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Publisher: Springer-Verlag   (Total: 2335 journals)

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Showing 1201 - 1400 of 2335 Journals sorted alphabetically
J. of Community Health     Hybrid Journal   (Followers: 8, SJR: 0.921, h-index: 44)
J. of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology     Hybrid Journal   (Followers: 7, SJR: 1.087, h-index: 74)
J. of Comparative Physiology B : Biochemical, Systemic, and Environmental Physiology     Hybrid Journal   (Followers: 4, SJR: 1.126, h-index: 59)
J. of Compassionate Health Care     Open Access   (Followers: 1)
J. of Computational Analysis and Applications     Hybrid Journal   (SJR: 0.291, h-index: 19)
J. of Computational Electronics     Hybrid Journal   (Followers: 4, SJR: 0.511, h-index: 20)
J. of Computational Neuroscience     Hybrid Journal   (Followers: 22, SJR: 1.068, h-index: 60)
J. of Computer and Systems Sciences Intl.     Hybrid Journal   (SJR: 0.27, h-index: 13)
J. of Computer Science and Technology     Open Access   (Followers: 5, SJR: 0.437, h-index: 31)
J. of Computer Virology and Hacking Techniques     Hybrid Journal   (Followers: 6, SJR: 0.151, h-index: 2)
J. of Computer-Aided Molecular Design     Hybrid Journal   (Followers: 3, SJR: 0.995, h-index: 78)
J. of Computers in Education     Hybrid Journal   (Followers: 8)
J. of Computing in Higher Education     Hybrid Journal   (Followers: 13, SJR: 0.363, h-index: 21)
J. of Consumer Policy     Hybrid Journal   (Followers: 5, SJR: 0.704, h-index: 30)
J. of Contemporary Mathematical Analysis     Hybrid Journal   (SJR: 0.237, h-index: 5)
J. of Contemporary Physics (Armenian Academy of Sciences)     Hybrid Journal   (Followers: 11, SJR: 0.197, h-index: 6)
J. of Contemporary Psychotherapy     Hybrid Journal   (Followers: 5, SJR: 0.397, h-index: 23)
J. of Control Theory and Applications     Hybrid Journal   (Followers: 2, SJR: 0.359, h-index: 19)
J. of Control, Automation and Electrical Systems     Hybrid Journal   (Followers: 7, SJR: 0.231, h-index: 9)
J. of Crop Science and Biotechnology     Hybrid Journal   (Followers: 7)
J. of Cross-Cultural Gerontology     Hybrid Journal   (Followers: 5, SJR: 0.631, h-index: 29)
J. of Cryptographic Engineering     Partially Free   (Followers: 5, SJR: 0.989, h-index: 11)
J. of Cryptology     Hybrid Journal   (Followers: 2, SJR: 1.443, h-index: 55)
J. of Cultural Economics     Hybrid Journal   (Followers: 4, SJR: 0.539, h-index: 29)
J. of Database Marketing & Customer Strategy Management     Hybrid Journal   (Followers: 8, SJR: 0.149, h-index: 8)
J. of Derivatives & Hedge Funds     Hybrid Journal   (Followers: 9, SJR: 0.114, h-index: 5)
J. of Developmental and Physical Disabilities     Hybrid Journal   (Followers: 8, SJR: 0.574, h-index: 29)
J. of Digital Imaging     Hybrid Journal   (Followers: 9, SJR: 0.578, h-index: 35)
J. of Direct Data and Digital Marketing Practice     Hybrid Journal   (Followers: 8, SJR: 0.154, h-index: 6)
J. of Dynamical and Control Systems     Hybrid Journal   (Followers: 2, SJR: 0.4, h-index: 26)
J. of Dynamics and Differential Equations     Hybrid Journal   (SJR: 1.418, h-index: 31)
J. of Earth Science     Hybrid Journal   (Followers: 8, SJR: 0.483, h-index: 16)
J. of Earth System Science     Open Access   (Followers: 43, SJR: 0.448, h-index: 32)
J. of East Asian Linguistics     Hybrid Journal   (Followers: 5, SJR: 0.537, h-index: 20)
J. of Echocardiography     Hybrid Journal   (Followers: 4, SJR: 0.22, h-index: 3)
J. of Economic Growth     Hybrid Journal   (Followers: 28, SJR: 3.273, h-index: 63)
J. of Economic Interaction and Coordination     Hybrid Journal   (SJR: 0.263, h-index: 12)
J. of Economics     Hybrid Journal   (Followers: 15, SJR: 0.418, h-index: 23)
J. of Economics and Finance     Hybrid Journal   (Followers: 6, SJR: 0.272, h-index: 19)
J. of Educational Change     Hybrid Journal   (Followers: 7, SJR: 0.961, h-index: 21)
J. of Elasticity     Hybrid Journal   (Followers: 5, SJR: 0.851, h-index: 45)
J. of Electroceramics     Hybrid Journal   (SJR: 0.577, h-index: 57)
J. of Electronic Materials     Hybrid Journal   (Followers: 3, SJR: 0.609, h-index: 75)
J. of Electronic Testing     Hybrid Journal   (Followers: 2, SJR: 0.372, h-index: 27)
J. of Electronics (China)     Hybrid Journal   (Followers: 4, SJR: 0.112, h-index: 9)
J. of Elementary Science Education     Hybrid Journal   (Followers: 8)
J. of Engineering Mathematics     Hybrid Journal   (SJR: 0.347, h-index: 37)
J. of Engineering Physics and Thermophysics     Hybrid Journal   (Followers: 1, SJR: 0.288, h-index: 11)
J. of Engineering Research     Open Access   (Followers: 1, SJR: 0.145, h-index: 5)
J. of Engineering Thermophysics     Hybrid Journal   (Followers: 2, SJR: 0.763, h-index: 9)
J. of Environmental Studies and Sciences     Partially Free   (Followers: 2)
J. of Ethology     Hybrid Journal   (Followers: 2, SJR: 0.609, h-index: 25)
J. of Evolution Equations     Hybrid Journal   (SJR: 0.826, h-index: 26)
J. of Evolutionary Biochemistry and Physiology     Hybrid Journal   (SJR: 0.145, h-index: 11)
J. of Evolutionary Economics     Hybrid Journal   (Followers: 8, SJR: 0.492, h-index: 52)
J. of Experimental and Theoretical Physics     Hybrid Journal   (Followers: 3, SJR: 0.458, h-index: 39)
J. of Experimental Criminology     Hybrid Journal   (Followers: 43, SJR: 1.445, h-index: 28)
J. of Failure Analysis and Prevention     Hybrid Journal   (Followers: 5, SJR: 0.261, h-index: 15)
J. of Family and Economic Issues     Hybrid Journal   (Followers: 6, SJR: 0.396, h-index: 32)
J. of Family Violence     Hybrid Journal   (Followers: 35, SJR: 0.639, h-index: 56)
J. of Financial Services Marketing     Hybrid Journal   (Followers: 3, SJR: 0.273, h-index: 10)
J. of Financial Services Research     Hybrid Journal   (Followers: 21, SJR: 0.572, h-index: 36)
J. of Fixed Point Theory and Applications     Hybrid Journal   (SJR: 0.644, h-index: 13)
J. of Fluorescence     Hybrid Journal   (Followers: 3, SJR: 0.465, h-index: 56)
