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Publisher: Elsevier   (Total: 3043 journals)

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Showing 1 - 200 of 3043 Journals sorted alphabetically
AASRI Procedia     Open Access   (Followers: 15)
Academic Pediatrics     Hybrid Journal   (Followers: 22, SJR: 1.402, h-index: 51)
Academic Radiology     Hybrid Journal   (Followers: 21, SJR: 1.008, h-index: 75)
Accident Analysis & Prevention     Partially Free   (Followers: 84, SJR: 1.109, h-index: 94)
Accounting Forum     Hybrid Journal   (Followers: 25, SJR: 0.612, h-index: 27)
Accounting, Organizations and Society     Hybrid Journal   (Followers: 30, SJR: 2.515, h-index: 90)
Achievements in the Life Sciences     Open Access   (Followers: 4)
Acta Anaesthesiologica Taiwanica     Open Access   (Followers: 5, SJR: 0.338, h-index: 19)
Acta Astronautica     Hybrid Journal   (Followers: 352, SJR: 0.726, h-index: 43)
Acta Automatica Sinica     Full-text available via subscription   (Followers: 3)
Acta Biomaterialia     Hybrid Journal   (Followers: 25, SJR: 2.02, h-index: 104)
Acta Colombiana de Cuidado Intensivo     Full-text available via subscription   (Followers: 1)
Acta de Investigación Psicológica     Open Access   (Followers: 2)
Acta Ecologica Sinica     Open Access   (Followers: 8, SJR: 0.172, h-index: 29)
Acta Haematologica Polonica     Free   (SJR: 0.123, h-index: 8)
Acta Histochemica     Hybrid Journal   (Followers: 3, SJR: 0.604, h-index: 38)
Acta Materialia     Hybrid Journal   (Followers: 235, SJR: 3.683, h-index: 202)
Acta Mathematica Scientia     Full-text available via subscription   (Followers: 5, SJR: 0.615, h-index: 21)
Acta Mechanica Solida Sinica     Full-text available via subscription   (Followers: 9, SJR: 0.442, h-index: 21)
Acta Oecologica     Hybrid Journal   (Followers: 10, SJR: 0.915, h-index: 53)
Acta Otorrinolaringologica (English Edition)     Full-text available via subscription   (Followers: 1)
Acta Otorrinolaringológica Española     Full-text available via subscription   (Followers: 3, SJR: 0.311, h-index: 16)
Acta Pharmaceutica Sinica B     Open Access   (Followers: 2)
Acta Poética     Open Access   (Followers: 4)
Acta Psychologica     Hybrid Journal   (Followers: 23, SJR: 1.365, h-index: 73)
Acta Sociológica     Open Access  
Acta Tropica     Hybrid Journal   (Followers: 6, SJR: 1.059, h-index: 77)
Acta Urológica Portuguesa     Open Access  
Actas Dermo-Sifiliograficas     Full-text available via subscription   (Followers: 4)
Actas Dermo-Sifiliográficas (English Edition)     Full-text available via subscription   (Followers: 3)
Actas Urológicas Españolas     Full-text available via subscription   (Followers: 4, SJR: 0.383, h-index: 19)
Actas Urológicas Españolas (English Edition)     Full-text available via subscription   (Followers: 2)
Actualites Pharmaceutiques     Full-text available via subscription   (Followers: 5, SJR: 0.141, h-index: 3)
Actualites Pharmaceutiques Hospitalieres     Full-text available via subscription   (Followers: 4, SJR: 0.112, h-index: 2)
Acupuncture and Related Therapies     Hybrid Journal   (Followers: 4)
Acute Pain     Full-text available via subscription   (Followers: 13)
Ad Hoc Networks     Hybrid Journal   (Followers: 11, SJR: 0.967, h-index: 57)
Addictive Behaviors     Hybrid Journal   (Followers: 15, SJR: 1.514, h-index: 92)
Addictive Behaviors Reports     Open Access   (Followers: 5)
Additive Manufacturing     Hybrid Journal   (Followers: 7, SJR: 1.039, h-index: 5)
Additives for Polymers     Full-text available via subscription   (Followers: 21)
Advanced Drug Delivery Reviews     Hybrid Journal   (Followers: 135, SJR: 5.2, h-index: 222)
Advanced Engineering Informatics     Hybrid Journal   (Followers: 11, SJR: 1.265, h-index: 53)
Advanced Powder Technology     Hybrid Journal   (Followers: 17, SJR: 0.739, h-index: 33)
Advances in Accounting     Hybrid Journal   (Followers: 9, SJR: 0.299, h-index: 15)
Advances in Agronomy     Full-text available via subscription   (Followers: 15, SJR: 2.071, h-index: 82)
Advances in Anesthesia     Full-text available via subscription   (Followers: 25, SJR: 0.169, h-index: 4)
Advances in Antiviral Drug Design     Full-text available via subscription   (Followers: 3)
Advances in Applied Mathematics     Full-text available via subscription   (Followers: 6, SJR: 1.054, h-index: 35)
Advances in Applied Mechanics     Full-text available via subscription   (Followers: 11, SJR: 0.801, h-index: 26)
Advances in Applied Microbiology     Full-text available via subscription   (Followers: 22, SJR: 1.286, h-index: 49)
Advances In Atomic, Molecular, and Optical Physics     Full-text available via subscription   (Followers: 16, SJR: 3.31, h-index: 42)
