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Publisher: Medknow Publishers   (Total: 355 journals)

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Showing 1 - 200 of 355 Journals sorted alphabetically
Advanced Arab Academy of Audio-Vestibulogy J.     Open Access  
Advances in Human Biology     Open Access   (Followers: 2)
African J. for Infertility and Assisted Conception     Open Access  
African J. of Business Ethics     Open Access   (Followers: 6)
African J. of Medical and Health Sciences     Open Access   (Followers: 2)
African J. of Paediatric Surgery     Open Access   (Followers: 7, SJR: 0.269, h-index: 10)
African J. of Trauma     Open Access  
Ain-Shams J. of Anaesthesiology     Open Access   (Followers: 3)
Al-Azhar Assiut Medical J.     Open Access  
Al-Basar Intl. J. of Ophthalmology     Open Access   (Followers: 1)
Ancient Science of Life     Open Access   (Followers: 5)
Anesthesia : Essays and Researches     Open Access   (Followers: 9)
Annals of African Medicine     Open Access   (Followers: 1, SJR: 0.331, h-index: 15)
Annals of Bioanthropology     Open Access   (Followers: 4)
Annals of Cardiac Anaesthesia     Open Access   (Followers: 14, SJR: 0.408, h-index: 15)
Annals of Indian Academy of Neurology     Open Access   (Followers: 3, SJR: 0.308, h-index: 14)
Annals of Maxillofacial Surgery     Open Access   (Followers: 6)
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 7, SJR: 0.441, h-index: 10)
Annals of Saudi Medicine     Open Access   (SJR: 0.24, h-index: 29)
Annals of Thoracic Medicine     Open Access   (Followers: 5, SJR: 0.388, h-index: 19)
Annals of Tropical Medicine and Public Health     Open Access   (Followers: 12, SJR: 0.148, h-index: 5)
APOS Trends in Orthodontics     Open Access   (Followers: 1)
Arab J. of Interventional Radiology     Open Access  
Archives of Intl. Surgery     Open Access   (Followers: 10)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Archives of Pharmacy Practice     Open Access   (Followers: 6)
Asia Pacific J. of Clinical Trials : Nervous System Diseases     Open Access  
Asia-Pacific J. of Oncology Nursing     Open Access   (Followers: 4)
Asian J. of Andrology     Open Access   (Followers: 1, SJR: 0.879, h-index: 49)
Asian J. of Neurosurgery     Open Access   (Followers: 2)
Asian J. of Oncology     Open Access   (Followers: 1)
Asian J. of Transfusion Science     Open Access   (Followers: 1, SJR: 0.362, h-index: 10)
Astrocyte     Open Access  
Avicenna J. of Medicine     Open Access   (Followers: 1)
AYU : An international quarterly journal of research in Ayurveda     Open Access   (Followers: 6)
Benha Medical J.     Open Access  
BLDE University J. of Health Sciences     Open Access  
Brain Circulation     Open Access  
Bulletin of Faculty of Physical Therapy     Open Access   (Followers: 1)
Cancer Translational Medicine     Open Access   (Followers: 2)
CHRISMED J. of Health and Research     Open Access  
Clinical Dermatology Review     Open Access   (Followers: 2)
Clinical Trials in Degenerative Diseases     Open Access  
Clinical Trials in Orthopedic Disorders     Open Access  
Community Acquired Infection     Open Access  
Conservation and Society     Open Access   (Followers: 10, SJR: 0.82, h-index: 12)
Contemporary Clinical Dentistry     Open Access   (Followers: 4)
Current Medical Issues     Open Access   (Followers: 1)
CytoJ.     Open Access   (Followers: 2, SJR: 0.339, h-index: 19)
Delta J. of Ophthalmology     Open Access  
Dental Hypotheses     Open Access   (Followers: 3, SJR: 0.131, h-index: 4)
Dental Research J.     Open Access   (Followers: 11)
Dentistry and Medical Research     Open Access  
Digital Medicine     Open Access  
Drug Development and Therapeutics     Open Access  
Education for Health     Open Access   (Followers: 6, SJR: 0.205, h-index: 22)
Egyptian J. of Bronchology     Open Access  
Egyptian J. of Cardiothoracic Anesthesia     Open Access  
Egyptian J. of Cataract and Refractive Surgery     Open Access   (Followers: 1)
Egyptian J. of Dermatology and Venerology     Open Access   (Followers: 1)
Egyptian J. of Haematology     Open Access   (Followers: 1)
Egyptian J. of Internal Medicine     Open Access   (Followers: 1)
Egyptian J. of Neurology, Psychiatry and Neurosurgery     Open Access   (Followers: 1, SJR: 0.121, h-index: 3)
Egyptian J. of Obesity, Diabetes and Endocrinology     Open Access  
Egyptian J. of Otolaryngology     Open Access   (Followers: 2)
Egyptian J. of Psychiatry     Open Access   (Followers: 2)
Egyptian J. of Surgery     Open Access   (Followers: 1)
Egyptian Orthopaedic J.     Open Access   (Followers: 1)
Egyptian Pharmaceutical J.     Open Access  
