Subjects -> MEDICAL SCIENCES (Total: 8529 journals)
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    - INTERNAL MEDICINE (167 journals)
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    - MEDICAL GENETICS (58 journals)
    - MEDICAL SCIENCES (2342 journals)
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    - SURGERY (401 journals)
    - UROLOGY, NEPHROLOGY AND ANDROLOGY (153 journals)

MEDICAL SCIENCES (2342 journals)                  1 2 3 4 5 6 7 8 | Last

Showing 1 - 200 of 3562 Journals sorted alphabetically
16 de Abril     Open Access   (Followers: 3)
3D Printing in Medicine     Open Access   (Followers: 4)
4 open     Open Access  
AADE in Practice     Hybrid Journal   (Followers: 6)
ABCS Health Sciences     Open Access   (Followers: 9)
Abia State University Medical Students' Association Journal     Full-text available via subscription   (Followers: 2)
AboutOpen     Open Access  
ACIMED     Open Access   (Followers: 1)
ACS Medicinal Chemistry Letters     Hybrid Journal   (Followers: 48)
Acta Bio Medica     Full-text available via subscription   (Followers: 2)
Acta Bioethica     Open Access  
Acta Bioquimica Clinica Latinoamericana     Open Access   (Followers: 1)
Acta Científica Estudiantil     Open Access  
Acta Facultatis Medicae Naissensis     Open Access   (Followers: 1)
Acta Herediana     Open Access  
Acta Informatica Medica     Open Access  
Acta Medica (Hradec Králové)     Open Access  
Acta Medica Bulgarica     Open Access  
Acta Medica Colombiana     Open Access   (Followers: 1)
Acta Médica Costarricense     Open Access   (Followers: 2)
Acta Medica Indonesiana     Open Access  
Acta Medica International     Open Access  
Acta medica Lituanica     Open Access  
Acta Medica Marisiensis     Open Access  
Acta Medica Martiniana     Open Access  
Acta Medica Nagasakiensia     Open Access   (Followers: 1)
Acta Medica Peruana     Open Access   (Followers: 2)
Acta Médica Portuguesa     Open Access  
Acta Medica Saliniana     Open Access  
Acta Scientiarum. Health Sciences     Open Access   (Followers: 2)
Acupuncture & Electro-Therapeutics Research     Full-text available via subscription   (Followers: 6)
Acupuncture and Natural Medicine     Open Access  
Addiction Science & Clinical Practice     Open Access   (Followers: 8)
Addictive Behaviors Reports     Open Access   (Followers: 9)
Adıyaman Üniversitesi Sağlık Bilimleri Dergisi / Health Sciences Journal of Adıyaman University     Open Access   (Followers: 1)
Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi     Open Access   (Followers: 1)
Advanced Biomedical Research     Open Access  
Advanced Health Care Technologies     Open Access   (Followers: 10)
Advanced Science, Engineering and Medicine     Partially Free   (Followers: 9)
Advanced Therapeutics     Hybrid Journal   (Followers: 1)
Advances in Bioscience and Clinical Medicine     Open Access   (Followers: 8)
Advances in Cell and Gene Therapy     Hybrid Journal   (Followers: 2)
Advances in Clinical Chemistry     Full-text available via subscription   (Followers: 27)
Advances in Clinical Radiology     Full-text available via subscription   (Followers: 2)
Advances in Life Course Research     Hybrid Journal   (Followers: 10)
Advances in Lipobiology     Full-text available via subscription   (Followers: 1)
Advances in Medical Education and Practice     Open Access   (Followers: 32)
Advances in Medical Ethics     Open Access   (Followers: 1)
Advances in Medical Research     Open Access   (Followers: 2)
Advances in Medical Sciences     Hybrid Journal   (Followers: 9)
Advances in Medicinal Chemistry     Full-text available via subscription   (Followers: 6)
Advances in Medicine     Open Access   (Followers: 3)
Advances in Microbial Physiology     Full-text available via subscription   (Followers: 5)
Advances in Molecular Oncology     Open Access   (Followers: 2)
Advances in Molecular Toxicology     Full-text available via subscription   (Followers: 7)
Advances in Parkinson's Disease     Open Access   (Followers: 1)
Advances in Phytomedicine     Full-text available via subscription  
Advances in Preventive Medicine     Open Access   (Followers: 6)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 20)
Advances in Regenerative Medicine     Open Access   (Followers: 3)
Advances in Skeletal Muscle Function Assessment     Open Access  
Advances in Therapy     Hybrid Journal   (Followers: 5)
Advances in Traditional Medicine     Hybrid Journal   (Followers: 2)
Advances in Veterinary Science and Comparative Medicine     Full-text available via subscription   (Followers: 15)
Advances in Virus Research     Full-text available via subscription   (Followers: 6)
Advances in Wound Care     Hybrid Journal   (Followers: 14)
Aerospace Medicine and Human Performance     Full-text available via subscription   (Followers: 13)
African Health Sciences     Open Access   (Followers: 4)
African Journal of Biomedical Research     Open Access   (Followers: 1)
African Journal of Clinical and Experimental Microbiology     Open Access   (Followers: 4)
African Journal of Laboratory Medicine     Open Access   (Followers: 2)
African Journal of Medical and Health Sciences     Open Access   (Followers: 3)
African Journal of Thoracic and Critical Care Medicine     Open Access  
African Journal of Trauma     Open Access   (Followers: 1)
Afrimedic Journal     Open Access   (Followers: 2)
Aggiornamenti CIO     Hybrid Journal   (Followers: 1)
AIDS Research and Human Retroviruses     Hybrid Journal   (Followers: 9)
AJOB Empirical Bioethics     Hybrid Journal   (Followers: 3)
AJSP: Reviews & Reports     Hybrid Journal  
Aktuelle Ernährungsmedizin     Hybrid Journal   (Followers: 4)
Al-Azhar Assiut Medical Journal     Open Access   (Followers: 2)
Al-Qadisiah Medical Journal     Open Access   (Followers: 1)
Alerta : Revista Científica del Instituto Nacional de Salud     Open Access  
Alexandria Journal of Medicine     Open Access   (Followers: 1)
Allgemeine Homöopathische Zeitung     Hybrid Journal   (Followers: 3)
Alpha Omegan     Full-text available via subscription  
ALTEX : Alternatives to Animal Experimentation     Open Access   (Followers: 2)
Althea Medical Journal     Open Access   (Followers: 2)
American Journal of Biomedical Engineering     Open Access   (Followers: 15)
American Journal of Biomedical Research     Open Access   (Followers: 2)
American Journal of Biomedicine     Full-text available via subscription   (Followers: 7)
American Journal of Chinese Medicine, The     Hybrid Journal   (Followers: 4)
American Journal of Clinical Medicine Research     Open Access   (Followers: 8)
American Journal of Family Therapy     Hybrid Journal   (Followers: 10)
American Journal of Law & Medicine     Full-text available via subscription   (Followers: 12)
American Journal of Lifestyle Medicine     Hybrid Journal   (Followers: 6)
American Journal of Managed Care     Full-text available via subscription   (Followers: 12)
