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Publisher: Elsevier   (Total: 3030 journals)

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Showing 1 - 200 of 3030 Journals sorted alphabetically
AASRI Procedia     Open Access   (Followers: 15)
Academic Pediatrics     Hybrid Journal   (Followers: 20, SJR: 1.402, h-index: 51)
Academic Radiology     Hybrid Journal   (Followers: 16, SJR: 1.008, h-index: 75)
Accident Analysis & Prevention     Partially Free   (Followers: 79, SJR: 1.109, h-index: 94)
Accounting Forum     Hybrid Journal   (Followers: 22, SJR: 0.612, h-index: 27)
Accounting, Organizations and Society     Hybrid Journal   (Followers: 27, SJR: 2.515, h-index: 90)
Achievements in the Life Sciences     Open Access   (Followers: 4)
Acta Anaesthesiologica Taiwanica     Open Access   (Followers: 5, SJR: 0.338, h-index: 19)
Acta Astronautica     Hybrid Journal   (Followers: 303, SJR: 0.726, h-index: 43)
Acta Automatica Sinica     Full-text available via subscription   (Followers: 3)
Acta Biomaterialia     Hybrid Journal   (Followers: 25, SJR: 2.02, h-index: 104)
Acta Colombiana de Cuidado Intensivo     Full-text available via subscription  
Acta de Investigación Psicológica     Open Access   (Followers: 2)
Acta Ecologica Sinica     Open Access   (Followers: 8, SJR: 0.172, h-index: 29)
Acta Haematologica Polonica     Free   (SJR: 0.123, h-index: 8)
Acta Histochemica     Hybrid Journal   (Followers: 3, SJR: 0.604, h-index: 38)
Acta Materialia     Hybrid Journal   (Followers: 196, SJR: 3.683, h-index: 202)
Acta Mathematica Scientia     Full-text available via subscription   (Followers: 5, SJR: 0.615, h-index: 21)
Acta Mechanica Solida Sinica     Full-text available via subscription   (Followers: 9, SJR: 0.442, h-index: 21)
Acta Oecologica     Hybrid Journal   (Followers: 9, SJR: 0.915, h-index: 53)
Acta Otorrinolaringologica (English Edition)     Full-text available via subscription   (Followers: 1)
Acta Otorrinolaringológica Española     Full-text available via subscription   (Followers: 3, SJR: 0.311, h-index: 16)
Acta Pharmaceutica Sinica B     Open Access   (Followers: 2)
Acta Poética     Open Access   (Followers: 4)
Acta Psychologica     Hybrid Journal   (Followers: 21, SJR: 1.365, h-index: 73)
Acta Sociológica     Open Access  
Acta Tropica     Hybrid Journal   (Followers: 5, SJR: 1.059, h-index: 77)
Acta Urológica Portuguesa     Open Access  
Actas Dermo-Sifiliograficas     Full-text available via subscription   (Followers: 4)
Actas Dermo-Sifiliográficas (English Edition)     Full-text available via subscription   (Followers: 3)
Actas Urológicas Españolas     Full-text available via subscription   (Followers: 3, SJR: 0.383, h-index: 19)
Actas Urológicas Españolas (English Edition)     Full-text available via subscription   (Followers: 2)
Actualites Pharmaceutiques     Full-text available via subscription   (Followers: 5, SJR: 0.141, h-index: 3)
Actualites Pharmaceutiques Hospitalieres     Full-text available via subscription   (Followers: 4, SJR: 0.112, h-index: 2)
Acupuncture and Related Therapies     Hybrid Journal   (Followers: 4)
Ad Hoc Networks     Hybrid Journal   (Followers: 11, SJR: 0.967, h-index: 57)
Addictive Behaviors     Hybrid Journal   (Followers: 15, SJR: 1.514, h-index: 92)
Addictive Behaviors Reports     Open Access   (Followers: 5)
Additive Manufacturing     Hybrid Journal   (Followers: 7, SJR: 1.039, h-index: 5)
Additives for Polymers     Full-text available via subscription   (Followers: 20)
Advanced Drug Delivery Reviews     Hybrid Journal   (Followers: 120, SJR: 5.2, h-index: 222)
Advanced Engineering Informatics     Hybrid Journal   (Followers: 11, SJR: 1.265, h-index: 53)
Advanced Powder Technology     Hybrid Journal   (Followers: 16, SJR: 0.739, h-index: 33)
Advances in Accounting     Hybrid Journal   (Followers: 8, SJR: 0.299, h-index: 15)
Advances in Agronomy     Full-text available via subscription   (Followers: 15, SJR: 2.071, h-index: 82)
Advances in Anesthesia     Full-text available via subscription   (Followers: 24, SJR: 0.169, h-index: 4)
Advances in Antiviral Drug Design     Full-text available via subscription   (Followers: 3)
Advances in Applied Mathematics     Full-text available via subscription   (Followers: 6, SJR: 1.054, h-index: 35)
Advances in Applied Mechanics     Full-text available via subscription   (Followers: 10, SJR: 0.801, h-index: 26)
Advances in Applied Microbiology     Full-text available via subscription   (Followers: 21, SJR: 1.286, h-index: 49)
Advances In Atomic, Molecular, and Optical Physics     Full-text available via subscription   (Followers: 16, SJR: 3.31, h-index: 42)
Advances in Biological Regulation     Hybrid Journal   (Followers: 4, SJR: 2.277, h-index: 43)
Advances in Botanical Research     Full-text available via subscription   (Followers: 3, SJR: 0.619, h-index: 48)
Advances in Cancer Research     Full-text available via subscription   (Followers: 26, SJR: 2.215, h-index: 78)
Advances in Carbohydrate Chemistry and Biochemistry     Full-text available via subscription   (Followers: 9, SJR: 0.9, h-index: 30)
Advances in Catalysis     Full-text available via subscription   (Followers: 5, SJR: 2.139, h-index: 42)
Advances in Cellular and Molecular Biology of Membranes and Organelles     Full-text available via subscription   (Followers: 12)
Advances in Chemical Engineering     Full-text available via subscription   (Followers: 24, SJR: 0.183, h-index: 23)
Advances in Child Development and Behavior     Full-text available via subscription   (Followers: 10, SJR: 0.665, h-index: 29)
Advances in Chronic Kidney Disease     Full-text available via subscription   (Followers: 8, SJR: 1.268, h-index: 45)
Advances in Clinical Chemistry     Full-text available via subscription   (Followers: 28, SJR: 0.938, h-index: 33)
Advances in Colloid and Interface Science     Full-text available via subscription   (Followers: 18, SJR: 2.314, h-index: 130)
Advances in Computers     Full-text available via subscription   (Followers: 16, SJR: 0.223, h-index: 22)
Advances in Developmental Biology     Full-text available via subscription   (Followers: 11)
Advances in Digestive Medicine     Open Access   (Followers: 4)
Advances in DNA Sequence-Specific Agents     Full-text available via subscription   (Followers: 5)
Advances in Drug Research     Full-text available via subscription   (Followers: 22)
Advances in Ecological Research     Full-text available via subscription   (Followers: 39, SJR: 3.25, h-index: 43)
Advances in Engineering Software     Hybrid Journal   (Followers: 25, SJR: 0.486, h-index: 10)
Advances in Experimental Biology     Full-text available via subscription   (Followers: 7)
Advances in Experimental Social Psychology     Full-text available via subscription   (Followers: 38, SJR: 5.465, h-index: 64)
Advances in Exploration Geophysics     Full-text available via subscription   (Followers: 3)
Advances in Fluorine Science     Full-text available via subscription   (Followers: 8)
Advances in Food and Nutrition Research     Full-text available via subscription   (Followers: 41, SJR: 0.674, h-index: 38)
Advances in Fuel Cells     Full-text available via subscription   (Followers: 14)
Advances in Genetics     Full-text available via subscription   (Followers: 15, SJR: 2.558, h-index: 54)
Advances in Genome Biology     Full-text available via subscription   (Followers: 11)
Advances in Geophysics     Full-text available via subscription   (Followers: 6, SJR: 2.325, h-index: 20)
Advances in Heat Transfer     Full-text available via subscription   (Followers: 18, SJR: 0.906, h-index: 24)
Advances in Heterocyclic Chemistry     Full-text available via subscription   (Followers: 8, SJR: 0.497, h-index: 31)
Advances in Human Factors/Ergonomics     Full-text available via subscription   (Followers: 22)
Advances in Imaging and Electron Physics     Full-text available via subscription   (Followers: 2, SJR: 0.396, h-index: 27)
Advances in Immunology     Full-text available via subscription   (Followers: 33, SJR: 4.152, h-index: 85)
Advances in Inorganic Chemistry     Full-text available via subscription   (Followers: 9, SJR: 1.132, h-index: 42)
Advances in Insect Physiology     Full-text available via subscription   (Followers: 3, SJR: 1.274, h-index: 27)
Advances in Integrative Medicine     Hybrid Journal   (Followers: 4)
Advances in Intl. Accounting     Full-text available via subscription   (Followers: 4)
Advances in Life Course Research     Hybrid Journal   (Followers: 7, SJR: 0.764, h-index: 15)
Advances in Lipobiology     Full-text available via subscription   (Followers: 1)
Advances in Magnetic and Optical Resonance     Full-text available via subscription   (Followers: 8)
Advances in Marine Biology     Full-text available via subscription   (Followers: 16, SJR: 1.645, h-index: 45)
Advances in Mathematics     Full-text available via subscription   (Followers: 10, SJR: 3.261, h-index: 65)
Advances in Medical Sciences     Hybrid Journal   (Followers: 5, SJR: 0.489, h-index: 25)
Advances in Medicinal Chemistry     Full-text available via subscription   (Followers: 5)
Advances in Microbial Physiology     Full-text available via subscription   (Followers: 4, SJR: 1.44, h-index: 51)
Advances in Molecular and Cell Biology     Full-text available via subscription   (Followers: 21)
Advances in Molecular and Cellular Endocrinology     Full-text available via subscription   (Followers: 10)
Advances in Molecular Toxicology     Full-text available via subscription   (Followers: 6, SJR: 0.324, h-index: 8)
