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Showing 1 - 200 of 3562 Journals sorted alphabetically
16 de Abril     Open Access  
AADE in Practice     Hybrid Journal   (Followers: 4)
ABCS Health Sciences     Open Access   (Followers: 1)
Abia State University Medical Students' Association Journal     Full-text available via subscription  
ACIMED     Open Access   (Followers: 1)
ACS Medicinal Chemistry Letters     Full-text available via subscription   (Followers: 39)
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Acta Medica Peruana     Open Access   (Followers: 2)
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Acta Scientiarum. Health Sciences     Open Access  
Acupuncture & Electro-Therapeutics Research     Full-text available via subscription   (Followers: 2)
Addiction Science & Clinical Practice     Open Access   (Followers: 7)
Addictive Behaviors Reports     Open Access   (Followers: 6)
Advanced Health Care Technologies     Open Access   (Followers: 4)
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Advances in Parkinson's Disease     Open Access  
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Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 20)
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Advances in Virus Research     Full-text available via subscription   (Followers: 5)
Advances in Wound Care     Hybrid Journal   (Followers: 10)
African Health Sciences     Open Access   (Followers: 2)
African Journal of Biomedical Research     Open Access  
African Journal of Clinical and Experimental Microbiology     Open Access   (Followers: 1)
African Journal of Laboratory Medicine     Open Access   (Followers: 2)
African Journal of Medical and Health Sciences     Open Access   (Followers: 2)
African Journal of Trauma     Open Access  
Afrimedic Journal     Open Access   (Followers: 2)
Aggiornamenti CIO     Hybrid Journal   (Followers: 1)
AIDS Research and Human Retroviruses     Hybrid Journal   (Followers: 8)
AJOB Primary Research     Partially Free   (Followers: 3)
Aktuelle Ernährungsmedizin     Hybrid Journal   (Followers: 4)
Al-Azhar Assiut Medical Journal     Open Access  
Alexandria Journal of Medicine     Open Access   (Followers: 1)
Allgemeine Homöopathische Zeitung     Hybrid Journal   (Followers: 2)
Alpha Omegan     Full-text available via subscription  
ALTEX : Alternatives to Animal Experimentation     Open Access   (Followers: 3)
American Journal of Biomedical Engineering     Open Access   (Followers: 11)
American Journal of Biomedical Research     Open Access   (Followers: 2)
American Journal of Biomedicine     Full-text available via subscription   (Followers: 6)
American Journal of Chinese Medicine, The     Hybrid Journal   (Followers: 5)
American Journal of Clinical Medicine Research     Open Access   (Followers: 5)
American Journal of Family Therapy     Hybrid Journal   (Followers: 11)
American Journal of Law & Medicine     Full-text available via subscription   (Followers: 12)
American Journal of Lifestyle Medicine     Hybrid Journal   (Followers: 5)
American Journal of Managed Care     Full-text available via subscription   (Followers: 11)
American Journal of Medical Case Reports     Open Access   (Followers: 1)
American Journal of Medical Sciences and Medicine     Open Access   (Followers: 1)
American Journal of Medicine     Hybrid Journal   (Followers: 46)
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American Journal of Medicine Studies     Open Access  
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American Journal of the Medical Sciences     Hybrid Journal   (Followers: 12)
American Journal on Addictions     Hybrid Journal   (Followers: 9)
American Medical Journal     Open Access   (Followers: 4)
American medical news     Free   (Followers: 3)
American Medical Writers Association Journal     Full-text available via subscription   (Followers: 2)
Amyloid: The Journal of Protein Folding Disorders     Hybrid Journal   (Followers: 4)
Anales de la Facultad de Medicina     Open Access  
Anales de la Facultad de Medicina, Universidad de la República, Uruguay     Open Access  
Anales del Sistema Sanitario de Navarra     Open Access   (Followers: 1)
Analgesia & Resuscitation : Current Research     Hybrid Journal   (Followers: 3)
Anatomical Science International     Hybrid Journal   (Followers: 2)
Anatomical Sciences Education     Hybrid Journal   (Followers: 1)
Anatomy Research International     Open Access   (Followers: 2)
Angewandte Schmerztherapie und Palliativmedizin     Hybrid Journal  
Angiogenesis     Hybrid Journal   (Followers: 3)
Annales de Pathologie     Full-text available via subscription  
Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale     Full-text available via subscription   (Followers: 3)
Annals of African Medicine     Open Access   (Followers: 1)
Annals of Anatomy - Anatomischer Anzeiger     Hybrid Journal   (Followers: 2)