Advances in Biological Regulation     Hybrid Journal   (Followers: 4, SJR: 2.277, h-index: 43)
Advances in Botanical Research     Full-text available via subscription   (Followers: 3, SJR: 0.619, h-index: 48)
Advances in Cancer Research     Full-text available via subscription   (Followers: 25, SJR: 2.215, h-index: 78)
Advances in Carbohydrate Chemistry and Biochemistry     Full-text available via subscription   (Followers: 9, SJR: 0.9, h-index: 30)
Advances in Catalysis     Full-text available via subscription   (Followers: 5, SJR: 2.139, h-index: 42)
Advances in Cellular and Molecular Biology of Membranes and Organelles     Full-text available via subscription   (Followers: 12)
Advances in Chemical Engineering     Full-text available via subscription   (Followers: 26, SJR: 0.183, h-index: 23)
Advances in Child Development and Behavior     Full-text available via subscription   (Followers: 10, SJR: 0.665, h-index: 29)
Advances in Chronic Kidney Disease     Full-text available via subscription   (Followers: 9, SJR: 1.268, h-index: 45)
Advances in Clinical Chemistry     Full-text available via subscription   (Followers: 29, SJR: 0.938, h-index: 33)
Advances in Colloid and Interface Science     Full-text available via subscription   (Followers: 18, SJR: 2.314, h-index: 130)
Advances in Computers     Full-text available via subscription   (Followers: 16, SJR: 0.223, h-index: 22)
Advances in Dermatology     Full-text available via subscription   (Followers: 12)
Advances in Developmental Biology     Full-text available via subscription   (Followers: 11)
Advances in Digestive Medicine     Open Access   (Followers: 6)
Advances in DNA Sequence-Specific Agents     Full-text available via subscription   (Followers: 5)
Advances in Drug Research     Full-text available via subscription   (Followers: 22)
Advances in Ecological Research     Full-text available via subscription   (Followers: 41, SJR: 3.25, h-index: 43)
Advances in Engineering Software     Hybrid Journal   (Followers: 25, SJR: 0.486, h-index: 10)
Advances in Experimental Biology     Full-text available via subscription   (Followers: 7)
Advances in Experimental Social Psychology     Full-text available via subscription   (Followers: 41, SJR: 5.465, h-index: 64)
Advances in Exploration Geophysics     Full-text available via subscription   (Followers: 3)
Advances in Food and Nutrition Research     Full-text available via subscription   (Followers: 50, SJR: 0.674, h-index: 38)
Advances in Fuel Cells     Full-text available via subscription   (Followers: 16)
Advances in Genetics     Full-text available via subscription   (Followers: 15, SJR: 2.558, h-index: 54)
Advances in Genome Biology     Full-text available via subscription   (Followers: 11)
Advances in Geophysics     Full-text available via subscription   (Followers: 6, SJR: 2.325, h-index: 20)
Advances in Heat Transfer     Full-text available via subscription   (Followers: 22, SJR: 0.906, h-index: 24)
Advances in Heterocyclic Chemistry     Full-text available via subscription   (Followers: 9, SJR: 0.497, h-index: 31)
Advances in Imaging and Electron Physics     Full-text available via subscription   (Followers: 2, SJR: 0.396, h-index: 27)
Advances in Immunology     Full-text available via subscription   (Followers: 35, SJR: 4.152, h-index: 85)
Advances in Inorganic Chemistry     Full-text available via subscription   (Followers: 9, SJR: 1.132, h-index: 42)
Advances in Insect Physiology     Full-text available via subscription   (Followers: 3, SJR: 1.274, h-index: 27)
Advances in Integrative Medicine     Hybrid Journal   (Followers: 6)
Advances in Life Course Research     Hybrid Journal   (Followers: 8, SJR: 0.764, h-index: 15)
Advances in Lipobiology     Full-text available via subscription   (Followers: 2)
Advances in Magnetic and Optical Resonance     Full-text available via subscription   (Followers: 9)
Advances in Marine Biology     Full-text available via subscription   (Followers: 16, SJR: 1.645, h-index: 45)
Advances in Mathematics     Full-text available via subscription   (Followers: 10, SJR: 3.261, h-index: 65)
Advances in Medical Sciences     Hybrid Journal   (Followers: 6, SJR: 0.489, h-index: 25)
Advances in Medicinal Chemistry     Full-text available via subscription   (Followers: 5)
Advances in Microbial Physiology     Full-text available via subscription   (Followers: 4, SJR: 1.44, h-index: 51)
Advances in Molecular and Cell Biology     Full-text available via subscription   (Followers: 22)
Advances in Molecular and Cellular Endocrinology     Full-text available via subscription   (Followers: 10)
Advances in Molecular Toxicology     Full-text available via subscription   (Followers: 7, SJR: 0.324, h-index: 8)
Advances in Nanoporous Materials     Full-text available via subscription   (Followers: 4)