Egyptian Retina J.     Open Access  
Egyptian Rheumatology and Rehabilitation     Open Access  
Endodontology     Open Access  
Endoscopic Ultrasound     Open Access   (SJR: 0.473, h-index: 8)
Environmental Disease     Open Access   (Followers: 2)
European J. of Dentistry     Open Access   (Followers: 2, SJR: 0.496, h-index: 11)
European J. of General Dentistry     Open Access   (Followers: 1)
European J. of Prosthodontics     Open Access   (Followers: 3)
European J. of Psychology and Educational Studies     Open Access   (Followers: 11)
Fertility Science and Research     Open Access  
Formosan J. of Surgery     Open Access   (SJR: 0.107, h-index: 5)
Genome Integrity     Open Access   (Followers: 3, SJR: 1.227, h-index: 12)
Global J. of Transfusion Medicine     Open Access   (Followers: 1)
Heart India     Open Access   (Followers: 1)
Heart Views     Open Access   (Followers: 2)
Hepatitis B Annual     Open Access   (Followers: 3)
IJS Short Reports     Open Access  
Indian Anaesthetists Forum     Open Access  
Indian Dermatology Online J.     Open Access   (Followers: 3)
Indian J. of Allergy, Asthma and Immunology     Open Access   (Followers: 1)
Indian J. of Anaesthesia     Open Access   (Followers: 7, SJR: 0.302, h-index: 13)
Indian J. of Burns     Open Access   (Followers: 1)
Indian J. of Cancer     Open Access   (Followers: 1, SJR: 0.318, h-index: 26)
Indian J. of Cerebral Palsy     Open Access   (Followers: 1)
Indian J. of Community Medicine     Open Access   (Followers: 2, SJR: 0.618, h-index: 16)
Indian J. of Critical Care Medicine     Open Access   (Followers: 2, SJR: 0.307, h-index: 16)
Indian J. of Dental Research     Open Access   (Followers: 4, SJR: 0.243, h-index: 24)
Indian J. of Dental Sciences     Open Access  
Indian J. of Dentistry     Open Access   (Followers: 1)
Indian J. of Dermatology     Open Access   (Followers: 2, SJR: 0.448, h-index: 16)
Indian J. of Dermatology, Venereology and Leprology     Open Access   (Followers: 4, SJR: 0.563, h-index: 29)
Indian J. of Dermatopathology and Diagnostic Dermatology     Open Access  
Indian J. of Drugs in Dermatology     Open Access   (Followers: 1)
Indian J. of Endocrinology and Metabolism     Open Access   (Followers: 4)
Indian J. of Health Sciences     Open Access   (Followers: 2)
Indian J. of Medical and Paediatric Oncology     Open Access   (SJR: 0.292, h-index: 9)
Indian J. of Medical Microbiology     Open Access   (Followers: 1, SJR: 0.53, h-index: 34)
Indian J. of Medical Research     Open Access   (Followers: 4, SJR: 0.716, h-index: 60)
Indian J. of Medical Sciences     Open Access   (Followers: 2, SJR: 0.207, h-index: 31)
Indian J. of Multidisciplinary Dentistry     Open Access   (Followers: 1)
Indian J. of Nephrology     Open Access   (Followers: 2, SJR: 0.233, h-index: 12)
Indian J. of Nuclear Medicine     Open Access   (Followers: 2, SJR: 0.213, h-index: 5)
Indian J. of Occupational and Environmental Medicine     Open Access   (Followers: 3, SJR: 0.203, h-index: 13)
Indian J. of Ophthalmology     Open Access   (Followers: 5, SJR: 0.536, h-index: 34)
Indian J. of Oral Health and Research     Open Access  
Indian J. of Oral Sciences     Open Access   (Followers: 1)
Indian J. of Orthopaedics     Open Access   (Followers: 8, SJR: 0.393, h-index: 15)
Indian J. of Otology     Open Access   (Followers: 1, SJR: 0.218, h-index: 5)
Indian J. of Paediatric Dermatology     Open Access   (Followers: 2)
Indian J. of Pain     Open Access   (Followers: 1)
Indian J. of Palliative Care     Open Access   (Followers: 5, SJR: 0.35, h-index: 12)
Indian J. of Pathology and Microbiology     Open Access   (Followers: 2, SJR: 0.285, h-index: 22)
Indian J. of Pharmacology     Open Access   (SJR: 0.347, h-index: 44)
Indian J. of Plastic Surgery     Open Access   (Followers: 12, SJR: 0.303, h-index: 13)
Indian J. of Psychiatry     Open Access   (Followers: 3, SJR: 0.496, h-index: 15)
Indian J. of Psychological Medicine     Open Access   (SJR: 0.344, h-index: 9)
Indian J. of Public Health     Open Access   (Followers: 1, SJR: 0.444, h-index: 17)
Indian J. of Radiology and Imaging     Open Access   (Followers: 4, SJR: 0.253, h-index: 14)
Indian J. of Research in Homoeopathy     Open Access  
Indian J. of Rheumatology     Open Access   (SJR: 0.169, h-index: 7)
Indian J. of Sexually Transmitted Diseases and AIDS     Open Access   (Followers: 2, SJR: 0.313, h-index: 9)
Indian J. of Social Psychiatry     Open Access   (Followers: 2)
Indian J. of Urology     Open Access   (Followers: 3, SJR: 0.366, h-index: 16)
Indian J. of Vascular and Endovascular Surgery     Open Access   (Followers: 2)
