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Publisher: Elsevier   (Total: 3163 journals)

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Showing 1 - 200 of 3163 Journals sorted alphabetically
A Practical Logic of Cognitive Systems     Full-text available via subscription   (Followers: 9)
AASRI Procedia     Open Access   (Followers: 15)
Academic Pediatrics     Hybrid Journal   (Followers: 33, SJR: 1.655, CiteScore: 2)
Academic Radiology     Hybrid Journal   (Followers: 23, SJR: 1.015, CiteScore: 2)
Accident Analysis & Prevention     Partially Free   (Followers: 95, SJR: 1.462, CiteScore: 3)
Accounting Forum     Hybrid Journal   (Followers: 25, SJR: 0.932, CiteScore: 2)
Accounting, Organizations and Society     Hybrid Journal   (Followers: 36, SJR: 1.771, CiteScore: 3)
Achievements in the Life Sciences     Open Access   (Followers: 5)
Acta Anaesthesiologica Taiwanica     Open Access   (Followers: 7)
Acta Astronautica     Hybrid Journal   (Followers: 413, SJR: 0.758, CiteScore: 2)
Acta Automatica Sinica     Full-text available via subscription   (Followers: 2)
Acta Biomaterialia     Hybrid Journal   (Followers: 27, SJR: 1.967, CiteScore: 7)
Acta Colombiana de Cuidado Intensivo     Full-text available via subscription   (Followers: 2)
Acta de Investigación Psicológica     Open Access   (Followers: 3)
Acta Ecologica Sinica     Open Access   (Followers: 10, SJR: 0.18, CiteScore: 1)
Acta Haematologica Polonica     Free   (Followers: 1, SJR: 0.128, CiteScore: 0)
Acta Histochemica     Hybrid Journal   (Followers: 3, SJR: 0.661, CiteScore: 2)
Acta Materialia     Hybrid Journal   (Followers: 250, SJR: 3.263, CiteScore: 6)
Acta Mathematica Scientia     Full-text available via subscription   (Followers: 5, SJR: 0.504, CiteScore: 1)
Acta Mechanica Solida Sinica     Full-text available via subscription   (Followers: 9, SJR: 0.542, CiteScore: 1)
Acta Oecologica     Hybrid Journal   (Followers: 12, SJR: 0.834, CiteScore: 2)
Acta Otorrinolaringologica (English Edition)     Full-text available via subscription  
Acta Otorrinolaringológica Española     Full-text available via subscription   (Followers: 2, SJR: 0.307, CiteScore: 0)
Acta Pharmaceutica Sinica B     Open Access   (Followers: 1, SJR: 1.793, CiteScore: 6)
Acta Poética     Open Access   (Followers: 4, SJR: 0.101, CiteScore: 0)
Acta Psychologica     Hybrid Journal   (Followers: 27, SJR: 1.331, CiteScore: 2)
Acta Sociológica     Open Access   (Followers: 1)
Acta Tropica     Hybrid Journal   (Followers: 6, SJR: 1.052, CiteScore: 2)
Acta Urológica Portuguesa     Open Access  
Actas Dermo-Sifiliograficas     Full-text available via subscription   (Followers: 3, SJR: 0.374, CiteScore: 1)
Actas Dermo-Sifiliográficas (English Edition)     Full-text available via subscription   (Followers: 2)
Actas Urológicas Españolas     Full-text available via subscription   (Followers: 3, SJR: 0.344, CiteScore: 1)
Actas Urológicas Españolas (English Edition)     Full-text available via subscription   (Followers: 1)
Actualites Pharmaceutiques     Full-text available via subscription   (Followers: 6, SJR: 0.19, CiteScore: 0)
Actualites Pharmaceutiques Hospitalieres     Full-text available via subscription   (Followers: 3)
Acupuncture and Related Therapies     Hybrid Journal   (Followers: 6)
Acute Pain     Full-text available via subscription   (Followers: 14, SJR: 2.671, CiteScore: 5)
Ad Hoc Networks     Hybrid Journal   (Followers: 11, SJR: 0.53, CiteScore: 4)
Addictive Behaviors     Hybrid Journal   (Followers: 16, SJR: 1.29, CiteScore: 3)
Addictive Behaviors Reports     Open Access   (Followers: 8, SJR: 0.755, CiteScore: 2)
Additive Manufacturing     Hybrid Journal   (Followers: 9, SJR: 2.611, CiteScore: 8)
Additives for Polymers     Full-text available via subscription   (Followers: 22)
Advanced Drug Delivery Reviews     Hybrid Journal   (Followers: 151, SJR: 4.09, CiteScore: 13)
Advanced Engineering Informatics     Hybrid Journal   (Followers: 11, SJR: 1.167, CiteScore: 4)
Advanced Powder Technology     Hybrid Journal   (Followers: 17, SJR: 0.694, CiteScore: 3)
Advances in Accounting     Hybrid Journal   (Followers: 8, SJR: 0.277, CiteScore: 1)
Advances in Agronomy     Full-text available via subscription   (Followers: 12, SJR: 2.384, CiteScore: 5)
Advances in Anesthesia     Full-text available via subscription   (Followers: 28, SJR: 0.126, CiteScore: 0)
Advances in Antiviral Drug Design     Full-text available via subscription   (Followers: 2)
Advances in Applied Mathematics     Full-text available via subscription   (Followers: 10, SJR: 0.992, CiteScore: 1)
Advances in Applied Mechanics     Full-text available via subscription   (Followers: 11, SJR: 1.551, CiteScore: 4)
Advances in Applied Microbiology     Full-text available via subscription   (Followers: 23, SJR: 2.089, CiteScore: 5)
Advances In Atomic, Molecular, and Optical Physics     Full-text available via subscription   (Followers: 14, SJR: 0.572, CiteScore: 2)
Advances in Biological Regulation     Hybrid Journal   (Followers: 4, SJR: 2.61, CiteScore: 7)
Advances in Botanical Research     Full-text available via subscription   (Followers: 2, SJR: 0.686, CiteScore: 2)
Advances in Cancer Research     Full-text available via subscription   (Followers: 32, SJR: 3.043, CiteScore: 6)
Advances in Carbohydrate Chemistry and Biochemistry     Full-text available via subscription   (Followers: 8, SJR: 1.453, CiteScore: 2)
Advances in Catalysis     Full-text available via subscription   (Followers: 5, SJR: 1.992, CiteScore: 5)
Advances in Cell Aging and Gerontology     Full-text available via subscription   (Followers: 3)
Advances in Cellular and Molecular Biology of Membranes and Organelles     Full-text available via subscription   (Followers: 12)
Advances in Chemical Engineering     Full-text available via subscription   (Followers: 27, SJR: 0.156, CiteScore: 1)
Advances in Child Development and Behavior     Full-text available via subscription   (Followers: 10, SJR: 0.713, CiteScore: 1)
Advances in Chronic Kidney Disease     Full-text available via subscription   (Followers: 10, SJR: 1.316, CiteScore: 2)
Advances in Clinical Chemistry     Full-text available via subscription   (Followers: 29, SJR: 1.562, CiteScore: 3)
Advances in Colloid and Interface Science     Full-text available via subscription   (Followers: 19, SJR: 1.977, CiteScore: 8)
Advances in Computers     Full-text available via subscription   (Followers: 14, SJR: 0.205, CiteScore: 1)
