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Publisher: Elsevier   (Total: 3042 journals)

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Showing 1 - 200 of 3042 Journals sorted alphabetically
AASRI Procedia     Open Access   (Followers: 15)
Academic Pediatrics     Hybrid Journal   (Followers: 19, SJR: 1.402, h-index: 51)
Academic Radiology     Hybrid Journal   (Followers: 16, SJR: 1.008, h-index: 75)
Accident Analysis & Prevention     Partially Free   (Followers: 81, SJR: 1.109, h-index: 94)
Accounting Forum     Hybrid Journal   (Followers: 23, SJR: 0.612, h-index: 27)
Accounting, Organizations and Society     Hybrid Journal   (Followers: 27, SJR: 2.515, h-index: 90)
Achievements in the Life Sciences     Open Access   (Followers: 4)
Acta Anaesthesiologica Taiwanica     Open Access   (Followers: 5, SJR: 0.338, h-index: 19)
Acta Astronautica     Hybrid Journal   (Followers: 328, SJR: 0.726, h-index: 43)
Acta Automatica Sinica     Full-text available via subscription   (Followers: 3)
Acta Biomaterialia     Hybrid Journal   (Followers: 25, SJR: 2.02, h-index: 104)
Acta Colombiana de Cuidado Intensivo     Full-text available via subscription  
Acta de Investigación Psicológica     Open Access   (Followers: 2)
Acta Ecologica Sinica     Open Access   (Followers: 8, SJR: 0.172, h-index: 29)
Acta Haematologica Polonica     Free   (SJR: 0.123, h-index: 8)
Acta Histochemica     Hybrid Journal   (Followers: 3, SJR: 0.604, h-index: 38)
Acta Materialia     Hybrid Journal   (Followers: 205, SJR: 3.683, h-index: 202)
Acta Mathematica Scientia     Full-text available via subscription   (Followers: 5, SJR: 0.615, h-index: 21)
Acta Mechanica Solida Sinica     Full-text available via subscription   (Followers: 9, SJR: 0.442, h-index: 21)
Acta Oecologica     Hybrid Journal   (Followers: 9, SJR: 0.915, h-index: 53)
Acta Otorrinolaringologica (English Edition)     Full-text available via subscription   (Followers: 1)
Acta Otorrinolaringológica Española     Full-text available via subscription   (Followers: 3, SJR: 0.311, h-index: 16)
Acta Pharmaceutica Sinica B     Open Access   (Followers: 2)
Acta Poética     Open Access   (Followers: 4)
Acta Psychologica     Hybrid Journal   (Followers: 22, SJR: 1.365, h-index: 73)
Acta Sociológica     Open Access  
Acta Tropica     Hybrid Journal   (Followers: 5, SJR: 1.059, h-index: 77)
Acta Urológica Portuguesa     Open Access  
Actas Dermo-Sifiliograficas     Full-text available via subscription   (Followers: 4)
Actas Dermo-Sifiliográficas (English Edition)     Full-text available via subscription   (Followers: 3)
Actas Urológicas Españolas     Full-text available via subscription   (Followers: 4, SJR: 0.383, h-index: 19)
Actas Urológicas Españolas (English Edition)     Full-text available via subscription   (Followers: 2)
Actualites Pharmaceutiques     Full-text available via subscription   (Followers: 5, SJR: 0.141, h-index: 3)
Actualites Pharmaceutiques Hospitalieres     Full-text available via subscription   (Followers: 4, SJR: 0.112, h-index: 2)
Acupuncture and Related Therapies     Hybrid Journal   (Followers: 3)
Ad Hoc Networks     Hybrid Journal   (Followers: 11, SJR: 0.967, h-index: 57)
Addictive Behaviors     Hybrid Journal   (Followers: 15, SJR: 1.514, h-index: 92)
Addictive Behaviors Reports     Open Access   (Followers: 5)
Additive Manufacturing     Hybrid Journal   (Followers: 7, SJR: 1.039, h-index: 5)
Additives for Polymers     Full-text available via subscription   (Followers: 20)
Advanced Drug Delivery Reviews     Hybrid Journal   (Followers: 124, SJR: 5.2, h-index: 222)
Advanced Engineering Informatics     Hybrid Journal   (Followers: 11, SJR: 1.265, h-index: 53)
Advanced Powder Technology     Hybrid Journal   (Followers: 16, SJR: 0.739, h-index: 33)
Advances in Accounting     Hybrid Journal   (Followers: 9, SJR: 0.299, h-index: 15)
Advances in Agronomy     Full-text available via subscription   (Followers: 15, SJR: 2.071, h-index: 82)
Advances in Anesthesia     Full-text available via subscription   (Followers: 25, SJR: 0.169, h-index: 4)
Advances in Antiviral Drug Design     Full-text available via subscription   (Followers: 3)
Advances in Applied Mathematics     Full-text available via subscription   (Followers: 6, SJR: 1.054, h-index: 35)
Advances in Applied Mechanics     Full-text available via subscription   (Followers: 10, SJR: 0.801, h-index: 26)
Advances in Applied Microbiology     Full-text available via subscription   (Followers: 21, SJR: 1.286, h-index: 49)
Advances In Atomic, Molecular, and Optical Physics     Full-text available via subscription   (Followers: 16, SJR: 3.31, h-index: 42)
Advances in Biological Regulation     Hybrid Journal   (Followers: 4, SJR: 2.277, h-index: 43)
Advances in Botanical Research     Full-text available via subscription   (Followers: 3, SJR: 0.619, h-index: 48)
Advances in Cancer Research     Full-text available via subscription   (Followers: 25, SJR: 2.215, h-index: 78)
Advances in Carbohydrate Chemistry and Biochemistry     Full-text available via subscription   (Followers: 9, SJR: 0.9, h-index: 30)
Advances in Catalysis     Full-text available via subscription   (Followers: 5, SJR: 2.139, h-index: 42)
Advances in Cellular and Molecular Biology of Membranes and Organelles     Full-text available via subscription   (Followers: 12)
Advances in Chemical Engineering     Full-text available via subscription   (Followers: 24, SJR: 0.183, h-index: 23)
Advances in Child Development and Behavior     Full-text available via subscription   (Followers: 10, SJR: 0.665, h-index: 29)
Advances in Chronic Kidney Disease     Full-text available via subscription   (Followers: 8, SJR: 1.268, h-index: 45)
Advances in Clinical Chemistry     Full-text available via subscription   (Followers: 28, SJR: 0.938, h-index: 33)
Advances in Colloid and Interface Science     Full-text available via subscription   (Followers: 18, SJR: 2.314, h-index: 130)
Advances in Computers     Full-text available via subscription   (Followers: 16, SJR: 0.223, h-index: 22)
Advances in Developmental Biology     Full-text available via subscription   (Followers: 11)
Advances in Digestive Medicine     Open Access   (Followers: 4)
Advances in DNA Sequence-Specific Agents     Full-text available via subscription   (Followers: 5)
Advances in Drug Research     Full-text available via subscription   (Followers: 22)
Advances in Ecological Research     Full-text available via subscription   (Followers: 39, SJR: 3.25, h-index: 43)
Advances in Engineering Software     Hybrid Journal   (Followers: 25, SJR: 0.486, h-index: 10)
Advances in Experimental Biology     Full-text available via subscription   (Followers: 7)
Advances in Experimental Social Psychology     Full-text available via subscription   (Followers: 40, SJR: 5.465, h-index: 64)
Advances in Exploration Geophysics     Full-text available via subscription   (Followers: 3)
Advances in Fluorine Science     Full-text available via subscription   (Followers: 8)
Advances in Food and Nutrition Research     Full-text available via subscription   (Followers: 45, SJR: 0.674, h-index: 38)
Advances in Fuel Cells     Full-text available via subscription   (Followers: 14)
Advances in Genetics     Full-text available via subscription   (Followers: 15, SJR: 2.558, h-index: 54)
Advances in Genome Biology     Full-text available via subscription   (Followers: 12)
Advances in Geophysics     Full-text available via subscription   (Followers: 6, SJR: 2.325, h-index: 20)
Advances in Heat Transfer     Full-text available via subscription   (Followers: 20, SJR: 0.906, h-index: 24)
Advances in Heterocyclic Chemistry     Full-text available via subscription   (Followers: 8, SJR: 0.497, h-index: 31)
Advances in Human Factors/Ergonomics     Full-text available via subscription   (Followers: 24)
Advances in Imaging and Electron Physics     Full-text available via subscription   (Followers: 2, SJR: 0.396, h-index: 27)
Advances in Immunology     Full-text available via subscription   (Followers: 34, SJR: 4.152, h-index: 85)
Advances in Inorganic Chemistry     Full-text available via subscription   (Followers: 9, SJR: 1.132, h-index: 42)
Advances in Insect Physiology     Full-text available via subscription   (Followers: 3, SJR: 1.274, h-index: 27)
Advances in Integrative Medicine     Hybrid Journal   (Followers: 4)
Advances in Intl. Accounting     Full-text available via subscription   (Followers: 4)
Advances in Life Course Research     Hybrid Journal   (Followers: 8, SJR: 0.764, h-index: 15)
Advances in Lipobiology     Full-text available via subscription   (Followers: 2)
Advances in Magnetic and Optical Resonance     Full-text available via subscription   (Followers: 9)
Advances in Marine Biology     Full-text available via subscription   (Followers: 16, SJR: 1.645, h-index: 45)
Advances in Mathematics     Full-text available via subscription   (Followers: 10, SJR: 3.261, h-index: 65)
Advances in Medical Sciences     Hybrid Journal   (Followers: 5, SJR: 0.489, h-index: 25)
Advances in Medicinal Chemistry     Full-text available via subscription   (Followers: 5)
Advances in Microbial Physiology     Full-text available via subscription   (Followers: 4, SJR: 1.44, h-index: 51)
Advances in Molecular and Cell Biology     Full-text available via subscription   (Followers: 22)
Advances in Molecular and Cellular Endocrinology     Full-text available via subscription   (Followers: 10)
Advances in Molecular Toxicology     Full-text available via subscription   (Followers: 7, SJR: 0.324, h-index: 8)