Industrial Psychiatry J.     Open Access   (Followers: 2)
Intl. J. of Academic Medicine     Open Access  
Intl. J. of Advanced Medical and Health Research     Open Access  
Intl. J. of Applied and Basic Medical Research     Open Access  
Intl. J. of Clinical and Experimental Physiology     Open Access   (Followers: 1)
Intl. J. of Critical Illness and Injury Science     Open Access   (Followers: 1)
Intl. J. of Educational and Psychological Researches     Open Access   (Followers: 4)
Intl. J. of Environmental Health Engineering     Open Access   (Followers: 1)
Intl. J. of Forensic Odontology     Open Access   (Followers: 1)
Intl. J. of Green Pharmacy     Open Access   (Followers: 3, SJR: 0.229, h-index: 13)
Intl. J. of Health & Allied Sciences     Open Access   (Followers: 3)
Intl. J. of Health System and Disaster Management     Open Access   (Followers: 3)
Intl. J. of Heart Rhythm     Open Access  
Intl. J. of Medicine and Public Health     Open Access   (Followers: 6)
Intl. J. of Mycobacteriology     Open Access   (SJR: 0.239, h-index: 4)
Intl. J. of Noncommunicable Diseases     Open Access  
Intl. J. of Nutrition, Pharmacology, Neurological Diseases     Open Access   (Followers: 4)
Intl. J. of Oral Health Sciences     Open Access   (Followers: 2)
Intl. J. of Orthodontic Rehabilitation     Open Access  
Intl. J. of Pedodontic Rehabilitation     Open Access  
Intl. J. of Pharmaceutical Investigation     Open Access   (Followers: 1)
Intl. J. of Preventive Medicine     Open Access   (Followers: 1, SJR: 0.523, h-index: 15)
Intl. J. of Shoulder Surgery     Open Access   (Followers: 5, SJR: 0.611, h-index: 9)
Intl. J. of Trichology     Open Access   (SJR: 0.37, h-index: 10)
Intl. J. of Yoga     Open Access   (Followers: 13)
Intl. J. of Yoga : Philosophy, Psychology and Parapsychology     Open Access   (Followers: 5)
Iranian J. of Nursing and Midwifery Research     Open Access   (Followers: 3)
Iraqi J. of Hematology     Open Access  
J. of Academy of Medical Sciences     Open Access  
J. of Advanced Pharmaceutical Technology & Research     Open Access   (Followers: 3, SJR: 0.427, h-index: 15)
J. of Anaesthesiology Clinical Pharmacology     Open Access   (Followers: 7, SJR: 0.416, h-index: 14)
J. of Applied Hematology     Open Access   (Followers: 1)
J. of Association of Chest Physicians     Open Access   (Followers: 2)
J. of Basic and Clinical Reproductive Sciences     Open Access   (Followers: 1)
J. of Cancer Research and Therapeutics     Open Access   (Followers: 5, SJR: 0.359, h-index: 21)
J. of Carcinogenesis     Open Access   (Followers: 1, SJR: 1.152, h-index: 26)
J. of Cardiothoracic Trauma     Open Access  
J. of Cardiovascular Disease Research     Open Access   (Followers: 3, SJR: 0.351, h-index: 13)
J. of Cardiovascular Echography     Open Access   (Followers: 1, SJR: 0.134, h-index: 2)
J. of Cleft Lip Palate and Craniofacial Anomalies     Open Access   (Followers: 2)
J. of Clinical and Preventive Cardiology     Open Access   (Followers: 1)
J. of Clinical Imaging Science     Open Access   (Followers: 1, SJR: 0.277, h-index: 8)
J. of Clinical Neonatology     Open Access   (Followers: 2)
J. of Clinical Ophthalmology and Research     Open Access   (Followers: 3)
J. of Clinical Sciences     Open Access  
J. of Conservative Dentistry     Open Access   (Followers: 4, SJR: 0.532, h-index: 10)
J. of Craniovertebral Junction and Spine     Open Access   (Followers: 4, SJR: 0.199, h-index: 9)
J. of Current Medical Research and Practice     Open Access  
J. of Current Research in Scientific Medicine     Open Access  
J. of Cutaneous and Aesthetic Surgery     Open Access   (Followers: 1)
J. of Cytology     Open Access   (Followers: 1, SJR: 0.274, h-index: 9)
J. of Dental and Allied Sciences     Open Access   (Followers: 2)
J. of Dental Implants     Open Access   (Followers: 7)
J. of Dental Lasers     Open Access   (Followers: 2)
J. of Dental Research and Review     Open Access   (Followers: 1)
J. of Digestive Endoscopy     Open Access   (Followers: 2)
J. of Dr. NTR University of Health Sciences     Open Access  
J. of Earth, Environment and Health Sciences     Open Access   (Followers: 1)
J. of Education and Ethics in Dentistry     Open Access   (Followers: 5)
J. of Education and Health Promotion     Open Access   (Followers: 5)
J. of Emergencies, Trauma and Shock     Open Access   (Followers: 9, SJR: 0.353, h-index: 14)
J. of Engineering and Technology     Open Access   (Followers: 6)
J. of Experimental and Clinical Anatomy     Open Access   (Followers: 2)
J. of Family and Community Medicine     Open Access   (Followers: 2)
J. of Family Medicine and Primary Care     Open Access   (Followers: 11)