American Journal of Medical Case Reports     Open Access   (Followers: 1)
American Journal of Medical Sciences and Medicine     Open Access   (Followers: 4)
American Journal of Medicine     Hybrid Journal   (Followers: 51)
American Journal of Medicine and Medical Sciences     Open Access   (Followers: 1)
American Journal of Medicine Studies     Open Access   (Followers: 3)
American Journal of Medicine Supplements     Full-text available via subscription   (Followers: 3)
American Journal of the Medical Sciences     Hybrid Journal   (Followers: 12)
American Journal on Addictions     Hybrid Journal   (Followers: 10)
American medical news     Free   (Followers: 3)
American Medical Writers Association Journal     Full-text available via subscription   (Followers: 6)
Amyloid: The Journal of Protein Folding Disorders     Hybrid Journal   (Followers: 5)
Anales de la Facultad de Medicina     Open Access  
Anales de la Facultad de Medicina, Universidad de la República, Uruguay     Open Access  
Anales del Sistema Sanitario de Navarra     Open Access   (Followers: 1)
Analgesia & Resuscitation : Current Research     Hybrid Journal   (Followers: 6)
Anatolian Clinic the Journal of Medical Sciences     Open Access  
Anatomica Medical Journal     Open Access  
Anatomical Science International     Hybrid Journal   (Followers: 3)
Anatomical Sciences Education     Hybrid Journal   (Followers: 2)
Anatomy     Open Access   (Followers: 3)
Anatomy Research International     Open Access   (Followers: 4)
Angewandte Schmerztherapie und Palliativmedizin     Hybrid Journal  
Angiogenesis     Hybrid Journal   (Followers: 3)
Ankara Medical Journal     Open Access   (Followers: 2)
Ankara Üniversitesi Tıp Fakültesi Mecmuası     Open Access  
Annales de Pathologie     Full-text available via subscription  
Annales des Sciences de la Santé     Open Access  
Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale     Full-text available via subscription   (Followers: 3)
Annals of African Medicine     Open Access   (Followers: 2)
Annals of Anatomy - Anatomischer Anzeiger     Hybrid Journal   (Followers: 3)
Annals of Bioanthropology     Open Access   (Followers: 5)
Annals of Biomedical Engineering     Hybrid Journal   (Followers: 19)
Annals of Biomedical Sciences     Full-text available via subscription   (Followers: 4)
Annals of Clinical Hypertension     Open Access  
Annals of Clinical Microbiology and Antimicrobials     Open Access   (Followers: 14)
Annals of Family Medicine     Open Access   (Followers: 15)
Annals of Health Research     Open Access   (Followers: 1)
Annals of Ibadan Postgraduate Medicine     Open Access  
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Medicine     Hybrid Journal   (Followers: 12)
Annals of Medicine and Surgery     Open Access   (Followers: 7)
Annals of Microbiology     Hybrid Journal   (Followers: 13)
Annals of Musculoskeletal Medicine     Open Access   (Followers: 1)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Rehabilitation Medicine     Open Access  
Annals of Saudi Medicine     Open Access  
Annals of the College of Medicine, Mosul     Open Access   (Followers: 1)
Annals of the New York Academy of Sciences     Hybrid Journal   (Followers: 5)
Annals of The Royal College of Surgeons of England     Full-text available via subscription   (Followers: 3)
Annual Reports in Medicinal Chemistry     Full-text available via subscription   (Followers: 7)
Annual Reports on NMR Spectroscopy     Full-text available via subscription   (Followers: 5)
Annual Review of Medicine     Full-text available via subscription   (Followers: 18)
Anthropological Review     Open Access   (Followers: 24)
Anthropologie et santé     Open Access   (Followers: 5)
Antibiotics     Open Access   (Followers: 9)
Antibodies     Open Access   (Followers: 2)
Antibody Reports     Open Access  
Antibody Technology Journal     Open Access   (Followers: 1)
Antibody Therapeutics     Open Access  
Anuradhapura Medical Journal     Open Access  
Anwer Khan Modern Medical College Journal     Open Access   (Followers: 2)
Apmis     Hybrid Journal   (Followers: 2)
Apparence(s)     Open Access   (Followers: 1)
Applied Clinical Informatics     Hybrid Journal   (Followers: 4)
Applied Clinical Research, Clinical Trials and Regulatory Affairs     Hybrid Journal   (Followers: 2)
Applied Medical Informatics     Open Access   (Followers: 14)
Arab Journal of Nephrology and Transplantation     Open Access   (Followers: 1)
Archive of Biomedical Science and Engineering     Open Access   (Followers: 1)
Archive of Clinical Medicine     Open Access   (Followers: 1)
Archive of Community Health     Open Access   (Followers: 1)
Archives Medical Review Journal / Arşiv Kaynak Tarama Dergisi     Open Access  
Archives of Asthma, Allergy and Immunology     Open Access  
Archives of Clinical Hypertension     Open Access   (Followers: 1)
Archives of Medical and Biomedical Research     Open Access   (Followers: 3)
Archives of Medical Laboratory Sciences     Open Access   (Followers: 1)
Archives of Medicine and Health Sciences     Open Access   (Followers: 4)
Archives of Medicine and Surgery     Open Access  
Archives of Organ Transplantation     Open Access   (Followers: 1)
Archives of Preventive Medicine     Open Access   (Followers: 1)
Archives of Pulmonology and Respiratory Care     Open Access   (Followers: 1)
Archives of Renal Diseases and Management     Open Access   (Followers: 1)
Archives of Trauma Research     Open Access   (Followers: 4)
Archivos de Medicina (Manizales)     Open Access  
ArgoSpine News & Journal     Hybrid Journal  
Arquivos Brasileiros de Oftalmologia     Open Access   (Followers: 1)
Arquivos de Ciências da Saúde     Open Access  
Arquivos de Medicina     Open Access  
Ars Medica : Revista de Ciencias Médicas     Open Access  
ARS Medica Tomitana     Open Access   (Followers: 1)
Art Therapy: Journal of the American Art Therapy Association     Hybrid Journal   (Followers: 18)
Arterial Hypertension     Open Access   (Followers: 1)
Artificial Intelligence in Medicine     Hybrid Journal   (Followers: 18)
Artificial Organs     Hybrid Journal   (Followers: 1)
ASHA Leader     Open Access   (Followers: 3)
Asia Pacific Family Medicine Journal     Open Access   (Followers: 2)
Asia Pacific Journal of Clinical Nutrition     Full-text available via subscription   (Followers: 13)
Asia Pacific Journal of Clinical Trials : Nervous System Diseases     Open Access  
Asian Bioethics Review     Full-text available via subscription   (Followers: 3)
Asian Biomedicine     Open Access   (Followers: 2)
Asian Journal of Cell Biology     Open Access   (Followers: 6)
Asian Journal of Health     Open Access   (Followers: 3)
Asian Journal of Medical and Biological Research     Open Access   (Followers: 5)
Asian Journal of Medical and Pharmaceutical Researches     Open Access   (Followers: 2)

