Publisher: Project MUSE   (Total: 295 journals)

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Showing 201 - 295 of 295 Journals sorted alphabetically
Philippine Studies     Full-text available via subscription   (Followers: 2, SJR: 0.18, CiteScore: 0)
philoSOPHIA     Full-text available via subscription   (Followers: 4)
Philosophy and Literature     Full-text available via subscription   (Followers: 25, SJR: 0.13, CiteScore: 0)
Philosophy East and West     Full-text available via subscription   (Followers: 11, SJR: 0.249, CiteScore: 0)
Philosophy, Psychiatry, & Psychology     Full-text available via subscription   (Followers: 6, SJR: 0.183, CiteScore: 0)
Ploughshares     Full-text available via subscription   (Followers: 2, SJR: 0.1, CiteScore: 0)
Population Review     Full-text available via subscription   (Followers: 1, SJR: 0.123, CiteScore: 0)
portal: Libraries and the Academy     Full-text available via subscription   (Followers: 224, SJR: 1.182, CiteScore: 1)
Postmodern Culture     Full-text available via subscription   (Followers: 11, SJR: 0.143, CiteScore: 0)
Progress in Community Health Partnerships: Research, Education, and Action     Full-text available via subscription   (Followers: 3, SJR: 0.427, CiteScore: 1)
Pushkin Review     Full-text available via subscription  
Quaker History     Full-text available via subscription   (Followers: 5)
Race/Ethnicity : Multidisciplinary Global Perspectives     Full-text available via subscription   (Followers: 8)
Red Cedar Review     Full-text available via subscription   (Followers: 1, SJR: 0.101, CiteScore: 0)
Region : Regional Studies of Russia, Eastern Europe, and Central Asia     Full-text available via subscription   (Followers: 11, SJR: 0.17, CiteScore: 0)
Register of the Kentucky Historical Society     Full-text available via subscription   (Followers: 4)
Restoration: Studies in English Literary Culture, 1660-1700     Full-text available via subscription   (Followers: 7)
Review of Higher Education     Full-text available via subscription   (Followers: 23, SJR: 1.601, CiteScore: 2)
Review of Japanese Culture and Society     Full-text available via subscription   (Followers: 3)
Reviews in American History     Full-text available via subscription   (Followers: 21, SJR: 0.101, CiteScore: 0)
Revista de Estudios Hispánicos     Full-text available via subscription   (Followers: 6)
Revista Hispánica Moderna     Full-text available via subscription   (Followers: 6)
Rhetoric & Public Affairs     Full-text available via subscription   (Followers: 10, SJR: 0.556, CiteScore: 1)
River Teeth: A J. of Nonfiction Narrative     Full-text available via subscription  
Rocky Mountain Review     Full-text available via subscription   (Followers: 1)
Romance Notes     Full-text available via subscription   (Followers: 2, SJR: 0.107, CiteScore: 0)
RSF : The Russell Sage Foundation J. of the Social Sciences     Open Access   (Followers: 1)
SAIS Review     Full-text available via subscription   (Followers: 2)
Scottish Literary Review     Full-text available via subscription   (Followers: 1, SJR: 0.101, CiteScore: 0)
SEL Studies in English Literature 1500-1900     Full-text available via subscription   (Followers: 11, SJR: 0.131, CiteScore: 0)
Seoul J. of Korean Studies     Full-text available via subscription   (Followers: 6, SJR: 0.102, CiteScore: 0)
Serbian Studies: J. of the North American Society for Serbian Studies     Full-text available via subscription   (Followers: 2)
Sewanee Review     Full-text available via subscription   (Followers: 1, SJR: 0.1, CiteScore: 0)
Shakespeare Bulletin     Full-text available via subscription   (Followers: 13)
Shakespeare Quarterly     Full-text available via subscription   (Followers: 26, SJR: 0.111, CiteScore: 0)
Shofar: An Interdisciplinary J. of Jewish Studies     Full-text available via subscription   (Followers: 15, SJR: 0.103, CiteScore: 0)
Sign Language Studies     Full-text available via subscription   (Followers: 7, SJR: 0.554, CiteScore: 1)
Sirena: poesia, arte y critica     Full-text available via subscription   (Followers: 2)
Social Research : An Intl. Quarterly     Full-text available via subscription   (Followers: 5, SJR: 0.19, CiteScore: 0)
Sojourn: J. of Social Issues in Southeast Asia     Full-text available via subscription   (Followers: 11, SJR: 0.294, CiteScore: 0)
South Central Review     Full-text available via subscription   (SJR: 0.105, CiteScore: 0)
Southeast Asian Affairs     Full-text available via subscription   (Followers: 6)
Southeastern Geographer     Full-text available via subscription   (SJR: 0.258, CiteScore: 0)
Southern Cultures     Full-text available via subscription   (SJR: 0.106, CiteScore: 0)
Southern Literary J.     Full-text available via subscription   (Followers: 4)
Southern Quarterly     Full-text available via subscription   (Followers: 2)
Southern Review     Full-text available via subscription   (Followers: 2)
Southwestern Historical Quarterly     Full-text available via subscription   (Followers: 5, SJR: 0.116, CiteScore: 0)
Spiritus: A J. of Christian Spirituality     Full-text available via subscription   (Followers: 9, SJR: 0.125, CiteScore: 0)
Studies in American Fiction     Full-text available via subscription   (Followers: 3, SJR: 0.101, CiteScore: 0)
Studies in Bibliography     Full-text available via subscription   (Followers: 9)
Studies in Eighteenth Century Culture     Full-text available via subscription   (Followers: 26, SJR: 0.101, CiteScore: 0)
Studies in Latin American Popular Culture     Full-text available via subscription   (Followers: 7, SJR: 0.102, CiteScore: 0)
Studies in Philology     Full-text available via subscription   (Followers: 4, SJR: 0.101, CiteScore: 0)
Studies in the Age of Chaucer     Full-text available via subscription   (Followers: 3, SJR: 0.24, CiteScore: 1)
Studies in the Literary Imagination     Full-text available via subscription   (Followers: 11, SJR: 0.1, CiteScore: 0)
Studies in the Novel     Full-text available via subscription   (Followers: 10, SJR: 0.101, CiteScore: 0)
Syllecta Classica     Full-text available via subscription   (Followers: 3)
Tampa Review     Full-text available via subscription  
Technology and Culture     Full-text available via subscription   (Followers: 25, SJR: 0.284, CiteScore: 0)
Tenso     Full-text available via subscription   (Followers: 2)
Texas Studies in Literature and Language     Full-text available via subscription   (Followers: 2)
The Comparatist     Full-text available via subscription   (Followers: 4)
The Hopkins Review     Full-text available via subscription   (Followers: 2)
The Jurist : Studies in Church Law and Ministry     Full-text available via subscription   (Followers: 1)
The Lion and the Unicorn     Full-text available via subscription   (Followers: 14, SJR: 0.123, CiteScore: 0)
The Massachusetts Review     Full-text available via subscription   (Followers: 2, SJR: 0.1, CiteScore: 0)
The Moving Image     Full-text available via subscription   (Followers: 4, SJR: 0.1, CiteScore: 0)
The Scriblerian and the Kit-Cats     Full-text available via subscription  
The Tocqueville Review/La revue Tocqueville     Full-text available via subscription   (Followers: 3, SJR: 0.169, CiteScore: 0)
The Velvet Light Trap     Full-text available via subscription   (Followers: 7)
Theatre History Studies     Full-text available via subscription   (Followers: 6, SJR: 0.101, CiteScore: 0)
Theatre J.     Full-text available via subscription   (Followers: 19, SJR: 0.156, CiteScore: 0)
Theatre Notebook     Full-text available via subscription   (Followers: 5)
Theatre Symposium     Full-text available via subscription   (Followers: 5)
Theatre Topics     Full-text available via subscription   (Followers: 12)
Theory & Event     Full-text available via subscription   (Followers: 12)
Tolkien Studies     Full-text available via subscription   (Followers: 10)
Toronto J. of Theology     Full-text available via subscription   (Followers: 7, SJR: 0.105, CiteScore: 0)
Traditio     Full-text available via subscription   (Followers: 2, SJR: 0.111, CiteScore: 0)
Transactions of the American Philological Association     Full-text available via subscription   (Followers: 5, SJR: 0.338, CiteScore: 0)
Transformation: Critical Perspectives on Southern Africa     Full-text available via subscription   (Followers: 3)
Tulsa Studies in Women's Literature     Full-text available via subscription   (Followers: 7, SJR: 0.101, CiteScore: 0)
U.S. Catholic Historian     Full-text available via subscription   (Followers: 2)
U.S.-Japan Women's J.     Full-text available via subscription   (Followers: 1)
Victorian Periodicals Review     Full-text available via subscription   (Followers: 14, SJR: 0.338, CiteScore: 0)
Victorian Poetry     Full-text available via subscription   (Followers: 10, SJR: 0.166, CiteScore: 0)
Wallace Stevens J.     Full-text available via subscription   (SJR: 0.1, CiteScore: 0)
West Virginia History: A J. of Regional Studies     Full-text available via subscription   (Followers: 1)
Wicazo Sa Review     Full-text available via subscription   (Followers: 1)
William Carlos Williams Review     Full-text available via subscription   (Followers: 3)
Women in French Studies     Full-text available via subscription   (Followers: 3)
WSQ: Women's Studies Quarterly     Full-text available via subscription   (Followers: 11)
Yearbook of Comparative Literature     Full-text available via subscription   (Followers: 17)
Yearbook of the Association of Pacific Coast Geographers     Full-text available via subscription   (Followers: 2)

