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Publisher: Medknow Publishers   (Total: 355 journals)

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Showing 1 - 200 of 355 Journals sorted alphabetically
Advanced Arab Academy of Audio-Vestibulogy J.     Open Access  
Advances in Human Biology     Open Access   (Followers: 2)
African J. for Infertility and Assisted Conception     Open Access  
African J. of Business Ethics     Open Access   (Followers: 6)
African J. of Medical and Health Sciences     Open Access   (Followers: 2)
African J. of Paediatric Surgery     Open Access   (Followers: 7, SJR: 0.269, h-index: 10)
African J. of Trauma     Open Access  
Ain-Shams J. of Anaesthesiology     Open Access   (Followers: 3)
Al-Azhar Assiut Medical J.     Open Access  
Al-Basar Intl. J. of Ophthalmology     Open Access   (Followers: 1)
Ancient Science of Life     Open Access   (Followers: 5)
Anesthesia : Essays and Researches     Open Access   (Followers: 9)
Annals of African Medicine     Open Access   (Followers: 1, SJR: 0.331, h-index: 15)
Annals of Bioanthropology     Open Access   (Followers: 4)
Annals of Cardiac Anaesthesia     Open Access   (Followers: 14, SJR: 0.408, h-index: 15)
Annals of Indian Academy of Neurology     Open Access   (Followers: 3, SJR: 0.308, h-index: 14)
Annals of Maxillofacial Surgery     Open Access   (Followers: 6)
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 7, SJR: 0.441, h-index: 10)
Annals of Saudi Medicine     Open Access   (SJR: 0.24, h-index: 29)
Annals of Thoracic Medicine     Open Access   (Followers: 5, SJR: 0.388, h-index: 19)
Annals of Tropical Medicine and Public Health     Open Access   (Followers: 12, SJR: 0.148, h-index: 5)
APOS Trends in Orthodontics     Open Access   (Followers: 1)
Arab J. of Interventional Radiology     Open Access  
Archives of Intl. Surgery     Open Access   (Followers: 10)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Archives of Pharmacy Practice     Open Access   (Followers: 6)
Asia Pacific J. of Clinical Trials : Nervous System Diseases     Open Access  
Asia-Pacific J. of Oncology Nursing     Open Access   (Followers: 4)
Asian J. of Andrology     Open Access   (Followers: 1, SJR: 0.879, h-index: 49)
Asian J. of Neurosurgery     Open Access   (Followers: 2)
Asian J. of Oncology     Open Access   (Followers: 1)
Asian J. of Transfusion Science     Open Access   (Followers: 1, SJR: 0.362, h-index: 10)
Astrocyte     Open Access  
Avicenna J. of Medicine     Open Access   (Followers: 1)
AYU : An international quarterly journal of research in Ayurveda     Open Access   (Followers: 6)
Benha Medical J.     Open Access  
BLDE University J. of Health Sciences     Open Access  
Brain Circulation     Open Access  
Bulletin of Faculty of Physical Therapy     Open Access   (Followers: 1)
Cancer Translational Medicine     Open Access   (Followers: 2)
CHRISMED J. of Health and Research     Open Access  
Clinical Dermatology Review     Open Access   (Followers: 2)
Clinical Trials in Degenerative Diseases     Open Access  
Clinical Trials in Orthopedic Disorders     Open Access  
Community Acquired Infection     Open Access  
Conservation and Society     Open Access   (Followers: 10, SJR: 0.82, h-index: 12)
Contemporary Clinical Dentistry     Open Access   (Followers: 4)
Current Medical Issues     Open Access   (Followers: 1)
CytoJ.     Open Access   (Followers: 2, SJR: 0.339, h-index: 19)
Delta J. of Ophthalmology     Open Access  