        1 2 3 4 5 6 7 8 | Last

Similar Journals
Journal Cover
American Journal of the Medical Sciences
Journal Prestige (SJR): 0.767
Citation Impact (citeScore): 1
Number of Followers: 12  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 0002-9629
Published by Elsevier Homepage  [3203 journals]
  • Severe Rhabdomyolysis in Glucose-6-Phosphate Dehydrogenase Deficiency
    • Abstract: Publication date: Available online 2 April 2020Source: The American Journal of the Medical SciencesAuthor(s): Balraj Singh, Parminder Kaur, Kok Hoe Chan, Robert G. Lahita, Michael Maroules, Chandra Chandran
       
  • Relationship between particulate matter (PM2.5) and hospitalizations and
           mortality of chronic obstruective pulmlonary disease patients: A
           meta-analysis
    • Abstract: Publication date: Available online 2 April 2020Source: The American Journal of the Medical SciencesAuthor(s): Rui-Xia Zhu, Xiu-Hong Nie, Ya-Hong Chen, Jin Chen, Shao-Wei Wu, Li-Hua Zhao
       
  • Chilaiditi Syndrome secondary to hepatic migration in a patient with
           bilateral diaphragmatic palsy
    • Abstract: Publication date: Available online 19 March 2020Source: The American Journal of the Medical SciencesAuthor(s): Biplab K. Saha, Alyssa Bonnier
       
  • An Educational Initiative to Reduce Inpatient Fecal Occult Blood Testing
    • Abstract: Publication date: Available online 19 March 2020Source: The American Journal of the Medical SciencesAuthor(s): Jared Rejeski, Patrick Green
       
  • Seabather's eruption
    • Abstract: Publication date: Available online 19 March 2020Source: The American Journal of the Medical SciencesAuthor(s): Abheek Sil, Avik Panigrahi, Sayantani Chakraborty
       
  • Ulcerated lesions of the midline gingiva and soft palate
    • Abstract: Publication date: Available online 19 March 2020Source: The American Journal of the Medical SciencesAuthor(s): Toshihiro Nagato, Miki Takahara, Yasuaki Harabuchi
       
  • Thoracic Splenule (Post-traumatic Autotransplantation of Splenic Tissue)
    • Abstract: Publication date: April 2020Source: The American Journal of the Medical Sciences, Volume 359, Issue 4Author(s): Abdulmonam Ali, Naga Srinivas Sirikonda
       
  • Biventricular Pulsus Alternans: “Stolen Pulses” Seen by
           Echocardiography in Pulmonary Hypertension
    • Abstract: Publication date: April 2020Source: The American Journal of the Medical Sciences, Volume 359, Issue 4Author(s): Yu Kang, Liuyu Yu, Qing Zhang
       