Advances in Dermatology     Full-text available via subscription   (Followers: 15)
Advances in Developmental Biology     Full-text available via subscription   (Followers: 12)
Advances in Digestive Medicine     Open Access   (Followers: 9)
Advances in DNA Sequence-Specific Agents     Full-text available via subscription   (Followers: 5)
Advances in Drug Research     Full-text available via subscription   (Followers: 24)
Advances in Ecological Research     Full-text available via subscription   (Followers: 44, SJR: 2.524, CiteScore: 4)
Advances in Engineering Software     Hybrid Journal   (Followers: 28, SJR: 1.159, CiteScore: 4)
Advances in Experimental Biology     Full-text available via subscription   (Followers: 7)
Advances in Experimental Social Psychology     Full-text available via subscription   (Followers: 44, SJR: 5.39, CiteScore: 8)
Advances in Exploration Geophysics     Full-text available via subscription   (Followers: 1)
Advances in Fluorine Science     Full-text available via subscription   (Followers: 9)
Advances in Food and Nutrition Research     Full-text available via subscription   (Followers: 58, SJR: 0.591, CiteScore: 2)
Advances in Fuel Cells     Full-text available via subscription   (Followers: 16)
Advances in Genetics     Full-text available via subscription   (Followers: 16, SJR: 1.354, CiteScore: 4)
Advances in Genome Biology     Full-text available via subscription   (Followers: 8, SJR: 12.74, CiteScore: 13)
Advances in Geophysics     Full-text available via subscription   (Followers: 6, SJR: 1.193, CiteScore: 3)
Advances in Heat Transfer     Full-text available via subscription   (Followers: 21, SJR: 0.368, CiteScore: 1)
Advances in Heterocyclic Chemistry     Full-text available via subscription   (Followers: 12, SJR: 0.749, CiteScore: 3)
Advances in Human Factors/Ergonomics     Full-text available via subscription   (Followers: 22)
Advances in Imaging and Electron Physics     Full-text available via subscription   (Followers: 2, SJR: 0.193, CiteScore: 0)
Advances in Immunology     Full-text available via subscription   (Followers: 36, SJR: 4.433, CiteScore: 6)
Advances in Inorganic Chemistry     Full-text available via subscription   (Followers: 8, SJR: 1.163, CiteScore: 2)
Advances in Insect Physiology     Full-text available via subscription   (Followers: 2, SJR: 1.938, CiteScore: 3)
Advances in Integrative Medicine     Hybrid Journal   (Followers: 6, SJR: 0.176, CiteScore: 0)
Advances in Intl. Accounting     Full-text available via subscription   (Followers: 3)
Advances in Life Course Research     Hybrid Journal   (Followers: 8, SJR: 0.682, CiteScore: 2)
Advances in Lipobiology     Full-text available via subscription   (Followers: 1)
Advances in Magnetic and Optical Resonance     Full-text available via subscription   (Followers: 9)
Advances in Marine Biology     Full-text available via subscription   (Followers: 18, SJR: 0.88, CiteScore: 2)
Advances in Mathematics     Full-text available via subscription   (Followers: 11, SJR: 3.027, CiteScore: 2)
Advances in Medical Sciences     Hybrid Journal   (Followers: 6, SJR: 0.694, CiteScore: 2)
Advances in Medicinal Chemistry     Full-text available via subscription   (Followers: 5)
Advances in Microbial Physiology     Full-text available via subscription   (Followers: 4, SJR: 1.158, CiteScore: 3)
Advances in Molecular and Cell Biology     Full-text available via subscription   (Followers: 22)
Advances in Molecular and Cellular Endocrinology     Full-text available via subscription   (Followers: 8)
Advances in Molecular Toxicology     Full-text available via subscription   (Followers: 7, SJR: 0.182, CiteScore: 0)
Advances in Nanoporous Materials     Full-text available via subscription   (Followers: 3)
Advances in Oncobiology     Full-text available via subscription   (Followers: 1)
Advances in Organ Biology     Full-text available via subscription   (Followers: 1)
Advances in Organometallic Chemistry     Full-text available via subscription   (Followers: 17, SJR: 1.875, CiteScore: 4)
Advances in Parallel Computing     Full-text available via subscription   (Followers: 7, SJR: 0.174, CiteScore: 0)
Advances in Parasitology     Full-text available via subscription   (Followers: 5, SJR: 1.579, CiteScore: 4)
Advances in Pediatrics     Full-text available via subscription   (Followers: 24, SJR: 0.461, CiteScore: 1)
Advances in Pharmaceutical Sciences     Full-text available via subscription   (Followers: 11)
Advances in Pharmacology     Full-text available via subscription   (Followers: 16, SJR: 1.536, CiteScore: 3)
Advances in Physical Organic Chemistry     Full-text available via subscription   (Followers: 8, SJR: 0.574, CiteScore: 1)
Advances in Phytomedicine     Full-text available via subscription  
Advances in Planar Lipid Bilayers and Liposomes     Full-text available via subscription   (Followers: 3, SJR: 0.109, CiteScore: 1)
Advances in Plant Biochemistry and Molecular Biology     Full-text available via subscription   (Followers: 9)
Advances in Plant Pathology     Full-text available via subscription   (Followers: 5)
Advances in Porous Media     Full-text available via subscription   (Followers: 5)
Advances in Protein Chemistry     Full-text available via subscription   (Followers: 18)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 20, SJR: 0.791, CiteScore: 2)
Advances in Psychology     Full-text available via subscription   (Followers: 63)
Advances in Quantum Chemistry     Full-text available via subscription   (Followers: 6, SJR: 0.371, CiteScore: 1)
Advances in Radiation Oncology     Open Access   (Followers: 1, SJR: 0.263, CiteScore: 1)
Advances in Small Animal Medicine and Surgery     Hybrid Journal   (Followers: 3, SJR: 0.101, CiteScore: 0)
Advances in Space Biology and Medicine     Full-text available via subscription   (Followers: 6)
Advances in Space Research     Full-text available via subscription   (Followers: 395, SJR: 0.569, CiteScore: 2)
Advances in Structural Biology     Full-text available via subscription   (Followers: 5)
Advances in Surgery     Full-text available via subscription   (Followers: 10, SJR: 0.555, CiteScore: 2)
Advances in the Study of Behavior     Full-text available via subscription   (Followers: 33, SJR: 2.208, CiteScore: 4)
Advances in Veterinary Medicine     Full-text available via subscription   (Followers: 17)
Advances in Veterinary Science and Comparative Medicine     Full-text available via subscription   (Followers: 13)
