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Publisher: Elsevier   (Total: 3031 journals)

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Showing 1 - 200 of 3031 Journals sorted alphabetically
AASRI Procedia     Open Access   (Followers: 15)
Academic Pediatrics     Hybrid Journal   (Followers: 20, SJR: 1.402, h-index: 51)
Academic Radiology     Hybrid Journal   (Followers: 16, SJR: 1.008, h-index: 75)
Accident Analysis & Prevention     Partially Free   (Followers: 79, SJR: 1.109, h-index: 94)
Accounting Forum     Hybrid Journal   (Followers: 22, SJR: 0.612, h-index: 27)
Accounting, Organizations and Society     Hybrid Journal   (Followers: 27, SJR: 2.515, h-index: 90)
Achievements in the Life Sciences     Open Access   (Followers: 4)
Acta Anaesthesiologica Taiwanica     Open Access   (Followers: 5, SJR: 0.338, h-index: 19)
Acta Astronautica     Hybrid Journal   (Followers: 303, SJR: 0.726, h-index: 43)
Acta Automatica Sinica     Full-text available via subscription   (Followers: 3)
Acta Biomaterialia     Hybrid Journal   (Followers: 25, SJR: 2.02, h-index: 104)
Acta Colombiana de Cuidado Intensivo     Full-text available via subscription  
Acta de Investigación Psicológica     Open Access   (Followers: 2)
Acta Ecologica Sinica     Open Access   (Followers: 8, SJR: 0.172, h-index: 29)
Acta Haematologica Polonica     Free   (SJR: 0.123, h-index: 8)
Acta Histochemica     Hybrid Journal   (Followers: 3, SJR: 0.604, h-index: 38)
Acta Materialia     Hybrid Journal   (Followers: 196, SJR: 3.683, h-index: 202)
Acta Mathematica Scientia     Full-text available via subscription   (Followers: 5, SJR: 0.615, h-index: 21)
Acta Mechanica Solida Sinica     Full-text available via subscription   (Followers: 9, SJR: 0.442, h-index: 21)
Acta Oecologica     Hybrid Journal   (Followers: 9, SJR: 0.915, h-index: 53)
Acta Otorrinolaringologica (English Edition)     Full-text available via subscription   (Followers: 1)
Acta Otorrinolaringológica Española     Full-text available via subscription   (Followers: 3, SJR: 0.311, h-index: 16)
Acta Pharmaceutica Sinica B     Open Access   (Followers: 2)
Acta Poética     Open Access   (Followers: 4)
Acta Psychologica     Hybrid Journal   (Followers: 21, SJR: 1.365, h-index: 73)
Acta Sociológica     Open Access  
Acta Tropica     Hybrid Journal   (Followers: 5, SJR: 1.059, h-index: 77)
Acta Urológica Portuguesa     Open Access  
Actas Dermo-Sifiliograficas     Full-text available via subscription   (Followers: 4)
Actas Dermo-Sifiliográficas (English Edition)     Full-text available via subscription   (Followers: 3)
Actas Urológicas Españolas     Full-text available via subscription   (Followers: 3, SJR: 0.383, h-index: 19)
Actas Urológicas Españolas (English Edition)     Full-text available via subscription   (Followers: 2)
Actualites Pharmaceutiques     Full-text available via subscription   (Followers: 5, SJR: 0.141, h-index: 3)
Actualites Pharmaceutiques Hospitalieres     Full-text available via subscription   (Followers: 4, SJR: 0.112, h-index: 2)
Acupuncture and Related Therapies     Hybrid Journal   (Followers: 4)
Ad Hoc Networks     Hybrid Journal   (Followers: 11, SJR: 0.967, h-index: 57)
Addictive Behaviors     Hybrid Journal   (Followers: 15, SJR: 1.514, h-index: 92)
Addictive Behaviors Reports     Open Access   (Followers: 5)
Additive Manufacturing     Hybrid Journal   (Followers: 7, SJR: 1.039, h-index: 5)
Additives for Polymers     Full-text available via subscription   (Followers: 20)
Advanced Drug Delivery Reviews     Hybrid Journal   (Followers: 119, SJR: 5.2, h-index: 222)
Advanced Engineering Informatics     Hybrid Journal   (Followers: 11, SJR: 1.265, h-index: 53)
Advanced Powder Technology     Hybrid Journal   (Followers: 16, SJR: 0.739, h-index: 33)
Advances in Accounting     Hybrid Journal   (Followers: 8, SJR: 0.299, h-index: 15)
Advances in Agronomy     Full-text available via subscription   (Followers: 15, SJR: 2.071, h-index: 82)
Advances in Anesthesia     Full-text available via subscription   (Followers: 24, SJR: 0.169, h-index: 4)
Advances in Antiviral Drug Design     Full-text available via subscription   (Followers: 3)
Advances in Applied Mathematics     Full-text available via subscription   (Followers: 6, SJR: 1.054, h-index: 35)
Advances in Applied Mechanics     Full-text available via subscription   (Followers: 10, SJR: 0.801, h-index: 26)
Advances in Applied Microbiology     Full-text available via subscription   (Followers: 21, SJR: 1.286, h-index: 49)
Advances In Atomic, Molecular, and Optical Physics     Full-text available via subscription   (Followers: 16, SJR: 3.31, h-index: 42)
Advances in Biological Regulation     Hybrid Journal   (Followers: 4, SJR: 2.277, h-index: 43)
Advances in Botanical Research     Full-text available via subscription   (Followers: 3, SJR: 0.619, h-index: 48)
Advances in Cancer Research     Full-text available via subscription   (Followers: 26, SJR: 2.215, h-index: 78)
Advances in Carbohydrate Chemistry and Biochemistry     Full-text available via subscription   (Followers: 9, SJR: 0.9, h-index: 30)
Advances in Catalysis     Full-text available via subscription   (Followers: 5, SJR: 2.139, h-index: 42)
Advances in Cellular and Molecular Biology of Membranes and Organelles     Full-text available via subscription   (Followers: 12)
Advances in Chemical Engineering     Full-text available via subscription   (Followers: 24, SJR: 0.183, h-index: 23)
Advances in Child Development and Behavior     Full-text available via subscription   (Followers: 10, SJR: 0.665, h-index: 29)
Advances in Chronic Kidney Disease     Full-text available via subscription   (Followers: 8, SJR: 1.268, h-index: 45)
Advances in Clinical Chemistry     Full-text available via subscription   (Followers: 28, SJR: 0.938, h-index: 33)
Advances in Colloid and Interface Science     Full-text available via subscription   (Followers: 18, SJR: 2.314, h-index: 130)
Advances in Computers     Full-text available via subscription   (Followers: 16, SJR: 0.223, h-index: 22)
Advances in Developmental Biology     Full-text available via subscription   (Followers: 11)
Advances in Digestive Medicine     Open Access   (Followers: 4)
Advances in DNA Sequence-Specific Agents     Full-text available via subscription   (Followers: 5)
Advances in Drug Research     Full-text available via subscription   (Followers: 22)
Advances in Ecological Research     Full-text available via subscription   (Followers: 39, SJR: 3.25, h-index: 43)
Advances in Engineering Software     Hybrid Journal   (Followers: 25, SJR: 0.486, h-index: 10)
Advances in Experimental Biology     Full-text available via subscription   (Followers: 7)
Advances in Experimental Social Psychology     Full-text available via subscription   (Followers: 38, SJR: 5.465, h-index: 64)
Advances in Exploration Geophysics     Full-text available via subscription   (Followers: 3)
Advances in Fluorine Science     Full-text available via subscription   (Followers: 8)
Advances in Food and Nutrition Research     Full-text available via subscription   (Followers: 41, SJR: 0.674, h-index: 38)
Advances in Fuel Cells     Full-text available via subscription   (Followers: 14)
Advances in Genetics     Full-text available via subscription   (Followers: 15, SJR: 2.558, h-index: 54)
Advances in Genome Biology     Full-text available via subscription   (Followers: 11)
Advances in Geophysics     Full-text available via subscription   (Followers: 6, SJR: 2.325, h-index: 20)
Advances in Heat Transfer     Full-text available via subscription   (Followers: 18, SJR: 0.906, h-index: 24)
Advances in Heterocyclic Chemistry     Full-text available via subscription   (Followers: 8, SJR: 0.497, h-index: 31)
Advances in Human Factors/Ergonomics     Full-text available via subscription   (Followers: 22)
Advances in Imaging and Electron Physics     Full-text available via subscription   (Followers: 2, SJR: 0.396, h-index: 27)
Advances in Immunology     Full-text available via subscription   (Followers: 33, SJR: 4.152, h-index: 85)
Advances in Inorganic Chemistry     Full-text available via subscription   (Followers: 9, SJR: 1.132, h-index: 42)
Advances in Insect Physiology     Full-text available via subscription   (Followers: 3, SJR: 1.274, h-index: 27)
Advances in Integrative Medicine     Hybrid Journal   (Followers: 4)
Advances in Intl. Accounting     Full-text available via subscription   (Followers: 4)
Advances in Life Course Research     Hybrid Journal   (Followers: 7, SJR: 0.764, h-index: 15)
Advances in Lipobiology     Full-text available via subscription   (Followers: 1)
Advances in Magnetic and Optical Resonance     Full-text available via subscription   (Followers: 8)
Advances in Marine Biology     Full-text available via subscription   (Followers: 16, SJR: 1.645, h-index: 45)
Advances in Mathematics     Full-text available via subscription   (Followers: 10, SJR: 3.261, h-index: 65)
Advances in Medical Sciences     Hybrid Journal   (Followers: 5, SJR: 0.489, h-index: 25)
Advances in Medicinal Chemistry     Full-text available via subscription   (Followers: 5)
Advances in Microbial Physiology     Full-text available via subscription   (Followers: 4, SJR: 1.44, h-index: 51)
Advances in Molecular and Cell Biology     Full-text available via subscription   (Followers: 21)
Advances in Molecular and Cellular Endocrinology     Full-text available via subscription   (Followers: 10)
Advances in Molecular Toxicology     Full-text available via subscription   (Followers: 6, SJR: 0.324, h-index: 8)
