Publisher: Universitas Airlangga   (Total: 51 journals)   [Sort by number of followers]

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Amerta Nutrition     Open Access  
Berkala Akuntansi dan Keuangan Indonesia     Open Access  
Berkala Ilmu Kesehatan Kulit dan Kelamin / Periodical of Dermatology and Venereology     Open Access  
Biomolecular and Health Science J.     Open Access   (Followers: 1)
Critical, Medical and Surgical Nursing J.     Open Access  
Dental J. (Majalah Kedokteran Gigi)     Open Access   (Followers: 2)
Etnolingual     Open Access   (Followers: 2)
Folia Medica Indonesiana     Open Access  
Fundamental and Management Nursing J.     Open Access  
Global & Strategis     Open Access   (Followers: 2)
Indonesian J. of Occupational Safety and Health     Open Access   (Followers: 3)
Indonesian J. of Public Health     Open Access   (Followers: 2)
Indonesian J. of Tropical and Infectious Disease     Open Access  
INSAN Jurnal Psikologi dan Kesehatan Mental     Open Access  
Intl. J. of Applied Business     Open Access   (Followers: 1)
J. of Developing Economies     Open Access   (Followers: 5)
J. of Halal Product and Research     Open Access   (Followers: 1)
J. of Information Systems Engineering and Business Intelligence     Open Access   (Followers: 1)
J. of Parasite Science     Open Access   (Followers: 2)
J. of Public Health Research and Community Health Development     Open Access  
J. of Stem Cell Research and Tissue Engineering     Open Access  
J. of Vocational Health Studies     Open Access   (Followers: 1)
Jurist-Diction     Open Access  
Jurnal Administrasi Kesehatan Indonesia     Open Access  
Jurnal Berkala Epidemiologi     Open Access   (Followers: 1)
Jurnal Biometrika dan Kependudukan     Open Access   (Followers: 1)
Jurnal Biosains Pascasarjana     Open Access  
Jurnal Ekonomi dan Bisnis Islam (J. of Islamic Economics and Business)     Open Access  
Jurnal Ekonomi Syariah Teori dan Terapan     Open Access  
Jurnal Farmasi dan Ilmu Kefarmasian Indonesia     Open Access  
Jurnal Hubungan Internasional     Open Access  
Jurnal Ilmiah Perikanan dan Kelautan / Scientific J. of Fisheries and Marine     Open Access  
Jurnal Ilmu Ekonomi Terapan     Open Access  
Jurnal Kesehatan Lingkungan     Open Access  
Jurnal Kimia Riset     Open Access  
Jurnal Lakon     Open Access  
Jurnal Manajemen Teori dan Terapan | J. of Theory and Applied Management     Open Access  
Jurnal Medik Veteriner     Open Access  
Jurnal Ners     Open Access  
Jurnal PROMKES : Jurnal Promosi Kesehatan dan Pendidikan Kesehatan Indonesia (The Indonesian J. of Health Promotion and Health Education)     Open Access  
Jurnal Respirasi     Open Access  
Juxta : Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga     Open Access  
Majalah Obstetri & Ginekologi     Open Access  
Masyarakat, Kebudayaan dan Politik     Open Access   (Followers: 1)
Media Gizi Indonesia     Open Access   (Followers: 1)
Media Iuris     Open Access  
Mozaik Humaniora     Open Access  
Notaire     Open Access  
Pediomaternal Nursing J.     Open Access  
Record and Library J.     Open Access   (Followers: 8)
Yuridika     Open Access   (Followers: 1)
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Folia Medica Indonesiana
Number of Followers: 0  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2355-8393 - ISSN (Online) 2599-056X
Published by Universitas Airlangga Homepage  [51 journals]
  • Quantity of Antibiotic Use and Resistance Pattern of Gut Normal Flora
           Escherichia coli at Intensive Care Unit and Tropic Infection Ward, Dr
           Soetomo Hospital, Surabaya, Indonesia