Advances in Nanoporous Materials     Full-text available via subscription   (Followers: 4)
Advances in Oncobiology     Full-text available via subscription   (Followers: 3)
Advances in Organometallic Chemistry     Full-text available via subscription   (Followers: 15, SJR: 2.885, h-index: 45)
Advances in Parallel Computing     Full-text available via subscription   (Followers: 7, SJR: 0.148, h-index: 11)
Advances in Parasitology     Full-text available via subscription   (Followers: 7, SJR: 2.37, h-index: 73)
Advances in Pediatrics     Full-text available via subscription   (Followers: 21, SJR: 0.4, h-index: 28)
Advances in Pharmaceutical Sciences     Full-text available via subscription   (Followers: 13)
Advances in Pharmacology     Full-text available via subscription   (Followers: 15, SJR: 1.718, h-index: 58)
Advances in Physical Organic Chemistry     Full-text available via subscription   (Followers: 7, SJR: 0.384, h-index: 26)
Advances in Phytomedicine     Full-text available via subscription  
Advances in Planar Lipid Bilayers and Liposomes     Full-text available via subscription   (Followers: 3, SJR: 0.248, h-index: 11)
Advances in Plant Biochemistry and Molecular Biology     Full-text available via subscription   (Followers: 8)
Advances in Plant Pathology     Full-text available via subscription   (Followers: 5)
Advances in Porous Media     Full-text available via subscription   (Followers: 4)
Advances in Protein Chemistry     Full-text available via subscription   (Followers: 18)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 19, SJR: 1.5, h-index: 62)
Advances in Psychology     Full-text available via subscription   (Followers: 58)
Advances in Quantum Chemistry     Full-text available via subscription   (Followers: 5, SJR: 0.478, h-index: 32)
Advances in Radiation Oncology     Open Access  
Advances in Small Animal Medicine and Surgery     Hybrid Journal   (Followers: 2, SJR: 0.1, h-index: 2)
Advances in Space Research     Full-text available via subscription   (Followers: 339, SJR: 0.606, h-index: 65)
Advances in Structural Biology     Full-text available via subscription   (Followers: 8)
Advances in Surgery     Full-text available via subscription   (Followers: 6, SJR: 0.823, h-index: 27)
Advances in the Study of Behavior     Full-text available via subscription   (Followers: 29, SJR: 1.321, h-index: 56)
Advances in Veterinary Medicine     Full-text available via subscription   (Followers: 15)
Advances in Veterinary Science and Comparative Medicine     Full-text available via subscription   (Followers: 13)
Advances in Virus Research     Full-text available via subscription   (Followers: 5, SJR: 1.878, h-index: 68)
Advances in Water Resources     Hybrid Journal   (Followers: 43, SJR: 2.408, h-index: 94)
Aeolian Research     Hybrid Journal   (Followers: 5, SJR: 0.973, h-index: 22)
Aerospace Science and Technology     Hybrid Journal   (Followers: 308, SJR: 0.816, h-index: 49)
AEU - Intl. J. of Electronics and Communications     Hybrid Journal   (Followers: 8, SJR: 0.318, h-index: 36)
African J. of Emergency Medicine     Open Access   (Followers: 5, SJR: 0.344, h-index: 6)
Ageing Research Reviews     Hybrid Journal   (Followers: 7, SJR: 3.289, h-index: 78)
Aggression and Violent Behavior     Hybrid Journal   (Followers: 422, SJR: 1.385, h-index: 72)
Agri Gene     Hybrid Journal  
Agricultural and Forest Meteorology     Hybrid Journal   (Followers: 15, SJR: 2.18, h-index: 116)
Agricultural Systems     Hybrid Journal   (Followers: 30, SJR: 1.275, h-index: 74)
Agricultural Water Management     Hybrid Journal   (Followers: 38, SJR: 1.546, h-index: 79)
Agriculture and Agricultural Science Procedia     Open Access  
Agriculture and Natural Resources     Open Access   (Followers: 1)
Agriculture, Ecosystems & Environment     Hybrid Journal   (Followers: 50, SJR: 1.879, h-index: 120)
Ain Shams Engineering J.     Open Access   (Followers: 5, SJR: 0.434, h-index: 14)
Air Medical J.     Hybrid Journal   (Followers: 5, SJR: 0.234, h-index: 18)
AKCE Intl. J. of Graphs and Combinatorics     Open Access   (SJR: 0.285, h-index: 3)
Alcohol     Hybrid Journal   (Followers: 10, SJR: 0.922, h-index: 66)
Alcoholism and Drug Addiction     Open Access   (Followers: 6)
Alergologia Polska : Polish J. of Allergology     Full-text available via subscription   (Followers: 1)
Alexandria Engineering J.     Open Access   (Followers: 1, SJR: 0.436, h-index: 12)
Alexandria J. of Medicine     Open Access  
Algal Research     Partially Free   (Followers: 8, SJR: 2.05, h-index: 20)
Alkaloids: Chemical and Biological Perspectives     Full-text available via subscription   (Followers: 3)
Allergologia et Immunopathologia     Full-text available via subscription   (Followers: 1, SJR: 0.46, h-index: 29)
Allergology Intl.     Open Access   (Followers: 5, SJR: 0.776, h-index: 35)
ALTER - European J. of Disability Research / Revue Européenne de Recherche sur le Handicap     Full-text available via subscription   (Followers: 6, SJR: 0.158, h-index: 9)
Alzheimer's & Dementia     Hybrid Journal   (Followers: 46, SJR: 4.289, h-index: 64)
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring     Open Access   (Followers: 5)
Alzheimer's & Dementia: Translational Research & Clinical Interventions     Open Access   (Followers: 3)
American Heart J.     Hybrid Journal   (Followers: 47, SJR: 3.157, h-index: 153)
American J. of Cardiology     Hybrid Journal   (Followers: 44, SJR: 2.063, h-index: 186)
American J. of Emergency Medicine     Hybrid Journal   (Followers: 34, SJR: 0.574, h-index: 65)
American J. of Geriatric Pharmacotherapy     Full-text available via subscription   (Followers: 6, SJR: 1.091, h-index: 45)
American J. of Geriatric Psychiatry     Hybrid Journal   (Followers: 15, SJR: 1.653, h-index: 93)
American J. of Human Genetics     Hybrid Journal   (Followers: 30, SJR: 8.769, h-index: 256)
American J. of Infection Control     Hybrid Journal   (Followers: 24, SJR: 1.259, h-index: 81)
American J. of Kidney Diseases     Hybrid Journal   (Followers: 32, SJR: 2.313, h-index: 172)
American J. of Medicine     Hybrid Journal   (Followers: 44, SJR: 2.023, h-index: 189)
American J. of Medicine Supplements     Full-text available via subscription   (Followers: 3)
American J. of Obstetrics and Gynecology     Hybrid Journal   (Followers: 179, SJR: 2.255, h-index: 171)
American J. of Ophthalmology     Hybrid Journal   (Followers: 54, SJR: 2.803, h-index: 148)
American J. of Ophthalmology Case Reports     Open Access   (Followers: 2)
American J. of Orthodontics and Dentofacial Orthopedics     Full-text available via subscription   (Followers: 6, SJR: 1.249, h-index: 88)
American J. of Otolaryngology     Hybrid Journal   (Followers: 23, SJR: 0.59, h-index: 45)
American J. of Pathology     Hybrid Journal   (Followers: 23, SJR: 2.653, h-index: 228)
American J. of Preventive Medicine     Hybrid Journal   (Followers: 21, SJR: 2.764, h-index: 154)
American J. of Surgery     Hybrid Journal   (Followers: 33, SJR: 1.286, h-index: 125)
American J. of the Medical Sciences     Hybrid Journal   (Followers: 12, SJR: 0.653, h-index: 70)
Ampersand : An Intl. J. of General and Applied Linguistics     Open Access   (Followers: 5)
Anaerobe     Hybrid Journal   (Followers: 4, SJR: 1.066, h-index: 51)
Anaesthesia & Intensive Care Medicine     Full-text available via subscription   (Followers: 53, SJR: 0.124, h-index: 9)
Anaesthesia Critical Care & Pain Medicine     Full-text available via subscription   (Followers: 5)
Anales de Cirugia Vascular     Full-text available via subscription  
Anales de Pediatría     Full-text available via subscription   (Followers: 2, SJR: 0.209, h-index: 27)
Anales de Pediatría (English Edition)     Full-text available via subscription  
Anales de Pediatría Continuada     Full-text available via subscription   (SJR: 0.104, h-index: 3)
Analytic Methods in Accident Research     Hybrid Journal   (Followers: 2, SJR: 2.577, h-index: 7)
Analytica Chimica Acta     Hybrid Journal   (Followers: 38, SJR: 1.548, h-index: 152)
Analytical Biochemistry     Hybrid Journal   (Followers: 160, SJR: 0.725, h-index: 154)
Analytical Chemistry Research     Open Access   (Followers: 8, SJR: 0.18, h-index: 2)
Analytical Spectroscopy Library     Full-text available via subscription   (Followers: 10)
Anesthésie & Réanimation     Full-text available via subscription  
Anesthesiology Clinics     Full-text available via subscription   (Followers: 21, SJR: 0.421, h-index: 40)
Angiología     Full-text available via subscription   (SJR: 0.124, h-index: 9)
Angiologia e Cirurgia Vascular     Open Access  
Animal Behaviour     Hybrid Journal   (Followers: 153, SJR: 1.907, h-index: 126)
Animal Feed Science and Technology     Hybrid Journal   (Followers: 5, SJR: 1.151, h-index: 83)
Animal Reproduction Science     Hybrid Journal   (Followers: 5, SJR: 0.711, h-index: 78)
Annales d'Endocrinologie     Full-text available via subscription   (SJR: 0.394, h-index: 30)
Annales d'Urologie     Full-text available via subscription  
Annales de Cardiologie et d'Angéiologie     Full-text available via subscription   (SJR: 0.177, h-index: 13)
Annales de Chirurgie de la Main et du Membre Supérieur     Full-text available via subscription  
Annales de Chirurgie Plastique Esthétique     Full-text available via subscription   (Followers: 2, SJR: 0.354, h-index: 22)
Annales de Chirurgie Vasculaire     Full-text available via subscription   (Followers: 1)

