Access   (Followers: 1)
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Acta Scientiarum. Health Sciences     Open Access   (Followers: 2)
Acupuncture & Electro-Therapeutics Research     Full-text available via subscription   (Followers: 6)
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Addiction Science & Clinical Practice     Open Access   (Followers: 8)
Addictive Behaviors Reports     Open Access   (Followers: 9)
Adıyaman Üniversitesi Sağlık Bilimleri Dergisi / Health Sciences Journal of Adıyaman University     Open Access   (Followers: 1)
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Advanced Biomedical Research     Open Access  
Advanced Health Care Technologies     Open Access   (Followers: 8)
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Advances in Bioscience and Clinical Medicine     Open Access   (Followers: 7)
Advances in Clinical Chemistry     Full-text available via subscription   (Followers: 26)
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Advances in Molecular Oncology     Open Access   (Followers: 2)
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Advances in Parkinson's Disease     Open Access  
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Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 20)
Advances in Regenerative Medicine     Open Access   (Followers: 3)
Advances in Skeletal Muscle Function Assessment     Open Access  
Advances in Therapy     Hybrid Journal   (Followers: 5)
Advances in Veterinary Science and Comparative Medicine     Full-text available via subscription   (Followers: 15)
Advances in Virus Research     Full-text available via subscription   (Followers: 6)
Advances in Wound Care     Hybrid Journal   (Followers: 12)
Aerospace Medicine and Human Performance     Full-text available via subscription   (Followers: 13)
African Health Sciences     Open Access   (Followers: 3)
African Journal of Biomedical Research     Open Access   (Followers: 1)
African Journal of Clinical and Experimental Microbiology     Open Access   (Followers: 2)
African Journal of Laboratory Medicine     Open Access   (Followers: 2)
African Journal of Medical and Health Sciences     Open Access   (Followers: 3)
African Journal of Thoracic and Critical Care Medicine     Open Access  
African Journal of Trauma     Open Access   (Followers: 1)
Afrimedic Journal     Open Access   (Followers: 2)
Aggiornamenti CIO     Hybrid Journal   (Followers: 1)
AIDS Research and Human Retroviruses     Hybrid Journal   (Followers: 9)
AJOB Primary Research     Partially Free   (Followers: 3)
AJSP: Reviews & Reports     Hybrid Journal  
Aktuelle Ernährungsmedizin     Hybrid Journal   (Followers: 4)
Al-Azhar Assiut Medical Journal     Open Access   (Followers: 2)
ALERTA : Revista Científica del Instituto Nacional de Salud     Open Access  
Alexandria Journal of Medicine     Open Access   (Followers: 1)
Allgemeine Homöopathische Zeitung     Hybrid Journal   (Followers: 4)
Alpha Omegan     Full-text available via subscription  
ALTEX : Alternatives to Animal Experimentation     Open Access   (Followers: 2)
Althea Medical Journal     Open Access   (Followers: 2)
American Journal of Biomedical Engineering     Open Access   (Followers: 14)
American Journal of Biomedical Research     Open Access   (Followers: 2)
American Journal of Biomedicine     Full-text available via subscription   (Followers: 7)
American Journal of Chinese Medicine, The     Hybrid Journal   (Followers: 4)
American Journal of Clinical Medicine Research     Open Access   (Followers: 8)
American Journal of Family Therapy     Hybrid Journal   (Followers: 10)
American Journal of Law & Medicine     Full-text available via subscription   (Followers: 11)
American Journal of Lifestyle Medicine     Hybrid Journal   (Followers: 5)
American Journal of Managed Care     Full-text available via subscription   (Followers: 12)
American Journal of Medical Case Reports     Open Access   (Followers: 1)
American Journal of Medical Sciences and Medicine     Open Access   (Followers: 4)
American Journal of Medicine     Hybrid Journal   (Followers: 50)
American Journal of Medicine and Medical Sciences     Open Access   (Followers: 1)
American Journal of Medicine Studies     Open Access   (Followers: 2)
American Journal of Medicine Supplements     Full-text available via subscription   (Followers: 3)
American Journal of the Medical Sciences     Hybrid Journal   (Followers: 12)
American Journal on Addictions     Hybrid Journal   (Followers: 10)
American medical news     Free   (Followers: 3)
American Medical Writers Association Journal     Full-text available via subscription   (Followers: 5)
Amyloid: The Journal of Protein Folding Disorders     Hybrid Journal   (Followers: 5)
Anales de la Facultad de Medicina     Open Access  
Anales de la Facultad de Medicina, Universidad de la República, Uruguay     Open Access  
Anales del Sistema Sanitario de Navarra     Open Access   (Followers: 1)
Analgesia & Resuscitation : Current Research     Hybrid Journal   (Followers: 6)
Anatolian Clinic the Journal of Medical Sciences     Open Access  
Anatomica Medical Journal     Open Access  
Anatomical Science International     Hybrid Journal   (Followers: 3)
Anatomical Sciences Education     Hybrid Journal   (Followers: 1)
Anatomy     Open Access   (Followers: 2)
Anatomy Research International     Open Access   (Followers: 3)
Angewandte Schmerztherapie und Palliativmedizin     Hybrid Journal  
Angiogenesis     Hybrid Journal   (Followers: 3)
Ankara Medical Journal     Open Access   (Followers: 2)