    • Authors: Mohammad Akbaruddin Sholeh, K Kuntaman, Usman Hadi
      Pages: 159 - 164
      Abstract: This study aimed to analyze the relationship of the quantity of antibiotic use with the pattern of resistance of gut normal flora Escherichia coli among patients in Intensive Care Unit (ICU) and Tropic Infection Ward, Dr. Soetomo Hospital, Surabaya. This study was cross-sectional design with 64 samples (32 the ICU and 32 in Tropic Infection Ward). The total sample were collected for three Months. Identification of intestinal microflora was done with McConkey differential selective medium, followed by IMViC biochemical test, and sensitivity test by antibiotic disc diffusion method. Data were analyzed with Chi square test and Fisher's Exact test. There was no significant difference (p=0.441) in the quantity of antibiotic use between ICU and Tropic Infection Ward. There was no significant difference (p>0.05) in normal intestinal flora Escherichia coli resistance pattern between Tropic Infection Ward and ICU against 12 types of antibiotics. The highest percentage of intestinal flora Escherichia coli  resistance at the ICU was ceftriaxone as many as 18 (56.3%) and at Tropic Infection Ward on ciprofloxacin and levofloxacin 20 (62.5%). The other study in Primary Health center, showed that the resistance rates of both wards were significantly different as compared to intestinal flora of patients in primary health center (p <0.001), in which the use of antibiotics in primary health center was also lower (1.6 DDD). There was no significant difference (p>0.05) The pattern of bacterial resistance between patient with and without antibiotic use at Tropic Infection Ward and ICU. The quantity of antibiotic use was not significantly different against resistnt gut flora between patients in ICU and Tropic Infection ward. The pattern of bacterial resistance between patient with and without antibiotic use was also not significantly different.
      PubDate: 2020-09-23
      DOI: 10.20473/fmi.v56i3.22161
      Issue No: Vol. 56, No. 3 (2020)
  • Effect of Simvastatin in Serum Interleukin-6 Level in Patients with Acute
           Ischemic Stroke

    • Authors: Maria Lettisia Meo, Abdulloh Machin, Didik Hasmono
      Pages: 165 - 173
      Abstract: Acute ischemic stroke is the leading cause of death and causing permanent disability in adults worldwide. In acute ischemic stroke, IL-6 levels positively correlated to more severe neurological deficits, more extensive brain damage and worse prognoses. The use of statin was associated with milder initial stroke severity, better functional outcome and lower mortality. This clinically randomized controlled trial study was aimed to analyze the serum levels of IL 6 in acute ischemic stroke patients who treated with Simvastatin 20 mg compare to placebo. Samples were taken using consecutive sampling method from hospitalized acute ischemic stroke patients in Neurology Department of Dr. Soetomo Teaching Hospital Surabaya and Airlangga University Hospital Surabaya from August to November 2017. Total of 44 patients met the inclusion criteria, consisting of 22 patients in treatment group and 22 patients in control group. There were no significant difference in the characteristic of the patients in both groups (p>0.05). Averages of serum IL-6 in the control and the treatment group are 38.594±74.313 and 17.760±25.253 (p=0,438) while averages of serum IL-6 post in the control group and the treatment are 46.586±103.484 and 15.275±17.183 (p=0,589). There were no significant level escalation in pre and post of control group (p=0.205) and also no significant level reduction in pre and post of treatment group (p=0.411), while the average difference in the control group  (-7.992 ± 78.912 pg/ml) and in the treatment group (2.485 ± 23.738 pg/ml).
      PubDate: 2020-09-23
      DOI: 10.20473/fmi.v56i3.22162
      Issue No: Vol. 56, No. 3 (2020)
  • Influence of Administering Watermelon Rind Water Extract (Citrullus
           vulgaris Schard) on Glucose Level of Male White Rats (Rattus norvegicus)
           Induced with Streptozotosin

