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Publisher: Medknow Publishers   (Total: 356 journals)

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Showing 1 - 200 of 356 Journals sorted alphabetically
Advanced Arab Academy of Audio-Vestibulogy J.     Open Access  
Advances in Human Biology     Open Access  
African J. for Infertility and Assisted Conception     Open Access  
African J. of Business Ethics     Open Access   (Followers: 7)
African J. of Medical and Health Sciences     Open Access  
African J. of Paediatric Surgery     Open Access   (Followers: 7, SJR: 0.269, h-index: 10)
African J. of Trauma     Open Access  
Ain-Shams J. of Anaesthesiology     Open Access   (Followers: 3)
Al-Azhar Assiut Medical J.     Open Access  
Al-Basar Intl. J. of Ophthalmology     Open Access  
Ancient Science of Life     Open Access   (Followers: 6)
Anesthesia : Essays and Researches     Open Access   (Followers: 7)
Annals of African Medicine     Open Access   (Followers: 1, SJR: 0.331, h-index: 15)
Annals of Bioanthropology     Open Access   (Followers: 2)
Annals of Cardiac Anaesthesia     Open Access   (Followers: 12, SJR: 0.408, h-index: 15)
Annals of Indian Academy of Neurology     Open Access   (Followers: 3, SJR: 0.308, h-index: 14)
Annals of Maxillofacial Surgery     Open Access   (Followers: 6)
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 5, SJR: 0.441, h-index: 10)
Annals of Saudi Medicine     Open Access   (SJR: 0.24, h-index: 29)
Annals of Thoracic Medicine     Open Access   (Followers: 4, SJR: 0.388, h-index: 19)
Annals of Tropical Medicine and Public Health     Open Access   (Followers: 15, SJR: 0.148, h-index: 5)
APOS Trends in Orthodontics     Open Access   (Followers: 1)
Arab J. of Interventional Radiology     Open Access  
Archives of Intl. Surgery     Open Access   (Followers: 9)
Archives of Medicine and Health Sciences     Open Access   (Followers: 2)
Archives of Pharmacy Practice     Open Access   (Followers: 4)
Asia Pacific J. of Clinical Trials : Nervous System Diseases     Open Access  
Asia-Pacific J. of Oncology Nursing     Open Access   (Followers: 3)
Asian J. of Andrology     Open Access   (Followers: 1, SJR: 0.879, h-index: 49)
Asian J. of Neurosurgery     Open Access   (Followers: 2)
Asian J. of Oncology     Open Access   (Followers: 1)
Asian J. of Transfusion Science     Open Access   (Followers: 1, SJR: 0.362, h-index: 10)
Astrocyte     Open Access  
Avicenna J. of Medicine     Open Access   (Followers: 1)
AYU : An international quarterly journal of research in Ayurveda     Open Access   (Followers: 6)
Benha Medical J.     Open Access  
BLDE University J. of Health Sciences     Open Access  
Brain Circulation     Open Access   (Followers: 1)
Bulletin of Faculty of Physical Therapy     Open Access  
Cancer Translational Medicine     Open Access   (Followers: 1)
CHRISMED J. of Health and Research     Open Access  
Clinical Dermatology Review     Open Access  
Clinical Trials in Degenerative Diseases     Open Access  
Clinical Trials in Orthopedic Disorders     Open Access  
Community Acquired Infection     Open Access  
Conservation and Society     Open Access   (Followers: 10, SJR: 0.82, h-index: 12)
Contemporary Clinical Dentistry     Open Access   (Followers: 4)
Current Medical Issues     Open Access  
CytoJ.     Open Access   (Followers: 2, SJR: 0.339, h-index: 19)
Delta J. of Ophthalmology     Open Access  
Dental Hypotheses     Open Access   (Followers: 3, SJR: 0.131, h-index: 4)
Dental Research J.     Open Access   (Followers: 9)
Dentistry and Medical Research     Open Access  
Digital Medicine     Open Access  
Drug Development and Therapeutics     Open Access  
Education for Health     Open Access   (Followers: 4, SJR: 0.205, h-index: 22)
Egyptian J. of Bronchology     Open Access  
Egyptian J. of Cardiothoracic Anesthesia     Open Access  
Egyptian J. of Cataract and Refractive Surgery     Open Access   (Followers: 1)
Egyptian J. of Dermatology and Venerology     Open Access  
Egyptian J. of Haematology     Open Access  
Egyptian J. of Internal Medicine     Open Access  
Egyptian J. of Neurology, Psychiatry and Neurosurgery     Open Access   (Followers: 1, SJR: 0.121, h-index: 3)
Egyptian J. of Obesity, Diabetes and Endocrinology     Open Access  
Egyptian J. of Otolaryngology     Open Access  
Egyptian J. of Psychiatry     Open Access   (Followers: 2)
Egyptian J. of Surgery     Open Access   (Followers: 1)
Egyptian Orthopaedic J.     Open Access  
Egyptian Pharmaceutical J.     Open Access  
Egyptian Retina J.     Open Access  