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Similar Journals
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Serbian Studies: Journal of the North American Society for Serbian Studies
Number of Followers: 2  
 
  Full-text available via subscription Subscription journal
ISSN (Print) 0742-3330 - ISSN (Online) 1941-9511
Published by Project MUSE Homepage  [295 journals]
  • A Note from the Editors
    • Abstract: This is the second volume of Serbian Studies dedicated to the life, experience, and contributions—practical and creative—of the Jewish people in Serbia. Their presence on the Balkan Peninsula dates back to Roman times. While the exact time of their arrival in Serbia is not certain, there is firm evidence of their presence during the Middle Ages. Moreover, a significant increase in Jewish population and settlements occurred in the fifteenth century following their expulsion from Spain and Portugal. The history of both Sephardic and Ashkenazi Jews in Serbia is lengthy, and their life within Serbian society, especially during the nineteenth and twentieth centuries, is well documented. The Jewish ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • Life of the Jewish Community in the Serbian City of Šabac
    • Abstract: This article examines the brief history of a Jewish community in an important but provincial city in Serbia—Šabac. In order to accomplish that task, the author consulted a variety of archival materials, collected the last surviving oral traditions, and conducted fieldwork. It is the author’s hope that this article will provide insight into the lives of the Jewish citizens of Šabac as well as provide materials to compare these lives with the lives of individuals from Jewish communities in other provincial Serbian towns. The city of Šabac is located on the right bank of the Sava river, about 80 kilometers due west of Belgrade. Until the end of World War I, it rested on the border of the ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • David Albala: The Forging of a Double Loyalty
    • Abstract: David Albala (b. Belgrade 1886; d. Washington 1942) was an outstanding representative of the Serbian and Yugoslav Jewish community. His parents, Lea Malamed and Avram Kovu, were Sephardim who lived for a while in Rumania (Craiowa and Turnu Severin) and then in Serbia (Belgrade). David was born in Belgrade and was one of seven siblings in the fairly poor Kovu family. When both parents died, the children were transferred to the care of seven different families.1 Five-year-old David was adopted by his maternal aunt and her husband Isak Albala, whose last name he assumed and kept to the end of his life. The Albala family lived in Dorćol, the Sephardic quarter of Belgrade, where he completed his secondary education in ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • Ana Šomlo: A Live Bridge Between Serbian and Jewish Culture
    • Abstract: The life and work of Ana Šomlo (1935–) is a unique blend of two cultures— Serbian and Jewish—tempered by love. It is a fine illustration of the harmonious Serbian and Jewish coexistence in times of peace and the shared persecution and suffering inflicted by the same enemies and invaders in times of war. Ana’s mother, Budimka, the daughter of a Serbian tailor from Vršac, married Miroslav Šomlo, a Jew, born in Budapest. His parents, Solomon Štraser and Gisela Vajs, had moved to Hungary from Slovakia in the 1870s. A veterinarian, Solomon worked at the Budapest railway station’s department regulating kosher meat transportation. Following World War I, he had to change his last name to the Hungarian ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • Oskar Davičo and Danilo Kiš: Two Serbian-Jewish Writers and Their
           Approach to Jewish Themes in Modern Serbian Literature
    • Abstract: After the Second World War, Serbian literature passed through many phases and changes: from socialist realism to realism, from realism to modernism, and from modernism to what was called “a different kind of realistic political literature.”1 This final phase namely involves a profusion of novels which deal with the year 1948, the Cominform, the Yugoslav Gulag on the Adriatic island of Goli Otok, and the nationalistic themes which are predominant in the writings about the civil war, and the killing of the civilian population of what was then Yugoslavia. Throughout its many changes and styles, one theme has remained constant: ethnicity. Some of the best-known Serbian writers are recognized by the ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • Rivers in World Cultures and Languages
    • Abstract: From deep in our past, rivers have meant refreshment, cleansing, sustenance, transportation to and communication with places far and near. Rivers have brought melted snow from mountain heights to valley fields, relief to thirsting lips and revival to parched crops. The Russians recognize the life-bearing and life-sustaining force of water in referring to their mightiest river as, e.g., matushka Volga, “Mother Volga.” In some cultures, rivers bear away the dead, as the rivers Styx and Lethe of the Greek literary tradition transport the souls of the dead to the underworld and wipe away memory, and, as on the banks of the Ganges in India, rivers embrace the physical cremated remains of those who have died. ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • Dona’s Set of Dishes (Cadik Danon’s Story)
    • Abstract: Our families slowly disappeared from Belgrade. Children scattered about the world and the old died faster, so that Olga and I inherited a “new” piece of furniture more frequently. It was the hardest when we were forced to empty the apartment and sell out our furniture. Along with the pieces of estranged items, our memories, the closest and dearest, disappeared too. It became painful to touch the objects that they had used for decades. The more valuable, well-preserved furniture, we somehow integrated with our own in our large apartment, so that in the same room, next to each other, were lined clocks from different epochs, strangely, all working. Upon the inherited chests of drawers and tables, besides the ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • Words Fly, the Written Word Stays…
    • Abstract: I, the writer of these lines, am the product of the end of the third decade of the twentieth century and, here I am, still alive at the beginning of the new century and millennium… … I have had a “turbulent past.” Several times I started life, not over but a new life altogether. I changed my identity, lied to defend myself from evil, in an effort to avoid, at least for a short while, a fatal destiny. I got to know the character and nature of the people whom I loved and who loved me, and also those for whom I was an unpleasant burden. I walked the right paths but also the wrong ones, the primrose paths, in search of fairness… So what else is left for me, here and now' Just memory and forgetting. ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • A Note on Ženi Lebl
    • Abstract: Ženi Lebl was born in Aleksinac, Serbia on 20 June 1927. In 1933 the family moved to Belgrade, where she completed elementary school and junior high school. At the beginning of WWII, when her mother and grandmother were taken to a concentration camp equipped with gas chambers, Lebl fled to the city of Niš. She changed her name to Jovanka Lazić and came to live with Jelena Glavaski. When they engaged in the printing of Partisan1 literature, they were imprisoned. Jelena was executed and the teenage Lebl was sent to a labor camp in Germany and then to Berlin, into the hands of the Gestapo. In 1945 she was liberated and subsequently returned to Belgrade where she continued her education. Following graduation ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • Leon Kojen: “Son of the Serbian Nation”
