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Publisher: Oxford University Press   (Total: 370 journals)

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Showing 1 - 200 of 370 Journals sorted alphabetically
Acta Biochimica et Biophysica Sinica     Hybrid Journal   (Followers: 6, SJR: 0.881, h-index: 38)
Adaptation     Hybrid Journal   (Followers: 8, SJR: 0.111, h-index: 4)
Aesthetic Surgery J.     Hybrid Journal   (Followers: 6, SJR: 1.538, h-index: 35)
African Affairs     Hybrid Journal   (Followers: 60, SJR: 1.512, h-index: 46)
Age and Ageing     Hybrid Journal   (Followers: 84, SJR: 1.611, h-index: 107)
Alcohol and Alcoholism     Hybrid Journal   (Followers: 15, SJR: 0.935, h-index: 80)
American Entomologist     Full-text available via subscription   (Followers: 6)
American Historical Review     Hybrid Journal   (Followers: 129, SJR: 0.652, h-index: 43)
American J. of Agricultural Economics     Hybrid Journal   (Followers: 41, SJR: 1.441, h-index: 77)
American J. of Epidemiology     Hybrid Journal   (Followers: 159, SJR: 3.047, h-index: 201)
American J. of Hypertension     Hybrid Journal   (Followers: 23, SJR: 1.397, h-index: 111)
American J. of Jurisprudence     Hybrid Journal   (Followers: 16)
American J. of Legal History     Full-text available via subscription   (Followers: 5, SJR: 0.151, h-index: 7)
American Law and Economics Review     Hybrid Journal   (Followers: 25, SJR: 0.824, h-index: 23)
American Literary History     Hybrid Journal   (Followers: 12, SJR: 0.185, h-index: 22)
Analysis     Hybrid Journal   (Followers: 24)
Annals of Botany     Hybrid Journal   (Followers: 35, SJR: 1.912, h-index: 124)
Annals of Occupational Hygiene     Hybrid Journal   (Followers: 26, SJR: 0.837, h-index: 57)
Annals of Oncology     Hybrid Journal   (Followers: 47, SJR: 4.362, h-index: 173)
Annals of the Entomological Society of America     Full-text available via subscription   (Followers: 8, SJR: 0.642, h-index: 53)
Annals of Work Exposures and Health     Hybrid Journal  
AoB Plants     Open Access   (Followers: 3, SJR: 0.78, h-index: 10)
Applied Economic Perspectives and Policy     Hybrid Journal   (Followers: 19, SJR: 0.884, h-index: 31)
Applied Linguistics     Hybrid Journal   (Followers: 51, SJR: 1.749, h-index: 63)
Applied Mathematics Research eXpress     Hybrid Journal   (Followers: 1, SJR: 0.779, h-index: 11)
Arbitration Intl.     Full-text available via subscription   (Followers: 20)
Arbitration Law Reports and Review     Hybrid Journal   (Followers: 13)
Archives of Clinical Neuropsychology     Hybrid Journal   (Followers: 26, SJR: 0.96, h-index: 71)
Aristotelian Society Supplementary Volume     Hybrid Journal   (Followers: 2, SJR: 0.102, h-index: 20)
Arthropod Management Tests     Hybrid Journal   (Followers: 2)
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Biology of Reproduction     Full-text available via subscription   (Followers: 9, SJR: 1.646, h-index: 149)
Biometrika     Hybrid Journal   (Followers: 19, SJR: 2.801, h-index: 90)
BioScience     Hybrid Journal   (Followers: 28, SJR: 2.374, h-index: 154)
Bioscience Horizons : The National Undergraduate Research J.     Open Access   (Followers: 1, SJR: 0.213, h-index: 9)
Biostatistics     Hybrid Journal   (Followers: 16, SJR: 1.955, h-index: 55)
BJA : British J. of Anaesthesia     Hybrid Journal   (Followers: 142, SJR: 2.314, h-index: 133)
BJA Education     Hybrid Journal   (Followers: 66, SJR: 0.272, h-index: 20)
Brain     Hybrid Journal   (Followers: 60, SJR: 6.097, h-index: 264)
Briefings in Bioinformatics     Hybrid Journal   (Followers: 45, SJR: 4.086, h-index: 73)
Briefings in Functional Genomics     Hybrid Journal   (Followers: 4, SJR: 1.771, h-index: 50)
British J. for the Philosophy of Science     Hybrid Journal   (Followers: 34, SJR: 1.267, h-index: 38)
British J. of Aesthetics     Hybrid Journal   (Followers: 25, SJR: 0.217, h-index: 18)
British J. of Criminology     Hybrid Journal   (Followers: 524, SJR: 1.373, h-index: 62)
British J. of Social Work     Hybrid Journal   (Followers: 82, SJR: 0.771, h-index: 53)
British Medical Bulletin     Hybrid Journal   (Followers: 7, SJR: 1.391, h-index: 84)
British Yearbook of Intl. Law     Hybrid Journal   (Followers: 27)
Bulletin of the London Mathematical Society     Hybrid Journal   (Followers: 3, SJR: 1.474, h-index: 31)
Cambridge J. of Economics     Hybrid Journal   (Followers: 58, SJR: 0.957, h-index: 59)
Cambridge J. of Regions, Economy and Society     Hybrid Journal   (Followers: 11, SJR: 1.067, h-index: 22)
Cambridge Quarterly     Hybrid Journal   (Followers: 11, SJR: 0.1, h-index: 7)
Capital Markets Law J.     Hybrid Journal  
Carcinogenesis     Hybrid Journal   (Followers: 2, SJR: 2.439, h-index: 167)
Cardiovascular Research     Hybrid Journal   (Followers: 11, SJR: 2.897, h-index: 175)
Cerebral Cortex     Hybrid Journal   (Followers: 40, SJR: 4.827, h-index: 192)
CESifo Economic Studies     Hybrid Journal   (Followers: 16, SJR: 0.501, h-index: 19)
Chemical Senses     Hybrid Journal   (Followers: 1, SJR: 1.436, h-index: 76)
Children and Schools     Hybrid Journal   (Followers: 6, SJR: 0.211, h-index: 18)
Chinese J. of Comparative Law     Hybrid Journal   (Followers: 3)
Chinese J. of Intl. Law     Hybrid Journal   (Followers: 21, SJR: 0.737, h-index: 11)
Chinese J. of Intl. Politics     Hybrid Journal   (Followers: 8, SJR: 1.238, h-index: 15)
Christian Bioethics: Non-Ecumenical Studies in Medical Morality     Hybrid Journal   (Followers: 11, SJR: 0.191, h-index: 8)
Classical Receptions J.     Hybrid Journal   (Followers: 19, SJR: 0.1, h-index: 3)
