Publisher: Cambridge University Press   (Total: 387 journals)

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Showing 201 - 387 of 387 Journals sorted alphabetically
J. of British Studies     Full-text available via subscription   (Followers: 34, SJR: 0.246, CiteScore: 0)
J. of Child Language     Hybrid Journal   (Followers: 30, SJR: 1.035, CiteScore: 2)
J. of Chinese History / 中國歷史學刊     Hybrid Journal  
J. of Classics Teaching     Open Access  
J. of Clinical and Translational Science     Open Access  
J. of Dairy Research     Full-text available via subscription   (Followers: 8, SJR: 0.573, CiteScore: 1)
J. of Demographic Economics     Hybrid Journal   (Followers: 3, SJR: 1.227, CiteScore: 1)
J. of Developmental Origins of Health and Disease     Hybrid Journal   (Followers: 2, SJR: 0.843, CiteScore: 2)
J. of Diagnostic Radiography and Imaging     Hybrid Journal   (Followers: 4)
J. of East Asian Studies     Full-text available via subscription   (Followers: 17, SJR: 0.59, CiteScore: 1)
J. of Ecclesiastical History     Hybrid Journal   (Followers: 19, SJR: 0.138, CiteScore: 0)
J. of Economic History     Full-text available via subscription   (Followers: 47, SJR: 1.82, CiteScore: 2)
J. of Experimental Political Science     Full-text available via subscription   (Followers: 7, SJR: 2.526, CiteScore: 2)
J. of Financial and Quantitative Analysis     Full-text available via subscription   (Followers: 50, SJR: 3.636, CiteScore: 2)
J. of Fluid Mechanics     Hybrid Journal   (Followers: 193, SJR: 1.591, CiteScore: 3)
J. of French Language Studies     Hybrid Journal   (Followers: 7, SJR: 0.163, CiteScore: 0)
J. of Functional Programming     Hybrid Journal   (Followers: 1, SJR: 0.458, CiteScore: 1)
J. of Germanic Linguistics     Full-text available via subscription   (Followers: 8, SJR: 0.157, CiteScore: 0)
J. of Global History     Full-text available via subscription   (Followers: 30, SJR: 0.34, CiteScore: 1)
J. of Hellenic Studies     Full-text available via subscription   (Followers: 19, SJR: 0.146, CiteScore: 0)
J. of Helminthology     Hybrid Journal   (Followers: 2, SJR: 0.553, CiteScore: 1)
J. of Hospitality and Tourism Management     Full-text available via subscription   (Followers: 14, SJR: 0.949, CiteScore: 2)
J. of Institutional Economics     Hybrid Journal   (Followers: 15, SJR: 0.978, CiteScore: 2)
J. of K-Theory     Full-text available via subscription  
J. of Laryngology & Otology     Hybrid Journal   (Followers: 21, SJR: 0.495, CiteScore: 1)
J. of Latin American Studies     Hybrid Journal   (Followers: 33, SJR: 0.34, CiteScore: 1)
J. of Law and Religion     Full-text available via subscription   (Followers: 10, SJR: 0.115, CiteScore: 0)
J. of Linguistic Geography     Full-text available via subscription   (Followers: 1)
J. of Linguistics     Hybrid Journal   (Followers: 18, SJR: 0.451, CiteScore: 1)
J. of Management & Organization     Full-text available via subscription   (Followers: 350, SJR: 0.543, CiteScore: 1)
J. of Mechanics     Hybrid Journal   (Followers: 21, SJR: 0.303, CiteScore: 1)
J. of Modern African Studies     Hybrid Journal   (Followers: 20, SJR: 0.606, CiteScore: 1)
J. of Navigation     Hybrid Journal   (Followers: 254, SJR: 0.493, CiteScore: 2)
J. of Nutritional Science     Open Access   (Followers: 3, SJR: 0.984, CiteScore: 2)
J. of Pacific Rim Psychology     Hybrid Journal   (Followers: 1, SJR: 0.33, CiteScore: 1)
J. of Paleontology     Hybrid Journal   (Followers: 11, SJR: 0.882, CiteScore: 2)
J. of Pension Economics & Finance     Hybrid Journal   (Followers: 7, SJR: 0.931, CiteScore: 1)
J. of Plasma Physics     Hybrid Journal   (Followers: 23, SJR: 0.441, CiteScore: 1)
J. of Psychiatric Intensive Care     Hybrid Journal   (Followers: 8)
J. of Psychologists and Counsellors in Schools     Full-text available via subscription   (Followers: 8, SJR: 0, CiteScore: 1)
J. of Public Policy     Hybrid Journal   (Followers: 27, SJR: 0.542, CiteScore: 1)
J. of Race, Ethnicity, and Politics     Full-text available via subscription   (Followers: 4)
J. of Radiotherapy in Practice     Hybrid Journal   (Followers: 7, SJR: 0.16, CiteScore: 0)
J. of Relationships Research     Hybrid Journal   (Followers: 5, SJR: 0.294, CiteScore: 0)
J. of Roman Archaeology     Hybrid Journal   (Followers: 22, SJR: 0.341, CiteScore: 1)