Annals of Bioanthropology     Open Access   (Followers: 3)
Annals of Biomedical Engineering     Hybrid Journal   (Followers: 18)
Annals of Biomedical Sciences     Full-text available via subscription   (Followers: 3)
Annals of Clinical Microbiology and Antimicrobials     Open Access   (Followers: 8)
Annals of Family Medicine     Open Access   (Followers: 12)
Annals of Fundeni Hospital     Open Access   (Followers: 1)
Annals of Ibadan Postgraduate Medicine     Open Access  
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Medicine     Hybrid Journal   (Followers: 12)
Annals of Medicine and Surgery     Open Access   (Followers: 5)
Annals of Microbiology     Hybrid Journal   (Followers: 10)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Saudi Medicine     Open Access  
Annals of the New York Academy of Sciences     Hybrid Journal   (Followers: 5)
Annals of The Royal College of Surgeons of England     Full-text available via subscription   (Followers: 3)
Annual Reports in Medicinal Chemistry     Full-text available via subscription   (Followers: 7)
Annual Reports on NMR Spectroscopy     Full-text available via subscription   (Followers: 4)
Annual Review of Medicine     Full-text available via subscription   (Followers: 18)
Anthropological Review     Open Access   (Followers: 24)
Anthropologie et santé     Open Access   (Followers: 5)
Antibiotics     Open Access   (Followers: 9)
Antibodies     Open Access   (Followers: 2)
Antibody Technology Journal     Open Access   (Followers: 1)
Anuradhapura Medical Journal     Open Access  
Anwer Khan Modern Medical College Journal     Open Access   (Followers: 2)
Apmis     Hybrid Journal   (Followers: 1)
Apparence(s)     Open Access   (Followers: 1)
Applied Clinical Informatics     Hybrid Journal   (Followers: 2)
Applied Medical Informatics     Open Access   (Followers: 11)
Arab Journal of Nephrology and Transplantation     Open Access   (Followers: 1)
Arak Medical University Journal     Open Access  
Archive of Clinical Medicine     Open Access   (Followers: 1)
Archive of Community Health     Open Access  
Archives of Biomedical Sciences     Open Access   (Followers: 7)
Archives of Medical and Biomedical Research     Open Access   (Followers: 3)
Archives of Medical Laboratory Sciences     Open Access   (Followers: 1)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Archives of Trauma Research     Open Access   (Followers: 2)
Archivos de Medicina (Manizales)     Open Access  
ArgoSpine News & Journal     Hybrid Journal  
Arquivos Brasileiros de Oftalmologia     Open Access  
Arquivos de Ciências da Saúde     Open Access  
Arquivos de Medicina     Open Access  
ARS Medica Tomitana     Open Access   (Followers: 1)
Art Therapy: Journal of the American Art Therapy Association     Full-text available via subscription   (Followers: 10)
Arterial Hypertension     Open Access  
Artificial Intelligence in Medicine     Hybrid Journal   (Followers: 12)
Artificial Organs     Hybrid Journal   (Followers: 1)
Asia Pacific Family Medicine     Open Access  
Asia Pacific Journal of Clinical Nutrition     Full-text available via subscription   (Followers: 9)
Asia Pacific Journal of Clinical Trials : Nervous System Diseases     Open Access  
Asian Bioethics Review     Full-text available via subscription   (Followers: 2)
Asian Journal of Cell Biology     Open Access   (Followers: 6)
Asian Journal of Health     Open Access   (Followers: 3)
Asian Journal of Medical and Biological Research     Open Access   (Followers: 2)
Asian Journal of Medical and Pharmaceutical Researches     Open Access   (Followers: 1)
Asian Journal of Medical Sciences     Open Access   (Followers: 1)
Asian Journal of Scientific Research     Open Access   (Followers: 2)
Asian Journal of Transfusion Science     Open Access   (Followers: 2)
Asian Medicine     Hybrid Journal   (Followers: 4)
ASPIRATOR : Journal of Vector-borne Disease Studies     Open Access  
Astrocyte     Open Access  
Atención Familiar     Open Access  
Atención Primaria     Open Access   (Followers: 1)
Audiology - Communication Research     Open Access   (Followers: 8)
Auris Nasus Larynx     Full-text available via subscription  
Australian Coeliac     Full-text available via subscription   (Followers: 2)
Australian Family Physician     Full-text available via subscription   (Followers: 3)
Australian Journal of Medical Science     Full-text available via subscription   (Followers: 1)
Autopsy and Case Reports     Open Access  
Aviation, Space, and Environmental Medicine     Full-text available via subscription   (Followers: 10)
Avicenna     Open Access   (Followers: 2)
Avicenna Journal of Medicine     Open Access   (Followers: 1)
Bangabandhu Sheikh Mujib Medical University Journal     Open Access   (Followers: 1)
Bangladesh Journal of Anatomy     Open Access   (Followers: 1)
Bangladesh Journal of Bioethics     Open Access  
