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Publisher: Sage Publications   (Total: 998 journals)

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Showing 1 - 200 of 998 Journals sorted alphabetically
AADE in Practice     Hybrid Journal   (Followers: 3)
Abstracts in Anthropology     Full-text available via subscription   (Followers: 10)
Academic Pathology     Open Access   (Followers: 2)
Accounting History     Hybrid Journal   (Followers: 15, SJR: 0.357, h-index: 19)
Acta Radiologica     Hybrid Journal   (Followers: 3, SJR: 0.728, h-index: 57)
Acta Radiologica Open     Open Access   (Followers: 3)
Acta Sociologica     Hybrid Journal   (Followers: 26, SJR: 0.618, h-index: 33)
Action Research     Hybrid Journal   (Followers: 39, SJR: 0.33, h-index: 15)
Active Learning in Higher Education     Hybrid Journal   (Followers: 238, SJR: 1.099, h-index: 22)
Adaptive Behavior     Hybrid Journal   (Followers: 11, SJR: 0.462, h-index: 41)
Administration & Society     Hybrid Journal   (Followers: 11, SJR: 0.88, h-index: 39)
Adoption & Fostering     Hybrid Journal   (Followers: 19)
Adsorption Science & Technology     Full-text available via subscription   (Followers: 5, SJR: 0.239, h-index: 27)
Adult Education Quarterly     Hybrid Journal   (Followers: 173, SJR: 0.515, h-index: 33)
Adult Learning     Hybrid Journal   (Followers: 26)
Advances in Dental Research     Hybrid Journal   (Followers: 2, SJR: 1.023, h-index: 47)
Advances in Developing Human Resources     Hybrid Journal   (Followers: 21, SJR: 0.293, h-index: 17)
Advances in Mechanical Engineering     Open Access   (Followers: 82, SJR: 0.255, h-index: 14)
Advances in Structural Engineering     Full-text available via subscription   (Followers: 27, SJR: 0.475, h-index: 24)
Advances in Tumor Virology     Open Access   (Followers: 2)
AERA Open     Open Access   (Followers: 6)
Affilia     Hybrid Journal   (Followers: 3, SJR: 0.441, h-index: 22)
Agrarian South : J. of Political Economy     Hybrid Journal   (Followers: 1)
Air, Soil & Water Research     Open Access   (Followers: 7, SJR: 0.173, h-index: 6)
Alexandria : The J. of National and Intl. Library and Information Issues     Full-text available via subscription   (Followers: 65)
Alternative Law J.     Hybrid Journal   (Followers: 3)
Alternatives : Global, Local, Political     Hybrid Journal   (Followers: 16, SJR: 0.46, h-index: 29)
American Behavioral Scientist     Hybrid Journal   (Followers: 16, SJR: 1.007, h-index: 72)
American Economist     Hybrid Journal   (Followers: 2)
American Educational Research J.     Hybrid Journal   (Followers: 143, SJR: 3.879, h-index: 83)
American J. of Alzheimer's Disease and Other Dementias     Hybrid Journal   (Followers: 14, SJR: 0.577, h-index: 40)
American J. of Cosmetic Surgery     Hybrid Journal   (Followers: 4)
American J. of Evaluation     Hybrid Journal   (Followers: 13, SJR: 0.5, h-index: 39)
American J. of Health Promotion     Hybrid Journal   (Followers: 23, SJR: 0.821, h-index: 72)
American J. of Hospice and Palliative Medicine     Hybrid Journal   (Followers: 31, SJR: 0.527, h-index: 35)
American J. of Law & Medicine     Full-text available via subscription   (Followers: 12, SJR: 0.279, h-index: 23)
American J. of Lifestyle Medicine     Hybrid Journal   (Followers: 5, SJR: 0.359, h-index: 8)
American J. of Medical Quality     Hybrid Journal   (Followers: 7, SJR: 0.718, h-index: 40)
American J. of Men's Health     Hybrid Journal   (Followers: 6, SJR: 0.673, h-index: 19)
American J. of Sports Medicine     Hybrid Journal   (Followers: 197, SJR: 3.333, h-index: 160)
American Politics Research     Hybrid Journal   (Followers: 25, SJR: 1.1, h-index: 36)
American Review of Public Administration     Hybrid Journal   (Followers: 16, SJR: 1.699, h-index: 33)
American Sociological Review     Hybrid Journal   (Followers: 199, SJR: 4.644, h-index: 141)
Analytical Chemistry Insights     Open Access   (Followers: 22, SJR: 0.354, h-index: 11)
Angiology     Hybrid Journal   (Followers: 2, SJR: 0.598, h-index: 53)
Animation     Hybrid Journal   (Followers: 12, SJR: 0.141, h-index: 7)
Annals of Clinical Biochemistry     Hybrid Journal   (Followers: 7, SJR: 0.687, h-index: 65)
Annals of Otology, Rhinology & Laryngology     Hybrid Journal   (Followers: 14, SJR: 0.727, h-index: 68)
Annals of Pharmacotherapy     Hybrid Journal   (Followers: 35, SJR: 0.863, h-index: 92)