Egyptian Rheumatology and Rehabilitation     Open Access  
Endodontology     Open Access  
Endoscopic Ultrasound     Open Access   (SJR: 0.473, h-index: 8)
Environmental Disease     Open Access  
European J. of Dentistry     Open Access   (Followers: 2, SJR: 0.496, h-index: 11)
European J. of General Dentistry     Open Access   (Followers: 1)
European J. of Prosthodontics     Open Access   (Followers: 2)
European J. of Psychology and Educational Studies     Open Access   (Followers: 6)
Fertility Science and Research     Open Access  
Formosan J. of Surgery     Open Access   (SJR: 0.107, h-index: 5)
Genome Integrity     Open Access   (Followers: 4, SJR: 1.227, h-index: 12)
Global J. of Transfusion Medicine     Open Access  
Heart India     Open Access  
Heart Views     Open Access  
Hepatitis B Annual     Open Access   (Followers: 3)
IJS Short Reports     Open Access  
Indian Anaesthetists Forum     Open Access  
Indian Dermatology Online J.     Open Access   (Followers: 2)
Indian J. of Allergy, Asthma and Immunology     Open Access   (Followers: 1)
Indian J. of Anaesthesia     Open Access   (Followers: 7, SJR: 0.302, h-index: 13)
Indian J. of Burns     Open Access   (Followers: 1)
Indian J. of Cancer     Open Access   (SJR: 0.318, h-index: 26)
Indian J. of Cerebral Palsy     Open Access  
Indian J. of Community Medicine     Open Access   (Followers: 2, SJR: 0.618, h-index: 16)
Indian J. of Critical Care Medicine     Open Access   (Followers: 1, SJR: 0.307, h-index: 16)
Indian J. of Dental Research     Open Access   (Followers: 4, SJR: 0.243, h-index: 24)
Indian J. of Dental Sciences     Open Access  
Indian J. of Dentistry     Open Access   (Followers: 1)
Indian J. of Dermatology     Open Access   (Followers: 2, SJR: 0.448, h-index: 16)
Indian J. of Dermatology, Venereology and Leprology     Open Access   (Followers: 2, SJR: 0.563, h-index: 29)
Indian J. of Dermatopathology and Diagnostic Dermatology     Open Access  
Indian J. of Drugs in Dermatology     Open Access  
Indian J. of Endocrinology and Metabolism     Open Access   (Followers: 4)
Indian J. of Health Sciences     Open Access   (Followers: 1)
Indian J. of Medical and Paediatric Oncology     Open Access   (SJR: 0.292, h-index: 9)
Indian J. of Medical Microbiology     Open Access   (Followers: 1, SJR: 0.53, h-index: 34)
Indian J. of Medical Research     Open Access   (Followers: 4, SJR: 0.716, h-index: 60)
Indian J. of Medical Sciences     Open Access   (Followers: 2, SJR: 0.207, h-index: 31)
Indian J. of Multidisciplinary Dentistry     Open Access   (Followers: 1)
Indian J. of Nephrology     Open Access   (Followers: 1, SJR: 0.233, h-index: 12)
Indian J. of Nuclear Medicine     Open Access   (Followers: 2, SJR: 0.213, h-index: 5)
Indian J. of Occupational and Environmental Medicine     Open Access   (Followers: 4, SJR: 0.203, h-index: 13)
Indian J. of Ophthalmology     Open Access   (Followers: 4, SJR: 0.536, h-index: 34)
Indian J. of Oral Health and Research     Open Access  
Indian J. of Oral Sciences     Open Access   (Followers: 1)
Indian J. of Orthopaedics     Open Access   (Followers: 9, SJR: 0.393, h-index: 15)
Indian J. of Otology     Open Access   (Followers: 1, SJR: 0.218, h-index: 5)
Indian J. of Paediatric Dermatology     Open Access   (Followers: 1)
Indian J. of Pain     Open Access   (Followers: 1)
Indian J. of Palliative Care     Open Access   (Followers: 5, SJR: 0.35, h-index: 12)
Indian J. of Pathology and Microbiology     Open Access   (Followers: 1, SJR: 0.285, h-index: 22)
Indian J. of Pharmacology     Open Access   (SJR: 0.347, h-index: 44)
Indian J. of Plastic Surgery     Open Access   (Followers: 12, SJR: 0.303, h-index: 13)
Indian J. of Psychiatry     Open Access   (Followers: 3, SJR: 0.496, h-index: 15)
Indian J. of Psychological Medicine     Open Access   (Followers: 1, SJR: 0.344, h-index: 9)
Indian J. of Public Health     Open Access   (Followers: 1, SJR: 0.444, h-index: 17)
Indian J. of Radiology and Imaging     Open Access   (Followers: 4, SJR: 0.253, h-index: 14)
Indian J. of Research in Homoeopathy     Open Access  
Indian J. of Rheumatology     Open Access   (SJR: 0.169, h-index: 7)
Indian J. of Sexually Transmitted Diseases and AIDS     Open Access   (Followers: 2, SJR: 0.313, h-index: 9)
Indian J. of Social Psychiatry     Open Access   (Followers: 2)
Indian J. of Urology     Open Access   (Followers: 3, SJR: 0.366, h-index: 16)
Indian J. of Vascular and Endovascular Surgery     Open Access   (Followers: 2)
Industrial Psychiatry J.     Open Access   (Followers: 2)