Dental Hypotheses     Open Access   (Followers: 3, SJR: 0.131, h-index: 4)
Dental Research J.     Open Access   (Followers: 11)
Dentistry and Medical Research     Open Access  
Digital Medicine     Open Access  
Drug Development and Therapeutics     Open Access  
Education for Health     Open Access   (Followers: 6, SJR: 0.205, h-index: 22)
Egyptian J. of Bronchology     Open Access  
Egyptian J. of Cardiothoracic Anesthesia     Open Access  
Egyptian J. of Cataract and Refractive Surgery     Open Access   (Followers: 1)
Egyptian J. of Dermatology and Venerology     Open Access   (Followers: 1)
Egyptian J. of Haematology     Open Access   (Followers: 1)
Egyptian J. of Internal Medicine     Open Access   (Followers: 1)
Egyptian J. of Neurology, Psychiatry and Neurosurgery     Open Access   (Followers: 1, SJR: 0.121, h-index: 3)
Egyptian J. of Obesity, Diabetes and Endocrinology     Open Access  
Egyptian J. of Otolaryngology     Open Access   (Followers: 2)
Egyptian J. of Psychiatry     Open Access   (Followers: 2)
Egyptian J. of Surgery     Open Access   (Followers: 1)
Egyptian Orthopaedic J.     Open Access   (Followers: 1)
Egyptian Pharmaceutical J.     Open Access  
Egyptian Retina J.     Open Access  
Egyptian Rheumatology and Rehabilitation     Open Access  
Endodontology     Open Access  
Endoscopic Ultrasound     Open Access   (SJR: 0.473, h-index: 8)
Environmental Disease     Open Access   (Followers: 2)
European J. of Dentistry     Open Access   (Followers: 2, SJR: 0.496, h-index: 11)
European J. of General Dentistry     Open Access   (Followers: 1)
European J. of Prosthodontics     Open Access   (Followers: 3)
European J. of Psychology and Educational Studies     Open Access   (Followers: 11)
Fertility Science and Research     Open Access  
Formosan J. of Surgery     Open Access   (SJR: 0.107, h-index: 5)
Genome Integrity     Open Access   (Followers: 3, SJR: 1.227, h-index: 12)
Global J. of Transfusion Medicine     Open Access   (Followers: 1)
Heart India     Open Access   (Followers: 1)
Heart Views     Open Access   (Followers: 2)
Hepatitis B Annual     Open Access   (Followers: 3)
IJS Short Reports     Open Access  
Indian Anaesthetists Forum     Open Access  
Indian Dermatology Online J.     Open Access   (Followers: 3)
Indian J. of Allergy, Asthma and Immunology     Open Access   (Followers: 1)
Indian J. of Anaesthesia     Open Access   (Followers: 7, SJR: 0.302, h-index: 13)
Indian J. of Burns     Open Access   (Followers: 1)
Indian J. of Cancer     Open Access   (Followers: 1, SJR: 0.318, h-index: 26)
Indian J. of Cerebral Palsy     Open Access   (Followers: 1)
Indian J. of Community Medicine     Open Access   (Followers: 2, SJR: 0.618, h-index: 16)
Indian J. of Critical Care Medicine     Open Access   (Followers: 2, SJR: 0.307, h-index: 16)
Indian J. of Dental Research     Open Access   (Followers: 4, SJR: 0.243, h-index: 24)
Indian J. of Dental Sciences     Open Access  
Indian J. of Dentistry     Open Access   (Followers: 1)
Indian J. of Dermatology     Open Access   (Followers: 2, SJR: 0.448, h-index: 16)
Indian J. of Dermatology, Venereology and Leprology     Open Access   (Followers: 4, SJR: 0.563, h-index: 29)
Indian J. of Dermatopathology and Diagnostic Dermatology     Open Access  
Indian J. of Drugs in Dermatology     Open Access   (Followers: 1)
Indian J. of Endocrinology and Metabolism     Open Access   (Followers: 4)
Indian J. of Health Sciences     Open Access   (Followers: 2)