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Journal Cover Journal of Current Medical Research and Practice
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   ISSN (Print) 2357-0121 - ISSN (Online) 2357-013X
   Published by Medknow Publishers Homepage  [355 journals]
  • Comparison of chirp and click-evoked brainstem response stimulus in
           children with moderate and severe sensorineural hearing loss

    • Authors: Amal M El-Attar, Sayed M Enass, Mossa M Hoda Abu, Mahran M Sanaa
      Pages: 99 - 104
      Abstract: Amal M El-Attar, Sayed M Enass, Mossa M Hoda Abu, Mahran M Sanaa
      Journal of Current Medical Research and Practice 2017 2(2):99-104
      IntroductionAuditory brainstem response using click stimuli enable global objective estimation of hearing threshold. Recently, it has been suggested that a chirp stimulus may produce a synchronous response from a large portion of basilar membrane. The chirp was designed to produce simultaneous displacement maxima along the cochlear partition by compensating for frequency-dependent traveling-time differences. Material and methodsIn this study, response characteristic of both click and chirp stimuli are compared in children. We compared latency and amplitude of wave V at different intensity levels and waves I and III at high level. Results and conclusionResults show that wave V on using chirp stimuli could be detected easier with shorted in latency and larger in amplitude than in click auditory brainstem response. However, click stimulus was better than chirp stimulus at high-intensity levels with respect to the identification of waves I and III.
      Citation: Journal of Current Medical Research and Practice 2017 2(2):99-104
      PubDate: Mon,6 Nov 2017
      DOI: 10.4103/JCMRP.JCMRP_1_17
      Issue No: Vol. 2, No. 2 (2017)
       