J. of Food Measurement and Characterization     Hybrid Journal   (SJR: 0.307, h-index: 4)
J. of Food Science and Technology     Hybrid Journal   (Followers: 6, SJR: 0.441, h-index: 29)
J. of Forest Research     Hybrid Journal   (Followers: 3, SJR: 0.495, h-index: 27)
J. of Forestry Research     Hybrid Journal   (Followers: 6, SJR: 0.304, h-index: 14)
J. of Fourier Analysis and Applications     Hybrid Journal   (Followers: 1, SJR: 1.18, h-index: 42)
J. of Friction and Wear     Hybrid Journal   (Followers: 6, SJR: 0.373, h-index: 7)
J. of Fusion Energy     Hybrid Journal   (Followers: 3, SJR: 0.387, h-index: 19)
J. of Gambling Studies     Hybrid Journal   (Followers: 4, SJR: 1.171, h-index: 57)
J. of Gastroenterology     Hybrid Journal   (Followers: 11, SJR: 1.651, h-index: 88)
J. of Gastrointestinal Cancer     Hybrid Journal   (Followers: 3, SJR: 0.304, h-index: 39)
J. of Gastrointestinal Surgery     Hybrid Journal   (Followers: 6, SJR: 1.64, h-index: 99)
J. of General Internal Medicine     Hybrid Journal   (Followers: 15, SJR: 1.804, h-index: 134)
J. of General Plant Pathology     Hybrid Journal   (SJR: 0.554, h-index: 22)
J. of Genetic Counseling     Hybrid Journal   (Followers: 5, SJR: 0.902, h-index: 39)
J. of Genetics     Open Access   (Followers: 4, SJR: 0.458, h-index: 28)
J. of Geodesy     Hybrid Journal   (Followers: 8, SJR: 2.173, h-index: 56)
J. of Geographical Sciences     Hybrid Journal   (Followers: 1, SJR: 0.8, h-index: 23)
J. of Geographical Systems     Hybrid Journal   (Followers: 4, SJR: 0.822, h-index: 39)
J. of Geometric Analysis     Hybrid Journal   (SJR: 1.491, h-index: 27)
J. of Geometry     Hybrid Journal   (Followers: 1, SJR: 0.272, h-index: 15)
J. of Global Optimization     Hybrid Journal   (Followers: 4, SJR: 0.992, h-index: 60)
J. of Global Policy and Governance     Hybrid Journal   (Followers: 8)
J. of Grid Computing     Hybrid Journal   (SJR: 1.414, h-index: 37)
J. of Hand and Microsurgery     Hybrid Journal   (Followers: 1)
J. of Happiness Studies     Hybrid Journal   (Followers: 18, SJR: 0.881, h-index: 39)
J. of Hematopathology     Hybrid Journal   (Followers: 4, SJR: 0.2, h-index: 13)
J. of Heuristics     Hybrid Journal   (Followers: 5, SJR: 1.308, h-index: 50)
J. of High Energy Physics     Hybrid Journal   (Followers: 19, SJR: 1.052, h-index: 153)
J. of Homotopy and Related Structures     Hybrid Journal   (SJR: 0.232, h-index: 2)
J. of Housing and the Built Environment     Hybrid Journal   (Followers: 7, SJR: 0.648, h-index: 28)
J. of Huazhong University of Science and Technology [Medical Sciences]     Hybrid Journal   (SJR: 0.344, h-index: 19)
J. of Ichthyology     Hybrid Journal   (Followers: 3, SJR: 0.304, h-index: 10)
J. of Immigrant and Minority Health     Hybrid Journal   (Followers: 10, SJR: 0.759, h-index: 37)
J. of Inclusion Phenomena and Macrocyclic Chemistry     Hybrid Journal   (Followers: 1, SJR: 0.331, h-index: 46)
J. of Indian Philosophy     Hybrid Journal   (Followers: 11, SJR: 0.127, h-index: 12)
J. of Indian Prosthodontic Society     Open Access   (SJR: 0.164, h-index: 7)
J. of Industrial Microbiology and Biotechnology     Hybrid Journal   (Followers: 14, SJR: 0.966, h-index: 80)
J. of Industry, Competition and Trade     Hybrid Journal   (Followers: 8, SJR: 0.327, h-index: 15)
J. of Infection and Chemotherapy     Hybrid Journal   (Followers: 1, SJR: 0.673, h-index: 46)
J. of Information Technology     Hybrid Journal   (Followers: 52, SJR: 1.474, h-index: 55)
J. of Information Technology Teaching Cases     Hybrid Journal   (Followers: 8)
J. of Infrared, Millimeter and Terahertz Waves     Hybrid Journal   (Followers: 2, SJR: 1.25, h-index: 36)
J. of Inherited Metabolic Disease     Hybrid Journal   (Followers: 2, SJR: 1.389, h-index: 77)
J. of Inorganic and Organometallic Polymers and Materials     Partially Free   (Followers: 8, SJR: 0.338, h-index: 33)
J. of Insect Behavior     Hybrid Journal   (Followers: 9, SJR: 0.569, h-index: 39)
J. of Insect Conservation     Hybrid Journal   (Followers: 10, SJR: 0.872, h-index: 43)
J. of Intelligent and Robotic Systems     Hybrid Journal   (Followers: 2, SJR: 0.629, h-index: 43)
J. of Intelligent Information Systems     Hybrid Journal   (Followers: 1, SJR: 0.691, h-index: 43)
J. of Intelligent Manufacturing     Hybrid Journal   (Followers: 4, SJR: 1.397, h-index: 54)
J. of Interventional Cardiac Electrophysiology     Hybrid Journal   (SJR: 0.93, h-index: 43)
J. of Intl. Business Studies     Hybrid Journal   (Followers: 29, SJR: 4.208, h-index: 130)
J. of Intl. Entrepreneurship     Hybrid Journal   (Followers: 9, SJR: 0.549, h-index: 23)
J. of Intl. Migration and Integration / Revue de l integration et de la migration internationale     Hybrid Journal   (Followers: 12, SJR: 0.308, h-index: 13)
J. of Intl. Relations and Development     Hybrid Journal   (Followers: 20, SJR: 0.793, h-index: 22)
J. of Labor Research     Hybrid Journal   (Followers: 17, SJR: 0.394, h-index: 27)
J. of Logic, Language and Information     Hybrid Journal   (Followers: 7, SJR: 0.288, h-index: 25)
J. of Low Temperature Physics     Hybrid Journal   (Followers: 2, SJR: 0.531, h-index: 52)
J. of Machinery Manufacture and Reliability     Hybrid Journal   (Followers: 2, SJR: 0.203, h-index: 7)
J. of Mammalian Evolution     Hybrid Journal   (Followers: 5, SJR: 1.134, h-index: 37)
J. of Mammary Gland Biology and Neoplasia     Hybrid Journal   (Followers: 1, SJR: 2.252, h-index: 83)
J. of Management and Governance     Hybrid Journal   (Followers: 13, SJR: 0.805, h-index: 33)
J. of Management Control     Hybrid Journal   (Followers: 5, SJR: 0.605, h-index: 6)
J. of Marine Science and Application     Hybrid Journal   (Followers: 3, SJR: 0.439, h-index: 11)
J. of Marine Science and Technology     Hybrid Journal   (Followers: 3, SJR: 0.235, h-index: 19)
J. of Maritime Archaeology     Hybrid Journal   (Followers: 21, SJR: 0.228, h-index: 8)
J. of Market-Focused Management     Hybrid Journal   (Followers: 2)
J. of Marketing Analytics     Hybrid Journal   (Followers: 3)