Advances in Nanoporous Materials     Full-text available via subscription   (Followers: 3)
Advances in Oncobiology     Full-text available via subscription   (Followers: 3)
Advances in Organometallic Chemistry     Full-text available via subscription   (Followers: 15, SJR: 2.885, h-index: 45)
Advances in Parallel Computing     Full-text available via subscription   (Followers: 7, SJR: 0.148, h-index: 11)
Advances in Parasitology     Full-text available via subscription   (Followers: 7, SJR: 2.37, h-index: 73)
Advances in Pediatrics     Full-text available via subscription   (Followers: 20, SJR: 0.4, h-index: 28)
Advances in Pharmaceutical Sciences     Full-text available via subscription   (Followers: 14)
Advances in Pharmacology     Full-text available via subscription   (Followers: 13, SJR: 1.718, h-index: 58)
Advances in Physical Organic Chemistry     Full-text available via subscription   (Followers: 7, SJR: 0.384, h-index: 26)
Advances in Phytomedicine     Full-text available via subscription  
Advances in Planar Lipid Bilayers and Liposomes     Full-text available via subscription   (Followers: 3, SJR: 0.248, h-index: 11)
Advances in Plant Biochemistry and Molecular Biology     Full-text available via subscription   (Followers: 8)
Advances in Plant Pathology     Full-text available via subscription   (Followers: 5)
Advances in Porous Media     Full-text available via subscription   (Followers: 4)
Advances in Protein Chemistry     Full-text available via subscription   (Followers: 18)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 17, SJR: 1.5, h-index: 62)
Advances in Psychology     Full-text available via subscription   (Followers: 56)
Advances in Quantum Chemistry     Full-text available via subscription   (Followers: 5, SJR: 0.478, h-index: 32)
Advances in Radiation Oncology     Open Access  
Advances in Small Animal Medicine and Surgery     Hybrid Journal   (Followers: 1, SJR: 0.1, h-index: 2)
Advances in Space Research     Full-text available via subscription   (Followers: 332, SJR: 0.606, h-index: 65)
Advances in Structural Biology     Full-text available via subscription   (Followers: 7)
Advances in Surgery     Full-text available via subscription   (Followers: 6, SJR: 0.823, h-index: 27)
Advances in the Study of Behavior     Full-text available via subscription   (Followers: 28, SJR: 1.321, h-index: 56)
Advances in Veterinary Medicine     Full-text available via subscription   (Followers: 14)
Advances in Veterinary Science and Comparative Medicine     Full-text available via subscription   (Followers: 12)
Advances in Virus Research     Full-text available via subscription   (Followers: 5, SJR: 1.878, h-index: 68)
Advances in Water Resources     Hybrid Journal   (Followers: 42, SJR: 2.408, h-index: 94)
Aeolian Research     Hybrid Journal   (Followers: 5, SJR: 0.973, h-index: 22)
Aerospace Science and Technology     Hybrid Journal   (Followers: 304, SJR: 0.816, h-index: 49)
AEU - Intl. J. of Electronics and Communications     Hybrid Journal   (Followers: 8, SJR: 0.318, h-index: 36)
African J. of Emergency Medicine     Open Access   (Followers: 4, SJR: 0.344, h-index: 6)
Ageing Research Reviews     Hybrid Journal   (Followers: 7, SJR: 3.289, h-index: 78)
Aggression and Violent Behavior     Hybrid Journal   (Followers: 390, SJR: 1.385, h-index: 72)
Agri Gene     Hybrid Journal  
Agricultural and Forest Meteorology     Hybrid Journal   (Followers: 15, SJR: 2.18, h-index: 116)
Agricultural Systems     Hybrid Journal   (Followers: 29, SJR: 1.275, h-index: 74)
Agricultural Water Management     Hybrid Journal   (Followers: 36, SJR: 1.546, h-index: 79)
Agriculture and Agricultural Science Procedia     Open Access  
Agriculture and Natural Resources     Open Access   (Followers: 1)
Agriculture, Ecosystems & Environment     Hybrid Journal   (Followers: 48, SJR: 1.879, h-index: 120)
Ain Shams Engineering J.     Open Access   (Followers: 5, SJR: 0.434, h-index: 14)
Air Medical J.     Hybrid Journal   (Followers: 3, SJR: 0.234, h-index: 18)
AKCE Intl. J. of Graphs and Combinatorics     Open Access   (SJR: 0.285, h-index: 3)
Alcohol     Hybrid Journal   (Followers: 9, SJR: 0.922, h-index: 66)
Alcoholism and Drug Addiction     Open Access   (Followers: 5)
Alergologia Polska : Polish J. of Allergology     Full-text available via subscription   (Followers: 1)
Alexandria Engineering J.     Open Access   (Followers: 1, SJR: 0.436, h-index: 12)
Alexandria J. of Medicine     Open Access  
Algal Research     Partially Free   (Followers: 7, SJR: 2.05, h-index: 20)
Alkaloids: Chemical and Biological Perspectives     Full-text available via subscription   (Followers: 3)
Allergologia et Immunopathologia     Full-text available via subscription   (Followers: 1, SJR: 0.46, h-index: 29)
Allergology Intl.     Open Access   (Followers: 5, SJR: 0.776, h-index: 35)
ALTER - European J. of Disability Research / Revue Européenne de Recherche sur le Handicap     Full-text available via subscription   (Followers: 6, SJR: 0.158, h-index: 9)
Alzheimer's & Dementia     Hybrid Journal   (Followers: 45, SJR: 4.289, h-index: 64)
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring     Open Access   (Followers: 5)
Alzheimer's & Dementia: Translational Research & Clinical Interventions     Open Access   (Followers: 3)
American Heart J.     Hybrid Journal   (Followers: 45, SJR: 3.157, h-index: 153)
American J. of Cardiology     Hybrid Journal   (Followers: 47, SJR: 2.063, h-index: 186)
American J. of Emergency Medicine     Hybrid Journal   (Followers: 34, SJR: 0.574, h-index: 65)
American J. of Geriatric Pharmacotherapy     Full-text available via subscription   (Followers: 6, SJR: 1.091, h-index: 45)
American J. of Geriatric Psychiatry     Hybrid Journal   (Followers: 14, SJR: 1.653, h-index: 93)
American J. of Human Genetics     Hybrid Journal   (Followers: 32, SJR: 8.769, h-index: 256)
American J. of Infection Control     Hybrid Journal   (Followers: 25, SJR: 1.259, h-index: 81)
American J. of Kidney Diseases     Hybrid Journal   (Followers: 31, SJR: 2.313, h-index: 172)
American J. of Medicine     Hybrid Journal   (Followers: 48, SJR: 2.023, h-index: 189)
American J. of Medicine Supplements     Full-text available via subscription   (Followers: 3)
American J. of Obstetrics and Gynecology     Hybrid Journal   (Followers: 174, SJR: 2.255, h-index: 171)
American J. of Ophthalmology     Hybrid Journal   (Followers: 51, SJR: 2.803, h-index: 148)
American J. of Ophthalmology Case Reports     Open Access   (Followers: 2)
American J. of Orthodontics and Dentofacial Orthopedics     Full-text available via subscription   (Followers: 6, SJR: 1.249, h-index: 88)
American J. of Otolaryngology     Hybrid Journal   (Followers: 22, SJR: 0.59, h-index: 45)
American J. of Pathology     Hybrid Journal   (Followers: 23, SJR: 2.653, h-index: 228)
American J. of Preventive Medicine     Hybrid Journal   (Followers: 21, SJR: 2.764, h-index: 154)
American J. of Surgery     Hybrid Journal   (Followers: 32, SJR: 1.286, h-index: 125)
American J. of the Medical Sciences     Hybrid Journal   (Followers: 13, SJR: 0.653, h-index: 70)
Ampersand : An Intl. J. of General and Applied Linguistics     Open Access   (Followers: 5)
Anaerobe     Hybrid Journal   (Followers: 4, SJR: 1.066, h-index: 51)
Anaesthesia & Intensive Care Medicine     Full-text available via subscription   (Followers: 52, SJR: 0.124, h-index: 9)
Anaesthesia Critical Care & Pain Medicine     Full-text available via subscription   (Followers: 3)
Anales de Cirugia Vascular     Full-text available via subscription  
Anales de Pediatría     Full-text available via subscription   (Followers: 2, SJR: 0.209, h-index: 27)
Anales de Pediatría (English Edition)     Full-text available via subscription  
Anales de Pediatría Continuada     Full-text available via subscription   (SJR: 0.104, h-index: 3)
Analytic Methods in Accident Research     Hybrid Journal   (Followers: 2, SJR: 2.577, h-index: 7)
Analytica Chimica Acta     Hybrid Journal   (Followers: 38, SJR: 1.548, h-index: 152)
Analytical Biochemistry     Hybrid Journal   (Followers: 154, SJR: 0.725, h-index: 154)
Analytical Chemistry Research     Open Access   (Followers: 7, SJR: 0.18, h-index: 2)
Analytical Spectroscopy Library     Full-text available via subscription   (Followers: 10)
Anesthésie & Réanimation     Full-text available via subscription  
Anesthesiology Clinics     Full-text available via subscription   (Followers: 21, SJR: 0.421, h-index: 40)
Angiología     Full-text available via subscription   (SJR: 0.124, h-index: 9)
Angiologia e Cirurgia Vascular     Open Access  
Animal Behaviour     Hybrid Journal   (Followers: 143, SJR: 1.907, h-index: 126)
Animal Feed Science and Technology     Hybrid Journal   (Followers: 5, SJR: 1.151, h-index: 83)
Animal Reproduction Science     Hybrid Journal   (Followers: 5, SJR: 0.711, h-index: 78)
Annales d'Endocrinologie     Full-text available via subscription   (SJR: 0.394, h-index: 30)
Annales d'Urologie     Full-text available via subscription  
Annales de Cardiologie et d'Angéiologie     Full-text available via subscription   (SJR: 0.177, h-index: 13)
Annales de Chirurgie de la Main et du Membre Supérieur     Full-text available via subscription  
Annales de Chirurgie Plastique Esthétique     Full-text available via subscription   (Followers: 2, SJR: 0.354, h-index: 22)
Annales de Chirurgie Vasculaire     Full-text available via subscription   (Followers: 1)