Bangladesh Journal of Medical Biochemistry     Open Access   (Followers: 3)
Bangladesh Journal of Medical Education     Open Access   (Followers: 2)
Bangladesh Journal of Medical Microbiology     Open Access   (Followers: 3)
Bangladesh Journal of Medical Physics     Open Access  
Bangladesh Journal of Medical Science     Open Access  
Bangladesh Journal of Medicine     Open Access   (Followers: 1)
Bangladesh Journal of Physiology and Pharmacology     Open Access  
Bangladesh Journal of Scientific Research     Open Access   (Followers: 2)
Bangladesh Medical Journal     Open Access  
Bangladesh Medical Journal Khulna     Open Access  
Bangladesh Medical Research Council Bulletin     Open Access  
Basal Ganglia     Hybrid Journal  
Basic Sciences of Medicine     Open Access   (Followers: 2)
BBA Clinical     Open Access  
BC Medical Journal     Free  
Benha Medical Journal     Open Access  
Bijblijven     Hybrid Journal  
Bijzijn     Hybrid Journal   (Followers: 2)
Bijzijn XL     Hybrid Journal   (Followers: 1)
Bio-Algorithms and Med-Systems     Hybrid Journal   (Followers: 1)
BioDiscovery     Open Access   (Followers: 2)
Bioelectromagnetics     Hybrid Journal   (Followers: 1)
Bioengineering & Translational Medicine     Open Access  
Bioethics     Hybrid Journal   (Followers: 14)
Bioethics Research Notes     Full-text available via subscription   (Followers: 14)
Biologics in Therapy     Open Access  
Biology of Sex Differences     Open Access   (Followers: 3)

        1 2 3 4 5 6 7 8 | Last

Journal Cover American Journal on Addictions
  [SJR: 0.843]   [H-I: 57]   [9 followers]  Follow
   Hybrid Journal Hybrid journal (It can contain Open Access articles)
   ISSN (Print) 1055-0496 - ISSN (Online) 1521-0391
   Published by John Wiley and Sons Homepage  [1589 journals]
  • Issue Information
    • PubDate: 2017-11-22T07:06:18.026614-05:
      DOI: 10.1111/ajad.12645
  • Issue Information ‐ Editorial Board
    • First page: 766
      PubDate: 2017-11-22T07:06:19.257007-05:
      DOI: 10.1111/ajad.12646
  • Issue Information ‐ ToC
    • First page: 767
      PubDate: 2017-11-22T07:06:18.20589-05:0
      DOI: 10.1111/ajad.12647
  • Save the Date 28th
    • First page: 769
      PubDate: 2017-11-22T07:06:18.160627-05:
      DOI: 10.1111/ajad.12648
  • Call for Review Papers
    • First page: 770
      PubDate: 2017-11-22T07:06:21.416376-05:
      DOI: 10.1111/ajad.12649
  • Call for Special Issue Papers
    • First page: 771
      PubDate: 2017-11-22T07:06:20.400095-05:
      DOI: 10.1111/ajad.12650
  • Reports of adverse health effects related to synthetic cannabinoid use in
           New York State
    • Authors: Eleni A. Papadopoulos; Karen R. Cummings, Jeanna M. Marraffa, Kenneth M. Aldous, Lingyun Li, Nina Ahmad
      First page: 772
      Abstract: Background/ObjectivesWe assessed synthetic cannabinoid (SC) outbreaks from 2011–2012 and 2015.MethodsThe National Poison Data System was utilized to collect reports of SC adverse effects in New York State from 2011–2012 and 2015 (N = 713).ResultsCases from 2015 were more likely to be admitted to intensive care units and had different symptoms than those in 2011–2012. We identified two new SC structural classes from 2015 samples.Discussion/ConclusionsThe 2015 outbreak was associated with more severe SC‐related illnesses than in 2011–2012.Scientific SignificanceNew SC compounds may pose a different or more severe risk than those previously identified. (Am J Addict 2017;XX:1–4)
      PubDate: 2017-11-06T01:15:26.995228-05:
      DOI: 10.1111/ajad.12636
  • Either at left or right, both high and low frequency rTMS of dorsolateral
           prefrontal cortex decreases cue induced craving for methamphetamine
    • Authors: Qingming Liu; Ying Shen, Xinyu Cao, Yongqiang Li, Yijiang Chen, Wei Yang, Ti-Fei Yuan
      First page: 776
      Abstract: Background and ObjectivesThe study is to investigate if left or right dorsolateral prefrontal cortex is important in modulating the craving to drug related cues.MethodsThe present investigation examined different combinations between left/right and high/low frequency rTMS on cue induced craving to methamphetamine, with active sham rTMS on P3 region on a total of 50 subjects.ResultsThe results showed that either at left or right side, both high and low frequency rTMS are effective in decreasing the cue induced craving to methamphetamine.Discussion and ConclusionsIn conclusion, bilateral frontal hemispheres are effective in modulating the cue induced craving to methamphetamine with rTMS.Scientific SignificanceTMS targeting prefrontal cortex is effective for craving modulation; however the mechanism is more than potentiation or depression of single brain region. (Am J Addict 2017;XX:1–4)
      PubDate: 2017-11-14T00:52:49.723048-05:
      DOI: 10.1111/ajad.12638
  • Factors associated with attrition in substance using patients enrolled in
           an intensive outpatient program
