Subjects -> MEDICAL SCIENCES (Total: 8529 journals)
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MEDICAL SCIENCES (2342 journals)            First | 3 4 5 6 7 8 9 10 | Last

Showing 1201 - 1400 of 3562 Journals sorted alphabetically
Journal of Heavy Metal Toxicity and Diseases     Open Access  
Journal of Helminthology     Hybrid Journal   (Followers: 2)
Journal of Herbs Spices & Medicinal Plants     Hybrid Journal  
Journal of HIV for Clinical and Scientific Research     Open Access   (Followers: 1)
Journal of Hospital Medicine     Hybrid Journal   (Followers: 10)
Journal of Huazhong University of Science and Technology [Medical Sciences]     Hybrid Journal  
Journal of Human Hypertension     Hybrid Journal   (Followers: 3)
Journal of Human Rhythm     Open Access  
Journal of Human Transcriptome     Open Access  
Journal of Ideas in Health     Open Access  
Journal of Inflammation     Open Access   (Followers: 2)
Journal of Inflammation Research     Open Access  
Journal of Injury and Violence Research     Open Access   (Followers: 7)
Journal of Innovation in Health Informatics     Open Access   (Followers: 17)
Journal of Institute of Medicine     Open Access  
Journal of Insulin Resistance     Open Access   (Followers: 1)
Journal of Interactional Research in Communication Disorders     Hybrid Journal   (Followers: 5)
Journal of Interferon & Cytokine Research     Hybrid Journal   (Followers: 3)
Journal of International Medical Research     Open Access   (Followers: 4)
Journal of Interventional Medicine     Open Access   (Followers: 1)
Journal of Investigative Medicine     Hybrid Journal   (Followers: 3)
Journal of Islamabad Medical & Dental College     Open Access  
Journal of Istanbul Faculty of Medicine     Open Access  
Journal of Karnali Academy of Health Sciences     Open Access   (Followers: 1)
Journal of Kathmandu Medical College     Open Access   (Followers: 1)
Journal of King Abdulaziz University : Medical Sciences     Open Access   (Followers: 2)
Journal of Laboratory Medicine     Hybrid Journal   (Followers: 27)
Journal of Laryngology and Voice     Open Access   (Followers: 11)
Journal of Lasers in Medical Sciences     Open Access  
Journal of Law, Medicine & Ethics     Hybrid Journal   (Followers: 24)
Journal of Legal Medicine     Hybrid Journal   (Followers: 7)
Journal of Limb Lengthening & Reconstruction     Open Access  
Journal of Lumbini Medical College     Open Access   (Followers: 1)
Journal of Mahatma Gandhi Institute of Medical Sciences     Open Access  
Journal of Manipulative and Physiological Therapeutics     Hybrid Journal   (Followers: 6)
Journal of Manmohan Memorial Institute of Health Sciences     Open Access   (Followers: 1)
Journal of Marine Medical Society     Open Access  
Journal of Materials Science : Materials in Medicine     Hybrid Journal   (Followers: 4)
Journal of Maternal and Child Health     Open Access  
Journal of Mechanics in Medicine and Biology     Hybrid Journal  
Journal of Medical and Biological Engineering     Hybrid Journal   (Followers: 4)
Journal of Medical and Biomedical Sciences     Open Access   (Followers: 2)
Journal of Medical Case Reports     Open Access   (Followers: 1)
Journal of Medical Cases     Open Access   (Followers: 6)
Journal of Medical Colleges of PLA     Full-text available via subscription  
Journal of Medical Disorders     Open Access  
Journal of Medical Economics     Hybrid Journal   (Followers: 8)
Journal of Medical Education and Curricular Development     Open Access   (Followers: 6)
Journal of Medical Ethics     Partially Free   (Followers: 25)
Journal of Medical Ethics and History of Medicine     Open Access   (Followers: 15)
Journal of Medical Humanities     Hybrid Journal   (Followers: 21)
Journal of Medical Hypotheses and Ideas     Open Access  
Journal of Medical Imaging and Health Informatics     Full-text available via subscription   (Followers: 1)
Journal of Medical Investigation and Practice     Open Access  
Journal of Medical Laboratory and Diagnosis     Open Access  
Journal of Medical Law and Ethics     Full-text available via subscription   (Followers: 15)
Journal of Medical Microbiology     Full-text available via subscription   (Followers: 6)
Journal of Medical Sciences     Open Access  
Journal of Medical Sciences     Open Access  
Journal of Medical Screening     Hybrid Journal   (Followers: 6)
Journal of Medical Signals and Sensors     Open Access   (Followers: 3)
Journal of Medical Society     Open Access  
Journal of Medical Systems     Hybrid Journal  
Journal of Medical Toxicology     Hybrid Journal   (Followers: 6)
Journal of Medical Ultrasound     Open Access   (Followers: 2)
Journal of Medicinal Botany     Open Access  
Journal of Medicinal Chemistry     Hybrid Journal   (Followers: 197)
