Publisher: Medip Academy   (Total: 12 journals)   [Sort by number of followers]

Showing 1 - 12 of 12 Journals sorted alphabetically
Intl. J. of Advances in Medicine     Open Access   (Followers: 2)
Intl. J. of Basic & Clinical Pharmacology     Open Access   (Followers: 2)
Intl. J. of Clinical Trials     Open Access   (Followers: 3)
Intl. J. of Community Medicine and Public Health     Open Access   (Followers: 7)
Intl. J. of Contemporary Pediatrics     Open Access   (Followers: 8)
Intl. J. of Otorhinolaryngology and Head and Neck Surgery     Open Access   (Followers: 1)
Intl. J. of Reproduction, Contraception, Obstetrics and Gynecology     Open Access   (Followers: 15)
Intl. J. of Research in Dermatology     Open Access   (Followers: 1)
Intl. J. of Research in Medical Sciences     Open Access   (Followers: 5)
Intl. J. of Research in Orthopaedics     Open Access  
Intl. J. of Scientific Reports     Open Access   (Followers: 4)
Intl. Surgery J.     Open Access   (Followers: 4)
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International Journal of Scientific Reports
Number of Followers: 4  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2454-2156 - ISSN (Online) 2454-2164
Published by Medip Academy Homepage  [12 journals]
  • Some medicinal plant from Kathmandu Valley, Central Nepal

    • Authors: Niroj Paudel, Mukti Ram Aryal, Bishnu Dev Das, Dinesh Chandra Adhikari, Prakash Deep Rai, Rajesh Shrestha
      Pages: 78 - 81
      Abstract: Background: This paper aims to explore distribution pattern of medicinal plants and their uses for the local communities. We have explained here 12 medicinal plants with their identification and medicinal uses.Methods: The plants were surveyed through the direct visit in a different interval of time after that plant was identified.  Results: 12 species were described as their medicinal value with identifying Characters. The knowledge of medicinal which provide the potential use for local communities.Conclusions: The Knowledge of the medicinal plant gives people as community as proper uses about the medicinal, herbs shrubs and tree. Due to this, we must preserve the plant as for future generation.
      PubDate: 2018-03-27
      Issue No: Vol. 4, No. 4 (2018)
  • Desert hedgehog knockout mice show a reduced ratio of CD4+:CD8+ in thymic
           developing T cells

    • Authors: Stephen Mwaura Kariuki
      Pages: 82 - 86
      Abstract: Background: Thymic differentiation is important and determines the strength of adaptive immunity in mammals in their later days in life. There are many factors that have been found to influence the development of T lymphocytes in the thymus and these include the effect of hedgehog signalling family of proteins. Immunologists and other basic science researchers have established the role of Indian hedgehog and sonic hedgehog in thymocytes development in the recent past, but the role of hedgehog is not well known. The aim of this study was to determine the influence of Desert hedgehog in CD4:CD8 ratio in developing thymocytes of mice.Methods: Smashed thymocytes from mice deficient of Desert hedgehog and those with an intact gene coding for this protein were prepared in a cell suspension using standard procedurs. The cell suspensions were stained using fluorochrome-labelled monoclonal anti: CD4-PE, CD8-TRI, CD3-FITC, CD5-FITC, CD44-PE and CD25-FITC (e-Bioscience). Samples were analyzed using a three-color flow cytometry. The flow cytometry-generated data was analyzed using flowjo (Treestar, USA). Statistical significance of the findings was determined using paired t-test and reported at p<0.05.  Results: There was a general upward trend on CD4+CD8+ double positive thymocytes in Desert hedgehog mice relative to WT controls. An analysis of CD4:8 ratio revealed a reduced ratio in Dhh KO mice compared to that of WT controls attributable to the finding that there might have been a preferential differentiation of DP CD4+CD8+ to SP CD4+ in Dhh knockout mice as demonstrated by percentage of thymic subsets. The results of this study were not statistically significant and this was blamed on the fewer number of animals used in the study.Conclusions: Dhh might have a role arresting the DP cell subjects from differentiating preferentially to CD4+ T cells. To get statistically significant findings, these experiments could be repeated with a larger animal sample.
      PubDate: 2018-03-27
      Issue No: Vol. 4, No. 4 (2018)
  • Assessment of knowledge, attitude and perceptions of HIV/AIDS among
           secondary school students in Guntur district of south India: a
           cross-sectional survey