Advances in Oncobiology     Full-text available via subscription   (Followers: 3)
Advances in Organometallic Chemistry     Full-text available via subscription   (Followers: 15, SJR: 2.885, h-index: 45)
Advances in Parallel Computing     Full-text available via subscription   (Followers: 7, SJR: 0.148, h-index: 11)
Advances in Parasitology     Full-text available via subscription   (Followers: 7, SJR: 2.37, h-index: 73)
Advances in Pediatrics     Full-text available via subscription   (Followers: 24, SJR: 0.4, h-index: 28)
Advances in Pharmaceutical Sciences     Full-text available via subscription   (Followers: 13)
Advances in Pharmacology     Full-text available via subscription   (Followers: 15, SJR: 1.718, h-index: 58)
Advances in Physical Organic Chemistry     Full-text available via subscription   (Followers: 8, SJR: 0.384, h-index: 26)
Advances in Phytomedicine     Full-text available via subscription  
Advances in Planar Lipid Bilayers and Liposomes     Full-text available via subscription   (Followers: 3, SJR: 0.248, h-index: 11)
Advances in Plant Biochemistry and Molecular Biology     Full-text available via subscription   (Followers: 8)
Advances in Plant Pathology     Full-text available via subscription   (Followers: 5)
Advances in Porous Media     Full-text available via subscription   (Followers: 4)
Advances in Protein Chemistry     Full-text available via subscription   (Followers: 17)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 20, SJR: 1.5, h-index: 62)
Advances in Psychology     Full-text available via subscription   (Followers: 61)
Advances in Quantum Chemistry     Full-text available via subscription   (Followers: 5, SJR: 0.478, h-index: 32)
Advances in Radiation Oncology     Open Access  
Advances in Small Animal Medicine and Surgery     Hybrid Journal   (Followers: 3, SJR: 0.1, h-index: 2)
Advances in Space Research     Full-text available via subscription   (Followers: 353, SJR: 0.606, h-index: 65)
Advances in Structural Biology     Full-text available via subscription   (Followers: 8)
Advances in Surgery     Full-text available via subscription   (Followers: 7, SJR: 0.823, h-index: 27)
Advances in the Study of Behavior     Full-text available via subscription   (Followers: 30, SJR: 1.321, h-index: 56)
Advances in Veterinary Medicine     Full-text available via subscription   (Followers: 17)
Advances in Veterinary Science and Comparative Medicine     Full-text available via subscription   (Followers: 13)
Advances in Virus Research     Full-text available via subscription   (Followers: 5, SJR: 1.878, h-index: 68)
Advances in Water Resources     Hybrid Journal   (Followers: 43, SJR: 2.408, h-index: 94)
Aeolian Research     Hybrid Journal   (Followers: 5, SJR: 0.973, h-index: 22)
Aerospace Science and Technology     Hybrid Journal   (Followers: 325, SJR: 0.816, h-index: 49)
AEU - Intl. J. of Electronics and Communications     Hybrid Journal   (Followers: 8, SJR: 0.318, h-index: 36)
African J. of Emergency Medicine     Open Access   (Followers: 5, SJR: 0.344, h-index: 6)
Ageing Research Reviews     Hybrid Journal   (Followers: 8, SJR: 3.289, h-index: 78)
Aggression and Violent Behavior     Hybrid Journal   (Followers: 406, SJR: 1.385, h-index: 72)
Agri Gene     Hybrid Journal  
Agricultural and Forest Meteorology     Hybrid Journal   (Followers: 16, SJR: 2.18, h-index: 116)
Agricultural Systems     Hybrid Journal   (Followers: 30, SJR: 1.275, h-index: 74)
Agricultural Water Management     Hybrid Journal   (Followers: 39, SJR: 1.546, h-index: 79)
Agriculture and Agricultural Science Procedia     Open Access  
Agriculture and Natural Resources     Open Access   (Followers: 1)
Agriculture, Ecosystems & Environment     Hybrid Journal   (Followers: 54, SJR: 1.879, h-index: 120)
Ain Shams Engineering J.     Open Access   (Followers: 5, SJR: 0.434, h-index: 14)
Air Medical J.     Hybrid Journal   (Followers: 5, SJR: 0.234, h-index: 18)
AKCE Intl. J. of Graphs and Combinatorics     Open Access   (SJR: 0.285, h-index: 3)
Alcohol     Hybrid Journal   (Followers: 11, SJR: 0.922, h-index: 66)
Alcoholism and Drug Addiction     Open Access   (Followers: 8)
Alergologia Polska : Polish J. of Allergology     Full-text available via subscription   (Followers: 1)
Alexandria Engineering J.     Open Access   (Followers: 1, SJR: 0.436, h-index: 12)
Alexandria J. of Medicine     Open Access  
Algal Research     Partially Free   (Followers: 8, SJR: 2.05, h-index: 20)
Alkaloids: Chemical and Biological Perspectives     Full-text available via subscription   (Followers: 3)
Allergologia et Immunopathologia     Full-text available via subscription   (Followers: 1, SJR: 0.46, h-index: 29)
Allergology Intl.     Open Access   (Followers: 4, SJR: 0.776, h-index: 35)