  • Acute Onset Hyperammonemic Encephalopathy Related to Fibrolamellar
           Carcinoma: Another One Bites the Dust
    • Abstract: Publication date: April 2020Source: The American Journal of the Medical Sciences, Volume 359, Issue 4Author(s): Rodrigo C.T. Surjan, Sergio P. Silveira, João Lucas S. Pinheiro, Pedro Henrique S. Pinheiro, Mauricio F.A. Barros, Silvia Regina P. Soares
       
  • An Unexpected Case of Lagochilascariasis: Interdisciplinary Management and
           Use of 12S and 18S rDNA Analysis
    • Abstract: Publication date: April 2020Source: The American Journal of the Medical Sciences, Volume 359, Issue 4Author(s): Fernando Martinez-Hernandez, Hector Manuel Prado-Calleros, Juan Pablo Ramirez-Hinojosa, Vladimir Figueroa-Angel, Maria Teresa Lopez-Reynoso, Maria del Carmen Jimenez-Andrade, Isaias Estrada-Moscoso, Nancy Rivas, Javier Escobedo-Ortegon, Ana Flisser, Mirza Gabriela Romero-Valdovinos, Pablo Maravilla
       
  • A Hooked Worm!
    • Abstract: Publication date: April 2020Source: The American Journal of the Medical Sciences, Volume 359, Issue 4Author(s): Satvinder Singh Bakshi, B. Sajeeth Manikanda Prabu
       
  • Lower Gastrointestinal Bleeding in Patients With Cirrhosis—Etiology
           and Outcomes
    • Abstract: Publication date: April 2020Source: The American Journal of the Medical Sciences, Volume 359, Issue 4Author(s): Ali Khalifa, Don C. Rockey
       
  • Bilateral Scrotal Masses as a Clue to Diagnosis of Genetic Disease
    • Abstract: Publication date: April 2020Source: The American Journal of the Medical Sciences, Volume 359, Issue 4Author(s): Sakditad Saowapa, Touch Ativitavas, Chutintorn Sriphrapradang
       
  • Numerous black elevations in the stomach and duodenum
    • Abstract: Publication date: Available online 18 March 2020Source: The American Journal of the Medical SciencesAuthor(s): Myung-Won Lee, Hyo Jin Lee
       
  • WASF3 knockdown sensitizes gastric cancer cells to oxaliplatin by
           inhibiting ATG12-mediated autophagy
    • Abstract: Publication date: Available online 13 March 2020Source: The American Journal of the Medical SciencesAuthor(s): Yanli Nie, Xinjun Liang, Sanhe Liu, Fang Guo, Na Fang, Fuxiang Zhou
       
  • Diagnostic Challenges and Dilemmas in Tuberculous Meningitis
    • Abstract: Publication date: Available online 13 March 2020Source: The American Journal of the Medical SciencesAuthor(s): Supavit Chesdachai, Benjamin Katz, Smarika Sapkota
       
  • Quantifying the Economic Burden of Acute Myocardial Infarction: A Timely
           and Important Concept
    • Abstract: Publication date: Available online 12 March 2020Source: The American Journal of the Medical SciencesAuthor(s): Adam E. Berman, D. Douglas Miller
       
  • Familial Adenomatous Polyposis
    • Abstract: Publication date: Available online 12 March 2020Source: The American Journal of the Medical SciencesAuthor(s): Abhishek Bhurwal, Gina Prochilo, Anish Vinit Patel
       
  • Cardiac Silhouette
    • Abstract: Publication date: Available online 11 March 2020Source: The American Journal of the Medical SciencesAuthor(s): Bo-Sheng Wu, Chih-Yu Yang, Oscar Kuang-Sheng Lee
       
  • Clinical characteristics, comorbidities and prognosis in patients with
           Heart Failure with Mid-Range Ejection Fraction
    • Abstract: Publication date: Available online 11 March 2020Source: The American Journal of the Medical SciencesAuthor(s): Ghulam Murtaza, Timir K Paul, Zia Ur Rahman, Danielle Kelvas, Steven J. Lavine
       
  • Emphysematous Pancreatitis in the Elderly
    • Abstract: Publication date: Available online 11 March 2020Source: The American Journal of the Medical SciencesAuthor(s): Yu-Jang Su, Yen-Chun Lai, Chin-Yao Chou, Hsiu-Wu Yang, Chen-Wang Chang
       
  • MicroRNA-294 promotes cell proliferation, migration, and invasion in
           SMMC-7721 hepatoma carcinoma cells by activating the JNK/ERK signaling
           pathway
    • Abstract: Publication date: Available online 9 March 2020Source: The American Journal of the Medical SciencesAuthor(s): Xianping Cheng, Mo Chen, Zhenyun Liu
       
  • Five-Year Glycemic Trajectories among Healthy African-American and
           European-American Offspring of Parents with Type 2 Diabetes
    • Abstract: Publication date: Available online 9 March 2020Source: The American Journal of the Medical SciencesAuthor(s): Laleh N Razavi, Sotonte Ebenibo, Chimaroke Edeoga, Jim Wan, Samuel Dagogo-Jack
       
  • The Effect of Sex-Diabetes Mellitus Interactions and Insulin on Cardiac
           Outcomes After a Myocardial Infarction
    • Abstract: Publication date: Available online 8 March 2020Source: The American Journal of the Medical SciencesAuthor(s): Gayatri Pemmasani, Srikanth Yandrapalli
       
  • Alu methylation and risk of cancer: a meta-analysis
    • Abstract: Publication date: Available online 8 March 2020Source: The American Journal of the Medical SciencesAuthor(s): Ding Ye, Danjie Jiang, Xinhan Zhang, Yingying Mao
       
  • Spontaneous Coronary Thrombosis in A Young Patient with Nephrotic Syndrome
    • Abstract: Publication date: Available online 4 March 2020Source: The American Journal of the Medical SciencesAuthor(s): Fei Chen, Yong Peng, Mao Chen
       
