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Publisher: Springer-Verlag   (Total: 2341 journals)

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Showing 1 - 200 of 2341 Journals sorted alphabetically
3D Research     Hybrid Journal   (Followers: 19, SJR: 0.214, h-index: 10)
4OR: A Quarterly J. of Operations Research     Hybrid Journal   (Followers: 9, SJR: 1.073, h-index: 25)
AAPS J.     Hybrid Journal   (Followers: 17, SJR: 1.192, h-index: 74)
AAPS PharmSciTech     Hybrid Journal   (Followers: 6, SJR: 0.718, h-index: 54)
Abdominal Imaging     Hybrid Journal   (Followers: 16, SJR: 0.723, h-index: 60)
Abhandlungen aus dem Mathematischen Seminar der Universitat Hamburg     Hybrid Journal   (Followers: 2, SJR: 0.447, h-index: 12)
Academic Psychiatry     Full-text available via subscription   (Followers: 22, SJR: 0.492, h-index: 32)
Academic Questions     Hybrid Journal   (Followers: 7, SJR: 0.135, h-index: 6)
Accreditation and Quality Assurance: J. for Quality, Comparability and Reliability in Chemical Measurement     Hybrid Journal   (Followers: 26, SJR: 0.378, h-index: 30)
Acoustical Physics     Hybrid Journal   (Followers: 10, SJR: 0.355, h-index: 20)
Acoustics Australia     Hybrid Journal  
Acta Analytica     Hybrid Journal   (Followers: 7, SJR: 0.387, h-index: 6)
Acta Applicandae Mathematicae     Hybrid Journal   (Followers: 1, SJR: 0.624, h-index: 34)
Acta Biotheoretica     Hybrid Journal   (Followers: 5, SJR: 0.419, h-index: 25)
Acta Diabetologica     Hybrid Journal   (Followers: 12, SJR: 1.318, h-index: 46)
Acta Endoscopica     Hybrid Journal   (Followers: 1, SJR: 0.113, h-index: 8)
acta ethologica     Hybrid Journal   (Followers: 4, SJR: 0.465, h-index: 23)
Acta Geochimica     Hybrid Journal   (Followers: 3)
Acta Geodaetica et Geophysica     Hybrid Journal   (Followers: 1, SJR: 0.294, h-index: 13)
Acta Geotechnica     Hybrid Journal   (Followers: 6, SJR: 1.818, h-index: 22)
Acta Informatica     Hybrid Journal   (Followers: 5, SJR: 0.524, h-index: 32)
Acta Mathematica     Hybrid Journal   (Followers: 10, SJR: 8.021, h-index: 47)
Acta Mathematica Hungarica     Hybrid Journal   (Followers: 2, SJR: 0.53, h-index: 29)
Acta Mathematica Sinica, English Series     Hybrid Journal   (Followers: 5, SJR: 0.406, h-index: 30)
Acta Mathematica Vietnamica     Hybrid Journal   (SJR: 0.451, h-index: 5)
Acta Mathematicae Applicatae Sinica, English Series     Hybrid Journal   (SJR: 0.22, h-index: 20)
Acta Mechanica     Hybrid Journal   (Followers: 18, SJR: 0.898, h-index: 52)
Acta Mechanica Sinica     Hybrid Journal   (Followers: 4, SJR: 0.426, h-index: 29)
Acta Metallurgica Sinica (English Letters)     Hybrid Journal   (Followers: 5, SJR: 0.525, h-index: 18)
Acta Meteorologica Sinica     Hybrid Journal   (Followers: 3, SJR: 0.524, h-index: 14)
Acta Neurochirurgica     Hybrid Journal   (Followers: 6, SJR: 0.833, h-index: 73)
Acta Neurologica Belgica     Hybrid Journal   (SJR: 0.348, h-index: 27)
Acta Neuropathologica     Hybrid Journal   (Followers: 3, SJR: 6.61, h-index: 117)
Acta Oceanologica Sinica     Hybrid Journal   (Followers: 3, SJR: 0.295, h-index: 17)
Acta Parasitologica     Hybrid Journal   (Followers: 9, SJR: 0.581, h-index: 28)
Acta Physiologiae Plantarum     Hybrid Journal   (Followers: 2, SJR: 0.551, h-index: 39)
Acta Politica     Hybrid Journal   (Followers: 13, SJR: 0.658, h-index: 20)
adhäsion KLEBEN & DICHTEN     Hybrid Journal   (Followers: 5, SJR: 0.103, h-index: 4)
ADHD Attention Deficit and Hyperactivity Disorders     Hybrid Journal   (Followers: 20, SJR: 0.871, h-index: 15)
Adhesion Adhesives & Sealants     Hybrid Journal   (Followers: 7)
Administration and Policy in Mental Health and Mental Health Services Research     Partially Free   (Followers: 14, SJR: 0.795, h-index: 40)
Adsorption     Hybrid Journal   (Followers: 4, SJR: 0.774, h-index: 52)
Advances in Applied Clifford Algebras     Hybrid Journal   (Followers: 3, SJR: 0.319, h-index: 15)
Advances in Atmospheric Sciences     Hybrid Journal   (Followers: 34, SJR: 0.959, h-index: 44)
Advances in Computational Mathematics     Hybrid Journal   (Followers: 15, SJR: 1.255, h-index: 44)
Advances in Contraception     Hybrid Journal   (Followers: 2)
Advances in Data Analysis and Classification     Hybrid Journal   (Followers: 52, SJR: 1.113, h-index: 14)
Advances in Gerontology     Partially Free   (Followers: 8, SJR: 0.141, h-index: 3)
Advances in Health Sciences Education     Hybrid Journal   (Followers: 23, SJR: 1.397, h-index: 42)
Advances in Manufacturing     Hybrid Journal   (Followers: 3, SJR: 0.2, h-index: 4)
Advances in Polymer Science     Hybrid Journal   (Followers: 40, SJR: 0.637, h-index: 89)
Advances in Therapy     Hybrid Journal   (Followers: 5, SJR: 0.79, h-index: 44)
Aegean Review of the Law of the Sea and Maritime Law     Hybrid Journal   (Followers: 7)
Aequationes Mathematicae     Hybrid Journal   (Followers: 2, SJR: 0.882, h-index: 23)
Aerobiologia     Hybrid Journal   (Followers: 1, SJR: 0.511, h-index: 36)
Aesthetic Plastic Surgery     Hybrid Journal   (Followers: 8, SJR: 0.821, h-index: 49)
African Archaeological Review     Hybrid Journal   (Followers: 14, SJR: 0.612, h-index: 24)
Afrika Matematika     Hybrid Journal   (Followers: 1, SJR: 0.248, h-index: 6)
AGE     Hybrid Journal   (Followers: 7, SJR: 1.358, h-index: 33)
Ageing Intl.     Hybrid Journal   (Followers: 7, SJR: 0.337, h-index: 10)
Aggiornamenti CIO     Hybrid Journal   (Followers: 1)
Aging Clinical and Experimental Research     Hybrid Journal   (Followers: 3, SJR: 0.529, h-index: 55)
Agricultural Research     Hybrid Journal   (Followers: 3)
Agriculture and Human Values     Hybrid Journal   (Followers: 12, SJR: 1.197, h-index: 49)
Agroforestry Systems     Hybrid Journal   (Followers: 20, SJR: 0.64, h-index: 56)
Agronomy for Sustainable Development     Hybrid Journal   (Followers: 10, SJR: 1.732, h-index: 59)