    • Authors: Hasyim As’ari, Sugiyanta Sugiyanta
      Pages: 174 - 177
      Abstract: Watermelon rind water extract contain of citrulline. Citrulline is a precursor of generating Nitric Oxide (NO). NO possibly reduced the level of blood glucose in streptozotosin-induced diabetic rats. This study was a laboratory experimental study completely randomized design. A number of 30 male albino Wistar rats weighting 100 – 200 gr were devided into six groups (N=5), with group 1 served as normal control group. The other groups were given streptozotosin to induced diabetes mellitus. The rats in control diabetic group were given CMC 0,5%, the others were given watermelon rind extracs for 8 days with different doses for each group. The results showed that serum glucose levels in posttest control group was significantly different, from that group of the watermelon rind extract 250 mg/kg bw/day (p=0.000), groups of watermelon rind extract 500 mg/kgbw/day (p=0,000) and groups of watermelon rind extract 1000 mg/kg bw/day (p=0.000). The level of triglyceride in postest control was significantly different from that group of the watermelon rind extract 250 mg/kg bw/day (p=0.000), groups of watermelon rind extract 500 mg/kgbw/day (p=0.000) and groups of watermelon rind extract 1000 mg/kgbw/day (p=0.000). The conclusion, the watermelon rind water extrac can be used to reduced glucose serum level (250, 500, 1000 mg/kg bw) with the optimal dose was 500 mg /kg bw/day with the optimal dose was 1000 mg/kg bw/day. 
      PubDate: 2020-09-23
      DOI: 10.20473/fmi.v56i3.22163
      Issue No: Vol. 56, No. 3 (2020)
  • Correlations Between Staging and Chemotheraphy Response with Testicular
           Carcinoma Non-Seminoma at Dr. Soetomo Hospital, Surabaya, Indonesia

    • Authors: Achmad Nugroho, Johan Renaldo, Wahjoe Djatisoesanto
      Pages: 178 - 185
      Abstract: The purpose of this study was to describe patients’ characteristics, correlation between staging non-seminoma cancer and chemotherapy response. Data on age, location of tumor, staging, serum levels of the tumor marker post operative, adjuvant therapy, chemotherapy side effects, and response of patient to chemotherapy were gained from medical records in Soetomo Hospital Surabaya from January 2012 to December 2015, and analyzed with SPSS. Correlation between staging and chemotherapy response, correlation primary tumor staging (pT) and Metastasis (M), correlation regional lymph nodes staging (N) and metastasis (M), correlation serum tumor marker and chemotherapy response was proccessed by Spearman correlation test. There were no significant correlation between pT staging and M and no significant correlation between N and M staging. Based on tumor markers (S), mostly patients were S2. There were no significant correlation between the response to chemotherapy and serum tumor marker levels. In category of staging group, the most are 14 patients stage III. BEP was the most adjuvant Chemotherapy. Nausea and vomiting were The most complained during chemotherapy. Anemia were the most hematologic side effects of chemotherapy. There are no significant correlation between the staging of non-seminoma and the response to chemotherapy. Conclusion: Non seminoma mostly happened in young males. Non-seminoma responses to chemotherapy. Patients in early stage would give a good response to chemotherapy compared to those with advanced stage. After chemotherapy, evaluation should be done to the patients' complaints and complete blood count to detect side effects. 
      PubDate: 2020-09-23
      DOI: 10.20473/fmi.v56i3.22164
      Issue No: Vol. 56, No. 3 (2020)
  • Effectiveness of Pre PRP Injection and Post Elevation Flap at Extended
           Random Flap Rat Skin