  • Estimating the Economic Burden of Acute Myocardial Infarction in the US:
           12 Year National Data
    • Abstract: Publication date: Available online 21 February 2020Source: The American Journal of the Medical SciencesAuthor(s): Kinfe G. Bishu, Alain Lekoubou, Elizabeth Kirkland, Samuel O. Schumann, Andrew Schreiner, Marc Heincelman, William P. Moran, Patrick D. Mauldin
       
  • Kartagener syndrome
    • Abstract: Publication date: Available online 21 February 2020Source: The American Journal of the Medical SciencesAuthor(s): Bi-cui Liu, Ting-xuan Huang, Chun-Tao Liu
       
  • Pseudotumor of the Lung
    • Abstract: Publication date: March 2020Source: The American Journal of the Medical Sciences, Volume 359, Issue 3Author(s): Myung-Won Lee, Hyo Jin Lee
       
  • Janus Kinase 2 Mutation-Associated Budd-Chiari Syndrome Presenting as a
           Tumor
    • Abstract: Publication date: March 2020Source: The American Journal of the Medical Sciences, Volume 359, Issue 3Author(s): Cheng-Mao Shen, Wei-Chou Chang, Hsuan-Hwai Lin
       
  • Pentazocine-Induced Skin Ulcers
    • Abstract: Publication date: March 2020Source: The American Journal of the Medical Sciences, Volume 359, Issue 3Author(s): Kamal Kant Sahu, Gitesh Upendra Sawatkar, Shamendra Anand Sahu, Ajay Kumar Mishra, Amos Lal
       
  • Disseminated Dermal Gout
    • Abstract: Publication date: March 2020Source: The American Journal of the Medical Sciences, Volume 359, Issue 3Author(s): Jasmeet Gill, Mark Feldman
       
  • Triple Negative Mutations in Essential Thrombocythemia With bcr-abl
           Rearrangement: Is There a Such Distinct Disease'
    • Abstract: Publication date: March 2020Source: The American Journal of the Medical Sciences, Volume 359, Issue 3Author(s): Andrei Braester, Masad Barhoum
       
  • Systemic Tuberculosis Mimicking Lung Cancer With Multiple Metastases
    • Abstract: Publication date: March 2020Source: The American Journal of the Medical Sciences, Volume 359, Issue 3Author(s): Chou-Chin Lan, Chih-Wei Wu, Yao-Kuang Wu
       
  • The Characteristics of Intestinal-Barrier Damage in Rats With IgA
           Nephropathy
    • Abstract: Publication date: March 2020Source: The American Journal of the Medical Sciences, Volume 359, Issue 3Author(s): Nan Zhou, Ying Shen, Lirong Fan, Qiang Sun, Canxing Huang, Jing Hao, Jingchao Lan, Huimin YanAbstractBackgroundIntestinal-barrier damage plays an important pathogenic role in immunoglobulin A nephropathy (IgAN). In this study, we explored the characteristics of the intestinal barrier in rats with IgAN.Materials and MethodsWe randomly divided 17 Sprague Dawley (SD) male rats into a normal control group (NC; n = 9) and an IgAN model group (n = 8). Feces in the distal ileum were taken for intestinal-microbiota 16sDNA sequencing. We also took a segment of terminal ileum to analyze intestinal morphology and to detect mRNA and protein expression of the tight-junction proteins zonula occludens-1 (ZO-1) and occludin (OCLN), as well as of mucin 2 (MUC2). We then measured levels of serum diamine oxidase (DAO) and D-lactic acid (D-LA), the biomarkers of intestinal permeability.ResultsCompared with the NC group, mRNA expression levels of ZO-1 (t = 4.216, P = 0.0007), OCLN (t = 2.413, P = 0.029) and MUC2 (t = 0.859, P < 0.0001) were significantly decreased in the IgAN model group. Protein expression of ZO-1 (t = 7.349, P < 0.0001) and OCLN (t = 6.367, P < 0.0001) was also decreased in the IgAN model group. Conversely, serum DAO (t = 3.758, P = 0.0024) and D-LA (t = 2.246, P = 0.0427) levels increased in this group. At the genus level, the relative abundance of Ruminococcus2 (P = 0.0086) was increased in the IgAN model group.ConclusionsDecreased expression of ZO-1, OCLN and MUC2, plus intestinal-microbiota dysbiosis, are associated with intestinal-barrier damage in IgAN rats.
       
  • Actin-Bundling Proteins (Actinin-4 and Fascin-1) are Involved in the
           Development of Pancreatic Intraepithelial Neoplasia (PanIN)
    • Abstract: Publication date: March 2020Source: The American Journal of the Medical Sciences, Volume 359, Issue 3Author(s): Magdalena Misiura, Justyna Zińczuk, Konrad Zaręba, Dorota Kamińska, Katarzyna Guzińska-Ustymowicz, Anna PryczyniczABSTRACTBackgroundFascin-1 and actinin-4 are involved in key processes of tumor cell adhesion, migration and metastasis. Actinin-4 plays an important role in promotion of cell proliferation, whereas fascin-1 regulates cellular motility. Its over-expression leads to the loss of cell adhesion and metastasis. The aim of our study was to assess fascin-1 and actinin-4 expression in normal pancreatic ducts and in pancreatic intraepithelial neoplasia (PanIN) – precursor lesion of pancreatic ductal adenocarcinoma (PDAC).Materials and MethodsThe study involved 70 patients treated surgically due to PDAC, cysts and pancreatitis, who had also been diagnosed with pancreatic intraepithelial neoplasia. Fascin-1 and actinin-4 expressions were evaluated using the immunohistochemistry method.ResultsA statistically significant relationship was observed between the expression of fascin-1 and actinin-4 (cytoplasmic) and patients’ age (P = 0.01, P = 0.002, respectively). The expression of fascin-1 and actinin-4 was associated with the diagnosis (P 
       