Annals of the American Academy of Political and Social Science     Hybrid Journal   (Followers: 39, SJR: 1.164, h-index: 64)
Annals of the ICRP     Hybrid Journal   (Followers: 5, SJR: 1.272, h-index: 26)
Anthropocene Review     Hybrid Journal   (Followers: 7)
Anthropological Theory     Hybrid Journal   (Followers: 39, SJR: 1.767, h-index: 33)
Antitrust Bulletin     Full-text available via subscription   (Followers: 10)
Antiviral Chemistry and Chemotherapy     Hybrid Journal   (SJR: 0.591, h-index: 42)
Antyajaa : Indian J. of Women and Social Change     Hybrid Journal  
Applied Biosafety     Hybrid Journal  
Applied Psychological Measurement     Hybrid Journal   (Followers: 19, SJR: 1.721, h-index: 47)
Applied Spectroscopy     Full-text available via subscription   (Followers: 23, SJR: 0.668, h-index: 89)
Armed Forces & Society     Hybrid Journal   (Followers: 17, SJR: 0.482, h-index: 28)
Arts and Humanities in Higher Education     Hybrid Journal   (Followers: 33, SJR: 0.281, h-index: 17)
Asia Pacific Media Educator     Hybrid Journal   (Followers: 1)
Asia-Pacific J. of Management Research and Innovation     Full-text available via subscription   (Followers: 2)
Asia-Pacific J. of Public Health     Hybrid Journal   (Followers: 8, SJR: 0.572, h-index: 22)
Asian and Pacific Migration J.     Full-text available via subscription   (Followers: 43, SJR: 0.253, h-index: 20)
Asian Cardiovascular and Thoracic Annals     Hybrid Journal   (Followers: 2, SJR: 0.264, h-index: 19)
Asian J. of Comparative Politics     Hybrid Journal   (Followers: 4)
Asian J. of Legal Education     Full-text available via subscription   (Followers: 5)
Asian J. of Management Cases     Hybrid Journal   (Followers: 5, SJR: 0.113, h-index: 2)
ASN Neuro     Open Access   (Followers: 2, SJR: 1.286, h-index: 25)
Assessment     Hybrid Journal   (Followers: 10, SJR: 1.514, h-index: 58)
Assessment for Effective Intervention     Hybrid Journal   (Followers: 15, SJR: 0.531, h-index: 9)
Australasian Psychiatry     Hybrid Journal   (Followers: 9, SJR: 0.304, h-index: 28)
Australian & New Zealand J. of Psychiatry     Hybrid Journal   (Followers: 20, SJR: 1.269, h-index: 84)
Australian and New Zealand J. of Criminology     Hybrid Journal   (Followers: 472, SJR: 0.352, h-index: 25)
Australian J. of Career Development     Hybrid Journal   (Followers: 2)
Australian J. of Education     Hybrid Journal   (Followers: 30, SJR: 0.39, h-index: 21)
Australian J. of Management     Hybrid Journal   (Followers: 12, SJR: 0.841, h-index: 16)
Autism     Hybrid Journal   (Followers: 192, SJR: 1.35, h-index: 64)
Autism & Developmental Language Impairments     Open Access   (Followers: 4)
Behavior Modification     Hybrid Journal   (Followers: 10, SJR: 0.769, h-index: 60)
Behavioral and Cognitive Neuroscience Reviews     Hybrid Journal   (Followers: 20)
Bible Translator     Hybrid Journal   (Followers: 9)
Biblical Theology Bulletin     Hybrid Journal   (Followers: 14, SJR: 0.155, h-index: 10)
Big Data & Society     Open Access   (Followers: 29)
Biochemistry Insights     Open Access   (Followers: 6)
Bioinformatics and Biology Insights     Open Access   (Followers: 15, SJR: 0.682, h-index: 11)
Biological Research for Nursing     Hybrid Journal   (Followers: 7, SJR: 0.696, h-index: 33)
Biomarker Insights     Open Access   (Followers: 1, SJR: 0.713, h-index: 16)
Bioscope: South Asian Screen Studies     Hybrid Journal   (Followers: 3, SJR: 0.101, h-index: 4)
BMS: Bulletin of Sociological Methodology/Bulletin de Méthodologie Sociologique     Hybrid Journal   (Followers: 2, SJR: 0.143, h-index: 2)
Body & Society     Hybrid Journal   (Followers: 22, SJR: 0.883, h-index: 30)
Bone and Tissue Regeneration Insights     Open Access   (Followers: 2)
Breast Cancer : Basic and Clinical Research     Open Access   (Followers: 8, SJR: 0.758, h-index: 11)
British J. of Music Therapy     Hybrid Journal   (Followers: 4)
British J. of Occupational Therapy     Hybrid Journal   (Followers: 93, SJR: 0.403, h-index: 34)
British J. of Pain     Hybrid Journal   (Followers: 19)
British J. of Politics and Intl. Relations     Hybrid Journal   (Followers: 26, SJR: 1.021, h-index: 25)
British J. of Visual Impairment     Hybrid Journal   (Followers: 12, SJR: 0.261, h-index: 2)
British J.ism Review     Hybrid Journal   (Followers: 17)
