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Publisher: Smart Science and Technology LLC   (Total: 21 journals)   [Sort by number of followers]

Showing 1 - 21 of 21 Journals sorted alphabetically
Abdomen     Open Access  
Cancer Cell & Microenvironment     Open Access   (Followers: 11)
Cardiovascular Regenerative Medicine     Open Access  
Evidence-based Medicine & Public Health     Open Access   (Followers: 8)
Immunoendocrinology     Open Access   (Followers: 1)
Inflammation and Cell Signaling     Open Access   (Followers: 3)
Itch & Pain     Open Access   (Followers: 2)
J. of Advanced Nutrition and Human Metabolism     Open Access   (Followers: 16)
Macrophage     Open Access  
Molecular & Cellular Epilepsy     Open Access   (Followers: 2)
Musculoskeletal Regeneration     Open Access   (Followers: 3)
Neurotransmitter     Open Access  
Precision Medicine     Open Access   (Followers: 2)
Receptors & Clinical Investigation     Open Access   (Followers: 1)
RNA & Disease     Open Access   (Followers: 1)
Science Proceedings     Open Access   (Followers: 1)
Stem Cell and Translational Investigation     Open Access   (Followers: 2)
Stem Cell Epigenetics     Open Access   (Followers: 3)
Telomere and Telomerase     Open Access  
Therapeutic Targets for Neurological Diseases     Open Access   (Followers: 1)
Uterus & Ovary     Open Access  
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Number of Followers: 0  

  This is an Open Access Journal Open Access journal
ISSN (Online) 2378-1351
Published by Smart Science and Technology LLC Homepage  [21 journals]
  • Nurse's role in the screening path of Colorectal Cancer

    • Authors: Emanuele Sinagra
      Abstract: The nurse has an important role in screening path of  colorectal cancer. It represents a point of reference for many patients who seek advice correct and accurate to solve many doubts and concerns that inevitably arise after receiving a letter of invitation to the prevention program. The nurse is involved in the emotional support at time of diagnosis of positivity of the fecal immunochemical test, in the information and support through treatment decision making, in the preparation for colonoscopy, and, finally, in the ongoing assessment and care during and after colonoscopy.
      PubDate: 2017-08-28
      DOI: 10.14800/abdomen.1586
      Issue No: Vol. 4 (2017)
  • Changes in the Microvasculature of Small Bowel Mesentery in Rats with
           Prehepatic Portal Hypertension: the Preliminary Study in vivo

    • Authors: Nikolay Olegovich Arefyev, Dmitry Victorovich Garbuzenko, Ilya Vladimirovich Emelyanov, Linar Rinatovich Khasanov, Lyubov’ Vladimirovna Mineeva
      Abstract: According to the literature, neoangiogenesis in the mesentery of the small intestine is the trigger of portosystemic collateral circulation in portal hypertension. However, the types of blood vessels involved in this process have not been established. The aim of this study was to determine which type of the mesenteric microvessels participates in angiogenesis in portal hypertension. Studies were performed in 12 adult outbred female rats weighing 250 ± 50 g which were divided into two groups: sham-operated (n = 5) and experimental (n = 7). The mesenteric microcirculation of rats in both groups was examined by intravital microscopy during the first laparotomy and relaparotomy on the 15th day of the experiment. In contrast to the sham-operated animals, prehepatic portal hypertension was induced in rats of the experimental group by partial portal vein ligation during the first operation. Portal pressure was measured in both groups at the time of the second operation. The portal pressure in rats of the experimental group was significantly higher than in sham-operated rats: 12,53 ± 1,26 mm Hg and 9,34 ± 0,14 mm Hg, respectively (p<0,01). There was a significant increase in the number of capillaries (p <0,05) and total vascular density (p <0,05) in rats of both groups by the 15th day of the experiment. At the same time, a greater increase in the capillary network was observed in rats of the experimental group (p <0,05), whereas no significant differences were found in the values of vascular density of the other types of blood vessels. Changes in the mesenteric microvasculature in portal hypertension lay in the increase in the values of vascular density, which occurred mostly at the expense of capillaries.
      PubDate: 2017-08-14
      DOI: 10.14800/abdomen.1580
      Issue No: Vol. 4 (2017)
  • Cardiac portion of the stomach: a deep region within the abdomen