Advances in Virus Research     Full-text available via subscription   (Followers: 5, SJR: 2.262, CiteScore: 5)
Advances in Water Resources     Hybrid Journal   (Followers: 47, SJR: 1.551, CiteScore: 3)
Aeolian Research     Hybrid Journal   (Followers: 6, SJR: 1.117, CiteScore: 3)
Aerospace Science and Technology     Hybrid Journal   (Followers: 341, SJR: 0.796, CiteScore: 3)
AEU - Intl. J. of Electronics and Communications     Hybrid Journal   (Followers: 8, SJR: 0.42, CiteScore: 2)
African J. of Emergency Medicine     Open Access   (Followers: 6, SJR: 0.296, CiteScore: 0)
Ageing Research Reviews     Hybrid Journal   (Followers: 11, SJR: 3.671, CiteScore: 9)
Aggression and Violent Behavior     Hybrid Journal   (Followers: 449, SJR: 1.238, CiteScore: 3)
Agri Gene     Hybrid Journal   (Followers: 1, SJR: 0.13, CiteScore: 0)
Agricultural and Forest Meteorology     Hybrid Journal   (Followers: 17, SJR: 1.818, CiteScore: 5)
Agricultural Systems     Hybrid Journal   (Followers: 31, SJR: 1.156, CiteScore: 4)
Agricultural Water Management     Hybrid Journal   (Followers: 42, SJR: 1.272, CiteScore: 3)
Agriculture and Agricultural Science Procedia     Open Access   (Followers: 3)
Agriculture and Natural Resources     Open Access   (Followers: 3)
Agriculture, Ecosystems & Environment     Hybrid Journal   (Followers: 57, SJR: 1.747, CiteScore: 4)
Ain Shams Engineering J.     Open Access   (Followers: 5, SJR: 0.589, CiteScore: 3)
Air Medical J.     Hybrid Journal   (Followers: 6, SJR: 0.26, CiteScore: 0)
AKCE Intl. J. of Graphs and Combinatorics     Open Access   (SJR: 0.19, CiteScore: 0)
Alcohol     Hybrid Journal   (Followers: 11, SJR: 1.153, CiteScore: 3)
Alcoholism and Drug Addiction     Open Access   (Followers: 9)
Alergologia Polska : Polish J. of Allergology     Full-text available via subscription   (Followers: 1)
Alexandria Engineering J.     Open Access   (Followers: 1, SJR: 0.604, CiteScore: 3)
Alexandria J. of Medicine     Open Access   (Followers: 1, SJR: 0.191, CiteScore: 1)
Algal Research     Partially Free   (Followers: 11, SJR: 1.142, CiteScore: 4)
Alkaloids: Chemical and Biological Perspectives     Full-text available via subscription   (Followers: 2)
Allergologia et Immunopathologia     Full-text available via subscription   (Followers: 1, SJR: 0.504, CiteScore: 1)
Allergology Intl.     Open Access   (Followers: 5, SJR: 1.148, CiteScore: 2)
Alpha Omegan     Full-text available via subscription   (SJR: 3.521, CiteScore: 6)
ALTER - European J. of Disability Research / Revue Européenne de Recherche sur le Handicap     Full-text available via subscription   (Followers: 9, SJR: 0.201, CiteScore: 1)
Alzheimer's & Dementia     Hybrid Journal   (Followers: 52, SJR: 4.66, CiteScore: 10)
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring     Open Access   (Followers: 4, SJR: 1.796, CiteScore: 4)
Alzheimer's & Dementia: Translational Research & Clinical Interventions     Open Access   (Followers: 4, SJR: 1.108, CiteScore: 3)
Ambulatory Pediatrics     Hybrid Journal   (Followers: 6)
American Heart J.     Hybrid Journal   (Followers: 50, SJR: 3.267, CiteScore: 4)
American J. of Cardiology     Hybrid Journal   (Followers: 54, SJR: 1.93, CiteScore: 3)
American J. of Emergency Medicine     Hybrid Journal   (Followers: 45, SJR: 0.604, CiteScore: 1)
American J. of Geriatric Pharmacotherapy     Full-text available via subscription   (Followers: 10)
American J. of Geriatric Psychiatry     Hybrid Journal   (Followers: 14, SJR: 1.524, CiteScore: 3)
American J. of Human Genetics     Hybrid Journal   (Followers: 34, SJR: 7.45, CiteScore: 8)
American J. of Infection Control     Hybrid Journal   (Followers: 28, SJR: 1.062, CiteScore: 2)
American J. of Kidney Diseases     Hybrid Journal   (Followers: 35, SJR: 2.973, CiteScore: 4)
American J. of Medicine     Hybrid Journal   (Followers: 46)
American J. of Medicine Supplements     Full-text available via subscription   (Followers: 3, SJR: 1.967, CiteScore: 2)
American J. of Obstetrics and Gynecology     Hybrid Journal   (Followers: 208, SJR: 2.7, CiteScore: 4)
American J. of Ophthalmology     Hybrid Journal   (Followers: 64, SJR: 3.184, CiteScore: 4)
American J. of Ophthalmology Case Reports     Open Access   (Followers: 5, SJR: 0.265, CiteScore: 0)
American J. of Orthodontics and Dentofacial Orthopedics     Full-text available via subscription   (Followers: 6, SJR: 1.289, CiteScore: 1)
American J. of Otolaryngology     Hybrid Journal   (Followers: 25, SJR: 0.59, CiteScore: 1)
American J. of Pathology     Hybrid Journal   (Followers: 28, SJR: 2.139, CiteScore: 4)
American J. of Preventive Medicine     Hybrid Journal   (Followers: 28, SJR: 2.164, CiteScore: 4)
American J. of Surgery     Hybrid Journal   (Followers: 38, SJR: 1.141, CiteScore: 2)
American J. of the Medical Sciences     Hybrid Journal   (Followers: 12, SJR: 0.767, CiteScore: 1)
Ampersand : An Intl. J. of General and Applied Linguistics     Open Access   (Followers: 7)
Anaerobe     Hybrid Journal   (Followers: 4, SJR: 1.144, CiteScore: 3)
Anaesthesia & Intensive Care Medicine     Full-text available via subscription   (Followers: 62, SJR: 0.138, CiteScore: 0)
Anaesthesia Critical Care & Pain Medicine     Full-text available via subscription   (Followers: 17, SJR: 0.411, CiteScore: 1)
Anales de Cirugia Vascular     Full-text available via subscription  
Anales de Pediatría     Full-text available via subscription   (Followers: 3, SJR: 0.277, CiteScore: 0)
Anales de Pediatría (English Edition)     Full-text available via subscription  
Anales de Pediatría Continuada     Full-text available via subscription  
Analytic Methods in Accident Research     Hybrid Journal   (Followers: 5, SJR: 4.849, CiteScore: 10)
Analytica Chimica Acta     Hybrid Journal   (Followers: 42, SJR: 1.512, CiteScore: 5)
Analytical Biochemistry     Hybrid Journal   (Followers: 173, SJR: 0.633, CiteScore: 2)
Analytical Chemistry Research     Open Access   (Followers: 11, SJR: 0.411, CiteScore: 2)
Analytical Spectroscopy Library     Full-text available via subscription   (Followers: 11)
Anesthésie & Réanimation     Full-text available via subscription   (Followers: 2)
Anesthesiology Clinics     Full-text available via subscription   (Followers: 23, SJR: 0.683, CiteScore: 2)
Angiología     Full-text available via subscription   (SJR: 0.121, CiteScore: 0)
Angiologia e Cirurgia Vascular     Open Access   (Followers: 1, SJR: 0.111, CiteScore: 0)
Animal Behaviour     Hybrid Journal   (Followers: 193, SJR: 1.58, CiteScore: 3)