Building Acoustics     Hybrid Journal   (Followers: 3, SJR: 0.373, h-index: 15)
Building Services Engineering Research & Technology     Hybrid Journal   (Followers: 3, SJR: 0.369, h-index: 23)
Bulletin of Science, Technology & Society     Hybrid Journal   (Followers: 5)
Business & Society     Hybrid Journal   (Followers: 9, SJR: 0.884, h-index: 36)
Business and Professional Communication Quarterly     Hybrid Journal   (Followers: 7, SJR: 0.444, h-index: 16)
Business Information Review     Hybrid Journal   (Followers: 14, SJR: 0.223, h-index: 9)
Business Perspectives and Research     Hybrid Journal   (Followers: 1)
Cahiers Élisabéthains     Hybrid Journal   (Followers: 1, SJR: 0.101, h-index: 2)
Calcutta Statistical Association Bulletin     Full-text available via subscription  
California Management Review     Hybrid Journal   (Followers: 24, SJR: 1.571, h-index: 96)
Canadian J. of Kidney Health and Disease     Open Access   (Followers: 5)
Canadian J. of Nursing Research (CJNR)     Hybrid Journal   (Followers: 13, SJR: 0.321, h-index: 33)
Canadian J. of Occupational Therapy     Hybrid Journal   (Followers: 77, SJR: 0.676, h-index: 41)
Canadian J. of Psychiatry     Hybrid Journal   (Followers: 20, SJR: 1.631, h-index: 87)
Canadian J. of School Psychology     Hybrid Journal   (Followers: 9, SJR: 0.297, h-index: 14)
Canadian Pharmacists J. / Revue des Pharmaciens du Canada     Hybrid Journal   (Followers: 2, SJR: 0.276, h-index: 12)
Cancer Growth and Metastasis     Open Access  
Cancer Informatics     Open Access   (Followers: 4, SJR: 0.686, h-index: 20)
Capital and Class     Hybrid Journal   (Followers: 9, SJR: 0.701, h-index: 6)
Cardiac Cath Lab Director     Full-text available via subscription  
Cardiovascular and Thoracic Open     Open Access  
Career Development and Transition for Exceptional Individuals     Hybrid Journal   (Followers: 7)
Cartilage     Hybrid Journal   (Followers: 7, SJR: 0.41, h-index: 16)
Cephalalgia     Hybrid Journal   (Followers: 6, SJR: 1.882, h-index: 101)
Child Language Teaching and Therapy     Hybrid Journal   (Followers: 25, SJR: 0.564, h-index: 20)
Child Maltreatment     Hybrid Journal   (Followers: 8, SJR: 1.246, h-index: 60)
Child Neurology Open     Open Access   (Followers: 4)
Childhood     Hybrid Journal   (Followers: 17, SJR: 0.572, h-index: 42)
Childhood Obesity and Nutrition     Open Access   (Followers: 11)
China Information     Hybrid Journal   (Followers: 6, SJR: 0.491, h-index: 12)
China Report     Hybrid Journal   (Followers: 10, SJR: 0.18, h-index: 6)
Chinese J. of Sociology     Full-text available via subscription   (Followers: 5)
Christianity & Literature     Full-text available via subscription   (Followers: 7)
Chronic Illness     Hybrid Journal   (Followers: 7, SJR: 0.695, h-index: 27)
Chronic Respiratory Disease     Hybrid Journal   (Followers: 6, SJR: 0.897, h-index: 28)
Citizenship, Social and Economics Education     Full-text available via subscription   (Followers: 5, SJR: 0.136, h-index: 2)
Clin-Alert     Hybrid Journal   (Followers: 1)
Clinical and Applied Thrombosis/Hemostasis     Hybrid Journal   (Followers: 13, SJR: 0.517, h-index: 42)
Clinical Case Studies     Hybrid Journal   (Followers: 2, SJR: 0.177, h-index: 12)
Clinical Child Psychology and Psychiatry     Hybrid Journal   (Followers: 40, SJR: 0.429, h-index: 38)
Clinical EEG and Neuroscience     Hybrid Journal   (Followers: 4, SJR: 0.719, h-index: 40)
Clinical Ethics     Hybrid Journal   (Followers: 8, SJR: 0.285, h-index: 5)
Clinical Medicine Insights : Arthritis and Musculoskeletal Disorders     Open Access   (Followers: 2, SJR: 0.579, h-index: 10)
Clinical Medicine Insights : Case Reports     Open Access   (Followers: 1, SJR: 0.193, h-index: 6)
Clinical Medicine Insights : Circulatory, Respiratory and Pulmonary Medicine     Open Access   (Followers: 3, SJR: 0.232, h-index: 8)
Clinical Medicine Insights : Ear, Nose and Throat     Open Access   (Followers: 1)
Clinical Medicine Insights : Endocrinology and Diabetes     Open Access   (Followers: 26, SJR: 0.458, h-index: 7)
Clinical Medicine Insights : Oncology     Open Access   (Followers: 4, SJR: 0.796, h-index: 14)
Clinical Medicine Insights : Pathology     Open Access   (Followers: 2, SJR: 0.387, h-index: 5)
Clinical Medicine Insights : Pediatrics     Open Access   (Followers: 3)