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Journal Cover Advances in Radiation Oncology
  [0 followers]  Follow
    
  This is an Open Access Journal Open Access journal
   ISSN (Online) 2452-1094
   Published by Elsevier Homepage  [3030 journals]
  • Orthogonal Image Pairs Coupled with OSMS for Non-Coplanar Beam Angle
           Intracranial Single-Isocenter SRS Treatments with Multiple Targets on the
           Varian Edge™ Radiosurgery System

    • Authors: Jasmine A. Oliver; Patrick Kelly, Sanford L. Meeks, Twyla R. Willoughby, Amish P. Shah
      Abstract: To reduce the number of CBCTs during SRS treatments, we characterized the accuracy of non-coplanar IGRT on the Varian EDGE™ Radiosurgery System for intracranial SRS treatments using a CIRS head phantom and Encompass SRS Immobilization System by determining collision-free space that orthogonal pairs can be obtained and assessing accuracy of kV-kV orthogonal pair registration with OSMS monitoring relative to CBCT as the gold standard. This technique provides accurate and safe treatments with negligible dosimetric effects.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-04-26
      DOI: 10.1016/j.adro.2017.04.006
       
  • Incorporating Big Data into Treatment Plan Evaluation – Development of
           Statistical DVH Metrics and Visualization Dashboards

    • Authors: Charles Mayo; John Yao, Avraham Eisbruch, James Balter, Dale Litzenberg, Martha Matuszak, Marc Kessler, Grant Weyburn, Carlos Anderson, Dawn Owen, William Jackson, Randall Ten Haken
      Abstract: We demonstrate the utility of an in house developed DVH-based metrics and visualization method. Use of the metrics to summarize historical experience for two patient groups: 1) head and neck and 2) prostate patients was demonstrated. This tool allows for simple and intuitive quantification of the comparison of individual treatment plans against historical experiences. As such, this may allow for superior treatment planning which has the potential to result in improved patient care.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-04-26
      DOI: 10.1016/j.adro.2017.04.005
       