Clinical Infectious Diseases     Hybrid Journal   (Followers: 58, SJR: 4.742, h-index: 261)
Clinical Kidney J.     Open Access   (Followers: 4, SJR: 0.338, h-index: 19)
Community Development J.     Hybrid Journal   (Followers: 24, SJR: 0.47, h-index: 28)
Computer J.     Hybrid Journal   (Followers: 7, SJR: 0.371, h-index: 47)
Conservation Physiology     Open Access   (Followers: 2)
Contemporary Women's Writing     Hybrid Journal   (Followers: 11, SJR: 0.111, h-index: 3)
Contributions to Political Economy     Hybrid Journal   (Followers: 6, SJR: 0.313, h-index: 10)
Critical Values     Full-text available via subscription  
Current Legal Problems     Hybrid Journal   (Followers: 26)
Current Zoology     Full-text available via subscription   (SJR: 0.999, h-index: 20)
Database : The J. of Biological Databases and Curation     Open Access   (Followers: 11, SJR: 1.068, h-index: 24)
Digital Scholarship in the Humanities     Hybrid Journal   (Followers: 12)
Diplomatic History     Hybrid Journal   (Followers: 18, SJR: 0.296, h-index: 22)
DNA Research     Open Access   (Followers: 4, SJR: 2.42, h-index: 77)
Dynamics and Statistics of the Climate System     Open Access   (Followers: 3)
Early Music     Hybrid Journal   (Followers: 14, SJR: 0.124, h-index: 11)
Economic Policy     Hybrid Journal   (Followers: 59, SJR: 2.052, h-index: 52)
ELT J.     Hybrid Journal   (Followers: 25, SJR: 1.26, h-index: 23)
English Historical Review     Hybrid Journal   (Followers: 48, SJR: 0.311, h-index: 10)
English: J. of the English Association     Hybrid Journal   (Followers: 13, SJR: 0.144, h-index: 3)
Environmental Entomology     Full-text available via subscription   (Followers: 11, SJR: 0.791, h-index: 66)
Environmental Epigenetics     Open Access   (Followers: 1)
Environmental History     Hybrid Journal   (Followers: 26, SJR: 0.197, h-index: 25)
EP-Europace     Hybrid Journal   (Followers: 2, SJR: 2.201, h-index: 71)
Epidemiologic Reviews     Hybrid Journal   (Followers: 10, SJR: 3.917, h-index: 81)
ESHRE Monographs     Hybrid Journal  
Essays in Criticism     Hybrid Journal   (Followers: 16, SJR: 0.1, h-index: 6)
European Heart J.     Hybrid Journal   (Followers: 49, SJR: 6.997, h-index: 227)
European Heart J. - Cardiovascular Imaging     Hybrid Journal   (Followers: 9, SJR: 2.044, h-index: 58)
European Heart J. - Cardiovascular Pharmacotherapy     Full-text available via subscription   (Followers: 1)
European Heart J. - Quality of Care and Clinical Outcomes     Hybrid Journal  
European Heart J. Supplements     Hybrid Journal   (Followers: 8, SJR: 0.152, h-index: 31)
European J. of Cardio-Thoracic Surgery     Hybrid Journal   (Followers: 8, SJR: 1.568, h-index: 104)
European J. of Intl. Law     Hybrid Journal   (Followers: 152, SJR: 0.722, h-index: 38)
European J. of Orthodontics     Hybrid Journal   (Followers: 4, SJR: 1.09, h-index: 60)
European J. of Public Health     Hybrid Journal   (Followers: 22, SJR: 1.284, h-index: 64)
European Review of Agricultural Economics     Hybrid Journal   (Followers: 12, SJR: 1.549, h-index: 42)
European Review of Economic History     Hybrid Journal   (Followers: 28, SJR: 0.628, h-index: 24)
European Sociological Review     Hybrid Journal   (Followers: 40, SJR: 2.061, h-index: 53)
Evolution, Medicine, and Public Health     Open Access   (Followers: 11)
Family Practice     Hybrid Journal   (Followers: 11, SJR: 1.048, h-index: 77)
Fems Microbiology Ecology     Hybrid Journal   (Followers: 8, SJR: 1.687, h-index: 115)
Fems Microbiology Letters     Hybrid Journal   (Followers: 20, SJR: 1.126, h-index: 118)
Fems Microbiology Reviews     Hybrid Journal   (Followers: 25, SJR: 7.587, h-index: 150)
Fems Yeast Research     Hybrid Journal   (Followers: 13, SJR: 1.213, h-index: 66)
Foreign Policy Analysis     Hybrid Journal   (Followers: 21, SJR: 0.859, h-index: 10)
Forestry: An Intl. J. of Forest Research     Hybrid Journal   (Followers: 16, SJR: 0.903, h-index: 44)
Forum for Modern Language Studies     Hybrid Journal   (Followers: 6, SJR: 0.108, h-index: 6)
French History     Hybrid Journal   (Followers: 31, SJR: 0.123, h-index: 10)
French Studies     Hybrid Journal   (Followers: 19, SJR: 0.119, h-index: 7)
French Studies Bulletin     Hybrid Journal   (Followers: 10, SJR: 0.102, h-index: 3)
Gastroenterology Report     Open Access   (Followers: 2)
Genome Biology and Evolution     Open Access   (Followers: 9, SJR: 3.22, h-index: 39)
Geophysical J. Intl.     Hybrid Journal   (Followers: 34, SJR: 1.839, h-index: 119)
German History     Hybrid Journal   (Followers: 25, SJR: 0.437, h-index: 13)
GigaScience     Open Access   (Followers: 3)
Global Summitry     Hybrid Journal  
Glycobiology     Hybrid Journal   (Followers: 14, SJR: 1.692, h-index: 101)
Health and Social Work     Hybrid Journal   (Followers: 48, SJR: 0.505, h-index: 40)
Health Education Research     Hybrid Journal   (Followers: 12, SJR: 0.814, h-index: 80)
Health Policy and Planning     Hybrid Journal   (Followers: 19, SJR: 1.628, h-index: 66)
Health Promotion Intl.     Hybrid Journal   (Followers: 21, SJR: 0.664, h-index: 60)
History Workshop J.     Hybrid Journal   (Followers: 26, SJR: 0.313, h-index: 20)
Holocaust and Genocide Studies     Hybrid Journal   (Followers: 23, SJR: 0.115, h-index: 13)
Human Molecular Genetics     Hybrid Journal   (Followers: 9, SJR: 4.288, h-index: 233)
Human Reproduction     Hybrid Journal   (Followers: 78, SJR: 2.271, h-index: 179)
Human Reproduction Update     Hybrid Journal   (Followers: 18, SJR: 4.678, h-index: 128)
Human Rights Law Review     Hybrid Journal   (Followers: 59, SJR: 0.7, h-index: 21)
ICES J. of Marine Science: J. du Conseil     Hybrid Journal   (Followers: 53, SJR: 1.233, h-index: 88)