Advances in Nanoporous Materials     Full-text available via subscription   (Followers: 3)
Advances in Oncobiology     Full-text available via subscription   (Followers: 3)
Advances in Organometallic Chemistry     Full-text available via subscription   (Followers: 15, SJR: 2.885, h-index: 45)
Advances in Parallel Computing     Full-text available via subscription   (Followers: 7, SJR: 0.148, h-index: 11)
Advances in Parasitology     Full-text available via subscription   (Followers: 7, SJR: 2.37, h-index: 73)
Advances in Pediatrics     Full-text available via subscription   (Followers: 20, SJR: 0.4, h-index: 28)
Advances in Pharmaceutical Sciences     Full-text available via subscription   (Followers: 14)
Advances in Pharmacology     Full-text available via subscription   (Followers: 13, SJR: 1.718, h-index: 58)
Advances in Physical Organic Chemistry     Full-text available via subscription   (Followers: 7, SJR: 0.384, h-index: 26)
Advances in Phytomedicine     Full-text available via subscription  
Advances in Planar Lipid Bilayers and Liposomes     Full-text available via subscription   (Followers: 3, SJR: 0.248, h-index: 11)
Advances in Plant Biochemistry and Molecular Biology     Full-text available via subscription   (Followers: 8)
Advances in Plant Pathology     Full-text available via subscription   (Followers: 5)
Advances in Porous Media     Full-text available via subscription   (Followers: 4)
Advances in Protein Chemistry     Full-text available via subscription   (Followers: 18)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 17, SJR: 1.5, h-index: 62)
Advances in Psychology     Full-text available via subscription   (Followers: 56)
Advances in Quantum Chemistry     Full-text available via subscription   (Followers: 5, SJR: 0.478, h-index: 32)
Advances in Radiation Oncology     Open Access  
Advances in Small Animal Medicine and Surgery     Hybrid Journal   (Followers: 1, SJR: 0.1, h-index: 2)
Advances in Space Research     Full-text available via subscription   (Followers: 332, SJR: 0.606, h-index: 65)
Advances in Structural Biology     Full-text available via subscription   (Followers: 7)
Advances in Surgery     Full-text available via subscription   (Followers: 6, SJR: 0.823, h-index: 27)
Advances in the Study of Behavior     Full-text available via subscription   (Followers: 28, SJR: 1.321, h-index: 56)
Advances in Veterinary Medicine     Full-text available via subscription   (Followers: 14)
Advances in Veterinary Science and Comparative Medicine     Full-text available via subscription   (Followers: 12)
Advances in Virus Research     Full-text available via subscription   (Followers: 5, SJR: 1.878, h-index: 68)
Advances in Water Resources     Hybrid Journal   (Followers: 42, SJR: 2.408, h-index: 94)
Aeolian Research     Hybrid Journal   (Followers: 5, SJR: 0.973, h-index: 22)
Aerospace Science and Technology     Hybrid Journal   (Followers: 303, SJR: 0.816, h-index: 49)
AEU - Intl. J. of Electronics and Communications     Hybrid Journal   (Followers: 8, SJR: 0.318, h-index: 36)
African J. of Emergency Medicine     Open Access   (Followers: 4, SJR: 0.344, h-index: 6)
Ageing Research Reviews     Hybrid Journal   (Followers: 7, SJR: 3.289, h-index: 78)
Aggression and Violent Behavior     Hybrid Journal   (Followers: 388, SJR: 1.385, h-index: 72)
Agri Gene     Hybrid Journal  
Agricultural and Forest Meteorology     Hybrid Journal   (Followers: 15, SJR: 2.18, h-index: 116)
Agricultural Systems     Hybrid Journal   (Followers: 29, SJR: 1.275, h-index: 74)
Agricultural Water Management     Hybrid Journal   (Followers: 36, SJR: 1.546, h-index: 79)
Agriculture and Agricultural Science Procedia     Open Access  
Agriculture and Natural Resources     Open Access   (Followers: 1)
Agriculture, Ecosystems & Environment     Hybrid Journal   (Followers: 48, SJR: 1.879, h-index: 120)
Ain Shams Engineering J.     Open Access   (Followers: 5, SJR: 0.434, h-index: 14)
Air Medical J.     Hybrid Journal   (Followers: 3, SJR: 0.234, h-index: 18)
AKCE Intl. J. of Graphs and Combinatorics     Open Access   (SJR: 0.285, h-index: 3)
Alcohol     Hybrid Journal   (Followers: 9, SJR: 0.922, h-index: 66)
Alcoholism and Drug Addiction     Open Access   (Followers: 5)
Alergologia Polska : Polish J. of Allergology     Full-text available via subscription   (Followers: 1)
Alexandria Engineering J.     Open Access   (Followers: 1, SJR: 0.436, h-index: 12)
Alexandria J. of Medicine     Open Access  
Algal Research     Partially Free   (Followers: 7, SJR: 2.05, h-index: 20)
Alkaloids: Chemical and Biological Perspectives     Full-text available via subscription   (Followers: 3)
Allergologia et Immunopathologia     Full-text available via subscription   (Followers: 1, SJR: 0.46, h-index: 29)
Allergology Intl.     Open Access   (Followers: 5, SJR: 0.776, h-index: 35)
ALTER - European J. of Disability Research / Revue Européenne de Recherche sur le Handicap     Full-text available via subscription   (Followers: 6, SJR: 0.158, h-index: 9)
Alzheimer's & Dementia     Hybrid Journal   (Followers: 45, SJR: 4.289, h-index: 64)
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring     Open Access   (Followers: 5)
Alzheimer's & Dementia: Translational Research & Clinical Interventions     Open Access   (Followers: 3)
American Heart J.     Hybrid Journal   (Followers: 45, SJR: 3.157, h-index: 153)
American J. of Cardiology     Hybrid Journal   (Followers: 47, SJR: 2.063, h-index: 186)
American J. of Emergency Medicine     Hybrid Journal   (Followers: 34, SJR: 0.574, h-index: 65)
American J. of Geriatric Pharmacotherapy     Full-text available via subscription   (Followers: 6, SJR: 1.091, h-index: 45)
American J. of Geriatric Psychiatry     Hybrid Journal   (Followers: 14, SJR: 1.653, h-index: 93)
American J. of Human Genetics     Hybrid Journal   (Followers: 32, SJR: 8.769, h-index: 256)
American J. of Infection Control     Hybrid Journal   (Followers: 25, SJR: 1.259, h-index: 81)
American J. of Kidney Diseases     Hybrid Journal   (Followers: 31, SJR: 2.313, h-index: 172)
American J. of Medicine     Hybrid Journal   (Followers: 48, SJR: 2.023, h-index: 189)
American J. of Medicine Supplements     Full-text available via subscription   (Followers: 3)
American J. of Obstetrics and Gynecology     Hybrid Journal   (Followers: 173, SJR: 2.255, h-index: 171)
American J. of Ophthalmology     Hybrid Journal   (Followers: 51, SJR: 2.803, h-index: 148)
American J. of Ophthalmology Case Reports     Open Access   (Followers: 2)
American J. of Orthodontics and Dentofacial Orthopedics     Full-text available via subscription   (Followers: 6, SJR: 1.249, h-index: 88)
American J. of Otolaryngology     Hybrid Journal   (Followers: 22, SJR: 0.59, h-index: 45)
American J. of Pathology     Hybrid Journal   (Followers: 23, SJR: 2.653, h-index: 228)
American J. of Preventive Medicine     Hybrid Journal   (Followers: 21, SJR: 2.764, h-index: 154)
American J. of Surgery     Hybrid Journal   (Followers: 32, SJR: 1.286, h-index: 125)
American J. of the Medical Sciences     Hybrid Journal   (Followers: 13, SJR: 0.653, h-index: 70)
Ampersand : An Intl. J. of General and Applied Linguistics     Open Access   (Followers: 5)
Anaerobe     Hybrid Journal   (Followers: 4, SJR: 1.066, h-index: 51)
Anaesthesia & Intensive Care Medicine     Full-text available via subscription   (Followers: 52, SJR: 0.124, h-index: 9)
Anaesthesia Critical Care & Pain Medicine     Full-text available via subscription   (Followers: 3)
Anales de Cirugia Vascular     Full-text available via subscription  
Anales de Pediatría     Full-text available via subscription   (Followers: 2, SJR: 0.209, h-index: 27)
Anales de Pediatría (English Edition)     Full-text available via subscription  
Anales de Pediatría Continuada     Full-text available via subscription   (SJR: 0.104, h-index: 3)
Analytic Methods in Accident Research     Hybrid Journal   (Followers: 2, SJR: 2.577, h-index: 7)
Analytica Chimica Acta     Hybrid Journal   (Followers: 38, SJR: 1.548, h-index: 152)
Analytical Biochemistry     Hybrid Journal   (Followers: 151, SJR: 0.725, h-index: 154)
Analytical Chemistry Research     Open Access   (Followers: 7, SJR: 0.18, h-index: 2)
Analytical Spectroscopy Library     Full-text available via subscription   (Followers: 10)
Anesthésie & Réanimation     Full-text available via subscription  
Anesthesiology Clinics     Full-text available via subscription   (Followers: 21, SJR: 0.421, h-index: 40)
Angiología     Full-text available via subscription   (SJR: 0.124, h-index: 9)
Angiologia e Cirurgia Vascular     Open Access  
Animal Behaviour     Hybrid Journal   (Followers: 141, SJR: 1.907, h-index: 126)
Animal Feed Science and Technology     Hybrid Journal   (Followers: 5, SJR: 1.151, h-index: 83)
Animal Reproduction Science     Hybrid Journal   (Followers: 5, SJR: 0.711, h-index: 78)
Annales d'Endocrinologie     Full-text available via subscription   (SJR: 0.394, h-index: 30)
Annales d'Urologie     Full-text available via subscription  
Annales de Cardiologie et d'Angéiologie     Full-text available via subscription   (SJR: 0.177, h-index: 13)
Annales de Chirurgie de la Main et du Membre Supérieur     Full-text available via subscription  
Annales de Chirurgie Plastique Esthétique     Full-text available via subscription   (Followers: 2, SJR: 0.354, h-index: 22)
Annales de Chirurgie Vasculaire     Full-text available via subscription   (Followers: 1)