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Journal Cover
Advances in Integrative Medicine
Journal Prestige (SJR): 0.176
Number of Followers: 6  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Online) 2212-9588
Published by Elsevier Homepage  [3163 journals]
  • Integrative medicine and primary care: Moving forward or moving
           backwards'
    • Abstract: Publication date: December 2018Source: Advances in Integrative Medicine, Volume 5, Issue 3Author(s): Jon Wardle
       
  • Peter Fisher
    • Abstract: Publication date: December 2018Source: Advances in Integrative Medicine, Volume 5, Issue 3Author(s):
       
  • A Narrative study about the role of Viola odorata as traditional medicinal
           plant in management of respiratory problems
    • Abstract: Publication date: December 2018Source: Advances in Integrative Medicine, Volume 5, Issue 3Author(s): Mohaddese Mahboubi, Leila Mohammad Taghizadeh Kashani ObjectiveViola odorata as medicinal plant is used as poultice for treatment of headache, cough, colds, bronchitis, and fever in different Traditional medicines. To ascertain the extent of knowledge around its traditional use, the efficacy of V. odorata was evaluated in management of respiratory ailments as antitussive, febrifuge, analgesic, anti-inflammatory and anti-infectious agents.MethodsTraditional and modern information about V. odorata use in cough, colds, bronchitis, fever as well as V. odorata’s effects on clinical symptoms of respiratory problems was sourced from scientific databases and traditional resources.ResultsV. odorata appears to be well known in several medicinal systems (Iranian, Greco-Arab, Ayurvedic and Unani) for treatment of whooping cough, headaches, migraine, insomnia, sore throat and epilepsy in children and adults. Modern clinical studies appear to confirm the efficacy of V. odorata syrup in cough, insomnia and migraine observed in traditional studies. V. odorata (as a syrup) appears to be a safe treatment for management of respiratory ailments in children. The efficacy of V. odorata in treatment of pain, fever, cough, infection and inflammation may make it a suitable treatment for respiratory ailments.ConclusionLarger clinical studies are required to confirm the effectiveness of V. odorata as an acceptable treatment for respiratory related problems in children and adults.
       
  • Coming to terms with evidence: ‘What is appropriate evidence in
           integrative medicine practice'
    • Abstract: Publication date: December 2018Source: Advances in Integrative Medicine, Volume 5, Issue 3Author(s): Joanna E. Harnett, Stephen P. Myers
       
  • A pilot trial examining the absorption of oral forms of folate
           supplementation in a healthy population: A randomised control trial
    • Abstract: Publication date: Available online 20 September 2018Source: Advances in Integrative MedicineAuthor(s): Jessica Bayes, Nitish Agrawal, Janet Schloss Background & AimsFolate supplements are commonly prescribed by health professionals for a number of different conditions, however, the absorption of the different derivatives remains unclear. This pilot trial aims to assess the absorption of various forms of folate supplements in a healthy populationMethodsA four-week, single blinded, randomised control trial was conducted on 30 healthy individuals. The intervention included supplementation with 500mcg of either folic acid, folinic acid or 5-Methyltetrahydrofolate (5-MTHF). Fifteen participants were allocated to the intervention and fifteen to the control group for comparison. At baseline (week 0) a case report was completed and pathology tests for serum folate, B12 and MTHFR polymorphisms were conducted. Follow up serum folate blood pathology tests were assessed at week 2 and week 4 along with additional food diariesResultsOf the cohort, 87% (n = 26) were found to have a MTHFR polymorphism with both A1298C (n = 12) and C677 T (n = 18) being tested. Only13% (n = 4) of participants had no mutation. The different MTHFR mutations were observed across both the control group and all of the intervention groups. The mean (±SD) baseline folate was 33.7 nmol/L ± 7.55 (Reference range:>9.0). Participants who had both A1298C and C677 T polymorphism had lower baseline folate with a mean (±SD) of 29 nmol/L ± 8.75. During the four weeks an overall increase in mean serum folate was observed in both the folinic acid and 5-MTHF group. The folinic acid intervention saw a mean (±SD) increase of 15.3 nmol/L ± 3.56 and 5-MTHF saw a mean (±SD) increase of 9.1 nmol/L ± 1.67, however a decrease in mean serum folate was detected in the folic acid group. In the folinic acid and 5-MTHF groups, serum folate increases were observed in individuals irrespective of their MTHFR status.ConclusionsThis research has provided a foundation for further work investigating folate absorption. The results of the trial suggest that folinic acid has the best absorption, however, it may not have the best bioavailability. More research is required for greater clarification regarding the absorption and bioavailability of these supplements.
       
  • The Effect of Stress Management on Patients with Asthma: A Randomized
           Controlled Trial
    • Abstract: Publication date: Available online 11 September 2018Source: Advances in Integrative MedicineAuthor(s): Georgia Georga, George Chrousos, Artemios Artemiadis, Pelekasis P. Panagiotis, Petros Bakakos, Christina Darviri BackgroundPrevious evidence indicates a negative influence of elevated stress on asthma symptoms and asthma-related quality of life.ObjectiveTo investigate the effects of stress management (SM; progressive muscle relaxation accompanied by biofeedback-assisted relaxation breathing),on stress levels, asthma control, asthma-related quality of life and physical exercice in patients with intermittent and mild chronic asthma.MethodsThis is a phase 2, two-armed, parallel randomized controlled trial using an intervention SM group (N = 23) and a usual care (UC) control group (N = 19). The measurements included the Perceived Stress Scale (PSS), the Asthma Control Test (ACT), the Mini Asthma Quality of Life Questionnaire (MAQLQ) and one Likert-type question measuring frequency of weekly exercise. The assessments were carried out at baseline and after 8 weeks.ResultsNo differences were noted between the two groups at baseline. At the endpoint assessment, there were statistically significant differences in favor of the intervention group in all the outcomes assessed.ConclusionsThis study showed that SM may be promising in the treatment of asthma, but this needs to be confirmed by future studies.
       