J. of Roman Studies     Full-text available via subscription   (Followers: 22, SJR: 0.182, CiteScore: 0)
J. of Smoking Cessation     Hybrid Journal   (Followers: 6, SJR: 0.411, CiteScore: 0)
J. of Social Policy     Hybrid Journal   (Followers: 41, SJR: 1.063, CiteScore: 2)
J. of Southeast Asian Studies     Full-text available via subscription   (Followers: 12, SJR: 0.14, CiteScore: 0)
J. of Symbolic Logic     Hybrid Journal   (Followers: 1, SJR: 1.057, CiteScore: 1)
J. of the American Philosophical Association     Hybrid Journal   (SJR: 0.857, CiteScore: 1)
J. of the Australian Mathematical Society     Full-text available via subscription   (SJR: 0.46, CiteScore: 1)
J. of the Gilded Age and Progressive Era     Full-text available via subscription   (Followers: 8, SJR: 0.192, CiteScore: 0)
J. of the History of Economic Thought     Full-text available via subscription   (Followers: 14, SJR: 0.784, CiteScore: 1)
J. of the Institute of Mathematics of Jussieu     Hybrid Journal   (SJR: 2.393, CiteScore: 1)
J. of the Intl. Neuropsychological Society     Hybrid Journal   (Followers: 15, SJR: 1.408, CiteScore: 3)
J. of the Intl. Phonetic Association     Full-text available via subscription   (Followers: 2, SJR: 0.27, CiteScore: 1)
J. of the Marine Biological Association of the UK     Hybrid Journal   (Followers: 23, SJR: 0.548, CiteScore: 1)
J. of the Royal Asiatic Society     Hybrid Journal   (Followers: 14, SJR: 0.121, CiteScore: 0)
J. of the Society for American Music     Hybrid Journal   (Followers: 10, SJR: 0.199, CiteScore: 0)
J. of Tropical Ecology     Hybrid Journal   (Followers: 14, SJR: 0.626, CiteScore: 1)
J. of Tropical Psychology     Hybrid Journal   (Followers: 1)
J. of Wine Economics     Full-text available via subscription   (Followers: 5)
Japanese J. of Political Science     Hybrid Journal   (Followers: 8, SJR: 0.372, CiteScore: 1)
Kantian Review     Full-text available via subscription   (Followers: 3)
Knowledge Engineering Review     Hybrid Journal   (Followers: 2, SJR: 0.357, CiteScore: 2)
Language and Cognition     Hybrid Journal   (Followers: 22)
Language in Society     Hybrid Journal   (Followers: 22, SJR: 1.466, CiteScore: 2)
Language Teaching     Hybrid Journal   (Followers: 33, SJR: 1.233, CiteScore: 2)
Language Variation and Change     Hybrid Journal   (Followers: 9, SJR: 0.854, CiteScore: 1)
Laser and Particle Beams     Hybrid Journal   (Followers: 2, SJR: 0.497, CiteScore: 1)
Law and History Review     Full-text available via subscription   (Followers: 15, SJR: 0.184, CiteScore: 0)
Legal Information Management     Hybrid Journal   (Followers: 10)
Legal Theory     Hybrid Journal   (Followers: 14, SJR: 0.484, CiteScore: 1)
Leiden J. of Intl. Law     Hybrid Journal   (Followers: 39, SJR: 0.482, CiteScore: 0)
Libyan Studies     Hybrid Journal   (Followers: 1, SJR: 0.111, CiteScore: 0)
LMS J. of Computation and Mathematics     Free   (SJR: 0.229, CiteScore: 1)
Macroeconomic Dynamics     Hybrid Journal   (Followers: 25, SJR: 1.169, CiteScore: 1)
Management and Organization Review     Hybrid Journal   (Followers: 12, SJR: 0.816, CiteScore: 2)
Mathematical Proceedings of the Cambridge Philosophical Society     Full-text available via subscription   (Followers: 1, SJR: 1.086, CiteScore: 1)
Mathematical Structures in Computer Science     Hybrid Journal   (Followers: 3, SJR: 0.298, CiteScore: 1)
Medical History     Hybrid Journal   (Followers: 8, SJR: 0.417, CiteScore: 1)
Microscopy and Microanalysis     Full-text available via subscription   (Followers: 2, SJR: 0.292, CiteScore: 0)
Modern Asian Studies     Hybrid Journal   (Followers: 16, SJR: 0.397, CiteScore: 0)
Modern Intellectual History     Hybrid Journal   (Followers: 16, SJR: 0.218, CiteScore: 0)
MRS Communications     Hybrid Journal   (SJR: 1.443, CiteScore: 3)
MRS Energy & Sustainability - A Review J.     Full-text available via subscription  
Nagoya Mathematical J.     Hybrid Journal   (SJR: 0.892, CiteScore: 1)
Natural Language Engineering     Hybrid Journal   (Followers: 4, SJR: 0.264, CiteScore: 1)
Netherlands J. of Geosciences     Hybrid Journal   (SJR: 0.285, CiteScore: 1)
Netherlands Yearbook of Intl. Law     Full-text available via subscription   (Followers: 15, SJR: 0.196, CiteScore: 0)