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Journal Cover Acta Anaesthesiologica Taiwanica
  [SJR: 0.338]   [H-I: 19]   [5 followers]  Follow
    
  This is an Open Access Journal Open Access journal
   ISSN (Print) 1875-4597 - ISSN (Online) 1875-452X
   Published by Elsevier Homepage  [3031 journals]
  • Epidemiology of anaphylaxis: A retrospective cohort study in Taiwan

    • Authors: Yow-Shan Lee; Wei-Zen Sun
      Abstract: Publication date: Available online 28 February 2017
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Yow-Shan Lee, Wei-Zen Sun
      Objective Medication-induced anaphylaxis is a potentially fatal event. Little is known at present about the patterns of medication-induced anaphylaxis in Asian countries. The current study aims to examine the pattern of documented incidences of drug-associated anaphylaxis in Taiwan over a 9-year period. Methods Cases of medication-associated anaphylaxis documented in the Taiwan National Health Insurance claims database during a span of 9 years (from January, 1997 to December, 2005) encompassing approximately 23 million person-years were reviewed. The database quantifies the drugs dispensed, clinical diagnoses, and patient demographics. Results Overall, 92 reports of medication-associated anaphylaxis in 92 patients were identified with potential causative agents documented. In this group, nonsteroidal anti-inflammatory drugs (NSAIDs) and antibiotics were the main classes of medications most frequently implicated as the causative agent(s) in 89% of the cases. NSAIDs alone were implicated in 28% of cases, whereas antibiotics alone were implicated in another 28% of these cases. The use of multiple medications including either antibiotics or analgesics was documented in an additional one-third of the cases. A number of different NSAIDs including aspirin, diclofenac, ketoprofen, ketorolac, and meperidine were documented as the causative agents. Among the reported cases of antibiotics-induced anaphylaxis, cefazolin was the most frequently reported causative agent with 11 cases, followed by amoxicillin with four cases. Conclusion Antibiotics and NSAIDs were the two main classes of medications most frequently implicated in the reports of anaphylaxis in the Taiwanese population. Although this may be related to the frequent use of these medications in the Taiwanese population, the observation here does advocate for reduced combination of NSAIDs and antibiotics, and more careful patient monitoring when they are combined.

      PubDate: 2017-03-07T12:11:02Z
      DOI: 10.1016/j.aat.2016.12.003
       
  • Journeys and journals east and west

    • Authors: James L. Reynolds; Wei-Zen Sun
      Abstract: Publication date: Available online 21 January 2017
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): James L. Reynolds, Wei-Zen Sun


      PubDate: 2017-01-27T22:35:23Z
      DOI: 10.1016/j.aat.2016.12.001
       
  • Postoperative nausea and vomiting free for all: A solution from
           propofol?