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Journal Cover Actas Dermo-Sifiliograficas
  [4 followers]  Follow
    
   Full-text available via subscription Subscription journal
   ISSN (Print) 0001-7310
   Published by Elsevier Homepage  [3042 journals]
  • Dermoscopy of Disseminated Superficial Actinic Porokeratosis
    • Authors: A. Nicola; J. Magliano
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): A. Nicola, J. Magliano
      We present a series of 6 cases of disseminated superficial actinic porokeratosis and describe their dermoscopic features. Dermoscopy is a noninvasive in vivo technique that is useful as a tool for the diagnosis and follow-up of porokeratosis. This condition has specific dermoscopic features that were observed in our series of cases and that are consistent with reports in the international literature.

      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2015.09.025
       
  • No aparecen más síntomas obsesivo-compulsivos en madres de hijos con
           dermatitis atópica
    • Authors: J. Olivera Pueyo
      First page: 392
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): J. Olivera Pueyo


      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2017.02.007
       
  • Fármacos anti-TNF, anticuerpos antinucleares y autoinmunidad en
           pacientes con psoriasis
    • Authors: P. de la Cueva Dobao
      Pages: 393 - 394
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): P. de la Cueva Dobao


      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2017.02.003
       
  • Enfermedad xantogranulomatosa orbitaria del adulto. Formas clínicas,
           evaluación y manejo
    • Authors: J.M. Ortiz Salvador; D. Subiabre Ferrer; A. Pérez Ferriols
      Pages: 400 - 406
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): J.M. Ortiz Salvador, D. Subiabre Ferrer, A. Pérez Ferriols
      La enfermedad xantogranulomatosa orbitaria del adulto comprende un grupo heterogéneo de síndromes clínicos con diferentes grados de afectación sistémica y pronóstico variable. Todas las formas se manifiestan clínicamente como lesiones amarillentas infiltradas orbitarias de crecimiento progresivo. Histológicamente se caracteriza por un infiltrado inflamatorio compuesto fundamentalmente por histiocitos espumosos y células gigantes multinucleadas tipo Touton. Estos histiocitos xantomatizados son CD68+, S100– y CD1a–. Existen 4 formas clínicas de enfermedad xantogranulomatosa orbitaria del adulto: el xantogranuloma orbitario del adulto, el asma del adulto asociado a xantogranulomas orbitarios, el xantogranuloma necrobiótico y la enfermedad de Erdheim-Chester. El tratamiento de las lesiones locales se basa fundamentalmente en corticosteroides sistémicos y otros inmunosupresores. En los casos con enfermedad sistémica vemurafenib, tocilizumab y sirolimus ofrecen resultados prometedores. Adult xanthogranulomatous disease of the orbit refers to a heterogeneous group of clinical syndromes with differing degrees of systemic involvement and distinct prognoses. The different syndromes all present clinically with progressively enlarging, yellowish lesions of the orbit. Histologically, the lesions are characterized by an inflammatory infiltrate of foam cells and Touton-type multinucleated giant cells. The xanthomatized histiocytes are CD68+, S100−, and CD1a−. There are 4 clinical forms of xanthogranulomatous disease of the orbit: adult xanthogranulomatous disease of the orbit, adult onset asthma and periocular xanthogranuloma, necrobiotic xanthogranuloma, and Erdheim-Chester disease. The treatment of local lesions are treated with systemic corticosteroids and other immunosuppressors. Vemurafenib, tocilizumab, and sirolimus have shown promising results in systemic disease.
      Graphical abstract image