  • Purslane (Portulaca oleracea) effect on heavy menstrual bleeding
           (menorrhagia) in Iranian women
    • Abstract: Publication date: August 2018Source: Advances in Integrative Medicine, Volume 5, Issue 2Author(s): Narjes Mirzaei, Fatemeh Salehi Moghaddam, Giti Ozgoli, Shamim Sahranavard, Erfan Ghasemi IntroductionThe current study was designed to examine the effect of the herbal medicine purslane on heavy menstrual bleeding (HMB).MethodologyThis randomized double-blinded placebo-controlled clinical trial was performed on women who suffered from HMB with their regular menstrual cycles. Both groups (48 in purslane-using group and 47 in control group) received mefenamic acid every 8 h from the first day to the third day of their periods in two menstrual cycles. In the intervention group, in addition to mefenamic acid, a capsule of purslane seeds, and in the control group, a similar capsule containing corn starch with the same protocol were administered. A pictorial blood loss assessment chart (PBLAC) was used to determine bleeding.FindingsA significant difference was observed between the purslane and control groups (p 
       
  • Poor integrative medicine policy results from ignorance: But is it wilful
           or inadvertent'
    • Abstract: Publication date: August 2018Source: Advances in Integrative Medicine, Volume 5, Issue 2Author(s): Jon Wardle
       
  • Immediate effect of hot chest pack on cardio-respiratory functions in
           healthy volunteers: A randomized cross-over study
    • Abstract: Publication date: August 2018Source: Advances in Integrative Medicine, Volume 5, Issue 2Author(s): Thoudam Manjuladevi, A. Mooventhan, N.K. Manjunath BackgroundThe chest pack is one of the most common hydrotherapy procedures. Though the hot chest pack (HCP) is commonly employed by many practitioner to improve various cardio-respiratory problems, there is no scientific report validating its effect on either cardiovascular or respiratory functions. The current study has been conducted to evaluate the effect of cardio-respiratory functions in healthy volunteers.Materials and methodsThirty healthy female volunteers with the age range of 18–24 years were recruited and randomly divided into 2-groups. Subjects of both the groups underwent 20-min each of HCP (study session) and supine rest (SR - control session) sessions in 2-different orders. In the first group, 15 subjects underwent HCP on day-1 and SR on day-2, while in the second group the order of intervention was reversed. Assessments were taken before and after each session. Statistical analysis was performed using statistical package for the social sciences, version 16.ResultsA significant reduction in systolic blood pressure was observed both in study and control sessions. However, a significant reduction in diastolic blood pressure, mean arterial pressure, pulse rate, rate pressure product (RPP) and double product (Do-P), along with a significant improvement in peak expiratory flow rate, was observed only in the HCP session. Reduction in RPP and Do-P was better in the HCP session than in the control session.ConclusionResults of this study suggest that 20 min of HCP might be effective in improving cardio-respiratory functions of healthy volunteers.
       
  • The interaction of FTO-rs9939609 polymorphism with artichoke leaf extract
           effects on cardiometabolic risk factors in hypertriglyceridemia: A
           randomized clinical trial
    • Abstract: Publication date: Available online 31 August 2018Source: Advances in Integrative MedicineAuthor(s): Khatereh Rezazadeh, Mohammad Asghari-Jafarabadi, Mehranghiz Ebrahimi-Mameghani ObjectiveHypertriglyceridemia is associated with an increased risk of cardiovascular disease. The potential favorable effects of artichoke leaf extract (ALE) on anthropometric and metabolic indices may affect by fat mass and obesity associated (FTO)-rs9939609 polymorphism. This study was designed to evaluate the effects of ALE supplementation on cardiometabolic risk factors in hypertriglyceridemic patients regarding the interaction of rs9939609-FTO polymorphism with intervention outcomes.MethodsIn this double-blind placebo-controlled randomized clinical trial, 52 patients with hypertriglyceridemia randomly allocated to receive ALE (1800 mg/day as four tablets) or matching placebo (consisting of corn starch, lactose, and avicel) for 12 weeks. The measurement of anthropometric indices, fasting blood sugar (FBS), and lipid profile was performed before and after the intervention. The FTO-rs9939609 polymorphism was genotyped by polymerase chain reaction-restriction length polymorphism (PCR-RFLP). The interaction was tested using two-way ANOVA.ResultsForty-eight patients completed the trial (intervention, n = 24, placebo = 24). ALE and placebo groups were similar in the baseline characteristics. ALE supplementation did not change anthropometric indices and metabolic parameters. However, there was a significant interaction between FTO-rs9939609 polymorphism and TC, LDL-C, and TG level response to ALE supplementation. Moreover, significant changes in TG level were observed in A allele carriers compared to subjects with TT genotype.ConclusionNo significant effect of ALE supplementation was shown on anthropometric and biochemical indices in Iranian hypertriglyceridemic patients. However, rs9939609 variant of FTO gene seems to affect lipid profile response to ALE supplementation. Further clinical trials with larger sample size are suggested to clarify the possible interaction between rs9939609 variant or other variants of FTO gene and ALE supplementation in hypertriglyceridemia.
       
  • Investigating the effect of listening to the Holy Quran on the
           physiological responses of neonates admitted to neonatal intensive care
           units: a pilot study
    • Abstract: Publication date: Available online 29 August 2018Source: Advances in Integrative MedicineAuthor(s): Arina Qolizadeh, Zahra Tayebi Myaneh, Farnoosh Rashvand AimThe purpose of this study is to investigate the effect of listening to the Holy Quran on the physiological responses of neonates admitted to neonatal intensive care units.MethodsThe present clinical trial was conducted in Iran. The study sample consisted of 64 preterm neonates admitted to the neonatal intensive care units (32 of whom were in the Quranic voice group that listened to voice of Quran and 32 in the control group). Neonates’ physiological responses including heart rate, respiratory rate, arterial oxygen saturation percentage, mean arterial pressure and temperature were recorded every 10 minutes in three stages: immediately before the intervention, during the intervention (minutes 10 and 20 from the onset of intervention) and 10 minutes after the intervention.ResultsAccording to the findings during the intervention and 10 minutes after the intervention, the mean heart rate of the neonates in the intervention group was significantly lower. The results of this study demonstrated that the mean respiratory rate of neonates was significantly less in the intervention group during the intervention (P 
       
