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Showing 1 - 200 of 355 Journals sorted alphabetically
Advanced Arab Academy of Audio-Vestibulogy J.     Open Access  
Advances in Human Biology     Open Access   (Followers: 1)
African J. for Infertility and Assisted Conception     Open Access  
African J. of Business Ethics     Open Access   (Followers: 6)
African J. of Medical and Health Sciences     Open Access   (Followers: 2)
African J. of Paediatric Surgery     Open Access   (Followers: 7, SJR: 0.269, h-index: 10)
African J. of Trauma     Open Access  
Ain-Shams J. of Anaesthesiology     Open Access   (Followers: 3)
Al-Azhar Assiut Medical J.     Open Access  
Al-Basar Intl. J. of Ophthalmology     Open Access   (Followers: 1)
Ancient Science of Life     Open Access   (Followers: 6)
Anesthesia : Essays and Researches     Open Access   (Followers: 8)
Annals of African Medicine     Open Access   (Followers: 1, SJR: 0.331, h-index: 15)
Annals of Bioanthropology     Open Access   (Followers: 3)
Annals of Cardiac Anaesthesia     Open Access   (Followers: 14, SJR: 0.408, h-index: 15)
Annals of Indian Academy of Neurology     Open Access   (Followers: 3, SJR: 0.308, h-index: 14)
Annals of Maxillofacial Surgery     Open Access   (Followers: 6)
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 7, SJR: 0.441, h-index: 10)
Annals of Saudi Medicine     Open Access   (SJR: 0.24, h-index: 29)
Annals of Thoracic Medicine     Open Access   (Followers: 4, SJR: 0.388, h-index: 19)
Annals of Tropical Medicine and Public Health     Open Access   (Followers: 15, SJR: 0.148, h-index: 5)
APOS Trends in Orthodontics     Open Access   (Followers: 1)
Arab J. of Interventional Radiology     Open Access  
Archives of Intl. Surgery     Open Access   (Followers: 9)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Archives of Pharmacy Practice     Open Access   (Followers: 6)
Asia Pacific J. of Clinical Trials : Nervous System Diseases     Open Access  
Asia-Pacific J. of Oncology Nursing     Open Access   (Followers: 3)
Asian J. of Andrology     Open Access   (Followers: 1, SJR: 0.879, h-index: 49)
Asian J. of Neurosurgery     Open Access   (Followers: 2)
Asian J. of Oncology     Open Access   (Followers: 1)
Asian J. of Transfusion Science     Open Access   (Followers: 2, SJR: 0.362, h-index: 10)
Astrocyte     Open Access  
Avicenna J. of Medicine     Open Access   (Followers: 1)
AYU : An international quarterly journal of research in Ayurveda     Open Access   (Followers: 6)
Benha Medical J.     Open Access  
BLDE University J. of Health Sciences     Open Access  
Brain Circulation     Open Access  
Bulletin of Faculty of Physical Therapy     Open Access   (Followers: 1)
Cancer Translational Medicine     Open Access   (Followers: 1)
CHRISMED J. of Health and Research     Open Access  
Clinical Dermatology Review     Open Access   (Followers: 1)
Clinical Trials in Degenerative Diseases     Open Access  
Clinical Trials in Orthopedic Disorders     Open Access   (Followers: 1)
Community Acquired Infection     Open Access  
Conservation and Society     Open Access   (Followers: 12, SJR: 0.82, h-index: 12)
Contemporary Clinical Dentistry     Open Access   (Followers: 4)
Current Medical Issues     Open Access   (Followers: 1)
CytoJ.     Open Access   (Followers: 2, SJR: 0.339, h-index: 19)
Delta J. of Ophthalmology     Open Access  
Dental Hypotheses     Open Access   (Followers: 3, SJR: 0.131, h-index: 4)
Dental Research J.     Open Access   (Followers: 9)
Dentistry and Medical Research     Open Access  
Digital Medicine     Open Access  
Drug Development and Therapeutics     Open Access  
Education for Health     Open Access   (Followers: 5, SJR: 0.205, h-index: 22)
Egyptian J. of Bronchology     Open Access  
Egyptian J. of Cardiothoracic Anesthesia     Open Access  
Egyptian J. of Cataract and Refractive Surgery     Open Access   (Followers: 1)
Egyptian J. of Dermatology and Venerology     Open Access   (Followers: 1)
Egyptian J. of Haematology     Open Access  
Egyptian J. of Internal Medicine     Open Access   (Followers: 1)
Egyptian J. of Neurology, Psychiatry and Neurosurgery     Open Access   (Followers: 1, SJR: 0.121, h-index: 3)
Egyptian J. of Obesity, Diabetes and Endocrinology     Open Access  
Egyptian J. of Otolaryngology     Open Access   (Followers: 2)
Egyptian J. of Psychiatry     Open Access   (Followers: 2)
Egyptian J. of Surgery     Open Access   (Followers: 1)
Egyptian Orthopaedic J.     Open Access  
Egyptian Pharmaceutical J.     Open Access  
Egyptian Retina J.     Open Access  