Intl. J. of Academic Medicine     Open Access  
Intl. J. of Advanced Medical and Health Research     Open Access  
Intl. J. of Applied and Basic Medical Research     Open Access  
Intl. J. of Clinical and Experimental Physiology     Open Access   (Followers: 1)
Intl. J. of Critical Illness and Injury Science     Open Access  
Intl. J. of Educational and Psychological Researches     Open Access   (Followers: 2)
Intl. J. of Environmental Health Engineering     Open Access   (Followers: 1)
Intl. J. of Forensic Odontology     Open Access   (Followers: 1)
Intl. J. of Green Pharmacy     Open Access   (Followers: 4, SJR: 0.229, h-index: 13)
Intl. J. of Health & Allied Sciences     Open Access   (Followers: 1)
Intl. J. of Health System and Disaster Management     Open Access   (Followers: 2)
Intl. J. of Heart Rhythm     Open Access  
Intl. J. of Medicine and Public Health     Open Access   (Followers: 7)
Intl. J. of Mycobacteriology     Open Access   (SJR: 0.239, h-index: 4)
Intl. J. of Noncommunicable Diseases     Open Access  
Intl. J. of Nutrition, Pharmacology, Neurological Diseases     Open Access   (Followers: 4)
Intl. J. of Oral Health Sciences     Open Access   (Followers: 1)
Intl. J. of Orthodontic Rehabilitation     Open Access  
Intl. J. of Pedodontic Rehabilitation     Open Access  
Intl. J. of Pharmaceutical Investigation     Open Access   (Followers: 1)
Intl. J. of Preventive Medicine     Open Access   (Followers: 1, SJR: 0.523, h-index: 15)
Intl. J. of Shoulder Surgery     Open Access   (Followers: 6, SJR: 0.611, h-index: 9)
Intl. J. of Trichology     Open Access   (SJR: 0.37, h-index: 10)
Intl. J. of Yoga     Open Access   (Followers: 15)
Intl. J. of Yoga : Philosophy, Psychology and Parapsychology     Open Access   (Followers: 6)
Iranian J. of Nursing and Midwifery Research     Open Access   (Followers: 2)
Iraqi J. of Hematology     Open Access  
J. of Academy of Medical Sciences     Open Access  
J. of Advanced Pharmaceutical Technology & Research     Open Access   (Followers: 4, SJR: 0.427, h-index: 15)
J. of Anaesthesiology Clinical Pharmacology     Open Access   (Followers: 8, SJR: 0.416, h-index: 14)
J. of Applied Hematology     Open Access  
J. of Association of Chest Physicians     Open Access   (Followers: 2)
J. of Basic and Clinical Reproductive Sciences     Open Access   (Followers: 1)
J. of Cancer Research and Therapeutics     Open Access   (Followers: 4, SJR: 0.359, h-index: 21)
J. of Carcinogenesis     Open Access   (Followers: 1, SJR: 1.152, h-index: 26)
J. of Cardiothoracic Trauma     Open Access  
J. of Cardiovascular Disease Research     Open Access   (Followers: 3, SJR: 0.351, h-index: 13)
J. of Cardiovascular Echography     Open Access   (SJR: 0.134, h-index: 2)
J. of Cleft Lip Palate and Craniofacial Anomalies     Open Access   (Followers: 2)
J. of Clinical and Preventive Cardiology     Open Access  
J. of Clinical Imaging Science     Open Access   (Followers: 1, SJR: 0.277, h-index: 8)
J. of Clinical Neonatology     Open Access   (Followers: 1)
J. of Clinical Ophthalmology and Research     Open Access   (Followers: 1)
J. of Clinical Sciences     Open Access  
J. of Conservative Dentistry     Open Access   (Followers: 4, SJR: 0.532, h-index: 10)
J. of Craniovertebral Junction and Spine     Open Access   (Followers: 4, SJR: 0.199, h-index: 9)
J. of Current Medical Research and Practice     Open Access  
J. of Current Research in Scientific Medicine     Open Access  
J. of Cutaneous and Aesthetic Surgery     Open Access   (Followers: 1)
J. of Cytology     Open Access   (Followers: 1, SJR: 0.274, h-index: 9)
J. of Dental and Allied Sciences     Open Access   (Followers: 1)
J. of Dental Implants     Open Access   (Followers: 7)
J. of Dental Lasers     Open Access   (Followers: 2)
J. of Dental Research and Review     Open Access   (Followers: 1)
J. of Digestive Endoscopy     Open Access   (Followers: 3)
J. of Dr. NTR University of Health Sciences     Open Access  
J. of Earth, Environment and Health Sciences     Open Access   (Followers: 1)
J. of Education and Ethics in Dentistry     Open Access   (Followers: 5)
J. of Education and Health Promotion     Open Access   (Followers: 5)
J. of Emergencies, Trauma and Shock     Open Access   (Followers: 8, SJR: 0.353, h-index: 14)
J. of Engineering and Technology     Open Access   (Followers: 6)
J. of Experimental and Clinical Anatomy     Open Access   (Followers: 2)
J. of Family and Community Medicine     Open Access  
J. of Family Medicine and Primary Care     Open Access   (Followers: 8)