ICSID Review     Hybrid Journal   (Followers: 9)
ILAR J.     Hybrid Journal   (Followers: 1, SJR: 1.099, h-index: 51)
IMA J. of Applied Mathematics     Hybrid Journal   (SJR: 0.329, h-index: 26)
IMA J. of Management Mathematics     Hybrid Journal   (Followers: 2, SJR: 0.351, h-index: 20)
IMA J. of Mathematical Control and Information     Hybrid Journal   (Followers: 2, SJR: 0.661, h-index: 28)
IMA J. of Numerical Analysis - advance access     Hybrid Journal   (SJR: 2.032, h-index: 44)
Industrial and Corporate Change     Hybrid Journal   (Followers: 8, SJR: 1.37, h-index: 81)
Industrial Law J.     Hybrid Journal   (Followers: 29, SJR: 0.184, h-index: 15)
Information and Inference     Free  
Integrative and Comparative Biology     Hybrid Journal   (Followers: 8, SJR: 1.911, h-index: 90)
Interacting with Computers     Hybrid Journal   (Followers: 10, SJR: 0.529, h-index: 59)
Interactive CardioVascular and Thoracic Surgery     Hybrid Journal   (Followers: 5, SJR: 0.743, h-index: 35)
Intl. Affairs     Hybrid Journal   (Followers: 51, SJR: 1.264, h-index: 53)
Intl. Data Privacy Law     Hybrid Journal   (Followers: 28)
Intl. Health     Hybrid Journal   (Followers: 5, SJR: 0.835, h-index: 15)
Intl. Immunology     Hybrid Journal   (Followers: 3, SJR: 1.613, h-index: 111)
Intl. J. for Quality in Health Care     Hybrid Journal   (Followers: 32, SJR: 1.593, h-index: 69)
Intl. J. of Constitutional Law     Hybrid Journal   (Followers: 59, SJR: 0.613, h-index: 19)
Intl. J. of Epidemiology     Hybrid Journal   (Followers: 134, SJR: 4.381, h-index: 145)
Intl. J. of Law and Information Technology     Hybrid Journal   (Followers: 4, SJR: 0.247, h-index: 8)
Intl. J. of Law, Policy and the Family     Hybrid Journal   (Followers: 29, SJR: 0.307, h-index: 15)
Intl. J. of Lexicography     Hybrid Journal   (Followers: 8, SJR: 0.404, h-index: 18)
Intl. J. of Low-Carbon Technologies     Open Access   (Followers: 1, SJR: 0.457, h-index: 12)
Intl. J. of Neuropsychopharmacology     Open Access   (Followers: 3, SJR: 1.69, h-index: 79)
Intl. J. of Public Opinion Research     Hybrid Journal   (Followers: 9, SJR: 0.906, h-index: 33)
Intl. J. of Refugee Law     Hybrid Journal   (Followers: 32, SJR: 0.231, h-index: 21)
Intl. J. of Transitional Justice     Hybrid Journal   (Followers: 13, SJR: 0.833, h-index: 12)
Intl. Mathematics Research Notices     Hybrid Journal   (Followers: 1, SJR: 2.052, h-index: 42)
Intl. Political Sociology     Hybrid Journal   (Followers: 31, SJR: 1.339, h-index: 19)
Intl. Relations of the Asia-Pacific     Hybrid Journal   (Followers: 17, SJR: 0.539, h-index: 17)
Intl. Studies Perspectives     Hybrid Journal   (Followers: 7, SJR: 0.998, h-index: 28)
Intl. Studies Quarterly     Hybrid Journal   (Followers: 38, SJR: 2.184, h-index: 68)
Intl. Studies Review     Hybrid Journal   (Followers: 18, SJR: 0.783, h-index: 38)
ISLE: Interdisciplinary Studies in Literature and Environment     Hybrid Journal   (Followers: 1, SJR: 0.155, h-index: 4)
ITNOW     Hybrid Journal   (Followers: 2, SJR: 0.102, h-index: 4)
J. of African Economies     Hybrid Journal   (Followers: 15, SJR: 0.647, h-index: 30)
J. of American History     Hybrid Journal   (Followers: 40, SJR: 0.286, h-index: 34)
J. of Analytical Toxicology     Hybrid Journal   (Followers: 13, SJR: 1.038, h-index: 60)
J. of Antimicrobial Chemotherapy     Hybrid Journal   (Followers: 12, SJR: 2.157, h-index: 149)
J. of Antitrust Enforcement     Hybrid Journal   (Followers: 1)
J. of Applied Poultry Research     Hybrid Journal   (Followers: 3, SJR: 0.563, h-index: 43)
J. of Biochemistry     Hybrid Journal   (Followers: 43, SJR: 1.341, h-index: 96)
J. of Chromatographic Science     Hybrid Journal   (Followers: 16, SJR: 0.448, h-index: 42)
J. of Church and State     Hybrid Journal   (Followers: 11, SJR: 0.167, h-index: 11)
J. of Competition Law and Economics     Hybrid Journal   (Followers: 34, SJR: 0.442, h-index: 16)
J. of Complex Networks     Hybrid Journal   (Followers: 1, SJR: 1.165, h-index: 5)
J. of Conflict and Security Law     Hybrid Journal   (Followers: 12, SJR: 0.196, h-index: 15)
J. of Consumer Research     Full-text available via subscription   (Followers: 41, SJR: 4.896, h-index: 121)
J. of Crohn's and Colitis     Hybrid Journal   (Followers: 9, SJR: 1.543, h-index: 37)
J. of Cybersecurity     Hybrid Journal   (Followers: 3)
J. of Deaf Studies and Deaf Education     Hybrid Journal   (Followers: 9, SJR: 0.69, h-index: 36)
J. of Design History     Hybrid Journal   (Followers: 15, SJR: 0.166, h-index: 14)
J. of Economic Entomology     Full-text available via subscription   (Followers: 6, SJR: 0.894, h-index: 76)
J. of Economic Geography     Hybrid Journal   (Followers: 39, SJR: 2.909, h-index: 69)
J. of Environmental Law     Hybrid Journal   (Followers: 23, SJR: 0.457, h-index: 20)
J. of European Competition Law & Practice     Hybrid Journal   (Followers: 18)
J. of Experimental Botany     Hybrid Journal   (Followers: 14, SJR: 2.798, h-index: 163)
J. of Financial Econometrics     Hybrid Journal   (Followers: 21, SJR: 1.314, h-index: 27)
J. of Global Security Studies     Hybrid Journal   (Followers: 3)
J. of Heredity     Hybrid Journal   (Followers: 4, SJR: 1.024, h-index: 76)
J. of Hindu Studies     Hybrid Journal   (Followers: 7, SJR: 0.186, h-index: 3)
J. of Hip Preservation Surgery     Open Access  
J. of Human Rights Practice     Hybrid Journal   (Followers: 20, SJR: 0.399, h-index: 10)
J. of Infectious Diseases     Hybrid Journal   (Followers: 40, SJR: 4, h-index: 209)
J. of Insect Science     Open Access   (Followers: 9, SJR: 0.388, h-index: 31)