Egyptian Rheumatology and Rehabilitation     Open Access  
Endodontology     Open Access  
Endoscopic Ultrasound     Open Access   (SJR: 0.473, h-index: 8)
Environmental Disease     Open Access   (Followers: 2)
European J. of Dentistry     Open Access   (Followers: 2, SJR: 0.496, h-index: 11)
European J. of General Dentistry     Open Access   (Followers: 1)
European J. of Prosthodontics     Open Access   (Followers: 2)
European J. of Psychology and Educational Studies     Open Access   (Followers: 8)
Fertility Science and Research     Open Access  
Formosan J. of Surgery     Open Access   (SJR: 0.107, h-index: 5)
Genome Integrity     Open Access   (Followers: 4, SJR: 1.227, h-index: 12)
Global J. of Transfusion Medicine     Open Access   (Followers: 1)
Heart India     Open Access   (Followers: 1)
Heart Views     Open Access   (Followers: 2)
Hepatitis B Annual     Open Access   (Followers: 3)
IJS Short Reports     Open Access  
Indian Anaesthetists Forum     Open Access  
Indian Dermatology Online J.     Open Access   (Followers: 3)
Indian J. of Allergy, Asthma and Immunology     Open Access   (Followers: 1)
Indian J. of Anaesthesia     Open Access   (Followers: 8, SJR: 0.302, h-index: 13)
Indian J. of Burns     Open Access   (Followers: 1)
Indian J. of Cancer     Open Access   (SJR: 0.318, h-index: 26)
Indian J. of Cerebral Palsy     Open Access   (Followers: 1)
Indian J. of Community Medicine     Open Access   (Followers: 2, SJR: 0.618, h-index: 16)
Indian J. of Critical Care Medicine     Open Access   (Followers: 2, SJR: 0.307, h-index: 16)
Indian J. of Dental Research     Open Access   (Followers: 4, SJR: 0.243, h-index: 24)
Indian J. of Dental Sciences     Open Access  
Indian J. of Dentistry     Open Access   (Followers: 1)
Indian J. of Dermatology     Open Access   (Followers: 2, SJR: 0.448, h-index: 16)
Indian J. of Dermatology, Venereology and Leprology     Open Access   (Followers: 3, SJR: 0.563, h-index: 29)
Indian J. of Dermatopathology and Diagnostic Dermatology     Open Access  
Indian J. of Drugs in Dermatology     Open Access   (Followers: 1)
Indian J. of Endocrinology and Metabolism     Open Access   (Followers: 4)
Indian J. of Health Sciences     Open Access   (Followers: 2)
Indian J. of Medical and Paediatric Oncology     Open Access   (SJR: 0.292, h-index: 9)
Indian J. of Medical Microbiology     Open Access   (Followers: 1, SJR: 0.53, h-index: 34)
Indian J. of Medical Research     Open Access   (Followers: 4, SJR: 0.716, h-index: 60)
Indian J. of Medical Sciences     Open Access   (Followers: 2, SJR: 0.207, h-index: 31)
Indian J. of Multidisciplinary Dentistry     Open Access   (Followers: 1)
Indian J. of Nephrology     Open Access   (Followers: 2, SJR: 0.233, h-index: 12)
Indian J. of Nuclear Medicine     Open Access   (Followers: 2, SJR: 0.213, h-index: 5)
Indian J. of Occupational and Environmental Medicine     Open Access   (Followers: 4, SJR: 0.203, h-index: 13)
Indian J. of Ophthalmology     Open Access   (Followers: 5, SJR: 0.536, h-index: 34)
Indian J. of Oral Health and Research     Open Access  
Indian J. of Oral Sciences     Open Access   (Followers: 1)
Indian J. of Orthopaedics     Open Access   (Followers: 9, SJR: 0.393, h-index: 15)
Indian J. of Otology     Open Access   (Followers: 1, SJR: 0.218, h-index: 5)
Indian J. of Paediatric Dermatology     Open Access   (Followers: 2)
Indian J. of Pain     Open Access   (Followers: 1)
Indian J. of Palliative Care     Open Access   (Followers: 5, SJR: 0.35, h-index: 12)
Indian J. of Pathology and Microbiology     Open Access   (Followers: 1, SJR: 0.285, h-index: 22)
Indian J. of Pharmacology     Open Access   (SJR: 0.347, h-index: 44)
Indian J. of Plastic Surgery     Open Access   (Followers: 12, SJR: 0.303, h-index: 13)
Indian J. of Psychiatry     Open Access   (Followers: 3, SJR: 0.496, h-index: 15)
Indian J. of Psychological Medicine     Open Access   (Followers: 1, SJR: 0.344, h-index: 9)
Indian J. of Public Health     Open Access   (Followers: 1, SJR: 0.444, h-index: 17)
Indian J. of Radiology and Imaging     Open Access   (Followers: 4, SJR: 0.253, h-index: 14)
Indian J. of Research in Homoeopathy     Open Access  
Indian J. of Rheumatology     Open Access   (SJR: 0.169, h-index: 7)
Indian J. of Sexually Transmitted Diseases and AIDS     Open Access   (Followers: 2, SJR: 0.313, h-index: 9)
Indian J. of Social Psychiatry     Open Access   (Followers: 2)
Indian J. of Urology     Open Access   (Followers: 3, SJR: 0.366, h-index: 16)
Indian J. of Vascular and Endovascular Surgery     Open Access   (Followers: 2)
Industrial Psychiatry J.     Open Access   (Followers: 2)