J. of Material Cycles and Waste Management     Hybrid Journal   (Followers: 3, SJR: 0.449, h-index: 22)
J. of Materials Engineering and Performance     Hybrid Journal   (Followers: 22, SJR: 0.544, h-index: 40)
J. of Materials Science     Hybrid Journal   (Followers: 19, SJR: 0.836, h-index: 123)
J. of Materials Science : Materials in Electronics     Hybrid Journal   (Followers: 3)
J. of Materials Science : Materials in Medicine     Hybrid Journal   (Followers: 5)
J. of Mathematical Biology     Hybrid Journal   (Followers: 12, SJR: 1.011, h-index: 71)
J. of Mathematical Chemistry     Hybrid Journal   (Followers: 5, SJR: 0.497, h-index: 45)
J. of Mathematical Fluid Mechanics     Hybrid Journal   (Followers: 6, SJR: 1.22, h-index: 22)
J. of Mathematical Imaging and Vision     Hybrid Journal   (Followers: 4, SJR: 0.901, h-index: 53)
J. of Mathematical Modelling and Algorithms     Hybrid Journal   (Followers: 2, SJR: 0.414, h-index: 23)
J. of Mathematical Sciences     Hybrid Journal   (SJR: 0.272, h-index: 23)
J. of Mathematics Teacher Education     Hybrid Journal   (Followers: 14, SJR: 1.062, h-index: 20)
J. of Maxillofacial and Oral Surgery     Hybrid Journal   (Followers: 1)
J. of Mechanical Science and Technology     Hybrid Journal   (Followers: 5, SJR: 0.589, h-index: 26)
J. of Medical and Biological Engineering     Hybrid Journal   (Followers: 1, SJR: 0.387, h-index: 18)
J. of Medical Humanities     Hybrid Journal   (Followers: 22, SJR: 0.299, h-index: 18)
J. of Medical Systems     Hybrid Journal   (Followers: 1, SJR: 0.717, h-index: 44)
J. of Medical Toxicology     Hybrid Journal   (Followers: 4, SJR: 0.874, h-index: 28)
J. of Medical Ultrasonics     Hybrid Journal   (Followers: 2, SJR: 0.18, h-index: 13)
J. of Medicine and the Person     Hybrid Journal  
J. of Membrane Biology     Hybrid Journal   (Followers: 2, SJR: 0.738, h-index: 82)
J. of Micro-Bio Robotics     Hybrid Journal   (SJR: 0.28, h-index: 3)
J. of Microbiology     Hybrid Journal   (Followers: 7, SJR: 0.741, h-index: 43)
J. of Mining Science     Hybrid Journal   (Followers: 5, SJR: 0.317, h-index: 16)
J. of Molecular Evolution     Hybrid Journal   (Followers: 9, SJR: 0.952, h-index: 108)
J. of Molecular Histology     Hybrid Journal   (Followers: 2, SJR: 0.755, h-index: 48)
J. of Molecular Medicine     Hybrid Journal   (Followers: 15, SJR: 2.165, h-index: 113)
J. of Molecular Modeling     Hybrid Journal   (Followers: 4, SJR: 0.466, h-index: 50)
J. of Molecular Neuroscience     Partially Free   (Followers: 10, SJR: 0.988, h-index: 69)
J. of Mountain Science     Hybrid Journal   (Followers: 4, SJR: 0.418, h-index: 15)
J. of Muscle Research and Cell Motility     Hybrid Journal   (Followers: 1, SJR: 1.264, h-index: 55)
J. of Nanoparticle Research     Hybrid Journal   (Followers: 4, SJR: 0.583, h-index: 84)
J. of Natural Medicines     Hybrid Journal   (SJR: 0.602, h-index: 28)
J. of Near-Death Studies     Hybrid Journal   (Followers: 2)
J. of Nephrology     Hybrid Journal   (Followers: 5, SJR: 0.689, h-index: 55)
J. of Network and Systems Management     Hybrid Journal   (SJR: 0.466, h-index: 26)
J. of Neural Transmission     Hybrid Journal   (Followers: 2, SJR: 1.034, h-index: 86)
J. of Neuro-Oncology     Hybrid Journal   (Followers: 4, SJR: 1.274, h-index: 90)
J. of Neuroimmune Pharmacology     Hybrid Journal   (Followers: 1, SJR: 1.662, h-index: 45)
J. of Neurology     Hybrid Journal   (Followers: 13, SJR: 1.429, h-index: 105)
J. of NeuroVirology     Hybrid Journal   (Followers: 1, SJR: 0.979, h-index: 69)
J. of Nondestructive Evaluation     Hybrid Journal   (Followers: 9, SJR: 0.863, h-index: 27)
J. of Nonlinear Science     Hybrid Journal   (Followers: 1, SJR: 1.887, h-index: 42)
J. of Nonverbal Behavior     Hybrid Journal   (Followers: 4, SJR: 0.723, h-index: 47)
J. of Nuclear Cardiology     Hybrid Journal   (SJR: 1.024, h-index: 68)
J. of Nutrition, Health and Aging     Hybrid Journal   (Followers: 19, SJR: 0.919, h-index: 60)
J. of Obstetrics and Gynecology of India     Hybrid Journal   (Followers: 6, SJR: 0.214, h-index: 6)
J. of Occupational Rehabilitation     Hybrid Journal   (Followers: 16, SJR: 0.811, h-index: 51)
J. of Ocean Engineering and Marine Energy     Hybrid Journal   (Followers: 1)
J. of Ocean University of China (English Edition)     Hybrid Journal   (Followers: 1, SJR: 0.237, h-index: 11)
J. of Oceanography     Hybrid Journal   (Followers: 10, SJR: 0.796, h-index: 52)
J. of Ocular Biology, Diseases, and Informatics     Hybrid Journal   (SJR: 0.183, h-index: 11)
J. of Optical and Fiber Communications Reports     Hybrid Journal   (Followers: 3)
J. of Optics     Hybrid Journal   (Followers: 8, SJR: 0.214, h-index: 8)
J. of Optimization Theory and Applications     Hybrid Journal   (Followers: 4, SJR: 0.898, h-index: 65)
J. of Ornithology     Hybrid Journal   (Followers: 21)
J. of Orofacial Orthopedics / Fortschritte der Kieferorthopädie     Hybrid Journal   (SJR: 0.574, h-index: 33)
J. of Orthopaedic Science     Hybrid Journal   (Followers: 5, SJR: 0.708, h-index: 48)
J. of Paleolimnology     Hybrid Journal   (Followers: 5, SJR: 0.984, h-index: 64)
J. of Parasitic Diseases     Hybrid Journal   (Followers: 2, SJR: 0.298, h-index: 9)
J. of Pediatric Neuropsychology     Hybrid Journal   (Followers: 3)
J. of Pest Science     Hybrid Journal   (Followers: 2, SJR: 1.341, h-index: 28)
J. of Pharmaceutical Health Care and Sciences     Open Access  
J. of Pharmaceutical Innovation     Hybrid Journal   (Followers: 8, SJR: 0.524, h-index: 17)
J. of Pharmaceutical Investigation     Hybrid Journal   (Followers: 1, SJR: 0.331, h-index: 6)
J. of Pharmacokinetics and Pharmacodynamics     Hybrid Journal   (Followers: 18, SJR: 0.708, h-index: 46)
J. of Phase Equilibria and Diffusion     Hybrid Journal   (Followers: 18, SJR: 0.433, h-index: 36)
J. of Philosophical Logic     Hybrid Journal   (Followers: 8, SJR: 0.704, h-index: 26)
J. of Physiology and Biochemistry     Hybrid Journal   (Followers: 3, SJR: 0.87, h-index: 33)