AI & Society     Hybrid Journal   (Followers: 7, SJR: 0.171, h-index: 19)
AIDS and Behavior     Hybrid Journal   (Followers: 13, SJR: 2.006, h-index: 71)
Air Quality, Atmosphere & Health     Hybrid Journal   (Followers: 2, SJR: 0.706, h-index: 19)
Akupunktur & Aurikulomedizin     Full-text available via subscription   (Followers: 1)
Algebra and Logic     Hybrid Journal   (Followers: 2, SJR: 0.566, h-index: 18)
Algebra Universalis     Hybrid Journal   (Followers: 2, SJR: 0.388, h-index: 22)
Algebras and Representation Theory     Hybrid Journal   (Followers: 1, SJR: 0.868, h-index: 20)
Algorithmica     Hybrid Journal   (Followers: 7, SJR: 0.898, h-index: 56)
Allergo J.     Full-text available via subscription   (Followers: 1, SJR: 0.183, h-index: 20)
Allergo J. Intl.     Hybrid Journal   (Followers: 2)
Alpine Botany     Hybrid Journal   (Followers: 3, SJR: 0.729, h-index: 20)
ALTEX : Alternatives to Animal Experimentation     Open Access   (Followers: 3, SJR: 1.392, h-index: 32)
AMBIO     Hybrid Journal   (Followers: 14, SJR: 1.094, h-index: 87)
American J. of Cardiovascular Drugs     Hybrid Journal   (Followers: 10, SJR: 0.864, h-index: 39)
American J. of Community Psychology     Hybrid Journal   (Followers: 24, SJR: 1.237, h-index: 83)
American J. of Criminal Justice     Hybrid Journal   (Followers: 5, SJR: 0.634, h-index: 13)
American J. of Cultural Sociology     Hybrid Journal   (Followers: 11, SJR: 0.283, h-index: 3)
American J. of Dance Therapy     Hybrid Journal   (Followers: 4, SJR: 0.175, h-index: 13)
American J. of Potato Research     Hybrid Journal   (Followers: 2, SJR: 0.558, h-index: 35)
American J. of Psychoanalysis     Hybrid Journal   (Followers: 21, SJR: 0.293, h-index: 13)
American Sociologist     Hybrid Journal   (Followers: 11, SJR: 0.18, h-index: 13)
Amino Acids     Hybrid Journal   (Followers: 7, SJR: 1.362, h-index: 83)
AMS Review     Partially Free   (Followers: 4)
Analog Integrated Circuits and Signal Processing     Hybrid Journal   (Followers: 5, SJR: 0.21, h-index: 37)
Analysis and Mathematical Physics     Hybrid Journal   (Followers: 4, SJR: 0.665, h-index: 7)
Analysis in Theory and Applications     Hybrid Journal  
Analysis of Verbal Behavior     Hybrid Journal   (Followers: 4)
Analytical and Bioanalytical Chemistry     Hybrid Journal   (Followers: 28, SJR: 1.096, h-index: 123)
Anatomical Science Intl.     Hybrid Journal   (Followers: 2, SJR: 0.301, h-index: 26)
Angewandte Schmerztherapie und Palliativmedizin     Hybrid Journal  
Angiogenesis     Hybrid Journal   (Followers: 3, SJR: 2.212, h-index: 69)
Animal Cognition     Hybrid Journal   (Followers: 14, SJR: 1.122, h-index: 55)
Annales françaises de médecine d'urgence     Hybrid Journal   (Followers: 1, SJR: 0.156, h-index: 4)
Annales Henri Poincaré     Hybrid Journal   (Followers: 3, SJR: 1.377, h-index: 32)
Annales mathématiques du Québec     Hybrid Journal   (Followers: 4)
Annali dell'Universita di Ferrara     Hybrid Journal   (SJR: 0.504, h-index: 14)
Annali di Matematica Pura ed Applicata     Hybrid Journal   (Followers: 1, SJR: 1.167, h-index: 26)
Annals of Behavioral Medicine     Hybrid Journal   (Followers: 11, SJR: 2.112, h-index: 98)
Annals of Biomedical Engineering     Hybrid Journal   (Followers: 18, SJR: 1.182, h-index: 94)
Annals of Combinatorics     Hybrid Journal   (Followers: 3, SJR: 0.849, h-index: 15)
Annals of Data Science     Hybrid Journal   (Followers: 8)
Annals of Dyslexia     Hybrid Journal   (Followers: 9, SJR: 0.857, h-index: 40)
Annals of Finance     Hybrid Journal   (Followers: 27, SJR: 0.686, h-index: 14)
Annals of Forest Science     Hybrid Journal   (Followers: 4, SJR: 0.929, h-index: 57)
Annals of Global Analysis and Geometry     Hybrid Journal   (Followers: 1, SJR: 1.136, h-index: 23)
Annals of Hematology     Hybrid Journal   (Followers: 13, SJR: 1.117, h-index: 62)
Annals of Mathematics and Artificial Intelligence     Hybrid Journal   (Followers: 6, SJR: 0.593, h-index: 42)
Annals of Microbiology     Hybrid Journal   (Followers: 9, SJR: 0.402, h-index: 26)
Annals of Nuclear Medicine     Hybrid Journal   (Followers: 5, SJR: 0.68, h-index: 45)
Annals of Operations Research     Hybrid Journal   (Followers: 8, SJR: 1.186, h-index: 78)
Annals of Regional Science     Hybrid Journal   (Followers: 7, SJR: 0.405, h-index: 42)
Annals of Software Engineering     Hybrid Journal   (Followers: 12)
Annals of Solid and Structural Mechanics     Hybrid Journal   (Followers: 9, SJR: 0.553, h-index: 8)
Annals of Surgical Oncology     Hybrid Journal   (Followers: 11, SJR: 1.902, h-index: 127)
Annals of Telecommunications     Hybrid Journal   (Followers: 7, SJR: 0.315, h-index: 25)
Annals of the Institute of Statistical Mathematics     Hybrid Journal   (Followers: 1, SJR: 0.931, h-index: 31)
Antonie van Leeuwenhoek     Hybrid Journal   (Followers: 5, SJR: 0.992, h-index: 87)
Apidologie     Hybrid Journal   (Followers: 4, SJR: 1.14, h-index: 57)
APOPTOSIS     Hybrid Journal   (Followers: 7, SJR: 1.554, h-index: 87)
Applicable Algebra in Engineering, Communication and Computing     Hybrid Journal   (Followers: 2, SJR: 0.354, h-index: 27)
Applications of Mathematics     Hybrid Journal   (Followers: 1, SJR: 0.274, h-index: 20)
Applied Biochemistry and Biotechnology     Hybrid Journal   (Followers: 44, SJR: 0.575, h-index: 80)
Applied Biochemistry and Microbiology     Hybrid Journal   (Followers: 17, SJR: 0.267, h-index: 26)
Applied Categorical Structures     Hybrid Journal   (Followers: 2, SJR: 0.361, h-index: 21)
Applied Composite Materials     Hybrid Journal   (Followers: 45, SJR: 0.705, h-index: 35)
Applied Entomology and Zoology     Partially Free   (Followers: 2, SJR: 0.554, h-index: 34)
Applied Geomatics     Hybrid Journal   (Followers: 3, SJR: 0.323, h-index: 9)
Applied Geophysics     Hybrid Journal   (Followers: 7, SJR: 0.541, h-index: 13)