Alpha Omegan     Full-text available via subscription   (SJR: 0.121, h-index: 9)
ALTER - European J. of Disability Research / Revue Européenne de Recherche sur le Handicap     Full-text available via subscription   (Followers: 8, SJR: 0.158, h-index: 9)
Alzheimer's & Dementia     Hybrid Journal   (Followers: 48, SJR: 4.289, h-index: 64)
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring     Open Access   (Followers: 6)
Alzheimer's & Dementia: Translational Research & Clinical Interventions     Open Access   (Followers: 5)
American Heart J.     Hybrid Journal   (Followers: 49, SJR: 3.157, h-index: 153)
American J. of Cardiology     Hybrid Journal   (Followers: 47, SJR: 2.063, h-index: 186)
American J. of Emergency Medicine     Hybrid Journal   (Followers: 39, SJR: 0.574, h-index: 65)
American J. of Geriatric Pharmacotherapy     Full-text available via subscription   (Followers: 8, SJR: 1.091, h-index: 45)
American J. of Geriatric Psychiatry     Hybrid Journal   (Followers: 15, SJR: 1.653, h-index: 93)
American J. of Human Genetics     Hybrid Journal   (Followers: 31, SJR: 8.769, h-index: 256)
American J. of Infection Control     Hybrid Journal   (Followers: 25, SJR: 1.259, h-index: 81)
American J. of Kidney Diseases     Hybrid Journal   (Followers: 32, SJR: 2.313, h-index: 172)
American J. of Medicine     Hybrid Journal   (Followers: 45, SJR: 2.023, h-index: 189)
American J. of Medicine Supplements     Full-text available via subscription   (Followers: 3)
American J. of Obstetrics and Gynecology     Hybrid Journal   (Followers: 233, SJR: 2.255, h-index: 171)
American J. of Ophthalmology     Hybrid Journal   (Followers: 58, SJR: 2.803, h-index: 148)
American J. of Ophthalmology Case Reports     Open Access   (Followers: 5)
American J. of Orthodontics and Dentofacial Orthopedics     Full-text available via subscription   (Followers: 6, SJR: 1.249, h-index: 88)
American J. of Otolaryngology     Hybrid Journal   (Followers: 25, SJR: 0.59, h-index: 45)
American J. of Pathology     Hybrid Journal   (Followers: 26, SJR: 2.653, h-index: 228)
American J. of Preventive Medicine     Hybrid Journal   (Followers: 22, SJR: 2.764, h-index: 154)
American J. of Surgery     Hybrid Journal   (Followers: 34, SJR: 1.286, h-index: 125)
American J. of the Medical Sciences     Hybrid Journal   (Followers: 12, SJR: 0.653, h-index: 70)
Ampersand : An Intl. J. of General and Applied Linguistics     Open Access   (Followers: 5)
Anaerobe     Hybrid Journal   (Followers: 4, SJR: 1.066, h-index: 51)
Anaesthesia & Intensive Care Medicine     Full-text available via subscription   (Followers: 57, SJR: 0.124, h-index: 9)
Anaesthesia Critical Care & Pain Medicine     Full-text available via subscription   (Followers: 11)
Anales de Cirugia Vascular     Full-text available via subscription  
Anales de Pediatría     Full-text available via subscription   (Followers: 2, SJR: 0.209, h-index: 27)
Anales de Pediatría (English Edition)     Full-text available via subscription  
Anales de Pediatría Continuada     Full-text available via subscription   (SJR: 0.104, h-index: 3)
Analytic Methods in Accident Research     Hybrid Journal   (Followers: 4, SJR: 2.577, h-index: 7)
Analytica Chimica Acta     Hybrid Journal   (Followers: 37, SJR: 1.548, h-index: 152)
Analytical Biochemistry     Hybrid Journal   (Followers: 167, SJR: 0.725, h-index: 154)
Analytical Chemistry Research     Open Access   (Followers: 8, SJR: 0.18, h-index: 2)
Analytical Spectroscopy Library     Full-text available via subscription   (Followers: 11)
Anesthésie & Réanimation     Full-text available via subscription   (Followers: 1)
Anesthesiology Clinics     Full-text available via subscription   (Followers: 22, SJR: 0.421, h-index: 40)
Angiología     Full-text available via subscription   (SJR: 0.124, h-index: 9)
Angiologia e Cirurgia Vascular     Open Access  
Animal Behaviour     Hybrid Journal   (Followers: 161, SJR: 1.907, h-index: 126)
Animal Feed Science and Technology     Hybrid Journal   (Followers: 5, SJR: 1.151, h-index: 83)
Animal Reproduction Science     Hybrid Journal   (Followers: 5, SJR: 0.711, h-index: 78)
Annales d'Endocrinologie     Full-text available via subscription   (Followers: 1, SJR: 0.394, h-index: 30)
Annales d'Urologie     Full-text available via subscription  
Annales de Cardiologie et d'Angéiologie     Full-text available via subscription   (SJR: 0.177, h-index: 13)
Annales de Chirurgie de la Main et du Membre Supérieur     Full-text available via subscription  
Annales de Chirurgie Plastique Esthétique     Full-text available via subscription   (Followers: 2, SJR: 0.354, h-index: 22)
Annales de Chirurgie Vasculaire     Full-text available via subscription   (Followers: 1)