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Journal Cover European Surgery
  [SJR: 0.171]   [H-I: 15]   [5 followers]  Follow
    
   Hybrid Journal Hybrid journal (It can contain Open Access articles)
   ISSN (Print) 1682-4016 - ISSN (Online) 1682-8631
   Published by Springer-Verlag Homepage  [2335 journals]
  • Experimental nerve transfer model in the rat forelimb
    • Authors: K. D. Bergmeister; M. Aman; O. Riedl; K. Manzano-Szalai; M. E. Sporer; S. Salminger; O. C. Aszmann
      Pages: 334 - 341
      Abstract: Summary Background Nerve transfers are a powerful tool in extremity reconstruction, but the neurophysiological effects have not been adequately investigated. As 81 % of nerve injuries and most nerve transfers occur in the upper extremity with its own neurophysiological properties, the standard rat hindlimb model may not be optimal in this paradigm. Here we present an experimental rat forelimb model to investigate nerve transfers. Methods In ten male Sprague-Dawley rats, the ulnar nerve was transferred to the motor branch of long head of the biceps. Sham surgery was performed in five animals (exposure/closure). After 12 weeks of regeneration, muscle force and Bertelli test were performed and evaluated. Results The nerve transfer successfully reinnervated the long head of the biceps in all animals, as indicated by muscle force and behavioral outcome. No aberrant reinnervation occurred from the original motor source. Muscle force was 2,68 N ± 0.35 for the nerve transfer group and 2,85 N ± 0.39 for the sham group, which was not statically different (p = 0.436). The procedure led to minor functional deficits due to the loss of ulnar nerve function; this, however, could not be quantified with any of the presented measures. Conclusion The above-described rat model demonstrated a constant anatomy, suitable for nerve transfers that are accessible to standard neuromuscular analyses and behavioral testing. This model allows the study of both neurophysiologic properties and cognitive motor function after nerve transfers in the upper extremity.
      PubDate: 2016-12-01
      DOI: 10.1007/s10353-016-0386-4
      Issue No: Vol. 48, No. 6 (2016)
       