Ankara Üniversitesi Tıp Fakültesi Mecmuası     Open Access  
Annales de Pathologie     Full-text available via subscription  
Annales des Sciences de la Santé     Open Access  
Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale     Full-text available via subscription   (Followers: 3)
Annals of African Medicine     Open Access   (Followers: 2)
Annals of Anatomy - Anatomischer Anzeiger     Hybrid Journal   (Followers: 3)
Annals of Bioanthropology     Open Access   (Followers: 5)
Annals of Biomedical Engineering     Hybrid Journal   (Followers: 18)
Annals of Biomedical Sciences     Full-text available via subscription   (Followers: 4)
Annals of Clinical Hypertension     Open Access  
Annals of Clinical Microbiology and Antimicrobials     Open Access   (Followers: 12)
Annals of Family Medicine     Open Access   (Followers: 14)
Annals of Health Research     Open Access   (Followers: 1)
Annals of Ibadan Postgraduate Medicine     Open Access  
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Medicine     Hybrid Journal   (Followers: 12)
Annals of Medicine and Surgery     Open Access   (Followers: 7)
Annals of Microbiology     Hybrid Journal   (Followers: 11)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Rehabilitation Medicine     Open Access  
Annals of Saudi Medicine     Open Access  
Annals of the New York Academy of Sciences     Hybrid Journal   (Followers: 5)
Annals of The Royal College of Surgeons of England     Full-text available via subscription   (Followers: 3)
Annual Reports in Medicinal Chemistry     Full-text available via subscription   (Followers: 7)
Annual Reports on NMR Spectroscopy     Full-text available via subscription   (Followers: 5)
Annual Review of Medicine     Full-text available via subscription   (Followers: 17)
Anthropological Review     Open Access   (Followers: 23)
Anthropologie et santé     Open Access   (Followers: 5)
Antibiotics     Open Access   (Followers: 9)
Antibodies     Open Access   (Followers: 2)
Antibody Technology Journal     Open Access   (Followers: 1)
Antibody Therapeutics     Open Access  
Anuradhapura Medical Journal     Open Access  
Anwer Khan Modern Medical College Journal     Open Access   (Followers: 2)
Apmis     Hybrid Journal   (Followers: 1)
Apparence(s)     Open Access   (Followers: 1)
Applied Clinical Informatics     Hybrid Journal   (Followers: 3)
Applied Clinical Research, Clinical Trials and Regulatory Affairs     Hybrid Journal   (Followers: 2)
Applied Medical Informatics     Open Access   (Followers: 13)
Arab Journal of Nephrology and Transplantation     Open Access   (Followers: 1)
Archive of Clinical Medicine     Open Access   (Followers: 1)
Archive of Community Health     Open Access   (Followers: 1)
Archives Medical Review Journal / Arşiv Kaynak Tarama Dergisi     Open Access  
Archives of Asthma, Allergy and Immunology     Open Access  
Archives of Medical and Biomedical Research     Open Access   (Followers: 3)
Archives of Medical Laboratory Sciences     Open Access   (Followers: 1)
Archives of Medicine and Health Sciences     Open Access   (Followers: 4)
Archives of Medicine and Surgery     Open Access  
Archives of Trauma Research     Open Access   (Followers: 3)
Archivos de Medicina (Manizales)     Open Access  
ArgoSpine News & Journal     Hybrid Journal  
Arquivos Brasileiros de Oftalmologia     Open Access   (Followers: 1)
Arquivos de Ciências da Saúde     Open Access  
Arquivos de Medicina     Open Access  
Ars Medica : Revista de Ciencias Médicas     Open Access  
ARS Medica Tomitana     Open Access   (Followers: 1)
Art Therapy: Journal of the American Art Therapy Association     Full-text available via subscription   (Followers: 17)
Arterial Hypertension     Open Access   (Followers: 1)
Artificial Intelligence in Medicine     Hybrid Journal   (Followers: 17)
Artificial Organs     Hybrid Journal   (Followers: 1)
ASHA Leader     Open Access  
Asia Pacific Family Medicine     Open Access   (Followers: 1)
Asia Pacific Journal of Clinical Nutrition     Full-text available via subscription   (Followers: 12)
Asia Pacific Journal of Clinical Trials : Nervous System Diseases     Open Access  
Asian Bioethics Review     Full-text available via subscription   (Followers: 3)
Asian Biomedicine     Open Access   (Followers: 2)
Asian Journal of Cell Biology     Open Access   (Followers: 5)
Asian Journal of Health     Open Access   (Followers: 3)
Asian Journal of Medical and Biological Research     Open Access   (Followers: 4)
Asian Journal of Medical and Pharmaceutical Researches     Open Access   (Followers: 2)
Asian Journal of Medical Sciences     Open Access   (Followers: 2)
Asian Journal of Scientific Research     Open Access   (Followers: 3)
Asian Journal of Transfusion Science     Open Access   (Followers: 1)
Asian Medicine     Hybrid Journal   (Followers: 5)
Asian Pacific Journal of Cancer Prevention     Open Access  
ASPIRATOR : Journal of Vector-borne Disease Studies     Open Access  
Astrocyte     Open Access  
Atención Familiar     Open Access  
Atención Primaria     Open Access   (Followers: 1)
Atti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche     Open Access  
Audiology - Communication Research     Open Access   (Followers: 10)
Auris Nasus Larynx     Full-text available via subscription  
Australian Coeliac     Full-text available via subscription   (Followers: 1)
Australian Family Physician     Full-text available via subscription   (Followers: 3)
Australian Journal of Medical Science     Full-text available via subscription   (Followers: 1)