  • Jailed in a Bony Prison: Post-tuberculotic Calcific Constrictive
           Pericarditis
    • Abstract: Publication date: March 2020Source: The American Journal of the Medical Sciences, Volume 359, Issue 3Author(s): Georgia Vogiatzi, Konstantinos Aznaouridis, Panagiotis Tolis, Eleftherios Tsiamis, Dimitris Tousoulis
       
  • Does Clindamycin Induce Acute Kidney Injury'
    • Abstract: Publication date: Available online 20 February 2020Source: The American Journal of the Medical SciencesAuthor(s): Amara Sarwal, Chia-Yu Chiu, Addi Feinstein
       
  • Staghorn Renal Stone with Magnesium Ammonium Phosphates Crystals
    • Abstract: Publication date: Available online 17 February 2020Source: The American Journal of the Medical SciencesAuthor(s): Yi-An Hu, Pei-Chang Lee, Szu-Yuan Li
       
  • Why Did The Original Jones Criteria Not Emphasize Streptococcal
           Infection'
    • Abstract: Publication date: Available online 10 February 2020Source: The American Journal of the Medical SciencesAuthor(s): Stanford T. ShulmanAbstractT. Duckett Jones’ 1944 Jones Criteria for the diagnosis of Acute Rheumatic Fever did not require preceding group A streptococcal infection despite widely accepted strong evidence by Alvin Coburn and others.We reviewed relevant literature, previously unknown 1943 T. D. Jones correspondence, and Coburn's autobiography and archival material. New information concerning the fraught Jones-Coburn personal relationship very likely explains Jones’ unwillingness to accept Coburn's 1931 discovery of the crucial streptococcal link. Shortly after Jones’ 1954 death, the Jones Criteria were revised to emphasize the essential streptococcal role. Despite clear evidence in his correspondence that Jones fully understood the strength of the group A Streptococcal-Rheumatic Fever link before 1944, he failed to acknowledge this in the original Jones Criteria and denied it to his death in 1954. This episode demonstrates how interpersonal relationships have the potential to interfere with acceptance of new medical data.
       
  • Utility of circulating tumor cells for detection of early-stage luminal A
           breast cancer
    • Abstract: Publication date: Available online 7 February 2020Source: The American Journal of the Medical SciencesAuthor(s): Yang Zhang, Ji Qi, Jianyi Li, Shi Jia, Yitong Wang, Qiang Sun, Ye Kang, Yushi Liu, Yanan Cao, Jiaxin YuABSTRACTBackgroundPatients with early-stage luminal A breast cancer (LABC) have better prognoses. However, follow-up examinations are frequent and remain complex. The present study examined whether circulating tumor cell (CTC) detection could be used as an earlier and more reproducible indicator of disease status among patients with early-stage LABC, and given China's healthcare resource challenges, whether it could periodically replace follow-up routine imaging.MethodsA total of 135 postoperative Chinese patients with early-stage LABC were randomly assigned to a CTC group (68 patients underwent alternating assessments using CTC detection and routine re-examination) or control group (67 patients underwent only routine re-examination). The prognosis and patient-covered costs of the various assessments were calculated for the two groups.ResultsNo patients had normal CTCs and simultaneous abnormal imaging findings. There were no differences in overall survival, disease-free survival, and total patient-covered cost of follow-up between the two groups (all P> 0.05). However, there was a significant difference in the average patient-covered cost (P < 0.001). Furthermore, significant inter-group differences were observed in the total and average hospitalization times (P < 0.05).ConclusionsAmong Chinese patients with low-risk LABC, CTC detection was highly reliable and relatively low cost. Therefore, CTC detection may be used to reduce the number of routine imaging follow-ups.
       
  • Prognostic utility of monocyte to high-density lipoprotein ratio in
           patients with acute coronary syndrome: A meta-analysis
    • Abstract: Publication date: Available online 27 January 2020Source: The American Journal of the Medical SciencesAuthor(s): Miying Sun, Dongming Zhao, Yanqi Zhang, Yujia Zhai, Mingzhe Ye, Xinpeng Wang, Lina Zheng, Liying WangAbstractBackgroundThe monocyte to high-density lipoprotein ratio (MHR) has been used to predict adverse clinical outcomes in patients with acute coronary syndrome (ACS). This meta-analysis aimed to evaluate the prognostic utility of MHR in patients with ACS.MethodsWe comprehensively searched for relevant studies in Pubmed, Embase, CNKI, WanFang, and VIP databases until March 12, 2019. Epidemiological studies investigating the association between MHR and major adverse cardiovascular events (MACE) or all-cause mortality in patients with ACS were included. Pooled effect was expressed as risk ratios (RR) with 95% confidence intervals (CI) for the highest versus the reference lower MHR group.ResultsEight studies involving 6,480 patients with ACS were included and analyzed. Meta-analysis indicated that the highest MHR was significantly associated with higher risk of MACE (RR 1.65; 95%CI 1.36–2.02) and all-cause mortality (RR 2.61; 95%CI 1.29–4.89) after adjusting for the conventional confounders. The prognostic values of MACE with the highest MHR caused no significant changes in the in-hospital follow-up (RR 1.76; 95%CI 1.34–2.32) and>6 months follow-up (RR 1.68; 95%CI 1.08–2.62) subgroups. Furthermore, ST elevation myocardial infarction patients with the highest MHR had a 2.07-fold higher risk of in-hospital MACE (RR 2.07; 95%CI 1.52–2.80).ConclusionsElevated MHR is independently associated with an increased risk of MACE and all-cause mortality in patients with ACS. MHR may serve as a potential prognostic indicator for ACS prognosis.
       