  • Surgical approach is superior to palliative treatment
           in oligometastatic lung cancer
    • Authors: Till Plönes; Alberto Lopez-Pastorini; Erich Stoelben
      Pages: 342 - 346
      Abstract: Summary Background The majority of patients with lung cancer are diagnosed in a metastatic state, in which prognosis is rather poor. Chemotherapy can improve median overall survival by only a few months, but a small percentage of these patients suffer only from oligometastatic diseases and may therefore be treated with curative intend. In this study, we compared two groups of patients with oligometastatic lung cancer, who received palliative treatment or multimodal treatment with a surgical approach. Methods We conducted a retrospective review of all patients with synchronous extrapulmonary oligometastatic disease diagnosed between 2010 and 2013. All data were extracted from the medical database of our department and further analysed. Results There were 52 patients diagnosed with oligometastatic lung cancer between 2010 and 2013. A cohort of 32 patients was treated surgically in a multimodal approach, but 19 patients refused surgery. These patients were treated by palliative chemotherapy or other palliative treatments, such as radiochemotherapy etc. Median overall survival was 18 months in the surgically treated group and 6 months in the palliative group (p < 0.001). In the surgically treated group, survival was correlated to pathologic T stage (pT1 29 months, pT2 13 months and pT3 13 months median overall survival, p < 0.05) and lymph node involvement (with mediastinal lymph node involvement 13 months and without mediastinal lymph node involvement 28 months median overall survival). Conclusion We conclude that surgery may have a beneficial effect in multimodal treatment of oligometastatic lung cancer. A prospective randomized study is necessary and may be feasible.
      PubDate: 2016-12-01
      DOI: 10.1007/s10353-016-0437-x
      Issue No: Vol. 48, No. 6 (2016)
       
  • Missed injuries in patients with abdominal gunshot trauma: risk factors
           and mortality rates
    • Authors: M. Ugur; S. Akkucuk; Y. S. Koca; C. Oruc; A. Aydogan
      Pages: 347 - 351
      Abstract: Introduction The aim of this study was to investigate the incidence, risk factors, and mortality rates of injuries missed during laparotomy in patients with high-kinetic energy gunshot trauma. Methods The retrospective study included 20 patients who underwent relaparotomy due to high-kinetic energy gunshot trauma at our hospital between 2010 and 2015. Mechanism of injury, time between initial laparotomy and relaparotomy, the method of incision used for laparotomy during the initial laparotomy, the organs detected with missed injury, and the mortality rates were recorded. Results All the patients were male, with a mean age of 24.90 ± 5.2 years. Missed injuries were markedly more common in the patients who underwent incomplete incision during the initial laparotomy (p < 0.05). Mortality occurred in 11 (55 %) patients. In these patients, time between laparotomy and relaparotomy was longer and the Injury Severity Score (ISS) was significantly higher compared to other patients (p < 0.05). Discussion A complete midline incision allowing optimal exposure should be performed in patients with penetrating abdominal trauma caused by high-kinetic energy gunshot. A systematic surgical exploration should be performed, including meticulous inspection of all the intraabdominal and retroperitoneal organs. Conclusion Damage control surgery (DCS) should be performed in patients with severe trauma and hemodynamic instability. Proper administration of DCS may lead to reduced incidence of missed injuries and thus may decrease the mortality rates.
      PubDate: 2016-12-01
      DOI: 10.1007/s10353-016-0411-7
      Issue No: Vol. 48, No. 6 (2016)
       
  • The importance of diagnostic awareness of groove pancreatitis
    • Authors: Erkan Oymaci; Serdar Akdoğan; Nurettin Kahramansoy; Ahmet Deniz Uçar; Savaş Yakan; Ayvaz Ulaş Urgancı; Özgür Esen Sipahi; Nazif Erkan; Mehmet Yildirim
      Pages: 357 - 360
      Abstract: Summary Background Groove pancreatitis is a form of focal chronic pancreatitis in the pancreatic tissue between the duodenal wall and the intrapancreatic portion of the common bile duct. Groove pancreatitis, paraduodenal pancreatitis, and duodenal dystrophy are regarded as synonyms by some authors whereas others use the term duodenal dystrophy. We aimed to review this rare entity and discuss its clinical features, diagnosis, and therapy. Methods We present a series of three cases of groove pancreatitis diagnosed at a tertiary medical center with a detailed review of the current medical literature. Results All patient were treated with conservative medical therapy, which consists of spasmolytic and analgesic therapy as well as antibiotic and enteral nutrition during hospitalization. Endoscopic drainage with endoscopic retrograde cholangiopancreatography (ERCP) was performed for two patients. No complications were observed after the ERCP procedure. Conclusion Groove pancreatitis can simulate, mask, or coexist with pancreatic carcinoma and it can be difficult to differentiate from adenocarcinoma. Clinical, radiological, and histological features may be helpful in making the differential diagnosis and should be keep in mind in the differential diagnosis of pancreatic head masses or duodenal wall stenosis.
      PubDate: 2016-12-01
      DOI: 10.1007/s10353-016-0424-2
      Issue No: Vol. 48, No. 6 (2016)
       
  • Role of needle core biopsy in patients presenting with a breast lump
           associated with trauma
    • Authors: M. A. Parvaiz; C. Richardson; B. Isgar
      Pages: 285 - 289
      Abstract: Summary Background Patients often present to the breast clinic with a lump following trauma to the breast. Routinely, triple assessment is performed on such patients. We investigated whether a proportion of them can be safely diagnosed on the basis of clinical and radiological assessment without the need for histological confirmation. Methods We prospectively assessed all patients with a history of trauma presenting to the breast clinic over a 5-year period. Results We included 135 patients, constituting 1 % of total patients seen. They were divided into two groups for analysis. Group A included patients with trauma-related pathologies (n = 70, 52 %), comprising 47 haematomas and 23 fat necrosis. This group had a higher proportion of anti-coagulant usage (20/70). Owing to concordant clinical and radiological benign features, core biopsy was only carried out in 16 cases (23 %). All patients in this group were followed up to confirm clinical and radiological resolution of findings with no case of delayed cancer diagnosis. Group B included patients with incidental pathologies (n = 65, 48 %), consisting of 23 cancers and 42 benign lesions. Comparatively fewer patients (13/65) were on anti-coagulants. They had a history of minimal trauma and mostly no bruising, but found a lump on self-examination. The 23 cancer patients in this group had prompt triple assessment and no delay in cancer treatment. Conclusion Triple assessment is vital in patients with suspicious clinical or radiological breast lesions. However, a core biopsy can be avoided in patients with a clear history of trauma with concordant clinical and radiological features and follow-up confirming complete resolution of findings.
      PubDate: 2016-10-01
      DOI: 10.1007/s10353-016-0425-1
      Issue No: Vol. 48, No. 5 (2016)
       