Network Science     Hybrid Journal   (Followers: 5, SJR: 0.461, CiteScore: 1)
Neuron Glia Biology     Hybrid Journal  
New Perspectives on Turkey     Full-text available via subscription   (Followers: 3, SJR: 0.111, CiteScore: 0)
New Surveys in the Classics     Full-text available via subscription   (Followers: 3)
New Testament Studies     Hybrid Journal   (Followers: 33, SJR: 0.316, CiteScore: 0)
New Theatre Quarterly     Hybrid Journal   (Followers: 15, SJR: 0.132, CiteScore: 0)
Nineteenth-Century Music Review     Hybrid Journal   (Followers: 6, SJR: 0.1, CiteScore: 0)
Nordic J. of Linguistics     Hybrid Journal   (Followers: 8, SJR: 0.156, CiteScore: 0)
Numerical Mathematics : Theory, Methods and Applications     Full-text available via subscription  
Nurse Prescriber     Full-text available via subscription   (Followers: 5)
Nutrition Research Reviews     Hybrid Journal   (Followers: 13, SJR: 1.756, CiteScore: 5)
Organised Sound     Hybrid Journal   (Followers: 8, SJR: 0.271, CiteScore: 0)
Oryx     Hybrid Journal   (Followers: 19, SJR: 0.981, CiteScore: 2)
Paleobiology     Full-text available via subscription   (Followers: 6, SJR: 1.563, CiteScore: 3)
Palliative & Supportive Care     Hybrid Journal   (Followers: 34, SJR: 0.611, CiteScore: 1)
Papers of the British School at Rome     Full-text available via subscription   (Followers: 19, SJR: 0.13, CiteScore: 0)
Parasitology     Hybrid Journal   (Followers: 4, SJR: 1.194, CiteScore: 2)
Parasitology Open     Open Access  
Personality Neuroscience     Open Access  
Perspectives on Politics     Full-text available via subscription   (Followers: 42, SJR: 2.075, CiteScore: 2)
Philosophy     Full-text available via subscription   (Followers: 14, SJR: 0.331, CiteScore: 0)
Phonology     Hybrid Journal   (Followers: 9, SJR: 0.623, CiteScore: 1)
Plainsong and Medieval Music     Hybrid Journal   (Followers: 8, SJR: 0.114, CiteScore: 0)
Plant Genetic Resources     Hybrid Journal   (Followers: 3, SJR: 0.353, CiteScore: 1)
Polar Record     Hybrid Journal   (Followers: 2, SJR: 0.313, CiteScore: 1)
Political Science Research and Methods     Full-text available via subscription   (Followers: 22)
Politics & Gender     Full-text available via subscription   (Followers: 25, SJR: 0.861, CiteScore: 1)
Politics and Religion     Full-text available via subscription   (Followers: 9, SJR: 0.541, CiteScore: 1)
Popular Music     Hybrid Journal   (Followers: 20, SJR: 0.216, CiteScore: 0)
Powder Diffraction     Full-text available via subscription   (Followers: 1, SJR: 0.319, CiteScore: 1)
Prehospital and Disaster Medicine     Full-text available via subscription   (Followers: 9, SJR: 0.462, CiteScore: 1)
Primary Health Care Research & Development     Open Access   (Followers: 18, SJR: 0.52, CiteScore: 1)
Probability in the Engineering and Informational Sciences     Hybrid Journal   (Followers: 1, SJR: 0.406, CiteScore: 1)
Proceedings of the Edinburgh Mathematical Society     Hybrid Journal   (SJR: 0.695, CiteScore: 1)
Proceedings of the Intl. Astronomical Union     Full-text available via subscription   (Followers: 2, SJR: 0.117, CiteScore: 0)
Proceedings of the Nutrition Society     Hybrid Journal   (Followers: 8, SJR: 1.373, CiteScore: 4)
Proceedings of the Prehistoric Society     Hybrid Journal   (Followers: 9)
Proceedings of the Royal Society of Edinburgh Section A Mathematics     Full-text available via subscription   (SJR: 1.506, CiteScore: 1)
Progress in Neurotherapeutics and Neuropsychopharmacology     Full-text available via subscription  
PS: Political Science & Politics     Full-text available via subscription   (Followers: 38, SJR: 0.665, CiteScore: 1)
Psychological Medicine     Hybrid Journal   (Followers: 18, SJR: 3.274, CiteScore: 5)
Public Health Nutrition     Hybrid Journal   (Followers: 23, SJR: 1.122, CiteScore: 2)
Publications of the Astronomical Society of Australia     Hybrid Journal   (Followers: 2, SJR: 1.237, CiteScore: 2)
Quarterly Reviews of Biophysics     Hybrid Journal   (Followers: 3, SJR: 3.282, CiteScore: 6)
Quaternary Research     Full-text available via subscription   (Followers: 19, SJR: 1.216, CiteScore: 2)
Queensland Review     Full-text available via subscription   (SJR: 0.101, CiteScore: 0)
Radiocarbon     Hybrid Journal   (Followers: 9, SJR: 0.959, CiteScore: 2)