    • Authors: Chuen-Chau Chang; Chih-Shung Wong
      Abstract: Publication date: Available online 13 January 2017
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Chuen-Chau Chang, Chih-Shung Wong


      PubDate: 2017-01-20T20:50:57Z
      DOI: 10.1016/j.aat.2016.12.002
       
  • Influence of perioperative nonsteroidal anti-inflammatory drugs on
           complications after gastrointestinal surgery: A meta-analysis

    • Authors: Fang Peng; Shijiang Liu; Youli Hu; Min Yu; Jing Chen; Cunming Liu
      Abstract: Publication date: Available online 12 January 2017
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Fang Peng, Shijiang Liu, Youli Hu, Min Yu, Jing Chen, Cunming Liu
      Background Nonsteroidal anti-inflammatory drugs (NSAIDs) are a key part of multimodal perioperative analgesia. This study aimed to evaluate the influence of perioperative NSAIDs application on complications after gastrointestinal surgery by using meta-analysis. Methods A systematic review of published literature was conducted by searching computerized databases including PubMed, CBM, Springer, Chinese Academic Journals, and China Info since the databases were published until June 2015. The articles and retrospective references regarding complications after gastrointestinal surgery were collected to compare postoperative complications associated with NSAIDs or other analgesics. After they were assessed by randomized controlled trials and extracted by the standard of the Jadad systematic review, the homogeneous studies were pooled using RevMan 5.3 software. The meta-analysis was performed on five postoperative complications: postoperative anastomotic leak, cardiovascular events, surgical site infection, nausea and vomiting, and intestinal obstruction. Results Twelve randomized controlled trials involving 3829 patients met the inclusion criteria. The results of meta-analyses showed the following: (1) postoperative anastomotic leak: NSAIDs (including selective and nonselective NSAIDs) increased the incidence of anastomotic leak [odds ratio (OR)=3.02, 95% confidence interval (CI): 2.16–4.23, p =0.00001]. Further results showed that nonselective NSAIDs significantly increased the incidence of anastomotic leak (OR=2.96, 95% CI: 1.99–4.42, p <0.00001), and selective NSAIDs had no significant difference as compared with the control group using other analgesics (OR=2.27, 95% CI: 0.68–7.56, p =0.18); (2) postoperative cardiovascular events: NSAIDs (selective and nonselective NSAIDs) had no difference when compared with other analgesics (OR=0.50, 95% CI: 0.23–1.12, p =0.09); (3) postoperative surgical site infection: NSAIDs (selective and nonselective NSAIDs) and other analgesics had no difference in surgical site infection (OR=0.77, 95% CI: 0.52–1.15, p =0.20); (4) postoperative nausea and vomiting: NSAIDs (selective and nonselective NSAIDs) decreased the incidence of nausea and vomiting (OR=0.53, 95% CI: 0.34–0.81, p =0.003); (5) postoperative intestinal obstruction: NSAIDs (selective and nonselective NSAIDs) decreased the incidence of intestinal obstruction (OR=0.35, 95% CI: 0.13–0.89, p =0.03). Conclusions The meta-analysis suggests that postoperative NSAIDs, especially nonselective NSAIDs, could increase the incidence of anastomotic leak. NSAIDs could decrease postoperative nausea and vomiting and intestinal obstruction, but showed no difference in cardiovascular events and surgical site infection as compared with other analgesics.

      PubDate: 2017-01-20T20:50:57Z
      DOI: 10.1016/j.aat.2016.11.002
       
  • Measuring and reducing perioperative anesthetic-related mortality: View
           from East Asia

    • Authors: James L. Reynolds; Wei-Zen Sun; Yang Chen-Hsien
      Pages: 41 - 43
      Abstract: Publication date: June 2016
      Source:Acta Anaesthesiologica Taiwanica, Volume 54, Issue 2
      Author(s): James L. Reynolds, Wei-Zen Sun, Yang Chen-Hsien


      PubDate: 2016-09-16T04:06:59Z
      DOI: 10.1016/j.aat.2016.06.004
       
  • Comparison of the Supreme and the ProSeal laryngeal mask airway in
           patients undergoing laparoscopic cholecystectomy: A randomized controlled
           trial

    • Authors: Lakesh K. Anand; Nitika Goel; Manpreet Singh; Dheeraj Kapoor
      Pages: 44 - 50
      Abstract: Publication date: Available online 19 April 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Lakesh K. Anand, Nitika Goel, Manpreet Singh, Dheeraj Kapoor
      Objective The single-use LMA Supreme (Teleflex, Inc., Wayne, PA, USA) and the LMA ProSeal (Teleflex, Inc., Wayne, PA, USA) laryngeal mask airway (LMA) have similar characteristics. To date, studies have not achieved a consensus regarding the oropharyngeal leak pressure (OLP) of the LMA Supreme and LMA ProSeal, and there is little information on their efficacy in laparoscopic cholecystectomy. This study compared the safety and efficacy of the LMA Supreme and LMA ProSeal devices in patients undergoing laparoscopic cholecystectomy. Method Eighty-four eligible consenting patients were randomly allocated to the LMA Supreme group or the LMA ProSeal group. Both groups received the standard anesthesia technique. The Supreme or ProSeal LMA was inserted, the cuff was inflated to 60 cmH2O, and the LMA position was confirmed. Anesthesia was maintained using propofol and 50% oxygen in air. A gastric tube was inserted through the drain tube of the LMA to deflate the stomach, and the first attempt success rate and insertion time were recorded. During surgery, the intra-abdominal pressure was maintained at 12 mmHg. The fiberoptic view of the larynx was determined by passing a flexible fiberoptic bronchoscope. The OLPs, success rate, insertion time, hemodynamic and respiratory parameters, and complications were recorded at different time points. Results The mean OLP was significantly lower in the LMA Supreme group than in the LMA ProSeal group (24.9 ± 5.3 cmH2O vs. 28.4 ± 5.8 cmH2O; p < 0.01). The first attempt success rate and ease of insertion grading for LMA were higher in the Supreme group. The insertion time was lower in the Supreme group than in the ProSeal group (p < 0.01). The fiberoptic view was better with the ProSeal LMA. The hemodynamic and ventilatory parameters and postoperative sore throat were comparable in both groups. Conclusion The LMA ProSeal has a higher OLP than the LMA Supreme. The success rate of first attempt insertion and ease of insertion were better for the LMA Supreme group and the insertion time was lower in the LMA Supreme group. The Supreme and ProSeal LMAs were both effective for positive pressure ventilation in laparoscopic cholecystectomy.

      PubDate: 2016-04-23T13:15:06Z
      DOI: 10.1016/j.aat.2016.03.001
       
  • Key opioid prescription concerns in cancer patients: A nationwide study

    • Authors: Chih-Peng Lin; Chih-Hung Hsu; Wen-Mei Fu; Ho-Min Chen; Ying-Hui Lee; Mei-Shu Lai; Yu-Yun Shao
      Pages: 51 - 56
      Abstract: Publication date: Available online 15 June 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Chih-Peng Lin, Chih-Hung Hsu, Wen-Mei Fu, Ho-Min Chen, Ying-Hui Lee, Mei-Shu Lai, Yu-Yun Shao
      Background Opioids are crucial in cancer pain management. We examined the nationwide prescription patterns of opioids in Taiwan cancer patients to find the potential concerns. Methods We reviewed the claims database of the National Health Insurance of Taiwan for patients diagnosed with cancer from 2003 to 2011. The use and cost of analgesics were analyzed. Opioids were classified into recommended strong opioids (morphine and transdermal fentanyl), recommended weak opioids (tramadol, buprenorphine, and codeine), and unrecommended opioids (propoxyphene, nalbuphine, and meperidine). Results We enrolled 1,424,048 patients with cancer, and ∼50% of them took analgesics. Among analgesic users, patients who used opioids increased from 48.2% in 2003 to 52.0% in 2010. Approximately 92% of the opioid use came from recommended opioids, either strong (51%) or weak opioids (41%). The ratio of the use of short-acting strong opioids to that of long-acting opioids increased from 0.41 in 2003 to 0.63 in 2011. Transdermal fentanyl accounted for > 50% of the use of strong opioids. Among weak opioids, the use of tramadol gradually increased to 71% in 2011. On average, opioids contributed to 0.79‰ of all medical expenditures and 2.94‰ of all medication costs. Conclusion The use of short-acting strong opioids increased during the study period. Instead of oral opioids, transdermal fentanyl was the most commonly used opioid among Taiwan cancer patients. The use of weak opioids, particularly tramadol, was high. These concerns should be the focus of pain management education.