  • Association between increased intestinal permeability and disease: A
           systematic review
    • Abstract: Publication date: Available online 26 August 2018Source: Advances in Integrative MedicineAuthor(s): Bradley Leech, Janet Schloss, Amie Steel ObjectiveIncreased intestinal permeability (IP) may play an important role in health and disease. The purpose of this review is to explore the association between IP and diseases frequently found within clinical practice.Design and methodsA systematic literature search was conducted up until July 2018 in PubMed, EMBASE and AMED. A total of 48 articles met the inclusion/exclusion criteria.ResultsIP is strongly associated with autoimmune disease and liver conditions, with the estimated prevalence of 25-87.5% and 17-65% respectively. IP also correlates with diabetes (30-65%), food allergies/hypersensitivity, irritable bowel syndrome (35.6%), polycystic ovary syndrome and autism (36.7%). Disease severity in addition to clinical symptoms of menstrual disorders, food allergy or hypersensitivity directly correlates with IP. Finally, the severity of IP appears to be exacerbated by the presence of dysbiosis, inflammation and glucose metabolism disorders.ConclusionsIP is a potentially influential factor that coincides with a variety of health conditions and diseases. IP should be considered as a factor in the pathophysiology and differential diagnosis for patient’s presenting with autoimmune diseases, non-alcoholic fatty liver disease, liver cirrhosis, polycystic ovary syndrome, irritable bowel syndrome, diabetes, autism, food allergies and food hypersensitivity. Further research is required to determine if IP plays a pathogenic role in the progression and development of disease or whether the disease causes IP. While the clinical significance between IP and these diseases is unclear, the findings of the review suggest the treatment of IP in patients presenting with these conditions may warrant the consideration of clinicians.
       
  • How can mindfulness-led breathing of qigong/Tai Chi work on qi and the
           meridian network'
    • Abstract: Publication date: Available online 30 July 2018Source: Advances in Integrative MedicineAuthor(s): Chungda Lee It is known that Chinese qigong, including medical, meditative and martial arts qigong, comprises 3 modalities: mindfulness training, breathing manipulation and body posture. Qi of qi-gong is the vital energy of the body, and gong is the training skill of generating stimuli to work on and with qi. However, little attention has been paid on the mediators and biological mechanisms of qigong. The purpose of this article is to propose a theoretical framework to support the hypothesis that the integrative skill of mindfulness-led breathing (MLB) with accordant body posture (a critical component) generates mechanical stimuli (mediators) to produce changes on meridian network (mechanisms). Of note, recent studies have proposed that the meridian qi is biologically and anatomically consistent with the extracellular fluid within interstitial spaces and is the major source of lymph. MLB recruits primary and accessory respiratory muscles and produces pressure gradients in the entire body. Experimental data suggest that pressure gradients generated by active respiratory muscle contraction is required to support an efficient lymphatic drainage. MLB-contracted respiratory muscles (yin) and accordant extending body postures (yang) coincide with the yin-yang theory creating tensional forces to distend the joints and stretch the meridian network. Emergent advances in mechanobiology of connective tissues underpin the substantial effects of mechanical stretch in regulating tissue homeostasis. Therefore, this article claims that mechanical stimuli generated by qigong bring about the balancing of qi-blood and regulation of meridian network in addition to emotional regulation, which are all pivotal to the integrity of mind-body health.
       
  • Naturopathic Medical Student Empathy and Burnout: A Preliminary Study
    • Abstract: Publication date: Available online 17 July 2018Source: Advances in Integrative MedicineAuthor(s): Matthew Hicks, Douglas Hanes BackgroundMany studies have demonstrated empathy decline in medical students over the course of training. Burnout negatively affects academic or professional performance and has been negatively correlated with empathy. Neither empathy nor burnout has been previously studied in naturopathic medical students.ObjectiveThe aims of this cross-sectional study were to (1) compare empathy at different levels of training, (2) describe the prevalence of burnout, and (3) identify correlations between empathy and burnout, in naturopathic medical students.MethodsThis cross-sectional study used the Interpersonal Reactivity Index and Maslach Burnout Inventory to measure empathy and burnout, respectively, in an online survey of current naturopathic medical students at one institution.Results1) There was no significant difference in empathy between any cohorts or between those in internship versus those not in internship. 2) Among burnout outcomes, 42% of participants met criteria for emotional exhaustion, 19% for depersonalization, and 64% for low sense of personal accomplishment. 3) Cognitive empathy was positively correlated with affective empathy and a higher sense of personal accomplishment and negatively correlated with emotional exhaustion and depersonalization.ConclusionsWhile a longitudinal study would provide more definitive evidence, this study suggests that empathy in naturopathic medical students is relatively stable over the course of training. It also demonstrates that burnout is prevalent in this population and has an inverse relationship with empathy. Interventions to prevent burnout and increase empathy are discussed.
       
  • Use of Rigid Tape in Conjunction with Kinesio® Tape to Treat Post-Stroke
           Shoulder Pain: A Case Report
    • Abstract: Publication date: Available online 5 July 2018Source: Advances in Integrative MedicineAuthor(s): Natalia Noce, Caitlin Brady, Kimberly Hreha
       
  • The Effects of a Holistic-Patient-Centered Approach on Breast Cancer
           Relative Dose Intensity
    • Abstract: Publication date: Available online 2 July 2018Source: Advances in Integrative MedicineAuthor(s): Rebecca Louison, Jennifer E. Lee, Victoria Roe, Chirantan Ghosh PurposeA critical component of breast cancer (BC) chemotherapy effectiveness is Relative Dose Intensity (RDI), as
       
  • Setting an agenda for strengthening the evidence-base for traditional and
           complementary medicines: Perspectives from an expert forum in Australia
    • Abstract: Publication date: Available online 8 June 2018Source: Advances in Integrative MedicineAuthor(s): Rachel Canaway, Matthew Leach, Jennifer Hunter ObjectivesTo explore the challenges regarding evidence and complementary medicine in Australia and identify potential future directions to develop leadership, action and debate.DesignFacilitated discussion among a roundtable of experts to identify and consider the relevant issues and potential actions.MethodsPurposive sampling of 17 expert stakeholders with a variety of experience in the traditional and complementary medicine (T&CM) arena. Thematic analysis of the half-day discussion transcript resulted in a framework for a broad agenda to support the development of appropriate evidence for T&CM.ResultsFive key areas (with sub-themes) were identified, forming the backbone of an agenda-setting framework: focus areas; strategies; actions and outputs; barriers; and drivers of change. ‘Focus areas’ encapsulated the main themes and informed all key areas, these were: consumer perspectives and needs; hierarchies of evidence; safety of products, practitioners and practices; modernisation of T&CM; regulation and policy; and evidence-based practice. Two recurring themes informed the framework at multiple levels: the complexity and varied understanding of what is ‘appropriate evidence’ for T&CM; and putting consumers at the centre – to ensure that their needs and safety are prioritised. Lack of resources for undertaking T&CM research necessitates the need to bring together information from multiple sources so that ‘totalities of evidence’ can be assessed to increase the T&CM evidence-base. Doing so requires reassessment of the relative value of traditional forms of evidence and challenges current linear evidence hierarchies that prioritise clinical trials as the ‘gold standard’.ConclusionsThis Australian agenda-setting framework for strengthening T&CM evidence requires an interdisciplinary leadership group (including consumer, clinician, academic and industry representatives) to build consensus, foster collaboration, and generate and disseminate information. Prioritising the perspectives and needs of consumers should be a primary focus in taking the ‘strengthening evidence for T&CM’ agenda forward.
       