    • Abstract: Artists’ relationships with contemporary social movements, government institutions, or national ideas shape their thematic repertoire and determined exhibition policies and public engagement. This was particularly evident during turbulent political times and in regions that experienced multinational conflict. The activities of Leon Kojen (1859–1934) provide a clear example of the relationship of the artist to society and the State. Kojen was a well-known Jewish painter from Serbia who in his work incorporated Jewish themes, while also expressing a commitment to the idea of the Serbian state. In scholarship to date, this has not been addressed even though it is of particular importance to better understand ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • Synagogues in Recent Serbian Architecture
    • Abstract: Synagogues were, and still are, a strong spiritual center and the focus of the religious life of Jewish communities. Their primary function was to provide a place for the faithful and a space for education and other various functions. In the more recent history of Serbian architecture, synagogue buildings hold a distinguished position as important religious and cultural complexes, and for that reason they are the subject of this study. In the territory of modern Serbia, a few dozens of these structures were originally built to serve the religious function of the Sephardic or Ashkenazi rites. Most synagogues were constructed in the region of Vojvodina, especially in Banat and Bačka; there are a few ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • Josif Najman: Belgrade Architect Between the Two Wars
    • Abstract: Josif Najman (5 May 1894–1 January 1951) was a Serbian architect of Jewish descent belonging to a generation of prolific designers in the period between the two World Wars in the Kingdom of Serbs, Croats, and Slovenes (Kingdom of Yugoslavia from 1929).1 His professional career was relatively brief, beginning in 1925 when he decided to enter the domestic architectural scene, and lasting until early in 1951 when he suddenly passed away. By that time, he had completed over forty state-sponsored and private projects. He also led many projects which were especially significant industrial complexes, thus initiating a new chapter in Serbian architecture. Establishing a specific and recognizable signature style, he ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • The Construction of the House of the Jewish Church-School Community in
           Belgrade and the Process of Jewish Emancipation
    • Abstract: Through the construction of the House of the Jewish Church-School Community in Belgrade,1 based on the project by architect Samuel Sumbul (1887– 1947), the process of the emancipation of the Belgrade Jewry in the Kingdom of Serbs, Croats, and Slovenes (SCS) (1918–29) was complete (Figure 1). This representative public edifice became a functional entity with the Bet Jisrael synagogue, to which it was physically connected. These spaces of Jewish religious and creedal practices, educational activities, social and communal manifestations, and political events were united as meeting places of representatives of the Jewish community and the state at the time. The House of the Jewish Church-School Community, being ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • The Last Synagogues in Vojvodina: Synagogues of Subotica and Novi Sad
    • Abstract: Due to the geopolitical situation when Vojvodina was a part of the former Austro-Hungarian monarchy, the existence of synagogue architecture1 there was based on the fact that during the nineteenth and early twentieth centuries the Jewish community in this region experienced emancipation in terms of equality with other ethnic, religious, and national minorities. This is supported by the fact that as of 1867 the Jewish people in Vojvodina under the Austro-Hungarian Empire became equal with the rest of the population with respect to their education and professions. At the end of 1895 a law came into force according to which Judaism was given equality with all other religions.2 The Jewish people were rarely able to ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • Šabac i Jevreji u susretu ed. by Miloš Jevtić, and: People with Big
           Heart: Friendship without Borders ed. by Miloš Jevtić (review)
    • Abstract: These two books, the latter a translation of the former, compile a beautiful tribute to the people of Šabac, throughout history and into the Second World War, who have celebrated a history of openness and friendship, as the English title suggests. In the opening words of this book entitled “Reč unapred” (translated “Forward”), Miodrag-Mile Nikolić offers homage to his maternal grandfather, Dr. Miodrag-Mile Petrović, a former officer of the Serbian Royal Army, doctor of law, diplomat, and a city mayor. He performed an exceptionally brave and risky humanitarian act by accepting to house and care for 1300 Jewish refugees in Šabac, Serbia, during the summer of 1940, “when no one else dared.”1 It was a ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • Memories of a Jewish Family in Šabac
    • Abstract: Prior to World War I Šabac, like other Serbian cities, had a Jewish population. According to the 1910 census there were 132 Jewish families. However, after the end of the war, only 18 families remained in the city. Until 1941, when Nazi Germany occupied Serbia, Jewish families lived in every area of Šabac. While they engaged in a variety of professions, the majority were merchants who owned their own stores. Affordability and variety made their businesses successful. The Jewish community in Šabac had its own synagogue on Artillery Street (now Vlada Jovanović street), which still stands. In the fall of 1941, German occupiers, together with Croatian Ustaše, rounded up all the males in Šabac older ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • Sparks of Truth from the Hilly Balkans: Memories from Childhood
    • Abstract: I sit in the room. Outside it is quiet and only occasionally interrupted by the chirp of a bird, the sound of leaves rustling: one can smell the divine fragrance of nature. On the television screen flash the images and burst the sounds of war. Explosions! One can see demolished buildings, columns of refugees, hear the sounds of airplane motors, the cries of children; but one cannot perceive the smells of war. That must be experienced and survived. I suppose that is how it was in 1939, 1940, and the beginning of 1941 in Serbia. People’s memories of the horrors of the First World War were still fresh as the new war approached like a cloud. Those two-and-a-half to three years before Germany attacked ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • A Photographic Memoir: The Jewish Street in Belgrade
    • Abstract: Between 1928 and around 1932, Jeremija Stanojević, colonel in the Royal Yugoslav Army and professor in the Military Academy of Belgrade, undertook a very ambitious project. He wanted to create a photographic documentary of all the streets in Belgrade’s old city in order to record the old and new, both the destruction and new construction. An entire set of these negatives was destroyed in April 1941 during the German bombing of Belgrade, when the Military Academy suffered a direct hit to the section of the complex in which these negatives were kept. Fortuitously, however, more than 2,000 negatives stored in the Stanojević family home were saved, thus preserving images of many streets in the old city. ... Read More
      Keywords: Jews; Jewish cemeteries; Jewish families; Diplomats; Albala, David,; Serbia; United States; Serbian literature; Šomlo, Ana,; Kiš, Danilo,; Davičo, Oskar; Names, Geographical; Greenberg, Uri Zvi,; Sava River; Women political prisoners; Lebl, Ženi
      PubDate: 2017-07-17T00:00:00-05:00
       