Applied Intelligence     Hybrid Journal   (Followers: 14, SJR: 0.777, h-index: 43)
Applied Magnetic Resonance     Hybrid Journal   (Followers: 3, SJR: 0.358, h-index: 34)
Applied Mathematics & Optimization     Hybrid Journal   (Followers: 4, SJR: 0.955, h-index: 33)
Applied Mathematics - A J. of Chinese Universities     Hybrid Journal   (SJR: 0.275, h-index: 8)
Applied Mathematics and Mechanics     Hybrid Journal   (Followers: 4, SJR: 0.37, h-index: 26)
Applied Microbiology and Biotechnology     Hybrid Journal   (Followers: 61, SJR: 1.262, h-index: 161)
Applied Physics A     Hybrid Journal   (Followers: 7, SJR: 0.535, h-index: 121)
Applied Physics B: Lasers and Optics     Hybrid Journal   (Followers: 23, SJR: 0.983, h-index: 104)
Applied Psychophysiology and Biofeedback     Hybrid Journal   (Followers: 6, SJR: 0.677, h-index: 47)
Applied Research in Quality of Life     Hybrid Journal   (Followers: 10, SJR: 0.288, h-index: 15)
Applied Solar Energy     Hybrid Journal   (Followers: 15, SJR: 0.251, h-index: 6)
Applied Spatial Analysis and Policy     Hybrid Journal   (Followers: 4, SJR: 0.351, h-index: 9)
Aquaculture Intl.     Hybrid Journal   (Followers: 21, SJR: 0.613, h-index: 40)
Aquarium Sciences and Conservation     Hybrid Journal   (Followers: 1)
Aquatic Ecology     Hybrid Journal   (Followers: 30, SJR: 0.646, h-index: 44)
Aquatic Geochemistry     Hybrid Journal   (Followers: 3, SJR: 0.764, h-index: 39)
Aquatic Sciences     Hybrid Journal   (Followers: 12, SJR: 1.172, h-index: 53)
Arabian J. for Science and Engineering     Hybrid Journal   (Followers: 5, SJR: 0.345, h-index: 20)
Arabian J. of Geosciences     Hybrid Journal   (Followers: 1, SJR: 0.417, h-index: 16)
Archaeological and Anthropological Sciences     Hybrid Journal   (Followers: 21, SJR: 1.056, h-index: 15)
Archaeologies     Hybrid Journal   (Followers: 12, SJR: 0.397, h-index: 13)
Archiv der Mathematik     Hybrid Journal   (Followers: 1, SJR: 0.597, h-index: 29)
Archival Science     Hybrid Journal   (Followers: 51, SJR: 0.804, h-index: 22)
Archive for History of Exact Sciences     Hybrid Journal   (Followers: 7, SJR: 0.28, h-index: 15)
Archive for Mathematical Logic     Hybrid Journal   (Followers: 1, SJR: 0.946, h-index: 23)
Archive for Rational Mechanics and Analysis     Hybrid Journal   (SJR: 4.091, h-index: 66)
Archive of Applied Mechanics     Hybrid Journal   (Followers: 4, SJR: 0.865, h-index: 40)
Archives of Computational Methods in Engineering     Hybrid Journal   (Followers: 4, SJR: 2.841, h-index: 40)
Archives of Dermatological Research     Hybrid Journal   (Followers: 6, SJR: 0.9, h-index: 65)
Archives of Environmental Contamination and Toxicology     Hybrid Journal   (Followers: 10, SJR: 0.846, h-index: 84)
Archives of Gynecology and Obstetrics     Hybrid Journal   (Followers: 16, SJR: 0.695, h-index: 47)
Archives of Microbiology     Hybrid Journal   (Followers: 8, SJR: 0.702, h-index: 85)
Archives of Orthopaedic and Trauma Surgery     Hybrid Journal   (Followers: 8, SJR: 1.039, h-index: 56)
Archives of Osteoporosis     Hybrid Journal   (Followers: 2, SJR: 1.092, h-index: 13)
Archives of Sexual Behavior     Hybrid Journal   (Followers: 9, SJR: 1.198, h-index: 74)
Archives of Toxicology     Hybrid Journal   (Followers: 15, SJR: 1.595, h-index: 76)
Archives of Virology     Hybrid Journal   (Followers: 5, SJR: 1.086, h-index: 90)
Archives of Women's Mental Health     Hybrid Journal   (Followers: 13, SJR: 1.264, h-index: 50)
Archivio di Ortopedia e Reumatologia     Hybrid Journal  
Archivum Immunologiae et Therapiae Experimentalis     Hybrid Journal   (Followers: 2, SJR: 1.2, h-index: 42)
ArgoSpine News & J.     Hybrid Journal   (SJR: 0.102, h-index: 3)
Argumentation     Hybrid Journal   (Followers: 4, SJR: 0.295, h-index: 18)
Arid Ecosystems     Hybrid Journal   (Followers: 3)
Arkiv för Matematik     Hybrid Journal   (Followers: 1, SJR: 0.948, h-index: 22)
Arnold Mathematical J.     Hybrid Journal   (Followers: 1)
Arthropod-Plant Interactions     Hybrid Journal   (Followers: 2, SJR: 0.797, h-index: 17)
Arthroskopie     Hybrid Journal   (Followers: 1, SJR: 0.145, h-index: 8)
Artificial Intelligence and Law     Hybrid Journal   (Followers: 10, SJR: 0.288, h-index: 25)
Artificial Intelligence Review     Hybrid Journal   (Followers: 15, SJR: 0.948, h-index: 48)
Artificial Life and Robotics     Hybrid Journal   (Followers: 8, SJR: 0.231, h-index: 14)
Asia Europe J.     Hybrid Journal   (Followers: 4, SJR: 0.247, h-index: 9)
Asia Pacific Education Review     Hybrid Journal   (Followers: 9, SJR: 0.371, h-index: 17)
Asia Pacific J. of Management     Hybrid Journal   (Followers: 11, SJR: 1.676, h-index: 50)
Asia-Pacific Education Researcher     Hybrid Journal   (Followers: 11, SJR: 0.353, h-index: 13)
Asia-Pacific Financial Markets     Hybrid Journal   (Followers: 2, SJR: 0.19, h-index: 15)
Asia-Pacific J. of Atmospheric Sciences     Hybrid Journal   (Followers: 20, SJR: 1.006, h-index: 14)
Asian Business & Management     Hybrid Journal   (Followers: 7, SJR: 0.41, h-index: 10)
Asian J. of Business Ethics     Hybrid Journal   (Followers: 7)
Asian J. of Criminology     Hybrid Journal   (Followers: 5, SJR: 0.263, h-index: 8)
AStA Advances in Statistical Analysis     Hybrid Journal   (Followers: 2, SJR: 0.681, h-index: 15)
AStA Wirtschafts- und Sozialstatistisches Archiv     Hybrid Journal   (Followers: 5, SJR: 0.195, h-index: 5)
ästhetische dermatologie & kosmetologie     Full-text available via subscription  
Astronomy and Astrophysics Review     Hybrid Journal   (Followers: 21, SJR: 4.511, h-index: 44)
Astronomy Letters     Hybrid Journal   (Followers: 19, SJR: 0.58, h-index: 30)
Astronomy Reports     Hybrid Journal   (Followers: 12, SJR: 0.473, h-index: 23)
Astrophysical Bulletin     Hybrid Journal   (Followers: 2, SJR: 0.469, h-index: 11)