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Journal Cover BLDE University Journal of Health Sciences
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  This is an Open Access Journal Open Access journal
   ISSN (Print) 2468-838X - ISSN (Online) 2456-1975
   Published by Medknow Publishers Homepage  [356 journals]
  • The hot button issue of salt-sensitive hypertension

    • Authors: Dewan S. A. Majid, L Gabriel Navar
      Pages: 65 - 68
      Abstract: Dewan S. A. Majid, L Gabriel Navar
      BLDE University Journal of Health Sciences 2016 1(2):65-68

      Citation: BLDE University Journal of Health Sciences 2016 1(2):65-68
      PubDate: Mon,19 Dec 2016
      DOI: 10.4103/2468-838X.196077
      Issue No: Vol. 1, No. 2 (2016)
       
  • Challenges for application of realgar: A critical review

    • Authors: Vineet Sharma, Narendra Kumar Singh, Dev Nath Singh Gautam
      Pages: 69 - 72
      Abstract: Vineet Sharma, Narendra Kumar Singh, Dev Nath Singh Gautam
      BLDE University Journal of Health Sciences 2016 1(2):69-72
      Realgar has been not only well-known poisons but also used as healing agent. Realgar has long been used in traditional medicines for different diseases; so far arsenic can be extremely toxic and carcinogenic. In Ayurvedic and Chinese traditional medicines arsenic usually comes from conscious addition for healing purposes, mostly in the form of mineral arsenicals with orpiment (As2S3), realgar (As4S4), and arsenic trioxide (As2O3). Pharmacological studies revealed that realgar is effective against in different cancer cell line. However, it has been critically limited clinical applications because of its many disadvantages, for example, low solubility in water, high toxicity, poor gastrointestinal absorption, and bioavailability. This review evaluates the toxicology, bioaccessibility, and pharmacology of the realgar used in Ayurvedic and Chinese traditional medicines. In recent times, numerous types of realgar nanoparticles (NPs) have been developed due to insolubility of realgar in water and different media. Most of the NPs of realgar possess the exclusive optical qualities of quantum dots. The pharmacological activities and bioavailability of realgar NPs are much more partial by their sizes, building realgar an exciting biomedical and pharmaceutical research applicant.
      Citation: BLDE University Journal of Health Sciences 2016 1(2):69-72
      PubDate: Mon,19 Dec 2016
      DOI: 10.4103/2468-838X.196079
      Issue No: Vol. 1, No. 2 (2016)
       
  • A unique, intuitive, creative, innovative, bold scientist in endless quest
           of the truth and a giant in high-altitude medicine: Prof. Dr. Gustavo
           Zubieta-Castillo, "The Parvatha Guru" (May 20, 1926-September 17, 2015)

    • Authors: Gustavo Zubieta-Calleja, Natalia Zubieta-De Urioste
      Pages: 73 - 80
      Abstract: Gustavo Zubieta-Calleja, Natalia Zubieta-De Urioste
      BLDE University Journal of Health Sciences 2016 1(2):73-80
      Professor Gustavo Zubieta-Castillo - The Mountain Guru, Bolivian visionary, loved art and science. He was a word class pioneer and defender of life and medicine at high altitude. In 1964, after his observations of the perfused heart in dogs, he affirmed that the hearts of high-altitude residents are much more resistant to hypoxia than those at sea level. He clarified misconceptions about lung diseases at high altitude, which were improperly termed "loss of adaptation." His original and unique views on what was called chronic mountain sickness (CMS), a term he proposed be discarded and be rather expressed as polyerythrocythemia (as a more precise symptomatic description of multiple pathologies in the hypoxic environment of high altitude). He created the "triple hypoxia syndrome," an essential description to explain the momentary decrease of PaO 2 in polyerythrocythemic patients. His concepts of hypoxia gave rise to the formulation of the high-altitude adaptation formula. On his obituary, legendary respiratory physiologist Prof. John B. West stated, "He was a remarkable man and our discipline has lost a giant." Renowned Environmental scientist Prof. Thuppil Venkatesh, a long-time friend of Prof. Gustavo Sr., stated, "We lost one of the most valuable and precious personalities… a great loss to the world scientific community." Prof. Gustavo's son Prof. Dr. Gustavo Zubieta Calleja is also a renowned pulmonologist like his legendary father and keeping his illustrious father's legacy with pride and honor at his "High Altitude Pulmonary and Pathology Institute," La Paz, Bolivia.
      Citation: BLDE University Journal of Health Sciences 2016 1(2):73-80
      PubDate: Mon,19 Dec 2016
      DOI: 10.4103/2468-838X.196081
      Issue No: Vol. 1, No. 2 (2016)
       
  • Impact of fat mass distribution body shapes on muscles strength and the
           joints pain