Clinical Nursing Research     Hybrid Journal   (Followers: 27, SJR: 0.474, h-index: 32)
Clinical Pediatrics     Hybrid Journal   (Followers: 17, SJR: 0.456, h-index: 51)
Clinical Psychological Science     Hybrid Journal   (Followers: 11, SJR: 3.112, h-index: 14)
Clinical Rehabilitation     Hybrid Journal   (Followers: 63, SJR: 1.149, h-index: 79)
Clinical Risk     Hybrid Journal   (Followers: 7, SJR: 0.16, h-index: 9)
Clinical Trials     Hybrid Journal   (Followers: 21, SJR: 1.542, h-index: 43)
Clothing and Textiles Research J.     Hybrid Journal   (Followers: 19, SJR: 0.509, h-index: 23)
Common Law World Review     Full-text available via subscription   (Followers: 16)
Communication & Sport     Hybrid Journal   (Followers: 5)
Communication and the Public     Hybrid Journal  
Communication Disorders Quarterly     Hybrid Journal   (Followers: 14, SJR: 0.335, h-index: 11)
Communication Research     Hybrid Journal   (Followers: 19, SJR: 1.935, h-index: 72)
Community College Review     Hybrid Journal   (Followers: 7, SJR: 0.779, h-index: 14)
Comparative Political Studies     Hybrid Journal   (Followers: 147, SJR: 2.77, h-index: 69)
Compensation & Benefits Review     Hybrid Journal   (Followers: 7)
Competition & Change     Hybrid Journal   (Followers: 10, SJR: 0.585, h-index: 6)
Competition and Regulation in Network Industries     Full-text available via subscription   (Followers: 8, SJR: 0.413, h-index: 2)
Concurrent Engineering     Hybrid Journal   (Followers: 3, SJR: 0.565, h-index: 33)
Conflict Management and Peace Science     Hybrid Journal   (Followers: 28, SJR: 1.151, h-index: 28)
Contemporary Drug Problems     Full-text available via subscription   (Followers: 3)
Contemporary Education Dialogue     Hybrid Journal   (Followers: 5)
Contemporary Issues in Early Childhood     Full-text available via subscription   (Followers: 5, SJR: 0.449, h-index: 13)
Contemporary Review of the Middle East     Full-text available via subscription   (Followers: 3)
Contemporary Sociology : A J. of Reviews     Full-text available via subscription   (Followers: 27, SJR: 0.11, h-index: 18)
Contemporary Voice of Dalit     Full-text available via subscription  
Contexts     Hybrid Journal   (Followers: 3)
Contributions to Indian Sociology     Hybrid Journal   (Followers: 4, SJR: 0.363, h-index: 17)
Convergence The Intl. J. of Research into New Media Technologies     Hybrid Journal   (Followers: 47, SJR: 0.844, h-index: 25)
Cooperation and Conflict     Hybrid Journal   (Followers: 13, SJR: 0.856, h-index: 22)
Cornell Hospitality Quarterly     Hybrid Journal   (Followers: 8, SJR: 1.862, h-index: 47)
Counseling Outcome Research and Evaluation     Hybrid Journal   (Followers: 10)
Counseling Psychologist     Hybrid Journal   (Followers: 14, SJR: 0.567, h-index: 60)
Crime & Delinquency     Hybrid Journal   (Followers: 69, SJR: 1.327, h-index: 51)
Crime, Media, Culture     Hybrid Journal   (Followers: 15, SJR: 0.753, h-index: 19)
Criminal Justice and Behavior     Hybrid Journal   (Followers: 47, SJR: 1.193, h-index: 66)
Criminal Justice Policy Review     Hybrid Journal   (Followers: 32, SJR: 0.564, h-index: 15)
Criminal Justice Review     Hybrid Journal   (Followers: 13, SJR: 0.498, h-index: 19)
Criminology and Criminal Justice     Hybrid Journal   (Followers: 51, SJR: 0.718, h-index: 25)
Critical Research on Religion     Hybrid Journal   (Followers: 6)
Critical Reviews in Oral Biology Medicine     Hybrid Journal   (Followers: 1)
Critical Social Policy     Hybrid Journal   (Followers: 33, SJR: 1.063, h-index: 43)
Critical Sociology     Hybrid Journal   (Followers: 28, SJR: 0.584, h-index: 19)
Critical Studies in Television: scholarly studies in small screen fictions     Full-text available via subscription   (Followers: 12)
Critique of Anthropology     Hybrid Journal   (Followers: 37, SJR: 0.723, h-index: 31)
Cross-Cultural Research     Hybrid Journal   (Followers: 7, SJR: 0.707, h-index: 29)
Cultural Dynamics     Hybrid Journal   (Followers: 5, SJR: 0.107, h-index: 19)
Cultural Geographies     Hybrid Journal   (Followers: 18, SJR: 1.531, h-index: 37)
Cultural Sociology     Hybrid Journal   (Followers: 32, SJR: 0.713, h-index: 19)
Cultural Studies - Critical Methodologies     Hybrid Journal   (Followers: 15, SJR: 0.314, h-index: 18)
Culture & Psychology     Hybrid Journal   (Followers: 12, SJR: 0.41, h-index: 33)