        1 2 3 4 5 6 7 8 | Last   [Sort by number of followers]   [Restore default list]

Journal Cover Advances in Structural Biology
  [8 followers]  Follow
    
   Full-text available via subscription Subscription journal
   ISSN (Print) 1064-6000
   Published by Elsevier Homepage  [3043 journals]
  • List of contributors
    • Abstract: 2000
      Publication year: 2000
      Source:Advances in Structural Biology, Volume 6



      PubDate: 2012-12-17T18:14:10Z
       
  • Fluorescent in situ hybridization (fish) as an adjunct to conventional
           cytogenetics Analysis of metaphase and interphase cells
    • Abstract: 2000
      Publication year: 2000
      Source:Advances in Structural Biology, Volume 6



      PubDate: 2012-12-17T18:14:10Z
       
  • The contribution of defects in insulin signaling in skeletal muscle to
           insulin resistance and type 2 diabetes Cellular and molecular aspects
    • Abstract: 2000
      Publication year: 2000
      Source:Advances in Structural Biology, Volume 6



      PubDate: 2012-12-17T18:14:10Z
       
  • Cytopathic hypoxia in septic shock
    • Abstract: 2000
      Publication year: 2000
      Source:Advances in Structural Biology, Volume 6



      PubDate: 2012-12-17T18:14:10Z
       
  • Bone healing and the differentiation of osteoprogenitor cells in mammals
    • Abstract: 2000
      Publication year: 2000
      Source:Advances in Structural Biology, Volume 6