  • Diffuse large B- cell lymphoma in very elderly patients over 80 years old:
           incorporating consolidative radiation therapy into management decisions

    • Authors: Chelsea C. Pinnix; Therese Y. Andraos, Bouthaina Dabaja, Sarah Milgrom, Grace Smith, Dai Chihara, Andrea Ng, Luis E. Fayad, Yasuhiro Oki, Sattva Neelapu, Jason Westin, M. Alma Rodriguez, Loretta J. Nastoupil
      Abstract: In a cohort of 131 patients with DLBCL age 80 and older with chemo-sensitive disease, outcomes rivaled those of younger patients. For limited stage disease, abbreviated chemotherapy followed by consolidative radiation therapy was equivalent in efficacy to chemotherapy alone (6-8 cycles), but was associated with lower rates of myelosuppression, neuropathy and congestive heart failure. In advanced stage patients, radiation therapy appeared to improve local control. Older patients should be considered for consolidative RT after immunochemotherapy.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-04-21
      DOI: 10.1016/j.adro.2017.04.004
       
  • Reducing Radiation Dose and Enhancing Imaging Quality of 4DCT for
           Radiation Therapy Using Iterative Reconstruction Algorithms

    • Authors: George Noid; An Tai, Guang-Pei Chen, Jared Robbins, X. Allen Li
      Abstract: Time sorted 4DCT scans are used in radiation therapy (RT) for motion management; however these scans are associated with elevated dose to the patient. Iterative image reconstruction algorithms are known to reduce the imaging dose by 30-50% while maintaining the signal to noise ratio. The study aims to evaluate whether one such iterative reconstruction algorithm, SAFIRE, can reduce imaging dose while maintaining the necessary contrast-to-noise to generate clinically valid 4DCT datasets.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-04-21
      DOI: 10.1016/j.adro.2017.04.003
       
  • Long Term Survival and Toxicity Outcomes of Intensity-Modulated Radiation
           Therapy for the Treatment of Esophageal Cancer: A Large
           Single-Institutional Cohort Study

    • Authors: Anhui Shi; Zhongxing Liao, Pamela K. Allen, Linus Ho, Mariela Blum Murphy, Dipen M. Maru, Stephen G. Swisher, Wayne L. Hofstetter, Reza J. Mehran, James D. Cox, Ritsuko Komaki, Steven H. Lin
      Abstract: Radiotherapy is an integral part in the management of esophageal cancer. While the current standard is 3D conformal radiotherapy, Intensity Modulated Radiation Therapy (IMRT) affords improved organ sparing effects over the 3D technique. However, reported clinical experience using IMRT has been sparse. Herein we report the largest single institutional experience using IMRT, demonstrating excellent toxicity and survival outcomes relative to historical controls for patients treated with neoadjuvant or definitive chemoradiotherapy.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-04-18
      DOI: 10.1016/j.adro.2017.04.002
       
  • Preoperative radiation dose escalation for rectal cancer using a
           concomitant boost strategy improves tumor downstaging without increasing
           toxicity: A matched-pair analysis

    • Authors: Jillian R. Gunther; Awalpreet S. Chadha, Ui Sup Shin, In Ja Park, Kiran V. Kattepogu, Jonathan D. Grant, David C. Weksberg, Cathy Eng, Scott E. Kopetz, Prajnan Das, Marc E. Delclos, Harmeet Kaur, Dipen M. Maru, John M. Skibber, Miguel A. Rodriguez-Bigas, Y Nancy You, Sunil Krishnan, George J. Chang.
      Abstract: Locally advanced rectal cancer (LARC) patients who achieve complete pathologic response after neoadjuvant chemoradiation experience improved outcomes. Radiation dose escalation has been shown to improve rates of tumor response. We conducted a case-control study of LARC patients who received standard dose or concomitant boost chemoradiation prior to surgical resection. Boost patients had improved tumor downstaging and local control without increases in early or late toxicity including surgical complications.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-04-11
      DOI: 10.1016/j.adro.2017.04.001
       
  • Adjuvant radiation for salivary gland malignancies is associated with
           improved survival: A national cancer database analysis

    • Authors: Richard L. Bakst; William Su, Umut Ozbek, Miriam A. Knoll, Brett A. Miles, Vishal Gupta, Ryan Rhome
      Abstract: We aimed to investigate whether adjuvant radiation improves overall survival in major salivary gland cancers. Furthermore, we wanted to identify which subset of patients benefits the most from receiving radiation. 8243 patients with salivary gland cancer were identified from the NCDB. Patients in the high-risk group had greater survival (HR = 0.76; p=.002) if they received adjuvant radiation therapy.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-04-05
      DOI: 10.1016/j.adro.2017.03.008
       
  • 4-1BB (CD137) and radiotherapy: A Case report and Literature Review

    • Authors: Jay Shiao; Nathan Bowers, Tahseen H. Nasti, Faisal Khosa, Mohammad K. Khan
      Abstract: Emerging immuno-oncology combination strategies include utilizing radiotherapy (RT) with immunotherapeutic checkpoint blockade monoclonal antibodies (mAbs) such as CTLA-4 and PD-1, represent a new and exciting strategy to improve outcomes in solid tumor malignancies [1, 2]. RT has the potential to augment immune responses [3, 4], and cancer cells destroyed by RT are considered to be a source of tumor associated antigens that can be processed by professional antigen presenting cells (APCs) [5].
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-04-03
      DOI: 10.1016/j.adro.2017.03.007
       
  • Dosimetric and Clinical Outcomes After Volumetric Modulated arc Therapy
           for Carcinoma of the Thoracic Esophagus

    • Authors: Cai Xu; Mian Xi, Ritsuko Komaki, Peter A. Balter, Meilin Huang, Brian P. Hobbs, Luhua Wang, Steven H. Lin
      Abstract: Outcomes after Volumetric Modulated Arc Therapy (VMAT) for thoracic esophageal carcinoma are largely unknown. We conducted a propensity matched analysis of 65 patients treated with VMAT and concurrent chemotherapy with 130 patients treated with step-and-shoot (ss)IMRT and concurrent chemotherapy and found VMAT had better target conformity with comparable toxicity, response, recurrence and survival outcomes. VMAT is an efficient, safe and effective radiation delivery method for the treatment of esophageal cancer.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-03-27
      DOI: 10.1016/j.adro.2017.03.006
       
  • Simulating Intrafraction Prostate Motion with a Random Walk Model

    • Authors: Tobias Pommer; Jung Hun Oh, Per Munck af Rosenschöld, Joseph O. Deasy
      Abstract: Prostate motion during radiotherapy is one of the factors limiting its accuracy. In this study, we modeled prostate motion as a random walk. With access to time-resolved prostate motion during radiotherapy from 17 patients we performed a detailed analysis and time-resolved simulations. We found that random walk is a viable option for prostate motion modeling and can potentially be used to simulate radiotherapy delivery and analyze treatment margins.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-03-27
      DOI: 10.1016/j.adro.2017.03.005
       
  • Patient-Reported Distress and Survival Among Patients Receiving Definitive
           Radiotherapy