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Journal Cover Aging Clinical and Experimental Research
  [SJR: 0.529]   [H-I: 55]   [3 followers]  Follow
    
   Hybrid Journal Hybrid journal (It can contain Open Access articles)
   ISSN (Print) 1720-8319 - ISSN (Online) 1720-8319
   Published by Springer-Verlag Homepage  [2341 journals]
  • Relationship between the polymorphism in exon 5 of BACE1 gene and
           Alzheimer’s disease
    • Authors: Mingjie Wang; Jinsong Yang; Jianhua Su
      Pages: 105 - 113
      Abstract: Background and aims The β-Site APP-cleaving enzyme 1 (BACE1) gene polymorphism (rs638405) has been extensively investigated for association to Alzheimer’s disease (AD). However, results of different studies have been contradictory. The aim of this meta-analysis was to evaluate the association between BACE1 gene polymorphism (rs638405) and AD. Methods All eligible studies were searched in PubMed, Cochrane Library, Embase, SinoMed, and the China Knowledge Resource Integrated Database. Pooled odds ratios (ORs) and 95 % confidence intervals (95 % CIs) were used to evaluate the strength of the association between BACE1 gene polymorphism and AD. Results Twenty studies in 19 papers containing 4377 AD patients and 4563 controls were included for rs638405 polymorphism. The results suggested that rs638405 in BACE1 was not associated with the risk of AD. Stratification analyses indicated rs638405 decreased the risk of apolipoprotein-E ε4 (APOE4) positive AD patients. Furthermore, we found rs638405 also decreased the risk of Asian AD patients. By exclusion of three studies that did not conform to Hardy–Weinberg equilibrium (HWE), our data suggested rs638405 in BACE1 was a protective factor of AD. Conclusions To sum up, our data indicated that BACE1 gene polymorphism in exon 5 might decrease the risk of Asian AD and APOE4 positive patients.
      PubDate: 2017-04-01
      DOI: 10.1007/s40520-016-0539-0
      Issue No: Vol. 29, No. 2 (2017)
       
  • Vitamin B12 screening in metformin-treated diabetics in primary care: were
           elderly patients less likely to be tested?
    • Authors: Yacov Fogelman; Eliezer Kitai; Gari Blumberg; Avivit Golan-Cohen; Micha Rapoport; Eli Carmeli
      Pages: 135 - 139
      Abstract: Abstract Low serum B12 level is a common occurrence in patients with type 2 diabetes (T2DM) treated with metformin. There is lack of evidence concerning blood testing of vitamin B12 and current clinical guidelines make no recommendations on the detection or prevention of vitamin B-12 deficiency during metformin treatment. Our objective was to examine the current practice and clinical determinants of vitamin B12 testing in metformin treated T2DM patients. Data were collected from health maintenance organization patients, and consisted of T2DM patients who were newly prescribed metformin from 2008 to 2013. Patients were randomly divided into two subgroups: referred for a vitamin B12 blood test, and did not receive a referral. The demographic data and medical characteristics were analyzed. 5131 patients began taking metformin during the study period. Of these 2332 (44.5 %) had vitamin B12 tested. Significant differences were found between the groups in regard to glycosylated hemoglobin, low density lipoprotein, systolic blood pressure, dyslipidemia, chronic renal failure, and disease duration. A significant positive association (p < .05) was found between vitamin B12 testing and insulin treatment, retinopathy, neuropathy and hypertension. Vitamin B12 in elderly (>75 years) patients was significantly lower (p < .01). Insulin treatment, hypertension, and chronic diabetic complications in metformin treated T2DM patients are associated with higher rates of vitamin B12 testing. T2DM patients 75 years and above were less likely to be tested for B12 deficiency.
      PubDate: 2017-04-01
      DOI: 10.1007/s40520-016-0546-1
      Issue No: Vol. 29, No. 2 (2017)
       