    • Authors: James Mckowen; Nicholas Carrellas, Courtney Zulauf, Emin Nalan Ward, Ronna Fried, Timothy Wilens
      First page: 780
      Abstract: Background and ObjectivesData suggest individuals with substance use disorders (SUD) have high rates of attrition from treatment and exhibit impairments on measures of executive functioning (EF). The primary aim of this pilot study was to investigate if EF is associated with attrition from a 1 month intensive outpatient program (IOP) for SUD, and examine the feasibility of implementing the project.MethodsBaseline neurocognitive functioning was assessed by the Cambridge Neuropsychological Test Automated Battery (CANTAB) and the self‐reported Behavior Rating Inventory of Executive Functioning (BRIEF‐A) questionnaire.ResultsThirty subjects enrolled in the pilot study: including 20 “completers” (age 39.5 ± 13.1 years) and 10 “drop‐outs” who discontinued the IOP prior to completion (age 32 ± 11.1 years). IOP drop‐out was associated with earlier age of substance use onset (all p‐values
      PubDate: 2017-09-18T05:00:33.338516-05:
      DOI: 10.1111/ajad.12619
  • Transcranial magnetic stimulation of the dorsal lateral prefrontal cortex
           inhibits medial orbitofrontal activity in smokers
    • Authors: Xingbao Li; Gregory L. Sahlem, Bashar W. Badran, Lisa M. McTeague, Colleen A. Hanlon, Karen. J. Hartwell, Scott Henderson, Mark S. George
      First page: 788
      Abstract: Background and ObjectiveSeveral studies have shown that repetitive transcranial magnetic stimulation (rTMS), applied to the dorsolateral prefrontal cortex (DLPFC), can reduce cue‐elicited craving in smokers. Currently, the mechanism of this effect is unknown. We used functional magnetic resonance imaging (fMRI) to explore the effect of a single treatment of rTMS on cortical and sub‐cortical neural activity in non‐treatment seeking nicotine‐dependent participants.MethodsWe conducted a randomized, counterbalanced, crossover trial in which participants attended two experimental visits separated by at least 1 week. On the first visit, participants received either active, or sham rTMS (10 Hz, 5 s‐on, 10 s‐off, 100% motor threshold, 3,000 pulses) over the left DLPFC, and on the second visit they received the opposite condition (active or sham). Cue craving fMRI scans were completed before and after each rTMS session.ResultsA total of 11 non‐treatment seeking nicotine‐dependent cigarette smokers were enrolled in the study [six female, average age 39.7 ± 13.2, average cigarettes per day 17.3 ± 5.9]. Active rTMS decreased activity in the contralateral medial orbitofrontal cortex (mOFC) and ipsilateral nucleus accumbens (NAc) compared to sham rTMS.ConclusionsThis preliminary data suggests that one session of rTMS applied to the DLPFC decreases brain activity in the NAc and mOFC in smokers.Scientific SignificancerTMS may exert its anti‐craving effect by decreasing activity in the NAc and mOFC in smokers. Despite a small sample size, these findings warrant future rTMS/fMRI studies in addictions. (Am J Addict 2017;XX:1–7)
      PubDate: 2017-09-12T06:35:34.701178-05:
      DOI: 10.1111/ajad.12621
  • Nabilone pharmacotherapy for cannabis dependence: A randomized, controlled
           pilot study
    • Authors: Kevin P. Hill; Matthew D. Palastro, Staci A. Gruber, Garrett M. Fitzmaurice, Shelly F. Greenfield, Scott E. Lukas, Roger D. Weiss
      First page: 795
      Abstract: Background and ObjectivesWe assessed the safety, tolerability, and preliminary efficacy of nabilone, a cannabinoid agonist, to treat cannabis dependence.MethodsEighteen adults with DSM‐IV cannabis dependence were randomized to receive either 2 mg/day of nabilone (n = 10) or placebo (n = 8) for 10 weeks in addition to medication management. Twelve participants, six in each group, completed treatment. The safety and tolerability of nabilone was assessed at each visit. Any side effects from nabilone or the placebo were documented. Cannabis use outcomes were assessed via self‐report of days of use and twice‐weekly urine cannabinoid tests; secondary outcomes included cannabis craving and anxiety.ResultsWe assessed safety and tolerability at each study visit. A total of eight adverse events, all mild or moderate, were reported in two participants in the nabilone group, and six events were reported in four participants in the placebo group during study treatment. A total of eight adverse events were reported in two participants in the nabilone group and six events were reported in four participants in the placebo group during study treatment. All reported adverse events were rated mild‐to‐moderate. There were no side effects deemed serious enough to be classified as an FDA‐defined serious adverse event. In general, participants in both groups reported reduced cannabis use according to self‐report over the course of the study, although these reductions were not statistically discernible. Moreover, there was no difference in cannabis use between the nabilone group and the placebo group as measured by self‐report.Discussion and ConclusionsNabilone pharmacotherapy was safe and well‐tolerated in participants with cannabis dependence. Future studies might evaluate a higher dose of nabilone to determine its effects on cannabis use outcomes in participants with cannabis dependence.Scientific SignificanceThere remains a clear need for additional pharmacotherapy trials for cannabis dependence, and nabilone remains a candidate for such trials. (Am J Addict 2017;XX:1–7)