Intl. J. of Academic Medicine     Open Access  
Intl. J. of Advanced Medical and Health Research     Open Access  
Intl. J. of Applied and Basic Medical Research     Open Access  
Intl. J. of Clinical and Experimental Physiology     Open Access   (Followers: 1)
Intl. J. of Critical Illness and Injury Science     Open Access   (Followers: 1)
Intl. J. of Educational and Psychological Researches     Open Access   (Followers: 4)
Intl. J. of Environmental Health Engineering     Open Access   (Followers: 1)
Intl. J. of Forensic Odontology     Open Access   (Followers: 1)
Intl. J. of Green Pharmacy     Open Access   (Followers: 4, SJR: 0.229, h-index: 13)
Intl. J. of Health & Allied Sciences     Open Access   (Followers: 3)
Intl. J. of Health System and Disaster Management     Open Access   (Followers: 3)
Intl. J. of Heart Rhythm     Open Access  
Intl. J. of Medicine and Public Health     Open Access   (Followers: 7)
Intl. J. of Mycobacteriology     Open Access   (SJR: 0.239, h-index: 4)
Intl. J. of Noncommunicable Diseases     Open Access  
Intl. J. of Nutrition, Pharmacology, Neurological Diseases     Open Access   (Followers: 4)
Intl. J. of Oral Health Sciences     Open Access   (Followers: 1)
Intl. J. of Orthodontic Rehabilitation     Open Access  
Intl. J. of Pedodontic Rehabilitation     Open Access  
Intl. J. of Pharmaceutical Investigation     Open Access   (Followers: 1)
Intl. J. of Preventive Medicine     Open Access   (Followers: 1, SJR: 0.523, h-index: 15)
Intl. J. of Shoulder Surgery     Open Access   (Followers: 7, SJR: 0.611, h-index: 9)
Intl. J. of Trichology     Open Access   (SJR: 0.37, h-index: 10)
Intl. J. of Yoga     Open Access   (Followers: 15)
Intl. J. of Yoga : Philosophy, Psychology and Parapsychology     Open Access   (Followers: 6)
Iranian J. of Nursing and Midwifery Research     Open Access   (Followers: 3)
Iraqi J. of Hematology     Open Access  
J. of Academy of Medical Sciences     Open Access  
J. of Advanced Pharmaceutical Technology & Research     Open Access   (Followers: 4, SJR: 0.427, h-index: 15)
J. of Anaesthesiology Clinical Pharmacology     Open Access   (Followers: 8, SJR: 0.416, h-index: 14)
J. of Applied Hematology     Open Access  
J. of Association of Chest Physicians     Open Access   (Followers: 2)
J. of Basic and Clinical Reproductive Sciences     Open Access   (Followers: 1)
J. of Cancer Research and Therapeutics     Open Access   (Followers: 4, SJR: 0.359, h-index: 21)
J. of Carcinogenesis     Open Access   (Followers: 1, SJR: 1.152, h-index: 26)
J. of Cardiothoracic Trauma     Open Access  
J. of Cardiovascular Disease Research     Open Access   (Followers: 3, SJR: 0.351, h-index: 13)
J. of Cardiovascular Echography     Open Access   (SJR: 0.134, h-index: 2)
J. of Cleft Lip Palate and Craniofacial Anomalies     Open Access   (Followers: 2)
J. of Clinical and Preventive Cardiology     Open Access   (Followers: 1)
J. of Clinical Imaging Science     Open Access   (Followers: 1, SJR: 0.277, h-index: 8)
J. of Clinical Neonatology     Open Access   (Followers: 1)
J. of Clinical Ophthalmology and Research     Open Access   (Followers: 2)
J. of Clinical Sciences     Open Access  
J. of Conservative Dentistry     Open Access   (Followers: 4, SJR: 0.532, h-index: 10)
J. of Craniovertebral Junction and Spine     Open Access   (Followers: 4, SJR: 0.199, h-index: 9)
J. of Current Medical Research and Practice     Open Access  
J. of Current Research in Scientific Medicine     Open Access  
J. of Cutaneous and Aesthetic Surgery     Open Access   (Followers: 1)
J. of Cytology     Open Access   (Followers: 1, SJR: 0.274, h-index: 9)
J. of Dental and Allied Sciences     Open Access   (Followers: 1)
J. of Dental Implants     Open Access   (Followers: 7)
J. of Dental Lasers     Open Access   (Followers: 2)
J. of Dental Research and Review     Open Access   (Followers: 1)
J. of Digestive Endoscopy     Open Access   (Followers: 3)
J. of Dr. NTR University of Health Sciences     Open Access  
J. of Earth, Environment and Health Sciences     Open Access   (Followers: 1)
J. of Education and Ethics in Dentistry     Open Access   (Followers: 5)
J. of Education and Health Promotion     Open Access   (Followers: 5)
J. of Emergencies, Trauma and Shock     Open Access   (Followers: 9, SJR: 0.353, h-index: 14)
J. of Engineering and Technology     Open Access   (Followers: 6)
J. of Experimental and Clinical Anatomy     Open Access   (Followers: 2)
J. of Family and Community Medicine     Open Access   (Followers: 2)
J. of Family Medicine and Primary Care     Open Access   (Followers: 11)