    • Authors: Zerf Mohammed, Bengoua Ali, Mokkedes Moulay Idris, Hakim Hamzaoui, Lakhdar Messaliti
      Pages: 81 - 88
      Abstract: Zerf Mohammed, Bengoua Ali, Mokkedes Moulay Idris, Hakim Hamzaoui, Lakhdar Messaliti
      BLDE University Journal of Health Sciences 2016 1(2):81-88
      Our study focuses on fat mass distribution body shapes type as measured to determine their effect on skeletal muscle strengthening lumbar extensors (upper and lower limbs) where our background confirms that every girl has a natural body type of rectangle, apple, pear, or hourglass. It is good for her to know which type of body shape she is, so she can learn what exercises to do, whereas similar studies suggest that it is much better to challenge weight problems with exercise and dietary measures before resorting to figure shaping. For this purpose, our study was carried out with a total of thirty students, females listed in the Institute of Physical Education and Sport, University of Mostaganem, aged between 20 and 23 years; their homogeneity was based on age, sex, and academic specialty, classified based on the body mass index (BMI) into two groups (normal and overweight) and based on their body shape's type into three groups (9 pear shape, 10 rectangle shape, and 11 hourglass shape) as a protocol experimental to examine the impact of fat mass distribution body shapes type on lumbar extensor strength. Based on our data analysis, we confirm that the pear and the rectangle shape affect the strength lumbar extensors due to body weight distribution which increases the risks relating to the skeletal muscles. Weight gain is a factor contributing to the weakness of skeletal muscles. However, the body shape explains the anomalies of the distribution of fat mass and BMI risk observed in our sample in the lower and upper part of the body recorded by the values of Killy test and endurance of trunk, the case of the pear and the rectangle shape back pain, which are consisting in excess of the body fat distributed in comparison with less percentage of muscle mass. Whereas this difference can affect the pelvic position.
      Citation: BLDE University Journal of Health Sciences 2016 1(2):81-88
      PubDate: Mon,19 Dec 2016
      DOI: 10.4103/2468-838X.196084
      Issue No: Vol. 1, No. 2 (2016)
       
  • Green-synthesized silver nanoparticles kill virulent multidrug-resistant
           Pseudomonas aeruginosa strains: A mechanistic study

    • Authors: Balaram Das, Sandeep Kumar Dash, Debasis Mandal, Jaydeep Adhikary, Sourav Chattopadhyay, Satyajit Tripathy, Aditi Dey, Subhankar Manna, Sankar Kumar Dey, Debasis Das, Somenath Roy
      Pages: 89 - 101
      Abstract: Balaram Das, Sandeep Kumar Dash, Debasis Mandal, Jaydeep Adhikary, Sourav Chattopadhyay, Satyajit Tripathy, Aditi Dey, Subhankar Manna, Sankar Kumar Dey, Debasis Das, Somenath Roy
      BLDE University Journal of Health Sciences 2016 1(2):89-101
      Background: Due to abuse and improper prescribing policy of antibiotics, the antibiotics resistance were remarkably increased in Pseudomonas aeruginosa, so there are urgently need to develop a new kind of antimicrobial to treat Pseudomonas aeruginosa infection. Biosynthesized silver nanoparticles (Ag NPs) have showed its interesting impact against bacterial infection drawn researchers to green nanotechnology. Aims: The study was conducted to evaluate the antibacterial activity of AgNPs against multi drug resistant P. aeruginosa isolated from urine sample of UTI patients. Methods: 126 UTI patent's urine samples were included in the study. P. aeruginosa strains were isolated, identify, antimicrobial susceptibility, drug resistance mechanisms were done as per routine laboratory protocol. The antimicrobial activity and mechanisms of the killing of Ag NPs were studied. Results: From this study, it was revealed that 25 (19.84%) isolates were multi drug resistant Pseudomonas aeruginosa. Green synthesized Ag NPs successfully destroyed the multi drug resistant strains via ROS generation and membrane damage. The prevalence of multidrug resistance is increased worldwide and there are urgently need another option to control the multidrug resistant strains. Conclusion: The findings of the study suggested that Ag NPs might be used to treat the multi drug resistant Pseudomonas aeruginosa.
      Citation: BLDE University Journal of Health Sciences 2016 1(2):89-101
      PubDate: Mon,19 Dec 2016
      DOI: 10.4103/2468-838X.196087
      Issue No: Vol. 1, No. 2 (2016)
       
  • Immunohistochemical study of p53, Ki-67, epidermal growth factor receptor,
           and sex-determining region Y-box 2 in squamous cell carcinoma of tongue

    • Authors: Pallavi D Bhayekar, Vandana L Gaopande, Avinash R Joshi, Amruta B Jadhav
      Pages: 102 - 107
      Abstract: Pallavi D Bhayekar, Vandana L Gaopande, Avinash R Joshi, Amruta B Jadhav
      BLDE University Journal of Health Sciences 2016 1(2):102-107
      Objective: Tongue cancer (TC) is one of the most common oral cancers. Prognostic evaluation of this tumor includes histologic grade and TNM stage. In this study, we evaluated the expression of p53, Ki-67, epidermal growth factor receptor (EGFR), and sex-determining region Y-box 2 (SOX2) and correlated it with the clinicopathologic variables to assess their potential for use as prognostic markers. We compared the p53 positive and negative group. Design: A retrospective and prospective study with 45 cases of biopsy proven TC which were studied for the expression of p53, Ki-67, EGFR, and SOX2. The results were correlated with known clinicopathologic variables using Chi-square test. The p53 positive and negative groups were compared. Materials and Methods: Archieved blocks of biopsy proven TC were retrieved. Using 4 micron sections of the blockes immunostaining for p53, Ki67, EGFR and SOX2 was done. Results: P53 expression was 68.9%, Ki-67 was 88.9%, EGFR was 48.9%, and SOX2 was 35.6%. Expression of p53 and Ki-67 did not show any correlation with any of the clinicopathologic variables. There was a statistically significant association between EGFR expression and lymph node (LN) positivity (P = 0.001). Stage of tumor and SOX2 positivity showed a significant correlation (P = 0.03). The comparison of p53 positive and negative groups did not reveal a significant difference. Conclusion: p53-negative TC is not significantly different from the p53-positive TC at presentation. The absence of mutant p53 in more than 30% TC points toward the possible etiological role of human papillomavirus in TC. Larger studies are needed to evaluate the possible use of EGFR for prediction of LN metastasis and SOX2 as a prognostic marker.
      Citation: BLDE University Journal of Health Sciences 2016 1(2):102-107
      PubDate: Mon,19 Dec 2016
      DOI: 10.4103/2468-838X.196089
      Issue No: Vol. 1, No. 2 (2016)
       