Journal of Medicine     Open Access   (Followers: 1)
Journal of Medicine and Biomedical Research     Open Access   (Followers: 1)
Journal of Medicine and Philosophy     Hybrid Journal   (Followers: 8)
Journal of Medicine and the Person     Hybrid Journal  
Journal of Medicine in Scientific Research     Open Access  
Journal of Medicine in the Tropics     Open Access  
Journal of Medicine Research and Development     Open Access   (Followers: 3)
Journal of Medicine, Physiology and Biophysics     Open Access   (Followers: 5)
Journal of Medicines Development Sciences     Open Access   (Followers: 1)
Journal of Mind and Medical Sciences     Open Access   (Followers: 1)
Journal of Molecular Medicine     Hybrid Journal   (Followers: 11)
Journal of Movement Disorders     Open Access   (Followers: 2)
Journal of Muscle Research and Cell Motility     Hybrid Journal   (Followers: 1)
Journal of Nanotechnology in Engineering and Medicine     Full-text available via subscription   (Followers: 6)
Journal of Natural Medicines     Hybrid Journal  
Journal of Natural Science, Biology and Medicine     Open Access   (Followers: 3)
Journal of Nature and Science of Medicine     Open Access   (Followers: 4)
Journal of Negative and No Positive Results     Open Access  
Journal of Nepalgunj Medical College     Open Access  
Journal of Neurocritical Care     Open Access  
Journal of Neurodegenerative Diseases     Open Access   (Followers: 2)
Journal of Neurorestoratology     Open Access  
Journal of Neuroscience and Neurological Disorders     Open Access  
Journal of Nobel Medical College     Open Access  
Journal of Occupational Health     Open Access  
Journal of Occupational Therapy Education     Open Access   (Followers: 9)
Journal of Ocular Biology, Diseases, and Informatics     Hybrid Journal  
Journal of Oral Biology and Craniofacial Research     Full-text available via subscription  
Journal of Oral Health and Craniofacial Science     Open Access  
Journal of Orofacial Sciences     Open Access  
Journal of Otorhinolaryngology, Hearing and Balance Medicine     Open Access   (Followers: 1)
Journal of Ovarian Research     Open Access  
Journal of Ozone Therapy     Open Access  
Journal of Palliative Medicine     Hybrid Journal   (Followers: 47)
Journal of Paramedical Sciences & Rehabilitation     Open Access  
Journal of Parkinsonism and Restless Legs Syndrome     Open Access   (Followers: 2)
Journal of Participatory Medicine     Open Access  
Journal of Patan Academy of Health Sciences     Open Access  
Journal of Pathogens     Open Access   (Followers: 1)
Journal of Patient Experience     Open Access  
Journal of Patient Safety and Risk Management     Hybrid Journal   (Followers: 1)
Journal of Patient-Centered Research and Reviews     Open Access  
Journal of Patient-Reported Outcomes     Open Access  
Journal of Periodontal Research     Hybrid Journal  
Journal of Personalized Medicine     Open Access   (Followers: 3)
Journal of Pest Science     Hybrid Journal   (Followers: 1)
Journal of Pharmaceutical Policy and Practice     Open Access   (Followers: 4)
Journal of Physiobiochemical Metabolism     Hybrid Journal   (Followers: 2)
Journal of Physiology-Paris     Hybrid Journal   (Followers: 2)
Journal of Pioneering Medical Sciences     Open Access  
Journal of Postgraduate Medicine     Open Access  
Journal of Pregnancy     Open Access   (Followers: 4)
Journal of Prevention & Intervention Community     Hybrid Journal   (Followers: 6)
Journal of Preventive Medicine and Public Health     Open Access  
Journal of Primary Prevention     Hybrid Journal   (Followers: 7)
Journal of Prosthodontic Research     Full-text available via subscription   (Followers: 1)
Journal of Prosthodontics     Hybrid Journal   (Followers: 2)
Journal of Receptor, Ligand and Channel Research     Open Access  
Journal of Regenerative Medicine     Partially Free   (Followers: 3)
Journal of Research in Medical Sciences     Open Access   (Followers: 2)
Journal of Science and Applications : Biomedicine     Open Access   (Followers: 1)
Journal of Science and Technology (Ghana)     Open Access   (Followers: 3)
Journal of Scientific Innovation in Medicine     Open Access  
Journal of Scientific Perspectives     Open Access   (Followers: 1)
Journal of Sensory Studies     Hybrid Journal   (Followers: 4)
Journal of Shaheed Suhrawardy Medical College     Open Access  
Journal of Shoulder and Elbow Arthroplasty     Open Access  
Journal of Sleep Disorders : Treatment & Care     Hybrid Journal   (Followers: 10)
Journal of South American Earth Sciences     Hybrid Journal   (Followers: 5)
Journal of Spinal Cord Medicine     Hybrid Journal   (Followers: 4)
Journal of Spinal Disorders & Techniques     Hybrid Journal   (Followers: 2)