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Journal Cover Egyptian Journal of Internal Medicine
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  This is an Open Access Journal Open Access journal
   ISSN (Print) 1110-7782 - ISSN (Online) 2090-9098
   Published by Medknow Publishers Homepage  [355 journals]
  • Type 1 diabetes mellitus and enterovirus linkage: search for associated
           etiopathology

    • Authors: Idris Abdullahi Nasir, Anthony U Emeribe, Halima A Shuwa, Maryam M Zakari, Nkechi Onukegbe Peters
      Pages: 93 - 99
      Abstract: Idris Abdullahi Nasir, Anthony U Emeribe, Halima A Shuwa, Maryam M Zakari, Nkechi Onukegbe Peters
      The Egyptian Journal of Internal Medicine 2017 29(3):93-99
      Type 1 diabetes (T1D) is believed to have complex interplay between several enteroviruses (EVs) and host immune system disturbance induced or accelerated by viral pathogenesis. In the past two decades, there has been global upsurge in the incidence of childhood T1D, especially in those less than 5 years. Because of the ubiquity and persistence of EVs in human bowel and their tropism to pancreatic cells, they tend to express certain viral proteins that have propensity for genetic manipulation and activation of autoimmunity that could be potentially linked to T1D. In view of these, we present this review of existing literature in order to analyze the epidemiology and possible association between EV infections, host immune dysfunction, and development of autoimmunity or T1D with the view to encourage the investigation of EV infections and associated virus-induced islet cells autoimmunity and immunopathy in genetically predisposed children.
      Citation: The Egyptian Journal of Internal Medicine 2017 29(3):93-99
      PubDate: Fri,15 Sep 2017
      DOI: 10.4103/ejim.ejim_25_17
      Issue No: Vol. 29, No. 3 (2017)
       