      PubDate: 2016-06-18T18:09:23Z
      DOI: 10.1016/j.aat.2016.05.002
       
  • Evaluation of cardiac output by bioreactance technique in patients
           undergoing liver transplantation

    • Authors: Po-Yuan Shih; Wen-Ying Lin; Ming-Hui Hung; Ya-Jung Cheng; Kuang-Cheng Chan
      Pages: 57 - 61
      Abstract: Publication date: June 2016
      Source:Acta Anaesthesiologica Taiwanica, Volume 54, Issue 2
      Author(s): Po-Yuan Shih, Wen-Ying Lin, Ming-Hui Hung, Ya-Jung Cheng, Kuang-Cheng Chan
      Background This study compared the cardiac output (CO) obtained from PiCCO with that obtained from the noninvasive NICOM method. Methods Twenty-one cirrhotic patients receiving liver transplantation were enrolled. During the operation, their CO was measured by the PiCCO system via the thermodilution method as the standard and by the NICOM method. Two parameters including cardiac index (CI) and stroke volume index (SVI) were collected simultaneously at three phases during the surgery including the dissection phase (T1), the anhepatic phase (T2), and the reperfusion phase (T3). Correlation, Bland and Altman methods, and linear mixed model were used to evaluate the monitoring ability of both systems. Results Poor correlation was noted between the data measured by NICOM and PiCCO; the correlation coefficients for CI and SVI measured between the two systems were 0.32 and 0.39, respectively. Bland and Altman analysis showed the percentage error of CI as 63.7%, and that of SVI as 66.6% for NICOM compared to PiCCO. Using the linear mixed model, the CI and SVI measured using NICOM were significantly higher than those using PiCCO (estimated regression coefficient 0.92 and 10.77, both p < 0.001). Mixed model analysis showed no differences between the trends of CI and SVI measured by the two methods. Conclusions NICOM provided a comparable CI and SVI trend when compared to the gold standard PiCCO, but it raises concerns as an effective CO monitor because of its tendency to overestimate CI and SVI especially during the state of high cardiac output.

      PubDate: 2016-09-16T04:06:59Z
      DOI: 10.1016/j.aat.2016.06.001
       
  • Magnesium sulfate for postoperative analgesia after surgery under spinal
           anesthesia

    • Authors: Prerana N. Shah; Yamini Dhengle
      Pages: 62 - 64
      Abstract: Publication date: June 2016
      Source:Acta Anaesthesiologica Taiwanica, Volume 54, Issue 2
      Author(s): Prerana N. Shah, Yamini Dhengle
      Background Magnesium has been proven to have antinociceptive effects in animal and human models of pain. Its effect is primarily based on the regulation of calcium influx into the cell, which is natural physiological calcium antagonism and N-methyl-d-aspartate (NMDA) receptor antagonism. Methods One hundred and eight patients undergoing surgery with spinal anesthesia received either 250 mg of intravenous magnesium sulfate followed by an infusion of 500 mg magnesium sulfate (25 mg/mL) at the rate of 20 mL/hour; or the same volume of normal saline (control group) as bolus and infusion. The primary end-points in the study were to evaluate the analgesic effect and duration of sensory and motor blockade. The secondary end-points included assessment of hemodynamic effects of intravenous magnesium sulfate and rescue analgesia requirement. Results Sensory and motor blockade, respectively, were 25 minutes and 34 minutes shorter in the control group. Less patients in the magnesium group (33% vs. 53.7%) than in control group required rescue analgesia in the postoperative period. The control group required rescue analgesia nearly 3 hours earlier than the magnesium group. Only one patient in the control group experienced bradycardia. There was no event of intraoperative hypotension in either of the groups. Conclusion Intravenous magnesium sulfate when given as a bolus, followed by an infusion, delayed and decreased the need of rescue analgesics after spinal anesthesia.

      PubDate: 2016-09-16T04:06:59Z
      DOI: 10.1016/j.aat.2016.06.003
       
  • A new pharmacological role for thalidomide: Attenuation of
           morphine-induced tolerance in rats

    • Authors: Kambiz Hassanzadeh; Bashir Khodadadi; Mohammad Raman Moloudi; Hassan Amini; Mohammad Reza Rahmani; Esmael Izadpanah
      Pages: 65 - 69
      Abstract: Publication date: June 2016
      Source:Acta Anaesthesiologica Taiwanica, Volume 54, Issue 2
      Author(s): Kambiz Hassanzadeh, Bashir Khodadadi, Mohammad Raman Moloudi, Hassan Amini, Mohammad Reza Rahmani, Esmael Izadpanah
      Objective Tolerance to the analgesic effect is the main side effect of chronic administration of opioids. Several drugs have been studied to try to find agents to prevent the development of this phenomenon. In the present study we aimed to evaluate the effect of thalidomide on morphine-induced tolerance to the analgesic effect. Methods Groups of male rats were randomly rendered and received daily morphine in combination with thalidomide vehicle or thalidomide (2.5 mg/kg, 5 mg/kg, or 10 mg/kg, intraperitoneally). Nociception was measured using the plantar test apparatus. Latency time was recorded when the animal reacted to the light stimulus; licking or raising its hind paw. Treatments and evaluations continued until completion of tolerance to the analgesic effect of morphine. Results Our findings indicated that tolerance was achieved following 11 days of morphine administration, while thalidomide postponed the day of tolerance completion for 4 days (2.5 mg/kg and 5 mg/kg thalidomide) or 10 days (10 mg/kg thalidomide). Moreover, thalidomide prevented the morphine-induced shift to the right of the ED50 in the dose–response curve. Conclusion It was concluded that thalidomide attenuated the morphine-induced tolerance to the analgesic effect.

      PubDate: 2016-09-16T04:06:59Z
      DOI: 10.1016/j.aat.2016.06.002
       
  • A review of nationwide population study of organ transplantation in Taiwan

    • Authors: Hsin-I Tsai; Huang-Ping Yu
      Pages: 70 - 74
      Abstract: Publication date: Available online 8 June 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Hsin-I Tsai, Huang-Ping Yu
      Solid organ transplantation has become the therapy of choice for patients with end-stage organ disease. The frequently transplanted organs in Taiwan include liver, kidney, heart, and lung, and the success rate has improved significantly worldwide for the past decades. However, organ recipients are known to be at a higher risk of post-transplant infections and de novo cancer due to immunosuppression and oncogenic viral infections. Organ recipients are known to be at a two- to fourfold increased risk of cancer and the risks are particularly high for malignancies caused by viral infections, including post-transplant lymphoproliferative disorders via Epstein-Barr virus, Kaposi sarcoma via Kaposi sarcoma herpesvirus, anogenital cancers via human papillomavirus, and hepatocellular carcinoma via hepatitis B and C virus. Population-based cohort studies may help better understand the pattern of infection and cancer risk in transplant recipients and clarify the role of the immune system, infection, and risk factors in the development of malignancy. Improvement of surgical techniques, advancement of immunosuppressant therapy in addition to early detection and prevention of infection, and regular surveillance of de novo cancer after transplantation have become the mainstay of successful organ transplantation.

