American Journal of Infectious Diseases and Microbiology
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  This is an Open Access Journal Open Access journal
     ISSN (Print) 2328-4056 - ISSN (Online) 2328-4064
     Published by Science and Education Publishing Homepage  [19 journals]
  • Oral Tuberculosis: An Acid Fast Negative Case Report

    • Authors: Mehdi Nasr Isfahani; Parichehr Ghalayani, Fahimeh Pakravan
      Pages: 45 - 47
      Abstract: We report a rare case of tuberculosis of oral cavity in a 3.5 year-old male who was referred to oral medicine department with a chief complaint of a painless lesion in the oral cavity. Incisional biopsy from the lesion margin depicted histological features of necrotizing granulomatous lesion. Ziehl-Neelsen staining for acid fast bacilli, interestingly, was negative.
      PubDate: 2014-06-11
      Issue No: Vol. 2, No. 3 (2014)
  • Pulmonary Tuberculosis Disseminating and Presenting as Bilateral
           Hydronephrosis and Renal Abscess: a Potential Threat in the Era of
           Multi-Drug Resistant Tuberculosis MDR-TB

    • Authors: K V Ramana
      Pages: 48 - 50
      Abstract: Mycobacterium tuberculosis, the causative agent of tuberculosis was discovered by Robert Koch in 1882. It has been observed that 30% of the world population harbours Mycobacterium tuberculosis. Spread of Human immunodeficiency virus (HIV) infection, malignancies, globalization and malnutrition are some of the major contributing factors for increase in the global burden of tuberculosis (pulmonary and extra-pulmonary TB). Dissemination/spread of tubercle bacilli from the lungs to other organs of the body either through blood or lymphatic circulation results in extra-pulmonary tuberculosis. Immunodeficiency, either due to HIV infection or malignancies, malnutrition and inadequate treatment for pulmonary TB may be considered as some of the predisposing factors for disseminated/miliary TB. It has also been noted that most cases of extra-pulmonary TB are diagnosed accidentally and after a long period of time (months to years) since recovering from pulmonary TB. In the era of Multi-drug resistant tuberculosis (MDR-TB), extremely drug resistant tuberculosis (XDR-TB) and increase in the incidences of disseminated/extra-pulmonary tuberculosis poses a challenge to the medical personnel. Among the extra-pulmonary cases of tuberculosis genitourinary tuberculosis (GUTB) appears to be most frequent as evidenced by the available literature.
      PubDate: 2014-07-01
      Issue No: Vol. 2, No. 3 (2014)
  • Large Intestine Infarction due to Mucormycosis Complicated with Acute
           Myeloid Leukemia. Case Report

    • Authors: Motoharu Shibusawa; Hiroko Hidai, Sayuri Motomura, Yuuji Itou, Hisashi Tsutsumi
      Pages: 51 - 54
      Abstract: Mucormycosis is known to be fatal, and the diagnosis is difficult to be made. Gastrointestinal mucormycosis is rarely complicated with gastrointestinal infarction. We report a rare case of mucormycosis complicated with large intestine infarction. An 82-year-old man was admitted to our hospital, because of blastosis. A diagnosis of acute myeloid leukemia prior myelodysplastic syndrome was made. On the twentieth day of admission, bleeding developed in the airway secondary to thrombocytopenia and disseminated intravascular coagulation. He died due to respiratory failure and autopsy was carried out. The novel finding of the autopsy was large intestine infarction due to mucormycosis, although the clinical course did not show features suggesting gastrointestinal mucormycosis. A diagnosis of mucormycosis was made by autopsy. In the patients with risk factors including hematologic malignancies, we should pay attention to gastrointestinal mucormycosis.
      PubDate: 2014-07-07
      Issue No: Vol. 2, No. 3 (2014)
  • Relative Deprivation, Sexually Transmitted Diseases and HIV and AIDS
           Mortality: A Multilevel Analysis

    • Authors: Augustine J. Kposowa
      Pages: 55 - 62
      Abstract: Objectives: Previous studies on the covariates of sexually transmitted diseases have concentrated on absolute deprivation, often measured by poverty. The aim of this study was to examine the association between relative deprivation (income inequality) and sexually transmitted diseases, and HIV and AIDS mortality. Method : Ecological data based on 3080 counties were obtained from the Area Resource File. State level data on the 50 states and the District of Columbia were derived from the Statistical Abstract of the United States. Multilevel generalized linear models were fitted to the data. Results: State level relative deprivation (measured as the Gini coefficient of income inequality) was strongly and significantly associated with both sexually transmitted diseases (b=12.96, t=4.27, p=.000), and HIV and AIDS mortality (b=20.41, t=5.58, p=.000). Absolute deprivation (poverty) was also associated with sexually transmitted diseases, but the association was not as strong as that of relative deprivation. Furthermore, poverty was not significantly associated with HIV and AIDS mortality at the county level. Conclusion: It was concluded that to reduce sexually transmitted diseases and HIV/AIDS, attention should be placed on combating economic inequality and poverty. One tack is to reduce social marginalization of segments of the population.
      PubDate: 2014-07-16
      Issue No: Vol. 2, No. 3 (2014)
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