  • Relation of serum magnesium level to microvascular complications and the
           components of metabolic syndrome in patients with type 2 diabetes mellitus
           

    • Authors: Heba M Yossef, Nashwa S Ghanem, Ula M Al-Jarhi, Ollfat G Shaker
      Pages: 100 - 104
      Abstract: Heba M Yossef, Nashwa S Ghanem, Ula M Al-Jarhi, Ollfat G Shaker
      The Egyptian Journal of Internal Medicine 2017 29(3):100-104
      Background and aimDiabetes mellitus is associated with magnesium (Mg) depletion in intracellular and extracellular compartments. Hypomagnesemia has been suggested to be associated with macrovascular and microvascular complications of diabetes. The effect of the metabolic syndrome (MetS) has markedly increased. Recently, there is increasing evidence that dietary Mg intake and supplementation are inversely associated with the risk for MetS and its components.The aim of this study is to evaluate the relation of Mg level to diabetes, its microvascular complications, and MetS components in Egyptian patients with type 2 diabetes mellitus.Patients and methodsThe study involved 90 patients older than 35 years who were divided into two groups: 70 patients with type 2 diabetes and 20 patients as control. Patients’ group was subdivided into those with complications (neuropathy, retinopathy, and nephropathy) and those without complications. For every patient, history and clinical examination including blood pressure, waist circumference, testing for peripheral neuropathy, and fundus examination were done. Fasting blood sugar (FBS) and 2-h postprandial blood sugar (2-h PPBS), glycated hemoglobin (HbA1c), albumin/creatinine ratio, creatinine level, total cholesterol, high-density lipoprotein-cholesterol, triglycerides, and serum Mg were obtained.ResultsSerum Mg was significantly lower in diabetic patients than in control (P=0.007). Hypomagnesemia was detected in 56 (80%) patients and none of control. Mg was lower in patients with complications than in patients without; however, the difference was statistically insignificant. Statistically significant negative correlation between serum Mg with serum cholesterol, triglyceride, creatinine level, albumin/creatinine ratio, FBS, 2-h PPBS, and HbA1c was found.ConclusionHypomagnesemia is prevalent in diabetic patients. It is associated with diabetic complications and poor glycemic control. High plasma triglycerides, total cholesterol, creatinine level, albuminuria, HbA1c, FBS, and 2-h PPBS are independent correlates of hypomagnesemia.
      Citation: The Egyptian Journal of Internal Medicine 2017 29(3):100-104
      PubDate: Fri,15 Sep 2017
      DOI: 10.4103/ejim.ejim_22_17
      Issue No: Vol. 29, No. 3 (2017)
       
  • Creatinine, cystatin, and combined-based equations in assessment of renal
           functions in type 2 diabetic Egyptian patients

    • Authors: Mahmoud M Elnokeety, Amr M Shaker, Ahmed M Fayed
      Pages: 105 - 111
      Abstract: Mahmoud M Elnokeety, Amr M Shaker, Ahmed M Fayed
      The Egyptian Journal of Internal Medicine 2017 29(3):105-111
      BackgroundDiabetic nephropathy is the principal single cause of end-stage renal disease. The most important parameter in the clinical evaluation of kidney function is the glomerular filtration rate (GFR), which is generally accepted as the best overall index of kidney function; GFR remains the cornerstone of the clinical evaluation of overall kidney function. Our study was performed to compare between estimated GFR equations based on serum creatinine and/or cystatin C performance in relation to measured GFR using radionuclide study and degree of proteinuria.Patients and methodsIn our cross-sectional study, 80 adult type 2 diabetic patients, with diabetic nephropathy and proteinuria more than 300 mg/24 h, were included after application of inclusion and exclusion criteria, and subjected to history taking, clinical examination, and laboratory investigation including serum creatinine, cystatin C, 24-h urinary protein/creatinine clearance, and renal isotope technetium-99m-diethylene triamine pentaacetic acid scanning.ResultsThere was a linear correlation between serum creatinine and cystatin C (r=0.867, P=0.000). Cystatin C was better correlated (r=−0.781, P=0.000) with isotopically measured GFR than creatinine (r=−0.106, P=0.348). Cystatin C was better than creatinine in all estimated GFR equations tested in our study [Modification of Diet in Renal Disease, Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) Cr 2009, CKD-EPI Cr-Cys 2012, CKD-EPI Cys 2012]. The best performance among all equations tested when compared with isotopically measured GFR was the CKD-EPI Cr-Cyst 2012 (r=0.816, P=0.000). Cystatin C showed a significant negative correlation with hemoglobin level, a finding that could not be established with serum creatinine; there was no significant association of creatinine or cystatin with the level of proteinuria.ConclusionIn patients with early overt diabetic nephropathy, serum cystatin C showed a significantly stronger correlation than creatinine with isotopically measured GFR, and among the studied equations for GFR estimation the CKD-EPI Cr-Cyst 2012 equation performed best.
      Citation: The Egyptian Journal of Internal Medicine 2017 29(3):105-111
      PubDate: Fri,15 Sep 2017
      DOI: 10.4103/ejim.ejim_26_17
      Issue No: Vol. 29, No. 3 (2017)
       