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Journal Cover European Heart Journal - Cardiovascular Imaging
  [SJR: 2.044]   [H-I: 58]   [9 followers]  Follow
    
   Hybrid Journal Hybrid journal (It can contain Open Access articles)
   ISSN (Print) 2047-2404 - ISSN (Online) 2047-2412
   Published by Oxford University Press Homepage  [370 journals]
  • Intravascular multimodality imaging: feasibility and role in the
           evaluation of coronary plaque pathology
    • Authors: Michail M; Serruys PW, Stettler R, et al.
      First page: 613
      Abstract: AbstractCoronary artery disease remains the leading cause of death in the developed world. Over recent years, research has been focused on the development of diagnostic intravascular imaging techniques that enable assessment of plaque composition and morphology, and allow identification of vulnerable, high-risk lesions. Nevertheless recent studies of coronary atherosclerosis have shown that invasive modalities have a limited accuracy in detecting lesions that will progress and cause events, whilst histology-based studies also highlighted the limitations of invasive imaging in assessing plaque characteristics. To overcome these drawbacks, multimodality imaging has been proposed. Although it is apparent that coronary imaging with two or three imaging modalities is time consuming and is associated with a risk of complications, evidence from small clinical studies demonstrated that it provides incremental information about plaque pathology and biology and underscored the need to develop dual-probe hybrid imaging catheters that would enable complete and comprehensive assessment of plaque morphology. This paper reviews the current clinical evidence that supports the use of multimodality intravascular imaging in the study of atherosclerosis, summarizes the key findings of the first invasive imaging studies that utilize hybrid dual-probe catheters, and discusses the limitations of combined intravascular imaging that restrict its broad application in both the clinical and research arena.
      PubDate: 2017-02-17
      DOI: 10.1093/ehjci/jew330
       
  • EuroEcho-Imaging 2016: highlights
    • Authors: Magne J; Popescu BA, Bucciarelli-Ducci C, et al.
      First page: 621
      Abstract: AbstractThe annual meeting of the European Association of Cardiovascular Imaging, EuroEcho-Imaging, was held in Leipzig, Germany, in December 2016. In the present paper, we present a summary of the ‘Highlights’ session.
      PubDate: 2017-04-11
      DOI: 10.1093/ehjci/jex063
       
  • Importance of combined left atrial size and estimated pulmonary pressure
           for clinical outcome in patients presenting with heart failure with
           preserved ejection fraction
    • Authors: Donal E; Lund LH, Oger E, et al.
      First page: 629
      Abstract: AimsHeart failure with preserved ejection fraction (HFpEF) is a complex syndrome with various phenotypes and outcomes. The prognostic relevance of echocardiography and the E/e′ ratio has previously been reported. We sought to study in addition, the value of estimated pulmonary pressure and left atrial size for diagnosing and determining a prognosis for HFpEF-patients in a prospective multi-centric cohort.Methods and resultsPatients with an acute-HF event accompanied with NT-proBNP >300 pg/mL (BNP >100 pg/mL) and LVEF >45% were included (n = 237) and clinically reassessed using echo-Doppler after 4–8 weeks of HF treatment as part of the prospective KaRen HFpEF study. A core-centre performed the echocardiographic analyses. A combined primary endpoint of either HF hospitalizations and mortality over a span of 18-month, or simply mortality (secondary endpoint) were used. The mean LVEF was 62 ± 7%, E/e’:12.9 ± 6.0, left atrial volume index (LAVI): 48.1 ± 15.9 ml/m2, TR: 2.9 ± 0.9 m/s. Patients with both LAVI > 40 ml/m2 and TR > 3.1 m/s had a significantly greater risk of death or heart failure related hospitalization than others (P = 0.014 after adjustment).ConclusionThe combination of enlarged LA and elevated estimated pulmonary pressure has a strong prognostic impact in patients suffering from HFpEF. Our results indicate that such patients constitute a risk group in HFpEF which requires dedicated medical attention.ClinicalTrials.govNCT00774709
      PubDate: 2017-03-04
      DOI: 10.1093/ehjci/jex005
       
  • Phenotyping heart failure with preserved ejection fraction by
           echocardiography: a light in the tunnel?
    • Authors: Ikonomidis I; Vlastos D, Parissis J.
      First page: 636
      Abstract: Heart failure with preserved ejection fraction (HFpEF) is a growing cardiac disease associated with significant morbidity and an increased risk of in-hospital, short-term, and long-term mortality.1,2
      PubDate: 2017-03-05
      DOI: 10.1093/ehjci/jex025
       
  • Paclitaxel crystals on the surface of a bioresorbable vascular scaffold
           visualized by optical coherence tomography after drug-eluting balloon
           angioplasty
    • Authors: López-Benito M; Pérez de Prado A, Cuellas C, et al.
      First page: 638
      Abstract: A 79-year-old male with history of coronary artery disease with percutaneous revascularization of medium left anterior descending artery with a bare metal stent 2.5 × 23 mm presented with unstable angina. A significant in-stent restenosis (ISR) was observed (Panel A), and treated by means of an in-stent bioresorbable vascular scaffold (BVS) (absorb 2.5 × 28 mm) with excellent angiographic result.
      PubDate: 2017-02-27
      DOI: 10.1093/ehjci/jex013
       
  • Severe aortic stenosis with low aortic valve calcification:
           characteristics and outcome following transcatheter aortic valve
           implantation
    • Authors: Abramowitz Y; Jilaihawi H, Pibarot P, et al.
      First page: 639
      Abstract: AimsHigh aortic valve calcification (AVC) assessed with CT may be used to differentiate between severe and non-severe aortic stenosis (AS). Nonetheless, in some cases patients with low calcification are diagnosed with haemodynamically severe AS. The prevalence, mechanism of valve stenosis and implications for transcatheter aortic valve implantation (TAVI) of low AVC severe AS remain unclear. We assessed the clinical and haemodynamic characteristics and the outcome of patients with severe AS and low AVC that undergo TAVI.Methods and resultsNinety-three patients that had low CT aortic valve calcification score (AVCS) were compared to 470 patients with high AVCS. High gradient severe AS was found among 53.8% (50/93) of the patients with low AVCS vs. 86% (404/470) of the patients with high AVCS (P < 0.001). Device success rate was similar between both groups. There were significantly lower rates of postprocedural paravalvular regurgitation (PVR) in the low AVCS group (≥ mild PVR: 12.9% vs. 23.6%; P = 0.03). Overall, there were only two cases (0.4%) of valve embolization in patients with high AVCS and 1 (1.1%) in patients with low AVCS (P = 0.42). Thirty-day mortality and major complications were similar between groups.ConclusionBalloon-expandable TAVI in patients with a mildly calcified aortic valve was not associated with increased risk of valve embolization or mortality. We demonstrated high device success and lower rates of PVR for these patients. These findings suggest that in patients with evidence of haemodynamically severe AS at echocardiography, the presence of low ACVS at CT should not preclude the consideration of TAVI.
      PubDate: 2017-03-27
      DOI: 10.1093/ehjci/jex006
       