      PubDate: 2017-09-18T05:00:30.657405-05:
      DOI: 10.1111/ajad.12622
  • Marijuana commercialization and adolescent substance treatment outcomes in
    • Authors: Sean R. LeNoue; Stacy Salomonsen-Sautel, Sung-Joon Min, Christian Thurstone
      First page: 802
      Abstract: Background and ObjectivesIn Colorado, marijuana was legalized for medical use in 2000, commercialized in 2009, and approved for recreational purposes in 2012. Little is known about the association between recent policy changes and adolescent substance treatment outcomes measured by urine drug screens (UDS). This study addressed this research gap.MethodsParticipants were youth (N = 523) aged 11–19 years who were enrolled in an outpatient motivational interviewing (MI)/cognitive behavioral therapy (CBT) plus contingency management (CM) in Denver, Colorado from October 2007 to June 2014. The measures included UDS collected during weekly treatment sessions and sent to a commercial laboratory for quantitative analysis of tetrahydrocannabinol (THC)/Creatinine (Cr). Linear regression models and logistic regression models using a Generalized Estimating Equations (GEE) approach for repeated measures were completed to answer the study aims.ResultsMales, but not females, had a marginally significant increasing trend over time in monthly average THC/Cr (β = 1.99, p = 0.046). There was a significant increasing trend over time (per 30 days) in the odds of having a negative UDS within 6 sessions (OR = 1.02, 95%CI = 1.003–1.04, p = 0.006).Conclusions and Scientific SignificanceBased on these data, substance treatment outcomes from MI and CBT are mixed, but overall treatment appears to remain effective in a state with legalized marijuana. (Am J Addict 2017;XX:1–5)
      PubDate: 2017-10-24T05:35:53.68899-05:0
      DOI: 10.1111/ajad.12634
  • Moderators of response to sertraline versus placebo among recently
           abstinent, cocaine dependent patients: A retrospective analysis of two
           clinical trials
    • Authors: Maryam Bashiri; Michael J. Mancino, Virginia A. Stanick, Jeff Thostenson, Thomas R. Kosten, Alison H. Oliveto
      First page: 807
      Abstract: Background and ObjectivesModerators of treatment response to serotonin reuptake inhibitor sertraline (SRT) for cocaine dependence were assessed in two randomized, double blind, placebo‐controlled clinical trials.MethodsGeneralized estimating equation modeling was performed on data from cocaine‐dependent volunteers randomized to receive SRT or placebo (N = 126) who completed >2‐week drug‐free residential portions of the 12‐week trials, in which subsequent outpatient treatment (weeks 3–12) included weekly cognitive behavioral therapy and thrice‐weekly supervised urine toxicology. Primary Outcome Measure: Relapse (2 consecutive cocaine‐positive or missing urines) following residential stay. Potential moderators included treatment, sex, age, race, depression measures, baseline cocaine urine result, and alcohol dependence diagnosis (ADDx).ResultsOdds ratios (OR) for relapse showed placebo‐treated participants were significantly more likely to relapse than SRT participants. Regardless of treatment condition, participants more likely to relapse were male, and those with lower Hamilton depression ratings, or baseline cocaine‐negative urines. Older subjects or those with current ADDx had higher relapse risk than those without ADDx; however, treating older or ADDx participants with SRT reduced cocaine relapse more than placebo.Discussion and ConclusionsWomen or those with more severe cocaine use or depressive symptoms may have fewer cocaine relapses regardless of medication treatment. SRT at 200 mg reduced cocaine relapse more than placebo, especially in older participants or in those with comorbid ADDx.Scientific SignificanceSRT may be efficacious to support relapse prevention among cocaine‐dependent patients in the context of brief residential followed by outpatient treatment, especially in older participants or those with comorbid alcohol/cocaine dependence. (Am J Addict 2017;XX:1–8)
      PubDate: 2017-11-08T05:31:20.016676-05:
      DOI: 10.1111/ajad.12635
  • Chronic pain and opioid abuse: Factors associated with
           health‐related quality of life
