American Journal of Infectious Diseases and Microbiology
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Open Access journal
ISSN (Print) 2328-4056 - ISSN (Online) 2328-4064
Published by Science and Education Publishing [72 journals]
- Occurrence of a Cholera Outbreak in Central India
Authors: Meena Mishra; Arvind Kurhade, Yagnesh Thakar, Geeta Kurhade, Angel Justiz Vaillant, Sudhir Lakhdive, Tejaswini H Joshi, Sehlule Vuma
Pages: 141 - 143
Abstract: The aim of this research was to carry out a bacteriological study of Vibrio cholerae in Central India. Cholera is an important public health problem in India and it continues to be a major concern as it is an important cause of morbidity mortality. A total of 44 strains of V. cholerae were isolated from 150 stool samples received from patients with acute diarrhea. All samples were plated onto different bacteriological media. Biotyping was performed as per the standard procedures. Confirmation of the strains was done by seroagglutination using Polyvalent O1, monospecific Ogawa and Inaba antisera. Antibiotic susceptibility testing was performed by Kirby Bauer's disk diffusion method. The majority of the isolates belonged to type 27 (70.45%, i.e. 31 isolates). All Isolates were susceptible to tetracycline, norfloxacin and were relatively susceptible to gentamicin (95%) and chloramphenicol (95%). Continued monitoring, surveillance of all outbreaks and notification to relevant authorities are of utmost importance in the fight against cholera. In addition, the molecular subtyping was essential to improve the tracing of the sources of the outbreak.
Issue No: Vol. 3, No. 5 (2015)
- Culture Negative Abscesses at Multiple Sites: A Diagnostic and Management
Dilemma in a District Hospital
Authors: Cynthia Sandanamsamy; Lai Nai Kiat Sean, Chan Weng Kit, Naganathan, Ganesh Kasinathan
Pages: 144 - 146
Abstract: Background: Culture negative abscesses at multiple sites are a common phenomenon. It is an important source of sepsis and septic shock in many developed and developing countries worldwide. Case Presentation: This case describes a 42 year-old Malay gentleman who presented to us with high grade fever associated with cough, foul-smelling sputum and pleurisy. He has underlying chronic Type 2 Diabetes Mellitus. He works as a rubber tapper, a smoker with a 40 pack years history, and a teetotaler. On physical examination, he had notable pyrexia with stable vital signs. He was septic looking and had obvious rigors. His dental hygiene was poor with multiple caries. Lungs were clear on auscultation. Examination of the abdomen revealed tender hepatosplenomegaly. Chest radiograph showed multiple cavitating lesions suggestive of lung abscesses. A subsequent Contrast Enhanced Computed Tomography (CECT) of the thorax, abdomen and pelvis revealed multiple lung, liver, splenic and adrenal abscesses of different sizes. A 2D transthoracic echocardiogram did not reveal any vegetation. Tuberculosis and viral screening were negative. His melioidosis serology titer was not significant. Multiple sets of blood, sputum and urine cultures did not grow any organism. He was treated for culture negative abscesses with a six week course of parenteral third generation cephalosporin antibiotics and metronidazole. Repeated imaging showed significant improvement of all abscesses and he responded well clinically. Conclusion: Effective and early management of culture negative abscesses with broad spectrum antibiotics is vital in reducing overall mortality and morbidity.
Issue No: Vol. 3, No. 5 (2015)