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Acta Medica Colombiana
Number of Followers: 1  

  This is an Open Access Journal Open Access journal
ISSN (Print) 0120-2448
Published by SciELO Homepage  [737 journals]
  • Dr. Darío Maldonado Gómez 1936-2019

    •  
  • Acta Medica Colombiana new format

    •  
  • Progression of cognitive impairment and its relation to modifiable risk
           factors in a cohort of adults

    • Abstract: Resumen Un estudio de corte transversal realizado entre 2012-2014 en adultos autónomos de Bogotá, mostró una prevalencia de 23% de demencia, encontrándose asociada con baja escolaridad, edad avanzada e hipertensión arterial. La relación de estos factores de riesgo con la progresión del dete rioro cognitivo no ha sido estudiada en nuestra población. Objetivo: evaluar la asociación entre factores de riesgo cardiometabólicos o sociales con la progresión a deterioro cognitivo leve (DCL) o demencia, en adultos autónomos de Bogotá. Material y métodos: una cohorte de sujetos normales y con DCL, del estudio de 2012-2014, se revaluó aplicándose el protocolo neuropsiquiátrico y neuropsicológico del estudio anterior. Se realizaron análisis de correspondencia múltiple y de regresión logística. Resultados: se revaluaron 215 adultos autónomos, 118 sujetos habían sido diagnosticados con cognición normal y 97 con DCL en el primer estudio; 73% fueron mujeres con edad promedio de 71(DE:7.3) años y escolaridad de 8.2 (DE: 5.4) años. Progresaron a demencia 6% de los sujetos en un tiempo de 4(DE:1) años. Un 75% de sujetos normales permaneció sin cambio y 22% progresó a DCL; mientras que 65% de sujetos con DCL no tuvo cambios y un 25% se normalizó. Progresar de normal a DCL se asoció con baja escolaridad OR=2.43 (IC95% 1.004-5.91; p=0.049) y de DCL a demencia con IMC<25 OR=6.3 (IC95% 1.26-31; p=0.025). Conclusión: tener baja escolaridad (<5 años) se asoció en los sujetos normales con un mayor riesgo de progresión a DCL, mientras que tener un IMC <25 aumentó el riesgo de progresión a demencia en los sujetos con DCL. No identificamos factores protectores en los sujetos que se nor malizaron. (Acta Med Colomb 2019; 44: 66-74). A cross-sectional study carried out between 2012-2014 in autonomous adults of Bogotá showed a 23% prevalence of dementia, being associated with low schooling, advanced age and arterial hy pertension. The relationship between these risk factors and the progression of cognitive deterioration has not been studied in our population. Objective: to evaluate the association between cardio-metabolic or social risk factors with the progression to mild cognitive impairment (MCI) or dementia, in autonomous adults of Bogotá. Material and methods: a cohort of normal subjects with MCI, from the 2012-2014 study was re-evaluated applying the neuropsychiatric and neuropsychological protocol of the previous study. Multiple correspondence and logistic regression analyzes were performed. Results: 215 autonomous adults were re-evaluated; 118 subjects had been diagnosed with normal cognition and 97 with MCI in the first study; 73% were women with an average age of 71 (SD: 7.3) years and schooling of 8.2 (SD: 5.4) years. 6% of the subjects progressed to dementia in a time of 4 (SD: 1) years. 75% of normal subjects remained unchanged and 22% progressed to MCI while 65% of subjects with MCI did not change and 25% normalized. Progressing from normal to MCI was associated with low schooling OR = 2.43 (95% CI 1.004-5.91; p = 0.049) and from MCI to dementia with BMI≤25 OR = 6.3 (IC95% 1.26-31; p = 0.025). Conclusion: having low schooling (≤5 years) was associated in normal subjects with a higher risk of progression to MCI, while having a BMI ≤25 increased the risk of progression to dementia in subjects with MCI. Protective factors in subjects who normalized were not identified. (Acta Med Colomb 2019; 44: 66-74).
       