  • Relation between calcium burden, echocardiographic stent frame
           eccentricity and paravalvular leakage after corevalve transcatheter aortic
           valve implantation
    • Authors: Di Martino LM; Soliman OI, van Gils L, et al.
      First page: 648
      Abstract: AimsParavalvular aortic leakage (PVL) after transcatheter aortic valve implantation (TAVI) is a complication with potentially severe consequences. The relation between native aortic root calcium burden, stent frame eccentricity and PVL was not studied before.Methods and resultsTwo-hundred-and-twenty-three consecutive patients with severe aortic stenosis who underwent TAVI with a Medtronic CoreValve System© and who had available pre-discharge transthoracic echocardiography were studied. Echocardiographic stent inflow frame eccentricity was defined as major–minor diameter in a short-axis view >2 mm. PVL was scored according to the updated Valve Academic Research Consortium (VARC-2) recommendations. In a subgroup of 162 (73%) patients, the calcium Agatston score was available. Stent frame eccentricity was seen in 77 (35%) of patients. The correlation between the Agatston score and stent frame eccentricity was significant (ρ = 0.241, P = 0.003). Paravalvular leakage was absent in 91 cases (41%), mild in 67 (30%), moderate in 51 (23%), and severe in 14 (6%) cases. The correlation between stent frame eccentricity and PVL severity was significant (ρ = 0.525, P < 0.0001). There was a relation between particular eccentric stent frame shapes and the site of PVL.ConclusionCalcification of the aortic annulus is associated with a subsequent eccentric shape of the CoreValve prosthesis. This eccentric shape results in more PVL, with the localization of PVL related to the shape of stent frame eccentricity.
      PubDate: 2017-03-27
      DOI: 10.1093/ehjci/jex009
       
  • Aortic root calcium burden and post-transcatheter aortic valve
           implantation paravalvular leak: Can’t Live Without It, Can’t Live With
           It
    • Authors: Qian Z; Lancellotti P, Vannan MA.
      First page: 654
      Abstract: Transcatheter aortic valve implantation (TAVI) is an established therapeutic option for symptomatic patients with severe aortic stenosis (AS) who are at high risk for surgical aortic valve replacement (SAVR). Evidences from recent trials showed that it may be appropriate to expand the indication of TAVI to patients with intermediate or even low risk of surgery.1 Compared to SAVR, TAVI is non-inferior in terms of death or disabling stroke rate.2 However, because of the sutureless nature of TAVI, despite the fast evolving TAVI technology, many transcatheter heart valves suffer from a greater rate and severity of post-TAVI paravalvular leak (PVL) than the surgical sewing valves.2,3 Moderate to severe PVL after TAVI has been shown to be an independent risk factor for increased short- and long-term mortality.4,5 Given the emerging expansion of the TAVI indication to the lower risk population, prevention of post-TAVI PVL becomes even more critical.
      PubDate: 2017-03-27
      DOI: 10.1093/ehjci/jex032
       
  • A case of mitral annuloplasty band dehiscence
    • Authors: Lin L; Sherrah A, Vallely M, et al.
      First page: 662
      Abstract: A 66-year-old man was admitted to hospital for a planned percutaneous transcatheter mitral valve repair (Mitraclip) for severe mitral regurgitation after a previous mitral repair with an annuloplasty ring. He presented with increasing exertional dyspnoea and had clinical left heart failure on admission. His history was of ischaemic heart disease with stenting of the circumflex artery and posterolateral branch in 2001 and a vein graft to the first diagonal at the time of mitral valve repair for severe ischaemic mitral regurgitation in 2006. He had an implanted defibrillator.
      PubDate: 2017-02-15
      DOI: 10.1093/ehjci/jex016
       
  • Spontaneous mitral valve anterior leaflet perforation
    • Authors: Al-Atia B; Verbrugghe P, Voigt J.
      First page: 680
      Abstract: A 22-year-old man without past medical history had gradually developed exercise intolerance and exertional dyspnoea. Physical examination revealed a 4/6 apical systolic murmur radiating to the axilla. Electrocardiogram was normal. Transthoracic echocardiography showed a bicuspid aortic valve with severe eccentric regurgitation (AR) pointing at the anterior mitral leaflet (AML) and a severe mitral regurgitation (MR) apparently originating from the AML. Three dimensional transoesophageal echocardiography confirmed these findings (PanelsA  and B, respectively) and revealed a round 8 mm hole in the AML (yellow arrows) without any further structural abnormalities of the valve. Coronary computed tomography was normal. The patient underwent surgical reconstruction of the aortic and the mitral valve (Panel D). Microbiological culture, pan-bacterial polymerase chain reaction, and histopathological analysis were negative.
      PubDate: 2017-02-15
      DOI: 10.1093/ehjci/jex018
       
  • Erratum to: European Heart Journal – Cardiovascular Imaging Top
           Reviewers 2016
    • First page: 696
      Abstract: [Eur Heart J Cardiovasc Imaging 2017;18:118]
      PubDate: 2017-04-03
      DOI: 10.1093/ehjci/jex042
       
  • Erratum to: Improved 5-year prediction of all-cause mortality by coronary
           CT angiography applying the CONFIRM score
    • First page: 706
      Abstract: [Eur Heart J Cardiovasc Imaging 2017;18:286–93]
      PubDate: 2017-04-10
      DOI: 10.1093/ehjci/jex041
       
