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Publisher: Horizon Research Publishing   (Total: 54 journals)   [Sort by number of followers]

Showing 1 - 54 of 54 Journals sorted alphabetically
Advances in Diabetes and Metabolism     Open Access   (Followers: 23)
Advances in Economics and Business     Open Access   (Followers: 15)
Advances in Energy and Power     Open Access   (Followers: 16)
Advances in Pharmacology and Pharmacy     Open Access   (Followers: 6)
Advances in Signal Processing     Open Access   (Followers: 13)
Advances in Zoology and Botany     Open Access  
Bioengineering and Bioscience     Open Access   (Followers: 1)
Cancer and Oncology Research     Open Access   (Followers: 10)
Chemical and Materials Engineering     Open Access   (Followers: 23)
Civil Engineering and Architecture     Open Access   (Followers: 24)
Computational Research     Open Access   (Followers: 1)
Computer Science and Information Technology     Open Access   (Followers: 13)
Energy and Environmental Engineering     Open Access   (Followers: 7)
Environment and Ecology Research     Open Access   (Followers: 8)
Food Science and Technology     Open Access   (Followers: 3)
Immunology and Infectious Diseases     Open Access   (Followers: 9)
Intl. J. of Biochemistry and Biophysics     Open Access   (Followers: 1)
Intl. J. of Cardiovascular and Cerebrovascular Disease     Open Access   (Followers: 2)
Intl. J. of Neuroscience and Behavioral Science     Open Access   (Followers: 1)
Linguistics and Literature Studies     Open Access   (Followers: 4)
Manufacturing Science and Technology     Open Access   (Followers: 3)
Mathematics and Statistics     Open Access   (Followers: 5)
Nanoscience and Nanoengineering     Open Access   (Followers: 1)
Natural Resources and Conservation     Open Access   (Followers: 6)
Nursing and Health     Open Access   (Followers: 4)
Open J. of Dentistry and Oral Medicine     Open Access   (Followers: 1)
Sociology and Anthropology     Open Access   (Followers: 5)
Sport and Art     Open Access   (Followers: 1)
Universal J. of Accounting and Finance     Open Access   (Followers: 4)
Universal J. of Agricultural Research     Open Access   (Followers: 1)
Universal J. of Applied Mathematics     Open Access   (Followers: 5)
Universal J. of Applied Science     Open Access   (Followers: 2)
Universal J. of Biomedical Engineering     Open Access  
Universal J. of Chemistry     Open Access   (Followers: 1)
Universal J. of Clinical Medicine     Open Access  
Universal J. of Communications and Network     Open Access   (Followers: 1)
Universal J. of Computational Mathematics     Open Access   (Followers: 5)
Universal J. of Control and Automation     Open Access   (Followers: 4)
Universal J. of Educational Research     Open Access   (Followers: 1)
Universal J. of Electrical and Electronic Engineering     Open Access   (Followers: 6)
Universal J. of Engineering Science     Open Access   (Followers: 2)
Universal J. of Food and Nutrition Science     Open Access   (Followers: 5)
Universal J. of Geoscience     Open Access   (Followers: 4)
Universal J. of Industrial and Business Management     Open Access   (Followers: 1)
Universal J. of Management     Open Access   (Followers: 2)
Universal J. of Materials Science     Open Access   (Followers: 3)
Universal J. of Mechanical Engineering     Open Access   (Followers: 16)
Universal J. of Medical Science     Open Access  
Universal J. of Microbiology Research     Open Access  
Universal J. of Physics and Application     Open Access   (Followers: 2)
Universal J. of Plant Science     Open Access  
Universal J. of Psychology     Open Access   (Followers: 3)
Universal J. of Public Health     Open Access   (Followers: 2)
World J. of Computer Application and Technology     Open Access   (Followers: 4)
Journal Cover
Cancer and Oncology Research
Number of Followers: 10  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2331-6128 - ISSN (Online) 2331-6136
Published by Horizon Research Publishing Homepage  [54 journals]
  • Window-of-opportunity Study Testing the Antiproliferative Effect of
           Atorvastatin in Egyptian Patients with Operable Breast Cancer

    • Abstract: Publication date:  Nov 2017
      Source:Cancer and Oncology Research  Volume  5  Number  4  Bader A. Abdelmaksoud   Mohamed I. Abdelhamid   Salah Abd Elaal   and Hayam E. Rashed   Background and purpose: Cholesterol-lowering drugs (statins) appear to have pleiotropic effects independent of cholesterol level. The aim of this study was to assess the effect of pre-operative therapy with a statin (atorvastatin) on tumor proliferation in patients with newly diagnosed breast cancer. Methods: Thirty cases with histologically proven breast cancer were subjected to treatment by atorvastatin 80 mg /day for at least 14 days before the final surgical procedure (MRM or BCS). Immunohistochemical expression of Ki-67 staining of breast tumor cells was evaluated to assess tumor proliferation in biopsy tissues before treatment with atorvastatin then in final surgical tissues specimens. Results: The median age of the patients was 49.5 ranging from 29 to 61 years. The vast majority of the patients had invasive duct carcinoma (IDC) and was positive for estrogen and progesterone receptors. The mean pretreatment Ki67 index was high in the majority of patients and was significantly associated with both tumor grade and estrogen receptor status (P = 0.001 and P= 0.003, respectively). The Ki67 index had decreased in the post-treatment samples after final surgery in 19 cases, increased in 8 cases and unchanged in 3 cases compared to the pre-treatment specimens. Tumor grade is a significant predictor of treatment response (p=0,05). Conclusion: Atorvastatin decreased tumor proliferation in breast cancer especially in high grade tumors and its role should be considered in the future studies.
      PubDate: Nov 2017
  • Similarities in Asymptomatic HIV Infection and Cancer: A Common 'Driver'