Indian J. of Medical and Paediatric Oncology     Open Access   (SJR: 0.292, h-index: 9)
Indian J. of Medical Microbiology     Open Access   (Followers: 1, SJR: 0.53, h-index: 34)
Indian J. of Medical Research     Open Access   (Followers: 4, SJR: 0.716, h-index: 60)
Indian J. of Medical Sciences     Open Access   (Followers: 2, SJR: 0.207, h-index: 31)
Indian J. of Multidisciplinary Dentistry     Open Access   (Followers: 1)
Indian J. of Nephrology     Open Access   (Followers: 2, SJR: 0.233, h-index: 12)
Indian J. of Nuclear Medicine     Open Access   (Followers: 2, SJR: 0.213, h-index: 5)
Indian J. of Occupational and Environmental Medicine     Open Access   (Followers: 3, SJR: 0.203, h-index: 13)
Indian J. of Ophthalmology     Open Access   (Followers: 5, SJR: 0.536, h-index: 34)
Indian J. of Oral Health and Research     Open Access  
Indian J. of Oral Sciences     Open Access   (Followers: 1)
Indian J. of Orthopaedics     Open Access   (Followers: 8, SJR: 0.393, h-index: 15)
Indian J. of Otology     Open Access   (Followers: 1, SJR: 0.218, h-index: 5)
Indian J. of Paediatric Dermatology     Open Access   (Followers: 2)
Indian J. of Pain     Open Access   (Followers: 1)
Indian J. of Palliative Care     Open Access   (Followers: 5, SJR: 0.35, h-index: 12)
Indian J. of Pathology and Microbiology     Open Access   (Followers: 2, SJR: 0.285, h-index: 22)
Indian J. of Pharmacology     Open Access   (SJR: 0.347, h-index: 44)
Indian J. of Plastic Surgery     Open Access   (Followers: 12, SJR: 0.303, h-index: 13)
Indian J. of Psychiatry     Open Access   (Followers: 3, SJR: 0.496, h-index: 15)
Indian J. of Psychological Medicine     Open Access   (SJR: 0.344, h-index: 9)
Indian J. of Public Health     Open Access   (Followers: 1, SJR: 0.444, h-index: 17)
Indian J. of Radiology and Imaging     Open Access   (Followers: 4, SJR: 0.253, h-index: 14)
Indian J. of Research in Homoeopathy     Open Access  
Indian J. of Rheumatology     Open Access   (SJR: 0.169, h-index: 7)
Indian J. of Sexually Transmitted Diseases and AIDS     Open Access   (Followers: 2, SJR: 0.313, h-index: 9)
Indian J. of Social Psychiatry     Open Access   (Followers: 2)
Indian J. of Urology     Open Access   (Followers: 3, SJR: 0.366, h-index: 16)
Indian J. of Vascular and Endovascular Surgery     Open Access   (Followers: 2)
Industrial Psychiatry J.     Open Access   (Followers: 2)
Intl. J. of Academic Medicine     Open Access  
Intl. J. of Advanced Medical and Health Research     Open Access  
Intl. J. of Applied and Basic Medical Research     Open Access  
Intl. J. of Clinical and Experimental Physiology     Open Access   (Followers: 1)
Intl. J. of Critical Illness and Injury Science     Open Access   (Followers: 1)
Intl. J. of Educational and Psychological Researches     Open Access   (Followers: 4)
Intl. J. of Environmental Health Engineering     Open Access   (Followers: 1)
Intl. J. of Forensic Odontology     Open Access   (Followers: 1)
Intl. J. of Green Pharmacy     Open Access   (Followers: 3, SJR: 0.229, h-index: 13)
Intl. J. of Health & Allied Sciences     Open Access   (Followers: 3)
Intl. J. of Health System and Disaster Management     Open Access   (Followers: 3)
Intl. J. of Heart Rhythm     Open Access  
Intl. J. of Medicine and Public Health     Open Access   (Followers: 6)
Intl. J. of Mycobacteriology     Open Access   (SJR: 0.239, h-index: 4)
Intl. J. of Noncommunicable Diseases     Open Access  
Intl. J. of Nutrition, Pharmacology, Neurological Diseases     Open Access   (Followers: 4)