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Journal Cover Cancer Informatics
  [SJR: 0.686]   [H-I: 20]   [4 followers]  Follow
    
  This is an Open Access Journal Open Access journal
   ISSN (Print) 1176-9351
   Published by Sage Publications Homepage  [998 journals]
  • Gene-Set Reduction for Analysis of Major and Minor Gleason Scores Based on
           Differential Gene-Set Expressions and Biological Pathways in Prostate
           Cancer

    • Authors: Irina Dinu, Surya Poudel, Saumyadipta Pyne
      Abstract: The Gleason score (GS) plays an important role in prostate cancer detection and treatment. It is calculated based on a sum between its major and minor components, each ranging from 1 to 5, assigned after examination of sample cells taken from each side of the prostate gland during biopsy. A total GS of at least 7 is associated with more aggressive prostate cancer. However, it is still unclear ...
      Citation: Cancer Informatics 2017:16 1176935117730016
      PubDate: 2017-09-11T00:00:00-05:00
      DOI: 10.4137/CIN.S41996
      Issue No: Vol. 2017, No. 1 (2017)
       
  • xSyn: A Software Tool for Identifying Sophisticated 3-Way Interactions
           From Cancer Expression Data

    • Authors: Baishali Bandyopadhyay, Veda Chanda, Yupeng Wang
      Abstract: Background:Constructing gene co-expression networks from cancer expression data is important for investigating the genetic mechanisms underlying cancer. However, correlation coefficients or linear regression models are not able to model sophisticated relationships among gene expression profiles. Here, we address the 3-way interaction that 2 genes’ expression levels are clustered in ...
      Citation: Cancer Informatics 2017:16 1176935117728516
      PubDate: 2017-08-28T00:00:00-05:00
      DOI: 10.4137/CIN.S42590
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Adaptive Multiview Nonnegative Matrix Factorization Algorithm for
           Integration of Multimodal Biomedical Data

    • Authors: Bisakha Ray, Wenke Liu, David Fenyö
      Abstract: The amounts and types of available multimodal tumor data are rapidly increasing, and their integration is critical for fully understanding the underlying cancer biology and personalizing treatment. However, the development of methods for effectively integrating multimodal data in a principled manner is lagging behind our ability to generate the data. In this article, we introduce an extension ...
      Citation: Cancer Informatics 2017:16 1176935117725727
      PubDate: 2017-08-18T00:00:00-05:00
      DOI: 10.4137/CIN.S42223
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Immuno-Oncology Integrative Networks: Elucidating the Influences of
           Osteosarcoma Phenotypes

    • Authors: Ankush Sharma, Enrico Capobianco
      Abstract: In vivo and in vitro functional phenotyping characterization was recently obtained with reference to an experimental pan-cancer study of 22 osteosarcoma (OS) cell lines. Here, differentially expressed gene (DEG) profiles were recomputed from the publicly available data to conduct network inference on the immune system regulatory activity across the characterized OS phenotypes. Based on such DE ...
      Citation: Cancer Informatics 2017:16 1176935117721691
      PubDate: 2017-07-26T00:00:00-05:00
      DOI: 10.4137/CIN.S41170
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Prediction With Dimension Reduction of Multiple Molecular Data Sources for
           Patient Survival

    • Authors: Adam Kaplan, Eric F Lock
      Abstract: Predictive modeling from high-dimensional genomic data is often preceded by a dimension reduction step, such as principal component analysis (PCA). However, the application of PCA is not straightforward for multisource data, wherein multiple sources of ‘omics data measure different but related biological components. In this article, we use recent advances in the dimension reduction of ...
      Citation: Cancer Informatics 2017:16 1176935117718517
      PubDate: 2017-07-11T00:00:00-05:00
      DOI: 10.4137/CIN.S42339
      Issue No: Vol. 2017, No. 1 (2017)
       
  • The Impact of Collisions on the Ability to Detect Rare Mutant Alleles
           Using Barcode-Type Next-Generation Sequencing Techniques

    • Authors: Jenna VanLiere Canzoniero, Karen Cravero, Ben Ho Park
      Abstract: Barcoding techniques are used to reduce error from next-generation sequencing, with applications ranging from understanding tumor subclone populations to detecting circulating tumor DNA. Collisions occur when more than one sample molecule is tagged by the same unique identifier (UID) and can result in failure to detect very-low-frequency mutations and error in estimating mutation frequency. He ...
      Citation: Cancer Informatics 2017:16 1176935117719236
      PubDate: 2017-07-10T00:00:00-05:00
      DOI: 10.4137/CIN.S42168
      Issue No: Vol. 2017, No. 1 (2017)
       
  • An Assessment of Database-Validated microRNA Target Genes in Normal
           Colonic Mucosa: Implications for Pathway Analysis

    • Authors: Martha L Slattery, Jennifer S Herrick, John R Stevens, Roger K Wolff, Lila E Mullany
      Abstract: Background:Determination of functional pathways regulated by microRNAs (miRNAs), while an essential step in developing therapeutics, is challenging. Some miRNAs have been studied extensively; others have limited information. In this study, we focus on 254 miRNAs previously identified as being associated with colorectal cancer and their database-identified validated target genes. ...
      Citation: Cancer Informatics 2017:16 1176935117716405
      PubDate: 2017-06-23T00:00:00-05:00
      DOI: 10.4137/CIN.S42077
      Issue No: Vol. 2017, No. 1 (2017)
       
  • A Software Application for Mining and Presenting Relevant Cancer Clinical
           Trials per Cancer Mutation