  • The relationship between anemia, serum hepcidin levels, and chronic
           hepatitis C in chronic hemodialysis patients

    • Authors: Maher A Al-Amir, Ahmed A Hassan, Shahira M Elshafie, Heba M Zein Elabdin, Sara A Taha
      Pages: 112 - 116
      Abstract: Maher A Al-Amir, Ahmed A Hassan, Shahira M Elshafie, Heba M Zein Elabdin, Sara A Taha
      The Egyptian Journal of Internal Medicine 2017 29(3):112-116
      BackgroundHepcidin is a small peptide that is produced by hepatocytes and circulates in the plasma. It plays a central role in regulating the iron status in the body.AimThe aim of this study was to measure serum hepcidin levels in maintenance hemodialysis (MHD) patients and identify a possible impact of chronic hepatitis C virus (HCV) infection on the severity of anemia.Patients and methodsThis cross-sectional study was conducted on a cohort of 80 MHD patients (40 HCV positive and 40 HCV negative) and 20 healthy age-matched and sex-matched participants who participated as normal controls. Serum hepcidin and highly-sensitive C-reactive protein were measured in patients to study their possible effect on hematological and inflammatory parameters when compared with the control group.ResultsMHD patients had significantly higher serum hepcidin levels than did controls. The HCV-positive group had significantly lower serum hepcidin and ferritin levels when compared with the HCV-negative group. All MHD patients had significantly higher levels of serum highly-sensitive C-reactive protein than did controls. Hepcidin was also found to correlate with age and serum ferritin levels among MHD patients.ConclusionChanges in serum hepcidin levels are associated with iron status and microinflammation in MHD patients. If used as a diagnostic tool, it may improve targeting and timing of iron therapy by identifying patients during periods of reticuloendothelial blockage of iron transport. This is important to avoid iron overload, especially in HCV-positive patients, which may otherwise cause liver injury resulting in fibrosis, cirrhosis, and finally HCC. We also revealed the value of ferritin levels, which seemed to play an important role in determining the severity of liver disease related to liver fibrosis and microinflammatory activity.
      Citation: The Egyptian Journal of Internal Medicine 2017 29(3):112-116
      PubDate: Fri,15 Sep 2017
      DOI: 10.4103/ejim.ejim_28_17
      Issue No: Vol. 29, No. 3 (2017)
       
  • Serum chemerin and diabetic retinopathy in type 2 diabetic patients

    • Authors: Alaaeldin Abdelsalam Dawood, Osama Abdalah Elmorsy, Hala Mourad Demerdash
      Pages: 117 - 121
      Abstract: Alaaeldin Abdelsalam Dawood, Osama Abdalah Elmorsy, Hala Mourad Demerdash
      The Egyptian Journal of Internal Medicine 2017 29(3):117-121
      BackgroundDiabetic retinopathy (DR) is one of the microvascular complications of type 2 diabetes mellitus (T2DM). There is a need to find a reliable screening biomarker to help in the early diagnosis of this complication.The aim of the work was to study the relation between serum chemerin and DR in T2DM patients.Patients and methodsThis study was conducted on 80 T2DM patients in addition to 20 healthy individuals who served as a control group. The participants were grouped into four groups: the T2DM group, the nonproliferative diabetic retinopathy (NPDR) group, the proliferative diabetic retinopathy (PDR) group, and the control group. Laboratory investigations were performed to all participants, which included glycosylated hemoglobin (HbA1c), serum creatinine, lipid profile, urine albumin/creatinine ratio, C-reactive protein (CRP), and serum chemerin. Fundus examination was carried out to all participants by an expert ophthalmologist.ResultsSerum chemerin was significantly higher in the PDR group compared with the other groups, in the NPDR group compared with the T2DM group and controls, and in the T2DM group compared with controls. There was a positive significant correlation between serum chemerin and BMI, HbA1c, diabetes mellitus duration, serum total cholesterol, triglycerides, low density lipoprotein, and CRP and a negative significant correlation between serum chemerin and high density lipoprotein in diabetic patients.ConclusionFrom this study, we can conclude that serum chemerin is significantly higher in patients with DR compared with diabetic patients without retinopathy and in PDR patients compared with NPDR patients. There is a positive correlation between serum chemerin and CRP, BMI, and lipid profile.
      Citation: The Egyptian Journal of Internal Medicine 2017 29(3):117-121
      PubDate: Fri,15 Sep 2017
      DOI: 10.4103/ejim.ejim_30_17
      Issue No: Vol. 29, No. 3 (2017)
       
  • B-lymphocyte stimulator: can we consider it a marker for severity of
           hepatitis C virus-induced B-cell non-Hodgkin lymphoma?