Journal of Sports Medicine and Allied Health Sciences : Official Journal of the Ohio Athletic Trainers Association     Open Access   (Followers: 1)
Journal of Stem Cell Therapy and Transplantation     Open Access   (Followers: 1)
Journal of Stomal Therapy Australia     Full-text available via subscription  
Journal of Strength and Conditioning Research     Hybrid Journal   (Followers: 72)
Journal of Substance Use     Hybrid Journal   (Followers: 14)
Journal of Surgical Academia     Open Access   (Followers: 1)
Journal of Surgical and Clinical Research     Open Access  
Journal of Surgical Case Reports     Open Access  
Journal of Surgical Education     Full-text available via subscription   (Followers: 3)
Journal of Surgical Technique and Case Report     Open Access  
Journal of Systemic Therapies     Full-text available via subscription   (Followers: 3)
Journal of Taibah University Medical Sciences     Open Access  
Journal of Telemedicine and Telecare     Hybrid Journal   (Followers: 12)
Journal of The Academy of Clinical Microbiologists     Open Access  
Journal of the American Association for Laboratory Animal Science     Full-text available via subscription   (Followers: 7)
Journal of the American College of Certified Wound Specialists     Hybrid Journal   (Followers: 2)
Journal of the American College of Clinical Wound Specialists     Hybrid Journal   (Followers: 2)
Journal of the American Medical Directors Association     Hybrid Journal   (Followers: 6)
Journal of the American Medical Informatics Association : JAMIA     Hybrid Journal   (Followers: 35)
Journal of the American Podiatric Medical Association     Full-text available via subscription   (Followers: 7)
Journal of the Anatomical Society of India     Full-text available via subscription  
Journal of the Anus, Rectum and Colon     Open Access  
Journal of The Arab Society for Medical Research     Open Access  
Journal of the Australasian College of Nutritional and Environmental Medicine     Full-text available via subscription  
Journal of the Australasian Society of Aerospace Medicine     Open Access   (Followers: 1)
Journal of the Ceylon College of Physicians     Open Access  
Journal of the Chinese Medical Association     Open Access   (Followers: 2)
Journal of the College of Community Physicians of Sri Lanka     Open Access  
Journal of The Egyptian Public Health Association     Open Access   (Followers: 1)
Journal of the Formosan Medical Association     Open Access   (Followers: 2)
Journal of the Ghana Science Association     Full-text available via subscription   (Followers: 3)
Journal of the Grodno State Medical University     Open Access   (Followers: 1)
Journal of the History of Medicine and Allied Sciences     Hybrid Journal   (Followers: 17)
Journal of the International Society for Telemedicine and eHealth     Open Access   (Followers: 3)
Journal of the Learning Sciences     Hybrid Journal   (Followers: 17)
Journal of the Medical Library Association     Open Access   (Followers: 283)
Journal of the Medical Sciences (Berkala ilmu Kedokteran)     Open Access   (Followers: 1)
Journal of the National Medical Association     Full-text available via subscription  
Journal of the Peripheral Nervous System     Hybrid Journal   (Followers: 3)
Journal of the Postgraduate Institute of Medicine     Open Access  
Journal of the Renin-Angiotensin-Aldosterone System     Open Access   (Followers: 1)
Journal of the Royal Society of Medicine     Hybrid Journal   (Followers: 2)
Journal of the Ruhunu Clinical Society     Open Access  
Journal of the Scientific Society     Open Access   (Followers: 1)
Journal of the Siena Academy of Sciences     Open Access   (Followers: 1)
Journal of Therapeutic Ultrasound     Open Access  
Journal of Thyroid Research     Open Access   (Followers: 1)
Journal of Tissue Engineering     Open Access   (Followers: 6)
Journal of Tissue Viability     Full-text available via subscription   (Followers: 3)
Journal of Topology     Hybrid Journal   (Followers: 1)
Journal of Toxicology     Open Access   (Followers: 11)
Journal of Traditional Chinese Medical Sciences     Open Access   (Followers: 1)
Journal of Traditional Chinese Medicine     Open Access   (Followers: 4)
Journal of Transition Medicine     Open Access  
Journal of Translational Medicine     Open Access   (Followers: 4)
Journal of Ultrasonography     Open Access   (Followers: 1)
Journal of Ultrasound     Hybrid Journal   (Followers: 4)
Journal of Ultrasound in Medicine     Full-text available via subscription   (Followers: 12)
Journal of Universal College of Medical Sciences     Open Access   (Followers: 1)
Journal of University Medical & Dental College     Open Access  
Journal of University of Babylon for Pure and Applied Sciences     Open Access  
Journal of Vascular Research     Full-text available via subscription   (Followers: 2)