    • Authors: Yacob Habboush; Robert P. Shannon, Shehzad K. Niazi, Laeticia Hollant, Megan Single, Kate Gaines, Bridget Smart, Nicolette T. Chimato, Michael G. Heckman, Steven J. Buskirk, Laura A. Vallow, Katherine S. Tzou, Stephen J. Ko, Jennifer L. Peterson, Heather A. Biers, Atiya B. Day, Kimberly A. Nelson, Jeff A. Sloan, Michele Y. Halyard, Robert C. Miller
      Abstract: Patient-reported distress (PRD) has not been assessed in association with survival after radiotherapy (RT). This study aimed to evaluate the association between PRD level and survival after definitive RT by retrospectively reviewing a PRD questionnaire completed by patients undergoing definitive RT. The study showed that higher distress is associated with decreased survival.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-03-21
      DOI: 10.1016/j.adro.2017.03.004
       
  • ACR Appropriateness Criteria® External Beam Radiation Therapy Treatment
           Planning for Clinically Localized Prostate Cancer, Part II of II

    • Authors: Expert Panel on Radiation Oncology–Prostate; Nicholas G. Zaorsky, Timothy N. Showalter, Gary A. Ezzell, Paul L. Nguyen, Dean G. Assimos, Anthony V. D'Amico, Alexander R. Gottschalk, Gary S. Gustafson, Sameer R. Keole, Stanley L. Liauw, Shane Lloyd, Patrick W. McLaughlin, Benjamin Movsas, Bradley R. Prestidge, Al V. Taira, Neha Vapiwala, Brian J. Davis
      Abstract: To (1) present the most updated American College of Radiology Appropriateness Criteria formed from an expert panel on the appropriate delivery of external beam radiation to manage stage T1 and T2 prostate cancer (in the definitive setting and post-prostatectomy); and (2) provide clinical variants with expert recommendations, based on an accompanying Appropriateness Criteria for target volumes and treatment planning.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-03-21
      DOI: 10.1016/j.adro.2017.03.003
       
  • Dose escalation with an IMRT technique in 15 to 28 fractions is better
           tolerated than standard doses of 3DCRT for LAPC

    • Authors: Lauren E. Colbert; Shalini Moningi, Awalpreet Chadha, Ahmed Amer, Yeonju Lee, Robert A. Wolff, Gauri Varadhachary, Jason Fleming, Matthew Katz, Prajnan Das, Sunil Krishnan, Eugene J. Koay, Peter Park, Christopher H. Crane, Cullen M. Taniguchi
      Abstract: Patients with LAPC who received induction chemotherapy followed by chemoradiation with definitive intent between 2005 and 2016 were reviewed. Toxicities for patients treated with escalated dose radiation therapy (EDR) utilizing an intensity modulated radiation therapy technique were recorded. Overall acute and late toxicity rates with EDR were low. Patients experienced lower gastrointestinal and overall toxicity as compared to patients treated with conventional doses and 3D conformal techniques.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-03-18
      DOI: 10.1016/j.adro.2017.02.004
       
  • Audiovisual biofeedback guided breath-hold improves lung tumor position
           reproducibility and volume consistency

    • Authors: Danny Lee; Peter B. Greer, Carminia Lapuz, Joanna Ludbrook, Perry Hunter, Jameen Arm, Sean Pollock, Kuldeep Makhija, Ricky T. O'Brien, Taeho Kim, Paul Keall
      Abstract: We investigated the impact of audiovisual biofeedback breath-hold guidance on MRI measured lung tumor position reproducibility and volume consistency. Inhalation and exhalation breath-hold positions determined in a breath-hold training session were utilized across two MRI sessions (pre- and mid-treatment). Inter-fraction lung tumor position and volume were significantly more reproducible and consistent respectively when utilizing audiovisual biofeedback breath-hold compared to conventional breath-hold with audio-instructions alone.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-03-09
      DOI: 10.1016/j.adro.2017.03.002
       
  • Effects of Vertebral Body Sparing Proton Craniospinal Irradiation on the
           Spine of Young Pediatric Patients with Medulloblastoma

    • Authors: Iain MacEwan; Brian Chou, Jeremy Moretz, Lilia Loredo, David Bush, Jerry D. Slater
      Abstract: This retrospective review evaluated the long-term consequences of vertebral body sparing proton CSI on young children with medulloblastoma. Clinical endpoints were measured including chronic back pain, diagnosis of scoliosis, and need for spine surgery. Radiographic endpoints were measured including scoliosis and changes in vertebral body height, as well as bone marrow changes in the vertebral body. With this limited cohort we found no severe spinal toxicities from this treatment technique and excellent disease control.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-03-09
      DOI: 10.1016/j.adro.2017.03.001
       
  • Intensity Modulated Radiation Therapy for Squamous Cell Carcinoma of the
           Vulva: Treatment Technique and Outcomes

    • Authors: Yuan James Rao; Anupama Chundury, Julie K. Schwarz, Comron Hassanzadeh, Todd DeWees, Daniel Mullen, Matthew A. Powell, David G. Mutch, Perry W. Grigsby
      Abstract: We present the treatment technique and outcomes from a retrospective review of 39 patients with squamous cell carcinoma of the vulva treated with IMRT. The 3-year locoregional control was 89% in patients treated post-operatively, and 42% in patients treated definitively. Complete pathological response was observed in 44% of patients treated with definitive or neoadjuvant IMRT. There was limited acute and late toxicity.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-02-28
      DOI: 10.1016/j.adro.2017.02.006
       
  • Preserving the legacy of re-irradiation: a narrative review of historical
           publications

    • Authors: Carsten Nieder; Johannes A. Langendijk, Matthias Guckenberger, Anca L. Grosu
      Abstract: Both hematological malignancies and solid tumors were treated with a second course of radiotherapy already in the first half of the 20th century and indications included local relapse, regional nodal recurrence and second primary tumors developing in a previously treated region. Treatment approaches included external beam radiotherapy, brachytherapy or combinations thereof. Breast cancer, gynecological tumors, head and neck, brain and skin tumors are among the entities included in this review.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-02-28
      DOI: 10.1016/j.adro.2017.02.005
       
  • 18F-FDG PET response and clinical outcomes after stereotactic body
           radiotherapy for metastatic melanoma

    • Authors: Ryan S. Youland; Ann T. Packard, Miran J. Blanchard, Andrea L. Arnett, Gregory A. Wiseman, Lisa A. Kottschade, Roxana S. Dronca, Svetomir N. Markovic, Kenneth R. Olivier, Sean S. Park
      Abstract: This study assessed outcomes for oligometastatic malignant melanoma treated with stereotactic body radiotherapy (SBRT). Patients with pre- and post-treatment 18F-FDG-PET/CT scans were included. Metastasis control was excellent after SBRT and majority of patients achieved a complete metabolic response. Single-fraction equivalent dose > 24 Gy resulted in the optimal metastasis control. Prospectively captured acute and late toxicity were minimal. SBRT should be discussed with oligometastatic MM patients in addition to surgery and ablation options.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-02-23
      DOI: 10.1016/j.adro.2017.02.003
       
  • Magnetic Resonance Imaging-Guided Re-irradiation of Recurrent and Second
           Primary Head and Neck Cancer