Ramus : Critical Studies in Greek and Roman Literature     Hybrid Journal   (Followers: 5, SJR: 0.201, CiteScore: 0)
ReCALL     Hybrid Journal   (Followers: 4, SJR: 2.813, CiteScore: 3)
Religious Studies     Hybrid Journal   (Followers: 12, SJR: 0.172, CiteScore: 0)
Renewable Agriculture and Food Systems     Hybrid Journal   (Followers: 15, SJR: 0.593, CiteScore: 2)
Review of Intl. Studies     Full-text available via subscription   (Followers: 27, SJR: 1.63, CiteScore: 2)
Review of Middle East Studies     Full-text available via subscription   (Followers: 10, SJR: 0.101, CiteScore: 0)
Review of Politics     Full-text available via subscription   (Followers: 5, SJR: 0.119, CiteScore: 0)
Review of Symbolic Logic     Full-text available via subscription   (Followers: 2, SJR: 1.049, CiteScore: 1)
Reviews in Clinical Gerontology     Hybrid Journal   (Followers: 5)
Revista de Historia Económica     Full-text available via subscription   (Followers: 1, SJR: 0.221, CiteScore: 0)
Revista Internacional de la Cruz Roja     Full-text available via subscription   (Followers: 2)
Robotica     Hybrid Journal   (Followers: 3, SJR: 0.375, CiteScore: 1)
Royal Institute of Philosophy Supplements     Full-text available via subscription   (Followers: 4)
Rural History     Hybrid Journal   (Followers: 14, SJR: 0.145, CiteScore: 0)
Science in Context     Hybrid Journal   (Followers: 3, SJR: 0.265, CiteScore: 0)
Scottish J. of Theology     Hybrid Journal   (Followers: 38, SJR: 0.177, CiteScore: 0)
Seed Science Research     Hybrid Journal   (Followers: 2, SJR: 0.95, CiteScore: 2)
Slavic Review     Hybrid Journal   (Followers: 8, SJR: 0.395, CiteScore: 1)
Social Philosophy and Policy     Full-text available via subscription   (Followers: 22, SJR: 0.253, CiteScore: 1)
Social Policy and Society     Hybrid Journal   (Followers: 188, SJR: 0.653, CiteScore: 1)
Social Science History     Full-text available via subscription   (Followers: 16, SJR: 0.2, CiteScore: 0)
Spanish J. of Psychology     Hybrid Journal  
Studies in American Political Development     Hybrid Journal   (Followers: 6, SJR: 0.204, CiteScore: 0)
Studies in Church History     Full-text available via subscription   (Followers: 1)
Studies in Second Language Acquisition     Hybrid Journal   (Followers: 41, SJR: 1.516, CiteScore: 2)
Tempo     Hybrid Journal   (Followers: 2, SJR: 0.151, CiteScore: 0)
Thalamus & Related Systems     Full-text available via subscription  
The Americas : A Quarterly Review of Latin American History     Full-text available via subscription   (Followers: 5, SJR: 0.305, CiteScore: 0)
The Lichenologist     Hybrid Journal   (Followers: 5, SJR: 1.113, CiteScore: 2)
The Mathematical Gazette     Full-text available via subscription   (Followers: 1)
Theatre Research Intl.     Full-text available via subscription   (Followers: 14, SJR: 0.204, CiteScore: 0)
Theatre Survey     Full-text available via subscription   (Followers: 11, SJR: 0.121, CiteScore: 0)
Theory and Practice of Logic Programming     Hybrid Journal   (Followers: 3, SJR: 0.524, CiteScore: 2)
Think     Full-text available via subscription   (Followers: 6)
TRaNS : Trans-Regional-and-National Studies of Southeast Asia     Full-text available via subscription   (Followers: 6, SJR: 0.192, CiteScore: 0)
Transactions of the Royal Historical Society     Hybrid Journal   (Followers: 15, SJR: 0.419, CiteScore: 0)
Transnational Environmental Law     Hybrid Journal   (Followers: 5, SJR: 0.498, CiteScore: 1)
Twentieth-century music     Hybrid Journal   (Followers: 4, SJR: 0.453, CiteScore: 1)
Twin Research and Human Genetics     Full-text available via subscription   (SJR: 0.72, CiteScore: 1)
Urban History     Hybrid Journal   (Followers: 18, SJR: 0.358, CiteScore: 0)
Utilitas     Hybrid Journal   (Followers: 8, SJR: 0.712, CiteScore: 0)
Victorian Literature and Culture     Hybrid Journal   (Followers: 21, SJR: 0.163, CiteScore: 0)
Visual Neuroscience     Hybrid Journal   (Followers: 7, SJR: 1.012, CiteScore: 2)
Wireless Power Transfer     Full-text available via subscription   (Followers: 4)
World Politics     Hybrid Journal   (Followers: 213, SJR: 6.544, CiteScore: 4)
World Trade Review     Full-text available via subscription   (Followers: 17, SJR: 0.591, CiteScore: 1)
World's Poultry Science J.     Full-text available via subscription   (Followers: 5, SJR: 0.559, CiteScore: 1)