  • Effect of herbo-mineral formulation (Shilajatu Rasayana) in
           letrozole-induced polycystic ovarian syndrome

    • Authors: Vanitha Hosur Kumari, Revanasiddappa S Sarashetti, Kashinath S Hadimur, Kasturi A Patil
      Pages: 108 - 112
      Abstract: Vanitha Hosur Kumari, Revanasiddappa S Sarashetti, Kashinath S Hadimur, Kasturi A Patil
      BLDE University Journal of Health Sciences 2016 1(2):108-112
      The major cause of female infertility in recent years is polycystic ovarian syndrome commonly called as PCOS, compared to yonivyapath (disorders of female reproductive system) described in Ayurveda. Shilajatu Rasayana herbo-mineral preparation mentioned in "Rasendra Chudamani" indicated in yonyaamaya (disorders of female reproductive system), gulma (tumors), meha (hyperinsulinemia), pandu (anemia), etc. is expected to contribute positive and better result in letrozole-induced PCOS, considering the previous analytical and experimental studies. Letrozole, Shilajatu Rasayana, clomiphene citrate, ghee, and female albino rats formed the materials for the study. Totally thirty female rats were initially induced to develop PCOS by injecting letrozole. The induction of PCOS in rats was checked through vaginal smear analysis and further confirmed by hormonal assay. PCOS-induced rats were treated with clomiphene citrate (standard), Shilajatu Rasayana (test drug), and ghee (control). Ovarian and uterine weight, hormonal assay, and histomorphometric changes were observed and recorded. Shilajatu Rasayana has shown a significant result in letrozole-induced PCOS by regulating hormones, reduction of cystic follicles, maturation of ovarian follicles, and decreasing the increased ovarian and uterine weight.
      Citation: BLDE University Journal of Health Sciences 2016 1(2):108-112
      PubDate: Mon,19 Dec 2016
      DOI: 10.4103/2468-838X.196093
      Issue No: Vol. 1, No. 2 (2016)
       
  • Evaluation of endophytic fractions of Boerhaavia diffusa Linn. roots for
           hepatoprotective activity in rats

    • Authors: Smita D Madagundi, Poonam Kothli, Prasanna V Habbu, Venkatrao H Kulkarni
      Pages: 113 - 119
      Abstract: Smita D Madagundi, Poonam Kothli, Prasanna V Habbu, Venkatrao H Kulkarni
      BLDE University Journal of Health Sciences 2016 1(2):113-119
      Objectives: Endophytes are major originators of new bioactive compounds with fascinating pharmacological activities. In this study, a perusal was done for isolation, characterization, and screening of endophytic bacteria of Boerhaavia diffusa Linn (BDEF) root for antioxidant and hepatoprotective activities. Methods: BDEF was isolated from the roots and grown in nutrient agar media aseptically. The grown bacteria was further fermented in nutrient broth and extracted using chloroform (CBD) and ethyl acetate (EABD). CBD and EABD were assayed for free radical scavenging properties against 2, 2 diphenyl 1 picryl hydrazyl (DPPH), hydroxyl radical, and reducing power. Findings: The highest inhibition was exhibited in EABD with IC50 level of 22.86 μg/ml for DPPH and 82.78 μg/ml for hydroxyl radical, respectively. Further, CBD and EABD (100 and 200 mg/kg) were evaluated for antihepatotoxic activity against CCl4 induced hepatotoxicity. The results revealed that CBD and EABD (200 mg/kg p.o.) restored the biochemical parameters, against CCl4 induced hepatotoxicity to the normal values. The altered lipid peroxidation, superoxide dismutase, and catalase levels were also restored by EABD (200 mg/kg p.o.). BDEF was studied for rDNA sequencing by polymerase chain reaction technique. The endophytic bacterium was identified as Bacillus cereus based on its morphological and molecular characterization. Conclusions: CBD and EABD fractions have exhibited antioxidant and hepatoprotective activity.
      Citation: BLDE University Journal of Health Sciences 2016 1(2):113-119
      PubDate: Mon,19 Dec 2016
      DOI: 10.4103/2468-838X.196095
      Issue No: Vol. 1, No. 2 (2016)
       