      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2016.12.005
       
  • Síndrome de Sturge-Weber: revisión
    • Authors: E. Higueros; E. Roe; E. Granell; E. Baselga
      Pages: 407 - 417
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): E. Higueros, E. Roe, E. Granell, E. Baselga
      El síndrome de Sturge Weber es un trastorno neurocutáneo congénito, esporádico causado por una mutación somática activadora en el gen GNAQ, con una incidencia de uno de cada 20,000-50,000 nacidos. Se caracteriza por la presencia de una mancha en vino de Oporto facial, angiomatosis leptomeníngea y glaucoma. La manifestación neurológica más común son las convulsiones, que suelen comenzar en los primeros meses de vida. El glaucoma puede estar presente desde el nacimiento o desarrollarse posteriormente. Los estudios de neuroimagen permiten visualizar la angiomatosis leptomeníngea, ayudando al diagnóstico del síndrome de Sturge Weber. El tratamiento estándar incluye láser para la mancha en vino de Oporto facial, anticonvulsivantes y tratamiento médico o quirúrgico del glaucoma. El pronóstico de la enfermedad dependerá de la extensión de la malformación leptomeníngea y del grado de afectación ocular. Sturge-Weber syndrome is a sporadic congenital neurocutaneous disorder caused by a somatic activating mutation in GNAQ; it affects 1 in every 20,000 to 50,000 newborns. It is characterized by a facial Port-wine stain, leptomeningeal angiomatosis, and glaucoma. Seizures are the most common neurological manifestation and typically present in the first months of life. Glaucoma may be present at birth or develop later. Neuroimaging studies show leptomeningeal angiomatosis, supporting diagnosis. Standard treatment for Sturge-Weber syndrome includes laser treatment for the Port-wine stain, anticonvulsants, and medical or surgical treatment for the glaucoma. Prognosis depends on the extent of leptomeningeal involvement and the severity of the glaucoma.
      Graphical abstract image

      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2016.09.022
       
  • Omalizumab en el tratamiento de la urticaria crónica inducible
    • Authors: P. Chicharro; P. Rodríguez; D. de Argila
      Pages: 423 - 431
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): P. Chicharro, P. Rodríguez, D. de Argila
      Omalizumab es un anticuerpo monoclonal recombinante humanizado anti-IgE actualmente aprobado para el tratamiento del asma grave y de la urticaria crónica espontánea refractarios a otros tratamientos. Su empleo en el manejo de las urticarias crónicas inducibles (aquellas que se desencadenan ante determinados estímulos), si bien está contemplado en algunas guías de consenso, sigue siendo un uso «fuera de indicación». El objetivo de esta revisión es reunir los casos y series de casos publicados de este tipo de urticarias tratadas con omalizumab, analizando las características más relevantes y los resultados terapéuticos. Los resultados parecen posicionar a omalizumab como una potencial alternativa eficaz y segura en el tratamiento de algunos casos de urticaria crónica inducible. Omalizumab is a recombinant humanized monoclonal antibody that inhibits immunoglobulin E. It has been approved for the treatment of severe asthma and chronic spontaneous urticaria refractory to other treatments. Its use in the management of chronic inducible urticaria (a type triggered by certain stimuli) is still considered off-label, although this use has been discussed in some consensus papers. This review brings together case reports and case series describing the use of omalizumab to treat chronic inducible urticaria. We analyze the most important aspects of the cases and the outcomes reported. The results seem to position omalizumab as a potentially effective, safe treatment alternative in some cases of chronic inducible urticaria.
      Graphical abstract image

      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2016.07.018
       
  • Exéresis en U para la onicocriptosis
    • Authors: J. Correa; J. Magliano; C. Agorio; C. Bazzano
      Pages: 438 - 444
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): J. Correa, J. Magliano, C. Agorio, C. Bazzano
      Introducción y objetivos La onicocriptosis (OC), problema común, afecta principalmente a adultos jóvenes, siendo a menudo el hallux el más afectado. Dependiendo de la gravedad y cronicidad existen 4 estadios, y de estos se derivan distintos tratamientos, abarcando tanto técnicas conservadoras como quirúrgicas. Presentamos nuestra experiencia en esta afección, destacando las características de nuestra población, y dentro de los tratamientos quirúrgicos la técnica de exéresis en U. Materiales y métodos Estudio retrospectivo y descriptivo de pacientes que presentaron OC a nivel del hallux, que fueron resueltos quirúrgicamente a través de la exéresis en U y su manejo postoperatorio. Resultados De 10 pacientes operados la edad media fue 35,7 años, en donde 9 tenían compromiso de un hallux y uno de ambos. El estadio ii fue el predominante. La mitad había recibido tratamiento quirúrgico previo con una técnica distinta a la exéresis en U. El tiempo de cicatrización promedio fue 6 de semanas. Respecto a las complicaciones, solo un paciente sufrió una infección postoperatoria; y respecto del dolor posquirúrgico este fue leve-moderado, con duración de una semana. La mayoría estaba satisfecha con el resultado estético. Conclusiones Consideramos que la exéresis en U es una técnica que ha demostrado ser de gran utilidad cuando la OC se encuentra en estadio ii, y/o cuando el paciente ya ha recibido tratamiento quirúrgico que ha fallado. Además, sería de elección en los estadios iii y iv, donde lo que predomina es un exceso de tejido hipertrófico. Introduction and objectives Ingrown nails are a common problem, seen mostly in young adults. Also known as onychcrypotisis, this condition typically affects the great toenail. Four stages have been defined according to the severity and duration of the condition, and treatment varies from conservative to surgical techniques depending on the stage. We present our experience with this condition, describing the characteristics of our population and surgical treatment, in particular the super U technique. Material and methods This was a retrospective, descriptive study of patients with ingrown great toenail treated surgically using the super U technique. We also describe postoperative management. Results Ten patients with a mean age of 35.7 years underwent operation, 9 for unilateral ingrown great toenail and 1 for bilateral disease. Stage II ingrown nail was the most common. Half of the patients had been treated previously using other surgical techniques. The mean time to healing was 6 weeks. The only postoperative complication was infection in 1 patient. Mild to moderate postoperative pain persisted for a week. The majority of patients were satisfied with the cosmetic result. Conclusions We believe the super U technique is very useful in stage II ingrown nail and in disease that has recurred after previous surgery, and is the treatment of choice in stage III or IV disease in which excessive hypertrophic tissue is found.
      Graphical abstract
      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2017.01.010
       