  • Evaluation of SAME-TT2R2 score on the quality of anticoagulation
           with warfarin

    • Abstract: Resumen Introducción: la fibrilación auricular (FA) es la arritmia cardiaca más frecuente y está relacionada con eventos embólicos. La eficacia y seguridad de la warfarina en prevención del ictus depende del tiempo en rango terapéutico (TTR). Se han diseñado escalas para predecir el comportamiento del TTR al inicio de la terapia. El objetivo de este trabajo fue evaluar la capacidad predictiva y discriminativa del SAMeTT2R2 score en una población no caucásica. Material y métodos: estudio analítico de cohorte retrospectiva en pacientes con FA no valvu lar tratados con warfarina entre 2013 y 2016 en una clínica de anticoagulación. Se caracterizó la muestra sociodemográfica y clínicamente. Se definió mal control de la anticoagulación como (TTR/ PINNR<65%). Se comparó el TTR/PINNR <65% y SAMeTT2R2 <=2 versus >2 con la prueba U de Mann-Whitney y chi cuadrado. Se construyeron curvas ROC para determinar discriminación de la escala. Se evaluó cada uno de sus elementos a través de regresión logística. Resultados: se incluyeron 646 pacientes (edad media 77 años ± 8,8 años, 51,4% hombres). El TTR promedio fue 67.7% y el PINNR 63.6%. Al comparar la frecuencia de pobre control entre SAMeTT2R2 score ≤2 versus >2 con una prueba chi cuadrado, el PINNR fue significativo (p=0.004). La capacidad discriminativa de la escala para el TTR/PINNR fue baja (AUC: 0.52 y 0.54 respectivamente). No se encontró relación entre cada una de las variables que integran el SAMeTT2R2 score y el TTR/PINNR. Conclusiones: la puntuación SAMeTT2R2 no mostró buena capacidad predictiva y discriminativa en la población estudiada. La calidad de la anticoagulación es el resultado de un proceso dinámico en relación con el cumplimiento, estado de salud o enfermedad intercurrente. (Acta Med Colomb 2019; 44: 75-81). Introduction: atrial fibrillation (AF) is the most common cardiac arrhythmia and is related to embolic events. The efficacy and safety of warfarin in stroke prevention depends on the time in therapeutic range (TTR). Scales have been designed to predict the behavior of TTR at the start of therapy. The objective of this work was to evaluate the predictive and discriminative capacity of the SAMeTT2R2 score in a non-Caucasian population. Material and methods: retrospective cohort analytical study in patients with non-valvular AF treated with warfarin between 2013 and 2016 in an anticoagulation clinic. The sample was demodemographically and clinically characterized. Poor control of anticoagulation was defined as (TTR / PINNR <65%). The TTR / PINNR <65% and SAMeTT2R2 <= 2 versus> 2 were compared with the Mann-Whitney U test and chi square. ROC curves were constructed to determine scale discrimination. Each of its elements was evaluated through logistic regression. Results: 646 patients were included (mean age 77 years ± 8.8 years, 51.4% men). The average TTR was 67.7% and the PINNR 63.6%. When comparing the frequency of poor control between C. L. Sandoval-Riveros y cols. SAMeTT2R2 score ≤2 versus> 2 with a chi square test, the PINNR was significant (p = 0.004). The discriminative capacity of the scale for the TTR / PINNR was low (AUC: 0.52 and 0.54 respec tively). No relationship was found between each of the variables that constitute the SAMeTT2R2 score and the TTR / PINNR. Conclusions: the SAMeTT2R2 score did not show good predictive and discriminative capac ity in the studied population. The quality of anticoagulation is the result of a dynamic process in relation to compliance, health status or intercurrent disease. Acta Med Colomb 2019; 44: 75-81).
       
  • Quality of life in patients with Philadelphia negative chronic
           myeloproliferative neoplasms

