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Publisher: Science and Education Publishing   (Total: 72 journals)

American J. of Applied Mathematics and Statistics     Open Access  
American J. of Applied Psychology     Open Access  
American J. of Biomedical Research     Open Access   (Followers: 3)
American J. of Cancer Prevention     Open Access   (Followers: 3)
American J. of Civil Engineering and Architecture     Open Access   (Followers: 16)
American J. of Clinical Medicine Research     Open Access   (Followers: 5)
American J. of Educational Research     Open Access   (Followers: 21)
American J. of Electrical and Electronic Engineering     Open Access   (Followers: 10)
American J. of Energy Research     Open Access   (Followers: 6)
American J. of Environmental Protection     Open Access   (Followers: 3)
American J. of Epidemiology and Infectious Disease     Open Access  
American J. of Food and Nutrition     Open Access   (Followers: 1)
American J. of Food Science and Technology     Open Access   (Followers: 2)
American J. of Infectious Diseases and Microbiology     Open Access   (Followers: 13)
American J. of Information Systems     Open Access  
American J. of Materials Engineering and Technology     Open Access  
American J. of Materials Science and Engineering     Open Access  
American J. of Mathematical Analysis     Open Access  
American J. of Mechanical Engineering     Open Access  
American J. of Medical and Biological Research     Open Access   (Followers: 4)
American J. of Medical Case Reports     Open Access  
American J. of Medical Sciences and Medicine     Open Access  
American J. of Medicine Studies     Open Access  
American J. of Microbiological Research     Open Access  
American J. of Modeling and Optimization     Open Access  
American J. of Nanomaterials     Open Access  
American J. of Numerical Analysis     Open Access  
American J. of Pharmacological Sciences     Open Access   (Followers: 1)
American J. of Public Health Research     Open Access   (Followers: 12)
American J. of Rural Development     Open Access  
American J. of Sensor Technology     Open Access  
American J. of Sports Science and Medicine     Open Access  
American J. of Water Resources     Open Access  
American J. of Zoological Research     Open Access  
Applied Ecology and Environmental Sciences     Open Access   (Followers: 10)
Automatic Control and Information Sciences     Open Access  
Biomedical Science and Engineering     Open Access  
Chemical Engineering and Science     Open Access   (Followers: 2)
Intl. J. of Celiac Disease     Open Access   (Followers: 2)
Intl. J. of Dental Sciences and Research     Open Access  
Intl. J. of Econometrics and Financial Management     Open Access  
Intl. J. of Physics     Open Access  
Intl. Transaction of Electrical and Computer Engineers System     Open Access  
J. of Automation and Control     Open Access  
J. of Biomedical Engineering and Technology     Open Access  
J. of Business and Management Sciences     Open Access  
J. of Cancer Research and Treatment     Open Access  
J. of Computer Networks     Open Access  
J. of Computer Sciences and Applications     Open Access  
J. of Environment Pollution and Human Health     Open Access  
J. of Finance and Accounting     Open Access  
J. of Finance and Economics     Open Access   (Followers: 4)
J. of Food and Nutrition Research     Open Access  
J. of Food Security     Open Access  
J. of Geosciences and Geomatics     Open Access  
J. of Materials Physics and Chemistry     Open Access  
J. of Mathematical Sciences and Applications     Open Access  
J. of Optoelectronics Engineering     Open Access  
J. of Polymer and Biopolymer Physics Chemistry     Open Access  
Materials Science and Metallurgy Engineering     Open Access  
Nanoscience and Nanotechnology Research     Open Access  
Physics and Materials Chemistry     Open Access  
Research in Plant Sciences     Open Access  
Research in Psychology and Behavioral Sciences     Open Access  
Sustainable Energy     Open Access  
Turkish J. of Analysis and Number Theory     Open Access  
Wireless and Mobile Technologies     Open Access  
World J. of Agricultural Research     Open Access  
World J. of Analytical Chemistry     Open Access  
World J. of Chemical Education     Open Access  
World J. of Environmental Engineering     Open Access  
World J. of Organic Chemistry     Open Access  
Journal Cover American Journal of Pharmacological Sciences
   [3 followers]  Follow    
  This is an Open Access Journal Open Access journal
     ISSN (Print) 2327-6711 - ISSN (Online) 2327-672X
     Published by Science and Education Publishing Homepage  [72 journals]
  • Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery

    • Authors: Pratibha G. Kakadia; Barbara R. Conway
      Pages: 1 - 7
      Abstract: Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics. The ability to incorporate drugs into nanoparticles offers a new prototype in drug delivery thus realizing the dual goal of both controlled release and site-specific drug delivery. Drug delivery to the skin is widely used for local and systemic delivery and has potential to be improved by application of nanoparticulate formulations. If investigated appropriately, solid lipid nanoparticles may open new opportunities in therapy of complex diseases which is difficult to treat.
      PubDate: 2104-09-22
      Issue No: Vol. 2, No. 5A (2104)
       
  • Breaking the Skin Barrier: Current Advancement in Drug Delivery via Skin

    • Authors: YU-LIN CHOU; Yasser Shahzad, Madeeha Malik
      Pages: 0 - 0
      PubDate: 2014-09-20
      Issue No: Vol. 2, No. 5A (2014)
       
  • Optimization and Permeation Study of Novel Topically Applied Antilipemic
           Lotion Using Central Composite Design

    • Authors: Asma Aslam; Rummana Riaz, Yasser Shahzad, Atif Akber, Ikram Ullah Khan, Syed Nisar Hussain Shah
      Pages: 8 - 14
      Abstract: In this study, synergistic effect of penetration enhancers, namely propylene glycol (PG) and sodium lauryl Sulphate (SLS) on transdermal absorption of 2-Methyl-2-phenoxy-propionic acid (MPA) was evaluated with aid of response surface methodology (RSM) based formulations. The prepared formulations were characterised and subsequently subjected to diffusion cell experiments through a well-established skin mimic, namely silicone membrane. Data obtained were statistically analysed using analysis of variance (ANOVA) and regression analysis. Comparisons were made with the control and among different parameters of formulations. PG (X1) and SLS (X2) were selected as independent variables, whereas the cumulative amount of MPA were used to calculate dependent permeation kinetic parameters like lag time (tlag) and enhancement ratios (ER). It was observed from the results that PG had a significant effect on MPA absorption from the lotion followed by SLS and their combination showed a significant enhancement (p< 0.05) in the flux from the formulated lotions compared to the control. The highest enhancement ratio (ER=8.6) was observed for L4. Contour plots were then drawn to depict the relationship between independent and response variables. Among the formulations, L4 showed highest flux value with less lag time (12.2 min), thereby, identified and selected as an optimized formulation. In conclusion, the combination of PG and SLS can be successfully utilized as permeation enhancers for transdermal drug delivery of MPA with minimal side effects.
      PubDate: 2014-09-30
      Issue No: Vol. 2, No. 5A (2014)
       
 
 
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