  • Inducción de anticuerpos y enfermedades autoinmunes en pacientes con
           psoriasis tratados con fármacos anti-TNFα
    • Authors: B. Oter-López; M. Llamas-Velasco; J. Sánchez-Pérez; E. Dauden
      Pages: 445 - 456
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): B. Oter-López, M. Llamas-Velasco, J. Sánchez-Pérez, E. Dauden
      Introducción Se ha descrito la inducción de anticuerpos antinucleares (ANA) y el desarrollo de enfermedades autoinmunes tras el tratamiento con fármacos anti-TNFα, aunque existe controversia sobre su significado. Objetivos Determinar la aparición de enfermedades autoinmunes y de autoanticuerpos en pacientes psoriásicos tratados con fármacos anti-TNFα subcutáneos (adalimumab y etanercept). Relacionar su desarrollo con la efectividad del tratamiento, posibles efectos adversos y con el orden de administración del fármaco anti-TNFα. Evaluar los factores predictores de aparición de ANA y de enfermedades autoinmunes. Métodos Estudio retrospectivo sobre una cohorte de 121 pacientes seguidos en un período de 11 años. Se determinaron los ANA (si fueran positivos), también se investigaron los anticuerpos anti-ADN de doble cadena y los anticuerpos extraíbles del núcleo basales a los 3, 6, 12 meses (admitiendo en el estudio a aquellos pacientes con una determinación basal y otra durante el primer año) y posteriormente cada año. En cada consulta se calculó el Psoriasis area and severity index y se recogieron los posibles efectos adversos. Resultados Durante el tratamiento de la psoriasis moderada-grave con adalimumab y etanercept se produce un aumento significativo en la positivización de los ANA, no acompañada del desarrollo de enfermedades autoinmunes. No se observa correlación con la efectividad del tratamiento, el orden cronológico de utilización de los fármacos anti-TNFα ni, aparentemente, con la aparición de efectos adversos. No se demuestran factores predictores del desarrollo de ANA excepto el índice de masa corporal. Conclusión Recomendamos la determinación de ANA y el despistaje de enfermedades autoinumnes previos al tratamiento con fármacos anti-TNFα, pero no una determinación seriada y rutinaria durante el seguimiento, excepto en aquellos casos en los que existan signos o síntomas de sospecha de enfermedad autoinmune. Background The induction of antinuclear antibodies (ANA) and the onset of autoimmune diseases have been reported after treatment with tumor necrosis factor (TNF) inhibitors, though controversy persists. Objectives To determine the frequency of onset of autoimmune diseases and of the appearance of autoantibodies in psoriasis patients administered TNF inhibitors (adalimumab and etanercept) subcutaneously and to correlate this with the effectiveness of treatment, adverse effects, and the order of use of TNF inhibitors. We also tried to identify any factors that might predict the appearance of ANA and autimmune diseases. Methods We performed a retrospective study of a cohort of 121 patients monitored over an 11-year period. ANA were measured at baseline and at 3, 6, and 12 months; positive results were followed up by study of antibodies to double-stranded DNA. Extractable nuclear antigen (ENA) antibodies were also studied at baseline and at 3, 6, and 12 months. Patients with a baseline assay of ANA and ENA at least one more assay during the first year were included in the study, and these antibodies were measured annually thereafter. Psoriasis area severity index was calculated and adverse effects were recorded at each visit.
      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2016.12.014
       
  • Angiosarcoma cutáneo: estudio clínico-patológico de 16
           casos
    • Authors: C. Requena; E. Sendra; B. Llombart; O. Sanmartín; C. Guillén; J. Lavernia; V. Traves; J. Cruz
      Pages: 457 - 465
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): C. Requena, E. Sendra, B. Llombart, O. Sanmartín, C. Guillén, J. Lavernia, V. Traves, J. Cruz
      Introducción y objetivos El angiosarcoma primario cutáneo es uno de los tumores más agresivos y de peor pronóstico de la piel. Su clínica inicialmente indolente justifica frecuentes diagnósticos tardíos, lo que sumado a su carácter muchas veces multifocal y a su mala delimitación suele dificultar la cirugía. Debido a su baja frecuencia existen pocas series largas de casos tratados en un mismo centro. Revisamos las características clínico-patológicas de los angiosarcomas cutáneos tratados en nuestro centro en búsqueda de factores pronósticos, así como de posibles rasgos que faciliten un diagnóstico precoz. Material y métodos Se realizó un estudio observacional retrospectivo de todos los pacientes diagnosticados de angiosarcoma cutáneo atendidos en nuestro hospital entre enero de 2000 y diciembre de 2015. Se recogieron 16 parámetros clínicos incluidos —entre otros— edad, sexo, tipo de angiosarcoma, localización, tamaño, tiempo de evolución y además 8 parámetros histopatológicos. Resultados Se recogieron 16 pacientes con angiosarcoma cutáneo —11 mujeres y 5 varones—, la media de edad fue de 67 años y la mediana de 71 años. La localización más frecuente fue el tronco con 10 casos, seguida de la cabeza y el cuello con 5 casos. La media del tamaño tumoral fue de 10cm y la mediana de 6,5cm. Se realizó escisión quirúrgica del tumor a 14 pacientes. Tras una media de seguimiento de 42,5 meses, 6 de los 16 pacientes seguían vivos al finalizar el estudio. Conclusiones La supervivencia de los pacientes con angiosarcoma cutáneo viene determinada principalmente por el tamaño tumoral y la edad. Otros rasgos asociados a peor pronóstico en nuestros pacientes fueron la infiltración a planos más profundos (músculo), un patrón histológico predominantemente sólido y un mayor número de mitosis. Introduction and objectives Primary cutaneous angiosarcoma is one of the most aggressive skin tumors and carries a very poor prognosis. Its initially indolent clinical presentation explains the frequently late diagnosis that, together with its typically multifocal pattern and poor delimitation, often makes surgery difficult. The low incidence of primary cutaneous angiosarcoma means that few large single-center series have been published. We review the clinical and pathologic characteristics of cutaneous angiosarcomas treated in our hospital, looking for prognostic factors and for possible diagnostic traits that could facilitate early diagnosis. Material and methods This was a retrospective observational study including all patients diagnosed with cutaneous angiosarcoma in Instituto Valenciano de Oncología in Valencia, Spain between January 2000 and December 2015. We recorded 16 clinical parameters, including age, sex, type of angiosarcoma, site, size, and time since diagnosis, and 8 histopathologic parameters. Results We identified 16 patients (11 women and 5 men) with cutaneous angiosarcoma. Their mean age was 67 years (median, 71 years). The most common site was the trunk (10 cases), followed by the head and neck (5 cases). The mean size of the tumor was 10cm (median, 6.5cm). Fourteen patients underwent surgical excision. Six of the 16 patients were alive at the end of the study, after a mean follow-up period of 42.5 months.
      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2017.01.014
       
  • Nódulo umbilical congénito en paciente de un año
    • Authors: R. Pérez-Mesonero; V. Melgar-Molero; A. Martín-Fuentes
      Pages: 467 - 468
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): R. Pérez-Mesonero, V. Melgar-Molero, A. Martín-Fuentes


      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2016.05.020
       
  • Horizontal melanonychia
    • Authors: A. Salman; A. Eser; I. Kaygusuz Atagunduz; T. Ergun
      Pages: 469 - 470
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): A. Salman, A. Eser, I. Kaygusuz Atagunduz, T. Ergun


      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2016.01.014
       
  • FR-Dermatosis neutrofílicas de las manos: ¿diferentes denominaciones
           para un mismo cuadro clínico'
    • Authors: F. Tous-Romero; M. Prieto-Barrios; V. Velasco-Tamariz; S. Burillo-Martínez
      Pages: 471 - 472
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): F. Tous-Romero, M. Prieto-Barrios, V. Velasco-Tamariz, S. Burillo-Martínez


      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2016.12.010
       
  • Melanoma glúteo gigante
    • Authors: A. Abascal Amo; E. Torres Mínguez; M. Marín Gutzke
      First page: 473
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): A. Abascal Amo, E. Torres Mínguez, M. Marín Gutzke


      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2016.02.019
       
  • Placa eritematosa en pliegue perianal de años de evolución
    • Authors: I. Pérez-López; G. Blasco-Morente; A. Martínez-López; S. Arias-Santiago
      First page: 474
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): I. Pérez-López, G. Blasco-Morente, A. Martínez-López, S. Arias-Santiago


      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2015.12.015
       
  • Hemangioma infantil de crecimiento mínimo o detenido segmentario en
           un síndrome LUMBAR
    • Authors: X. Calderón-Castrat; J. Peceros-Escalante; F. Velásquez; R.M. Lipa-Chancolla; R. Ballona
      Pages: 475 - 477
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): X. Calderón-Castrat, J. Peceros-Escalante, F. Velásquez, R.M. Lipa-Chancolla, R. Ballona