Intl. J. of Oral Health Sciences     Open Access   (Followers: 2)
Intl. J. of Orthodontic Rehabilitation     Open Access  
Intl. J. of Pedodontic Rehabilitation     Open Access  
Intl. J. of Pharmaceutical Investigation     Open Access   (Followers: 1)
Intl. J. of Preventive Medicine     Open Access   (Followers: 1, SJR: 0.523, h-index: 15)
Intl. J. of Shoulder Surgery     Open Access   (Followers: 5, SJR: 0.611, h-index: 9)
Intl. J. of Trichology     Open Access   (SJR: 0.37, h-index: 10)
Intl. J. of Yoga     Open Access   (Followers: 13)
Intl. J. of Yoga : Philosophy, Psychology and Parapsychology     Open Access   (Followers: 5)
Iranian J. of Nursing and Midwifery Research     Open Access   (Followers: 3)
Iraqi J. of Hematology     Open Access  
J. of Academy of Medical Sciences     Open Access  
J. of Advanced Pharmaceutical Technology & Research     Open Access   (Followers: 3, SJR: 0.427, h-index: 15)
J. of Anaesthesiology Clinical Pharmacology     Open Access   (Followers: 7, SJR: 0.416, h-index: 14)
J. of Applied Hematology     Open Access   (Followers: 1)
J. of Association of Chest Physicians     Open Access   (Followers: 2)
J. of Basic and Clinical Reproductive Sciences     Open Access   (Followers: 1)
J. of Cancer Research and Therapeutics     Open Access   (Followers: 5, SJR: 0.359, h-index: 21)
J. of Carcinogenesis     Open Access   (Followers: 1, SJR: 1.152, h-index: 26)
J. of Cardiothoracic Trauma     Open Access  
J. of Cardiovascular Disease Research     Open Access   (Followers: 3, SJR: 0.351, h-index: 13)
J. of Cardiovascular Echography     Open Access   (Followers: 1, SJR: 0.134, h-index: 2)
J. of Cleft Lip Palate and Craniofacial Anomalies     Open Access   (Followers: 2)
J. of Clinical and Preventive Cardiology     Open Access   (Followers: 1)
J. of Clinical Imaging Science     Open Access   (Followers: 1, SJR: 0.277, h-index: 8)
J. of Clinical Neonatology     Open Access   (Followers: 2)
J. of Clinical Ophthalmology and Research     Open Access   (Followers: 3)
J. of Clinical Sciences     Open Access  
J. of Conservative Dentistry     Open Access   (Followers: 4, SJR: 0.532, h-index: 10)
J. of Craniovertebral Junction and Spine     Open Access   (Followers: 4, SJR: 0.199, h-index: 9)
J. of Current Medical Research and Practice     Open Access  
J. of Current Research in Scientific Medicine     Open Access  
J. of Cutaneous and Aesthetic Surgery     Open Access   (Followers: 1)
J. of Cytology     Open Access   (Followers: 1, SJR: 0.274, h-index: 9)
J. of Dental and Allied Sciences     Open Access   (Followers: 2)
J. of Dental Implants     Open Access   (Followers: 7)
J. of Dental Lasers     Open Access   (Followers: 2)
J. of Dental Research and Review     Open Access   (Followers: 1)
J. of Digestive Endoscopy     Open Access   (Followers: 2)
J. of Dr. NTR University of Health Sciences     Open Access  
J. of Earth, Environment and Health Sciences     Open Access   (Followers: 1)
J. of Education and Ethics in Dentistry     Open Access   (Followers: 5)
J. of Education and Health Promotion     Open Access   (Followers: 5)
J. of Emergencies, Trauma and Shock     Open Access   (Followers: 9, SJR: 0.353, h-index: 14)
J. of Engineering and Technology     Open Access   (Followers: 6)
J. of Experimental and Clinical Anatomy     Open Access   (Followers: 2)
J. of Family and Community Medicine     Open Access   (Followers: 2)
J. of Family Medicine and Primary Care     Open Access   (Followers: 11)