  • Doxorubicin-eluting beads versus combined conventional transarterial
           chemoembolization and percutaneous alcohol injection in the treatment of
           large hepatocellular carcinoma

    • Authors: Ahlam M. A. Farghaly, EhabFawzy A Moustafa, Hany M. A. Seif, Moustafa H. M. Othman, Reda H. M. Tabashy, Mohammed O. A. Abdelglil, Essam Eldeen M. O. Mahran
      Pages: 105 - 110
      Abstract: Ahlam M. A. Farghaly, EhabFawzy A Moustafa, Hany M. A. Seif, Moustafa H. M. Othman, Reda H. M. Tabashy, Mohammed O. A. Abdelglil, Essam Eldeen M. O. Mahran
      Journal of Current Medical Research and Practice 2017 2(2):105-110
      IntroductionHepatocellular carcinoma (HCC) is a primary tumor of the liver, which usually develops in the setting of chronic liver disease, particularly in patients with chronic hepatitis B and hepatitis C. Current guidelines recommend transarterial chemoembolization (TACE) as the standard treatment of Barcelona Clinic Liver Cancer-B patients. The aim of this work is to compare the efficacy, safety, feasibility, and cost-effectiveness of drug-eluting bead (DEB)-TACE versus combined conventional transarterial chemoembolization (c-TACE)+percutaneous ethanol injection (PEI) for improving the outcome of large HCC.Patients and methodsIn all, 75 patients with large HCC were included in this study: 30 patients were treated by combined c-TACE + PEI and 45 patients were treated by DEB-TACE.ResultsBy comparison of the results of the combined c-TACE + PEI group with the DEB-TACE group, there was no significant difference in tumor response, with better results in the combined c-TACE + PEI group and significant decrease in the median value of the serum level of α-fetoprotein after treatment among patients treated with combined c-TACE + PEI (P = 0.004), and a statistically significant difference in the median value after treatment between the two groups (P = 0.036).ConclusionResults of combined c-TACE + PEI and DEB-TACE are comparable, but the cost of a DEB-TACE session is three times that of c-TACE + PEI, and thus cost-effectiveness analyses recommend the use of combined c-TACE + PEI (less cost) in the treatment of large HCC; in addition, there was a significant reduction in the level of α-fetoprotein after combined c-TACE+PEI treatment.
      Citation: Journal of Current Medical Research and Practice 2017 2(2):105-110
      PubDate: Mon,6 Nov 2017
      DOI: 10.4103/JCMRP.JCMRP_2_17
      Issue No: Vol. 2, No. 2 (2017)
       
  • Evaluation of visual and refractive outcomes of wavefront optimized versus
           wavefront guided laser-assisted in situ keratomileusis in patients with
           myopia and myopic astigmatism