  • Causes of Lower Gastrointestinal Bleeding in Cirrhotics: Are the Most
           Commonly Reported Causes the Most Common'
    • Abstract: Publication date: Available online 25 January 2020Source: The American Journal of the Medical SciencesAuthor(s): Mohamed Shoreibah, C Mel Wilcox
       
  • Re: “Gender Disparity in Authorship of Peer Reviewed Medical
           Publications” Bernardi et al.
    • Abstract: Publication date: Available online 25 January 2020Source: The American Journal of the Medical SciencesAuthor(s): Halah Ibrahim, Sophia Archuleta, Dora J. Stadler, Joseph Cofrancesco
       
  • A Rare Presentation of Gout: Achilles Tendinopathy, Ultrasonographic
           Assessment
    • Abstract: Publication date: Available online 23 January 2020Source: The American Journal of the Medical SciencesAuthor(s): Cevriye Mülkoğlu, Barış Nacır, Hakan Genç
       
  • Type 2 Diabetes and Chronic Conditions Disparities in Medicare
           Beneficiaries in the State of Michigan
    • Abstract: Publication date: Available online 23 January 2020Source: The American Journal of the Medical SciencesAuthor(s): John M Clements, Mariana Rosca, Carla Cavallin, Shelby Falkenhagen, Thomas Ittoop, Christina K Jung, Megan Mazzella, Joseph A Reed, Megan Schluentz, Caleb VanDykeABSTRACTBackground: This study aimed to describe the prevalence of type 2 diabetes and combinations of multiple chronic conditions (MCCs) that are leading causes of death (LCD) and confirm that disparities exist between groups based on race and sex.Methods: We conducted a retrospective cohort study using 2012 Medicare claims data from beneficiaries with type 2 diabetes over the age of 65 in the state of Michigan.Results: Female beneficiaries have type 2 diabetes and one or more MCCs that are LCD more often than males. Most type 2 diabetes patients have diabetes alone without MCCs, while a large proportion have at least one additional chronic condition that is a LCD. One in three patients have three or more chronic conditions. The most prevalent type 2 diabetes coexisting MCCs are congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD), and chronic kidney disease (CKD). Asian/Pacific Islanders have the highest prevalence of type 2 diabetes without MCCs, and the highest prevalence of diabetes plus CHF. While fewer black beneficiaries have diabetes alone or one additional MCC, the prevalence of three or more MCCs in blacks generally exceeds the prevalence in other races. In beneficiaries with newly diagnosed type 2 diabetes, COPD and CHF are the first new chronic conditions to be diagnosed after an initial type 2 diabetes diagnosis.Conclusions: Race and sex disparities occur in the prevalence of type 2 diabetes and MCCs that are LCD in Medicare beneficiaries in the state of Michigan.
       
  • Acarbose vs. Repaglinide in Diabetes Treatment: A New Appraisal of Two Old
           Rivals
    • Abstract: Publication date: Available online 23 January 2020Source: The American Journal of the Medical SciencesAuthor(s): Reza Pishdad, Parisa Pishdad, Gholam Reza PishdadAbstractBackgroundAcarbose and repaglinide are two safe and effective anti-diabetic agents that are especially in wide use in Asian and Middle Eastern countries. These two prandial agents share some outstanding qualities that their newer counterparts don't: While globally available in generic versions, both are oral and cheap. There is a paucity of data regarding their comparative efficacy. Herein, a head-to-head comparison of the efficacy of the two in treatment of postprandial hyperglycemia of newly-diagnosed type 2 diabetes (T2D) is investigated.Methods164 newly-diagnosed T2D patients with fasting plasma glucose (FPG) levels of 10 mmol/L (180 mg/dL) were consecutively alternated between acarbose- and repaglinide-treatment for 6 months.ResultsPer protocol analysis, 67% of acarbose-treated patients vs. 85% of repaglinide-treated patients achieved 2hPPG levels of
       
  • Reinterpreting renal hemodynamics: the importance of venous congestion and
           effective organ perfusion in acute kidney injury
    • Abstract: Publication date: Available online 23 January 2020Source: The American Journal of the Medical SciencesAuthor(s): Csaba Kopitkó, Tibor Gondos, Tibor Fülöp, László MedveAbstractThe significance of effective renal perfusion is relatively under-emphasized in the current literature. From a renal standpoint, not only cardiac output should be optimized but also the renal perfusion maximized. In the critical ill patients’ several additional variables, such as the intraabdominal pressure, the presence of venous congestion and elevated central venous pressures as well as airway pressures generated by mechanical ventilation do affect net renal perfusion. These forces represent both a potential danger and an ongoing opportunity to improve renal outcomes in the critically ill and an opportunity to move beyond the simplified viewpoint of optimizing volume status. Therefore, to optimize nephron-protective therapies, nephrologists and intensive care physicians should be familiar with the concept of net renal perfusion pressure. This review appraises the background literature on renal perfusion pressure, including the initial animal data and historical human studies up to the most current developments in the field, exploring potential avenues to assess and improve renal blood supply.
       