  • Application of Combination High-Throughput Phenotypic Screening and Target
           Identification Methods for the Discovery of Natural Product-Based
           Combination Drugs
    • Authors: Monica Isgut; Mukkavilli Rao, Chunhua Yang, Vangala Subrahmanyam, Padmashree C. G. Rida, Ritu Aneja
      Abstract: Modern drug discovery efforts have had mediocre success rates with increasing developmental costs, and this has encouraged pharmaceutical scientists to seek innovative approaches. Recently with the rise of the fields of systems biology and metabolomics, network pharmacology (NP) has begun to emerge as a new paradigm in drug discovery, with a focus on multiple targets and drug combinations for treating disease. Studies on the benefits of drug combinations lay the groundwork for a renewed focus on natural products in drug discovery. Natural products consist of a multitude of constituents that can act on a variety of targets in the body to induce pharmacodynamic responses that may together culminate in an additive or synergistic therapeutic effect. Although natural products cannot be patented, they can be used as starting points in the discovery of potent combination therapeutics. The optimal mix of bioactive ingredients in natural products can be determined via phenotypic screening. The targets and molecular mechanisms of action of these active ingredients can then be determined using chemical proteomics, and by implementing a reverse pharmacokinetics approach. This review article provides evidence supporting the potential benefits of natural product-based combination drugs, and summarizes drug discovery methods that can be applied to this class of drugs.
      PubDate: 2017-05-16T08:56:00.639657-05:
      DOI: 10.1002/med.21444
       