    • Abstract: Resumen Introducción: la carga sintomática de pacientes con neoplasias mieloproliferativas crónicas Filadélfia negativas (NMC-PhN) afecta la calidad de vida (CV). Existen escalas para evaluar la magnitud de los síntomas, una de ellas, MPN-SAF-10. En nuestra región existe escasa información sobre CV de pacientes con NMC-PhN. Objetivos: estimar el puntaje de calidad de vida con la escala MPN-SAF-10 en pacientes con NMC-PhN atendidos en el Hospital de San José (Bogotá, Colombia) y explorar asociaciones entre el tiempo de tratamiento, carga de complicaciones y el efecto en la CV. Material y métodos: estudio de corte transversal analítico para evaluar CV basada en carga sintomática de pacientes con NMC-PhN del Hospital de San José (Bogotá, Colombia). Se realizó análisis descriptivo y estratificado de calidad de vida, tratamiento citorreductor y de diferentes complicaciones, así como pruebas de asociación de los puntajes de riesgo de cada enfermedad con sus respectivos puntajes de CV. Resultados: en 64 pacientes la escala MPN-SAF-10 documentó medianas de puntajes globales de CV de 3 (RIC 1-6), MPN-SAF-10 de 20 (RIC 8-32). Un 49% de los pacientes tuvo algún grado de alteración (30% moderada y 19% severa), sin diferencias entre las tres enfermedades. Los puntajes de CV no variaron entre las NMC-PhN. El tratamiento y duración del mismo no se correlacionaron con la escala de MPN-SAF-10 (hidroxiúrea r: - 0.27; ruxolitinib r: 0.12). Conclusiones: en pacientes con NMC-PhN, la evaluación de CV con la escala MPN-SAF-10 evidencia algún grado de afectación a pesar del tratamiento; ésta es útil para objetivar dicha afectación y debe implementarse en la práctica clínica. (Acta Med Colomb 2019; 44: 82-90). Introduction: the symptomatic burden of patients with Philadelphia negative chronic myelopro liferative neoplasms (NMC-PhN) affects the quality of life (QL). There are scales to evaluate the magnitude of the symptoms; one of them, MPN-SAF-10. In our region there is scarce information on QL of patients with NMC-PhN. Objectives: To estimate the quality of life score with the MPN-SAF-10 scale in patients with NMC-PhN treated at Hospital de San José (Bogotá, Colombia) and to explore associations between treatment time, complication load and the effect on the QL. Material and methods: Analytical cross-sectional study to evaluate QL based on symptomatic load of patients with NMC-PhN from Hospital de San José (Bogotá, Colombia). A descriptive and stratified analysis of quality of life, cytoreductive treatment and different complications was carried out, as well as association tests of the risk scores of each disease with their respective QL scores. Results: in 64 patients the MPN-SAF-10 scale documented medians of global QL scores of 3 (RIC 1-6), MPN-SAF-10 of 20 (RIC 8-32). 49% of the patients had some degree of alteration (30% moderate and 19% severe), without differences between the three diseases. The QL scores did not vary between the NMC-PhN. The treatment and its duration did not correlate with the MPN-SAF-10 scale (Hydroxyurea r: - 0.27, Ruxolitinib r: 0.12). Conclusions: in patients with NMC-PhN, the evaluation of QL with the MPN-SAF-10 scale shows some degree of affectation despite the treatment; this is useful to objectify this affectation and should be implemented in clinical practice. (Acta Med Colomb 2019; 44: 82-90).
       
  • Postoperative complications in patients with mitral valve surgery

    • Abstract: Resumen Objetivos: determinar las condiciones preoperatorias e intraoperatorias que aumentan el riesgo de morbilidad y mortalidad en el posoperatorio inmediato en los pacientes con cambio de válvula mitral, en la Clínica MAC San Rafael en el periodo del 2014 al 2017. Material y métodos: se realizó un estudio de casos de tipo cuantitativo, observacional descriptivo, las variables cualitativas se presentaron en frecuencias absolutas, se realizó análisis univariado de los factores predictivos de complicaciones posoperatorias utilizando el riesgo relativo e intervalo de confianza a 95%. Para las variables cuantitativas continuas y discretas se utilizaron medidas de resumen y de tendencia central, como media, mediana, desviación estándar, rango, rango intercuartil. Resultados: en el presente estudio se reportaron 24 casos de pacientes intervenidos de cambio de válvula mitral, la edad media de los pacientes fue de 58.7 ± 15.43 años; no se hallaron diferencias estadísticamente significativas en los promedios de edad entre hombres y mujeres (p= 0.99). La hipertensión arterial es una variable estadísticamente significativa p=0.03 IC.17 (1.29-223.13), por cada paciente <50 años con hipertensión arterial hay 5.6 pacientes >50 años con la misma patología. Conclusiones: las variables preoperatorias como antecedentes de hipertensión arterial y una clase funcional NYHA III, son comunes en las complicaciones de los pacientes intervenidos sobre la válvula mitral. Además los pacientes que presentaron tiempos de clampeo y cirugía mayor que la media para otros estudios presentaron infección de sitio operatorio y septicemia. (Acta Med Colomb 2019; 44: 91-95). Objectives: to determine the preoperative and intraoperative conditions that increase the risk of morbidity and mortality in the immediate postoperative period in patients with mitral valve change at the MAC San Rafael Clinic in the period from 2014 to 2017. Material and methods: a quantitative, observational descriptive case study was conducted, qualitative variables were presented in absolute frequencies, univariate analysis of predictors of postoperative complications was performed using relative risk and 95% confidence interval. For the continuous and discrete quantitative variables, summary measures and central tendency were used, such as mean, median, standard deviation, range, interquartile range. Results: in the present study, 24 cases of patients undergoing mitral valve replacement were reported, the mean age of the patients was 58.7 ± 15.43 years; no statistically significant differences were found in the average age between men and women (p = 0.99). Hypertension is a statistically significant variable p = 0.03 IC.17 (1.29-223.13), for each patient <50 years with arterial hyperten sion there are 5.6 patients> 50 years with the same pathology. Conclusions: preoperative variables such as history of arterial hypertension and a functional class NYHA III, are common in the complications of patients operated on the mitral valve. In addi tion, patients who presented clamping and surgery times greater than the average for other studies presented infection of the operative site and septicemia. (Acta Med Colomb 2019; 44: 91-95).
       