    • Authors: Thomas Eduardus Sudrajat Wahyu Nugroho, Sitti Rizaliyana, David S Perdanakusuma
      Pages: 186 - 191
      Abstract: Closure of the defect with a random skin flap is constrained by the extent of the defect area. Several studies have shown the benefits of administration of PRP (Platelet Rich Plasma) in random skin flap. The purpose of this study is to compare the effect of PRP injection given before flap elevation, after flap elevation and control on the extended random skin flap procedures in rats. This was an experimental study with randomized posttest-only control group design (n=27, divided into 3 treatment groups) that compare the effectiveness of PRP injection 24 hours prior to the elevation of the flap, after the elevation of the flap, and control in the extended random skin flap in rats. Random skin flap is made in the ratio 1: 5 on the rat skin. Measurement of viable area were observed on days 1, 7 and 14. There were significantly increased viability of random skin flap on the group with PRP injection 24 hours prior flap elevation compared to other group of treatment. The average of viability on day first 39%±13% ;42%±34%; 62%±14%. On day 7th 24%±13%; 36%±26%; 62%±12%. On day 14th 16%±15%; 28%±22%; 60%±11%. Injection of PRP on extended random skin flap on rat 24 hours before flap elevation increase viability of the flap compared to control group and group which receive PRP injection on extended random flap on rat skin after elevation of the flap. Viability increased due to angiogenesis stimulation after PRP injection.
      PubDate: 2020-09-23
      DOI: 10.20473/fmi.v56i3.22165
      Issue No: Vol. 56, No. 3 (2020)
  • Acid Phosphatase and Zinc Tests Are Effective for Semen Examination and
           Identification to Prove Intercourse

    • Authors: Ahmad Yudianto, Ariyanto Wibowo, Indah Nuraini, Htet Htet Aung
      Pages: 192 - 196
      Abstract: The presence of spermatozoa in vagina is a definite sign of sexual intercourse. However, sometimes microscopic examination does not find spermatozoa or reveals a false negative result. This is influenced by many factors, including the absence of ejaculate in the vaginal canal. In addition, there are other factors such as oligo/azoospermia, vasectomy, degeneration of sperm due to time, incorrect sampling, and improper storage. Therefore, examination of the other components of the ejaculate, ie. the enzyme acid phosphatase, choline and spermin, is important. Compared with spermatozoa, the enzyme phosphatase, choline and spermin have lower evidentiary value because these three components are less specific. However, the level of phosphatase enzyme found in the vagina is much lower than phosphatase enzyme that comes from prostate gland. In this study, as many as 192 samples in the form of patches with sperm/semen stains were tested with acid phosphatase test and zinc test through direct and indirect examination. Washing was carried out using 7 types of detergent for each 4 patch samples, and washing using water as control. The results showed very low sensitivity (0.186) and very high specificity (100%). This showed that both tests had high specificity values. Acid phosphatase test specifically showed the presence of the enzyme phosphatase, while zinc test specifically showed the presence of zinc in semen. This phosphohydrolase-phosphatase enzyme is easily degraded due to external factors, including temperature, humidity, and chemicals, ie. the element SDS (Sodium Dodecyl Sulfate) that has the ability to cut enzymes. The weakness of the acid phosphatase test is that this enzyme is easily degraded, either partially or completely, due to external factors, such as temperature, humidity, heat, and the presence of chemicals.
      PubDate: 2020-09-23
      DOI: 10.20473/fmi.v56i3.22184
      Issue No: Vol. 56, No. 3 (2020)
  • Mean Differences of Total Cholesterol Levels among Vegetarians and
           Non-Vegetarians at Maha Vihara Maitreya Duta Palembang, Indonesia