    • Authors: Allen M. Chen; Minsong Cao, Sophia Hsu, James Lamb, Argin Mikaeilian, Yingli Yang, Nzhde Agazaryan, Daniel A. Low, Michael L. Steinberg
      Abstract: Magnetic resonance imaging (MRI)-guided intensity-modulated radiotherapy (IMRT) is a relatively novel technique that has the potential to improve the therapeutic ratio for tumors of the head and neck due to its superior ability to visualize soft tissue compared to the computed tomography (CT)-based image-guided platforms, which have historically been used. This study reports our preliminary experience with the use of MRI-guided re-irradiation for recurrent head neck tumors.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-02-20
      DOI: 10.1016/j.adro.2017.02.002
       
  • A comparison of inter-fraction setup error, patient comfort and therapist
           

    • Authors: Eric Pei Ping Pang; Kellie Knight, Marilyn Baird, Joshua Ming Quan Loh, Adelene Hwee San Boo, Jeffrey Kit Loong Tuan
      Abstract: This study investigates the magnitude of inter-fraction setup error, level of patient comfort and radiation therapist (RT) acceptance of the immobilisation device required to implement transperineal ultrasound (TPUS) compared to the current standard immobilisation device. Inter-fraction setup shifts were compared and questionnaires were used to illicit patient and RT perceptions. The Clarity immobilisation system (CIS) was stable, reproducible and well tolerated by patients. RTs preferred the leg immobiliser (LI) over the CIS.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-02-15
      DOI: 10.1016/j.adro.2017.02.001
       
  • Pathologic Response after Neoadjuvant Chemotherapy Predicts Locoregional
           Control in Patients with Triple Negative Breast Cancer

    • Authors: Victor E. Chen; Erin F. Gillespie, Kaveh Zakeri, James D. Murphy, Catheryn M. Yashar, Sharon Lu, John P. Einck
      Abstract: The purpose of this manuscript is to describe how pathologic response after neoadjuvant chemotherapy for triple negative breast cancer impacts locoregional recurrence risk and disease-free survival in the setting of adjuvant radiation. This is a single-institution, retrospective study. We conclude that presence of residual disease in either breast or nodes is associated with significantly higher rates of locoregional failure as well as lower disease-free survival despite adjuvant radiation.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-02-07
      DOI: 10.1016/j.adro.2017.01.012
       
  • Long Term Outcomes and Toxicities of a Large Cohort of Anal Cancer
           Patients Treated with Dose Painted IMRT Per RTOG 0529

    • Authors: Devarati Mitra; Theodore S. Hong, Nora Horick, Brent Rose, Lorraine N. Drapek, Lawrence S. Blaszkowsky, Jill N. Allen, Eunice L. Kwak, Janet E. Murphy, Jeffrey W. Clark, David P. Ryan, James C. Cusack, Liliana G. Bordeianou, David L. Berger, Jennifer Y. Wo
      Abstract: RTOG 0529 was a phase 2 study of 52 anal cancer patients prospectively treated with dose-painted intensity modulated radiation therapy. The current study of 99 patients at a single institution with a median 49 month follow-up is the largest-to-date analysis of survival, recurrence, colostomy rates and acute as well as late toxicity treated using this standardized approach. Overall this study shows long term outcomes and tolerability are excellent.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-02-06
      DOI: 10.1016/j.adro.2017.01.009
       
  • Functional Image-Guided Radiotherapy Planning in Volumetric Modulated Arc
           Therapy for Patients with Malignant Pleural Mesothelioma

    • Authors: Yoshiko Doi; Tomoki Kimura, Takeo Nakashima, Yuki Takeuchi, Ippei Takahashi, Ikuno Nishibuchi, Yuji Murakami, Yasushi Nagata
      Abstract: We evaluated the possibility of incorporating functional lung image-derived low-attenuation area based on four-dimensional computed tomography into volumetric modulated arc therapy following extrapleural pneumonectomy in patients with malignant pleural mesothelioma. V5, V10, and the mean lung irradiation dose of the functional and contralateral lung were significantly reduced with the functional image-guided plan, and there were no major changes in PTV coverage or increases in organ-at-risk doses.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-02-01
      DOI: 10.1016/j.adro.2017.01.011
       
  • Comparison of Height and Weight After 12 vs. 18 Gy Cranial Radiotherapy in
           Pediatric Acute Lymphoblastic Leukemia (ALL) Patients

    • Authors: Albert C. Chen; M. Fatih Okcu, ZoAnn E. Dreyer, Kala Y. Kamdar, Rona Y. Sonabend, Hilary S. Suzawa, Eunji Jo, Arnold C. Paulino
      Abstract: Cranial radiotherapy (RT) prevents and controls disease in the central nervous system of acute lymphoblastic leukemia (ALL) patients but causes long term side effects, especially growth abnormalities. Prior studies of children receiving 18 Gy have shown significant height impairment, but the effect of 12 Gy on height and weight indices is unknown. This study focuses on ALL patients treated with either 12 or 18 Gy cranial RT and followed in the long term survivors’ clinic.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-01-31
      DOI: 10.1016/j.adro.2017.01.010
       
  • The Relationship Between Cardiac Radiation Dose and Mediastinal Lymph Node
           Involvement in Stage III Non-Small Cell Lung Cancer Patients

    • Authors: Laura K. McNew; Stephen R. Bowen, Olga Gopan, Matthew J. Nyflot, Shilpen A. Patel, Jing Zeng, Ramesh Rengan
      Abstract: The intention of this study was to establish a relationship between mediastinal lymph node involvement and heart dose in patients treated with definitive radiotherapy for stage III non-small cell lung cancer. In our cohort of patients, were able to show that heart dose was correlated with both multi-station nodal involvement and subcarinal nodal involvement, and therefore may be a surrogate for extent of nodal involvement rather than an independent predictor of survival.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-01-31
      DOI: 10.1016/j.adro.2017.01.008
       
  • A rare case of appendicular skeleton localization in a patient with
           Chronic Lymphocytic Leukemia (CLL) successfully treated with salvage
           radiotherapy

    • Authors: Carmelo Tuscano; Iolanda Donatella Vincelli, Demetrio Arico’, Anna Maria Marchione, Paolo Versace, Caterina Stelitano, Giuseppe Sceni, Francesca Ronco, Elvio Grazioso Russi, Said Al Sayyad
      Abstract: Bone involvments by Chronic Lymphocytic Leukemia (CLL) are considered rare events and English Medical Literature describes them only in sporadic case reports. Consequently robust indications for a rational clinical management are lacking. We report the case of a middle age man in clinical follow-up for a CLL who complained about a Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) refractory pain at right tibial level and an acute episode of anemia. Instrumental exams and a bioptic sample surprisingly demonstrated a bone tibial localization by CLL.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-01-24
      DOI: 10.1016/j.adro.2017.01.007
       
  • Impact of prone versus supine positioning on small bowel dose with pelvic
           IMRT

    • Authors: Victor J. Gonzalez; Craig R. Hullett, Lindsay Burt, Prema Rassiah-Szegedi, Vikren Sarkar, Jonathan D. Tward, Lisa J. Hazard, Y. Jessica Huang, Bill J. Salter, David K. Gaffney
      Abstract: To evaluate whether the dosimetric advantage of prone positioning with IMRT is maintained throughout the entire treatment course, we conducted a prospective study in which 10 patients had prone and supine plans generated. Patients were re-scanned weekly in both positions and “delivered” doses were re-calculated for each fraction. We conclude that prone positioning with a belly-board may provide superior small bowel sparing to supine IMRT with similar interfraction dose variation to supine treatment.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-01-23
      DOI: 10.1016/j.adro.2017.01.005
       