Yearbook of Intl. Humanitarian Law     Full-text available via subscription   (Followers: 8, SJR: 0.107, CiteScore: 0)
Zygote     Hybrid Journal   (Followers: 1, SJR: 0.387, CiteScore: 1)

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Similar Journals
Journal Cover
Proceedings of the Nutrition Society
Journal Prestige (SJR): 1.373
Citation Impact (citeScore): 4
Number of Followers: 8  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 0029-6651 - ISSN (Online) 1475-2719
Published by Cambridge University Press Homepage  [387 journals]
  • PNS volume 79 issue 2 Cover and Front matter
    • PubDate: 2020-05-01T00:00:00.000Z
      DOI: 10.1017/S0029665120000130
      Issue No: Vol. 79, No. 2 (2020)
       
  • PNS volume 79 issue 2 Cover and Back matter
    • PubDate: 2020-05-01T00:00:00.000Z
      DOI: 10.1017/S0029665120000142
      Issue No: Vol. 79, No. 2 (2020)
       
  • Inter-individual differences in the nutrition response: from research to
           recommendations
    • Authors: Joanne E. Cecil; Karen L. Barton
      Pages: 171 - 173
      Abstract: The 2019 Nutrition Society Spring Conference, which convened in Dundee, focused on the challenges presented by inter-individual differences in the responses to nutrition and in conducting nutritional research. The programme brought together national and international experts to discuss the collective evidence on inter-individual nutritional responses and impacts on health. Speakers and delegates from across the UK, Europe and the USA debated new methods of conducting research in nutrition and discussed the development of appropriate dietary interventions to maintain health and prevent disease in diverse populations. Symposium 1 focused on the effects of ethnicity on nutrient availability and type 2 diabetes and cardio-metabolic disease. Symposium 2 explored sex differences in nutrient availability and health and metabolism. The final symposium examined genetic and phenotypic variation, nutrition and health. The meeting ended with a panel discussion about how we take research to recommendations and concluded with a need to consider inter-individual differences in planning, conducting and analysing nutritional research.
      PubDate: 2020-05-01T00:00:00.000Z
      DOI: 10.1017/S0029665119001198
      Issue No: Vol. 79, No. 2 (2020)
       
  • Challenges of the heterogeneous nutrition response: interpreting the group
           mean
    • Authors: Janice E. Drew
      Pages: 174 - 183
      Abstract: Extensive research demonstrates unequivocally that nutrition plays a fundamental role in maintaining health and preventing disease. In parallel nutrition research provides evidence that the risks and benefits of diet and lifestyle choices do not affect people equally, as people are inherently variable in their responses to nutrition and associated interventions to maintain health and prevent disease. To simplify the inherent complexity of human subjects and their nutrition, with the aim of managing expectations for dietary guidance required to ensure healthy populations and individuals, nutrition researchers often seek to group individuals based on commonly used criteria. This strategy relies on demonstrating meaningful conclusions based on comparison of group mean responses of assigned groups. Such studies are often confounded by the heterogeneous nutrition response. Commonly used criteria applied in grouping study populations and individuals to identify mechanisms and determinants of responses to nutrition often contribute to the problem of interpreting the results of group comparisons. Challenges of interpreting the group mean using diverse populations will be discussed with respect to studies in human subjects, in vivo and in vitro model systems. Future advances in nutrition research to tackle inter-individual variation require a coordinated approach from funders, learned societies, nutrition scientists, publishers and reviewers of the scientific literature. This will be essential to develop and implement improved study design, data recording, analysis and reporting to facilitate more insightful interpretation of the group mean with respect to population diversity and the heterogeneous nutrition response.