    • Authors: Gamal N Mahmoud, Tamer H Massoud, Ahmed M Fathlla, Asmaa K Ahmed
      Pages: 111 - 118
      Abstract: Gamal N Mahmoud, Tamer H Massoud, Ahmed M Fathlla, Asmaa K Ahmed
      Journal of Current Medical Research and Practice 2017 2(2):111-118
      PurposeThe aim of this study was to compare the visual and refractive outcomes of wavefront optimized (WFO) ablations with wavefront guided (WFG) ablations in patients with myopia and myopic astigmatism.Patients and methodsTwo consecutive groups of eyes were treated for myopia and myopic astigmatism with laser insitu keratomileusis. One group was treated with WFO ablation, and the other group was treated with WFG ablation. Refractive evaluation (efficacy, safety, predictability, accuracy, stability, and refractive astigmatism), higher-order aberrations (HOAs), and contrast sensitivity were analyzed preoperatively and at 1, 3, and 6 months postoperatively.ResultsThe WFO ablation group comprised 20 eyes of 11 patients who showed a change in the mean spherical equivalent refraction from − 3.34 ± 1.64 D preoperatively to − 0.21 ± 0.30 D at 6 months postoperatively, and the WFG ablation group comprised 34 eyes of 17 patients who showed a change in the mean spherical equivalent refraction from − 3.54 ± 1.50 D preoperatively to − 0.23 ± 0.57 D at 6 months postoperatively. A statistically significant difference was found when comparing within the group preoperatively versus 6 months postoperatively as regards contrast sensitivity, HOAs, trefoil root mean square (RMS), and spherical aberration. However, there was no significant difference in induced coma and spherical aberration RMS within each group preoperatively and at 6 months postoperatively. A statistically significant difference was found when comparing the two groups at 6 months postoperatively with respect to contrast sensitivity, induced HOA RMS, induced trefoil RMS, and spherical aberration. There was no significant difference between the two groups, except for induced coma and spherical aberration RMS.ConclusionBoth the WFG group and the WFO showed comparable accuracy, efficacy, and safety with nearly equal induction of all HOAs.
      Citation: Journal of Current Medical Research and Practice 2017 2(2):111-118
      PubDate: Mon,6 Nov 2017
      DOI: 10.4103/JCMRP.JCMRP_4_17
      Issue No: Vol. 2, No. 2 (2017)
       
  • Complications of arteriovenous fistula in dialysis patients at Assiut
           University Hospital

    • Authors: Bahgat Abd El-Hamed Thabet, Mohamed O Ewas, Haitham A Hassan, Magy N Kamel
      Pages: 119 - 124
      Abstract: Bahgat Abd El-Hamed Thabet, Mohamed O Ewas, Haitham A Hassan, Magy N Kamel
      Journal of Current Medical Research and Practice 2017 2(2):119-124
      BackgroundRepeated access to the circulation is essential to perform adequate maintenance hemodialysis. Dysfunction of fistulas is the most common reason for secondary intervention and recurrent hospitalization.AimThe aim of this study was to report our experience regarding incidence, diagnosis, and different modalities of treatment of complications of arteriovenous fistula.Patients and methodsThis study was conducted prospectively on 239 end-stage renal disease patients who presented to the Department of Vascular Surgery of Assiut University Hospital with complicated arteriovenous (AV) accesses from January 2014 to January 2015. All patients underwent detailed history taking, and data were collected on age, sex, cardiovascular risk factors, history of previous accesses, and any complications that developed since the use of the access. Patients were further evaluated using clinical examination, duplex ultrasound, and fistulography if needed.ResultsThere were 137 (42.7%) males and 102 (42.7%) females with a mean age of 57 ± 4 years. Hypertension was the risk factor in 103 (43.1%) patients, whereas diabetes mellitus was present in 45 patients. Of the 239 patients, 57 (23.8%) presented with infected AV access, 42 (17.6%) with thrombosed AV accesses, 33 (13.8%) with bleeding, and 31 (12.9%) with pseudoaneurysms. Venous hypertension was the presenting complication in 26 (10.9%) patients, whereas aneurysmal dilatation, hematoma, and ischemic steal were the presenting complications in 25 (10.5%), 20 (8.4%), and 5 (2.1%) patients, respectively.ConclusionComplications of hemodialysis access create significant problems for nephrologists and the healthcare system. Access interventions are often costly, challenging, and may require specialized surgical expertise. Management of complications associated with AV access is an integral part of planning individual hemoaccess procedures.
      Citation: Journal of Current Medical Research and Practice 2017 2(2):119-124
      PubDate: Mon,6 Nov 2017
      DOI: 10.4103/JCMRP.JCMRP_32_16
      Issue No: Vol. 2, No. 2 (2017)
       