  • Chronic idiopathic normocytic anaemia in older people: the risk factors
           and the role of age-associated renal impairment
    • Authors: Mahesan Anpalahan; Steven Savvas; Kar Yan Lo; Hui Yi Ng; Stephen Gibson
      Pages: 147 - 155
      Abstract: Objectives To characterise the risk factors for chronic idiopathic normocytic anaemia (CINA) in older people, particularly the role of age-associated renal impairment. Methods Patients aged ≥65 years admitted to a medical unit over 12 months were assessed. Those with secondary causes of anaemia including chronic kidney disease (CKD) were excluded. CINA was defined as a haemoglobin <130 g/l for men and <120 g/l for women for at least 6 months without any apparent cause. Renal function was determined by estimating creatinine clearance (CrCl) using Cockcroft–Gault formula, and glomerular filtration rate (GFR) using modification of diet in renal disease (MDRD) and chronic kidney disease epidemiology collaboration (CKD-EPI) formulas. Results 116 had CINA. Controls were 572. The mean estimates of renal function were significantly lower in cases as compared with controls (P < 0.001). The risk of CINA increased by 12.6, 10.4 and 12 %, respectively, for each unit decrease in CrCl, MDRD-eGFR and CKD-EPI-eGFR, independent of age and other covariates. The adjusted odds ratios for CINA in those with CrCl, MDRD or CKD-EPI eGFR <60 ml/min/1.73 m2 were 2.68 (CI 1.53–4.70); 2.70 (CI 1.57–4.62) and 2.12 (CI 1.46–3.74), respectively. Other covariates in the model that were independently associated with CINA included advanced age, diabetes mellitus (DM), use of angiotensin converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB), history of dementia and living in a residential care facility. Conclusions Age-associated renal impairment independently contributes to CINA. Other potential risk factors for CINA include advanced age, DM and ACEI or ARB use.
      PubDate: 2017-04-01
      DOI: 10.1007/s40520-016-0563-0
      Issue No: Vol. 29, No. 2 (2017)
       
  • Relationship between FEV 1 and arterial stiffness in elderly people with
           chronic obstructive pulmonary disease
    • Authors: Luisa Costanzo; Claudio Pedone; Fabrizio Battistoni; Domenica Chiurco; Simona Santangelo; Raffaele Antonelli-Incalzi
      Pages: 157 - 164
      Abstract: Background Chronic obstructive pulmonary disease (COPD) is highly prevalent in the elderly, and both COPD and age per se are associated with cardiovascular morbidity. Aims We tested the hypothesis that in elderly COPD patients airflow limitation is associated with arterial stiffness and the relationship, if any, is related to endothelial function and systemic inflammation. Methods We evaluated lung function, augmentation index (AIx), flow-mediated dilation (FMD), Interleukin-6 (IL-6), and asymmetric dymethilarginine (ADMA) levels in 76 subjects (mean age 73.9 years, SD 6.2) attending a geriatric outpatient clinic. Results Participants with COPD (N = 41) and controls (N = 35) did not differ in terms of AIx (30 vs 28.2 %, P = 0.30) and FMD (14.2 vs 12.3 %, P = 0.10). Similarly, the two groups did not differ with respect to mean concentrations of inflammation markers (IL-6 and C-reactive protein) and ADMA. Among COPD participants there was an inverse correlation between AIx and Forced Expiratory Volume in the first second (r = −0.349, P = 0.02). This relationship remained significant after correction for potential confounders, including markers of inflammation and ADMA levels (β = −0.194, P = 0.001). Discussion According to the results of this study, among COPD patients, bronchial patency and AIx are inversely related, and the relationship is explained neither by endothelial function nor by systemic inflammation. Conclusions In elderly COPD people, increased arterial stiffness is related to reduced pulmonary function and it seems worth testing as a potential marker of higher cardiovascular risk.
      PubDate: 2017-04-01
      DOI: 10.1007/s40520-016-0560-3
      Issue No: Vol. 29, No. 2 (2017)
       
  • Risk factors for cognitive decline associated with gait speed in
           community-dwelling elderly Koreans with MMSE scores of 30
    • Authors: Kye-Yeung Park; Hwan-Sik Hwang; Yeon-Pyo Kim; Hoon-Ki Park
      Pages: 183 - 189
      Abstract: Background and aim We aimed to investigate the association between lower gait speed and cognitive decline over a 3-year period in community-dwelling older people with mini–mental state examination (MMSE) scores of 30 at baseline. Methods The study was based on data from 10,003 Koreans aged 60 years or older who completed the National Elderly Survey in both 2008 and 2011. Among them 620 subjects achieved MMSE scores of 30 in 2008. Over a 3-year period, preservation of MMSE score 28 or more was defined as preserved cognition and decrease of three or more points as cognitive decline. A 4-m gait speed was measured at baseline. Data on sociodemographic factors (age, number of schooling years, and household composition), alcohol drinking, current smokers, Korean version of Short form Geriatric Depression Scale score, and self-reported comorbid conditions, were collected. Results Of 620 (weighted 884) respondents included in the analysis, 208 (52.3 %) of 398 males (weighted 567) and 152 (68.5 %) of 222 females (weighted 317) suffered cognitive decline over the 3-year period. After adjustment, lower gait speed was associated with cognitive decline in males (OR 2.29; 95 % CI 1.07–4.89, P = 0.032). Educational level was a significant risk factor for both men and women (OR 0.86; 95 % CI 0.79–0.93 in males, OR 0.75; 95 % CI 0.65–0.87 in females). Males diagnosed with hypertension (OR 0.44; 95 % CI 0.22–0.88) or male smokers (OR 0.38; 95 % CI 0.19–0.75) were significantly less likely to have cognitive decline. There was no significant association between cognitive decline and gait speed in females. Conclusions Higher 4-m gait speed is associated with preservation of cognitive function over time in men, but not in women.
      PubDate: 2017-04-01
      DOI: 10.1007/s40520-016-0565-y
      Issue No: Vol. 29, No. 2 (2017)
       
  • Learning to recognize younger faces at an older age
    • Authors: Sven Obermeyer; Veit Kubik; Andreas Schaich; Thorsten Kolling; Monika Knopf
      Pages: 191 - 196
      Abstract: Objectives Processing of horizontal face cues has been shown to be an important element in face recognition of adults aged up to 30 years. In contrast, horizontally aligned facial features do not appear to contribute to older adults’ (60–75 years) recognition in a similar way. To this end, we investigated potential learning effects on the ability to recognize faces based on horizontal features. Previous research suggests face recognition based on all face information experiences an accelerated decline after the age of 70. However, recognition based only on horizontal face information has not yet been studied in old age (75+ years of age). Thus, we investigated whether older adults (aged up to as well as starting at 75 years) can learn to recognize faces based on horizontal face cues alone. Method One younger and two older adult groups (20–30, 60–75, and 75+ years) were familiarized with a high and a low amount of previously unfamiliar faces—some containing all face cues and others containing only horizontal face cues (reduced information). Subsequently, all groups received a recognition test. Results Repeated learning increased natural face recognition for all three age groups when all face cues were available. However, increases in face recognition were only observed for younger adults when horizontal face cued were only available. Discussion The importance of horizontally aligned spatial frequencies for recognizing human faces is lessened before the age of 60 (and plateaus thereon), whereas recognition of stimuli containing all face cues is still capable of improvement.
      PubDate: 2017-04-01
      DOI: 10.1007/s40520-016-0537-2
      Issue No: Vol. 29, No. 2 (2017)
       