    • Authors: Lisa M Gandy, Jordan Gumm, Amanda L Blackford, Elana J Fertig, Luis A Diaz
      Abstract: ClinicalTrials.org is a popular portal which physicians use to find clinical trials for their patients. However, the current setup of ClinicalTrials.org makes it difficult for oncologists to locate clinical trials for patients based on mutational status. We present CTMine, a system that mines ClinicalTrials.org for clinical trials per cancer mutation and displays the trials in a user-friendly ...
      Citation: Cancer Informatics 2017:16 1176935117711940
      PubDate: 2017-06-22T00:00:00-05:00
      DOI: 10.4137/CIN.S41353
      Issue No: Vol. 2017, No. 1 (2017)
       
  • The Model-Based Study of the Effectiveness of Reporting Lists of Small
           Feature Sets Using RNA-Seq Data

    • Authors: Eunji Kim, Ivan Ivanov, Jianping Hua, Johanna W Lampe, Meredith AJ Hullar, Robert S Chapkin, Edward R Dougherty
      Abstract: Ranking feature sets for phenotype classification based on gene expression is a challenging issue in cancer bioinformatics. When the number of samples is small, all feature selection algorithms are known to be unreliable, producing significant error, and error estimators suffer from different degrees of imprecision. The problem is compounded by the fact that the accuracy of classification depe ...
      Citation: Cancer Informatics 2017:16 1176935117710530
      PubDate: 2017-06-12T00:00:00-05:00
      DOI: 10.4137/CIN.S41650
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Tumor RAS Gene Expression Levels Are Influenced by the Mutational Status
           of RAS Genes and Both Upstream and Downstream RAS Pathway Genes

    • Authors: Robert M Stephens, Ming Yi, Bailey Kessing, Dwight V Nissley, Frank McCormick
      Abstract: The 3 human RAS genes play pivotal roles regulating proliferation, differentiation, and survival in normal cells and become mutated in 15% to 20% of all human tumors and amplified in many others. In this report, we examined data from The Cancer Genome Atlas to investigate the relationship between RAS gene mutational status and messenger RNA expression. We show that all 3 RAS genes exhibit incr ...
      Citation: Cancer Informatics 2017:16 1176935117711944
      PubDate: 2017-06-08T00:00:00-05:00
      DOI: 10.4137/CIN.S41745
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Lung Cancer Pathological Image Analysis Using a Hidden Potts Model

    • Authors: Qianyun Li, Faliu Yi, Tao Wang, Guanghua Xiao, Faming Liang
      Abstract: Nowadays, many biological data are acquired via images. In this article, we study the pathological images scanned from 205 patients with lung cancer with the goal to find out the relationship between the survival time and the spatial distribution of different types of cells, including lymphocyte, stroma, and tumor cells. Toward this goal, we model the spatial distribution of different types of ...
      Citation: Cancer Informatics 2017:16 1176935117711910
      PubDate: 2017-06-05T00:00:00-05:00
      DOI: 10.4137/CIN.S41524
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Immune Checkpoint Inhibition and the Prevalence of Autoimmune Disorders
           Among Patients With Lung and Renal Cancer

    • Authors: Sherif M El-Refai, Joshua D Brown, Esther P Black, Jeffery C Talbert
      Abstract: Purpose:Immune checkpoint inhibition reactivates the immune response against cancer cells in multiple tissue types and has been shown to induce durable responses. However, for patients with autoimmune disorders, their conditions can worsen with this reactivation. We sought to identify, among patients with lung and renal cancer, how many harbor a comorbid autoimmune condition and may b ...
      Citation: Cancer Informatics 2017:16 1176935117712520
      PubDate: 2017-06-01T00:00:00-05:00
      DOI: 10.4137/CIN.S42039
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Sequence Analysis and Phylogenetic Studies of Hypoxia-Inducible
           Factor-1α

    • Authors: Jagadeesha Poyya, Chandrashekhar G Joshi, D Jagadeesha Kumar, HG Nagendra
      Abstract: Hypoxia-inducible factors (HIF) belong to the basic helix loop helix–PER ARNT SIM (bHLH-PAS) family of transcription factors that induce metabolic reprogramming under hypoxic condition. The phylogenetic studies of hypoxia-inducible factor-1α (HIF-1α) sequences across different organisms/species may leave a clue on the evolutionary relationships and its probable correlation to tumorigenesis ...
      Citation: Cancer Informatics 2017:16 1176935117712242
      PubDate: 2017-05-31T00:00:00-05:00
      DOI: 10.4137/CIN.S41860
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Quantitative Study of Thermal Disturbances Due to Nonuniformly Perfused
           Tumors in Peripheral Regions of Women’s Breast

    • Authors: Akshara Makrariya, Neeru Adlakha
      Abstract: Background:Mathematical modeling of biothermal processes is widely used to enhance the quantitative understanding of thermoregulation system of human body organs. This quantitative knowledge of thermal information of various human body organs can be used for developing clinical applications. In the past, investigators have studied thermal distribution in hemisphere-shaped human breast ...
      Citation: Cancer Informatics 2017:16 1176935117700894
      PubDate: 2017-05-15T00:00:00-05:00
      DOI: 10.4137/CIN.S41183
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Time-Based Switching Control of Genetic Regulatory Networks: Toward
           Sequential Drug Intake for Cancer Therapy