  • Esophagectomy for eosinophilic esophagitis: how to avoid it
    • Authors: Alfredo J Lucendo
      Pages: 318 - 319
      Abstract: Summary Patients with eosinophilic esophagitis (EoE) can currently benefit from an evidence-based medical and dietary treatment according to knowledge accumulated from observational studies and randomized controlled trials, the results of which were summarized in several systematic reviews and meta-analyses. Surgery is relegated to solving some uncommon complications of EoE and has been exclusively applied in a handful of cases of esophageal perforation. This letter to the editor criticizes the only case of elective esophagectomy carried out in a 27-year-old male with EoE and longstanding dysphagia, which was unresponsive to obstinate endoscopy-based treatment. Despite medical and dietary treatment, strategies in EoE must still be improved and basing the clinical management of sufferers on the application of therapies with demonstrated effectiveness instead of empirical strategies is highly desirable.
      PubDate: 2016-10-01
      DOI: 10.1007/s10353-016-0441-1
      Issue No: Vol. 48, No. 5 (2016)
       
  • Surgery of acute severe ulcerative colitis. Subtotal colectomy: when and
           how to do it'
    • Authors: Rosario Fornaro; Elisa Caratto; Michela Caratto; Camilla Sticchi; Alexander Salerno; Rita Bianchi; Stefano Scabini; Marco Casaccia
      Abstract: Summary Purpose The aim of this review is to focus attention on the role of surgery in the management of acute ulcerative colitis (UC). UC is a chronic inflammatory disease of the mucosa of the large intestine. Methods We have examined the data from the literature of the past 20 years and we have analyzed the role of emergency surgery. A medical literature search was conducted using Medline, Embase, Ovid Journals, and Science Direct. Results Acute severe colitis (ASC) occurs in 12–25% of patients affected by UC. Patients with ASC should be managed by a multidisciplinary team. Aggressive medical or surgical treatment is undertaken with the final aim of reducing mortality. Intravenous corticosteroids are the mainstay of therapy. Medical rescue therapy based on cyclosporine or infliximab should be considered if there is no response to corticosteroids after 3 days. In the event that there has been no response to medical rescue therapy after 4–7 days, the patient must undergo urgent colectomy surgery. Prolonged observation is counterproductive as over time it increases the risk of toxic megacolon and of perforation burdened with a very high mortality rate. Conclusions The best possible treatment is represented by subtotal colectomy with ileostomy and preservation of a long rectal stump. Emergency colectomy is characterized by high morbidity and low mortality rates.
      PubDate: 2016-12-22
      DOI: 10.1007/s10353-016-0458-5
       
  • Oxidative stress and angiogenesis in primary hyperparathyroidism
    • Authors: Mariusz Deska; Ewa Romuk; Oliwia Anna Segiet; Grzegorz Buła; Witold Truchanowski; Dominika Stolecka; Ewa Birkner; Jacek Gawrychowski
      Abstract: Summary Background The inappropriate elevation of parathormone (PTH), which regulates the process of angiogenesis in parathyroid tissue, causes the changes of activity of enzymes responsible for the removal of free radicals. Parathyroidectomy (PTX) in patients with primary hyperparathyroidism (PHPT) lowers the level of PTH and leads to the reduction of risk of cardiovascular and all-cause mortality by normalization of the antioxidant status. Therefore, the aims of the study were to assess the activity of antioxidant enzymes and free radical reaction products in patients after parathyroidectomy, and to evaluate the correlation between the systemic oxidative stress and angiogenic parameters. Materials and methods Patients with PHPT treated surgically were enrolled into the study. Total antioxidant capacity (TAC), total oxidative status (TOS), oxidative stress index (OSI), superoxide dismutase (SOD), ceruloplasmin (CER), lipid hydroperoxides (LHP) and malondialdehyde (MDA) were measured before and after parathyroidectomy. The immunohistological expression of angiogenic factors in parathyroid specimens was assessed by the BrightVision method from ImmunoLogic using murine monoclonal anti-human: anti-VEGF, anti-CD31 and anti-CD106 antibodies. Results The significant increase of TAC, CER, reduction of TOS, MDA, SOD, especially for cytoplasmic form, and significant decrease of OSI, LHP were observed after PTX. There was no significant correlation between changes of oxidative stress markers and angiogenic parameters: VEGF, CD-31, CD-106 in parathyroid tissue. The correlation level was low and medium. Conclusions Parathyroidectomy causes down-regulation of lipid peroxidation processes and leads to reduction of oxidative stress in patients with PHPT. The decrease in the OSI is the results of down-regulation of oxidative stress in the postoperative period. The change of the antioxidant status has no impact on angiogenesis processes in parathyroid tissue.
      PubDate: 2016-12-14
      DOI: 10.1007/s10353-016-0457-6
       
  • Marfan syndrome presenting with abdominal aortic aneurysm during pregnancy
    • Authors: J. Pasternak; M. Kaćanski; N. Budakov
      Abstract: Summary Methods We report a case of successfully performed Caesarean section followed by reconstruction of the abdominal aorta in a patient with Marfan syndrome. Results A 35-year-old woman at 37 weeks’ gestation in her second pregnancy was referred with abdominal aortic aneurysm. On admission she was asymptomatic, haemodynamically stable, and without clinical and radiological signs of rupture. Magnetic resonance imaging confirmed that the infrarenal aortic aneurysm continued to the right common iliac artery. Following preoperative assessment, it was decided to finalize gestation and reconstruct the aorta in a one-stage procedure. After a median xyphopubic laparotomy, Mizgav–Ladach Caesarean section and Pomeroy tubal sterilization were performed, followed by aneurysmectomy and aorto-bilateral iliac artery bypass. The postoperative course was uneventful. Both mother and child were doing well at follow-up 3, 9 and 12 months after the intervention. Conclusion To the best of our knowledge, this is the first case of true abdominal aortic aneurysm repair and Caesarean section as a one-stage procedure.
      PubDate: 2016-12-08
      DOI: 10.1007/s10353-016-0456-7
       