    • Authors: Yousryeia A Ahmad, Ola Afifi, Safinaz Hussein, Rania Hafez, Eman Salaheldin
      Pages: 122 - 126
      Abstract: Yousryeia A Ahmad, Ola Afifi, Safinaz Hussein, Rania Hafez, Eman Salaheldin
      The Egyptian Journal of Internal Medicine 2017 29(3):122-126
      ObjectiveB-lymphocyte stimulator (BLyS) is a member of tumor necrosis factor family. BLyS is essential for the survival of normal and malignant B lymphocyte. Hepatitis C virus (HCV) infection likely represents the early event leading to BLyS upregulation. The aim of this study was to determine the relation between serum BLyS levels and the severity of HCV-related B-cell non-Hodgkin lymphoma (B-NHL).Patients and methodsSeventy-eight B-NHL patients both HCV-positive and HCV-negative and 20 patients with HCV infection without lymphoproliferative disorders, in addition to 20 age-matched and sex-matched controls, were included in the study. PCR for HCV, evaluation of levels of soluble BLyS protein in blood, bone marrow aspirate and biopsy with flow cytometry, and lymph node biopsy with immunophenotyping for CD5, CD23, CD10, CD20, and cyclinD1 were performed.ResultsThe serum BLyS levels were significantly higher in B-NHL patients and HCV patients without lymphoproliferative disorders compared with the control group. The serum BLyS levels were statistically significantly higher in aggressive lymphoma patients with HCV-positive infection compared with aggressive lymphoma patients with HCV-negative infection, but there was no statistically significant difference between BLyS levels in indolent B-NHL patients with or without HCV infections. Moreover, there was no statistically significant difference between BLyS levels in aggressive and indolent lymphoma patients with HCV-positive infection.ConclusionBLyS levels are increased in HCV-induced B-NHL but it cannot be considered as a marker for severity of the disease (indolent or aggressive). More studies are needed.
      Citation: The Egyptian Journal of Internal Medicine 2017 29(3):122-126
      PubDate: Fri,15 Sep 2017
      DOI: 10.4103/ejim.ejim_33_17
      Issue No: Vol. 29, No. 3 (2017)
       
  • Screening of incidental kidney disease in normoglycemic, normotensive
           healthy adults

    • Authors: Ahmed Yamany, Heba Shehata, Mervat Essameldin, Salwa Ibrahim
      Pages: 127 - 131
      Abstract: Ahmed Yamany, Heba Shehata, Mervat Essameldin, Salwa Ibrahim
      The Egyptian Journal of Internal Medicine 2017 29(3):127-131
      Background and aimChronic kidney disease is a major public health problem with increased global incidence and prevalence, especially in Egypt, poor quality of life, and high risk of morbidity and mortality. The aim of the work was to determine the prevalence and the risk factors of incidental kidney diseases among apparently healthy adults.Patients and methodsA total of 300 healthy normotensive and normoglycemic individuals were assessed for creatinine, proteinuria, and glomerular filtration rate, with correlation to their BMI and systolic and diastolic blood pressures.ResultsMicroalbuminuria was positively correlated to age, BMI, and systolic blood pressure, with a significant P-value of less than 0.001.ConclusionThe prevalence estimates and risk factors for those with microalbuminuria as a marker of occult renal disease include age, BMI, high systolic blood pressure, and family history of renal problems.
      Citation: The Egyptian Journal of Internal Medicine 2017 29(3):127-131
      PubDate: Fri,15 Sep 2017
      DOI: 10.4103/ejim.ejim_35_17
      Issue No: Vol. 29, No. 3 (2017)
       
  • Brachial artery flow-mediated dilation and carotid intima-media thickness
           for assessment of subclinical atherosclerosis in rheumatoid arthritis