  First | 3 4 5 6 7 8 9 10 | Last

Similar Journals
Journal Cover
Klinische Pädiatrie
Journal Prestige (SJR): 0.275
Citation Impact (citeScore): 1
Number of Followers: 1  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 0300-8630 - ISSN (Online) 1439-3824
Published by Thieme Publishing Group Homepage  [240 journals]
  • Editorial
    • Authors: Dörgeloh; Beate B., Dutzmann, Christina M.
      Pages: 113 - 114
      Abstract: Liebe Leserinnen und Leser,das Beckwith-Wiedemann-Syndrom (BWS) ist eine meist epigenetisch bedingte Multisystemerkrankung aus der Gruppe der Krebsprädispositionssyndrome (KPS). Der klinisch sehr heterogene Phänotyp des BWS umfasst Bauchwanddefekte (Omphalocele), Makroglossie, die zu einer typischen Fazies und Ernährungsproblemen führen kann, Organomegalie, Großwuchs (Gigantismus), der sich auch einseitig präsentieren kann, neonatale Hypoglykämien und eine Prädisposition zu der Entwicklung embryonaler Tumore, überwiegend Nephroblastome und Hepatoblastome. Bedingt wird das BWS häufig durch einen molekularen Imprinting-Defekt in der chromosomalen Region 11p15.5. Dank der bemerkenswerten Fortschritte in der Humangenetik können durch neue Erkenntnisse genetischer und epigenetischer Veränderungen bei BWS regelhaft vorliegende Mosaikkonstellationen die variablen Phänotypen erklären. Damit war die Grundlage dafür geschaffen, einen Konsensus über Diagnosekriterien trotz des heterogenen Krankheitsbildes zu finden. Es war das Ziel des im März 2017 in Paris erarbeiteten ersten internationalen Konsensus-Meetings, klinische und molekulare Diagnose- und Managementempfehlungen für Patienten aus dem Kreis des neu definierten BWS Spektrums in einem gemeinsamen Statement zu formulieren 1. Anders als wir es aus anderen Bereichen des Lebens kennen, gelang den Experten die Konsensusfindung!
      Citation: Klin Padiatr 2018; 230: 113-114
      PubDate: 2018-05-09T00:00:00+01:00
      DOI: 10.1055/a-0565-3832
      Issue No: Vol. 230, No. 03 (2018)
       
  • Nachruf Prof. Dr. med Hermann Mildenberger
    • Klin Padiatr 2018; 230: 162-162
      DOI: 10.1055/s-0044-101615



      © Georg Thieme Verlag KG Stuttgart · New York

      Artikel in Thieme eJournals:
      Inhaltsverzeichnis     Volltext

      Klin Padiatr 2018; 230: 162-1622018-05-09T00:00:00+01:00
      Issue No: Vol. 230, No. 03 (2018)
       
  • Successful Treatment of a Child With Generalized Lichen Ruber Planus
    • Klin Padiatr 2018; 230: 99-101
      DOI: 10.1055/s-0043-122396



      © Georg Thieme Verlag KG Stuttgart · New York

      Artikel in Thieme eJournals:
      Inhaltsverzeichnis     Volltext

      Klin Padiatr 2018; 230: 99-1012018-03-12T00:00:00+0100
      Issue No: Vol. 230, No. 02 (2018)
       
  • Dank an die Gutachter und Gutachterinnen
    • Klin Padiatr 2018; 230: 105-105
      DOI: 10.1055/s-0044-101234