  • Myths and facts about vaccine allergy

    • Abstract: Resumen En América Latina existen varios mitos sobre las vacunas convencionales, principalmente en pacientes con alergia alimentaria. Este artículo pretende revisar algunos de los mitos existentes, sus orígenes y proponer un abordaje clínico más adecuado. Así mismo, se propone unas directri ces acerca del manejo de los pacientes alérgicos que requieren ser vacunados. Finalmente, no se debería dejar de suministrar las vacunas a los pacientes con antecedentes de alergia alimentaria, donde la mayoría de veces se requiere el concepto del médico especialista en alergología. (Acta Med Colomb 2019; 44: 96-102). In Latin America there are several myths about conventional vaccines, mainly in patients with food allergy. This article aims to review some of the existing myths, their origins and propose a more adequate clinical approach. Likewise, some guidelines about the management of allergic patients that require vaccination are proposed. Finally, in patients with a history of food allergy, where the concept of an allergy specialist is most of the time required, the supply of vaccines should not be interrupted. (Acta Med Colomb 2019; 44: 96-102).
       
  • Case reports. How to write a good quality one'

    • Abstract: Resumen Un reporte de caso es un tipo de estudio observacional que presenta detalladamente proble mas médicos de un paciente único y de características únicas. Organizan y vuelven a narrar lo que ocurrió en la historia clínica, evolución de la enfermedad, cuidados médicos instituidos y los resultados obtenidos. Son el único medio para describir eventos clínicos raros. Si bien son el nivel de evidencia más bajo, se consideran como la primera línea de evidencia. Dentro de los reportes de casos se identifican dos tipos, unos relacionados al diagnóstico, en los cuales se aborda una condición clínica nueva o presentación inusual de una enfermedad conocida. Y otro tipo, los relacionados al tratamiento donde se evidencia un enfoque terapéutico nue vo, original o mejor y la aparición de nuevos o inusuales efectos adversos. Además, estos reportes pueden ilustrar un nuevo principio, apoyar o refutar una teoría actual y así estimular la investigación. En este artículo brindamos herramientas para este fin. Incluimos información referente a aspectos éticos, listado de revistas especializadas en publicación de reportes de casos y cómo ha sido la evolución de la publicación de los reportes de casos a lo largo del tiempo. Se hace necesaria esta información para brindar al personal en formación o con poca experiencia en el tema, cuáles son las condiciones que ameritan escribir un reporte de casos y en caso de llegar a requerirlo cómo se debería escribir de una adecuada forma. (Acta Med Colomb 2019; 44: 103-110). A case report is a type of observational study that presents in detail medical problems of a single patient with unique characteristics. They organize and retell what happened in the clinical history, evolution of the disease, medical care instituted, and the results obtained. They are the only means to describe rare clinical events. Although they are the lowest level of evidence, they are considered as the first line of evidence. Within the case reports, two types are identified; some related to the diagnosis, in which a new clinical condition or unusual presentation of a known disease is addressed, and another type, those related to treatment where a new, original or better therapeutic approach is evidenced and the appearance of new or unusual adverse effects. In addition, these reports can illustrate a new principle, support or refute a current theory and thus stimulate research. In this article, tools for this purpose are provided. Information regarding ethical aspects, a list of journals specialized in the publication of case reports and how the publication of case reports has evolved over time is included. This information is necessary to provide staff in training or with little experience in the subject which are the conditions that deserve writing a case report and in case of requiring it, how should it be written in an appropriate manner. (Acta Med Colomb 2019; 44: 103-110).
       