    • Authors: Mona Hussein El Zohri, Salwa S ELGendi, Ghada H Ahmed, Mohammed Zidan Mohammed
      Pages: 132 - 140
      Abstract: Mona Hussein El Zohri, Salwa S ELGendi, Ghada H Ahmed, Mohammed Zidan Mohammed
      The Egyptian Journal of Internal Medicine 2017 29(3):132-140
      ObjectiveThe aim of this study was to assess subclinical atherosclerosis in rheumatoid arthritis (RA) patients using flow-mediated dilation (FMD) and carotid intima–media thickness (CIMT) and find their relation to disease activity.Patients and methodsTotally, 30 RA patients without cardiac involvement and 10 controls were included in the study. Disease activity was evaluated using disease activity score 28 (DAS28) score. Low disease activity is defined by DAS28 of 3.2 or less, moderate disease activity as DAS28 3.3–5.3, and severe disease activity as DAS28 of 5.4 or more. Endothelial dysfunction is considered to be present when FMD on B-mode ultrasonography is below 4.5%. CIMT was calculated by measuring the greatest distance between lumen–intima and media–adventitia interface [mean value of two sides (right and left) was taken] using B-mode ultrasonography.ResultsThe mean CIMT was significantly higher in the RA patients (1.8±0.2) than in healthy controls (1.5±0.1) (P=0.001). Taking the mean±SD of the control group (1.6 mm) as the upper limit of the normal CIMT, 22 (73.3%) RA patients and three (30%) controls had abnormal mean CIMT, which was statistically significant. Brachial FMD% in RA patients was significantly lower (22.9±11.0) as compared with controls (35.5±23.2) (P=0.027). A statistically significant positive correlation was observed between CIMT values of patients with age, C-reactive protein, and low-density lipoprotein. There was a significant negative correlation between CIMT and hemoglobin and brachial FMD. FMD% showed a statistically significant negative correlation with age, disease duration, low-density lipoprotein, Framingham cardiovascular risk score, and mean CIMT.ConclusionCarotid ultrasound and endothelial function assessment by means of FMD may be a useful tool to predict the increased risk for cardiovascular disease in patients with RA, which requires aggressive therapy.
      Citation: The Egyptian Journal of Internal Medicine 2017 29(3):132-140
      PubDate: Fri,15 Sep 2017
      DOI: 10.4103/ejim.ejim_37_17
      Issue No: Vol. 29, No. 3 (2017)
       
  • Spontaneous lung pneumatocele in an adult with community-acquired
           pneumonia

    • Authors: Jyoti Bajpai, Surya Kant, Ajay Kumar Verma, Darshan Kumar Bajaj
      Pages: 141 - 143
      Abstract: Jyoti Bajpai, Surya Kant, Ajay Kumar Verma, Darshan Kumar Bajaj
      The Egyptian Journal of Internal Medicine 2017 29(3):141-143
      Pulmonary pneumatoceles are thin-walled, air-filled cystic lesions occurring in lung parenchyma. They occur as a sequelae to bacterial infections of the lung, especially bronchopneumonia. They are commonly seen in infants and children. In this article, we report a rare case of pneumatoceles in a 40-year-old adult following staphylococcal community-acquired pneumonia.
      Citation: The Egyptian Journal of Internal Medicine 2017 29(3):141-143
      PubDate: Fri,15 Sep 2017
      DOI: 10.4103/ejim.ejim_6_17
      Issue No: Vol. 29, No. 3 (2017)
       
  • Hodgkin’s lymphoma presenting as autoimmune hemolytic anemia

    • Authors: Sohaila Fatima, Wajih A Siddiqui, Abdulrahman Alshehri
      Pages: 144 - 146
      Abstract: Sohaila Fatima, Wajih A Siddiqui, Abdulrahman Alshehri
      The Egyptian Journal of Internal Medicine 2017 29(3):144-146
      Hodgkin’s lymphoma is a B-cell neoplasm, which usually presents with painless lymphadenopathy. Its presentation with autoimmune hemolytic anemia (AIHA) is rare, although the association of AIHA with other lymphoproliferative disorders is well known. Here, we report a case of a patient with warm AIHA who presented in a critical condition to hospital and was diagnosed with HL.
      Citation: The Egyptian Journal of Internal Medicine 2017 29(3):144-146
      PubDate: Fri,15 Sep 2017
      DOI: 10.4103/ejim.ejim_15_17
      Issue No: Vol. 29, No. 3 (2017)
       
  • Medicine in Roman and Byzantine Egypt (from 30 BC to AD 641)

    • Authors: Nevine Abd El-Gawad Ali Hasan
      Pages: 147 - 148
      Abstract: Nevine Abd El-Gawad Ali Hasan
      The Egyptian Journal of Internal Medicine 2017 29(3):147-148

      Citation: The Egyptian Journal of Internal Medicine 2017 29(3):147-148
      PubDate: Fri,15 Sep 2017
      DOI: 10.4103/ejim.ejim_46_17
      Issue No: Vol. 29, No. 3 (2017)
       
 
 
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