      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2016.10.003
       
  • Parafinoma de pene: ¿le hacemos una ecografía'
    • Authors: C. Morales-Raya; A. Calleja-Algarra; F. Tous-Romero; R. Rivera-Díaz
      Pages: 478 - 480
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): C. Morales-Raya, A. Calleja-Algarra, F. Tous-Romero, R. Rivera-Díaz


      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2016.11.007
       
  • Enfermedad de Rosai-Dorfman cutánea facial
    • Authors: M.Á. Flores-Terry; G. Romero-Aguilera; L. González-López; M. García-Arpa
      Pages: 480 - 482
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): M.Á. Flores-Terry, G. Romero-Aguilera, L. González-López, M. García-Arpa


      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2016.10.018
       
  • Onicomicosis subungueal proximal por Aspergillus niger: un simulador de
           melanoma maligno subungueal
    • Authors: M. Álvarez-Salafranca; S. Hernández-Ostiz; S. Salvo Gonzalo; M. Ara Martín
      Pages: 482 - 485
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): M. Álvarez-Salafranca, S. Hernández-Ostiz, S. Salvo Gonzalo, M. Ara Martín


      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2016.11.002
       
  • Morfea en una paciente con psoriasis en tratamiento con ustekinumab:
           ¿coexistencia o efecto adverso'
    • Authors: O. Corral Magaña; J. Escalas Taberner; M.M. Escudero Góngora; A. Giacaman Contreras
      Pages: 487 - 489
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): O. Corral Magaña, J. Escalas Taberner, M.M. Escudero Góngora, A. Giacaman Contreras


      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2016.11.005
       
  • Reconstrucción del ala nasal mediante injerto condrocutáneo
    • Authors: T. Kueder-Pajares; C. Prada-García; P. Sanchez-Sambucety; M.A. Rodriguez-Prieto
      Pages: 489 - 491
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): T. Kueder-Pajares, C. Prada-García, P. Sanchez-Sambucety, M.A. Rodriguez-Prieto


      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2016.11.006
       
  • Riesgo cardiovascular en psoriasis
    • Authors: M.P.
      Abstract: Publication date: Available online 21 June 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): M.P. González García


      PubDate: 2017-06-24T07:14:46Z
       
  • La figura del Profesor Joaquín Piñol Aguadé
    • Authors: C. Herrero-Mateu
      Abstract: Publication date: Available online 20 June 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): C. Herrero-Mateu


      PubDate: 2017-06-24T07:14:46Z
      DOI: 10.1016/j.ad.2017.04.017
       
  • FR-Luces y sombras de nuevos fármacos en el tratamiento de la
           alopecia areata
    • Authors: D. Morgado-Carrasco; E. Rodríguez-Lobato; J. Riera-Monroig; J. Ferrando
      Abstract: Publication date: Available online 20 June 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): D. Morgado-Carrasco, E. Rodríguez-Lobato, J. Riera-Monroig, J. Ferrando


      PubDate: 2017-06-24T07:14:46Z
      DOI: 10.1016/j.ad.2017.05.003
       
  • Dermoscopy of Erythromelanosis Follicularis Faciei et Colli
    • Authors: E. Errichetti; S. Pizzolitto; G. Stinco
      Abstract: Publication date: Available online 16 June 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): E. Errichetti, S. Pizzolitto, G. Stinco


      PubDate: 2017-06-18T07:09:51Z
      DOI: 10.1016/j.ad.2017.04.016
       
  • Plasma rico en plaquetas en el tratamiento del fotodaño cutáneo
           en las manos
    • Authors: J.O. Cabrera-Ramírez; A.G. Puebla-Mora; A. González-Ojeda; D. García-Martínez; J.A. Cortés-Lares; A.R. Márquez-Valdés; G.I. Contreras-Hernández; J. Bracamontes-Blanco; J.A. Saucedo Ortiz; C. Fuentes-Orozco
      Abstract: Publication date: Available online 16 June 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): J.O. Cabrera-Ramírez, A.G. Puebla-Mora, A. González-Ojeda, D. García-Martínez, J.A. Cortés-Lares, A.R. Márquez-Valdés, G.I. Contreras-Hernández, J. Bracamontes-Blanco, J.A. Saucedo Ortiz, C. Fuentes-Orozco
      Introducción El plasma rico en plaquetas (PRP) aporta factores de crecimiento que inducen la síntesis de colágeno y otros componentes de la matriz extracelular, y estimula la activación de fibroblastos. El objetivo de este estudio es evaluar el efecto del PRP en el tratamiento del fotodaño en manos. Material y métodos Estudio de tipo experimental. Se incluyeron 18 pacientes con envejecimiento en el dorso de las manos, de tipo 3 en la escala de fotodaño de Glogau o de clase II de la clasificación de arrugas y elastosis de Fitzpatrick. Se aplicó PRP en la piel del dorso de las manos y se tomaron biopsias cutáneas antes y después del tratamiento para la comparación histológica. Resultados La edad media de las pacientes fue de 47,9 ± 4,3 años. El análisis histológico demostró un incremento en el número de fibroblastos (p = 0,000), número de vasos (p = 0,000) y cantidad de colágeno (p = 0,27), representado como un cambio en la escala de clasificación de arrugas y elastosis de Fitzpatrick (p < 0,001) y en la escala de fotodaño de Glogau (p = 0,01). Conclusiones El PRP indujo una reducción en los signos y síntomas del envejecimiento cutáneo, con mejoría en las arrugas y elastosis. Background Platelet-rich plasma (PRP) provides growth factors that stimulate fibroblast activation and induce the synthesis of collagen and other components of the extracellular matrix. The objective of this study was to evaluate the effect of PRP in the treatment of photodamage of the skin of the hands. Material and methods This was an experimental study. Eighteen patients with aging of the skin of the dorsum of the hands (type III of the Glogau photoaging scale or class II of the Fitzpatrick wrinkle and elastosis scale) were included. A histological comparison was made of skin biopsies taken before and after the application of PRP to the skin of the dorsum of the hands. Results The mean age of the patients was 47.9 (4.3) years. Histological analysis showed an increase in the number of fibroblasts (P<.001), number of vessels (P<.001), and collagen density (P=.27). These changes produced significant improvements in the Fitzpatrick wrinkle and elastosis scale (P<.001) and in the Glogau photoaging scale (P=.01). Conclusions PRP induced a reduction in the manifestations of skin aging, including an improvement in wrinkles and elastosis.
      Graphical abstract image

      PubDate: 2017-06-18T07:09:51Z
      DOI: 10.1016/j.ad.2017.04.006
       
  • Loxoscelismo cutáneo-visceral
    • Authors: R. Cullen; P. Hasbún; M.P. Piquer
      Abstract: Publication date: Available online 12 June 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): R. Cullen, P. Hasbún, M.P. Piquer