  • Importance of baseline PET/CT imaging on radiation field design and
           relapse rates in patients with Hodgkin Lymphoma

    • Authors: Nick Figura; Stella Flampouri, Nancy P. Mendenhall, Christopher G. Morris, Barry McCook, Savas Ozdemir, William Slayton, Eric Sandler, Bradford S. Hoppe
      Abstract: The present study evaluated 37 patients with stage I or II Hodgkin lymphoma (HL) in order to understand the impact positron emission tomography–computed tomography (PET/CT) scans had on involved site radiotherapy (ISRT) field design and pattern of relapse among HL patients. These patients received first-line chemotherapy followed by consolidative involved site radiotherapy (ISRT) to all initial sites of disease. The study found that patients with stage I/II HL receiving ISRT without pretreatment PET-CT scans appear to have an increased risk for relapse in adjacent nodal stations just outside the radiation field.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-01-17
      DOI: 10.1016/j.adro.2017.01.006
       
  • Sociodemographic Disparities in the Utilization of Proton Therapy for
           Prostate Cancer at an Urban, Academic Center

    • Authors: Kristina D. Woodhouse; Wei-Ting Hwang, Neha Vapiwala, Akansha Jain, Xingmei Wang, Stefan Both, Meera Shah, Marquise Frazier, Peter Gabriel, John P. Christodouleas, Zelig Tochner, Curtiland Deville
      Abstract: In this study, we examined whether disparities exist in proton therapy utilization in low and intermediate risk prostate cancer patients at a single academic, urban institution and found on multivariable analysis that only demographic characteristics, such as race and distance residing from the facility, as well as treatment physician and year, remained associated with proton therapy utilization, while clinical characteristics did not.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-01-17
      DOI: 10.1016/j.adro.2017.01.004
       
  • Characterization of Efficacy and Toxicity Following High-Dose Pelvic
           Re-Irradiation with Palliative Intent for Genitourinary Second Malignant
           Neoplasms or Local Recurrences after Full-Dose Radiotherapy in the Pelvis:
           A High-Volume Cancer Center Experience

    • Authors: Sophia C. Kamran; Lauren C. Harshman, Mandar S. Bhagwat, Vinayak Muralidhar, Paul L. Nguyen, Neil E. Martin, Stephanie La Follette, Sarah Faso, Akila N. Viswanathan, Jason A. Efstathiou, Clair J. Beard
      Abstract: This study assesses outcomes of 28 patients who presented with either a second malignant genitourinary malignancy or a local recurrence after radical pelvic radiotherapy for a primary malignancy. All had advanced, symptomatic, inoperable bulky disease refractory to systemic therapy and/or narcotics and thus received high dose re-irradiation (re-RT) for palliation of either pain or bleeding. Re-RT was well tolerated with minor short-term toxicity and 92% control of symptoms, which was durable in 67% of patients.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-01-16
      DOI: 10.1016/j.adro.2017.01.001
       
  • Serum Lipidomic study reveals potential early biomarkers for predicting
           response to chemoradiotherapy in advanced rectal cancer: a pilot study

    • Authors: Piero Del Boccio; Francesca Perrotti, Claudia Rossi, Ilaria Cicalini, Sara Di Santo, Mirco Zucchelli, Paolo Sacchetta, Domenico Genovesi, Damiana Pieragostino
      Abstract: This study aims to highlight a typical lipid signature able to predict the tumor response to preoperative chemoradiotherapy in advanced rectal cancer, by using a Lipidomics approach. Five lipids were validated as biomarkers able to predict response before treatment, resulting in a ROC curve characterized by an (area under the curve) AUC of 0.95. Results suggest as serum lipids could represent an useful tool in prediction of CRT response, towards a personalized treatment.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-01-05
      DOI: 10.1016/j.adro.2016.12.005
       
  • Lessons learned from re-irradiation of recurrent skull base meningioma: A
           case report and review of the literature

    • Authors: Andrew G. Pritchard; Timothy K. Nguyen, Glenn S. Bauman
      First page: 1
      Abstract: We present a case of a recurrent skull base meningioma following resection and salvage radiotherapy that highlights dose considerations and a unique pattern of recurrence, underscoring the importance of understanding regions at risk for recurrence during initial treatment planning.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-01-17
      DOI: 10.1016/j.adro.2017.01.002
       
  • A Formal Assessment of the Dosimetric Advantages of Intensity-Modulated
           Radiation Therapy in Locally-Advanced Lung Cancer

    • Authors: John Boyle; Brad Ackerson, Lin Gu, Chris R. Kelsey
      First page: 6
      Abstract: The purpose of this study was to compare normal tissue dosimetry between 3D conformal (3D-CRT) and intensity-modulated radiation therapy (IMRT) plans in patients with locally advanced lung cancer. Twenty-four patients enrolled on a prospective phase I study employing IMRT had 3D-CRT plans generated for comparison, with all plans normalized for target coverage. It was found that IMRT plans resulted in statistically and clinically significant improvements in doses to the lungs, heart, and esophagus.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-01-03
      DOI: 10.1016/j.adro.2016.12.006
       
  • Re-irradiation with Stereotactic Body Radiation Therapy After Prior
           Conventional Fractionation Radiation for Locally Recurrent Pancreatic
           Adenocarcinoma

    • Authors: Amanda J. Koong; Diego A.S. Toesca, Rie von Eyben, Erqi L. Pollom, Daniel T. Chang
      First page: 27
      Abstract: This is an institutional retrospective analysis of the use of stereotactic body radiotherapy (SBRT) for the treatment of locally recurrent pancreatic adenocarcinoma after prior conventionally fractionated chemoradiation. We demonstrate that SBRT in this setting is safe, provides good local control and symptom palliation. We recommend its use with a multi-fraction regimen.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-01-17
      DOI: 10.1016/j.adro.2017.01.003
       
  • Phase I Trial of Pre-Operative Image-Guided Intensity Modulated Proton
           Radiation Therapy (IMPT) with Simultaneously Integrated Boost to the High
           Risk Margin for Retroperitoneal Sarcomas

    • Authors: Thomas F. DeLaney; Yen-Lin Chen, Elizabeth H. Baldini, Dian Wang, Judith Adams, Shea B. Hickey, Beow Y. Yeap, Stephen M. Hahn, Karen De Amorim Bernstein, G. Petur Nielsen, Edwin Choy, John T. Mullen, Sam S. Yoon
      First page: 85
      Abstract: Selective preoperative IMRT dose escalation to the posterior retroperitoneal volume predicted to be at high risk for positive margins has been investigated as a strategy to reduce the high local recurrence rate (∼50%) after preoperative radiation and surgery for retroperitoneal sarcoma. This prospective, phase 1 study reports further dose escalation to a planned target dose of 63 GyRBE in 28 fractions to this volume with intensity modulated, magnetically scanned protons (IMPT).
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-01-03
      DOI: 10.1016/j.adro.2016.12.003
       
  • Palliative radiotherapy for SVC syndrome in metastatic Wilms tumor using
           10XFFF and 3D surface imaging to avoid anesthesia in a pediatric patient
           – A Teaching Case