    • Authors: Lathifah Nudhar, Subandrate Subandrate, Susilawati Susilawati, Liniyanti Oswari
      Pages: 197 - 202
      Abstract: Total cholesterol level is one of the risk factor of cardiovascular disease. The proportion rate of hypercholesterolemia in Indonesia remains high, numbering around one third of (35.9%) Indonesians. Hypercholesterolemia is a modifiable risk factor, one of early measures that can be taken to prevent hypercholesterolemia is nutritional intervention. A dietary pattern high in plant sources and lower fat consumption has been recommended by several health organisation for prevention of hypercholesterolemia. This study was intended to determine mean difference of cholesterol level between vegetarian and nonvegetarian in Maha Vihara Maitreya Duta Palembang. This was an observational analytical study with cross-sectional design. A total of 173 subjects at Maha Vihara Maitreya Duta Palembang was included which consist of 80 Vegetarian and 93 Nonvegetarian. Measurement of total cholesterol level was done using rapid diagnostic test (RDT) Autocheck® Multi Monitoring System and parametric Independent T Test was chosen as method of statistical analysis. p<0.001 indicates significant differences of total cholesterol level between vegetarian (172.51± 39.05 mg/dL) and nonvegetarian (228.67±68.07 mg/dL) groups. The mean differences of total cholesterol of vegetarian group is 56,16 mg/dl lower than non vegetarian groups. A significant differences exist in total cholesterol level between vegetarian and non vegetarian group at Maha Vihara Maitreya Duta Palembang. Vegetarian groups has lower total cholesterol level compared to nonvegetarian.
      PubDate: 2020-09-23
      DOI: 10.20473/fmi.v56i3.22185
      Issue No: Vol. 56, No. 3 (2020)
  • Blood Type and Blood Pressure Correlations to Body Mass Index in Young

    • Authors: Bambang Edi Suwito, Viskasari P Kalanjati, Abdurachman Abdurachman
      Pages: 203 - 207
      Abstract: Specific ABO blood type was reported to the higher risk of having overweight and obesity. The laters had also been suggested to correlate to blood pressure. Here we studied blood type and blood pressure amongst seemingly healthy university students of IIKBW, Kediri to understand their correlations to the body mass index (BMI). The blood typing (ABO typing, Eryclone®) and blood pressure (automated digital sphygmomanometer) of 74 male and 76 female were measured in duplicate accordingly. The BMI was analysed from the student’s body weight and height using a digital balance and a microtoise staturemeter, respectively. Data were analysed using SPSS 17 with p<0.05 level of significance. There were 18.7% students have A blood type, 31.3% students were B type, 44% were O and 6.0% with AB blood type. There were 30.7% students with obesity, 18% overweight, 36% normal weight and 15.3% underweight. There were 4.7% had a hypertension, 28.7% pre-hypertension, and 66.7% were normal. No significant correlations found between BMI or the blood pressure to any specific ABO blood type, except between the blood pressure and the AB blood type (r=-0.179, p=0.03). However, there was a significant correlation between BMI and blood pressure (r=0.327, p=0.000). We observed no significant associations between any specific ABO blood type with the BMI and blood pressure. However, high blood pressures amongst students with obesity were found. Males were more common to suffer from obesity and high blood pressure than females.
      PubDate: 2020-09-23
      DOI: 10.20473/fmi.v56i3.22186
      Issue No: Vol. 56, No. 3 (2020)
  • Effectiveness of Antidiarrheal Unripe Wooden Banana (Musa paradisiaca L.)
           in Male Balb-C/Mice Induced with Escherichia coli

    • Authors: Arista Wahyu Ningsih, Maftuchah Rochmanti, Achmad Basori
      Pages: 208 - 215
      Abstract: The survey results in Indonesia in 2017 showed that the diarrhea morbidity rate for all age groups was 6.897.463. In Indonesia, unripe wooden banana has been used empirically as an antidiarrheal by the people in Senduro village, Lumajang, East Java. The study aimed to prove the antidiarrheal effect of ethanol extract of unripe wooden banana (Musa paradisiaca L.) in male Balb-C/mice induced by Escherichia coli bacteria. This study was a laboratory experimental study with post-test only control group design that used 40 mice divided into 8 groups, namely 1 group without treatment (normal mice) and 7 groups induced by Escherichia coli (1 negative control group given CMC-Na, 3 groups positive controls were given Loperamid HCL 0,5 mg/kgBW, 1 mg/kgBW and 2 mg/kgBW and 3 treatment groups were given extracts 100 mg/kgBW, 200 mg/kgBW and 400 mg/kgBW). Observation of animals in this study was carried out for 4 hours. Data were analyzed of frequency of diarrhea, fecal weight and fecal consistency used Kruskal Wallis and the results showed significant differences between treatment groups (p <0.05). From the results of the Mann-Whitney test, the ethanol extract of unripe wooden banana with a dose of 100 mg/kgBW was not significantly different (p> 0.05) with the control group of Loperamid HCL dose of 0.5 mg/kgBW. Unripe wooden banana had been shown to have antidiarrheal activity at an extract dose of 100 mg/kg BW in terms of the parameters of fecal consistency, frequency of diarrhea, and fecal weight. The results showed that the higher the dose, the better antidiarrheal activity.
      PubDate: 2020-09-23
      DOI: 10.20473/fmi.v56i3.22187
      Issue No: Vol. 56, No. 3 (2020)
  • Cochlear Dysfunction after Kanamycin Injection in Multidrug Resistant
           Tuberculosis Patients