  • Therapeutic Targeting of Poly(ADP-Ribose) Polymerase-1 (PARP1) in Cancer:
           Current Developments, Therapeutic Strategies, and Future Opportunities
    • Authors: Jyotika Rajawat; Nidhi Shukla, Durga Prasad Mishra
      Abstract: Poly(ADP-ribose) polymerase-1 (PARP-1) plays a central role in numerous cellular processes including DNA repair, replication, and transcription. PARP interacts directly, indirectly or via PARylation with various oncogenic proteins and regulates several transcription factors thereby modulating carcinogenesis. Therapeutic inhibition of PARP is therefore perceived as a promising anticancer strategy and a number of PARP inhibitors (PARPi) are currently under development and clinical evaluation. PARPi inhibit the DNA repair pathway and thus form the concept of synthetic lethality in cancer therapeutics. Preclinical and clinical studies have shown the potential of PARPi as chemopotentiator, radiosensitizer, or as adjuvant therapeutic agents. Recent studies have shown that PARP-1 could be either oncogenic or tumor suppressive in different cancers. PARP inhibitor resistance is also a growing concern in the clinical setting. Recently, changes in the levels of PARP-1 activity or expression in cancer patients have provided the basis for consideration of PARP-1 regulatory proteins as potential biomarkers. This review focuses on the current developments related to the role of PARP in cancer progression, therapeutic strategies targeting PARP-associated oncogenic signaling, and future opportunities in use of PARPi in anticancer therapeutics.
      PubDate: 2017-05-16T08:55:56.263851-05:
      DOI: 10.1002/med.21442
       