  • Perioperative fluid management
    • Authors: Martin W. Dünser; Arthur Kwizera
      PubDate: 2016-12-01
      DOI: 10.1007/s10353-016-0455-8
       
  • Bariatrische Eingriffe in der Therapie des Diabetes mellitus Typ II
    • Authors: Stephan Kriwanek; Nada Loibner; Philipp Patri; Mathias Hofmann
      Abstract: Zusammenfassung Mithilfe bariatrischer Eingriffe kann der adipositasassoziierte Diabetes mellitus Typ II günstig beeinflusst werden. Der antidiabetische Effekt ist durch eine Erhöhung der Insulinsensitivität bedingt. Ausmaß und Dauer der Remission hängen wesentlich von dem Schweregrad und der Dauer des Diabetes zum Zeitpunkt der Operation ab. Am meisten profitieren adipöse Patientinnen und Patienten mit einem Prädiabetes. Bariatrische Eingriffe sind bei massiv adipösen Diabetikern wirksamer als nichtoperative Verfahren.
      PubDate: 2016-11-28
      DOI: 10.1007/s10353-016-0446-9
       
  • Effect of different doses of 2‑aminoethoxydiphenyl borate on intestinal
           ischemia-reperfusion injury
    • Authors: Murat Basbug; Murat Yildar; İsmail Yaman; Faruk Cavdar; Ömer Faruk Özkan; Hasan Aksit; Musa Ozgür Ozyigit; Figen Aslan; Hayrullah Derici
      Abstract: Summary Background Acute mesenteric ischemia is a life-threatening clinical entity. 2‑Aminoethoxydiphenyl borate (2-APB) is a membrane-permeable modulator of intracellular inositol triphosphate-induced calcium release. We investigated the effects of different 2‑APB doses on intestinal ischemia-reperfusion injury in an experimental rat model. Methods We divided 24 Wistar albino rats into four groups: sham, control, ischemia-reperfusion +2 mg/kg 2‑APB, and ischemia-reperfusion +4 mg/kg 2‑APB. The sham group only underwent laparotomy for 1 h 30 min. A 30-min period of mesenteric ischemia was induced in the control and two treatment groups, followed by 1 h of reperfusion. Before the laparotomy, 2 mg/kg and 4 mg/kg 2‑APB was administered i.v. in the treatments groups, and blood samples were collected after reperfusion. Serum levels of malondialdehyde, superoxide dismutase, glutathione, total antioxidant capacity, tumor necrosis factor (TNF)-α, and interleukin-6 were analyzed. Intestinal tissues were taken for histopathological, DNA fragmentation, and terminal deoxynucleotidyl transferase dUTP nick end labeling analyses to determine the proportion of apoptotic cells. Results 2-APB reduced serum malondialdehyde, TNF-α, and interleukin-6 levels. However, superoxide dismutase and total antioxidant capacity levels increased significantly in the 4‑mg/kg 2‑APB group (p < 0.05). The intestinal histopathological injury scores were significantly higher in the control group; these injuries were prevented in the 4‑mg/kg 2‑APB dose group. DNA damage after ischemia-perfusion decreased significantly in the 4‑mg/kg 2‑APB group compared with the control group. Conclusion 2-APB decreases oxidative stress and cell injury. Administering 4 mg/kg 2‑APB prevented ischemia-perfusion injury by diminishing histological damage.
      PubDate: 2016-11-16
      DOI: 10.1007/s10353-016-0452-y
       
  • A method for shaping a smooth gastric tube
    • Authors: Masahiro Kimura; Hideyuki Ishiguro; Tatsuya Tanaka; Kouji Mizoguchi
      Abstract: Summary Background The quality of the gastric tube commonly used for reconstruction after esophagectomy can influence postoperative progress. Moreover, formation of a gastric tube cannot generally be re-performed. To create a smooth gastric tube, various devices and two or more staplers are used; the use of two or more staplers means that an intersection exists. The intersection is inherently weak, and needs reinforcement as a potential site of leakage. Methods To verify the optimal orientation relative to the previous stapler, we experimented using the stomach of a pig. Difficulty was encountered inserting the stapler when orientation relative to the previous stapler was changed. The shape of the gastric wall and the staples after firing were observed. Results The intersection of the first and second staplers is complicated as the angle increases and the modification required to the stomach also increases. In the part that is not an intersection, almost all of the staples had a perfect form. At 0°, half of the staples had perfect forms, but the remaining half of the staples were distorted in shape. At 90°, none of the staples had perfect shape. Insertion of the stapler was easy and little modification of the stomach wall was needed with the radial stapler. Conclusion Herein we describe some to note at the time of gastric tube creation and our technique for the formation of a well-shaped gastric tube in which the unstapled intersection seems to maintain a natural curve and is not prone to leakage. The use of a radial stapler, in addition to a linear stapler, is a very useful and safe method for the formation of the gastric tube.
      PubDate: 2016-11-16
      DOI: 10.1007/s10353-016-0454-9
       
  • Erratum to: Surgical approach is superior to palliative treatment in
           oligometastatic lung cancer
    • Authors: Till Ploenes; Alberto Lopez-Pastorini; Erich Stoelben
      PubDate: 2016-11-10
      DOI: 10.1007/s10353-016-0445-x
       
  • Seasonal surgery: acting at dawn
    • PubDate: 2016-11-02
      DOI: 10.1007/s10353-016-0453-x
       