    • Abstract: Publication date:  Jun 2017
      Source:Cancer and Oncology Research  Volume  5  Number  2  Mburu Samuel   Cancer and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) are associated with chronic oxidative stress, inflammation and immune activation either as a consequence or a cause. Despite well documented characteristic similarities in the two diseases, this has not been exploited for better understanding of carcinogenesis. The purpose of this descriptive study was to review existing studies for knowledge, research gaps in the role of oxidative stress, inflammation, immune activation in cancer and asymptomatic HIV infection; identify similarities, differences to stimulate new research ideas which can accelerate future therapeutic target discoveries. PubMed, ScienceDirect and Google scholar databases were searched using the keywords: oxidative stress, inflammation, immune activation, cancer and asymptomatic HIV infection. Little research has been done on immune evasion, tolerance and oxidative stress-induced inflammation and immune activation as therapeutic targets in both diseases. Senescence and the role of respiratory burst in HIV infection have not been exhaustively studied. Out of a total of 15,788,387 hits, 15, 284,572 hits related to similarities with only 503, 815 relating to the differences between the two diseases. Consequently and after pearling, 89 articles that were directly relevant to the study were selected. After critical appraisal, the identified studies were analyzed, results compared and presented in form of summary tables. Results indicated that chronic oxidative stress, inflammation and immune activation were common drivers of progression in the two diseases. Therefore, better understanding of these drivers might provide new mechanistic insights in carcinogenesis and provide future novel therapeutic targets. This will support the United Nations sustainable development goal (SDG) number 3 on ensuring health lives and promoting well-being for all at all ages.
      PubDate: Jun 2017
  • The Measurement of Delay in Diagnosis and Treatment among Moroccan Women
           with Cervical Cancer

    • Abstract: Publication date:  Feb 2017
      Source:Cancer and Oncology Research  Volume  5  Number  1  Fatima Ouasmani   Zaki Hanchi   Bouchra Haddou Rahou   Rachid Bekkali   Bouchra Benazzouz   and Abdelhalem Mesfioui   In Morocco, most of the cervical cancer patients have been reported diagnosed at advanced stage indicating delay in seeking diagnosis and treatment. The main purpose of this investigation was to measure the delay from the first symptom to treatment among Moroccan women with cervical cancer. Methods: We conducted a cross-sectional study at the National Institute of Oncology Sidi Mohammed Ben Abdellah in Rabat, Morocco. A consecutive series of patients with locally advanced cervical cancer or metastasic [stage II-IV] were recruited. We calculated delay by using two events dates of two periods in patient's pathway. Multivariate binary logistic regression analysis was performed to measure the association between all categories of delay and magnitude of total delay. Results: Four hundred and one patients were reached in this study. The median total delay was 183 days, the median patient delay was 120 days, the median diagnosis delay was 110 days, and the median Treatment delay was 57 days. Bivariate analysis showed that patients who did not have respectively patient and diagnosis delay were less likely to have total delay (p
      PubDate: Feb 2017
  • Self-reported Use of Complementary and Alternative Medicine among Moroccan
           Women with Breast Cancer

    • Abstract: Publication date:  Feb 2017
      Source:Cancer and Oncology Research  Volume  5  Number  1  Bouchra Haddou Rahou   Karima El Rhazi   Zaki Hanchi   Fatima Ouasmani   Bouchra Benazzouz   and Abdelhalem Mesfioui   The objective of this study was to assess the prevalence, types, sociodemographic and clinical-related factors of complementary and alternative medicine use among Moroccan women with breast cancer. A cross-sectional study was carried out at the National Institute of Oncology in Rabat. 400 patients with breast cancer were recruited for face-to-face interviews. Data were collected using a questionnaire addressing personal/medical characteristics and the use of CAM therapies. 88.5% of women used at least one CAM therapy, 73.2% of them reported began to use CAM at the onset of breast cancer symptoms. Type of CAM commonly used were prayers, listening and/or reading the Koran and use of naturel products like honey or fenugreek. High education level was independent factors related to CAM use. Interventions should be focused on open communication and further researches are needed to explore the safety and the outcome of CAM use.
      PubDate: Feb 2017
  • Towards a Personalized Cancer Gene Therapy: A Case of Clear Cell Renal
           Cell Carcinoma

    • Abstract: Publication date:  Aug 2017
      Source:Cancer and Oncology Research  Volume  5  Number  3  Dumitru Andrei Iacobas   and Sanda Iacobas   An ideal cancer gene therapy would selectively destroy the cancer nodules with negligible effects on the surrounding not yet compromised tissue. This would be possible if the targeted genes are in command positions in the cancer but not in the normal cells. Logic dictates that, while being strongly protected by the homeostatic mechanisms, expression of a commander gene governs most major functional pathways by regulating the expression of numerous other genes. Owing to the cancer dependence on race, sex, age, genetic heritage, medical history, environmental and lifestyle associated risk factors each patient has most likely a distinct, dynamic and never repeatable set of commander genes. Here we introduce the "gene commanding height" as a measure of gene rank in the cell hierarchy and test our procedure on a surgically removed metastatic clear cell renal cell carcinoma. Results indicate that each histopathologically distinct region has a unique set of commander genes and that cancer cell commanders are in low positions in normal cells. We believe that the genomic oncology should identify the cancer cell commander genes of the individual patient instead of testing for the biomarkers selected from most frequently altered genes in large populations.
      PubDate: Aug 2017
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
Tel: +00 44 (0)131 4513762
Fax: +00 44 (0)131 4513327
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