      PubDate: 2020-05-01T00:00:00.000Z
      DOI: 10.1017/S002966511900096X
      Issue No: Vol. 79, No. 2 (2020)
       
  • Ethnic distinctions in the pathophysiology of type 2 diabetes: a focus on
           black African-Caribbean populations
    • Authors: Louise M. Goff; Meera Ladwa, Olah Hakim, Oluwatoyosi Bello
      Pages: 184 - 193
      Abstract: Type 2 diabetes (T2D) is a global public health priority, particularly for populations of black African-Caribbean ethnicity, who suffer disproportionately high rates of the disease. While the mechanisms underlying the development of T2D are well documented, there is growing evidence describing distinctions among black African-Caribbean populations. In the present paper, we review the evidence describing the impact of black African-Caribbean ethnicity on T2D pathophysiology. Ethnic differences were first recognised through evidence that metabolic syndrome diagnostic criteria fail to detect T2D risk in black populations due to less central obesity and dyslipidaemia. Subsequently more detailed investigations have recognised other mechanistic differences, particularly lower visceral and hepatic fat accumulation and a distinctly hyperinsulinaemic response to glucose stimulation. While epidemiological studies have reported exaggerated insulin resistance in black populations, more detailed and direct measures of insulin sensitivity have provided evidence that insulin sensitivity is not markedly different to other ethnic groups and does not explain the hyperinsulinaemia that is exhibited. These findings lead us to hypothesise that ectopic fat does not play a pivotal role in driving insulin resistance in black populations. Furthermore, we hypothesise that hyperinsulinaemia is driven by lower rates of hepatic insulin clearance rather than heightened insulin resistance and is a primary defect rather than occurring in compensation for insulin resistance. These hypotheses are being investigated in our ongoing South London Diabetes and Ethnicity Phenotyping study, which will enable a more detailed understanding of ethnic distinctions in the pathophysiology of T2D between men of black African and white European ethnicity.
      PubDate: 2020-05-01T00:00:00.000Z
      DOI: 10.1017/S0029665119001034
      Issue No: Vol. 79, No. 2 (2020)
       
  • A nutrigenetics approach to study the impact of genetic and lifestyle
           factors on cardiometabolic traits in various ethnic groups: findings from
           the GeNuIne Collaboration
    • Authors: Karani S. Vimaleswaran
      Pages: 194 - 204
      Abstract: Several studies on gene–diet interactions (nutrigenetics) have been performed in western populations; however, there are only a few studies to date in lower middle-income countries (LMIC). A large-scale collaborative project called gene–nutrient interactions (GeNuIne) Collaboration, the main objective of which is to investigate the effect of GeNuIne on cardiometabolic traits using population-based studies from various ethnic groups, has been initiated at the University of Reading, UK. While South Asians with higher genetic risk score (GRS) showed a higher risk of obesity in response to a high-carbohydrate diet, South East and Western Asian populations with higher GRS showed an increased risk of central obesity in response to a high-protein diet. The paper also provides a summary of other gene–diet interaction analyses that were performed in LMIC as part of this collaborative project and gives an overview of how these nutrigenetic findings can be translated to personalised and public health approaches for the prevention of cardiometabolic diseases such as obesity, type 2 diabetes and CVD.
      PubDate: 2020-05-01T00:00:00.000Z
      DOI: 10.1017/S0029665119001186
      Issue No: Vol. 79, No. 2 (2020)
       
  • Sex matters: a focus on the impact of biological sex on metabolomic
           profiles and dietary interventions
    • Authors: Lorraine Brennan; Helena Gibbons
      Pages: 205 - 209
      Abstract: The metabolomic profile of a biofluid can be altered by dietary intake, exercise and disease processes and, thus provides an important tool for the study of many physiological processes. However, in addition to perturbation due to disease, the metabolomic profile of urine and plasma has also been shown to vary due to many intrinsic physiological factors such as age, sex, hormonal status and diurnal variation. Characterisation of this normal degree of variation in the metabolomic profiles of human biofluids is a necessary and important step in the development of metabolomics for use in nutrition-related research. The current review focuses on the impact of sex on the metabolomic profile. A number of studies have reported that sex impacts metabolites such as amino acids, lipids, sugars and keto acids. Furthermore, we examine the effect of the menstrual cycle on the metabolomic profile. Responses to dietary interventions can also differ between the sexes and highlighting this is important for the development of the field of precision nutrition.