      PubDate: 2012-12-17T18:14:10Z
       
  • Polymine-traveled pathways Significance in health and disease
    • Abstract: 2000
      Publication year: 2000
      Source:Advances in Structural Biology, Volume 6



      PubDate: 2012-12-17T18:14:10Z
       
  • Reactive astrocytes, their roles in CNS injury, and repair mechanisms
    • Abstract: 2000
      Publication year: 2000
      Source:Advances in Structural Biology, Volume 6



      PubDate: 2012-12-17T18:14:10Z
       
  • Plasticity and rigidity in the nervous system Lessons from the spinal cord
    • Abstract: 2000
      Publication year: 2000
      Source:Advances in Structural Biology, Volume 6



      PubDate: 2012-12-17T18:14:10Z
       
  • Ceruloplasmin Structure and function of an essential ferroxidase
    • Abstract: 2000
      Publication year: 2000
      Source:Advances in Structural Biology, Volume 6



      PubDate: 2012-12-17T18:14:10Z
       
  • Expression of a novel nuclear protein is correlated with brain development
    • Abstract: 2000
      Publication year: 2000
      Source:Advances in Structural Biology, Volume 6



      PubDate: 2012-12-17T18:14:10Z
       
  • Structure-Function relationships of the nuclear envelope
    • Abstract: 2000
      Publication year: 2000
      Source:Advances in Structural Biology, Volume 6



      PubDate: 2012-12-17T18:14:10Z
       
  • Membrane pores
    • Abstract: 2000
      Publication year: 2000
      Source:Advances in Structural Biology, Volume 6



      PubDate: 2012-12-17T18:14:10Z
       
  • List of contributors
    • Abstract: 1999
      Publication year: 1999
      Source:Advances in Structural Biology, Volume 5



      PubDate: 2012-12-17T18:14:10Z
       
  • Regulation of bidirectional pigment granule movement in melanophores
    • Abstract: 1999
      Publication year: 1999
      Source:Advances in Structural Biology, Volume 5



      PubDate: 2012-12-17T18:14:10Z
       
  • Ciliated cell electrodynamics: From cilia and flagella to ciliated sensory
           systems
    • Abstract: 1999
      Publication year: 1999
      Source:Advances in Structural Biology, Volume 5



      PubDate: 2012-12-17T18:14:10Z
       
  • Microtubule self-organization as an example of a biological turing
           structure
    • Abstract: 1999
      Publication year: 1999
      Source:Advances in Structural Biology, Volume 5



      PubDate: 2012-12-17T18:14:10Z
       
  • Molecular automata modeling in structural biology
    • Abstract: 1999
      Publication year: 1999
      Source:Advances in Structural Biology, Volume 5



      PubDate: 2012-12-17T18:14:10Z
       
  • On the interaction of magnetic fields with coherent (bio)chemical
           reactions
    • Abstract: 1999
      Publication year: 1999
      Source:Advances in Structural Biology, Volume 5



      PubDate: 2012-12-17T18:14:10Z
       
  • Reflections of biological signaling: Electronic conduction may be an
           important intracellular pathway
    • Abstract: 1999
      Publication year: 1999
      Source:Advances in Structural Biology, Volume 5



      PubDate: 2012-12-17T18:14:10Z
       
  • Ferroelectrics and their possible involvement in biology
    • Abstract: 1999
      Publication year: 1999
      Source:Advances in Structural Biology, Volume 5



      PubDate: 2012-12-17T18:14:10Z
       
  • Viscoelasticity of biopolymer networks and statistical mechanics of
           semiflexible polymers
    • Abstract: 1999
      Publication year: 1999
      Source:Advances in Structural Biology, Volume 5



      PubDate: 2012-12-17T18:14:10Z
       
  • Stochastic data analysis for the assembly and disassembly of microtubules
           in vitro
    • Abstract: 1999
      Publication year: 1999
      Source:Advances in Structural Biology, Volume 5



      PubDate: 2012-12-17T18:14:10Z
       
  • Structural and functional properties of tubulin isotypes
    • Abstract: 1999
      Publication year: 1999
      Source:Advances in Structural Biology, Volume 5



      PubDate: 2012-12-17T18:14:10Z
       
  • Single myosin molecule mechanics
    • Abstract: 1999
      Publication year: 1999
      Source:Advances in Structural Biology, Volume 5