    • Authors: Sai Krishna Gudi
      Pages: 87 - 92
      Abstract: Background: In recent years, there established a diverse information and accelerated surge towards HIV/AIDS. However, awareness of HIV/AIDS among children are ill-defined. As we all are familiar with the known fact that, our greatest natural resource is the minds of the young children who has the potentiality for forming a better nation. It is our greatest responsibility to ignite their young minds in order to eradicate the pandemic diseases such as HIV/AIDS. The objective of the study was to assess the knowledge, attitude and perceptions regarding HIV-AIDS among secondary school students.Methods: A cross-sectional survey was conducted using the simple random sampling technique. A total of 96 students aged between 13-17 years were sampled from a secondary school in Guntur district and interviewed through a validated self-administered questionnaire in order to assess the knowledge, attitude and perceptions (KAP) regarding HIV/AIDS. The study cohort includes students from VIII, IX, and X standards. Verbal consent from students was obtained before initiating the study. Responses were scored, analyzed and mean score and percentage were used to determine the level of KAP.  Results: The study results demonstrated that students of class X had a predominant overall knowledge than of class IX and VIII. While males had a good knowledge about HIV/AIDS. Whereas, females had a lot of misconceptions when compared on overall basis.Conclusions: This particular survey results strengthen the truth that still there exists a lack of awareness and knowledge among children regarding HIV/AIDS in developing countries like India.
      PubDate: 2018-03-27
      Issue No: Vol. 4, No. 4 (2018)
  • Prevalence and causes of visual impairment and blindness among school
           children in Muzaffarabad, Pakistan

    • Authors: Abdul Rauf Awan, Junaid Jamshed, Muhammad Mushtaq Khan, Zahid Latif
      Pages: 93 - 98
      Abstract: Background: Vision loss in childhood has serious implications in all stages of child’s growth and development. It poses social, educational and occupational challenges, with affected children being at greater risk of developing behavioral, psychological and emotional problems, lower self-esteem and poorer social integration. The aim of this study was to assess the prevalence and identify the causes of visual impairment and blindness in school children of UC Gojra, Muzaffarabad, Pakistan so that prevention strategies could be implemented.Methods: This was a school-based descriptive cross-sectional study conducted among public and private schools. A multi-stage stratified random sampling technique was used for selecting study participants aged 5-20 years from 24 schools in Muzaffarabad. The vision of school children was examined for visual acuity using standard Snellen chart. Those participants who had visual acuity of <6/18 in either eye underwent a more detailed ophthalmic examination to diagnose the causes of VI. An exploration of demographic variables was conducted using Chi-square test.  Results: The mean age of participants was 10±2.83. The prevalence of visual impairment was 19.6% and 2.3% for severe visual impairment. The age group most affected by VI was 11-15 years (74.2%). There were increased chances of developing VI with advancing age of the participants. Males contributed 88.7% of the cases of VI while females contributed only 11.3%. The class category 5-6 had higher percentage of VI cases (32.7%). Public schools contributed 52.8% of the cases of VI while for private schools the corresponding percentage was 47.2%. The leading cause of VI was refractive error (89.3%) followed by amblyopia (5.0%). Other causes of VI included cataract (1.2%), corneal disease (1.8%), strabismus (1.8%) and nystagmus (0.6%).Conclusions: There is a need to implement school health policy on visual screening prior to admissions in schools and annual eye screening program for early detection and prompt treatment of eye problems among school children in Muzaffarabad.
      PubDate: 2018-03-27
      Issue No: Vol. 4, No. 4 (2018)
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
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