  • Isolated left subclavian artery arising from the main pulmonary artery
    • Authors: Ciliberti P; Toscano A, Drago F, et al.
      First page: 716
      Abstract: A 2-week-old male with antenatal diagnosis of ‘pink’ Tetralogy of Fallot was referred to our unit. The transthoracic echocardiography showed a large malalignment ventricular septal defect with overriding aorta, and mild pulmonary valve stenosis in absence of significant sub-valvar right ventricle outflow tract obstruction. A right aortic arch with a non-bifurcating first branch was demonstrated. On the high parasternal short axis view, a vessel originating from the main pulmonary trunk was detected, going leftward and then superiorly. The flow direction within the anomalous structure was towards the pulmonary circulation, representing an additional pulmonary blood flow supply (A; Supplementary data online, Video S1Supplementary data online, Video S1). This was suspected to be the left duct connected to the left subclavian artery (red arrow). A cardiac computed tomography was performed (B; front view on the left, back view on the right), and the abnormal origin of the left subclavian artery (yellow arrow), connected to the main pulmonary artery through a patent left arterial duct, was confirmed. This rare vascular abnormality can be explained using the hypothetical double arch system. (C). According to this system, the arches regressed (dotted lines) between the left common carotid artery and the left subclavian artery, and at the left dorsal aortic arch, distal to the patent left ductus arteriosus. If left untreated, potential closure of the left duct could lead to isolation of the left subclavian artery that typically results in perfusion to the arm through the vertebral artery. The left subclavian artery then can be reimplanted to the aortic arch during surgical correction or left untouched. Our patient underwent a successfully complete repair, with VSD closure, infundibular patch and reimplantation of the left subclavian artery to the left common carotid.
      PubDate: 2017-02-17
      DOI: 10.1093/ehjci/jew337
       
  • Unusual diagnosis of a mass located in the interventricular septum:
           ectopic thyroid (‘Struma cordis’) Struma cordis: an unusual mass in
           the septum
    • Authors: Rassi D; Hotta V, Mota J, et al.
      First page: 717
      Abstract: Journal Subject Codes: Diagnostic testing: [31] Echocardiography, Heart failure: [110] Congestive
      PubDate: 2017-02-23
      DOI: 10.1093/ehjci/jex004
       
  • First experience with real-time 3D anatomical fusion imaging during left
           atrial appendage occluder implantation
    • Authors: Afzal S; Soetemann D, Nijhof N, et al.
      First page: 719
      Abstract: Clinical message
      PubDate: 2017-02-28
      DOI: 10.1093/ehjci/jex030
       
  • Intrapericardial lipoma mimicking atrial tumour
    • Authors: Beck MA; Cianciulli TF, Saccheri MC, et al.
      First page: 721
      Abstract: A 64-year-old patient, attend the consultation for control of his hypertension. A transthoracic echocardiogram demonstrated an echogenic and homogeneous rounded mass with defined edges compressing the left atrium (see Supplementary dataSupplementary data online, Movies S1 and S2). The size of the mass was 60 × 50 mm (A). Colour flow mapping ruled out intracardiac obstruction (see Supplementary dataSupplementary data online, Movie S3). Left ventricular ejection fraction was normal (65%). Multi-detector computed tomography revealed the extracardiac and intrapericardial origin of the mass. The density of the mass was equal to that subcutaneous adipose tissue (Hounsfield measurement −50 HU) compatible with intrapericardial lipoma (B). Lipomas, a tumour composed of mature fat, represents the third most frequent benign cardiac tumour, after myxoma and papillary fibroelastoma. Half of the lipomas are located in the subendocardium and the remaining 25% in the myocardium and 25% in the subepicardium. They occur at any age and with the same frequency in both sexes, as single and encapsulated nodular masses. They are usually underdiagnosed as they usually develop asymptomatically and are generally diagnosed as a finding in routine studies, so their actual incidence is not known. We present a case of an extracardiac mass diagnosed with echocardiography. CT revealed its intrapericardial location and fat content. The tumour was not excised because it did not cause symptoms. This case demonstrates a rare but easy-to-handle differential diagnosis that should be considered when patients present with a cardiac mass.
      PubDate: 2017-03-02
      DOI: 10.1093/ehjci/jex027
       
  • The aureole sign: a rare echocardiographic artefact
    • Authors: Schneider M; Binder T, Maurer G, et al.
      First page: 722
      Abstract: In December 2015, a 72-year-old woman presented to our cardiology department with exertional dyspnoea and chest pain. Significant single-vessel coronary disease of the circumflex artery was diagnosed and treated with percutaneous coronary intervention and drug-eluting stent implantation.
      PubDate: 2017-03-09
      DOI: 10.1093/ehjci/jex003
       
  • Giant left ventricular pseudoaneurysm in a scleroderma patient: evaluation
           by cardiac magnetic resonance
    • Authors: Cosmi D; Olivotti L, Nicolino A, et al.
      First page: 723
      Abstract: A 43-year-old man with scleroderma was referred to our clinic for intermittent chest pain.
      PubDate: 2017-03-21
      DOI: 10.1093/ehjci/jex044
       
  • Large vessel vasculitis in Behçet’s disease
    • Authors: Goliasch G; Hoke M.
      First page: 724
      Abstract: A 29-year-old female refugee from Afghanistan presented with gradual onset of exertional angina. She reported a history of percutaneous coronary intervention of her left anterior descending artery (LAD) at an Iranian clinic 8 months before with implantation of 3 drug eluting stents. Selective coronary angiography revealed an in-stent restenosis of the proximal LAD (Panel A, see Supplementary data online, Video S1Supplementary data online, Video S1), which was treated with a drug-eluting stent (Xience Xpedition 4.0/8mm) with a good angiographic result (see Supplementary data online, Video S2Supplementary data online, Video S2). Transthoracic and subsequent transoesophageal echocardiography exposed an 8 mm echogenic thickening of the posterior wall of the ascending aorta extending to the aortic valve (Panel B, see Supplementary data online, Videos S3 and S4Supplementary data online, Videos S3 and S4) and confirmed by computed tomography (Panel C). Fluorodeoxyglucose (FDG)-positron emission magnet resonance imaging revealed abnormal FDG uptake within the intraaortic wall in proximity to the left main coronary artery (Panel D) as well as the proximal left carotid artery. Our findings complemented by a patient history of oral and genital ulcerations, erythema nodosum, and arthralgia were suggestive for active large-vessel vasculitis in the setting of Behçet’s disease. Thus, immunsupressive treatment with prednisolone and cyclophosphamide was initiated and the patient was discharged in good condition.
      PubDate: 2017-03-27
      DOI: 10.1093/ehjci/jex045
       
  • Utility of near-infrared spectroscopy for detection of thin-cap
           neoatherosclerosis
    • Authors: Roleder T; Karimi Galougahi K, Chin C, et al.
      Abstract: AimsNear-infrared spectroscopy (NIRS) has been employed to assess the composition of the atherosclerotic plaques in native coronary arteries. However, little is known about the detection of neoatherosclerosis by NIRS in in-stent restenosis (ISR). The aim of the study was to assess the relationship between the distribution of lipid determined by NIRS and morphology of ISR on optical coherence tomography (OCT).Methods and resultsWe performed both NIRS and OCT in 39 drug-eluting stents with ISR. Values of lipid-core burden index (LCBI) derived by NIRS were compared with the OCT-derived thickness of the fibrous cap covering neoatherosclerotic lesions. A total of 22 (49%) in-stent neointimas were identified as lipid rich by both NIRS and OCT. There was good agreement between OCT and NIRS in identifying lipid within in-stent neointima (kappa = 0.60, 95% CI: 0.34–0.86). OCT identified thin-cap neoatheromas (TCNA) (<65 µm) in 12 stents (23%). The minimal cap thickness of in-stent neoatherosclerotic plaque measured by OCT correlated with the maxLCBI4mm (maximal LCBI per 4 mm) within the stent (r = −0.77, P< 0.01). Moreover, maxLCBI4mm was able to accurately predict TCNA with a cut-off value of >144.ConclusionNIRS correlates with OCT identification of lipids in stented vessels and is able to predict the presence of thin fibrous cap neoatheroma.
      PubDate: 2016-09-27
       