  • Adding a narrative practitioner perspective section to case report
           publications
    • Abstract: Publication date: Available online 7 June 2018Source: Advances in Integrative MedicineAuthor(s): Bevin Clare, Marybeth Missenda, John Courie Clinical case reports are opportunities to disseminate information on unique diagnoses and treatments through the reporting of objective and scientific data supplemented by the patient’s perspective on the outcomes. The practitioner has traditionally removed their own narrative which includes perspectives and bias relating to the encounter. The absence of this practitioner narrative in published case reports reflects an incomplete picture of the therapeutic relationship and can directly impact the applicability to clinical practice. Although guidelines on publishing case reports are focused on providing complete and transparent information from which to inform research design and allow aggregation for data analysis, the physician’s narrative involves the awareness of bias, distractions and recognition of shared experiences which influence the therapeutic relationship. In this paper we propose a three-phase process culminating in the inclusion of a physician narrative in published case reports to better reflect the humanity present in patient care.
       
  • Breastfeeding Difficulties: The Role of Integrative Medicine [IM] in
           Breastfeeding Support
    • Abstract: Publication date: Available online 5 April 2018Source: Advances in Integrative MedicineAuthor(s): Morns Melissa, Bowman Diana, Steel Amie
       
  • The potential downstream effects of proposed changes in Australian private
           health insurance policy: The case for naturopathy
    • Abstract: Publication date: Available online 4 April 2018Source: Advances in Integrative MedicineAuthor(s): Matthew J. Leach, Amie Steel The Australian government has recently announced major reforms to the private health insurance (PHI) system. Amongst the changes are the removal of government-subsidised PHI rebates for consultations with most unregistered complementary medicine practitioners, including naturopathy. However, there are several doubts about these reforms, as this commentary explains, which primarily relate to (1) the basis of the decision, and (2) the consequences of the proposed changes. In terms of the former, an insufficient clinical evidence base was claimed to be the main driver of this decision. However, the evidence informing this decision had several limitations, and in the case of naturopathy, was somewhat contradictory. The absence of enforceable standards (from statutory registration) was another factor contributing to the decision; yet, for naturopathy, this has largely been the product of government inaction, rather than a lack of action from the profession. In terms of the downstream effects of these reforms, these could be considerable, including mass membership withdrawal from ancillary (extras) cover and cost-shifting to the public health sector; potentially leading to a rise in PHI premiums, increased demand for general practice services, and a rise in the number of avoidable hospitalisations. The proposed changes also deviate from international standards and declarations, and contravene key performance indicators of a quality health care system. In light of these concerns, the commentary calls for an immediate rethink of the intended PHI reforms, at least for naturopathy.
       
  • Induction of remission in moderate-to-severe steroid refractory ulcerative
           colitis using patient-driven non-pharmacologic therapy
    • Abstract: Publication date: Available online 28 March 2018Source: Advances in Integrative MedicineAuthor(s): Alice M. Lee, Rohan Mandaliya, Mark C. Mattar
       
  • Medical synopsis: New metabolic markers to help diagnosis and assess
           disease progression for Alzheimer's disease, Normal Pressure Hydrocephalus
           and Brain Tumours
    • Abstract: Publication date: Available online 20 March 2018Source: Advances in Integrative MedicineAuthor(s): Janet Schloss
       
  • Aegle Marmelos Leaf Juice As A Complementary Therapy To Control Type 2
           Diabetes - Randomised Controlled Trial In Gujarat, India
    • Abstract: Publication date: Available online 13 March 2018Source: Advances in Integrative MedicineAuthor(s): Vinita Nigam, Vanisha S. Nambiar ObjectiveTo compare the clinical efficacy of Aegle Marmelos (L.) Correa (AMLC) leaf juice (supplementation (20 g/100 ml) for 60 days among type 2 diabetes mellitus subjects.DesignRandomized-controlled trial.SettingVeraval. Gir-Somnath, Gujarat, India.InterventionConfirmed Type 2 diabetes mellitus subjects (n = 60), were randomly divided to experimental (n = 30) AMLC leaf juice supplementation (20 g/100 ml) and Control group (n = 30) for 8 weeks. Main outcome measures: body-mass-index (BMI), body-fat-percent (BF%), Systolic and Diastolic blood pressure (BP), Fasting blood Glucose, glycosylated hemoglobin and Post prandial bolld glucose (FBG, HbA1c and PPBG), Total, High, Low and Very low density Lipoproteins and Triglycerides (TC, HDL, LDL-cholesterol and TG), C-reactive protein (CRP), liver enzyme tests serum glutamate oxaloacetate transaminase and, serum glutamate pyruvate transaminase (SGPT and SGOT), kidney function tests (Creatinine), total protein (TP, Albumin, globulin) and Serum Ferric Reducing Antioxidant Potential (serum FRAP).ResultsAt 4 weeks, significant reduction was recorded in blood pressure SBP- 6.45%; DBP- 4.6%, FBG & HbA1c-20%; PPBG-15%; Total Cholesterol (TC-8%), LDL-15%), Triglycerides (TG-11%), liver functions SGOT-19% and, SGPT-13%, increase in serum FRAP-18%) in the subjects of EG post supplementation compared to baseline. When compared to control group, it reduced BF%, FBG, HbA1c, cholesterol, TG, LDL-cholesterol, CRP and raised HDL-cholesterol as well as improved antioxidant activity.ConclusionAMLC leaf juice supplementation (20 g/100 ml) for 60 days showed improvement in all bio-chemical parameters of type 2 diabetes mellitus, with enhanced efficacy and negligible adverse-effects. This juice can therefore, be supplemented along with oral hypoglycemic drugs to keep the above parameters in control. AMLC leaf being easily available and low cost, can be used as complementary therapy in the management of diabetes possibly due to presence of active components, aegelin 2, scopoletin and sitosterol in the leaf.Trial Registration No: The study was approved by Ethics Committee of Department
       
  • A case report of a novel, integrative approach to Hashimoto’s
           thyroiditis with unexpected results
    • Abstract: Publication date: Available online 13 March 2018Source: Advances in Integrative MedicineAuthor(s): Nicole Avard, Suzanne J. Grant BackgroundHashimoto’s thyroiditis (HT) is an autoimmune illness of the thyroid gland. The presence of thyroid antibodies (Thyroglobulin Antibodies and Peroxidase Antibodies) is suggestive of the diagnosis. Patients can have Hashimoto’s thyroiditis without the presence of thyroid antibodies. The treatment of Hashimoto’s thyroiditis is usually expectant observation of the thyroid function and subsequent exogenous thyroid hormone replacement, if deemed appropriate. This case report outlines a novel approach that led to an improvement in symptoms, and a reduction in one thyroid antibody, for a young woman.CaseA 23 year old woman diagnosed with Hashimoto’s thyroiditis, 8 months prior, presented at her initial visit with symptoms of extreme fatigue, anxiety and hair loss. Her thyroid antibodies were strongly positive, with a normal TSH. She was commenced on a three-tiered integrative treatment plan, implemented by the clinic naturopath and general practitioner, working in a collaborative care model. This involved a gluten and grain free diet, support of her methylation cycle and anti-oxidant capacity with micronutrients, and stress management.ConclusionOver a treatment period of 15 months, using an integrative approach, she experienced clinical improvement in her symptoms and return to functional daily life, as well as a significant reduction in thyroid antibodies.
       