    • Authors: Aditya Brahmono, Nyilo Purnami, Bakti Surarso
      Pages: 216 - 222
      Abstract: Long-term exposure to aminoglycoside such as kanamycin to cochlear cells is known to be associated with damage to outer hair cells in the organ Corti and type 1 sensory hair cells in the vestibular organs which ultimately causes permanent damage to hair cells. Hair cell damage occurs from the basal cochlea (high frequency area) to the apex cochlea (low frequency area) and followed by damage from the auditory nerve. Evaluation of cochlear dysfunction on multidrug resistant tuberculosis (MDR TB) patients have been rarely reported in the literature based on distortion product otoacoustic emission (DPOAE). Objectives: To prove cochlear dysfunction after kanamycin injection in MDR TB patient based on DPOAE examination of the overall frequencies and specific frequency. This was an observational longitudinal analytic with pre and post design without control group conducted in the infection division of MDR TB Outpatients Pulmonology Department and Otorhinolaryngology Community division of ORL-HNS Department, Dr. Soetomo General Hospital, Surabaya, within 3 months in 2018, 15 ear with the best baseline examination were taken by consecutive sampling and statistical analysis for cochlear dysfunction based on overall frequency and specific frequency DPOAE examination using Mc Nemar test. Based on DPOAE examination of overall frequencies there was no cochlear dysfunction (p>0.05) but a significant difference was found at frequency of 10,000 Hertz (Hz) (p=0.002). On ototoxicity monitoring there was no cochlear dysfunction after 4 weeks Kanamycin injection but cochlear dysfunction occurs at a specific frequency of 10,000 Hz.
      PubDate: 2020-09-23
      DOI: 10.20473/fmi.v56i3.22189
      Issue No: Vol. 56, No. 3 (2020)
  • Effect of High Fat Diet on Weight Loss Through the Expression of Uncouple
           Protein 1 in Mice Visceral Fat

    • Authors: Indira Syahraya, Hermina Novida, Lilik Herawati, Purwo Sri Rejeki
      Pages: 223 - 228
      Abstract: Obesity has become an epidemic around the world. High fat diet (HFD) have been implemented as one of intervention to battle obesity. Uncouple protein 1 (UCP1) is one of the key factor on energy expenditure. The aim of this experiment is to see the macronutrients composition on weight loss and UCP1 expression in the visceral fat. Fifty male mice, 2-3 months old, 18-30 grams, were put in five different groups. K1 (20% protein, 62.0% carbohydrate, 12% fat), K2 (60% protein, 0% carbohydrate, 30% fat), K3 (45% protein, 0% carbohydrate, 45% fat), K4 (30% protein, 0% carbohydrate, 60% fat), K5 (15% protein, 0% carbohydrate, 75% fat). The experiment was done in four weeks, mice body weight was measured every week. UCP1 expression seen using immunohistochemistry staining was measured at the end of the fourth week. Significant weight loss was achieved by K4 (-9.60±3.81) gram by the end of week four (p<0.05). K4 had the least amount of visceral fat. The result was that K4 achieved a significant visceral fat mass (0.02±0.06) gram compared to K1 (0.53±0.08) gram. Compared to other groups K5 expressed UCP1 more than the others (3.78±3.72) cphfp. HFD fed groups produced significant weight loss, group that had the greatest weight loss is K4. Meanwhile, each group had a variety of UCP1 expression.
      PubDate: 2020-09-23
      DOI: 10.20473/fmi.v56i3.22190
      Issue No: Vol. 56, No. 3 (2020)
  • In Vitro Characterization of Poly-Glycolyc Lactic-Co Acid (PLGA)
           â€“Collagen Based on Red Snapper Fish Scales (Lutjanus Sp.) Coating
           Chitosan as Duramater Artificial Candidate