    • Authors: Jean-Claude M. Rwigema; Kelly Lamiman, Robert S. Reznik, Nicole J.H. Lee, Arthur Olch, Kenneth K. Wong
      First page: 101
      Abstract: Superior vena syndrome (SVCS) may be caused by malignant diseases, with an incidence ranging from 0-30%, and can be a presenting finding or occur at disease recurrence.1,2 Leading etiologies include lymphomas, germ cell tumors, rhabdomyosarcoma, Ewing’s sarcoma, or neuroblastoma. Depending upon symptom severity and underlying malignancy, treatment options include supportive care, chemotherapy, surgical resection, and radiotherapy.3 Wilms tumor is the most common pediatric renal malignancy and is known to metastasize to the lungs, lymph nodes, liver, and bone marrow.
      Citation: Advances in Radiation Oncology (2017)
      PubDate: 2017-01-06
      DOI: 10.1016/j.adro.2016.12.007
       
  • Predictors of relapse and evaluation of the role of post-operative
           radiotherapy in a modern series of patients with surgically resected stage
           III (N2) non-small cell lung cancer

    • Authors: William G. Breen; Kenneth W. Merrell, Aaron S. Mansfield, Dennis A. Wigle, Yolanda I. Garces, Sean S. Park, Kenneth R. Olivier, Christopher L. Hallemeier
      First page: 12
      Abstract: We retrospectively examined outcomes in patients with stage III (N2) NSCLC who underwent curative-intent resection at our institution and received POCT and/or PORT. Patients who received PORT (versus no PORT) had a lower risk of LRR and a higher OS, although these differences were not statistically significant. We did not observe any life-threatening or fatal AEs related to PORT.
      Citation: Advances in Radiation Oncology (2016)
      PubDate: 2016-12-21
      DOI: 10.1016/j.adro.2016.12.004
       
  • The Effect of Variations in Atelectasis on Tumor Displacement During
           Radiation Therapy for Locally Advanced Lung Cancer

    • Authors: Nathan Tennyson; Elisabeth Weiss, William Sleeman, Mihaela Rosu, Nuzhat Jan, Geoffrey D. Hugo
      First page: 19
      Abstract: This study analyzed 12 patients with atelectasis and 10 without atelectasis who underwent repeat 4D fan beam CT during the radiotherapy course. Patients with atelectasis had significantly greater tumor displacements than patients without atelectasis, and these tumor displacements often exceeded standard setup margins. Patients with atelectasis might benefit from repeated 3D imaging during radiotherapy and possible replanning for large tumor displacements.
      Citation: Advances in Radiation Oncology (2016)
      PubDate: 2016-12-12
      DOI: 10.1016/j.adro.2016.12.001
       
  • Independent test of a model to predictive severe acute esophagitis

    • Authors: Ellen X. Huang; Clifford G. Robinson, Alerson Molotievschi, Jeffrey D. Bradley, Joseph O. Deasy, Jung Hun Oh
      First page: 37
      Abstract: Treatment planning factors are known to affect the risk of severe acute esophagitis during thoracic radiotherapy. We tested a previously published model (a logistic function with a combination of mean esophageal dose and the use of concurrent chemotherapy) to predict the risk of severe acute esophagitis on an independent dataset. Its predictive performance was nearly as good as the best logistic model, consisting of the same two variables found previously, derived from the new dataset.
      Citation: Advances in Radiation Oncology (2016)
      PubDate: 2016-11-16
      DOI: 10.1016/j.adro.2016.11.003
       
  • Analysis of Patient Outcomes Following Proton Radiotherapy for
           Retinoblastoma

    • Authors: Kent W. Mouw; Beow Y. Yeap, Paul Caruso, Aaron Fay, Madhusmita Misra, Roshan V. Sethi, Shannon M. MacDonald, Yen-Lin Chen, Nancy J. Tarbell, Torunn I. Yock, Suzanne K. Freitag, John E. Munzenrider, Eric Grabowski, Michelle Katz, Karen Kuhlthau, Dawn DeCastro, Gena Heidary, Jessica Ciralsky, Shizuo Mukai, Helen A. Shih
      First page: 44
      Abstract: Prospective analyses of patient outcomes following proton radiotherapy (PRT) for retinoblastoma (RB) are needed to understand the long-term outcomes of treatment. We invited RB patients previously treated with PRT at our institution to return for comprehensive analysis of visual, endocrine, cosmetic, and parent and family quality-of-life outcomes. We find that in addition to providing an opportunity for long-term disease control, PRT appears to be associated with few late effects in this cohort.
      Citation: Advances in Radiation Oncology (2016)
      PubDate: 2016-11-23
      DOI: 10.1016/j.adro.2016.11.002
       
  • Limited short-term effect of palliative radiotherapy on Quantitative
           Computed Tomography-derived bone mineral density in femora with metastases
           

    • Authors: Florieke Eggermont; Loes C. Derikx, Nico Verdonschot, Gerjon Hannink, Robert S.J.P. Kaatee, Esther Tanck, Yvette M. van der Linden
      First page: 53
      Abstract: The effect of palliative radiotherapy on bone mineral density (BMD) of femoral bone metastases and surrounding bone was studied in 42 patients using quantitative CT scans. Ten weeks after treatment, no difference in BMD was seen between patients treated with single or multiple fractions. BMD did not change in lytic lesions, but increased slightly in mixed and blastic lesions over time.
      Citation: Advances in Radiation Oncology (2016)
      PubDate: 2016-11-09
      DOI: 10.1016/j.adro.2016.11.001
       
  • ACR Appropriateness Criteria® External beam Radiation Therapy treatment
           planning for Clinically localized Prostate Cancer, Part I of II

    • Authors: Expert Panel on Radiation Oncology–Prostate; Nicholas G. Zaorsky, Timothy N. Showalter, Gary A. Ezzell, Paul L. Nguyen, Dean G. Assimos, Anthony V. D'Amico, Alexander R. Gottschalk, Gary S. Gustafson, Sameer R. Keole, Stanley L. Liauw, Shane Lloyd, Patrick W. McLaughlin, Benjamin Movsas, Bradley R. Prestidge, Al V. Taira, Neha Vapiwala, Brian J. Davis
      First page: 62
      Abstract: Prostate cancer is the most common cancer among men in the United States, with an estimated 220,800 new diagnoses in 2015 [1]. External-beam radiation therapy (EBRT) is the treatment of choice for many men with localized prostate cancer [2]. It is generally accepted that EBRT is a first-line treatment option for localized prostate cancer, as are radical prostatectomy and brachytherapy [3-6]. Advances in image-based EBRT treatment planning and localization have contributed to better targeting of the prostate and greater sparing of normal tissues, permitting dose escalation while maintaining safe doses to adjacent normal tissues.
      Citation: Advances in Radiation Oncology (2016)
      PubDate: 2016-10-20
       
  • Impact of moving target on measurement accuracy in 3D and 4D PET imaging
           – a phantom study

    • Authors: Yunfeng Cui; James Bowsher, Jing Cai, Fang-Fang Yin
      First page: 94
      Abstract: This study conducted phantom experiments to evaluate the uncertainties in quantitative measurements of moving targets from PET imaging. The study also investigated how much the measurement accuracy can be improved with 4D PET imaging with different reconstruction approaches. The results of this study provide a quantitative basis for radiation oncology professionals for their decision making when imaging a moving tumor with PET.
      Citation: Advances in Radiation Oncology (2016)
      PubDate: 2016-12-12
      DOI: 10.1016/j.adro.2016.12.002
       
 
 
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