      PubDate: 2012-12-17T18:14:10Z
       
  • Motor proteins have highly correlated brownian engines
    • Abstract: 1999
      Publication year: 1999
      Source:Advances in Structural Biology, Volume 5



      PubDate: 2012-12-17T18:14:10Z
       
  • Quantum mechanics in cell microtubules Wild imagination or realistic
           possibility
    • Abstract: 1999
      Publication year: 1999
      Source:Advances in Structural Biology, Volume 5



      PubDate: 2012-12-17T18:14:10Z
       
  • List of contributors
    • Abstract: 1996
      Publication year: 1996
      Source:Advances in Structural Biology, Volume 4



      PubDate: 2012-12-17T18:14:10Z
       
  • Conservation of genome and gene structure from fishes to mammals
    • Abstract: 1996
      Publication year: 1996
      Source:Advances in Structural Biology, Volume 4



      PubDate: 2012-12-17T18:14:10Z
       
  • The molecular composition of the tight junction
    • Abstract: 1996
      Publication year: 1996
      Source:Advances in Structural Biology, Volume 4



      PubDate: 2012-12-17T18:14:10Z
       
  • The gap junction
    • Abstract: 1996
      Publication year: 1996
      Source:Advances in Structural Biology, Volume 4

      Gap junctions are ubiquitous in vertebrates and invertebrates with certain exceptions, such as mature skeletal muscle and spermatocytes. A number of different connexins have been identified todate which constitute a multigene family of related but distinct members, and connexins are expressed in temporally and spatially regulated manner. A great deal of effort has been expended to understand the structural components of gap junctions, their arrangement in channel formation, tissue distribution, and their regulation. These efforts have produced detailed information on the structure of the gap junction channels, electrical conduction properties, and different levels of regulatory controls ranging from the synthesis of the transcripts for connexin to the opening and closing of the channels. However, two distinct areas of research have shown meager results; these are (a) assembly ofconnexins into the hexameric connexon and ultimately in gap junction formation, and (b) specific role(s) of gap junctions in the cellular physiology of non-excitable cells. Progress in delineating the processes of assembly and intracellular transport has been dependent on the availability of molecular probes such as specific antibodies which have now become available (Hertzberg, 1985; Kumar and Gilula, 1992).The role of gap junctions in electrotonic coupling of neurons and synchronization of excitable cells such as cardiac and smooth muscle cells has been well established (reviewed by Bennett, 1973; Sheridan and Atkinson, 1985). However, their role in the non-excitable cells has long been a subject of speculations based on circumstantial evidence except for a finding that mutations in a Schwann cell connexin gene may lead to Charcot-Marie Tooth disease of the peripheral nervous system (Bergoffen et al., 1993a,b) which leads to nerve degeneration. In another recent report, Reaume et al. (1995) targeted a mutation in a connexin gene (Cx43) of mouse and observed cardiac malformation during embryonic development. Gap junctions also have been implicated in loss of growth control and tumor suppression (reviewed by Loewenstein, 1979; Bertram, 1990; Loewenstein and Rose, 1992). Correlative evidence for this hypothesis emanates from studies that showed that (a) many tumor cells are defective in gap junctional communication, (b) viral transformation of cultured cells results in the loss of gap junctions, and (c) tumor-promoter agents such as TPA inhibit gap junctional communication. It has been hypothesized (Loewenstein, 1979; Loewenstein and Rose, 1992) that growth regulatory molecules can diffuse through the gap junction channels and exert their growth regulatory effects on neighboring cells. Regulatory molecules such as calcium ions, inositol phosphate, or cyclic nucleotides, in theory, may pass from one cell to another through these channels, but the identity of these regulatory molecules has not been established. However, the idea of a direct role of gap junctional communication as a primary growth regulatory mechanism is controversial because of the following reasons; (a) many tumor cells and malignant cell lines do form gap junctions and exhibit intercellular communication (Bennett et al., 1991), (b) during embryonic development gap junctions are formed as early as the eight-cell stage, and yet cell proliferation during embryogenesis is more rapid than in many tumors, (c) "knock-out" mice lacking a connexin43 gene (a gap junction gene which is expressed as early as the eight-cell stage of embryogenesis) developed to birth and showed only cardiac malformations (Reaume et al., 1995). By experimentally causing the overexpression of Cx43 in the connexin-deficient C6 rat glioma cell line, it has been shown that the growth of cells decreased in cultures (Zhu et al., 1991). Thus, a direct relationship between gap junctional intercellular communication and the growth of C6 cells was proposed. The ubiquitous presence of gap junctions and their relatively conserved molecular structures indicate their importance in vertebrate physiology, yet the tissue and stage-specific expression of different connexins argues against them having a common role in different tissues. Moreover, the function of gap junctional communication may be supplementary to other cellular regulatory mechanisms because the loss of gap junctional potential does not affect cellular viability. That gap junctions are not indispensable has been shown by the development of"knock-out" mice to full-term (Reaume et al., 1995); the mutation in Cx43 which is expressed even at eight-cell stage in the mouse embryo did not affect embryo development other than to produce cardiac malformations. It is known that different connexins impart distinct electrophysiological properties to the gap junctional channels in which they occur (Bennett et al., 1991; Bennett and Verselis, 1992). Therefore, it is possible that a multiplicity of connexins provide supplementary functions in gap junction channels, with certain "general" roles shared by all the channel...
      PubDate: 2012-12-17T18:14:10Z
       