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Journal Cover Digital Medicine
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  This is an Open Access Journal Open Access journal
   ISSN (Print) 2542-629X - ISSN (Online) 2226-8561
   Published by Medknow Publishers Homepage  [355 journals]
  • Taiyuan global health conference 2017

    • Authors: David John Wortley
      Pages: 147 - 149
      Abstract: David John Wortley
      Digital Medicine 2017 3(4):147-149

      Citation: Digital Medicine 2017 3(4):147-149
      PubDate: Mon,26 Mar 2018
      DOI: 10.4103/digm.digm_47_17
      Issue No: Vol. 3, No. 4 (2018)
       
  • The increasing role of use of computer-based methods in disease diagnosis

    • Authors: Thanapong Chaichana, Zhonghua Sun, Anthony Lucey, David Reid, Atulya Nagar
      Pages: 150 - 153
      Abstract: Thanapong Chaichana, Zhonghua Sun, Anthony Lucey, David Reid, Atulya Nagar
      Digital Medicine 2017 3(4):150-153

      Citation: Digital Medicine 2017 3(4):150-153
      PubDate: Mon,26 Mar 2018
      DOI: 10.4103/digm.digm_40_17
      Issue No: Vol. 3, No. 4 (2018)
       
  • Evolution of the digital biomarker ecosystem

    • Authors: Justin M Wright, Oliver B Regele, Lampros C Kourtis, Sean M Pszenny, Rhea Sirkar, Christopher Kovalchick, Graham Barry Jones
      Pages: 154 - 163
      Abstract: Justin M Wright, Oliver B Regele, Lampros C Kourtis, Sean M Pszenny, Rhea Sirkar, Christopher Kovalchick, Graham Barry Jones
      Digital Medicine 2017 3(4):154-163
      The pursuit of digital biomarkers wherein signal outputs from biosensors are collated to inform health-care decisions continues to evolve at a rapid pace. In the field of neurodegenerative disorders, a goal is to augment subjective patient-reported inputs with patient-independent verifiable data that can be used to recommend interventive measures. For example, in the case of Alzheimer's disease, such tools might preselect patients in the presymptomatic and prodromal phases for definitive positron emission tomographic analysis, allowing accurate staging of disease and providing a reference point for subsequent therapeutic and other measures. Selection of appropriate and meaningful digital biomarkers to pursue, however, requires deep understanding of the disease state and its ecological relationship to the instrumental activities of daily living scale. Similar opportunities and challenges exist in a number of other chronic disease states including Parkinson's, Huntington's, and Duchenne's disease, multiple sclerosis, and cardiovascular disease. This review will highlight progress in device technology, the need for holistic approaches for data inputs, and regulatory pathways for adoption. The review focuses on published work from the period 2012–2017 derived from online searches of the most widely used abstracting portals.
      Citation: Digital Medicine 2017 3(4):154-163
      PubDate: Mon,26 Mar 2018
      DOI: 10.4103/digm.digm_35_17
      Issue No: Vol. 3, No. 4 (2018)
       
  • Three-dimensional visualization technology in the diagnosis and treatment
           of malignant tumor in the hilar bile duct to the upper segment of common
           bile duct