  • Shelf life evaluation of Shirishavaleha: A preliminary study

    • Authors: Harmeet Kaur, Galib Ruknuddin, Pradeep Kumar Prajapati
      Pages: 120 - 124
      Abstract: Harmeet Kaur, Galib Ruknuddin, Pradeep Kumar Prajapati
      BLDE University Journal of Health Sciences 2016 1(2):120-124
      Context: Shelf life of the drug can be considered up to the period it gets deteriorated and does not get any alteration in its physicochemical state. Every product has definite shelf life, which depends on various physical, chemical, environmental, and biological factors. Ancient seers have clarified shelf life of various compound formulations. However, there is a need to revalidate and ascertain the shelf life of individual formulations by following parameters prevalent in respective scenario. Aim: To evaluate shelf life of Shirishavaleha prepared in the presence of water (SW) and Kanji (SK) as liquid media through accelerated stability study. Subjects and Methods: Physicochemical parameters were measured at 40°C ± 2°C temperature and 75% ±5% relative humidity. Analysis was repeated at intervals of 1, 3, and 6 months, and average 10% degradation of both the test drug samples was calculated and extrapolated to find the shelf life. Results: The sample prepared in the presence of Kanji (SK) showed more extractive values and sugar contents and found to have longer shelf life (2.6 years) than SW (1.4 years). Conclusion: Shirishavaleha prepared with Kanji (SK) is comparatively more stable than the sample prepared with water (SW).
      Citation: BLDE University Journal of Health Sciences 2016 1(2):120-124
      PubDate: Mon,19 Dec 2016
      DOI: 10.4103/2468-838X.196099
      Issue No: Vol. 1, No. 2 (2016)
       
  • Clinicopathological study of rare invasive epithelial tumors of breast: An
           institutional study

    • Authors: Karthik Kasireddy, K Manjula, C. S. B. R. Prasad
      Pages: 125 - 127
      Abstract: Karthik Kasireddy, K Manjula, C. S. B. R. Prasad
      BLDE University Journal of Health Sciences 2016 1(2):125-127
      Introduction: Invasive breast cancer (BC) is the most common carcinoma in women. It accounts for 22% of all female cancers. Most tumors are derived from mammary duct epithelium, and up to 75% of BCs are ductal carcinomas. The second most common tumor is invasive lobular carcinoma. However, there are many variants which are less common but well defined by the World Health Organization classification. They comprise
      Citation: BLDE University Journal of Health Sciences 2016 1(2):125-127
      PubDate: Mon,19 Dec 2016
      DOI: 10.4103/2468-838X.196102
      Issue No: Vol. 1, No. 2 (2016)
       
  • Intimate partner violence among college students without disabilities and
           college students with disabilities: An exploratory study

    • Authors: Miranda Sue Terry
      Pages: 128 - 132
      Abstract: Miranda Sue Terry
      BLDE University Journal of Health Sciences 2016 1(2):128-132
      Aims: The purpose of this exploratory research study was to examine the gender differences and role of disability among college students experienced intimate partner violence. The research project sought to address two questions: (1) are there gender differences? and (2) are there differences between people with disabilities and people without disabilities? Setting and Design: A large university in the Midwest, United States of America. A quantitative research design was used. Materials and Methods: This research project used a quantitative research design using a packet consisting of abuse screening surveys: Abuse Assessment Screen-Disability (AAS-D) and Revised Conflict Tactics Scale (CTS2). Statistical analysis used: The quantitative surveys were analyzed using IBM SPSS version 22.0. Data input used a double entry method where the investigator entered the data into one SPSS sheet, an assistant entered the data into a separate SPSS sheet, and then the sheets were merged to check for discrepancies. The hypotheses were addressed using inferential statistics, such as Likelihood Ratio. Results: The results of this study indicate that there were no statistical differences between the rates at which men and women experience abuse. These results are not similar to previous literature. Other findings of this study indicate that people with disabilities experience similar rates of abuse as people without disabilities. These findings are similar to previous literature. Conclusions: Due to the small number of participants with disabilities, the statistical findings showed trends. A larger scale study would need to be conducted to draw any conclusions statistically. These trends should provide a shift in society and its views on who is affected by intimate partner violence and ensure everyone who is experiencing abuse has options to leave the relationship and has resources available and accessible to them.
      Citation: BLDE University Journal of Health Sciences 2016 1(2):128-132
      PubDate: Mon,19 Dec 2016
      DOI: 10.4103/2468-838X.196104
      Issue No: Vol. 1, No. 2 (2016)
       
  • Pharmaceutico-physicochemical validation of Mamajjaka Ghana tablet, a
           potent antidiabetic medicine