  • Development of Safe Drugs: The hERG Challenge
    • Authors: Subha Kalyaanamoorthy; Khaled H. Barakat
      Abstract: Drug-induced blockade of human ether-a-go-go-related gene (hERG) remains a major impediment in delivering safe drugs to the market. Several drugs have been withdrawn from the market due to their severe cardiotoxic side effects triggered by their off-target interactions with hERG. Thus, identifying the potential hERG blockers at early stages of lead discovery is fast evolving as a standard in drug design and development. A number of in silico structure-based models of hERG have been developed as a low-cost solution to evaluate drugs for hERG liability, and it is now agreed that the hERG blockers bind at the large central cavity of the channel. Nevertheless, there is no clear convergence on the appropriate drug binding modes against the channel. The proposed binding modes differ in their orientations and interpretations on the role of key residues in the channel. Such ambiguities in the modes of binding remain to be a significant challenge in achieving efficient computational predictive models and in saving many important already Food and Drug Administration approved drugs. In this review, we discuss the spectrum of reported binding modes for hERG blockers, the various in silico models developed for predicting a drug's affinity to hERG, and the known successful optimization strategies to avoid off-target interactions with hERG.
      PubDate: 2017-05-03T11:45:36.785568-05:
      DOI: 10.1002/med.21445
       
  • Bridging Type 2 Diabetes and Alzheimer's Disease: Assembling the Puzzle
           Pieces in the Quest for the Molecules With Therapeutic and Preventive
           Potential
    • Authors: Ana Marta de Matos; Maria Paula de Macedo, Amélia Pilar Rauter
      Abstract: Type 2 diabetes (T2D) and Alzheimer's disease (AD) are two age-related amyloid diseases that affect millions of people worldwide. Broadly supported by epidemiological data, the higher incidence of AD among type 2 diabetic patients led to the recognition of T2D as a tangible risk factor for the development of AD. Indeed, there is now growing evidence on brain structural and functional abnormalities arising from brain insulin resistance and deficiency, ultimately highlighting the need for new approaches capable of preventing the development of AD in type 2 diabetic patients. This review provides an update on overlapping pathophysiological mechanisms and pathways in T2D and AD, such as amyloidogenic events, oxidative stress, endothelial dysfunction, aberrant enzymatic activity, and even shared genetic background. These events will be presented as puzzle pieces put together, thus establishing potential therapeutic targets for drug discovery and development against T2D and diabetes-induced cognitive decline—a heavyweight contributor to the increasing incidence of dementia in developed countries. Hoping to pave the way in this direction, we will present some of the most promising and well-studied drug leads with potential against both pathologies, including their respective bioactivity reports, mechanisms of action, and structure–activity relationships.
      PubDate: 2017-04-19T06:37:13.293139-05:
      DOI: 10.1002/med.21440
       
  • Free Fatty Acid Receptor 1 (FFAR1) as an Emerging Therapeutic Target for
           Type 2 Diabetes Mellitus: Recent Progress and Prevailing Challenges
    • Authors: Zheng Li; Xue Xu, Wenlong Huang, Hai Qian
      Abstract: The free fatty acid receptor 1 (FFAR1/GPR40) amplifies glucose-dependent insulin secretion; therefore, it has attracted widespread attention as a promising antidiabetic target. Current clinical proof of concept also indicates that FFAR1 agonists achieve the initially therapeutic endpoint for the treatment of type 2 diabetes mellitus (T2DM) without the hypoglycemic risk. Thus, many pharmaceutical companies and academic institutes are competing to develop FFAR1 agonists. However, several candidates have been discontinued in clinical trials, often without reporting the underlying reasons. Herein, we review the challenges and corresponding strategies chosen by different medicinal chemistry teams to improve the physicochemical properties, potency, pharmacokinetics, and safety profiles of FFAR1 agonists, with a brief introduction to the biology and pharmacology of related targets.
      PubDate: 2017-03-22T06:32:23.192764-05:
      DOI: 10.1002/med.21441
       
  • Genome Engineering and Modification Toward Synthetic Biology for the
           Production of Antibiotics
    • Authors: Xuan Zou; Lianrong Wang, Zhiqiang Li, Jie Luo, Yunfu Wang, Zixin Deng, Shiming Du, Shi Chen
      Abstract: Antibiotic production is often governed by large gene clusters composed of genes related to antibiotic scaffold synthesis, tailoring, regulation, and resistance. With the expansion of genome sequencing, a considerable number of antibiotic gene clusters has been isolated and characterized. The emerging genome engineering techniques make it possible towards more efficient engineering of antibiotics. In addition to genomic editing, multiple synthetic biology approaches have been developed for the exploration and improvement of antibiotic natural products. Here, we review the progress in the development of these genome editing techniques used to engineer new antibiotics, focusing on three aspects of genome engineering: direct cloning of large genomic fragments, genome engineering of gene clusters, and regulation of gene cluster expression. This review will not only summarize the current uses of genomic engineering techniques for cloning and assembly of antibiotic gene clusters or for altering antibiotic synthetic pathways but will also provide perspectives on the future directions of rebuilding biological systems for the design of novel antibiotics.
      PubDate: 2017-03-15T01:15:49.105563-05:
      DOI: 10.1002/med.21439
       