    • Authors: Yanping He, Weidong Di, Yanzhong Zhang, Jianghuai Li
      Pages: 164 - 169
      Abstract: Yanping He, Weidong Di, Yanzhong Zhang, Jianghuai Li
      Digital Medicine 2017 3(4):164-169
      Background and Objectives: The aim of this study is to investigate the application of three-dimensional (3D) visualization technique in the surgical treatment of malignant tumors of the hilar and common bile ducts. Materials and Methods: A total of 23 patients admitted from January 2015 to April 2017 for surgical treatment were analyzed, of whom 13 patients underwent medical image 3D visualization system (treatment group) while 10 underwent surgery alone (control group). Indicators to the treatment effects were recorded and compared between the two groups, including the operation time, intraoperative bleeding volume, postoperative hospitalization time, the number of dissected lymph nodes, the incidence of all postoperative complications, and the alanine transaminase (ALT), albumin (ALB), and total bilirubin (TBIL) monitored on days 1, 3, 5, and 7 after the operation. Results: In the treatment group and control group, the operation time was 194.66 ± 13.79 and 230.81 ± 27.07 min (t = 3.857, P = 0.002), the intraoperative bleeding volume was 274.28 ± 44.57 and 320.69 ± 35.90 mL (t = 2.686, P = 0.014), the postoperative hospitalization time was 11.15 ± 1.25 and 15.25 ± 1.75d (t = 6.557, P = 0.000), the number of dissected lymph nodes 10.46 ± 1.71 and 7.40 ± 0.97 (t = 5.050, P = 0.000), and the incidence of all postoperative complications 7.69% and 60% (χ2 = 7.304, P = 0.019), respectively. The level of ALT and TBIL was significantly higher in the treatment group than in the control group, whereas the level of ALB was significantly lower in the treatment group than in the control group on days 3, 5, and 7 (P < 0.05). The recovery of liver function was better in the treatment group than in the control group. In addition, no perioperative deaths were found in either group. Conclusions: In the surgical treatment of malignant tumors occurring in the hilar to the common bile duct, 3D visualization technology can reduce the operation injury and intraoperative bleeding, decrease the incidence of postoperative complications, improve the safety and effectiveness of the operation, and promote the recovery of liver function, thus demonstrating promising short-term efficacy.
      Citation: Digital Medicine 2017 3(4):164-169
      PubDate: Mon,26 Mar 2018
      DOI: 10.4103/digm.digm_43_17
      Issue No: Vol. 3, No. 4 (2018)
       
  • Patient-specific three-dimensional printed pulmonary artery model: A
           preliminary study

    • Authors: Sultan Aldosari, Andrew Squelch, Zhonghua Sun
      Pages: 170 - 177
      Abstract: Sultan Aldosari, Andrew Squelch, Zhonghua Sun
      Digital Medicine 2017 3(4):170-177
      Background and Objectives: Three-dimensional (3D) printing has potential value in medical applications with increasing reports in the diagnostic assessment of cardiovascular diseases. The use of 3D printing in replicating pulmonary artery anatomy and diagnosing pulmonary embolism is very limited. The purpose of this study was to develop a 3D printed pulmonary artery model and test different computed tomography (CT) scanning protocols for determination of an optimal protocol with acceptable image quality but low radiation dose. Materials and Methods: A patient-specific 3D printed pulmonary artery model was created based on contrast-enhanced CT images in a patient with suspected pulmonary embolism. Different CT pulmonary angiography protocols consisting of 80, 100, and 120 kVp, pitch 0.7, 0.9, and 1.2 with 1 mm slice thickness, and 0.6 mm reconstruction interval were tested on the phantom. Quantitative assessment of image quality in terms of signal-to-noise ratio (SNR) was measured in the images acquired with different protocols. Measurements in pulmonary artery diameters were conducted and compared between pre- and post-3D printed images and 3D printed model. Results: The 3D printed model was found to replicate normal pulmonary artery with high accuracy. The mean difference in diameter measurements was <0.8 mm (<0.5% deviation in diameter). There was no significant difference in SNR measured between these CT protocols (P = 0.96–0.99). Radiation dose was reduced by 55% and 75% when lowering kVp from 120 to 100 and 80 kVp, without affecting image quality. Conclusions: It is feasible to produce a 3D printed pulmonary artery model with high accuracy in replicating normal anatomy. Different CT scanning protocols are successfully tested on the model with 80 kVp and pitch 0.9 being the optimal one with resultant diagnostic images but at much lower radiation dose.
      Citation: Digital Medicine 2017 3(4):170-177
      PubDate: Mon,26 Mar 2018
      DOI: 10.4103/digm.digm_42_17
      Issue No: Vol. 3, No. 4 (2018)
       