  • Age-related differences in Fukuda stepping and Babinski-Weil tests,
           within-day variability and test–retest reliability
    • Authors: Nicole Paquet; Deborah A. Jehu; Yves Lajoie
      Pages: 223 - 230
      Abstract: Background The Fukuda stepping and Babinski-Weil tests are associated with unperceived body rotation and linear displacements in young adults, but performance in older adults on these two tests has yet to be determined. Aim The main purpose was to compare the performance and reliability of the Fukuda stepping and Babinski-Weil tests in young and older adults. Methods Fifty older and 50 young adults executed three trials of each test on day 1 (test) and day 2 (retest). Lateral and longitudinal displacements and body rotation relative to the starting position were measured. Means and standard deviations (SD) were compared between the two groups with Mann–Whitney tests. Test–retest reliability was assessed with intra-class correlation coefficients (ICC). Foot preference was determined from the score on the Waterloo Footedness Questionnaire and correlated with test scores. Results Lateral and longitudinal displacements were significantly larger in older than young participants on the Fukuda stepping test (p < .01) and significantly smaller on the Babinski-Weil test (p < .001). Older participants displayed a significantly smaller SD on the three Babinski-Weil test trials (p < .001). Displacement and rotation measures ICC ranged between 0.25 and 0.77 in older and between 0.58 and 0.80 in young participants. Foot preference correlated with rotation on the Fukuda stepping test in young (p < .05), but not in older participants (p > .05). Discussion and conclusion Linear displacements, but not body rotation, were different between older and young adults. There was no clear age-related differences in test–retest reliability, but the moderate reliability indicates that performance can vary from day to day in both age groups.
      PubDate: 2017-04-01
      DOI: 10.1007/s40520-016-0544-3
      Issue No: Vol. 29, No. 2 (2017)
       
  • Physical activity, diet quality, and mortality among sarcopenic older
           adults
    • Authors: Justin C. Brown; Michael O. Harhay; Meera N. Harhay
      Pages: 257 - 263
      Abstract: Background It is unknown if physical activity and good diet quality modify the risk of poor outcomes, such as mortality, among older adults with sarcopenia. Aim To examine if physical activity and good diet quality modify the risk of poor outcomes, such as mortality, among older adults with sarcopenia. Methods A population-based cohort study among 1618 older adults with sarcopenia from the Third National Health and Nutrition Survey (NHANES III; 1988–1994). Sarcopenia was defined by the European Working Group on Sarcopenia in Older People. Physical activity was self-reported, and classified as sedentary (0 bouts per week), physically inactive (1–4 bouts per week), and physically active (≥5 bouts per week). Diet quality was assessed with the healthy eating index (a scale of 0–100 representing adherence to federal dietary recommendations), and classified as poor (<51), fair (51–80), and good (>80) diet quality. Results Compared to participants who were sedentary, those who were physically inactive were 16 % less likely to die [HR 0.84 (95 % CI 0.64–1.09)], and those who were physically active were 25 % less likely to die [HR 0.75 (95 % CI 0.59–0.97); P trend = 0.026]. Compared to participants with poor diet quality, those with fair diet quality were 37 % less likely to die [HR 0.63 (95 % CI 0.47–0.86)], and those with good diet quality were 45 % less likely to die [HR 0.55 (95 % CI 0.37–0.80); P trend = 0.002]. Conclusions Participation in physical activity and consumption of a healthy diet correspond with a lower risk of mortality among older adults with sarcopenia. Randomized trials are needed in this population.
      PubDate: 2017-04-01
      DOI: 10.1007/s40520-016-0559-9
      Issue No: Vol. 29, No. 2 (2017)
       
  • Comparison of the measurement properties of the Functional Independence
           and Difficulty Scale with the Barthel Index in community-dwelling elderly
           people in Japan
    • Authors: Takashi Saito; Kazuhiro P. Izawa; Nobuko Matsui; Kenji Arai; Makoto Ando; Kazuhiro Morimoto; Naoki Fujita; Yuki Takahashi; Moe Kawazoe; Shuichiro Watanabe
      Pages: 273 - 281
      Abstract: Background The new Functional Independence and Difficulty Scale (FIDS) is a tool for assessing the performance of basic activities of daily living (BADL). Because many BADL measures already exist, it is important to know whether FIDS can offer added benefit over the existing measures. Aims This study compared measurement properties between the FIDS and a representative BADL assessment tool, the Barthel Index (BI). Methods Recruitment of the participants was done on the basis of convenience sampling. Participants were community-dwelling elderly Japanese subjects (n = 314; age ≥65 years) divided into a healthy elderly group [n = 225; subjects not using long-term care insurance (LTCI) services] and frail elderly group (n = 89; subjects using LTCI services). For each group, ceiling effect (percent participation with the maximum score) was calculated, and it was compared between the two scales. Associations between the FIDS, BI and Medical Outcomes Study Short Form 8 Health Survey (SF-8) were evaluated by Spearman correlation coefficient and partial correlations. Partial correlations coefficients to SF-8 were compared between the two scales. Results FIDS showed a relatively small ceiling effect compared to the BI. Compared to the BI, FIDS showed a significant positive partial correlation with the broader aspect of the SF-8 subscales, but the strength of correlation between FIDS and SF-8 was weak to negligible. Conclusions The FIDS might be less affected by ceiling effect than the BI. Additional studies using a sufficient number of probability samples are needed to clarify whether FIDS has any benefit over BI in terms of correlations with the SF-8.
      PubDate: 2017-04-01
      DOI: 10.1007/s40520-016-0558-x
      Issue No: Vol. 29, No. 2 (2017)
       
  • Apical aneurysm with thrombus in an elderly patient with hypertrophic
           obstructive cardiomyopathy
    • Authors: Maria Bonou; Eva D. Papadimitraki; Nikolaos Dalianis; Nikolaos Alexopoulos; Maria Karali; Kanella Zerva; John Barbetseas
      Pages: 341 - 344
      PubDate: 2017-04-01
      DOI: 10.1007/s40520-016-0551-4
      Issue No: Vol. 29, No. 2 (2017)
       