  • Prevalence of unrecognized myocardial infarction in a low–intermediate
           risk asymptomatic cohort and its relation to systemic atherosclerosis
    • Authors: Weir-McCall JR; Fitzgerald K, Papagiorcopulo CJ, et al.
      Abstract: AimsUnrecognized myocardial infarctions (UMIs) have been described in 19–30% of the general population using late gadolinium enhancement (LGE) on cardiac magnetic resonance. However, these studies have focused on an unselected cohort including those with known cardiovascular disease (CVD). The aim of the current study was to ascertain the prevalence of UMIs in a non-high-risk population using magnetic resonance imaging (MRI).Methods and resultsA total of 5000 volunteers aged >40 years with no history of CVD and a 10-year risk of CVD of <20%, as assessed by the ATP-III risk score, were recruited to the Tayside Screening for Cardiac Events study. Those with a B-type natriuretic peptide (BNP) level greater than their gender-specific median were invited for a whole-body MR angiogram and cardiac MR including LGE assessment. LGE was classed as absent, UMI, or non-specific. A total of 1529 volunteers completed the imaging study; of these, 53 (3.6%) were excluded because of either missing data or inadequate LGE image quality. Ten of the remaining 1476 (0.67%) displayed LGE. Of these, three (0.2%) were consistent with UMI, whereas seven were non-specific occurring in the mid-myocardium (n = 4), epicardium (n = 1), or right ventricular insertion points (n = 2). Those with UMI had a significantly higher BNP [median 116 (range 31–133) vs. 22.6 (5–175) pg/mL, P = 0.015], lower ejection fraction [54.6 (36–62) vs. 68.9 (38–89)%, P = 0.007], and larger end-systolic volume [36.3 (27–61) vs. 21.7 (5–65) mL/m2, P = 0.014]. Those with non-specific LGE had lower diastolic blood pressure [68 (54–70) vs. 72 (46–98) mmHg, P = 0.013] but no differences in their cardiac function.ConclusionDespite previous reports describing high prevalence of UMI in older populations, in a predominantly middle-aged cohort, those who are of intermediate or low cardiovascular risk have a very low risk of having an unrecognized myocardial infarct.
      PubDate: 2016-08-22
       
  • Non-invasive assessment of the haemodynamic significance of coronary
           stenosis using fusion of cardiac computed tomography and 3D
           echocardiography
    • Authors: Maffessanti F; Patel AR, Patel MB, et al.
      Abstract: AimsAbnormal computed tomography coronary angiography (CTCA) often leads to stress testing to determine haemodynamic significance of stenosis. We hypothesized that instead, this could be achieved by fusion imaging of the coronary anatomy with 3D echocardiography (3DE)-derived resting myocardial deformation.Methods and resultsWe developed fusion software that creates combined 3D displays of the coronary arteries with colour maps of longitudinal strain and tested it in 28 patients with chest pain, referred for CTCA (256 Philips scanner) who underwent 3DE (Philips iE33) and regadenoson stress CT. To obtain a reference for stenosis significance, coronaries were also fused with colour maps of stress myocardial perfusion. 3D displays were used to detect stress perfusion defect (SPD) and/or resting strain abnormality (RSA) in each territory. CTCA showed 56 normal arteries, stenosis <50% in 17, and >50% in 8 arteries. Of the 81 coronary territories, SPDs were noted in 20 and RSAs in 29. Of the 59 arteries with no stenosis >50% and no SPDs, considered as normal, 12 (20%) had RSAs. Conversely, with stenosis >50% and SPDs (haemodynamically significant), RSAs were considerably more frequent (5/6 = 83%). Overall, resting strain and stress perfusion findings were concordant in 64/81 arteries (79% agreement).ConclusionsFusion of CTCA and 3DE-derived data allows direct visualization of each coronary artery and strain in its territory. In this feasibility study, resting strain showed good agreement with stress perfusion, indicating that it may be potentially used to assess haemodynamic impact of coronary stenosis, as an alternative to stress testing that entails additional radiation exposure.
      PubDate: 2016-07-26
       
  • Regular endurance training in adolescents impacts atrial and ventricular
           size and function
    • Authors: Rundqvist L; Engvall J, Faresjö M, et al.
      Abstract: AimsThe aims of the study were to explore the effects of long-term endurance exercise on atrial and ventricular size and function in adolescents and to examine whether these changes are related to maximal oxygen uptake (VO2max).Methods and resultsTwenty-seven long-term endurance-trained adolescents aged 13–19 years were individually matched by age and gender with 27 controls. All participants, 22 girls and 32 boys, underwent an echocardiographic examination at rest, including standard and colour tissue Doppler investigation. VO2max was assessed during treadmill exercise. All heart dimensions indexed for body size were larger in the physically active group compared with controls: left ventricular end-diastolic volume 60 vs. 50 mL/m2 (P <0.001), left atrial volume 27 vs. 19 mL/m2 (P < 0.001), and right ventricular (RV) and right atrial area 15 vs. 13 and 9 vs. 7 cm2/m2, respectively (P <0.001 for both). There were strong associations between the size of the cardiac chambers and VO2max. Further, we found improved systolic function in the active group compared with controls: left ventricular ejection fraction 61 vs. 59% (P= 0.036), tricuspid annular plane systolic excursion 12 vs. 10 mm/m2 (P= 0.008), and RV early peak systolic velocity s′ 11 vs. 10 cm/s (P = 0.031).ConclusionCardiac remodelling to long-term endurance exercise in adolescents is manifested by an increase in atrial as well as ventricular dimensions. The physically active group also demonstrated functional remodelling with an increase in TAPSE and systolic RV wall velocity. These findings have practical implications when assessing cardiac enlargement and function in physically active youngsters.
      PubDate: 2016-07-11
       