  • Medical synopsis: Should we be going nuts for good health'
    • Abstract: Publication date: Available online 21 February 2018Source: Advances in Integrative MedicineAuthor(s): Bradley J. McEwen
       
  • Medical Synopsis: Sugar and cardiometabolic disease - should we be
           quitting sugar'
    • Abstract: Publication date: Available online 21 February 2018Source: Advances in Integrative MedicineAuthor(s): Bradley J. McEwen
       
  • Medical Synopsis: The cardiometabolic benefits of chocolate - can
           chocolate be the elusive elixir to optimum health'
    • Abstract: Publication date: Available online 13 February 2018Source: Advances in Integrative MedicineAuthor(s): Bradley J. McEwen
       
  • Pharmacist's Knowledge and Attitudes towards Complementary and Alternative
           Medicine in Saudi Arabia: A Cross-Sectional Study
    • Abstract: Publication date: Available online 6 February 2018Source: Advances in Integrative MedicineAuthor(s): Lamya Alnaim, Saja Almazrou, Maha Alsunbul, Alaa Alhaji, Amani Alenazi, Sahar Alboami ObjectiveComplementary and Alternative Medicine (CAM) is defined as a domain of diverse medical and healthcare systems, practices, and products that are not considered as a significant part of conventional medicine. The study has aimed to assess hospital and clinical pharmacist perceptions, experience, and knowledge toward CAM; and determined commonly used information resources to answer CAM-related inquiries.DesignThe study has incorporated cross-sectional analysis using a questionnaire developed by item generation through a review of scientific literature and focus groups.MethodsMost survey questions were adapted from ‘Rural Australian community pharmacists’ views on complementary and alternative medicine. A total of 199 pharmacists completed the survey.Results20% of the participants indicated that they have completed their post-graduation in CAM qualification. It has been evaluated that 53% of the participants did not believe in the safety of CAM, and about 60% of participants were confident in discussing CAM therapy with the patients. Internet was the common route, used by participants to search for information regarding CAM. The relationship between different demographic variables and the attitude score of the participants was statistically significant (P = 0.015). This is because pharmacists, who received postgraduate CAM qualification, had higher attitude score as compared to those, who did not receive post-graduate CAM qualification. There were also statistically significant differences (P = 0.008) amongst the pharmacists, who frequently, sometimes, occasionally, or never recommend complementary medicine to the patients.ConclusionPharmacists play an important role in ensuring that CAMs are used safely and appropriately; therefore, they need to be better informed about CAMs and better able to advise patients, seeking alternative remedies.
       
  • Red yeast rice as an adjunct to sertraline for treatment of depression in
           patients with percutaneous coronary intervention: Placebo-controlled trial
           
    • Abstract: Publication date: Available online 6 February 2018Source: Advances in Integrative MedicineAuthor(s): Parisa Divsalar, Ahmad Ali Noorbala, E. Moazen-Zadeh, Morteza Jafarinia, Mansour Shakiba, Nazila Shahmansouri, Maryam Ghazizadeh-Hashemi, Farnaz Etesam, Shahin Akhondzadeh ObjectivesRed yeast rice (RYR) has demonstrated neuroprotective effects in animal studies. The aim of this study was to access the efficacy of RYR for treatment of depression in patients with recent history of percutaneous coronary intervention.DesignThis was a 6-week double-blind placebo-controlled randomized clinical trial.SettingParticipants included outpatient men and women aged 18 to 60 years old with history of coronary angioplasty, diagnosis of major depressive disorder based on the Diagnostic and Statistical Manual of Mental Disorders (DSM-V), and Hamilton Depression Rating Scale (HDRS) score of ≥20. Candidates were excluded in case of any other DSM-V disorders, use of lipid lowering agents in the last two weeks, elevated serum aminotransferases or serum LDL ≤ 80 mg/dL.InterventionsPatients received sertraline (200 mg/day) plus either red yeast rice commercially available capsules (2400 mg/day) containing 10.05 mg/day lovastatin or placebo.Main outcome measuresThe primary outcome was the difference in mean change of the HDRS score from baseline to endpoint between the two treatment arms.ResultsThe primary outcome approached significance (Mean difference in score change(CI95%) = −1.24 (−2.51 to 0.03), p = .056) and was accompanied by a significant time × treatment interaction effect [Two-way ANOVA: F (df, mean square) = 4.42 (2, 13.687), p = .015]. There was no significant difference between the two treatment arms in terms of lipid profile, liver function tests, or incidence of adverse events.ConclusionsThis is the first report on the benefits of RYR in treatment of depression. Future studies are warranted to confirm our findings and scrutinize the mechanisms of action.
       
  • Effects of turmeric and chicory seed supplementation on antioxidant and
           inflammatory biomarkers in patients with non-alcoholic fatty liver disease
           (NAFLD)
    • Abstract: Publication date: Available online 6 February 2018Source: Advances in Integrative MedicineAuthor(s): Aida Ghaffari, Maryam Rafraf, Roya Navekar, Mohammad Asghari-Jafarabadi BackgroundTo evaluate effects of turmeric (Curcuma longa L) and chicory seed (Cichorium intybus L) consumption on antioxidant status and inflammatory biomarkers in patients with non-alcoholic fatty liver disease (NAFLD).MethodsIn this double-blind, randomized controlled clinical trial, 92 patients with NAFLD (46 males and 46 females) aged 20–60 year with body mass index (BMI) ranged 24.9-40 kg/m2 were randomly assigned to 4 groups as follows: group TUR (n = 23) consumed 3 g/d turmeric; group CHI (n = 23) infused 9 g/d of powdered chicory seed; group TUR+CHI (n = 23) turmeric and chicory seed administered together (3 g/d turmeric + infused 9 g/d chicory seed); group PLA (n = 23) received placebo (6 × 500 mg corn starch capsules). Fasting blood samples, anthropometric measurements, physical activity and dietary records were collected at baseline and at the end of 12 weeks. All analyses were conducted on an intention-to-treat basis.ResultsSignificant decreases were observed in BMI of subjects in CHI and TUR + CHI groups, compared with PLA group (P 
       
 
 
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