  • Relationship between serum leptin concentration and insulin resistance
           syndrome in patients with type 2 diabetes mellitus

    • Authors: Tamer H Shebl, Noor El Deen A Azeem, Hosny A Younis, Ahmed M Soliman, Ahmed M Ashmawy, Mohamed M Nuseir Ali
      Pages: 125 - 132
      Abstract: Tamer H Shebl, Noor El Deen A Azeem, Hosny A Younis, Ahmed M Soliman, Ahmed M Ashmawy, Mohamed M Nuseir Ali
      Journal of Current Medical Research and Practice 2017 2(2):125-132
      IntroductionType 2 diabetes mellitus is known for its morbidity and mortality worldwide. It has been demonstrated in recent studies that abnormal levels of adipocytokines may contribute to insulin resistance and type 2 diabetes.ObjectiveThe aim of the present study was to assess the relationship between serum leptin levels and insulin resistance syndrome in type 2 diabetic patients.Patients and methodsA total of 80 individuals were enrolled into this study, and were divided into two groups –20 healthy persons comprised the control group and 60 patients with type 2 diabetes mellitus comprised the disease group. The disease group was further divided into those with evidence of metabolic syndrome (30 patients) and those without (30 patients). Parameters such as age, sex, and anthropometric measures and biochemical indicators such as fasting and postprandial blood sugar, HbA1c, lipid profile, leptin, and fasting insulin were determined.ResultsHigher leptin and insulin levels were observed in patients with metabolic syndrome (P < 0.001).ConclusionHigh serum leptin is a good indicator and can act as a minimally invasive marker for early detection of insulin resistance syndrome.
      Citation: Journal of Current Medical Research and Practice 2017 2(2):125-132
      PubDate: Mon,6 Nov 2017
      DOI: 10.4103/JCMRP.JCMRP_33_16
      Issue No: Vol. 2, No. 2 (2017)
       
  • Serum level of interleukin-22 in patients with psoriasis and its
           correlation with disease severity

    • Authors: Eman R. M. Hofny, Hanan Morsy, Ashraf Hasaball, Howida Twisy
      Pages: 133 - 135
      Abstract: Eman R. M. Hofny, Hanan Morsy, Ashraf Hasaball, Howida Twisy
      Journal of Current Medical Research and Practice 2017 2(2):133-135
      IntroductionPsoriasis is a T-cell-mediated inflammatory disease where T-helper (Th) lymphocytes (Th1, Th17, and Th22) play an important role in its pathogenesis. The aim of the present study was to assess the serum levels of interleukin (IL)-22 and its correlation with disease severity.Materials and methodsThe present study included 25 psoriatic patients and 25 healthy controls. Using serum samples collected from psoriatic patients and healthy controls, the concentrations of IL-22 were examined using ELISA kits. The severity of psoriatic skin lesions was assessed using psoriasis area and severity index scores.ResultsIL-22 concentrations were significantly higher in psoriatic patients in comparison with the control group. A significant, positive correlation between the concentrations of IL-22 and the severity of psoriasis was found.ConclusionThe results of our study suggest that Th22 along with its cytokine responses may contribute to the skin and systemic inflammatory conditions characteristic of psoriasis. It seems that early identification of soluble biomarkers and initiation of well-matched treatment may prevent exacerbation and progression of psoriasis.
      Citation: Journal of Current Medical Research and Practice 2017 2(2):133-135
      PubDate: Mon,6 Nov 2017
      DOI: 10.4103/JCMRP.JCMRP_27_16
      Issue No: Vol. 2, No. 2 (2017)
       
  • Auditory brainstem response to chirp stimulus in children with moderate
           and severe sensorineural hearing loss