  • Toward Hydrogen Sulfide Based Therapeutics: Critical Drug Delivery and
           Developability Issues
    • Authors: Yueqin Zheng; Bingchen Yu, Ladie Kimberly La Cruz, Manjusha Roy Choudhury, Abiodun Anifowose, Binghe Wang
      Abstract: Hydrogen sulfide (H2S), together with nitric oxide (NO) and carbon monoxide (CO), belongs to the gasotransmitter family and plays important roles in mammals as a signaling molecule. Many studies have also shown the various therapeutic effects of H2S, which include protection against myocardial ischemia injury, cytoprotection against oxidative stress, mediation of neurotransmission, inhibition of insulin signaling, regulation of inflammation, inhibition of the hypoxia-inducible pathway, and dilation of blood vessels. One major challenge in the development of H2S-based therapeutics is its delivery. In this manuscript, we assess the various drug delivery strategies in the context of being used research tools and eventual developability as therapeutic agents.
      PubDate: 2017-02-27T06:32:12.315124-05:
      DOI: 10.1002/med.21433
       
  • Atheroprotective Effects and Molecular Targets of Tanshinones Derived From
           Herbal Medicine Danshen
    • Authors: Jian Fang; Peter J. Little, Suowen Xu
      Abstract: Medicinal plant-derived bioactive compounds modulate multiple therapeutic targets in cardiovascular diseases (CVDs), rendering herb-derived phytochemicals effective against one of the major CVDs-atherosclerosis. Danshen (Salvia milthiorriza Bunge) is a Chinese medicine that has been used in cardio- and cerebro-vascular therapeutic remedies in Asian countries for many years. Emerging evidence from cellular, animal, and clinical studies suggests that major lipophilic tanshinones from Danshen can treat atherosclerotic CVDs. In this review, we highlight recent advances in understanding the molecular mechanisms of tanshinones in treating atherosclerosis, ranging from endothelial dysfunction to chronic inflammation. We also overview new molecular targets of tanshinones, including endothelial nitric oxide synthase, AMP-activated protein kinase, ABC transporter A1, heme oxygenase 1, soluble epoxide hydrolase, 11β-hydroxysteroid dehydrogenase, estrogen receptor, and proprotein convertase subtilisin/kexin type 9. Thus, this review provides a new perspective for advancing our understanding of the “ancient” herb Danshen from “modern” biomedical perspectives, supporting the possibility of exploiting tanshinones and derivatives as effective therapeutics against atherosclerosis-related cardiovascular and metabolic diseases.
      PubDate: 2017-02-16T07:50:31.05418-05:0
      DOI: 10.1002/med.21438
       
  • The Search for Potent, Small-Molecule HDACIs in Cancer Treatment: A Decade
           After Vorinostat
    • Authors: Chiara Zagni; Giuseppe Floresta, Giulia Monciino, Antonio Rescifina
      Abstract: Histone deacetylases (HDACs) play a crucial role in the remodeling of chromatin, and are involved in the epigenetic regulation of gene expression. In the last decade, inhibition of HDACs came out as a target for specific epigenetic changes associated with cancer and other diseases. Until now, more than 20 HDAC inhibitors (HDACIs) have entered clinical studies, and some of them (e.g., vorinostat, romidepsin) have been approved for the treatment of cutaneous T-cell lymphoma. This review provides an overview of current knowledge, progress, and molecular mechanisms of HDACIs, covering a period from 2011 until 2015.
      PubDate: 2017-02-09T04:40:40.514955-05:
      DOI: 10.1002/med.21437
       
  • Potential Therapeutic Applications of Adenosine A2A Receptor Ligands and
           Opportunities for A2A Receptor Imaging
    • Authors: Aren Waarde; Rudi A. J. O. Dierckx, Xiaoyun Zhou, Shivashankar Khanapur, Hideo Tsukada, Kiichi Ishiwata, Gert Luurtsema, Erik F. J. Vries, Philip H. Elsinga
      Abstract: Adenosine A2A receptors (A2ARs) are highly expressed in the human striatum, and at lower densities in the cerebral cortex, the hippocampus, and cells of the immune system. Antagonists of these receptors are potentially useful for the treatment of motor fluctuations, epilepsy, postischemic brain damage, or cognitive impairment, and for the control of an immune checkpoint during immunotherapy of cancer. A2AR agonists may suppress transplant rejection and graft-versus-host disease; be used to treat inflammatory disorders such as asthma, inflammatory bowel disease, and rheumatoid arthritis; be locally applied to promote wound healing and be employed in a strategy for transient opening of the blood–brain barrier (BBB) so that therapeutic drugs and monoclonal antibodies can enter the brain. Increasing A2AR signaling in adipose tissue is also a potential strategy to combat obesity. Several radioligands for positron emission tomography (PET) imaging of A2ARs have been developed in recent years. This review article presents a critical overview of the potential therapeutic applications of A2AR ligands, the use of A2AR imaging in drug development, and opportunities and limitations of PET imaging in future research.
      PubDate: 2017-01-27T07:56:18.474784-05:
      DOI: 10.1002/med.21432
       