      PubDate: 2017-06-14T06:13:43Z
      DOI: 10.1016/j.ad.2016.12.020
       
  • Implicaciones clínicas, diagnósticas y terapéuticas de la psoriasis y
           enfermedad cardiovascular
    • Authors: C. Bonanad; E. González-Parra; R. Rivera; J.M. Carrascosa; E. Daudén; A. Olveira; R. Botella-Estrada
      Abstract: Publication date: Available online 11 June 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): C. Bonanad, E. González-Parra, R. Rivera, J.M. Carrascosa, E. Daudén, A. Olveira, R. Botella-Estrada
      En los últimos años el concepto de psoriasis como enfermedad sistémica se ha ido extendiendo debido a su asociación con múltiples comorbilidades, entre las que destaca la arterioesclerosis y la enfermedad cardiovascular. En diferentes estudios a lo largo de los años se ha demostrado que en los pacientes con psoriasis, sobre todo en aquellos más jóvenes, con formas más graves y/o artritis psoriásica, existe una mayor prevalencia de factores de riesgo y síndrome metabólico, así como un mayor riesgo de presentar eventos cardiovasculares mayores, como el infarto de miocardio, la enfermedad cerebrovascular y la arteriopatía periférica. Además, aún no queda claro cuáles de los tratamientos actuales podrían ser más beneficiosos en cuanto a reducción del riesgo cardiovascular en estos pacientes. Por eso, es importante la difusión entre dermatólogos de este riesgo aumentado, con el fin de diagnosticar precozmente aquellos factores de riesgo modificables, y derivar al paciente a otros especialistas en el momento oportuno para prevenir el desarrollo de eventos cardiovasculares mayores. In recent years the concept of psoriasis as a systemic disease has gained acceptance due to its association with numerous comorbid conditions, particularly atherosclerosis and cardiovascular disease. Several studies have shown that patients with psoriasis, especially younger patients and those with more severe forms of psoriasis or with psoriatic arthritis, have a higher prevalence of risk factors and metabolic syndrome, as well as an increased risk of major cardiovascular events such as myocardial infarction, cerebrovascular disease, and peripheral arterial disease. Furthermore, it remains unclear which of the current treatments might be more effective in reducing cardiovascular risk in these patients. It is therefore important for dermatologists to be aware of this increased risk, to be able to detect modifiable risk factors early and, when appropriate, refer patients to other specialists for the prevention of major cardiovascular events.

      PubDate: 2017-06-14T06:13:43Z
      DOI: 10.1016/j.ad.2016.12.023
       
  • Antecedentes históricos de las úlceras venosas crónicas
    • Authors: A. Imbernón-Moya; F.J. Ortiz-de Frutos; M. Sanjuan-Alvarez; I. Portero-Sanchez
      Abstract: Publication date: Available online 10 June 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): A. Imbernón-Moya, F.J. Ortiz-de Frutos, M. Sanjuan-Alvarez, I. Portero-Sanchez


      PubDate: 2017-06-14T06:13:43Z
      DOI: 10.1016/j.ad.2017.04.010
       
  • Liquen plano palmoplantar: espectro de manifestaciones clínicas en un
           paciente
    • Authors: S. Burillo-Martínez; F. Tous-Romero; J.L. Rodríguez-Peralto; C. Postigo-Llorente
      Abstract: Publication date: Available online 10 June 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): S. Burillo-Martínez, F. Tous-Romero, J.L. Rodríguez-Peralto, C. Postigo-Llorente


      PubDate: 2017-06-14T06:13:43Z
      DOI: 10.1016/j.ad.2017.01.019
       
  • Histiocitosis de células indeterminadas en edad pediátrica: a
           propósito de un caso
    • Authors: A. Sahuquillo-Torralba; M.A. Navarro-Mira; M. Llavador-Ros; R. Botella-Estrada
      Abstract: Publication date: Available online 10 June 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): A. Sahuquillo-Torralba, M.A. Navarro-Mira, M. Llavador-Ros, R. Botella-Estrada


      PubDate: 2017-06-14T06:13:43Z
      DOI: 10.1016/j.ad.2017.01.022
       
  • Hyperkeratotic lesions on legs
    • Authors: J.M. Sánchez Sánchez; J. Molinero Caturla; J.R. Ferreres Riera; R.M. Penín Mosquera
      Abstract: Publication date: Available online 3 June 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): J.M. Sánchez Sánchez, J. Molinero Caturla, J.R. Ferreres Riera, R.M. Penín Mosquera


      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2017.05.001
       
  • FR-Estudio METOP: nuevas evidencias sobre el uso del metotrexato
           subcutáneo en psoriasis
    • Authors: D. Morgado-Carrasco; X. Fustà-Novell; J. Riera Monroig; J.M. Mascaró Galy
      Abstract: Publication date: Available online 3 June 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): D. Morgado-Carrasco, X. Fustà-Novell, J. Riera Monroig, J.M. Mascaró Galy


      PubDate: 2017-06-04T04:23:54Z
      DOI: 10.1016/j.ad.2017.04.007
       
  • Exéresis en U para onicocriptosis
    • Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): M. Sánchez-Regaña


      PubDate: 2017-06-04T04:23:54Z
       
  • Angiosarcoma cutáneo: la importancia de la sospecha clínica
    • Authors: Toll
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): A. Toll


      PubDate: 2017-06-04T04:23:54Z
       
  • Hospitalización del paciente dermatológico, ¿dónde, cuándo y por
           qué'
    • Authors: Borbujo
      Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): C. Martínez-Morán, J. Borbujo


      PubDate: 2017-06-04T04:23:54Z
       
  • Tratamiento con microondas en la hiperhidrosis y bromhidrosis axilar
    • Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): I. Sánchez-Carpintero, A. Martín-Gorgojo, R. Ruiz-Rodríguez
      La hiperhidrosis axilar (HA) y la bromhidrosis son un motivo de consulta frecuente en dermatología. Hoy en día el tratamiento más indicado es la inyección de toxina botulínica, una opción muy eficaz pero con el inconveniente de su temporalidad, y en el caso de la bromhidrosis su nula eficacia. Por otra parte, la indicación de la simpatectomía cada vez se recomienda menos por la alta incidencia de hiperhidrosis compensatoria. En este artículo se expone el tratamiento de la HA y la bromhidrosis con un dispositivo novedoso de microondas, capaz de reemplazar las glándulas ecrinas y apocrinas por fibrosis, consiguiendo unos resultados posiblemente permanentes. El procedimiento debe realizarse preferiblemente con anestesia local tumescente. Los efectos secundarios son temporales, principalmente inflamación local. Su eficacia clínica y seguridad sitúan a esta técnica, avalada por estudios recientes publicados, como una alternativa de primera elección tanto para la HA como para la bromhidrosis. Axillary hyperhidrosis (AH) and bromhidrosis are common causes of consultation in dermatology. Currently, the most widely prescribed treatment for AH is botulinum toxin, a very effective but temporary option; it is totally ineffective in bromhidrosis. Sympathectomy is an increasingly infrequent choice of treatment due to the high incidence of compensatory hyperhidrosis. We describe the treatment of AH and bromhidrosis with a novel microwave device that can fibrose eccrine and apocrine glands, achieving possibly permanent results. The procedure should preferably be performed under tumescent anesthesia. Side effects, principally local inflammation, are transient. Clinical effectiveness and safety, supported by recently published studies, position this technique as a first-choice option both for hyperhidrosis and for bromhidrosis.

      PubDate: 2017-06-04T04:23:54Z
       
  • Seudotumor xantomatoso diferido tras tratamiento de cáncer de mama
    • Abstract: Publication date: June 2017
      Source:Actas Dermo-Sifiliográficas, Volume 108, Issue 5
      Author(s): M. González-Sabín, S. Mallo-García, E. Rodríguez-Díaz, P. Gonzalvo-Rodríguez


      PubDate: 2017-06-04T04:23:54Z
       
  • Ivermectina oral: recuperando un fármaco para el tratamiento de la
           escabiosis
    • Authors: G. Blasco Morente
      Abstract: Publication date: Available online 26 May 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): G. Blasco Morente