  • A fuller evaluation of the underlying causes of persistent iron deficiency
           anemia
    • Abstract: Publication date: Available online 23 January 2020Source: The American Journal of the Medical SciencesAuthor(s): Oscar M.P. Jolobe
       
  • Response: Letter to the Editor by Jolobe
    • Abstract: Publication date: Available online 23 January 2020Source: The American Journal of the Medical SciencesAuthor(s): Samuel Dickey, Don C. Rockey
       
  • Identification of hub genes and analysis of prognostic values in
           hepatocellular carcinoma by bioinformatics analysis
    • Abstract: Publication date: Available online 21 January 2020Source: The American Journal of the Medical SciencesAuthor(s): Liangfei Xu, Tong Tong, Ziran Wang, Yawen Qiang, Fan Ma, Xiaoling MaAbstractBackgroundHepatocellular carcinoma (HCC) is one of the most frequent cancers in the world. In this study, differentially expressed genes between tumor tissues and normal tissues were identified using the comprehensive analysis method in bioinformatics.MethodsWe downloaded three mRNA expression profiles from the Gene Expression Omnibus database (GEO) to identify differentially expressed genes (DEGs) between tumor tissues and adjacent normal tissues. The Gene Ontology, Kyoto Encyclopedia of Genes and Genomes pathway analysis, protein-protein interaction (PPI) network was performed to understand the function of DEGs. OncoLnc, which was linked to TCGA survival data, was used to investigate the prognostic values of hub genes. The expression of selected hub genes was validated by the quantitative real-time polymerase chain reaction (qRT-PCR).ResultsA total of 235 DEGs, consisting of 36 up-regulated and 199 down-regulated genes, were identified between tumor tissue and normal tissue. The GO and KEGG analysis results showed the up-regulated DEGs to be significantly enriched in cell division, mid-body, ATP binding, and oocyte meiosis pathways. The down-regulated DEGs were mainly involved in epoxygenase P450 pathway, extracellular region, oxidoreductase activity, and metabolic pathways. Ten hub genes, including AURKA, CDC20, FTCD, UBE2C, CCNB2, PTTG1, CDKN3, CKS1B, TOP2A, and KIF20A, were identified as the key genes in HCC. Survival analysis found the expression of hub genes to be significantly correlated with the survival of patients with HCC.ConclusionsThe present study identified hub genes and pathways in HCC that may be potential targets for diagnosis, treatment, and prognostic prediction.
       
  • Pulmonary artery pseudoaneurysm caused by lung abscess
    • Abstract: Publication date: Available online 16 January 2020Source: The American Journal of the Medical SciencesAuthor(s): Susumu Saito, Tsukasa Kadota, Mina Gochi
       
  • E-cigarettes and vaping associated lung injury: a case series and brief
           review
    • Abstract: Publication date: Available online 13 January 2020Source: The American Journal of the Medical SciencesAuthor(s): Robert Hilton, Ross Summer, Jesse Roman, Baskaran Sundaram, Gautam George
       
  • Exercise capacity and ventilatory efficiency in patients with pulmonary
           embolism after short duration of anticoagulation therapy
    • Abstract: Publication date: Available online 26 December 2019Source: The American Journal of the Medical SciencesAuthor(s): Dandan Huang, Jian Guo, Wenlan Yang, Jinming LiuAbstractBackgroundAlthough anticoagulation therapy can reduce the risk for pulmonary embolism (PE) recurrence, symptoms such as exertional dyspnea or pain can persist for several months to years. Therefore, we aimed to assess the improvement of ventilatory efficiency and exercise capacity during cardiopulmonary exercise test (CPET) in PE patients after short duration of anticoagulant therapy.MethodsPulmonary function testing (PFT), Arterial blood gas analysis (ABG) and CPET were performed in 30 PE patients after anticoagulant therapy of 4 weeks (early phase) and after 6 months (late phase). In addition, another thirty healthy volunteers underwent the same tests.ResultsPercentage of forced vital capacity (FVC %pred) improvement was evident in the PE group (P
       
  • Arterial Complications Associated with Renal Cell Carcinoma
    • Abstract: Publication date: Available online 24 December 2019Source: The American Journal of the Medical SciencesAuthor(s): Jack Hua, David Pointer, Jonathan Silberstein, Albert D. Sam
       
  • Different statin effects of ST-elevation versus non-ST-elevation acute
           myocardial infarction in Korean after stent implantation
    • Abstract: Publication date: Available online 7 December 2019Source: The American Journal of the Medical SciencesAuthor(s): Yong Hoon Kim, Ae-Young Her, Myung Ho Jeong, Byeong-Keuk Kim, Sung-Jin Hong, Seunghwan Kim, Chul-Min Ahn, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo JangABSTRACTBackgroundIntensive statin therapy reduces cardiovascular events in acute coronary syndrome. The data concerning the long-term clinical impacts of statin therapy between ST-segment elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI) after drug-eluting stents (DES) implantation are limited. We compared the 2-year clinical outcomes between these two groups after statin therapy.MethodsA total of 30616 Korean acute myocardial infarction (AMI) patients were enrolled. Among them, 13686 patients were classified as the group A (STEMI statin user), 3824 patients were as the group B (STEMI statin non-user), 10398 patients were as the group C (NSTEMI statin user), and 2708 patients were as the group D (NSTEMI statin non-user). The major clinical endpoint was the occurrence of major adverse cardiac events (MACE) defined as all-cause death, recurrent myocardial infarction (re-MI), and any repeat revascularization during a 2-year follow-up period.ResultsAfter adjustment, the cumulative risks of MACE (adjusted hazard ratio [aHR] = 1.112 [1.002-1.235]; P = 0.047), all-cause death (aHR = 1.271 [1.054-1.532]; P = 0.012), and target vessel revascularization (TVR, aHR = 1.262 [1.049-1.518]; P = 0.014) in the group C were significantly higher than group A. The cumulative risks of MACE, all-cause death, and cardiac death of the statin non-user group (group B and D) were significantly higher compared with statin user group (group A and C).ConclusionsStatin therapy was more effective in reducing the cumulative risks of MACE, all-cause death, and TVR in the STEMI group than NSTEMI group in Korean AMI patients after successful DES implantation.
       
 
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