  • A novel glue device for fixation of mesh and peritoneal closure during
           laparoscopic inguinal hernia repair: short- and medium-term results
    • Authors: Bernhard Dauser; Alexander Szyszkowitz; Gerald Seitinger; René H. Fortelny; Friedrich Herbst
      Abstract: Summary Background Mesh fixation during transabdominal preperitoneal (TAPP) hernia repair should be done using nonpenetrating fixation devices in order to reduce acute and chronic pain. Beside fibrin sealant, N‑butyl cyanoacrylate (NBCA) can be applied. However, there are limited data using NBCA exclusively for fixation of mesh and closure of peritoneum following TAPP repair. We therefore studied a novel laparoscopic fixation device (LiquiBand®Fix8™ by Advanced Medical Solutions, Plymouth, UK) addressing these issues. Methods A prospective study was performed in two (different tertiary referral) centres in Austria, including patients undergoing TAPP repair between January and May 2015. The aforementioned device was used for fixation of mesh at predefined reference points (rectus muscle, pubic bone, triangle of doom, triangle of pain) and entire closure of peritoneum whenever possible. Results In a total of 34 (4 female) patients, 40 inguinal hernias were repaired using the TAPP approach. Fixation of mesh at four predefined reference points was successful using a single liquid anchor in 88.1 % (141/160). Thorough closure of peritoneum using NBCA was possible in 36 cases (90.0 %). Twice, additional suturing was done as the device clogged during this step of procedure. Finally, in another 2 patients, the attending surgeon declined using glue at all, as the sigmoid colon attached exerted too much traction. No device-related complication was recorded during 1‑year follow-up. Conclusion Nonpenetrating fixation of mesh during TAPP repair using this novel device is highly effective. In addition, closure of peritoneum using exclusively NBCA is safe and feasible according to our experience
      PubDate: 2016-10-21
      DOI: 10.1007/s10353-016-0450-0
       
  • Viability of five different pre- and intraoperative imaging methods for
           autologous breast reconstruction
    • Authors: K. F. Schrögendorfer; S. Nickl; M. Keck; D. B. Lumenta; C. Loewe; M. Gschwandtner; W. Haslik; J. Nedomansky
      Abstract: Summary Background Autologous breast reconstruction is an integral part in the treatment of breast cancer. While computed tomography angiography (CTA) is an established preoperative diagnostic tool for microsurgeons, no study has so far evaluated and compared five different imaging methods and their value for the reconstructive team. In order to determine the feasibility of each of the tools for routine or specialized diagnostic application, the methods’ efficiency and informative value were analyzed. Methods We retrospectively analyzed imaging data of 41 patients used for perforator location and assessment for regional perfusion and vessel patency in patients undergoing autologous breast reconstruction with deep inferior epigastric perforator flap (DIEP), transverse rectus abdominis muscle flap (TRAM), or transverse myocutaneous gracilis flap (TMG). Five different imaging techniques were used: hand held Doppler (HHD), CT angiography (CTA), macroscopic indocyanine green (ICG) video angiography, microscope-integrated ICG video angiography, and laser Doppler imaging (LDI). Results CTA proved to be the best tool for preoperative determination of the highly variable anatomy of the abdominal region, whereas HHD showed the same information on perforator localization with some false-positive results. Intraoperative HHD was an excellent tool for dissection and vessel patency judgment. Microscope-integrated ICG was an excellent tool to document the patency of microanastomoses. In our series, macroscopic perfusion measurement with ICG or LDI was only justified in special situations, where information on perfusion of abdominal or mastectomy flaps was required. LDI did not add any additional information. Conclusion Preoperative assessment should be performed by CTA with verification of the perforator location by HHD. Intraoperative HHD and microscope-integrated ICG contribute most toward the evaluation of vessel patency. ICG and LDI should only be used for special indications.
      PubDate: 2016-10-19
      DOI: 10.1007/s10353-016-0449-6
       
  • Cystic tumors of the pancreas
    • Authors: Thomas Sautner
      PubDate: 2016-10-11
      DOI: 10.1007/s10353-016-0448-7
       
  • Programmed death-ligand 1 expression in rectal cancer
    • Authors: G. Jomrich; G. R. Silberhumer; B. Marian; A. Beer; L. Müllauer
      Abstract: Summary Background Colorectal cancer (CRC) is the fourth most common cause of death worldwide. Approximately 30 % of all CRC occurs in the rectum. Improvements in survival rates were achieved thanks to multimodal therapy, combining surgery and chemoradiation. Nevertheless, the prognosis of patients suffering from rectal cancer (RC) remains poor. Programmed cell death protein 1 (PD-1) and its ligand programmed death ligand 1 (PD-L1) regulate tumor immune response. The aim of this study was to analyze the expression of PD-L1 in RC pre- and post-neoadjuvant therapy and evaluate PD-L1 as a biomarker and potential target for therapy. Methods In all, 29 patients with RC treated at the Medical University Vienna who received preoperative chemoradiation were retrospectively enrolled in this study. Expression of PD-L1 was investigated by immunohistochemistry with two different anti-PD-L1 antibodies. Results No PD-L1 expression on cancer cells could be observed in all 29 cases in the specimens before chemoradiation as well as in the surgical specimens after neoadjuvant therapy. In one of the two staining methods performed, five (17.24 %) post-chemoradiation cases showed faint lymphohistiocytic staining. Conclusion No expression of PD-L1 in RC cells before and after chemoradiation was found in our collective of 29 patients. Further investigations to evaluate the role of PD-L1 as a potential therapeutic target in RC are urgently needed.
      PubDate: 2016-10-07
      DOI: 10.1007/s10353-016-0447-8
       
  • Celiac artery compression of patients undergoing pancreatic surgery
           – a case series
    • Authors: A. Pötscher; F. Längle
      Abstract: Summary Background Celiac artery compression due to the median arcuate ligament is a rare but not an uncommon finding in patients undergoing pancreaticoduodenectomy (PD). Due to the interruption of the collateral pathways during surgery, celiac artery compression may be associated with fatal complications. Case reports In this paper, we present three patients with celiac artery compression undergoing PD. In the first case, celiac artery compression was recognized during surgery, but nevertheless the patient died postoperatively because of ongoing Klebsiella sepsis. In the second case, we did not recognize it during initial surgery so further complications could have been avoided. In the third case, compression was detected during PD and the postoperative course was without complications. Conclusion Preoperative abdominal CT scan should be evaluated very carefully in order to identify celiac artery compression. Otherwise absence or limitation of blood flow within the common hepatic artery (CHA) during surgery should lead surgeon to suspect presence of compression of the celiac artery.
      PubDate: 2016-09-15
      DOI: 10.1007/s10353-016-0443-z
       
 
 
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