  • Combined use of the multidimensional prognostic index (MPI) and
           procalcitonin serum levels in predicting 1-month mortality risk in older
           patients hospitalized with community-acquired pneumonia (CAP): a
           prospective study
    • Authors: Alberto Pilotto; Simone Dini; Julia Daragjati; Manuela Miolo; Monica Maria Mion; Andrea Fontana; Mario Lo Storto; Martina Zaninotto; Alberto Cella; Paolo Carraro; Filomena Addante; Massimiliano Copetti; Mario Plebani
      Abstract: Background Several scores and biomarkers, i.e., procalcitonin (PCT), were proposed to stratify the mortality risk in community-acquired pneumonia (CAP). Aim Evaluating prognostic accuracy of PCT and Multidimensional Prognostic Index (MPI) for 1-month mortality risk in older patients with CAP. Methods At hospital admission and at discharge, patients were evaluated by a Comprehensive Geriatric Assessment to calculate MPI. Serum PCT was measured at admission and 1, 3, and 5 days after hospital admission. Results 49 patients were enrolled. The overall 1-month mortality was 44.5 for 100-persons year. Mortality rates were higher with the increasing of MPI. In survived patients, MPI at discharge showed higher predictive accuracy than MPI at admission. Adding PCT levels to admission MPI prognostic accuracy for 1-month mortality significantly increased. Conclusion In older patients with CAP, MPI significantly predicted 1 month mortality. PCT levels significantly improved the accuracy of MPI at admission in predicting 1-month mortality.
      PubDate: 2017-04-17
      DOI: 10.1007/s40520-017-0759-y
       
  • Criterion-related validity of self-reported stair climbing in older adults
    • Authors: Sara Higueras-Fresnillo; Irene Esteban-Cornejo; Pablo Gasque; Oscar L. Veiga; David Martinez-Gomez
      Abstract: Introduction Stair climbing is an activity of daily living that might contribute to increase levels of physical activity (PA). To date, there is no study examining the validity of climbing stairs assessed by self-report. The aim of this study was, therefore, to examine the validity of estimated stair climbing from one question included in a common questionnaire compared to a pattern-recognition activity monitor in older adults. Methods A total of 138 older adults (94 women), aged 65–86 years (70.9 ± 4.7 years), from the IMPACT65 + study participated in this validity study. Estimates of stair climbing were obtained from the European Prospective Investigation into Cancer and Nutrition (EPIC) PA questionnaire. An objective assessment of stair climbing was obtained with the Intelligent Device for Energy Expenditure and Activity (IDEEA) monitor. Results The correlation between both methods to assess stair climbing was fair (ρ = 0.22, p = 0.008 for PA energy expenditure and ρ = 0.26, p = 0.002 for duration). Mean differences between self-report and the IDEEA were 7.96 ± 10.52 vs. 9.88 ± 3.32 METs-min/day for PA energy expenditure, and 0.99 ± 1.32 vs. 1.79 ± 2.02 min/day for duration (both Wilcoxon test p < 0.001). Results from the Bland–Altman analysis indicate that bias between both instruments were −1.91 ± 10.30 METs-min/day and −0.80 ± 1.99 min/day, and corresponding limits of agreement for the two instruments were from 18.27 to −22.10 METs-min/day and from 3.09 to −4.70 min/day, respectively. Conclusion Our results indicate that self-reported stair climbing has modest validity to accurately rank old age participants, and underestimates both PAEE and its duration, as compared with an objectively measured method.
      PubDate: 2017-04-17
      DOI: 10.1007/s40520-017-0761-4
       
  • The impact of polypharmacy and drug interactions among the elderly
           population in Western Sicily, Italy
    • Authors: Giulia Scondotto; Fanny Pojero; Sebastiano Pollina Addario; Mauro Ferrante; Maurizio Pastorello; Michele Visconti; Salvatore Scondotto; Alessandra Casuccio
      Abstract: Aim Primary endpoint was to report polypharmacy distribution in the general population vs ≥65 years old people and to examine the frequency of drug–drug interactions (DDIs) in the Health Local Unit of Palermo, Italy, in relationship with patients’ age. Methods Drug prescription data for the year 2014 were extracted from the database of the Local Health Unit of Palermo Province, Italy. Patients were divided into five age groups (0–13, 14–64, 65–69, 70–74, and ≥75 year old). The detection of potential DDIs in polypharmacy profiles was performed with NavFarma software (Infologic srl, Padova, Italia), with DDI classification provided by tool Micromedex Drug Reax (Truven Health Analitics, Michigan, USA). Results We analyzed data of 1,324,641 patients, and 15,801,191 medical prescription were recorded; of these, 11,337,796 regarded chronic conditions. The drug prescriptions reached the highest values in the 65–69 and 70–74 age groups (p = 0.005 and p = 0.008 vs age 14–64 respectively). An overall amount of 6,094,373 DDIs were detected, of which 47,173 were contraindicated. Median number of DDIs was higher in 65–69 and 70–74 age groups (p = 0.008 and p = 0.012 vs age 14–64, respectively). Regarding contraindicated DDIs a significant difference was detected comparing 14–64 vs ≥65 age groups (p = 0.010 vs 65–69 group, p = 0.005 vs 70–74 group and ≥75 group). Conclusions Polypharmacy is a phenomenon acquiring increasing dimensions also in our province. It interests particularly the older subjects, and assumes a dramatic accent when it is put in relationship with the frequency of DDIs. A proactive vigilance about potential life threatening drug interactions is mandatory.
      PubDate: 2017-04-12
      DOI: 10.1007/s40520-017-0755-2
       
  • The effects of age and sex on hand movement structure
    • Authors: A. Sebastjan; A. Skrzek; Z. Ignasiak; T. Sławińska
      Abstract: Abstract The aim was to investigate the effects of age and sex on hand function and ascertain age-related changes (magnitude and rate) by assessing a broad range of functional tasks with the dominant and non-dominant hands. A representative sample of 635 adults (114 males and 491 females) aged 50 years and over completed motor performance series of the Vienna Test System Parametric and non-parametric analysis and simple linear regression was used to examine the relationships. Significant relationships were observed between task performance and age and sex, although the contributions of both factors differed by varying degree. Compared with males, the females performed significantly better than males in the majority of tests, particularly with the dominant hand, although greater age-related reductions were observed in performance. Among the skills quantifying hand function, age accounted for the most variance in hand and finger dexterity.
      PubDate: 2017-04-11
      DOI: 10.1007/s40520-017-0758-z
       
  • Swallowing impairment is a significant factor for predicting life
           prognosis of elderly at the end of life
    • Authors: Koji Naruishi; Yasufumi Nishikawa
      Abstract: Background In end-of-life care of elderly, the decision of care plan including gastrostomy is difficult frequently because of insufficient knowledge relating the life prognosis of elderly. It is important the families to decide correctly the life prognosis of elderly with geriatric diseases. Our purpose is to examine the significant factors for predicting life prognosis of elderly in end-of-life care. Methods A total of 320 elderly patients was enrolled (male/female 151/169; averaged age: male 84.7 ± 5.9 year, female 86.8 ± 6.3 year) and retrospective analyses were performed. The elderly patients were classified as either: (1) with or without past illness of aspiration pneumonia; (2) with or without incidence of cerebrovascular disorder; (3) impaired or normal cognitive function; (4) impaired or normal swallowing function, and performed Kaplan–Meier survival analysis. Swallowing function was examined using video endoscopic (VE) evaluation method. The Kaplan–Meier analysis of the number of days from implementation of VE test (day 0) to death was evaluated with the log-rank Mantel–Cox test. The maximum follow-up time recorded was 180 days. Results There were no significant differences in number of days when divided with or without past illness of aspiration pneumonia, cerebrovascular disorder and impaired cognitive function. The survival probabilities of elderly with impaired swallowing function were significant lower than in elderly with the normal function. Conclusions For judgement of life prognosis, the condition of being frail such as impaired swallowing function might be a useful factor, and the viewpoint would contribute to decide the treatment plan for the good end-of-life care of elderly.
      PubDate: 2017-04-08
      DOI: 10.1007/s40520-017-0756-1
       