    • Authors: Ashish Verma, Hetal Janani, Shobhnath Yadav, Sanjay Ghimire, BJ Patgiri, PK Prajapati
      Pages: 133 - 138
      Abstract: Ashish Verma, Hetal Janani, Shobhnath Yadav, Sanjay Ghimire, BJ Patgiri, PK Prajapati
      BLDE University Journal of Health Sciences 2016 1(2):133-138
      Background: Mamajjaka Ghana Vati is a well-recognized herbal medicine for the treatment of Madhumeha. Instead of its attribute in Madhumeha, it was also therapeutically indicated for antipyretic, anthelmintic, hepatoprotective, and anti-inflammatory activities. Aims and Objective: The objective of the present study was to evaluate the significance of large-scale production of Mamajjaka Ghana tablet and its quality control aspect with a view of its wide range of applicability in therapeutics and ayurvedic pharmaceutical industry. Materials ad Methods: Mamajjaka Ghana tablet was prepared in four batches and the findings were scientifically recorded. In this analytical study, organoleptic and physicochemical evaluations of Mamajjaka decoction, solid aqueous extract (Ghana), and tablet were carried out. Results and Discussion: An average of 38.25 h were required for the preparation of Mamajjaka decoction. The average temperature maintained during the process was 95-100°C. The average yield of decoction was 168.75 L in all the four batches. An average of 11.67 kg of solid aqueous extract (Ghana) was obtained. A total of 46.68 kg of Ghana was obtained from all the four batches. An average of 97.93% of Mamajjaka Ghana tablet was obtained. Conclusion: The data pertaining to large-scale production will be useful for ayurvedic pharmaceutical industry populace to maintain quality, uniformity of dosage, and to sustain the batch-to-batch variation during various pharmaceutical operations, and thus the whole process is validated for 65.28 kg of Mamajjaka Ghana tablet .
      Citation: BLDE University Journal of Health Sciences 2016 1(2):133-138
      PubDate: Mon,19 Dec 2016
      DOI: 10.4103/2468-838X.196106
      Issue No: Vol. 1, No. 2 (2016)
       
  • The 14th Inter-medical School Physiology Quiz: Observations of common
           errors in the written test among students of 81 medical schools from 24
           countries

    • Authors: Hwee-Ming Cheng, See-Ziau Hoe
      Pages: 139 - 142
      Abstract: Hwee-Ming Cheng, See-Ziau Hoe
      BLDE University Journal of Health Sciences 2016 1(2):139-142
      The 14th Inter-medical School Physiology Quiz (IMSPQ) competition had 81 medical schools from 24 countries. Analyses of the written responses at the 14th IMSPQ from a total of 334 students provide a useful teaching and learning insights. These observations, highlighted here, were gleaned from (i) the questions with most correct answers, (ii) the most unanswered questions, and (iii) the most wrongly answered questions. The IMSPQ is a unique annual physiology event that provides a global sampling of students' appreciation and understanding of core concepts in physiology.
      Citation: BLDE University Journal of Health Sciences 2016 1(2):139-142
      PubDate: Mon,19 Dec 2016
      DOI: 10.4103/2468-838X.196107
      Issue No: Vol. 1, No. 2 (2016)
       
  • Double profunda brachii artery

    • Authors: Gavishiddappa A Hadimani, Jyoti V Hadimani, Ishwar B Bagoji, Shardha Bai Rathod, Balappa M Bannur
      Pages: 143 - 144
      Abstract: Gavishiddappa A Hadimani, Jyoti V Hadimani, Ishwar B Bagoji, Shardha Bai Rathod, Balappa M Bannur
      BLDE University Journal of Health Sciences 2016 1(2):143-144
      Brachial artery (BA) is a continuation of the axillary artery at the lower border of teres major. In the cubital fossa, BA divides into radial artery and ulnar artery as terminal branches. Large branch given from the BA in the upper part is profunda brachii artery. In the present case, we noticed double profunda brachii that arises from the BA. They are profunda brachii artery 1 and profunda brachii artery 2. Profunda brachii artery 1 arises in the proximal part of the BA and profunda brachii artery 2 arises distal to the profunda brachii artery 1. Both the arteries run inferolaterally in the spiral groove along with radial nerve. Variations of profunda brachii artery are important during harvesting of the lateral arm flaps and may lead to inadvertent injury during percutaneous arterial catheterization or injection of drugs.
      Citation: BLDE University Journal of Health Sciences 2016 1(2):143-144
      PubDate: Mon,19 Dec 2016
      DOI: 10.4103/2468-838X.196109
      Issue No: Vol. 1, No. 2 (2016)
       
  • Is mental health at risk among opioid dependent patients?

    • Authors: Radha Saini, Daljeet Kaur Saini, Colonel Manoj Bhatt, Preety Alagh
      Pages: 145 - 146
      Abstract: Radha Saini, Daljeet Kaur Saini, Colonel Manoj Bhatt, Preety Alagh
      BLDE University Journal of Health Sciences 2016 1(2):145-146

      Citation: BLDE University Journal of Health Sciences 2016 1(2):145-146
      PubDate: Mon,19 Dec 2016
      DOI: 10.4103/2468-838X.196110
      Issue No: Vol. 1, No. 2 (2016)
       
  • Oral verruca vulgaris

    • Authors: Karthik Shunmugavelu, Parthipan Gopalakrishnan
      Pages: 147 - 147
      Abstract: Karthik Shunmugavelu, Parthipan Gopalakrishnan
      BLDE University Journal of Health Sciences 2016 1(2):147-147

      Citation: BLDE University Journal of Health Sciences 2016 1(2):147-147
      PubDate: Mon,19 Dec 2016
      DOI: 10.4103/2468-838X.196111
      Issue No: Vol. 1, No. 2 (2016)
       
 
 
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