      PubDate: 2016-06-09T16:41:03Z
      DOI: 10.1016/j.aat.2016.05.003
       
  • Continuous interscalene brachial plexus block

    • Authors: Yasuhiro Morimoto
      First page: 75
      Abstract: Publication date: Available online 25 April 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Yasuhiro Morimoto


      PubDate: 2016-04-27T13:40:11Z
      DOI: 10.1016/j.aat.2016.02.002
       
  • Mirtazapine, in orodispersible form, for patients with preoperative
           psychological distress: A pilot study

    • Authors: Wei-Han Chou; Feng-Sheng Lin; Chih-Peng Lin; Wen-Ying Lin; Jr-Chi Yie; Wei-Zen Sun
      Pages: 16 - 23
      Abstract: Publication date: Available online 10 February 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Wei-Han Chou, Feng-Sheng Lin, Chih-Peng Lin, Wen-Ying Lin, Jr-Chi Yie, Wei-Zen Sun
      Background Perioperative psychological distress is associated with preoperative anxiety, depression, and postoperative pain. Mirtazapine is effective as an antidepressant, anxiolytic agent, and sleep enhancer. Moreover, mirtazapine can be made as orodispersible tablets with a fast onset for patients in nil per os status. This study is to determine whether mirtazapine can help psychologically distressed patients reduce perioperative anxiety, depression, and postoperative pain. Materials and methods Patients with preoperative psychological distress, undergoing major abdominal surgery, were inquired and assigned to two groups according to their own choice. In the treatment group, patients could choose to take orodispersible mirtazapine 30 mg at each night from Preoperative Day 0 to Postoperative Day 3. There was no other intervention in the nontreatment group. Hospital Anxiety and Depression Scale (HADS), Athens Insomnia Scale (AIS), and pain scores were accessed on the day before operation (Day 0), and on the 1st day (Day 2) and 3rd day (Day 4) after operation. We compared the HADS, AIS, and pain scores, and morphine consumptions between the two groups on a daily basis. Marginal regression models were fitted to our correlated longitudinal data alone with the generalized estimating equations method to estimate the population average effects of time-varying mirtazapine usage on the mean values of HADS, AIS, and pain scores, and daily morphine consumptions. Results From September 2007 to December 2008, 86 patients agreed to be enrolled and 79 of them completed the study. Propensity scores and multivariate analysis showed that mirtazapine reduced HADS scores of patients in 2 days. Trial results indicated that mirtazapine lowered the AIS day index and tended to decrease night index as well. Mirtazapine may reduce patients' morphine consumption, but this effect was not statistically significant (p = 0.2). Conclusion Mirtazapine helps reduce anxiety, depression, and insomnia scores for patients with perioperative psychological distress.

      PubDate: 2016-02-10T19:17:28Z
      DOI: 10.1016/j.aat.2015.12.002
       
  • Pharmacogenomics for personalized pain medicine

    • Authors: Tai-Ming Ko; Chih-Shung Wong; Jer-Yuarn Wu; Yuan-Tsong Chen
      Pages: 24 - 30
      Abstract: Publication date: Available online 11 March 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Tai-Ming Ko, Chih-Shung Wong, Jer-Yuarn Wu, Yuan-Tsong Chen
      Pharmacogenomics aims to unravel the way that human genetic variation affects drug efficacy and toxicity. Genome-wide association studies and candidate gene findings suggest that genetic approaches may help choose the most appropriate drug and dosage while preventing adverse drug reactions (ADRs). Pain is an unpleasant feeling that usually results from tissue damage. The management of different types of pain (acute, chronic, inflammatory, neuropathic, or cancer) is challenging. Currently, drug intervention is the first-line therapy for resolving pain. However, differences in drug efficacy between individuals are common with pain medications. Moreover, some patients experience ADRs after being treated with specific pain drugs. This review discusses the use of drugs for pain management in the context of the recent pharmacogenomic studies on ADRs and drug efficacy.

      PubDate: 2016-03-14T00:35:09Z
      DOI: 10.1016/j.aat.2016.02.001
       
  • A novel technique to prevent damage to inflation tube of the cuffed
           endotracheal tube during air-QTM guided intubation

    • Authors: Renu Sinha; Kanil Ranjith Kumar; Ravindran Chandiran
      Pages: 33 - 34
      Abstract: Publication date: Available online 2 January 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Renu Sinha, Kanil Ranjith Kumar, Ravindran Chandiran


      PubDate: 2016-01-04T11:20:28Z
      DOI: 10.1016/j.aat.2015.12.001
       
  • Subcutaneous emphysema and pneumothorax secondary to subclavian vein
           catheterization via supraclavicular approach

    • Authors: Chih-Dou Chou; Yu-Chi Tsung; Fwu-Lin Yang
      Pages: 35 - 36
      Abstract: Publication date: Available online 6 January 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Chih-Dou Chou, Yu-Chi Tsung, Fwu-Lin Yang


      PubDate: 2016-01-08T13:54:57Z
      DOI: 10.1016/j.aat.2015.12.003
       
  • Incidence of postoperative nausea and vomiting following gynecological
           laparoscopy: A comparison of standard anesthetic technique and propofol
           infusion

    • Authors: Pradipta Bhakta; Bablu Rani Ghosh; Umesh Singh; Preeti S. Govind; Abhinav Gupta; Kulwant Singh Kapoor; Rajesh Kumar Jain; Tulsi Nag; Dipanwita Mitra; Manjushree Ray; Vikash Singh; Gauri Mukherjee
      Abstract: Publication date: Available online 23 December 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Pradipta Bhakta, Bablu Rani Ghosh, Umesh Singh, Preeti S. Govind, Abhinav Gupta, Kulwant Singh Kapoor, Rajesh Kumar Jain, Tulsi Nag, Dipanwita Mitra, Manjushree Ray, Vikash Singh, Gauri Mukherjee
      Objective To determine the safety, efficacy, and feasibility of propofol-based anesthesia in gynecological laparoscopies in reducing incidences of postoperative nausea and vomiting compared to a standard anesthesia using thiopentone/isoflurane. Design Randomized single-blind (for anesthesia techniques used) and double-blind (for postoperative assessment) controlled trial. Setting Operation theater, postanesthesia recovery room, teaching hospital. Patients Sixty ASA (American Society of Anesthesiologists) I and II female patients (aged 20–60 years) scheduled for gynecological laparoscopy were included in the study. Interventions Patients in Group A received standard anesthesia with thiopentone for induction and maintenance with isoflurane–fentanyl, and those in Group B received propofol for induction and maintenance along with fentanyl. All patients received nitrous oxide, vecuronium, and neostigmine/glycopyrrolate. No patient received elective preemptive antiemetic, but patients did receive it after more than one episode of vomiting. Measurements Assessment for incidence of postoperative nausea and vomiting as well as other recovery parameters were carried out over a period of 24 hours. Main Results Six patients (20%) in Group A and seven patients (23.3%) in Group B experienced nausea. Two patients (6.66%) in Group B had vomiting versus 12 (40%) in Group A (p <0.05). Overall, the incidence of emesis was 60% and 30% in Groups A and B, respectively (p <0.05). All patients in Group B had significantly faster recovery compared with those in Group A. No patient had any overt cardiorespiratory complications. Conclusion Propofol-based anesthesia was associated with significantly less postoperative vomiting and faster recovery compared to standard anesthesia in patients undergoing gynecological laparoscopy.