  • Classical and desmosomal cadherins
    • Abstract: 1996
      Publication year: 1996
      Source:Advances in Structural Biology, Volume 4



      PubDate: 2012-12-17T18:14:10Z
       
  • Cytoskeleton and cell adhesion molecules in cell shape, growth regulation,
           and neoplasia
    • Abstract: 1996
      Publication year: 1996
      Source:Advances in Structural Biology, Volume 4



      PubDate: 2012-12-17T18:14:10Z
       
  • The cytoskeleton of the retinal pigment epithelium
    • Abstract: 1996
      Publication year: 1996
      Source:Advances in Structural Biology, Volume 4



      PubDate: 2012-12-17T18:14:10Z
       
  • Lung inflammation, fibrosis, and the concept of fibroblast heterogeneity
    • Abstract: 1996
      Publication year: 1996
      Source:Advances in Structural Biology, Volume 4



      PubDate: 2012-12-17T18:14:10Z
       
  • Fibrogenic and anti-fibrogenic factors in wound repair
    • Abstract: 1996
      Publication year: 1996
      Source:Advances in Structural Biology, Volume 4

      Much attention has been focused on the role of cytokines and growth factors in the orchestration of the normal processes of wound healing in recent years. It is now clear that wound healing requires many of these molecules to function as either mitogenic or fibrogenic agents, and as modulators of the cellular response, to coordinate the various aspects of regeneration and tissue repair. The quality of wound healing, however, may be compromised by abnormalities in the production, degradation, or activities of these growth factors, alone or in combination. There is now compelling evidence to suggest that the persistence of TGF-β and/or IGF-I at the site of injury may result in aberrations in wound healing, characterized by the pathological accumulation of ECM components. Therefore, controlling the activities of these factors, by the clinical application of antagonizing molecules could be the means by which the wound healing process may be regulated.

      PubDate: 2012-12-17T18:14:10Z
       
  • Antimicrobial mechanisms of activated macrophages and their induction by
           cytokines
    • Abstract: 1996
      Publication year: 1996
      Source:Advances in Structural Biology, Volume 4

      Macrophages are important modulators and effectors of immune responses in all vertebrates, and play a central role in host defense. Macrophages are normally quiescent cells, found in all tissues of the body, and are adapted to preforming specific activities within the microenvironments, of different tissues. However, when appropriately stimulated, macrophages rapidly become potent killer cells that efficiently eliminate foreign invaders. This process, termed macrophage activation, is a highly regulated event, requiring the precise coordination of antimicrobial mechanisms for effective elimination of pathogens, while minimizing damage to nearby host tissues. IFNγ is the most potent inducer of macrophage activation, and primes macrophages for enhanced antimicrobial responses. Other cytokines such as TNFα, IL-3, IL-4, IFNα, and IFNβ also prime macrophages for enhanced effector responses, but in most cases to a smaller degree than IFNγ. Activated macrophages must be appropriately triggered to kill pathogens. Microbial molecules, such as LPS, are potent trigger molecules of macrophage antimicrobial responses. Macrophages are not restricted to a single killing mechanism, but rather they possess an array of cytotoxic mechanisms, including the production of reactive oxygen and nitrogen intermediates, and the deprivation of essential growth nutrients such as iron and tryptophan. This elaborate killing response of activated macrophages is regulated and enhanced by different cytokines and/or metabolic products of the cytotoxic reactions. The overall result of these cytokine regulated host defenses is the removal of pathogens and a restoration of, homeostasis.

      PubDate: 2012-12-17T18:14:10Z
       
 
 
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