  • Ageism and surgical treatment of breast cancer in Italian hospitals
    • Authors: Mirko Di Rosa; Carlos Chiatti; Joseph M. Rimland; Marina Capasso; Valerio M. Scandali; Emilia Prospero; Andrea Corsonello; Fabrizia Lattanzio
      Abstract: Aim To determine if age is a factor influencing the type of breast cancer surgery (radical versus conservative) in Italy and to investigate the regional differences in breast cancer surgery clinical practice. Methods Retrospective study is based on national hospital discharge records. The study draws on routinely collected data from hospital discharge records in Italy in 2010. The following exclusion criteria were applied: day hospital stays, patients younger than 17 years, males, patients without an ICD-9CM code indicating breast cancer and breast surgery, and repeated hospital admission of the same patient. Overall, 49,058 patient records were selected for the analysis. Results The proportion of conservative breast cancer operations was 70.9%. A greater number of women younger than 70 had undergone a breast-conserving operation compared to older women. There were regional variations ranging from a minimum in Basilicata to a maximum in Val d’Aosta. Multivariate analysis revealed that older patients with lower clinical severity were more likely to have undergone a radical operation than younger women. In addition, radical surgery was approximately twice as likely to occur in a private hospital that performed at least 50 breast cancer operations annually than in a public hospital that performed <50 breast surgeries. Conclusion Notwithstanding increases in life expectancy and the lack of clinical evidence to support the use of age as a surrogate for co-morbid conditions and frailty, our data on breast cancer operations in Italy are consistent with the hypothesis suggesting the persistence of ageistic practice in the healthcare system.
      PubDate: 2017-04-08
      DOI: 10.1007/s40520-017-0757-0
       
  • Association between education level and potentially inappropriate
           medication among older patients
    • Authors: Chia-Ter Chao; On behalf of the COGENT study group; Hung-Bin Tsai; Chih-Kang Chiang; Jenq-Wen Huang; Kuan-Yu Hung
      PubDate: 2017-04-06
      DOI: 10.1007/s40520-017-0743-6
       
  • Fall-induced wounds and lacerations in older Finns between 1970 and 2014
    • Authors: Pekka Kannus; Seppo Niemi; Harri Sievänen; Jari Parkkari
      Abstract: Background Fall-induced injuries in elderly people are a growing public health issue. Aim We aimed to determine the current trends in the fall-induced severe wounds and lacerations among older adults in Finland—an EU country with a well-defined Caucasian population of 5.5 million. Methods The injury trends were assessed by taking into account all persons 80 years of age or older who were admitted to Finnish hospitals for primary treatment of these injuries during 1970–2014. Results The number of fall-induced severe wounds and lacerations among 80-year-old or older Finnish adults showed a sharp increase during the 44-year follow-up, from 52 in 1970 to 1393 in 2014. The age-adjusted incidence of injury (per 100,000 persons) also showed a clear rise from 1970 to 2014: from 98.3 to 511.5 in women, and from 92.0 to 395.3 in men. In both sexes, the increase was greatest in the oldest age group (persons 90 years of age or older). Conclusions The number of fall-induced severe wounds and lacerations among older Finnish persons rose in 1970–2014 with a rate that could not be explained merely by demographic changes. Further studies should focus on detailed understanding of the reasons for the rise and assessing possibilities for fall and injury prevention.
      PubDate: 2017-04-05
      DOI: 10.1007/s40520-017-0753-4
       
  • Can older adults improve the identification of moderate intensity using
           walking cadence'
    • Authors: A. G. McLellan; Jana Slaght; C. M. Craig; A. Mayo; M. Sénéchal; Danielle R. Bouchard
      Abstract: Background The majority of older adults do not reach the physical activity guidelines. One possible explanation for this may be that older adults overestimate their physical activity levels, because they are unable to identify exercise intensity. Methods Forty-four older adults were recruited and randomly assigned into two walking groups lasting 6 weeks. The intervention group was asked to walk a minimum of 150 min per week at moderate intensity using walking cadence indicated with a pedometer. The control group did not get any feedback on walking intensity. Results The ability to identify moderate intensity while walking did not significantly improve in neither groups (p = 0.530). However, participants in the intervention group increased significantly the time spent at moderate intensity, in 10 min bouts (p < 0.01). Discussion A pedometer providing walking cadence to reach moderate intensity is a good tool for increasing time walked at the recommended intensity, but not because participants know more what is considered moderate intensity.
      PubDate: 2017-04-04
      DOI: 10.1007/s40520-017-0746-3
       
  • Tools for assessing fall risk in the elderly: a systematic review and
           meta-analysis
    • Authors: Seong-Hi Park
      Abstract: Abstract The prevention of falls among the elderly is arguably one of the most important public health issues in today’s aging society. The aim of this study was to assess which tools best predict the risk of falls in the elderly. Electronic searches were performed using Medline, EMBASE, the Cochrane Library, CINAHL, etc., using the following keywords: “fall risk assessment”, “elderly fall screening”, and “elderly mobility scale”. The QUADAS-2 was applied to assess the internal validity of the diagnostic studies. Selected studies were meta-analyzed with MetaDisc 1.4. A total of 33 studies were eligible out of the 2,321 studies retrieved from selected databases. Twenty-six assessment tools for fall risk were used in the selected articles, and they tended to vary based on the setting. The fall risk assessment tools currently used for the elderly did not show sufficiently high predictive validity for differentiating high and low fall risks. The Berg Balance scale and Mobility Interaction Fall chart showed stable and high specificity, while the Downton Fall Risk Index, Hendrich II Fall Risk Model, St. Thomas’s Risk Assessment Tool in Falling elderly inpatients, Timed Up and Go test, and Tinetti Balance scale showed the opposite results. We concluded that rather than a single measure, two assessment tools used together would better evaluate the characteristics of falls by the elderly that can occur due to a multitude of factors and maximize the advantages of each for predicting the occurrence of falls.
      PubDate: 2017-04-03
      DOI: 10.1007/s40520-017-0749-0
       
 
 
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