      © Georg Thieme Verlag KG Stuttgart · New York

      Artikel in Thieme eJournals:
      Inhaltsverzeichnis     Volltext

      Klin Padiatr 2018; 230: 105-1052018-03-12T00:00:00+0100
      Issue No: Vol. 230, No. 02 (2018)
       
  • Komplexe zerebrale Fehlbildungen bei einem drei-jährigen Jungen mit
           Dup(15q)Syndrom
    • Klin Padiatr
      DOI: 10.1055/a-0598-4567



      © Georg Thieme Verlag KG Stuttgart · New York

      Artikel in Thieme eJournals:
      Inhaltsverzeichnis     Volltext

      Klin Padiatr ; : -2018-05-09T00:00:00+01:00
       
  • Prevalence of Congenital CMV Infection and Antiviral Therapy in
           Very-Low-Birth-Weight Infants: Observations of the German Neonatal Network
           
    • Authors: Humberg; Alexander, Leienbach, Viola, Fortmann, Mats I., Rausch, Tanja K., Buxmann, Horst, Müller, Andreas, Herting, Egbert, Härtel, Christoph, Göpel, Wolfgang
      Abstract: Background To determine the prevalence of congenital CMV infection (cCMV) in very-low-birth-weight infants (VLBWI) and to evaluate epidemiological characteristics of VLBWI with antiviral therapy (AT).Methods CMV-specific PCR in umbilical cord tissue was performed (n=3330). Univariate analyses and logistic regression models were used to identify associations with outcome.Results 22/3330 VLBWI received AT (0.66%). 4 of these (0.12%) were PCR positive, with 2 VLBWI showing pathological screening for hearing loss. VLBWI with AT and negative PCR had significantly reduced mean birth weight (BW) and higher rates of small-for-gestational-age (SGA). Clinical sepsis, bronchopulmonary dysplasia (BPD), use of reserve antibiotics (RA) and treatment for retinopathy of prematurity were significantly increased. We further observed a higher need of transfusion of red blood cells (RBC), fresh frozen plasma and platelets. Logistic regression (controlled for gender, gestational age, SGA and BW) showed associations for AT and BPD (OR 3.4 [1.2–10.1], p=0.024), RA (OR 20.4 [4.2–98.9], p≤0.001), transfusions of RBC (OR 11.9 [1.3–105.7], p=0.026) and platelets (OR 8.7 [2.9–26.4], p≤0.001).Discussion All VLBWI with positive PCR received AT. We hypothesize from our data by assuming a postnatal aquired CMV infection in VLBWI with AT and negative PCR that VLBWI born SGA have a different risk profile.Conclusion Further prospective studies concerning postnatal transmission should take VLBWI born SGA into account and should study the impact of infection on short- and long-term complications in this supposed vulnerable group.
      Citation: Klin Padiatr ; : -
      PubDate: 2018-04-18T00:00:00+01:00
      DOI: 10.1055/a-0598-4748
       
  • Use of Palivizumab in Germany – Report from the German Synagis™
           Registry 2009 – 2016
    • Authors: Simon; Arne, Gehrmann, Susanne, Wagenpfeil, Gudrun, Wagenpfeil, Stefan
      Abstract: Background Following national recommendations, palivizumab is administered in Germany to high-risk infants to prevent hospitalizations related to Respiratory Syncytial Virus infection.Methods In this post marketing observational study (German SYNAGIS™ Registry) data on risk factors and the clinical course of children, who received at least one palivizumab injection between 2009–2016 (01 September to June 30) were entered into an internet-based data entry system by the attending physicians after informed consent.Results 63 572 immunizations were documented for 12 729 evaluable patients (EVP) from 2009 to 2016, with an average of 5.0 immunizations per patient per season. 45% of infants received more than 5 injections. The predominant primary reason for immunization was premature birth (74%). In the EVP the rate of hospitalizations with causal relationship to RSV was 0.7% (=92/12 729) or 1.2% in a worst case scenario including patients with missing RSV test. In patients with hemodynamically significant congenital heart disease as main indication, RSV-related hospitalization rate was 0.8%. Intensive care was necessary in 16.9% (median duration 3 days), mechanical ventilation in 8.0%. No death related to RSV infection was reported.Conclusion Keeping in mind the limitations of an uncontrolled prospective observational study, our results confirm the effectiveness and safety of palivizumab prophylaxis. The total number of patients with hsCHD is lower than expected. A better adjustment to the regional epidemiology would probably reduce the need for more than 5 injections.
      Citation: Klin Padiatr ; : -
      PubDate: 2018-04-16T00:00:00+01:00
      DOI: 10.1055/a-0595-7771
       