    • Authors: Jermaine D. Jones; Jonathan S. Vogelman, Rachel Luba, Mudassir Mumtaz, Sandra D. Comer
      First page: 815
      Abstract: Background and ObjectivesWhile research on the separate relationships between health‐related quality of life (HRQOL) and chronic pain, and HRQOL and opioid abuse has been sparse, even less work has investigated the factors associated with HRQOL in individuals who have both chronic pain and meet criteria for opioid use disorder. The data presented in this analysis should allow a better understanding the factors important to quality of life among this dual‐diagnosed population.MethodsIndividuals with dual diagnoses of chronic pain and opioid use disorder were recruited for clinical research studies at Columbia University Medical Center. Participants (n = 47) completed inventories to assess pain (Brief Pain Inventory), opioid (ab)use, and depression (Beck Depression Inventory). Variable from these and other inventories, along with demographic factors (age, race, sex, pain severity, depressive symptoms, duration of opioid use, route of opioid use, amount of opioid use) were entered into a regression analysis in order to identify the strongest predictors of SF‐36 Health Survey score.ResultsIn the bivariate analysis we found that demographic and drug use variables were rarely associated with HRQOL. Typically, ratings of pain severity and pain interference were the best predictors. In the multivariate analysis, we found that across the several HRQOL dimensions greater Brief Pain Inventory (BPI) ratings of pain “interference” and Beck Depression Inventory (BDI) scores were consistently associated with lower HRQOL.Conclusions and Scientific SignificanceThese data suggest that insufficient pain management and depression are significant variables contributing to lower quality of life among individuals with chronic pain and opioid use disorder. (Am J Addict 2017;XX:1–7)
      PubDate: 2017-11-21T07:15:19.596813-05:
      DOI: 10.1111/ajad.12637
  • Assessment of risk behaviors in patients with opioid prescriptions: A
           study of indiana's inspect data
    • Authors: Marion S. Greene; Robert Andrew Chambers, Constantin T. Yiannoutsos, Eric R. Wright, Gregory K. Steele, Terrell W. Zollinger
      First page: 822
      Abstract: Background and ObjectivesPrescription Drug Monitoring Programs (PDMPs) can serve as screening tools and support the clinical decision‐making process in patients receiving opioids. The objective of the study was to utilize 2014 INSPECT (Indiana's PDMP) data to identify factors that increase patients’ likelihood to engage in opioid‐related risk behaviors.MethodsBased on a literature review, four risk behaviors were identified: Receiving >90 morphine milligram equivalents (MME), having >4 opioid prescribers, obtaining opioids from >4 pharmacies, and concurrent use of opioids and benzodiazepines. Two binary logistic regression analyses (engaging in at least one risk behaviors; engaging in all four risk behaviors) and an ordinal regression analysis (engaging in 0–4 risk behaviors) were conducted to identify factors associated with these opioid‐related risk behaviors.ResultsOf the 1,538,120 unique opioid patients included in the study, 18.4% engaged in one, 5.3% in two, 1.6% in three, and .4% in all four risk behaviors. Depending on the model, prescribing a second monthly opioid increased patients’ odds to engage in risk behaviors by a factor of 10 or more and prescribing two or more benzodiazepines annually increased the odds at least 13‐fold.Conclusions and Scientific SignificanceAbout one‐fourth of all patients consuming opioids engaged in one or more risk behaviors; higher number of opioid prescriptions and addition of even a small number of benzodiazepine prescriptions dramatically increased these odds. PDMPs can be helpful in identifying opioid users at high‐risk for misuse. This information could be used to target efforts to reduce the prescription drug epidemic. (Am J Addict 2017;XX:1–8)
      PubDate: 2017-11-16T03:31:19.312057-05:
      DOI: 10.1111/ajad.12639
  • Marijuana use and associated motives in Colorado university students
    • Authors: Kristina T. Phillips; Trent L. Lalonde, Michael M. Phillips, Maryia M. Schneider
      First page: 830