  • Impact of high-intensity endurance exercise on regional left and right
           ventricular myocardial mechanics
    • Authors: Stewart GM; Chan J, Yamada A, et al.
      Abstract: AimsStrenuous endurance exercise acutely increases myocardial wall stress and evokes transient functional cardiac perturbations. However, it is unclear whether exercise-induced functional cardiac disturbances are ubiquitous throughout the myocardium or are segment specific. The aim of this study was to examine the influence of high-intensity endurance exercise on global and segmental left (LV) and right (RV) ventricular tissue deformation (strain).Methods and resultsEchocardiography was used to measure strain in 23 active men (age: 28 ± 2 years; VO2 peak: 4.5 ± 0.7 L min−1) at rest and during a standardized low-intensity exercise challenge, before and after a 90-min high-intensity endurance cycling intervention. Following the cycling intervention, LV and RV global strain decreased at rest (LV: −18.4 ± 0.4% vs. −17.7 ± 0.4%, P < 0.05; RV: −27.6 ± 0.7% vs. −26.4 ± 0.6%, P < 0.05) and by a greater extent during the low-intensity exercise challenge (LV: −21.3 ± 0.4% vs. −19.2 ± 0.5%, P < 0.01; RV: −28.4 ± 0.8% vs. −23.5 ± 0.9%, P < 0.01). Reductions in LV strain were unique to regions of RV attachment (e.g. LV septum: −24.4 ± 0.5% vs. −21.4 ± 0.6%, P < 0.01) with lateral (−18.9 ± 0.4% vs. −18.4 ± 0.5%) and posterior segments (−19.5 ± 0.4% vs. −18.8 ± 0.7%) unaffected. Similarly, augmentation of strain from rest to exercise was abolished in the RV free wall (−1.1 ± 1.0% vs. 2.9 ± 1.2%, P < 0.01), reduced in the septum (−4.6 ± 0.4% vs. −2.4 ± 0.5%, P < 0.01), and unchanged in the lateral (−1.2 ± 0.6% vs. −0.9 ± 0.6%) and posterior walls (−1.7 ± 0.6% vs. −1.3 ± 0.7%).ConclusionChanges in ventricular strain following high-intensity exercise are more profound in the right ventricle than in the left ventricle. Reductions in LV strain were unique to the septal myocardium and may reflect ventricular interactions secondary to exercise-induced RV dysfunction.
      PubDate: 2016-07-02
       
  • A simplified and reproducible method to size the mitral annulus:
           implications for transcatheter mitral valve replacement
    • Authors: Abdelghani M; Spitzer E, Soliman OI, et al.
      Abstract: AimsTranscatheter mitral valve replacement (TMVR) provides definitive valve replacement through a minimally invasive procedure. In the setting of TMVR, it remains unclear how relevant the differences between different mitral annular (MA) diameters are. We sought to define a simplified and reproducible method to describe the MA size.Methods and resultsUsing cardiac computed tomography angiography (CTA) studies of 47 patients, 3D MA perimeter (P3D) was annotated. The aorto-mitral continuity was excluded from MA contour either by manual annotation (yielding a saddle-shape model) or by simple truncation at the medial and lateral trigones (yielding a D-shape model). The method of the least squares was used to generate the projected MA area (Aproj) and perimeter (Pproj). Intercommissural (IC) and septolateral (SL) diameters, Dmean = (IC diameter + SL diameter)/2, area-derived diameter (DArea = 2 x √(A/π)) and perimeter-derived diameter (DPerimeter = P/π) were measured. MA eccentricity, height, and calcification (MAC) were assessed. Thirty studies were re-read by the same and by another observer to test intra- and inter-observer reproducibility. Patients (age, 75 ± 12 years, 66% males) had a wide range of mitral regurgitation severity (none-trace in 8%, mild in 55%, moderate–severe in 37%), MA size (area: 5–16 cm2), eccentricity (−8–52%), and height (3–11 mm). MAC was seen in 11 cases, in whom MAC arc occupied 26 ± 20% of the MA circumference. DArea (36.0 ± 4.0 mm) and DPerimeter (37.1 ± 3.8 mm) correlated strongly (R2 = 0.97) and were not significantly different (P = 0.15). The IC (39.3 ± 4.6 mm) and the SL (31.4 ± 4.5 mm) diameters were significantly different from DArea (P < 0.001) while Dmean (35.4 ± 4.0 mm) was not (P = 0.5). The correlation of DArea was stronger with Dmean (R2 = 0.96) than with IC and SL diameters (R2 = 0.69 and 0.76, respectively). The average difference between DArea and Dmean was +0.6 mm and the 95% limits of agreement were 2.1 and −0.9 mm. Similar results were found when the D-shape model was applied. All MA diameters showed good reproducibility with high intraclass correlation coefficient (0.93–0.98), small average bias (0.37–1.1 mm), and low coefficient of variation (3–7%) for intra- and inter-observer comparisons. Reproducibility of DArea was lower in patients with MAC.ConclusionMA sizing by CTA is readily feasible and reproducible. Dmean is a simple index that can be used to infer the effective MA size.
      PubDate: 2016-06-26
       
  • Intervendor consistency and reproducibility of left ventricular 2D global
           and regional strain with two different high-end ultrasound systems
    • Authors: Shiino K; Yamada A, Ischenko M, et al.
      Abstract: AimsWe aimed to assess intervendor agreement of global (GLS) and regional longitudinal strain by vendor-specific software after EACVI/ASE Industry Task Force Standardization Initiatives for Deformation Imaging.Methods and resultsFifty-five patients underwent prospective dataset acquisitions on the same day by the same operator using two commercially available cardiac ultrasound systems (GE Vivid E9 and Philips iE33). GLS and regional peak longitudinal strain were analyzed offline using corresponding vendor-specific software (EchoPAC BT13 and QLAB version 10.3). Absolute mean GLS measurements were similar between the two vendors (GE −17.5 ± 5.2% vs. Philips −18.9 ± 5.1%, P = 0.15). There was excellent intervendor correlation of GLS by the same observer [r = 0.94, P < 0.0001; bias −1.3%, 95% CI limits of agreement (LOA) −4.8 to 2.2%). Intervendor comparison for regional longitudinal strain by coronary artery territories distribution were: LAD: r = 0.85, P < 0.0001; bias 0.5%, LOA −5.3 to 6.4%; RCA: r = 0.88, P < 0.0001; bias −2.4%, LOA −8.6 to 3.7%; LCX: r = 0.76, P < 0.0001; bias −5.3%, LOA −10.6 to 2.0%. Intervendor comparison for regional longitudinal strain by LV levels were: basal: r = 0.86, P < 0.0001; bias −3.6%, LOA −9.9 to 2.0%; mid: r = 0.90, P < 0.0001; bias −2.6%, LOA −7.8 to 2.6%; apical: r = 0.74; P < 0.0001; bias −1.3%, LOA −9.4 to 6.8%.ConclusionsIntervendor agreement in GLS and regional strain measurements have significantly improved after the EACVI/ASE Task Force Strain Standardization Initiatives. However, significant wide LOA still exist, especially for regional strain measurements, which remains relevant when considering vendor-specific software for serial measurements.
      PubDate: 2016-06-21
       
 
 
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