      PubDate: 2016-12-27T13:43:16Z
      DOI: 10.1016/j.aat.2016.10.002
       
  • Quadratus lumborum block intramuscular approach for pediatric surgery

    • Authors: Takeshi Murouchi
      Abstract: Publication date: Available online 9 December 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Takeshi Murouchi


      PubDate: 2016-12-12T09:39:53Z
      DOI: 10.1016/j.aat.2016.10.003
       
  • Preincisional and postoperative epidural morphine, ropivacaine, ketamine,
           and naloxone treatment for postoperative pain management in upper
           abdominal surgery

    • Authors: Hou-Chuan Lai; Chung-Bao Hsieh; Chih-Shung Wong; Chun-Chang Yeh; Zhi-Fu Wu
      Abstract: Publication date: Available online 3 December 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Hou-Chuan Lai, Chung-Bao Hsieh, Chih-Shung Wong, Chun-Chang Yeh, Zhi-Fu Wu
      Objective(s) Previous studies have shown that preincisional epidural morphine, bupivacaine, and ketamine combined with epidural anesthesia (EA) and general anesthesia (GA) provided pre-emptive analgesia for upper abdominal surgery. Recent studies reported that ultralow-dose naloxone enhanced the antinociceptive effect of morphine in rats. This study investigated the benefits of preincisional and postoperative epidural morphine + ropivacaine + ketamine + naloxone (M + R + K + N) treatment for achieving postoperative pain relief in upper abdominal surgery. Methods Eighty American Society of Anesthesiology I–II patients scheduled for major upper abdominal surgery were allocated to four groups in a randomized, single-blinded study. All patients received combined GA and EA with a continuous epidural infusion of 2% lidocaine (6–8 mL/h) 30 minutes after pain regimen. After GA induction, in Group I, an epidural pain control regimen (total 10 mL) was administered using 1% lidocaine (8 mL) + morphine (2 mg) + ropivacaine (20 mg; M + R); in Group II, 1% lidocaine 8 (mL) + morphine (2 mg) + ropivacaine (20 mg) + ketamine (20 mg; M + R + K); in Group III, 1% lidocaine (8 mL) + morphine (2 mg) + ropivacaine (20 mg) + naloxone (2 μg; M + R + N); and in Group IV, 1% lidocaine (8 mL) + morphine (2 mg) + ropivacaine (20 mg) + ketamine (20 mg) + naloxone (2 μg; M + R + K + N), respectively. All patients received patient-controlled epidural analgesia (PCEA) with different pain regimens to control subsequent postoperative pain for 3 days following surgery. During the 3-day period following surgery, PCEA consumption (mL), numerical rating scale (NRS) score while cough/moving, and analgesic-related adverse effects were recorded. Results Total PCEA consumption for the 3-day observation period was 161.5±17.8 mL, 103.2±21.7 mL, 152.4±25.6 mL, and 74.1±16.9 mL for Groups I, II, III, and IV, respectively. (p < 0.05). The cough/moving NRS scores were significantly lower in Group IV patients than Groups I and III patients at 4 hours, 12 hours, and on Days 1 and 2 following surgery except for Group II (p < 0.05). Conclusion Preincisional and postoperative epidural M + R + K + N treatment provides an ideal postoperative pain management than preincisional and postoperative epidural M + R, M + R + K, and M + R + N treatments in upper abdominal surgery.

      PubDate: 2016-12-05T08:06:40Z
      DOI: 10.1016/j.aat.2016.10.004
       
  • Severe acute peripheral edema induced by noninvasive blood pressure cuff
           in an elderly patient with hypoalbuminemia under general anesthesia.

    • Authors: Chia-Chun Chuang; Jen-Yin Chen; Chien-Ching Lee
      Abstract: Publication date: Available online 1 December 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Chia-Chun Chuang, Jen-Yin Chen, Chien-Ching Lee


      PubDate: 2016-12-05T08:06:40Z
      DOI: 10.1016/j.aat.2016.11.001
       
  • Respiratory acidosis in obese gynecologic patients undergoing laparoscopic
           surgery independently of the type of ventilation.

    • Authors: Sergey S. Simakov; Xenia I. Roubliova; Alexey A. Ivanov; Anar K. Kaptaeva; Madina I. Mazitova; Ospan A. Mynbaev
      Abstract: Publication date: Available online 1 December 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Sergey S. Simakov, Xenia I. Roubliova, Alexey A. Ivanov, Anar K. Kaptaeva, Madina I. Mazitova, Ospan A. Mynbaev


      PubDate: 2016-12-05T08:06:40Z
      DOI: 10.1016/j.aat.2016.11.004
       
  • Reply to: Respiratory acidosis in obese gynecologic patients undergoing
           laparoscopic surgery independently of the type of ventilation

    • Authors: W.P. Zhang; S.M. Zhu
      Abstract: Publication date: Available online 1 December 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): W.P. Zhang, S.M. Zhu


      PubDate: 2016-12-05T08:06:40Z
      DOI: 10.1016/j.aat.2016.11.003
       
  • Perioperative medicine and Taiwan National Health Insurance Research
           Database

    • Authors: C.C. Chang; C.C. Liao; T.L. Chen
      Abstract: Publication date: Available online 18 November 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): C.C. Chang, C.C. Liao, T.L. Chen
      “Big data”, characterized by ‘volume’, ‘velocity’, ‘variety’, and ‘veracity’, being routinely collected in huge amounts of clinical and administrative healthcare-related data are becoming common and generating promising viewpoints for a better understanding of the complexity for medical situations. Taiwan National Health Insurance Research Database (NHIRD), one of large and comprehensive nationwide population reimbursement databases in the world, provides the strength of sample size avoiding selection and participation bias. Abundant with the demographics, clinical diagnoses, and capable of linking diverse laboratory and imaging information allowing for integrated analysis, NHIRD studies could inform us of the incidence, prevalence, managements, correlations and associations of clinical outcomes and diseases, under the universal coverage of healthcare used. Perioperative medicine has emerged as an important clinical research field over the past decade, moving the categorization of the specialty of “Anesthesiology and Perioperative Medicine”. Many studies concerning perioperative medicine based on retrospective cohort analyses have been published in the top-ranked journal, but studies utilizing Taiwan NHIRD were still not fully visualized. As the prominent growth curve of NHIRD studies, we have contributed the studies covering surgical adverse outcomes, trauma, stroke, diabetes, and healthcare inequality, etc., to this ever growing field for the past five years. It will definitely become a trend of research using Taiwan NHIRD and contributing to the progress of perioperative medicine with the recruitment of devotion from more research groups and become a famous doctrine.

      PubDate: 2016-11-20T20:27:36Z
      DOI: 10.1016/j.aat.2016.08.002
       
  • Alvimopan for post-operative ileus: What we should know?

    • Authors: Abhijit Nair
      Abstract: Publication date: Available online 5 November 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Abhijit Nair
      Alvimopan is an US-FDA approved, peripherally acting mu opioid receptor antagonist which when started pre-operatively has been shown to hasten intestinal motility and reduce the duration of post-operative ileus. However the logistics involved in procuring, storing and dispensing the drug and the cost of the drug for fifteen doses as approved by FDA prohibits the use of it on a regular basis.

      PubDate: 2016-11-07T15:40:52Z
      DOI: 10.1016/j.aat.2016.10.001
       
  • The risk of postoperative nausea and vomiting between surgical patients
           received propofol and sevoflurane anesthesia: A matched study

    • Authors: Hideki Matsuura; Satoki Inoue; Masahiko Kawaguchi
      Abstract: Publication date: Available online 4 November 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Hideki Matsuura, Satoki Inoue, Masahiko Kawaguchi
      Objectives The current consensus guidelines for managing postoperative nausea and vomiting (PONV) suggest that one of anesthetic risk factors is the use of volatile anesthetics. However, in clinical settings, it is rare to perceive propofol to be superior to volatile anesthetics for the prevention of PONV. To assess whether PONV is related to the type of anesthetic delivered, we compared the incidence and duration of PONV between propofol anesthesia and sevoflurane anesthesia. Methods We performed a retrospective review of an institutional registry containing 21606 general anesthesia cases conducted following ethics board approval. Anesthesia for all patients was managed with propofol or sevoflurane. To avoid channeling bias, a propensity score analysis was used to generate a set of matched cases (propofol anesthesia) and controls (sevoflurane anesthesia), yielding 2554 matched patient pairs. The incidence and sustained rate of symptoms were compared as the primary outcomes. Results In the unmatched population, a higher incidence of PONV occurred following propofol anesthesia compared to sevoflurane anesthesia (propofol vs. sevoflurane anesthesia: 18.9% vs. 15.3%, respectively, p < 0.0001). The sustained rate of PONV over the course after propofol anesthesia was also higher than that following sevoflurane anesthesia (p < 0.001). Conversely, less PONV occurred after propofol compared to sevoflurane after propensity matching (propofol vs. sevoflurane anesthesia: 20.4% vs. 23.3%, respectively, p = 0.01). However, the sustained rate of PONV over the course after propofol anesthesia did not differ from that following sevoflurane anesthesia (p = 0.09). Conclusions Propofol could decrease the incidence of PONV compared with sevoflurane, although the duration of PONV was not affected as found in previous reports.