      Abstract: Background and ObjectivesMarijuana is the most commonly used illicit drug among college students, with heavy use leading to negative outcomes. Use of marijuana for medical and recreational purposes in select U.S. states has been controversial, with concerns surrounding increased prevalence rates and harm. The current exploratory study aimed to assess marijuana use in college students in Colorado, demographic differences in frequency of use, and motives for using.MethodsCollege students (N = 300; 61% female) were recruited through introductory psychology courses and completed a series of questionnaires and a marijuana urine screen.ResultsAlmost three‐fourths of the sample reported lifetime use of marijuana. Sixty‐five percent used marijuana within the last year and 29% tested positive on the urine screen. Hurdle Poisson regression models with a subset of participants (n = 117) showed non‐Greek and freshman status were associated with increased number of days participants used marijuana in the last month. Problem marijuana use was positively associated with a range of motives—of note—motives focused on coping, boredom, alcohol, and food.Conclusions and Scientific SignificancePrevalence rates of marijuana use were high in this sample of college students in a state with legal recreational marijuana use. Particular students (eg, students who use marijuana to cope) may be at higher risk for problem marijuana use. Developing effective, tailored interventions for university students is warranted. (Am J Addict 2017;XX:1–8)
      PubDate: 2017-11-10T07:20:22.658219-05:
      DOI: 10.1111/ajad.12640
  • Buprenorphine‐naloxone treatment responses differ between young adults
           with heroin and prescription opioid use disorders
    • Authors: Mauricio Romero-Gonzalez; Abtin Shahanaghi, Gregory J. DiGirolamo, Gerardo Gonzalez
      First page: 838
      Abstract: Background and ObjectivesOpioid use disorder among young adults is rising sharply with an increase in morbidity and mortality. This study examined differences in treatment response to a fixed dose of buprenorphine‐naloxone between heroin (HU) and prescriptions opioids (POU) users.MethodsEighty opioid dependent young adults (M = 22 years) were treated with buprenorphine‐naloxone 16–4 mg/day for 8 weeks. Differences between HU (N = 17) and POU (N = 63) on changes in weekly opioid use, opioid craving, withdrawal, and depression symptoms were analyzed with mixed‐effects regression models.ResultsThe HU had an overall mean proportion of weekly opioid use of .32 (SD = .14) compared to POU's weekly mean of .24 (SD = .15) showing a significant main effect (Z = 2.21, p = .02). Depressive symptoms (CES‐D scores) were elevated at baseline for both groups (HU: M = 23.1, SD = 11.9; PO: M = 22.2, SD = 9.4), but only POU improved significantly to a score of 9.88 (SD = 7.4) compared to HU's score of 18.58 (SD = 10.3) at week 8 (Z = 2.24, p = .02). There were no significant differences in treatment retention, craving, or withdrawal symptoms.Discussion and ConclusionsTreatment response to 16‐4 mg/day of buprenorphine–naloxone was significantly diminished for heroin users relative to opioid prescription users in weekly opioid use. Heroin users also had persistent depressive symptoms suggesting the need for close monitoring.Scientific SignificanceThese data suggest that young heroin users might require higher doses of buprenorphine. (Am J Addict 2017;XX:1–7)
      PubDate: 2017-11-16T03:55:25.377183-05:
      DOI: 10.1111/ajad.12641
  • A retrospective cohort study of the health of children prenatally exposed
           to methadone, buprenorphine or naltrexone compared with non‐exposed
           control children
    • Authors: Erin Kelty; Gary Hulse
      First page: 845
      Abstract: Background and ObjectivesLittle is known about the health of children exposed to opioid pharmacotherapies in utero. This study aims to examine the health of children from birth to 5 years of age, who were exposed to methadone, buprenorphine, or naltrexone with non‐exposed children.MethodsChildren were identified by linking the treatment records of women treated with one of the three opioid pharmacotherapies with midwife notifications. Live‐born children exposed to methadone (n = 198), buprenorphine (n = 122), naltrexone (n = 67) in utero, and neonates not prenatally exposed to opioids (n = 387) born between 2001 and 2011 in Western Australia were included in the study. The children were then linked to state mortality, hospital, emergency department (ED), mental health, cancer, and reportable diseases from birth up to their 5th birthday.ResultsOverall rates of hospital admission were elevated in all three treatments as compared with the control children, while rates of ED attendances were only significantly elevated in the methadone (p = .002) and naltrexone (p = .044) exposed children. In terms of both hospital and ED attendances, the differences between the exposed and control children was most apparent in the neonatal period. Rates of mental health out‐patient attendances were elevated in buprenorphine‐exposed children as compared with the control (p = .005).Discussion and ConclusionsThe study provides evidence to suggest a disparity in the health of children exposed to opioid pharmacotherapies in utero compared with non‐exposed control children.Scientific SignificanceExposure to opioid pharmacotherapies in utero may influence the health of children beyond the neonatal period. (Am J Addict 2017;XX:1–7)