  • Diffuse alveolar hemorrhage secondary to ANCA-associated vasculitis.
           Relapse during hemodialysis

    • Abstract: Resumen La hemorragia alveolar difusa (HAD) masiva es una complicación inusual de los pacientes con vasculitis ANCA, frecuentemente amenaza la vida y está asociada con una mortalidad de hasta el 100%. La información en la literatura acerca del tratamiento en casos refractarios y cuando el paciente se encuentra en diálisis es escasa. Se presenta el caso de un paciente con vasculitis p-ANCA con compromiso renal y pulmonar en el escenario de síndrome pulmón-riñón, con múltiples recaídas de hemorragia alveolar a pesar de tratamiento con corticoide, azatioprina, ciclofosfamida y terapia de recambio plasmático. Se instauró manejo con anticuerpo monoclonal anti CD20 e inmunoglobulina, logrando resolución del episodio de hemorragia alveolar y permaneciendo sin actividad. Se resalta la utilidad del rituximab como estrategia terapéutica en casos refractarios. (Acta Med Colomb 2019; 44: 111-114). Massive diffuse alveolar hemorrhage (DAH) is an unusual complication of patients with ANCA vasculitis that frequently threatens life and is associated with mortality up to 100%. In formation in the literature about treatment in refractory cases and when the patient is on dialysis is scarce. The case of a patient with p-ANCA vasculitis with renal and pulmonary involvement in the lung-kidney syndrome scenario, with multiple relapses of alveolar hemorrhage despite treatment with corticosteroid, azathioprine, cyclophosphamide and plasma exchange therapy is presented. Management with anti-CD20 monoclonal antibody and immunoglobulin was estab lished, achieving resolution of the episode of alveolar hemorrhage and remaining without activity. The usefulness of rituximab as a therapeutic strategy in refractory cases is highlighted. (Acta Med Colomb 2019; 44: 111-114).
       
  • Spontaneous semitendinosus rupture secondary to the use of a quinolone

    • Abstract: Resumen La ruptura espontánea de un tendón secundario al uso de una quinolona es un efecto adverso poco común, pero que con el paso de los años se ha venido documentado con mayor frecuencia. A pesar de lo anterior, aún no hay estudios clínicos que permitan aclarar su fisiopatología, qué estrategias pueden disminuir el riesgo de desarrollar una ruptura espontánea o a qué dosis de las diferentes quinolonas se aumenta el riesgo de presentar una ruptura espontánea. Adicionalmente, varías guías de práctica clínica incentivan el uso de las quinolonas como primera línea para el manejo de infecciones respiratorias o de vías urinarias sin hacer consideraciones sobre este efecto adverso. Por lo anterior, presentamos a continuación el caso de un paciente de 31 años que posterior al inicio de ciprofloxacina para el manejo de una diarrea aguda presento una ruptura espontánea del tendón del semitendinoso secundario al uso de la quinolona. (Acta Med Colomb 2019; 44: 115-118). The spontaneous rupture of a tendon secondary to the use of a quinolone is an uncommon adverse effect, but over the years has been documented more frequently. Despite this, there are still no clini cal studies to clarify its pathophysiology, nor which strategies can reduce the risk of developing a spontaneous rupture or at what dose of the different quinolones the risk of presenting a spontaneous rupture increases. In addition, several clinical practice guidelines encourage the use of quinolones as the first line for the management of respiratory or urinary tract infections without considering this adverse effect. Therefore, the case of a 31 year old patient who after the start of ciprofloxacin for the management of acute diarrhea had spontaneous semitendinosus tendon rupture secondary to the use of quinolone, is presented. (Acta Med Colomb 2019; 44: 115-118).
       
  • Peripartum cardiomyopathy. A rare but dangerous obstetric complication

    • Abstract: Resumen La miocardiopatía periparto es una patología poco frecuente que puede conllevar a una alta tasa de mortalidad por el compromiso cardiaco si no se realiza un manejo oportuno y adecuado. Debido a su presentación clínica, las similitudes con síntomas propios del embarazo y aquellos generados por la preeclampsia, se convierte en un diagnóstico de exclusión que requiere de alta sospecha clínica. Se presenta el caso clínico de una paciente de 33 años de edad con diagnóstico de preeclampsia atípica, disfunción hepática, hematológica y renal en el puerperio, quien presentó evolución car diovascular tórpida a pesar del manejo adecuado por lo cual se sospechó y objetivó el diagnóstico de miocardiopatía periparto que progresó a una falla cardiaca aguda con disfunción multiorgánica y necesidad de trasplante cardiaco. (Acta Med Colomb 2019; 44: 119-123). Peripartum cardiomyopathy is a rare pathology that can lead to a high mortality rate due to cardiac compromise if timely and adequate management is not performed. Due to its clinical presentation, the similarities with typical symptoms of pregnancy and those generated by preeclampsia, becomes a diagnosis of exclusion that requires high clinical suspicion. The clinical case of a 33-year-old patient with a diagnosis of atypical preeclampsia, hepatic, hematological and renal dysfunction in the puerperium is presented. She had a torpid cardiovascular evolution despite adequate manage ment, which led to the diagnosis and suspicion of peripartum myocardiopathy that progressed to acute heart failure with multi-organ dysfunction and need for heart transplantation. (Acta Med Colomb 2019; 44: 119-123).
       