    • Authors: Hajria Jabbar, Prihartini Widiyanti, Adanti Wido Paramadini, Dina Kartika Putri, Andini Isfandiary
      Pages: 229 - 234
      Abstract: Head trauma is the third cause of deaths with a high rank, causing severe head injury for 25.5%-54.9%. This study has been conducted by making a replacement layer of the brain (dura) to overcome the dural defect's impact by utilizing waste fish scales red snapper (Lutjanus Sp.). Synthesis brain membranes lining processed by casting method with each various chitosan coating concentrations of 1%, 1.5%, and 2%, then dried using vacuum dry. The samples were then characterized by tensile tests, FTIR, SEM, and MTT Assay. FTIR test results showed that red snipper scales could produce collagen powder at amide A group with stretching of –NH functional group, amide B group, has stretching of CH2 asymmetry, amide I area, amide II, and amide III area, which show –NH bonding. Tensile test results showed that the combination of PLGA-Collagen Chitosan Coating 2% produced the highest tensile strength is 4.8 MPa, which met human dura mater strength standards. MTT Assay results showed that the dural membrane produced no toxic seen from living cells reached 98.32%. Poly - Glycolic Lactic - Co Acid (PLGA) - collagen coating chitosan-based on red snapper fish scales (Lutjanus Sp.) composites has potency dura mater, artificial candidate, due to the chemistry, biological, and physical characteristics.
      PubDate: 2020-09-23
      DOI: 10.20473/fmi.v56i3.22191
      Issue No: Vol. 56, No. 3 (2020)
  • Case Report: Survival of A Coronavirus Disease-2019 (Covid-19) Patient
           with Acute Respiratory Distress Syndrome (ARDS) in Dr. Soetomo Hospital,
           Surabaya, Indonesia

    • Authors: Soedarsono Soedarsono, Bambang Pudjo Semedi, Rosy Setiawati, Resti Yudhawati Meliana, Tutik Kusmiati, Ariani Permatasari, Arief Bakhtiar, Irmi Syafa’ah, Dwi Wahyu Indrawanto
      Pages: 235 - 244
      Abstract: An outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that began in Wuhan, China has spread rapidly in multiple countries of the world and has become a pandemic. Currently, there is no vaccine or specific antiviral for COVID-19. A study reported 7.3% of critical patients admitted to ICU, 71% of them required mechanical ventilation, and 38.5% of them were survived. Herein, we reported a 54-year-old man with Acute Respiratory Distress Syndrome (ARDS) of COVID-19 who survived the disease. Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assay of nasopharyngeal and oropharingeal swabs were positive for SARS-CoV-2. Diagnosis of ARDS was also according to clinical symptoms, laboratory, chest radiograph, and chest CT scan. Alcaligenes faecalis and Candida albicans were also identified from sputum culture. Treatment for this patient was causal and supportive therapy, including antibiotic, antiviral, and antifungal therapy according to the culture results, fluid resuscitation, and oxygen supply from the mechanical ventilator. This patient was survived and discharged on hospital day-29. A fibrosis in parenchyma pulmonary and sensory peripheral neuropathy occurred after survived from ARDS. Monitoring of clinical, laboratory, and chest radiograph were continued after the patient discharged from the hospital. This case highlights the importance of early diagnosis and effective treatment to the care of COVID-19 patient.
      PubDate: 2020-09-23
      DOI: 10.20473/fmi.v56i3.22195
      Issue No: Vol. 56, No. 3 (2020)
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