      PubDate: 2020-05-01T00:00:00.000Z
      DOI: 10.1017/S002966511900106X
      Issue No: Vol. 79, No. 2 (2020)
       
  • Different physiological mechanisms underlie an adverse cardiovascular
           disease risk profile in men and women
    • Authors: Alan Fappi; Bettina Mittendorfer
      Pages: 210 - 218
      Abstract: CVD affect about one-third of the population and are the leading cause of mortality. The prevalence of CVD is closely linked to the prevalence of obesity because obesity is commonly associated with metabolic abnormalities that are important risk factors for CVD, including insulin resistance, pre-diabetes, and type-2 diabetes, atherosclerotic dyslipidaemia, endothelial dysfunction and hypertension. Women have a more beneficial traditional CVD risk profile (lower fasting plasma glucose, less atherogenic lipid profile) and a lower absolute risk for CVD than men. However, the relative risk for CVD associated with hyperglycaemia and dyslipidaemia is several-fold higher in women than in men. The reasons for the sex differences in CVD risk associated with metabolic abnormalities are unclear but could be related to differences in the mechanisms that cause hyperglycaemia and dyslipidaemia in men and women, which could influence the pathogenic processes involved in CVD. In the present paper, we review the influence of a person's sex on key aspects of metabolism involved in the cardiometabolic disease process, including insulin action on endogenous glucose production, tissue glucose disposal, and adipose tissue lipolysis, insulin secretion and insulin plasma clearance, postprandial glucose, fatty acid, and triglyceride kinetics, hepatic lipid metabolism and myocardial substrate use. We conclude that there are marked differences in many aspects of metabolism in men and women that are not all attributable to differences in the sex hormone milieu. The mechanisms responsible for these differences and the clinical implications of these observations are unclear and require further investigation.
      PubDate: 2020-05-01T00:00:00.000Z
      DOI: 10.1017/S0029665119001022
      Issue No: Vol. 79, No. 2 (2020)
       
  • n-3+fatty+acid+metabolism&rft.title=Proceedings+of+the+Nutrition+Society&rft.issn=0029-6651&rft.date=2020&rft.volume=79&rft.spage=219&rft.epage=224&rft.aulast=Childs&rft.aufirst=Caroline&rft.au=Caroline+E.+Childs&rft_id=info:doi/10.1017/S0029665119001071">Sex hormones and n-3 fatty acid metabolism
    • Authors: Caroline E. Childs
      Pages: 219 - 224
      Abstract: α-Linolenic acid (ALA) is an n-3 fatty acid found in plant-derived foods such as linseeds and linseed oil. Mammals can convert this essential fatty acid into longer-chain fatty acids including EPA, docosapentaenoic acid (DPA) and DHA. Women demonstrate greater increases in the EPA status after ALA supplementation than men, and a growing body of animal model research identifies mechanisms by which sex hormones such as oestrogen and progesterone interact with the synthesis of EPA and DHA. Alternatively, EPA, DPA and DHA can be consumed directly, with oily fish being a rich dietary source of these nutrients. However, current National Diet and Nutrition Data reveals a median oily fish intake of 0 g daily across all age ranges and in both sexes. As longer-chain n-3 fatty acids have a crucial role in fetal and neonatal brain development, advice to consume dietary ALA could prove to be a pragmatic and acceptable alternative to advice to consume fish during pregnancy, if benefits upon tissue composition and functional outcomes can be demonstrated. Further research is required to understand the effects of increasing dietary ALA during pregnancy, and will need to simultaneously address conflicts with current dietary advice to only eat ‘small amounts’ of vegetable oils during pregnancy. Improving our understanding of sex-specific differences in fatty acid metabolism and interactions with pregnancy has the potential to inform both personalised nutrition advice and public health policy.