  • Spectrum of Parvovirus B19 Infection Presentations in Children with
           Underlying Hemato-oncologic Disorders: A Case Series
    • Klin Padiatr
      DOI: 10.1055/a-0594-9362



      © Georg Thieme Verlag KG Stuttgart · New York

      Artikel in Thieme eJournals:
      Inhaltsverzeichnis     Volltext

      Klin Padiatr ; : -2018-04-16T00:00:00+01:00
       
  • Fluchtwege von schwerkranken Kindern und Jugendlichen aus den ehemaligen
           Ostblockländern nach Deutschland zur Behandlung des Nierenversagens
    • Authors: Mammadova; Dilbar, Marek, Ines, Galiano, Matthias, Rascher, Wolfgang
      Abstract: Hintergrund Erhöhte Patientenmobilität und eingeschränkte Behandlungsmöglichkeiten von Kindern mit terminaler Niereninsuffizienz veranlassten Familien aus den ehemaligen Ostblockländern mit ihren Kindern zur Behandlung nach Deutschland zu fliehen.Methode In einer Fallstudie wurden Krankenakten retrospektiv analysiert. In strukturierten Interviews wurden Eltern und Patienten nach dem Fluchtweg, der Behandlung und Integration befragt.Ergebnisse Von 2003 bis 2013 kamen 8 Kinder und Jugendliche zur Behandlung eines terminalen Nierenversagens nach Erlangen. Die meisten Patienten kamen mithilfe eines Schleusers mit einem Touristenvisum. Auffallend oft gaben sie an, in der Aufregung ihre Papiere verloren zu haben. Eine Familie erhielt vom Schleuser neue Pässe mit gefälschten Namen und Geburtsdaten. Die Familien waren gezwungen, für die Flucht hohe Kosten auf sich zu nehmen, um durch die Behandlung in Deutschland das Leben ihres Kindes zu retten. Auch wenn sich die Dialysetherapie wegen eines anderen Krankheitsverständnisses oft schwierig gestaltete, war der Gesamtverlauf zufriedenstellend. Vier Patienten konnten mittlerweile erfolgreich transplantiert werden.Schlussfolgerung Diese Fallstudie zeigt neue Facetten der Patientenmobilität, die durch die bessere medizinische Versorgung in Deutschland motiviert ist und das Ziel hat, das Überleben des Kindes zu sichern. Ein ethisches Problem ergab sich dadurch, dass eine Dialysebehandlung bei Kindern mit terminaler Niereninsuffizienz die Nierentransplantation als therapeutisches Ziel impliziert. 
      Citation: Klin Padiatr ; : -
      PubDate: 2018-04-12T00:00:00+01:00
      DOI: 10.1055/s-0044-101547
       
  • Motivierende Kurzinterventionen nach Krankenhausaufenthalt bei
           Alkoholintoxikation bei Jugendlichen – Effektive Option sekundärer
           Prävention'
    • Authors: Klein; Marcus O., Hammerich, Sünje, Eggert, Paul, Ankermann, Tobias
      Abstract: In einer prospektiven, randomisierten, einfach blinden Studie wurden 48 Jugendliche zwischen 13 und 17 Jahren am Morgen nach stationärer Aufnahme mit Alkoholintoxikation mithilfe eines standardisierten Fragebogens zum bisherigen Trinkverhalten befragt. Während bei einem Teil der Jugendlichen eine psychologische Intervention (HaLT-Präventionsprojekt) erfolgte (A: n=28), wurde bei dem anderen Teil der Studienteilnehmer auf das Gespräch verzichtet (B: n=20). 6 und 12 Wochen nach dem stationären Aufenthalt wurden die Jugendlichen telefonisch zum aktuellen Trinkverhalten befragt. Insgesamt tranken 58% (n=28) der Studienteilnehmer im Untersuchungszeitraum weniger und/ oder seltener Alkohol als vor der Alkoholintoxikation. 17% (n=8) verzichteten während der 12 Wochen komplett auf den Konsum alkoholischer Getränke. 54% (n=26) der Jugendlichen behaupteten, nicht wieder betrunken gewesen zu sein. 38% (n=18) haben ihr Trinkverhalten nicht verändert und 6% (n=3) tranken mehr und/oder häufiger als zuvor Alkohol. Es gab keinen statistisch signifikanten Unterschied in der Entwicklung des Trinkverhaltens zwischen den beiden Gruppen: 58% (A) bzw. 65% (B) der Jugendlichen mit bzw. ohne Gespräch tranken nach dem Ereignis weniger und/ oder seltener (χ²=0,6269, p=0,4285). Ein Einfluss der Gespräche im Rahmen des HaLT-Präventionsprojektes bei stationär aufgenommenen Jugendlichen nach Alkoholintoxikation konnte nicht nachgewiesen werden. Weitere Untersuchungen müssen Interventionen bei Eltern und peers mit einbeziehen.
      Citation: Klin Padiatr ; : -
      PubDate: 2018-04-09T00:00:00+01:00
      DOI: 10.1055/a-0590-4726
       