    • Authors: Amal M El-Attar, Sayed M Enass, Mossa M Hoda Abu, Mahran M Sanaa
      Pages: 136 - 140
      Abstract: Amal M El-Attar, Sayed M Enass, Mossa M Hoda Abu, Mahran M Sanaa
      Journal of Current Medical Research and Practice 2017 2(2):136-140
      IntroductionClick auditory brainstem response (ABR) is abrupt, has a rapid onset, and has a broad spectrum nonfrequency-specific response. ABR needs good neural synchrony, i.e., the greater number of neurons that fire results in a larger response amplitude. Recently, it has been suggested that a chirp stimulus may produce a synchronous response from a large portion of basilar membrane. The chirp was designed to produce simultaneous displacement maxima along the cochlear partition by compensating for frequency-dependent traveling time differences.Material and methodsIn this study, we attempt to find a correlation between pure tone threshold (PTA) and each of the click and chirp ABR thresholds in children with moderate and severe sensory neural hearing loss (SNHL). Results and conclusionsResults show that there is a significant correlation between chirp and behavioral PTA and between click and behavioral PTA in children with normal hearing and hearing impaired but not in those with severe steeping SNHL. In steeping SNHL, there was reduced correlation between behavioral PTA and click ABR stimuli. In addition, there was a significant correlation between narrow band-chirp at 500, 1000 Hz, and 4000 Hz and behavioral PTA in children with normal hearing loss and SNHL but not in those with severe steeping SNHL. In this category, there was a reduction in correlation between behavioral PTA and narrow band-chirp ABR stimuli.
      Citation: Journal of Current Medical Research and Practice 2017 2(2):136-140
      PubDate: Mon,6 Nov 2017
      DOI: 10.4103/JCMRP.JCMRP_25_16
      Issue No: Vol. 2, No. 2 (2017)
       
  • Posterior subtenon versus intravitreal triamcinolone acetonide injection
           for the treatment of diabetic macular edema

    • Authors: Mohamed G. A. Saleh, Mohamed T Abdelmoneim, Hassan L Fahmy, Ali N Riad, Phoebe Lin
      Pages: 141 - 149
      Abstract: Mohamed G. A. Saleh, Mohamed T Abdelmoneim, Hassan L Fahmy, Ali N Riad, Phoebe Lin
      Journal of Current Medical Research and Practice 2017 2(2):141-149
      BackgroundDiabetic macular edema (DME) is the most common cause of loss of vision in diabetic patients. The role of inflammation in the pathogenesis of DME has been demonstrated. An intravitreal (IVT) injection of triamcinolone acetonide (TA) is a treatment option for DME. The high incidence of side effects, however, limits the routine use of IVT TA.AimThe aim of this study was to compare the efficacy and safety of an IVT injection of TA with the less invasive posterior subtenon (PST) injection of TA. We test the hypothesis that both techniques have equal efficacy and safety.Patients and methodsThis is prospective randomized noninferiority trial. Totally, 34 eyes from 30 patients with diffuse center involving DME were randomized in a 1: 1 ratio to receive a TA injection by either method. Baseline evaluation included measurement of best-corrected visual acuity (BCVA) and intraocular pressure (IOP), fundus fluorescein angiography, and optical coherence tomography to measure central macular thickness (CMT) and evaluation of the crystalline lens. After the injection, patients were seen at 1 week, 1 month, 3 months, and 6 months and their BCVA, CMT, IOP, and change in these measures from baseline as well as other complications were recorded. A Mann–Whitney U-test was used to compare the mean of quantitative variables and a c2-test was used to compare qualitative variables between the two groups.ResultsAt baseline, both groups showed no statistically significant difference in age, sex, IOP, BCVA, and CMT. At 1, 3, and 6 months, both groups showed no statistically significant difference in the mean BCVA as well as change in BCVA from baseline. The average reduction of CMT was significantly higher only in the IVT group at 1 month (P = 0.03). The mean IOP and average IOP change from baseline were significantly higher in the IVT group than the PST group only at 3 months after injection (P = 0.02). Both groups showed a similar incidence of development of cataract (P = 1.0, c2).ConclusionIVT injection of TA is more effective than PST injection in improving CMT – that is, anatomical outcome. This is not, however, translated into a superior visual outcome. The risk of IOP elevation is also higher in IVT than PST injection. PST is a valid alternative to an IVT injection, especially from the functional perspective and when the risk of IOP elevation is significant.
      Citation: Journal of Current Medical Research and Practice 2017 2(2):141-149
      PubDate: Mon,6 Nov 2017
      DOI: 10.4103/JCMRP.JCMRP_29_16
      Issue No: Vol. 2, No. 2 (2017)
       
 
 
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