  • Nonrigid registration of multimodal medical images based on hybrid model

    • Authors: Nuo Tong, Shuiping Gou, Teng Xu, Ke Sheng, Shuyuan Yang
      Pages: 178 - 185
      Abstract: Nuo Tong, Shuiping Gou, Teng Xu, Ke Sheng, Shuyuan Yang
      Digital Medicine 2017 3(4):178-185
      Background and Objectives: Multimodal image registration is a crucial step in prostate cancer radiation therapy scheme. However, it can be challenging due to the obvious appearance difference between computed tomography (CT) and magnetic resonance imaging (MRI) and unavoidable organ motion. Accordingly, a nonrigid registration framework for precisely registering multimodal prostate images is proposed in this paper. Materials and Methods: In this work, multimodal prostate image registration between CT and MRI is achieved using a hybrid model that integrates multiresolution strategy and Demons algorithm. Furthermore, to precisely describe the deformation of prostate, B-spline-based registration is utilized to refine the initial registration result of multiresolution Demons algorithm. Results: To evaluate our method, experiments on clinical prostate data sets of nine participants and comparison with the conventional Demons algorithm are conducted. Experimental results demonstrate that the proposed registration method outperforms the Demons algorithm by a large margin in terms of mutual information and correlation coefficient. Conclusions: These results show that our method outperforms the Demons algorithm and can achieve excellent performance on multimodal prostate images even the appearances of prostate change significantly. In addition, the results demonstrate that the proposed method can help to localize the prostate accurately, which is feasible in clinical.
      Citation: Digital Medicine 2017 3(4):178-185
      PubDate: Mon,26 Mar 2018
      DOI: 10.4103/digm.digm_39_17
      Issue No: Vol. 3, No. 4 (2018)
       
  • Evaluation of different atlas selection strategies for multi-atlas
           segmentation of low-dose computed tomographic images of whole-body
           positron emission tomography/computed tomography

    • Authors: Hongkai Wang, Nan Zhang, Li Huo, Bin Zhang
      Pages: 186 - 192
      Abstract: Hongkai Wang, Nan Zhang, Li Huo, Bin Zhang
      Digital Medicine 2017 3(4):186-192
      Background and Objectives: The increasing clinical use of torso positron emission tomography/computed tomography (PET/CT) demands automated segmentation of torso organs from PET/CT images. We attempt to use the multi-atlas segmentation approach for trunk organ segmentation from the low-dose CT images of PET/CT. Since atlas selection is a prerequisite step for multi-atlas segmentation, this study focuses on evaluating the performance of different atlas selection strategies for torso organ segmentation. Methods: We evaluated two criteria for atlas selection, including image similarity and body mass index (BMI) difference between the atlas and the target image. Based on the two criteria, ten atlases are selected and registered to the target image, followed by the label fusion step to achieve final segmentation. Results: The BMI criterion yields comparable segmentation accuracy to the image similarity criterion but with much less computation time. All the evaluated atlas selection methods have Dice >0.9 for the lungs, heart, and liver and Dice < 0.85 for the skeleton, spleen, and kidneys. The inter-method differences are not significant for the high-contrast and big-sized organs such as skeleton, lungs, heart, and liver. For the low-contrast and smaller-sized organs such as spleen and kidneys, none of the atlas selection methods significantly outperforms random atlas selection. Conclusions: BMI is an effective and efficient atlas selection criterion for low-dose torso CT images. The spleen and kidneys are difficult to get good segmentation, no matter which atlas selection method is used. It is important to develop more effective atlas selection methods for the spleen and kidneys.
      Citation: Digital Medicine 2017 3(4):186-192
      PubDate: Mon,26 Mar 2018
      DOI: 10.4103/digm.digm_36_17
      Issue No: Vol. 3, No. 4 (2018)
       
 
 
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