    • Authors: Wasiu Opeyemi Oduola, Xiangfang Li, Chang Duan, Lijun Qian, Fen Wu, Edward R Dougherty
      Abstract: As cancer growth and development typically involves multiple genes and pathways, combination therapy has been touted as the standard of care in the treatment of cancer. However, drug toxicity becomes a major concern whenever a patient takes 2 or more drugs simultaneously at the maximum tolerable dosage. A potential solution would be administering the drugs in a sequential or alternating manner ...
      Citation: Cancer Informatics 2017:16 1176935117706888
      PubDate: 2017-05-10T00:00:00-05:00
      DOI: 10.4137/CIN.S41253
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Applying Multivariate Adaptive Splines to Identify Genes With Expressions
           Varying After Diagnosis in Microarray Experiments

    • Authors: Fenghai Duan, Ye Xu
      Abstract: Purpose:To analyze a microarray experiment to identify the genes with expressions varying after the diagnosis of breast cancer.Methods:A total of 44 928 probe sets in an Affymetrix microarray data publicly available on Gene Expression Omnibus from 249 patients with breast cancer were analyzed by the nonparametric multivariate adaptive splines. Then, the identified ge ...
      Citation: Cancer Informatics 2017:16 1176935117705381
      PubDate: 2017-05-04T00:00:00-05:00
      DOI: 10.4137/CIN.S13977
      Issue No: Vol. 2017, No. 1 (2017)
       
  • miR-10a and miR-204 as a Potential Prognostic Indicator in Low-Grade
           Gliomas

    • Authors: Ju Cheol. Son, Hyoung Oh. Jeong, Deaui. Park, Sang Gyoon. No, Eun Kyeong. Lee, Jaewon. Lee, Hae Young. Chung
      Abstract: This study aimed to identify and characterize microRNAs (miRNAs) that are related to radiosensitivity in low-grade gliomas (LGGs). The miRNA expression levels in radiosensitive and radioresistant LGGs were compared using The Cancer Genome Atlas database, and differentially expressed miRNAs were identified using the EBSeq package. The miRNA target genes were predicted using Web databases. Fifte ...
      Citation: Cancer Informatics 2017:16 1176935117702878
      PubDate: 2017-04-12T00:00:00-05:00
      DOI: 10.4137/CIN.S41605
      Issue No: Vol. 2017, No. 1 (2017)
       
  • A mixture copula Bayesian network model for multimodal genomic data

    • Authors: Qingyang. Zhang, Xuan. Shi
      Abstract: Gaussian Bayesian networks have become a widely used framework to estimate directed associations between joint Gaussian variables, where the network structure encodes the decomposition of multivariate normal density into local terms. However, the resulting estimates can be inaccurate when the normality assumption is moderately or severely violated, making it unsuitable for dealing with recent ...
      Citation: Cancer Informatics 2017:16 1176935117702389
      PubDate: 2017-04-12T00:00:00-05:00
      DOI: 10.4137/CIN.S41168
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Bioinformatics Education in Pathology Training: Current Scope and Future
           Direction

    • Authors: Michael R. Clay, Kevin E. Fisher
      Abstract: Training anatomic and clinical pathology residents in the principles of bioinformatics is a challenging endeavor. Most residents receive little to no formal exposure to bioinformatics during medical education, and most of the pathology training is spent interpreting histopathology slides using light microscopy or focused on laboratory regulation, management, and interpretation of discrete labo ...
      Citation: Cancer Informatics 2017:16 1176935117703389
      PubDate: 2017-04-10T00:00:00-05:00
      DOI: 10.4137/CIN.S41261
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Therapeutic Interventions of Cancers Using Intrinsically Disordered
           Proteins as Drug Targets: c-Myc as Model System

    • Authors: Deepak. Kumar, Nitin. Sharma, Rajanish. Giri
      Abstract: The concept of protein intrinsic disorder has taken the driving seat to understand regulatory proteins in general. Reports suggest that in mammals nearly 75% of signalling proteins contain long disordered regions with greater than 30 amino acid residues. Therefore, intrinsically disordered proteins (IDPs) have been implicated in several human diseases and should be considered as potential nove ...
      Citation: Cancer Informatics 2017:16 1176935117699408
      PubDate: 2017-03-16T00:00:00-05:00
      DOI: 10.4137/CIN.S40869
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Roadmap to a Comprehensive Clinical Data Warehouse for Precision Medicine
           Applications in Oncology

    • Authors: David J. Foran, Wenjin. Chen, Huiqi. Chu, Evita. Sadimin, Doreen. Loh, Gregory. Riedlinger, Lauri A. Goodell, Shridar. Ganesan, Kim. Hirshfield, Lorna. Rodriguez, Robert S. DiPaola
      Abstract: Leading institutions throughout the country have established Precision Medicine programs to support personalized treatment of patients. A cornerstone for these programs is the establishment of enterprise-wide Clinical Data Warehouses. Working shoulder-to-shoulder, a team of physicians, systems biologists, engineers, and scientists at Rutgers Cancer Institute of New Jersey have designed, develo ...
      Citation: Cancer Informatics 2017:16 1176935117694349
      PubDate: 2017-03-02T00:00:00-06:00
      DOI: 10.4137/CIN.S41586
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Integrative Analysis of Gene Networks and Their Application to Lung
           Adenocarcinoma Studies