      PubDate: 2020-05-01T00:00:00.000Z
      DOI: 10.1017/S0029665119001071
      Issue No: Vol. 79, No. 2 (2020)
       
  • Why interindividual variation in response to consumption of plant food
           bioactives matters for future personalised nutrition
    • Authors: Christine Morand; Baukje De Roos, Maria Teresa Garcia-Conesa, Eileen R. Gibney, Rikard Landberg, Claudine Manach, Dragan Milenkovic, Ana Rodriguez-Mateos, Tom Van de Wiele, Francisco Tomas-Barberan
      Pages: 225 - 235
      Abstract: Food phytochemicals are increasingly considered to play a key role in the cardiometabolic health effects of plant foods. However, the heterogeneity in responsiveness to their intake frequently observed in clinical trials can hinder the beneficial effects of these compounds in specific subpopulations. A range of factors, including genetic background, gut microbiota, age, sex and health status, could be involved in these interindividual variations; however, the current knowledge is limited and fragmented. The European network, European Cooperation in Science and Technology (COST)-POSITIVe, has analysed, in a systematic way, existing knowledge with the aim to better understand the factors responsible for the interindividual variation in response to the consumption of the major families of plant food bioactives, regarding their bioavailability and bioefficacy. If differences in bioavailability, likely reflecting differences in human subjects’ genetics or in gut microbiota composition and functionality, are believed to underpin much of the interindividual variability, the key molecular determinants or microbial species remain to be identified. The systematic analysis of published studies conducted to assess the interindividual variation in biomarkers of cardiometabolic risk suggested some factors (such as adiposity and health status) as involved in between-subject variation. However, the contribution of these factors is not demonstrated consistently across the different compounds and biological outcomes and would deserve further investigations. The findings of the network clearly highlight that the human subjects’ intervention studies published so far are not adequate to investigate the relevant determinants of the absorption/metabolism and biological responsiveness. They also emphasise the need for a new generation of intervention studies designed to capture this interindividual variation.
      PubDate: 2020-05-01T00:00:00.000Z
      DOI: 10.1017/S0029665120000014
      Issue No: Vol. 79, No. 2 (2020)
       
  • Personalised nutrition – phenotypic and genetic variation in
           response to dietary intervention
    • Authors: Eileen R. Gibney
      Pages: 236 - 245
      Abstract: Personalised nutrition allows individual differences in dietary, lifestyle, anthropometry, phenotype and/or genomic profile to be used to direct specific dietary advice. For personalised nutrition advice to be effective both sides need to be considered; firstly, that factors influencing variation in response to dietary intervention are identified and appropriate advice can be derived and secondly; that these are then used effectively in the provision of nutrition advice, resulting in a positive dietary and/or lifestyle behaviour change. There is considerable evidence demonstrating genetic and phenotypic influence on the biological response to the consumption of nutrients and bioactives. However, findings are often mixed, with studies often investigating at the level of a single nutrient/bioactive and/or a single genetic/phenotypic variation, meaning the derivation of specific advice at a dietary level in an individual/group of individuals can be complex. Similarly, the impact of using this information to derive personalised advice is also mixed, with some studies demonstrating no effectiveness and others showing a significant impact. The present paper will outline examples of phenotypic and genetic variation influencing response to nutritional interventions, and will consider how they could be used in the provision of personalised nutrition.
      PubDate: 2020-05-01T00:00:00.000Z
      DOI: 10.1017/S0029665119001137
      Issue No: Vol. 79, No. 2 (2020)
       
  • Future perspectives in addressing the global issue of vitamin D deficiency
    • Authors: M. M. Mendes; K. Charlton, S. Thakur, H. Ribeiro, S. A. Lanham-New
      Pages: 246 - 251
      Abstract: Vitamin D is a fundamentally critical nutrient that the human body requires to function properly. It plays an important role in musculoskeletal health due to its involvement in the regulation of calcium and phosphorus. Having a low level of vitamin D in the body may be detrimental for a wide range of health outcomes, including risk of osteoporotic and stress fractures, risk of CVD and some cancers, and lowering of the capability of the immune system. Vitamin D is an unusual nutrient; it is not a vitamin, in the true sense of the word but a pro-hormone. The main source of vitamin D is UV exposure, not dietary intake. Interestingly, there are two forms of vitamin D, vitamin D2 and vitamin D3, both of which are metabolised into 25-hydroxyvitamin D (25(OH)D) in the liver, the biomarker of vitamin D status. Vitamin D deficiency is a global public health problem, especially amongst older people and ethnic minority groups. The newest publication from the UK Government's Public Health England Department recommends that vitamin D intake should be 10 μg daily and this recommendation compares well (albeit lower) with other guidelines such as the Institute of Medicine recommendation of 15 μg for those aged 1–70 years and 20 μg for those 70 years or over. Few countries, however, have a specific vitamin D policy to prevent deficiency in populations. Finland leads the way, demonstrating impressive results in reducing population-level vitamin D deficiency through mandatory food fortification programmes. Collaboration between academia, government and industry, including countries from varying latitudes, is essential to identify long-term solutions to the global issue of vitamin D deficiency. This paper provides a narrative review of the evidence related to the role of vitamin D deficiency in health outcomes, outlines controversies regarding setting levels of adequacy, identifies the prevalence of vitamin D deficiency across the globe, and identifies population-level strategies adopted by countries to prevent vitamin D deficiency.
      PubDate: 2020-05-01T00:00:00.000Z
      DOI: 10.1017/S0029665119001538
      Issue No: Vol. 79, No. 2 (2020)
       
 
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