  • Erhebungseinheit für seltene pädiatrische Erkrankungen in Deutschland
           (ESPED) – 25 Jahre pädiatrische Epidemiologie: Eine Bestandsaufnahme
    • Authors: Ebrahimi-Fakhari; Daniel, Zemlin, Michael, Sauer, Harald, Poryo, Martin, Graf, Norbert, Meyer, Sascha
      Abstract: Hintergrund Die Erhebungseinheit für seltene pädiatrische Erkrankungen in Deutschland (ESPED) wurde 1992 mit dem Ziel gegründet, Daten zur Inzidenzbestimmung und zum Krankheitsverlauf seltener pädiatrischer Erkrankungen zu erheben.Methoden und Fragestellung Retrospektive Analyse der von 1992–2017 durch ESPED erhobenen epidemiologischen Daten bezüglich untersuchter Krankheitsbilder und -gruppen sowie systematische Analyse sämtlicher nationaler und internationaler ESPED-Publikationen. Zudem wurden die Kriterien zur Evaluation von Surveillance-Systemen des Center of Disease Control and Prevention (CDC) auf ESPED bzgl. Einfachheit, Flexibilität, Rechtzeitigkeit, Qualität der Daten, Repräsentanz und Vollständigkeit, Akzeptanz und Stabilität angewandt.Ergebnisse Im Zeitraum 1992–2017 wurden prospektiv 96 seltene Krankheitsentitäten untersucht. Die 3 größten Krankheitsgruppen waren: Infektiologie (n=30), Neuropädiatrie (n=14) und Hämatologie/Hämostaseologie (n=10). Es wurden 337 Publikationen in Kooperation mit ESPED in nationalen und internationalen Fachzeitschriften veröffentlicht. Bei den 192 Publikationen mit Impact-Faktor (IF) betrug der mediane IF 2,587 (Range 0,032–28,409). Die höchsten IF wurden in den Bereichen Endokrinologie/Stoffwechsel (n=130; medianer IF=3,534), Infektiologie (n=83; medianer IF=3,131) und Hämatologie/Hämostaseologie (n=37; medianer IF=2,497) erzielt. Unsere Untersuchung zeigte, dass ESPED die definierten CDC-Qualitätskriterien erfüllt.Schlussfolgerung ESPED ist ein sinnvolles, qualitativ hochwertiges Instrument zur Erfassung der Inzidenz sowie zur Beschreibung klinischer Erscheinungsformen von seltenen pädiatrischen Erkrankungen. Dies spiegelt sich in Publikationen in hochkarätigen nationalen und internationalen Fachzeitschriften wider.
      Citation: Klin Padiatr ; : -
      PubDate: 2018-04-03T00:00:00+01:00
      DOI: 10.1055/a-0586-4365
       
  • Successful Surgical Removal of A Massive Iliopsoas Pseudotumor in a Boy
           With Mild Hemophilia A
    • Klin Padiatr
      DOI: 10.1055/a-0586-4514



      © Georg Thieme Verlag KG Stuttgart · New York

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      Klin Padiatr ; : -2018-03-27T00:00:00+01:00
       
  • Neonatal Listeriosis and The Importance of Body Surface Cultures
    • Klin Padiatr
      DOI: 10.1055/a-0588-5423



      © Georg Thieme Verlag KG Stuttgart · New York

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      Klin Padiatr ; : -2018-03-27T00:00:00+01:00
       
  • Transienter Pseudohypoaldosteronismus – eine wichtige
           Differenzialdiagnose des Adrenogenitalen Syndroms
    • Klin Padiatr
      DOI: 10.1055/a-0575-4068



      © Georg Thieme Verlag KG Stuttgart · New York

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      Klin Padiatr ; : -2018-03-21T00:00:00+0100
       