      PubDate: 2017-11-16T03:56:17.462591-05:
      DOI: 10.1111/ajad.12642
  • The relationship between hazardous alcohol use and violence among
           street‐involved youth
    • Authors: Nadia Fairbairn; Evan Wood, Sabina Dobrer, Huiru Dong, Thomas Kerr, Kora Debeck
      First page: 852
      Abstract: Background and ObjectivesAlcohol is a major contributor to premature disability and death among youth, often due to physical trauma, violence, and suicide. The purpose of this study was to longitudinally examine the association between hazardous alcohol use and experiences of violence among a cohort of street‐involved youth.MethodsData were derived from the At‐Risk Youth Study (ARYS), a prospective cohort of street‐involved youth who use illicit substances in Vancouver, Canada. The outcome of interest was hazardous alcohol use defined by the US National Institute on Alcohol Abuse and Alcoholism as >14 drinks/week or >5 drinks on one occasion for men, and >7 drinks/week or >4 drinks on one occasion for women. We used Generalized Estimating Equations (GEE) analyses to examine factors independently associated with hazardous alcohol use.ResultsBetween 2005 and 2014, 1,149 drug‐using youth were recruited and 423 (36.8%) reported hazardous alcohol use in the previous 6 months at study baseline. In multivariable GEE analyses, intimate partner violence (Adjusted Odds Ratio [AOR] = 1.53, 95% Confidence Interval [95%CI] = 1.12–2.10), and non‐partner physical assault (AOR = 1.39, 95%CI = 1.21–1.59) were independently associated with hazardous alcohol use after adjusting for multiple potential confounders.Discussion and ConclusionsA considerable proportion of youth in this setting reported hazardous alcohol use, which was independently associated with experiencing recent intimate and non‐partner violence.Scientific SignificanceCombined interventions for violence and hazardous alcohol use should be integrated into service provision programs for street‐involved youth. (Am J Addict 2017;XX:1–7)
      PubDate: 2017-11-21T07:10:21.18658-05:0
      DOI: 10.1111/ajad.12643
  • The impact of mental health comorbidities on adherence to buprenorphine: A
           claims based analysis
    • Authors: Megan Litz; Douglas Leslie
      First page: 859
      Abstract: Background and ObjectivesPrevious research has been inconclusive about whether opioid‐dependent patients with psychiatric comorbidities have shorter treatment retention and higher relapse rates. This study aims to evaluate the impact of mental health comorbidities on adherence to buprenorphine using a large, national health insurance claims data base.MethodsWe used MarketScan® data from 2012 to 2014 to perform this analysis. Inclusion criteria included all patients with an opioid use disorder‐related ICD‐9 code who had been prescribed buprenorphine (n = 2947). Medication adherence was defined using the Medication Possession Ratio ≥.8 (MPR) and logistic regression was used to examine the association between medication adherence and mental health diagnoses, which included Alzheimer's/dementia, schizophrenia, other psychosis, major depressive disorder/bipolar disorder (MDDBP), anxiety disorder, personality disorder, and mental health disorder not elsewhere specified (NOS).ResultsOf the 2947 patients included in our analysis, the most common diagnoses were anxiety disorder: n = 648 (22.0%), MDDBP: n = 467 (15.9%), and mental health disorder NOS: n = 959 (32.5%). Patients diagnosed with MDDBP were significantly less likely to adhere to opioid pharmacotherapy (OR = .805, 95%CI = .651, .994) than patients without MDDBP.Conclusions and Scientific SignificanceThe presence of a psychiatric comorbidity can significantly affect adherence to buprenorphine. These trends illustrate the need for clinicians treating opioid use disorder with buprenorphine to screen for psychiatric disorders and monitor their medication adherence. There may also be opportunities to design interventions to help this vulnerable population adhere to buprenorphine and other forms of opioid pharmacotherapy. (Am J Addict 2017;XX:1–5)
      PubDate: 2017-11-16T04:00:24.498369-05:
      DOI: 10.1111/ajad.12644
  • Mentoring Program
    • First page: 864
      PubDate: 2017-11-22T07:06:20.176543-05:
      DOI: 10.1111/ajad.12651
  • Did You Know'
    • First page: 865
      PubDate: 2017-11-22T07:06:19.9467-05:00
      DOI: 10.1111/ajad.12652
  • PCSS‐MAT Now Offers Free MAT Waiver Training to NPs and PAs!
    • First page: 866
      PubDate: 2017-11-22T07:06:20.462092-05:
      DOI: 10.1111/ajad.12653
  • Two Projects. One Mission.
    • First page: 867
      PubDate: 2017-11-22T07:06:20.42511-05:0
      DOI: 10.1111/ajad.12654
  • Attending the 28th Annual Meeting and Scientific Symposium'
    • First page: 868
      PubDate: 2017-11-22T07:06:18.291483-05:
      DOI: 10.1111/ajad.12655
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