    • Authors: Sangin. Lee, Faming. Liang, Ling. Cai, Guanghua. Xiao
      Abstract: The construction of gene regulatory networks (GRNs) is an essential component of biomedical research to determine disease mechanisms and identify treatment targets. Gaussian graphical models (GGMs) have been widely used for constructing GRNs by inferring conditional dependence among a set of gene expressions. In practice, GRNs obtained by the analysis of a single data set may not be reliable d ...
      Citation: Cancer Informatics 2017:16 1176935117690778
      PubDate: 2017-02-23T00:00:00-06:00
      DOI: 10.4137/CIN.S40463
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Significant Prognostic Features and Patterns of Somatic Mutations in Human
           Cancers

    • Authors: Wensheng. Zhang, Andrea. Edwards, Erik K. Flemington, Kun. Zhang
      Abstract: TP53 is the most frequently altered gene in human cancers. Numerous retrospective studies have related its mutation and abnormal p53 protein expression to poor patient survival. Nonetheless, the clinical significance of TP53 (p53) status has been a controversial issue. In this work, we aimed to characterize TP53 somatic mutations in tumor cells across multipl ...
      Citation: Cancer Informatics 2017:16 1176935117691267
      PubDate: 2017-02-20T00:00:00-06:00
      DOI: 10.4137/CIN.S40884
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Improving Gastric Cancer Outcome Prediction Using Single Time-Point
           Artificial Neural Network Models

    • Authors: Hamid. Nilsaz-Dezfouli, Mohd Rizam. Abu-Bakar, Jayanthi. Arasan, Mohd Bakri. Adam, Mohamad Amin. Pourhoseingholi
      Abstract: In cancer studies, the prediction of cancer outcome based on a set of prognostic variables has been a long-standing topic of interest. Current statistical methods for survival analysis offer the possibility of modelling cancer survivability but require unrealistic assumptions about the survival time distribution or proportionality of hazard. Therefore, attention must be paid in developing nonl ...
      Citation: Cancer Informatics 2017:16 1176935116686062
      PubDate: 2017-02-16T00:00:00-06:00
      DOI: 10.4137/CIN.S40270
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Epithelial Ovarian Cancer Diagnosis of Second-Harmonic Generation Images:
           A Semiautomatic Collagen Fibers Quantification Protocol

    • Authors: Angel A. Zeitoune, Johana SJ. Luna, Kynthia. Sanchez Salas, Luciana. Erbes, Carlos L. Cesar, Liliana ALA. Andrade, Hernades F. Carvahlo, Fátima. Bottcher-Luiz, Victor H. Casco, Javier. Adur
      Abstract: A vast number of human pathologic conditions are directly or indirectly related to tissular collagen structure remodeling. The nonlinear optical microscopy second-harmonic generation has become a powerful tool for imaging biological tissues with anisotropic hyperpolarized structures, such as collagen. During the past years, several quantification methods to analyze and evaluate these images ha ...
      Citation: Cancer Informatics 2017:16 1176935117690162
      PubDate: 2017-02-03T00:00:00-06:00
      DOI: 10.4137/CIN.S41049
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Unified Least Squares Methods for the Evaluation of Diagnostic Tests With
           the Gold Standard

    • Authors: Liansheng Larry. Tang, Ao. Yuan, John. Collins, Xuan. Che, Leighton. Chan
      Abstract: The article proposes a unified least squares method to estimate the receiver operating characteristic (ROC) parameters for continuous and ordinal diagnostic tests, such as cancer biomarkers. The method is based on a linear model framework using the empirically estimated sensitivities and specificities as input “data.” It gives consistent estimates for regression and accuracy parameters whe ...
      Citation: Cancer Informatics 2017:16 1176935116686063
      PubDate: 2017-02-03T00:00:00-06:00
      DOI: 10.4137/CIN.S40532
      Issue No: Vol. 2017, No. 1 (2017)
       
  • A Numerical Handling of the Boundary Conditions Imposed by the Skull on an
           Inhomogeneous Diffusion-Reaction Model of Glioblastoma Invasion Into the
           Brain: Clinical Validation Aspects

    • Authors: Georgios S. Stamatakos, Stavroula G. Giatili
      Abstract: A novel explicit triscale reaction-diffusion numerical model of glioblastoma multiforme tumor growth is presented. The model incorporates the handling of Neumann boundary conditions imposed by the cranium and takes into account both the inhomogeneous nature of human brain and the complexity of the skull geometry. The finite-difference time-domain method is adopted. To demonstrate the workflow ...
      Citation: Cancer Informatics 2017:15 1176935116684824
      PubDate: 2017-02-03T00:00:00-06:00
      DOI: 10.4137/CIN.S39855
      Issue No: Vol. 2017, No. 1 (2017)
       
  • Identification of Genetic and Epigenetic Variants Associated with Breast
           Cancer Prognosis by Integrative Bioinformatics Analysis

    • Authors: Arunima Shilpi, Yingtao Bi, Segun Jung, Samir K. Patra, Ramana V. Davuluri
      Pages: 1 - 13
      Abstract: Introduction: Breast cancer being a multifaceted disease constitutes a wide spectrum of histological and molecular variability in tumors. However, the task for the identification of these variances is complicated by the interplay between inherited genetic and epigenetic aberrations. Therefore, this study provides an extrapolate outlook to the sinister partnership between DNA methylation and single ...
      Citation: Cancer Informatics 2017:16 1-13
      PubDate: 2017-01-09T00:00:00-06:00
      DOI: 10.4137/CIN.S39783
      Issue No: Vol. 2017, No. 1 (2017)
       
 
 
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