  • Systemic sarcoidosis with affectation of a tattoo

    • Abstract: Resumen La miocardiopatía periparto es una patología poco frecuente que puede conllevar a una alta tasa de mortalidad por el compromiso cardiaco si no se realiza un manejo oportuno y adecuado. Debido a su presentación clínica, las similitudes con síntomas propios del embarazo y aquellos generados por la preeclampsia, se convierte en un diagnóstico de exclusión que requiere de alta sospecha clínica. Se presenta el caso clínico de una paciente de 33 años de edad con diagnóstico de preeclampsia atípica, disfunción hepática, hematológica y renal en el puerperio, quien presentó evolución car diovascular tórpida a pesar del manejo adecuado por lo cual se sospechó y objetivó el diagnóstico de miocardiopatía periparto que progresó a una falla cardiaca aguda con disfunción multiorgánica y necesidad de trasplante cardiaco. (Acta Med Colomb 2019; 44: 119-123). Peripartum cardiomyopathy is a rare pathology that can lead to a high mortality rate due to cardiac compromise if timely and adequate management is not performed. Due to its clinical presentation, the similarities with typical symptoms of pregnancy and those generated by preeclampsia, becomes a diagnosis of exclusion that requires high clinical suspicion. The clinical case of a 33-year-old patient with a diagnosis of atypical preeclampsia, hepatic, hematological and renal dysfunction in the puerperium is presented. She had a torpid cardiovascular evolution despite adequate manage ment, which led to the diagnosis and suspicion of peripartum myocardiopathy that progressed to acute heart failure with multi-organ dysfunction and need for heart transplantation. (Acta Med Colomb 2019; 44: 119-123).
       
  • Mesenchymal mediastinal tumor

    • Abstract: Resumen La miocardiopatía periparto es una patología poco frecuente que puede conllevar a una alta tasa de mortalidad por el compromiso cardiaco si no se realiza un manejo oportuno y adecuado. Debido a su presentación clínica, las similitudes con síntomas propios del embarazo y aquellos generados por la preeclampsia, se convierte en un diagnóstico de exclusión que requiere de alta sospecha clínica. Se presenta el caso clínico de una paciente de 33 años de edad con diagnóstico de preeclampsia atípica, disfunción hepática, hematológica y renal en el puerperio, quien presentó evolución car diovascular tórpida a pesar del manejo adecuado por lo cual se sospechó y objetivó el diagnóstico de miocardiopatía periparto que progresó a una falla cardiaca aguda con disfunción multiorgánica y necesidad de trasplante cardiaco. (Acta Med Colomb 2019; 44: 119-123). Peripartum cardiomyopathy is a rare pathology that can lead to a high mortality rate due to cardiac compromise if timely and adequate management is not performed. Due to its clinical presentation, the similarities with typical symptoms of pregnancy and those generated by preeclampsia, becomes a diagnosis of exclusion that requires high clinical suspicion. The clinical case of a 33-year-old patient with a diagnosis of atypical preeclampsia, hepatic, hematological and renal dysfunction in the puerperium is presented. She had a torpid cardiovascular evolution despite adequate manage ment, which led to the diagnosis and suspicion of peripartum myocardiopathy that progressed to acute heart failure with multi-organ dysfunction and need for heart transplantation. (Acta Med Colomb 2019; 44: 119-123).
       
  • Palleative or Palliative'

    • Abstract: Resumen La miocardiopatía periparto es una patología poco frecuente que puede conllevar a una alta tasa de mortalidad por el compromiso cardiaco si no se realiza un manejo oportuno y adecuado. Debido a su presentación clínica, las similitudes con síntomas propios del embarazo y aquellos generados por la preeclampsia, se convierte en un diagnóstico de exclusión que requiere de alta sospecha clínica. Se presenta el caso clínico de una paciente de 33 años de edad con diagnóstico de preeclampsia atípica, disfunción hepática, hematológica y renal en el puerperio, quien presentó evolución car diovascular tórpida a pesar del manejo adecuado por lo cual se sospechó y objetivó el diagnóstico de miocardiopatía periparto que progresó a una falla cardiaca aguda con disfunción multiorgánica y necesidad de trasplante cardiaco. (Acta Med Colomb 2019; 44: 119-123). Peripartum cardiomyopathy is a rare pathology that can lead to a high mortality rate due to cardiac compromise if timely and adequate management is not performed. Due to its clinical presentation, the similarities with typical symptoms of pregnancy and those generated by preeclampsia, becomes a diagnosis of exclusion that requires high clinical suspicion. The clinical case of a 33-year-old patient with a diagnosis of atypical preeclampsia, hepatic, hematological and renal dysfunction in the puerperium is presented. She had a torpid cardiovascular evolution despite adequate manage ment, which led to the diagnosis and suspicion of peripartum myocardiopathy that progressed to acute heart failure with multi-organ dysfunction and need for heart transplantation. (Acta Med Colomb 2019; 44: 119-123).
       
 
 
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