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Publisher: Science and Education Publishing   (Total: 72 journals)

American J. of Applied Mathematics and Statistics     Open Access   (Followers: 2)
American J. of Applied Psychology     Open Access   (Followers: 11)
American J. of Biomedical Research     Open Access   (Followers: 3)
American J. of Cancer Prevention     Open Access   (Followers: 7)
American J. of Civil Engineering and Architecture     Open Access   (Followers: 21)
American J. of Clinical Medicine Research     Open Access   (Followers: 6)
American J. of Educational Research     Open Access   (Followers: 36)
American J. of Electrical and Electronic Engineering     Open Access   (Followers: 11)
American J. of Energy Research     Open Access   (Followers: 7)
American J. of Environmental Protection     Open Access   (Followers: 5)
American J. of Epidemiology and Infectious Disease     Open Access   (Followers: 3)
American J. of Food and Nutrition     Open Access   (Followers: 5)
American J. of Food Science and Technology     Open Access   (Followers: 3)
American J. of Infectious Diseases and Microbiology     Open Access   (Followers: 14)
American J. of Information Systems     Open Access   (Followers: 2)
American J. of Materials Engineering and Technology     Open Access  
American J. of Materials Science and Engineering     Open Access   (Followers: 1)
American J. of Mathematical Analysis     Open Access  
American J. of Mechanical Engineering     Open Access   (Followers: 1)
American J. of Medical and Biological Research     Open Access   (Followers: 3)
American J. of Medical Case Reports     Open Access  
American J. of Medical Sciences and Medicine     Open Access  
American J. of Medicine Studies     Open Access  
American J. of Microbiological Research     Open Access  
American J. of Modeling and Optimization     Open Access   (Followers: 1)
American J. of Nanomaterials     Open Access  
American J. of Numerical Analysis     Open Access  
American J. of Pharmacological Sciences     Open Access   (Followers: 1)
American J. of Public Health Research     Open Access   (Followers: 15)
American J. of Rural Development     Open Access   (Followers: 1)
American J. of Sensor Technology     Open Access   (Followers: 1)
American J. of Sports Science and Medicine     Open Access   (Followers: 5)
American J. of Water Resources     Open Access   (Followers: 1)
American J. of Zoological Research     Open Access  
Applied Ecology and Environmental Sciences     Open Access   (Followers: 13)
Automatic Control and Information Sciences     Open Access  
Biomedical Science and Engineering     Open Access   (Followers: 1)
Chemical Engineering and Science     Open Access   (Followers: 3)
Intl. J. of Celiac Disease     Open Access   (Followers: 2)
Intl. J. of Dental Sciences and Research     Open Access  
Intl. J. of Econometrics and Financial Management     Open Access  
Intl. J. of Physics     Open Access  
Intl. Transaction of Electrical and Computer Engineers System     Open Access  
J. of Automation and Control     Open Access   (Followers: 1)
J. of Biomedical Engineering and Technology     Open Access  
J. of Business and Management Sciences     Open Access  
J. of Cancer Research and Treatment     Open Access   (Followers: 1)
J. of Computer Networks     Open Access  
J. of Computer Sciences and Applications     Open Access  
J. of Environment Pollution and Human Health     Open Access   (Followers: 1)
J. of Finance and Accounting     Open Access  
J. of Finance and Economics     Open Access   (Followers: 6)
J. of Food and Nutrition Research     Open Access   (SJR: 0.344, h-index: 11)
J. of Food Security     Open Access  
J. of Geosciences and Geomatics     Open Access  
J. of Materials Physics and Chemistry     Open Access  
J. of Mathematical Sciences and Applications     Open Access  
J. of Optoelectronics Engineering     Open Access  
J. of Polymer and Biopolymer Physics Chemistry     Open Access   (Followers: 1)
Materials Science and Metallurgy Engineering     Open Access   (Followers: 1)
Nanoscience and Nanotechnology Research     Open Access   (Followers: 1)
Physics and Materials Chemistry     Open Access  
Research in Plant Sciences     Open Access  
Research in Psychology and Behavioral Sciences     Open Access  
Sustainable Energy     Open Access  
Turkish J. of Analysis and Number Theory     Open Access   (Followers: 1)
Wireless and Mobile Technologies     Open Access  
World J. of Agricultural Research     Open Access   (Followers: 1)
World J. of Analytical Chemistry     Open Access  
World J. of Chemical Education     Open Access   (Followers: 1)
World J. of Environmental Engineering     Open Access   (Followers: 1)
World J. of Organic Chemistry     Open Access  
Journal Cover   American Journal of Clinical Medicine Research
  [6 followers]  Follow
    
  This is an Open Access Journal Open Access journal
   ISSN (Print) 2328-4005 - ISSN (Online) 2328-403X
   Published by Science and Education Publishing Homepage  [72 journals]
  • The Effect of a Multi-strain Probiotic on the Symptoms and Small
           Intestinal Bacterial Overgrowth in Constipation-predominant Irritable
           Bowel Syndrome: A Randomized, Simple-blind, Placebo-controlled Trial

    • Authors: Ivashkin V; Drapkina O, Poluektova Ye, Kuchumova S, Sheptulin A, Shifrin O.
      Pages: 18 - 23
      Abstract: Background and aim: the qualitative and quantitative difference in the intestinal microbiota between irritable bowel syndrome (IBS) patients and healthy volunteers doesn't raise doubts. Small intestinal bacterial overgrowth(SIBO), reported in 9-35% patients with constipation-predominant of irritable bowel syndrome (IBS-C), is involved in the pathogenesis IBS. Elimination of SIBO can lead to improvement of clinical symptoms. The aim of this study was to assess the efficacy of a bifido- and lactobacillis-containing probiotic Florasan-D on the eradicating SIBO and on the severity of clinical symptoms in patients with IBS-C. Methods: this randomized (1 : 1), simple-blinded, placebo-controlled investigation conducted at one centre in Russia.33 patients with IBS-C (clinical type was determined according to ROME III criteria) were randomized to receive a multi-strainprobiotic Florasan-D containing Bifidobacteriumbifidum, Bifidobacteriumlongum, Bifidobacteriuminfantis, Lactobacillus rhamnosus or placebo for 4 weeks: 16 and 17 persons respectively. The intensity of abdominal pain and bloating was estimated by a visual analogue scale (VAS), stool consistency – by a Bristol stool form scale before and after the intervention. Quality of life was assessed by the Short Form-36 questionnaire (SF-36). All subjects were analysed by lactulose hydrogen breath test with using Gastro+ Gastrolyzer (Bedfont, UK) to determine SIBO. Results: patients treated with multi-strainprobiotic Florasan-D reported a reduction in the severity of clinical symptoms: abdominal pain decreased from 4 to 2 point (р=0,003), stool frequency – from 3 to 7 per week (р=0,001) and stoolconsistency – from type 2 to type 3 by a Bristol stool form scale (р=0,001); SIBO was found in 56,3% patients before treatment and no patients had this syndrome after therapy. Patients treated with placebo reported a reduction the severity of abdominal pain only (р=0,028). SIBO in these patients before treatment was revealed in 52,9% and remained in all patients after it. Conclusions: multi-strainprobiotic Florasan-D is significantly more effective than placebo for reduction of clinical symptoms and SIBO elimination in IBS-C patients.
      PubDate: 2015-04-07
      Issue No: Vol. 3, No. 2 (2015)
       
 
 
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