  • Update on Transumbilical Single-Incision Laparoscopic Assisted
           Appendectomy (TULAA) – Which Children Benefit and What are the
           Complications'
    • Authors: Dübbers; Martin, Nikolaou, Elena, Fuchs, Hans, Fischer, Janina, Alakus, Hakan, Leers, Jessica, Bruns, Christiane, Cernaianu, Grigore
      Abstract: Background Transumbilical laparoscopic-assisted appendectomy (TULAA) is fast and cost-effective since no endoloops, staplers or wound protection devices are used. We analyzed the effects of TULAA as first approach for perforated (PA) and non-perforated (NPA) appendicitis in children.Patients We performed a retrospective analysis of 181 children for whom TULAA was the first approach for appendicitis between October 2010 and March 2016. Methods Morbidity, additional laparoscopic instrument insertion (AI), conversions to open extraumbilical appendectomy (OC), and complications were evaluated.Results TULAA was initiated in 181 (87.4%) children (113 boys: 68 girls). Median age was 10.3 years (3.3–13.9 years) and BMI 16.8 kg/m2 (12.4–30.8). Appendicitis was non-perforated in 157 (86.7%) and perforated in 24 (13.3%) patients. TULAA was finalized in 142 (78.5%) patients, AI were inserted in 20 (11%) and OC were performed in 19 (10.5%) patients. Duration of surgery did not exceed 20 min for 12.8%, and 30 min for 43.6% of patients with TULAA and NPA. The rate of wound infections did not differ between procedures (TULAA 3/142 (2.1%), AI 0 (0%), OC 1/19 (5.3%), P=1.000). Further postoperative course was uneventful in 179 (98.9%) patients.Conclusion TULAA can be used as first approach for appendicitis in all children with a low rate of complications. Extracorporeal appendix stump closure can be safely achieved in the majority of children without using laparoscopic disposable devices.
      Citation: Klin Padiatr ; : -
      PubDate: 2018-03-15T00:00:00+0100
      DOI: 10.1055/s-0044-101622
       
  • Benchmarking of Four Near Infrared Spectroscopy Devices for Long Time Use
           in Neonates
    • Authors: Schneider; Anna, Hofstätter, Edda, Brandner, Johannes, Moder, Angelika, Häusler, Silke, Wald, Martin
      Abstract: Background Using near-infrared spectroscopy (NIRS) mixed tissue saturation can be calculated by measuring the oxygen saturation of oxygenated and deoxygenated erythrocytes in the tissue. Quality of the calculated value is not only dependent on the exposure of the measured values in the calculation, but also on external factors such as artifacts. Main object of this study was to determine whether and how the measurement quality of different devices varies in their long-term use in premature infants.Patients and Methods In 54 measurements, each lasting 2 hours, 4 NIRS devices were attached in pairs on the forehead of 9 cardio-respiratory stable, spontaneous breathing premature infants. Pooled meta-analysis was used to compare the correlation between regional tissue saturation to the pulse oximetry saturation per device.Results The pooled random effect of all Pearson’s correlation coefficients was 0.490 (CI95: 0.403-0.568) with the NIRO 200, 0.575 (CI95: 0.463-0.668) with the INVOS 5100c, 0.712 (CI95: 0.640-0.772) with the Fore-Sight and 0.638 (CI95: 0.554-0.709) with the SenSmart X- 100.Conclusion In this trial, a significant correlation between the tissue saturation and pulsoxymetry saturation was observed. The tremendous variation range among the measurements showed, however, that the measurement quality can be severely affected by unrecognized artifacts, after excluding other possible causes. None of the devices had reliable artifact detection for long-term measurements in very small premature infants. Key words: Near-Infrared-Spectroscopy, premature infants, Benchmark Test, Long-term measurements
      Citation: Klin Padiatr ; : -
      PubDate: 2018-03-14T00:00:00+0100
      DOI: 10.1055/s-0044-102256
       
  • Purpura fulminans – It’s Not Always Sepsis
    • Klin Padiatr
      DOI: 10.1055/s-0044-100620



      © Georg Thieme Verlag KG Stuttgart · New York

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      Klin Padiatr ; : -2018-01-30T00:00:00+0100
       
  • Intrathekale Nursinersen-Therapie bei Kindern mit Spinaler Muskelatrophie
           und Wirbelsäulendeformitäten
    • Klin Padiatr
      DOI: 10.1055/s-0044-100621



      © Georg Thieme Verlag KG Stuttgart · New York

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      Klin Padiatr ; : -2018-01-29T00:00:00+0100
       
 
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