      PubDate: 2016-11-07T15:40:52Z
      DOI: 10.1016/j.aat.2016.09.002
       
  • Chronic intrathecal infusion of T-type calcium channel blockers attenuates
           CaV3.2 upregulation in nerve-ligated rats

    • Authors: Sheng-Jie Shiue; Chi-Hsu Wang; Tao-Yeuan Wang; Yi-Chun Chen; Jen-Kun Cheng
      Abstract: Publication date: Available online 17 October 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Sheng-Jie Shiue, Chi-Hsu Wang, Tao-Yeuan Wang, Yi-Chun Chen, Jen-Kun Cheng
      Objective T-type channel (TCC) CaV3.2 plays a pivotal role in pain transmission. In this study, we examined the effects of intrathecal TCC blockers on CaV3.2 expression in a L5/6 spinal nerve ligation (SNL) pain model. The neurotoxicity of TCC blockers were also evaluated. Methods Male Sprague-Dawley rats (200–250 g) were used for right L5/6 SNL to induce neuropathic pain. Intrathecal infusion of saline or TCC blockers [mibefradil (0.7 μg/h) or ethosuximide (60 μg/h)] was started after surgery for 7 days. Fluorescent immunohistochemistry and Western blotting were used to determine the expression pattern and protein level of CaV3.2. Hematoxylin–eosin and toluidine blue staining were used to evaluate the neurotoxicity of tested agents. Results Seven days after SNL, CaV3.2 protein levels were upregulated in ipsi-lateral L5/6 spinal cord and dorsal root ganglia (DRG) in immunofluorescence and Western blotting studies. Compared with the saline-treated group, rats receiving mibefradil or ethosuximide showed significant lower CaV3.2 expression in the spinal cord and DRG. No obvious histopathologic change in hematoxylin–eosin and toluidine blue staining were observed in all tested groups. Conclusion In this study, we demonstrate that SNL-induced CaV3.2 upregulation in the spinal cord and DRG was attenuated by intrathecal infusion of mibefradil or ethosuximide. No obvious neurotoxicity effects were observed in all the tested groups. Our data suggest that continuous intrathecal infusion of TCC blockers may be considered as a promising alternative for the treatment of nerve injury-induced pain.

      PubDate: 2016-10-31T12:40:33Z
      DOI: 10.1016/j.aat.2016.09.001
       
  • Adductor canal block and lateral approach of sciatic nerve block at the
           midthigh level

    • Authors: Yasuhiro Morimoto; Tatsunori Haruoka
      Abstract: Publication date: Available online 1 October 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Yasuhiro Morimoto, Tatsunori Haruoka


      PubDate: 2016-10-03T17:39:46Z
      DOI: 10.1016/j.aat.2016.08.001
       
  • Intraoperative multiple intercostal nerve blocks exert anesthetic-sparing
           effect: A retrospective study on the effect-site concentration of propofol
           infusion in nonintubated thoracoscopic surgery

    • Authors: Man-Ling Wang; Ming-Hui Hung; Kuang-Cheng Chan; Jin-Shing Chen; Ya-Jung Cheng
      Abstract: Publication date: Available online 23 August 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Man-Ling Wang, Ming-Hui Hung, Kuang-Cheng Chan, Jin-Shing Chen, Ya-Jung Cheng
      Objective(s) Less general anesthetic is required in patients with regional blocks than in those without, as assessed through commonly used anesthesia monitoring parameters such as blood pressure, heart rate, and bispectral index (BIS). Although intraoperative regional anesthesia has become more widely adopted, few studies have confirmed or monitored its anesthetic-sparing effects. Using recent reports of nonintubated video-assisted thoracoscopic surgery (VATS) by BIS-targeted propofol infusion and intraoperative multilevel thoracoscopic intercostal nerve blocks (TINBs), this retrospective study investigated whether the anesthetic-sparing effect can be realized by reducing the effect-site concentration (Ce) to the targeted BIS level or by reducing the blood pressure at the onset of regional blocks. Methods A retrospective study of a prospectively collected case series of non-intubated VATS. Results Data on 56 adult patients who underwent nonintubated VATS were collected and analyzed. The mean operative time was 121 ± 32 minutes. BIS levels before and after one-lung ventilation/TINBs and surgery were 48% ± 11% and 47% ± 12%, respectively. The Ce of propofol infusion decreased significantly from 3.4 ± 0.8 μg/mL to 3.0 ± 0.7 μg/mL (p < 0.01) after surgery with TINBs. Blood pressure did not change significantly, whereas the heart rate increased moderately but significantly (77 ± 14 beats/minute to 82 ± 15 beats/minute, p < 0.01). Conclusion With comparable BIS and blood pressure in the subsequent surgical procedure, the adequacy of anesthesia and the anesthetic component provided by intraoperative TINBs and vagal nerve could be monitored adequately. The anesthetic-sparing effect of intraoperative nerve blocks can be realized when the Ce of propofol infusion was reduced to the target BIS level.

      PubDate: 2016-09-16T04:06:59Z
      DOI: 10.1016/j.aat.2016.07.001
       
  • Trend of academic publication activity in anesthesiology: A 2-decade
           bibliographic perspective

    • Authors: Sy-Yuan Chen; Ling-Fang Wei; Chiu-Ming Ho
      Abstract: Publication date: Available online 16 August 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Sy-Yuan Chen, Ling-Fang Wei, Chiu-Ming Ho
      Objectives The publication of anesthesiology papers presents the importance of understanding the corresponding research activity. This research used the bibliographic method to investigate the publication trend in anesthesiology using Science Citation Index Expanded over the period 1995–2014. Methods The journals listed in the subject category of anesthesiology in the 2014 Journal Citation Reports were selected, and bibliographic information was collected from Science Citation Index Expanded, with 128,003 papers published from 1995 to 2014. Only the document type “article” was analyzed. The productivity and impact of various journals, countries, and institutions are discussed. Results A total of 64,199 articles published from 1995 to 2014, with 1,084,491 cited times, were examined. The total number of articles published by journals showed a slight increase in the 2nd decade. More than 45% of these articles were published by the top five journals, which have maintained their ranking over 2 decades. Most publications originated from North America and European countries, of which the United States had the highest number of publications and citations. Most of the institutions are academic universities and hospitals. More than half of the top 25 institutions (in rankings) are located in the United States, and Harvard University accounted the highest number of articles and citations among all institutions. Conclusion The results reported here may aid clinicians and researchers to better understand the worldwide contribution of anesthesiology research activities over 2 decades.

      PubDate: 2016-09-16T04:06:59Z
      DOI: 10.1016/j.aat.2016.06.005
       
  • Observation of ultrasound-guided thoracic paravertebral block using
           thoracoscopy

    • Authors: Tasuku Fujii; Yasuyuki Shibata; Kimitoshi Nishiwaki
      Abstract: Publication date: Available online 24 June 2016
      Source:Acta Anaesthesiologica Taiwanica
      Author(s): Tasuku Fujii, Yasuyuki Shibata, Kimitoshi Nishiwaki


      PubDate: 2016-09-16T04:06:59Z
      DOI: 10.1016/j.aat.2016.05.004
       
 
 
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