    • Authors: kanji hirashima, Fengming Yue, Daihachiro Tomotsune, Katsunori Sasaki
      Abstract: The cardiac portion of the stomach is situated deeply in the upper abdomen and relatively well hidden. The topographic space around it is very narrow and complicated. These topographical features are produced by the liver, especially segments I, II, and III. An understanding of the relationships among compacted organs facilitates operative access by surgeons.
      PubDate: 2017-07-31
      DOI: 10.14800/abdomen.1550
      Issue No: Vol. 4 (2017)
  • The Role of Probiotics and Synbiotics in Preventing Postoperative Sepsis
           in Gastrointestinal Surgery

    • Authors: Christine SM Lau, Sudha Arumugam, Ronald S. Chamberlain
      Abstract: Sepsis is a potentially fatal condition, accounting for over 1 million hospitalizations annually in the United States, with mortality rates as high as 40%.  Patients undergoing gastrointestinal (GI) surgery are especially susceptible to sepsis, due to bacterial translocation secondary to surgical trauma and the use of antibiotics. Probiotics and synbiotics, which have been hypothesized to counteract disturbances in the intestinal flora and reduce pathogenic bacterial colonization, have been proposed for the prevention and treatment of a variety of GI conditions, including sepsis. Recent randomized control trials and meta-analyses evaluating the use of probiotic/symbiotic supplementation in elective surgical patients have demonstrated a significant reduction in the risk of developing postoperative sepsis in patients with the use of probiotic/synbiotics. Coupled with the prevention of numerous other GI symptoms, such as diarrhea, probiotics should be considered in all elective surgical GI patients.
      PubDate: 2016-12-05
      DOI: 10.14800/abdomen.1462
      Issue No: Vol. 3 (2016)
  • Phosphorylation-Mediated Interaction of Hepatitis C Virus NS5A and the
           Cellular YB-1 Controls HCV Propagation and the Early Stage of Viral RNA

    • Authors: Yan-Hwa Wu Lee, Wei-Ting Wang
      Abstract: About 130-150 million individuals worldwide are chronically infected by hepatitis C virus (HCV); HCV infection has become a leading cause of liver cirrhosis and hepatocellular carcinoma. The HCV life cycle relies on the cooperation of specific viral proteins and various cellular factors. The cellular protein Y-box binding protein 1 (YB-1) has recently been identified as a HCV host cofactor; however, its mechanism has not been fully characterized. The HCV nonstructural protein NS5A plays critical roles in almost every stage of HCV propagation, and has been proposed to control the switch between the defined stages of the HCV life cycle. Moreover, NS5A has recently emerged as a target for the development of novel anti-HCV drugs. Our studies have found that YB-1 not only interacts with NS5A, but also protects NS5A from degradation. Furthermore, both the NS5A/YB-1 interaction and the NS5A-stabilizing activity of YB-1 are dependent on the phosphorylation of YB-1 at serine 102 (S102). Interestingly, the YB-1 S102 site has previously been reported to be phosphorylated by Akt, which is in turn activated by HCV infection. Our study also reveals that DDX3, an YB-1-interacting partner, is another NS5A-binding protein, which plays a different role than YB-1 in HCV RNA replication and infectious virus production. Taken together, the elucidation of YB-1 participation in the HCV life cycle has led to a proposed mechanism of efficient virus propagation via coordination of the different stages of the viral life cycle through controlling stage-wise switches in the viral life cycle. Our finding also provides a novel niche for designing strategies for the development of new anti-HCV drugs by blocking specific virus-host interactions. 
      PubDate: 2016-03-22
      DOI: 10.14800/abdomen.1212
      Issue No: Vol. 3 (2016)
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
Tel: +00 44 (0)131 4513762
Fax: +00 44 (0)131 4513327
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