      PubDate: 2017-05-30T03:34:46Z
      DOI: 10.1016/j.ad.2017.04.008
       
  • Successful short desensitization treatment protocol with narrowband UVB
           phototherapy (TL-01) in polymorphic light eruption
    • Authors: A. Combalia; C. Fernández-Sartorio; X. Fustà; D. Morgado-Carrasco; S. Podlipnik; P. Aguilera
      Abstract: Publication date: Available online 23 May 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): A. Combalia, C. Fernández-Sartorio, X. Fustà, D. Morgado-Carrasco, S. Podlipnik, P. Aguilera
      Introduction Polymorphic light eruption (PLE) is a common idiopathic photodermatosis that typically presents with pruritic papular or papulovesicular lesions on sun-exposed skin between spring and autumn. In many subjects PLE is mild, and can usually be prevented by the use of broad-spectrum topical sunscreens and a gradual increase in sunlight exposure. However, in some individuals, sunlight exposure results in florid PLE and they often benefit from prophylactic desensitization treatment using phototherapy in early spring, an artificial method that induces a “hardening” phenomenon. Objective To describe and evaluate the efficacy of a short desensitization protocol, based on a one-month-treatment, administered twice a week with narrow band UVB in subjects with severe polymorphic light eruption (PLE). Methods A retrospective, open planned and non-randomized study to assess the efficacy of UVB phototherapy in prevention of polymorphic light eruption. Results Fifteen subjects diagnosed with severe PLE were treated with the standard protocol in our Photobiology Unit between 2014 and 2015. The effect of hardening was sustained during follow up in 87.5% of desensitization treatments. A statistically significant association (p <0.05) between the years of duration of the PLE and the response to treatment was found. Conclusions The effect of hardening was maintained in the vast majority of subjects, obtaining a good benefit with no PLE episodes during all the summer. We demonstrate that our standard protocol is effective, and produces a successful outcome for the majority of PLE subjects. Our protocol is shorter than those currently applied, being favourable both for the patient and the physician.
      Graphical abstract image

      PubDate: 2017-05-25T03:12:05Z
      DOI: 10.1016/j.ad.2017.04.004
       
  • Variabilidad en la toma de decisiones terapéuticas. A propósito de la
           evaluación de la fiabilidad de una herramienta TIC
    • Authors: F. Rivas Ruiz
      Abstract: Publication date: Available online 22 May 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): F. Rivas Ruiz


      PubDate: 2017-05-25T03:12:05Z
      DOI: 10.1016/j.ad.2017.04.009
       
  • Dermatitis granulomatosa postherpética en un paciente tratado con
           nivolumab
    • Authors: P. Martín-Carrasco; C. Pérez-Ruiz; T. de Zulueta-Dorado; J. Conejo-Mir
      Abstract: Publication date: Available online 19 May 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): P. Martín-Carrasco, C. Pérez-Ruiz, T. de Zulueta-Dorado, J. Conejo-Mir


      PubDate: 2017-05-20T02:50:47Z
      DOI: 10.1016/j.ad.2017.02.016
       
  • Novedades en inmunología del melanoma
    • Authors: I. Escandell; J.M. Martín; E. Jordá
      Abstract: Publication date: Available online 18 May 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): I. Escandell, J.M. Martín, E. Jordá
      Desde la introducción de la inmunoterapia el tratamiento del melanoma ha sufrido una revolución, consiguiéndose cifras de supervivencia superiores a las que se alcanzaban con los tratamientos previos. Los fármacos inmunomoduladores disponibles actualmente van dirigidos principalmente frente a las moléculas de superficie CTLA-4 y PD-1, que ejercen un efecto inhibidor sobre la respuesta inmune antitumoral. Se trata de un tratamiento en pleno proceso de expansión, y la investigación se dirige hacia el descubrimiento de nuevas moléculas, las combinaciones de los fármacos disponibles o la identificación de biomarcadores que permitan seleccionar a los pacientes idóneos para cada terapia. Approaches to treating melanoma have changed radically since the introduction of immunotherapy, and survival figures are now higher than possible with earlier therapies. The immunomodulators currently available mainly block CTLA-4 (cytotoxicT lymphocyte-associated molecule-4) and PD-1 (programed cell death protein 1) translocated to the cell surface, where they inhibit the antitumor immune response. Treatments blocking these molecules are being more widely used. Research now seeks new molecular targets, the best combinations of available drugs, and biomarkers that can identify ideal candidates for each one.
      Graphical abstract image

      PubDate: 2017-05-20T02:50:47Z
      DOI: 10.1016/j.ad.2017.01.017
       
  • Otras caras de la enfermedad de Darier
    • Authors: del Rio
      Abstract: Publication date: Available online 17 May 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): E. del Rio


      PubDate: 2017-05-20T02:50:47Z
       
  • Síndrome de CLAPO
    • Authors: Flores-Terry Zamberk-Majlis; M.P. Cortina-de Calle
      Abstract: Publication date: Available online 15 May 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): M.Á. Flores-Terry, P. Zamberk-Majlis, M.P. Cortina-de la Calle, M. García-Arpa


      PubDate: 2017-05-20T02:50:47Z
       
  • Superioridad en la detección de vasos de pequeño calibre con modo X flow
           frente al doppler convencional en la mancha en vino de Oporto. Estudio
           piloto
    • Authors: I. Salgüero Fernández; F. Alfageme Roldán; G. Roustan Gullón
      Abstract: Publication date: Available online 12 May 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): I. Salgüero Fernández, F. Alfageme Roldán, G. Roustan Gullón


      PubDate: 2017-05-15T02:47:09Z
      DOI: 10.1016/j.ad.2016.12.009
       
  • Respuesta a la réplica de Van den Reek et al. a: El análisis de
           supervivencia no es un buen método para evaluar la seguridad o la
           efectividad de los tratamientos sistémicos en psoriasis
    • Abstract: Publication date: Available online 12 May 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): P. Dávila-Seijo, I. García-Doval


      PubDate: 2017-05-15T02:47:09Z
       
  • FR - Nevus melanocíticos eruptivos asociados a medicamentos
    • Authors: P. García-Montero; J.F. Millán-Cayetano; C. García-Harana; J. del Boz
      Abstract: Publication date: Available online 12 May 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): P. García-Montero, J.F. Millán-Cayetano, C. García-Harana, J. del Boz


      PubDate: 2017-05-15T02:47:09Z
      DOI: 10.1016/j.ad.2016.12.024
       
  • Obsessive Compulsive Symptoms and Quality of Life in mothers of Children
           With Atopic Dermatitis
    • Authors: S. Gunduz; E. Usak; S. Ozen; C. Gorpelioglu
      Abstract: Publication date: Available online 11 May 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): S. Gunduz, E. Usak, S. Ozen, C. Gorpelioglu
      Background and objectives Atopic dermatitis is one of the most common skin disorders in children and it can negatively affect both children and their families. The purpose of this study was to investigate the effect of atopic dermatitis on quality of life related to maternal health and maternal obsessive compulsive symptoms. Methods A cross-sectional study was conducted in the pediatric and dermatology polyclinics. The SCORAD index was used for determining the severity of disease, and the Maudsley Obsessive Compulsive Inventory (MOCI) and SF-36 form were applied to the participants’ mothers. Results A total of 120 children and their mothers participated the study. Comparing the atopic dermatitis group and the healthy control group, no statistically significant differences were seen in terms of MOCI and SF-36 scores, except for the physical functioning subscore. Conclusion The results showed that having a child with atopic dermatitis and the severity of the disease do not influence their mothers in terms of obsessive-compulsive symptoms and health-related quality of life, except for physical functioning scores.

      PubDate: 2017-05-15T02:47:09Z
      DOI: 10.1016/j.ad.2017.01.004
       
  • Radiotherapy in nonmelanoma skin cancer: Radiosensitivity, radioresistance
           and radiocurability. In regard to Gracia-Cazaña et al.
    • Authors: Vargas
      Abstract: Publication date: Available online 11 May 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): A. Vargas


      PubDate: 2017-05-15T02:47:09Z
       
  • La campaña Euromelanoma
    • Authors: J.C. Moreno Giménez
      Abstract: Publication date: Available online 9 May 2017
      Source:Actas Dermo-Sifiliográficas
      Author(s): J.C. Moreno Giménez


      PubDate: 2017-05-10T02:43:43Z
      DOI: 10.1016/j.ad.2017.03.005
       
 
 
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