  • The Current State of NAD+-Dependent Histone Deacetylases (Sirtuins) as
           Novel Therapeutic Targets
    • Authors: Matthias Schiedel; Dina Robaa, Tobias Rumpf, Wolfgang Sippl, Manfred Jung
      Abstract: Sirtuins are NAD+-dependent protein deacylases that cleave off acetyl, as well as other acyl groups, from the ε-amino group of lysines in histones and other substrate proteins. Seven sirtuin isotypes (Sirt1–7) have been identified in mammalian cells. As sirtuins are involved in the regulation of various physiological processes such as cell survival, cell cycle progression, apoptosis, DNA repair, cell metabolism, and caloric restriction, a dysregulation of their enzymatic activity has been associated with the pathogenesis of neoplastic, metabolic, infectious, and neurodegenerative diseases. Thus, sirtuins are promising targets for pharmaceutical intervention. Growing interest in a modulation of sirtuin activity has prompted the discovery of several small molecules, able to inhibit or activate certain sirtuin isotypes. Herein, we give an update to our previous review on the topic in this journal (Schemies, 2010), focusing on recent developments in sirtuin biology, sirtuin modulators, and their potential as novel therapeutic agents.
      PubDate: 2017-01-17T08:21:05.428031-05:
      DOI: 10.1002/med.21436
       
  • Human Antimicrobial Peptides in Bodily Fluids: Current Knowledge and
           Therapeutic Perspectives in the Postantibiotic Era
    • Authors: Paulo Bastos; Fábio Trindade, João da Costa, Rita Ferreira, Rui Vitorino
      Abstract: Antimicrobial peptides (AMPs) are an integral part of the innate immune defense mechanism of many organisms. Due to the alarming increase of resistance to antimicrobial therapeutics, a growing interest in alternative antimicrobial agents has led to the exploitation of AMPs, both synthetic and isolated from natural sources. Thus, many peptide-based drugs have been the focus of increasing attention by many researchers not only in identifying novel AMPs, but in defining mechanisms of antimicrobial peptide activity as well. Herein, we review the available strategies for the identification of AMPs in human body fluids and their mechanism(s) of action. In addition, an overview of the distribution of AMPs across different human body fluids is provided, as well as its relation with microorganisms and infectious conditions.
      PubDate: 2017-01-17T05:46:50.067839-05:
      DOI: 10.1002/med.21435
       
  • Drugs in Clinical Trials for Alzheimer's Disease: The Major Trends
    • Authors: Sergey O. Bachurin; Elena V. Bovina, Aleksey A. Ustyugov
      Abstract: Alzheimer's disease (AD) is characterized by a chronic and progressive neurodegenerative process resulting from the intracellular and extracellular accumulation of fibrillary proteins: beta-amyloid and hyperphosphorylated Tau. Overaccumulation of these aggregates leads to synaptic dysfunction and subsequent neuronal loss. The precise molecular mechanisms of AD are still not fully understood but it is clear that AD is a multifactorial disorder and that advanced age is the main risk factor. Over the last decade, more than 50 drug candidates have successfully passed phase II clinical trials, but none has passed phase III. Here, we summarize data on current “anti-Alzheimer's” agents currently in clinical trials based on findings available in the Thomson Reuters «Integrity» database, on the public website www.clinicaltrials.gov, and on database of the website Alzforum.org. As a result, it was possible to outline some major trends in AD drug discovery: (i) the development of compounds acting on the main stages of the pathogenesis of the disease (the so-called “disease-modifying agents”) — these drugs could potentially slow the development of structural and functional abnormalities in the central nervous system providing sustainable improvements of cognitive functions, which persist even after drug withdrawal; (ii) focused design of multitargeted drugs acting on multiple molecular targets involved in the pathogenesis of the disease; (3) finally, the repositioning of old drugs for new (anti-Alzheimer's) application offers a very attractive approach to facilitate the completion of clinical trials.
      PubDate: 2017-01-13T07:25:57.038684-05:
      DOI: 10.1002/med.21434
       
  • Understanding the Molecular Mechanisms of the Interplay Between Herbal
           Medicines and Gut Microbiota
    • Authors: Jun Xu; Hu-Biao Chen, Song-Lin Li
      Abstract: Herbal medicines (HMs) are much appreciated for their significant contribution to human survival and reproduction by remedial and prophylactic management of diseases. Defining the scientific basis of HMs will substantiate their value and promote their modernization. Ever-increasing evidence suggests that gut microbiota plays a crucial role in HM therapy by complicated interplay with HM components. This interplay includes such activities as: gut microbiota biotransforming HM chemicals into metabolites that harbor different bioavailability and bioactivity/toxicity from their precursors; HM chemicals improving the composition of gut microbiota, consequently ameliorating its dysfunction as well as associated pathological conditions; and gut microbiota mediating the interactions (synergistic and antagonistic) between the multiple chemicals in HMs. More advanced experimental designs are recommended for future study, such as overall chemical characterization of gut microbiota-metabolized HMs, direct microbial analysis of HM-targeted gut microbiota, and precise gut microbiota research model development. The outcomes of such research can further elucidate the interactions between HMs and gut microbiota, thereby opening a new window for defining the scientific basis of HMs and for guiding HM-based drug discovery.
      PubDate: 2017-01-04T09:00:29.197409-05:
      DOI: 10.1002/med.21431
       
  • Issue Information - TOC
    • Pages: 663 - 664
      PubDate: 2017-06-09T17:04:27.410389-05:
      DOI: 10.1002/med.21414
       
 
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