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Publisher: Medknow Publishers   (Total: 429 journals)

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Showing 1 - 200 of 429 Journals sorted alphabetically
Acta Medica Intl.     Open Access   (SJR: 0.101, CiteScore: 0)
Advanced Arab Academy of Audio-Vestibulogy J.     Open Access  
Advanced Biomedical Research     Open Access  
Advances in Human Biology     Open Access   (Followers: 3)
Advances in Skeletal Muscle Function Assessment     Open Access  
African J. for Infertility and Assisted Conception     Open Access  
African J. of Medical and Health Sciences     Open Access   (Followers: 2)
African J. of Paediatric Surgery     Open Access   (Followers: 7, SJR: 0.25, CiteScore: 1)
African J. of Trauma     Open Access   (Followers: 1)
Ain-Shams J. of Anaesthesiology     Open Access   (Followers: 3)
Al-Azhar Assiut Medical J.     Open Access  
Al-Basar Intl. J. of Ophthalmology     Open Access   (Followers: 1)
Alexandria J. of Pediatrics     Open Access  
Ancient Science of Life     Open Access   (Followers: 5)
Anesthesia : Essays and Researches     Open Access   (Followers: 10)
Annals of African Medicine     Open Access   (Followers: 1, SJR: 0.258, CiteScore: 1)
Annals of Bioanthropology     Open Access   (Followers: 4)
Annals of Cardiac Anaesthesia     Open Access   (Followers: 14, SJR: 0.308, CiteScore: 1)
Annals of Indian Academy of Neurology     Open Access   (Followers: 3, SJR: 0.434, CiteScore: 1)
Annals of Indian Academy of Otorhinolaryngology Head and Neck Surgery     Open Access  
Annals of Indian Psychiatry     Open Access  
Annals of Maxillofacial Surgery     Open Access   (Followers: 6)
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 9, SJR: 0.352, CiteScore: 1)
Annals of Saudi Medicine     Open Access   (SJR: 0.238, CiteScore: 1)
Annals of Thoracic Medicine     Open Access   (Followers: 6, SJR: 0.524, CiteScore: 1)
Annals of Tropical Medicine and Public Health     Open Access   (Followers: 13, SJR: 0.152, CiteScore: 0)
Annals of Tropical Pathology     Open Access  
Apollo Medicine     Open Access  
APOS Trends in Orthodontics     Open Access  
Arab J. of Interventional Radiology     Open Access  
Archives of Cardiovascular Imaging     Open Access   (Followers: 1, SJR: 0.187, CiteScore: 0)
Archives of Intl. Surgery     Open Access   (Followers: 10, SJR: 0.302, CiteScore: 1)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Archives of Medicine and Surgery     Open Access  
Archives of Pharmacy Practice     Open Access   (Followers: 6, SJR: 0.102, CiteScore: 0)
Archives of Trauma Research     Open Access   (Followers: 3, SJR: 0.37, CiteScore: 2)
Asia Pacific J. of Clinical Trials : Nervous System Diseases     Open Access  
Asia-Pacific J. of Oncology Nursing     Open Access   (Followers: 4)
Asian J. of Andrology     Open Access   (Followers: 1, SJR: 0.856, CiteScore: 2)
Asian J. of Neurosurgery     Open Access   (Followers: 2)
Asian J. of Oncology     Open Access   (Followers: 1)
Asian J. of Transfusion Science     Open Access   (Followers: 1, SJR: 0.35, CiteScore: 1)
Asian Pacific J. of Reproduction     Open Access   (SJR: 0.227, CiteScore: 1)
Asian Pacific J. of Tropical Biomedicine     Open Access   (Followers: 2, SJR: 0.491, CiteScore: 2)
Asian Pacific J. of Tropical Medicine     Open Access   (Followers: 1, SJR: 0.561, CiteScore: 2)
Astrocyte     Open Access  
Avicenna J. of Medicine     Open Access   (Followers: 1)
AYU : An international quarterly journal of research in Ayurveda     Open Access   (Followers: 6)
Benha Medical J.     Open Access  
Biomedical and Biotechnology Research J.     Open Access  
BLDE University J. of Health Sciences     Open Access  
Brain Circulation     Open Access  
Bulletin of Faculty of Physical Therapy     Open Access   (Followers: 1)
Canadian J. of Rural Medicine     Full-text available via subscription   (SJR: 0.202, CiteScore: 0)
Cancer Translational Medicine     Open Access   (Followers: 2)
Cardiology Plus     Open Access  
Chinese Medical J.     Open Access   (Followers: 10, SJR: 0.52, CiteScore: 1)
CHRISMED J. of Health and Research     Open Access   (Followers: 2)
Clinical Cancer Investigation J.     Open Access  
Clinical Dermatology Review     Open Access   (Followers: 2)
Clinical Trials in Degenerative Diseases     Open Access  
Clinical Trials in Orthopedic Disorders     Open Access  
Community Acquired Infection     Open Access  
Conservation and Society     Open Access   (Followers: 10, SJR: 0.811, CiteScore: 2)
Contemporary Clinical Dentistry     Open Access   (Followers: 4, SJR: 0.353, CiteScore: 1)
Current Medical Issues     Open Access   (Followers: 1)
CytoJ.     Open Access   (Followers: 2, SJR: 0.543, CiteScore: 1)
Delta J. of Ophthalmology     Open Access  
Dental Hypotheses     Open Access   (Followers: 3, SJR: 0.152, CiteScore: 0)
Dental Research J.     Open Access   (Followers: 11, SJR: 0.416, CiteScore: 1)
Dentistry and Medical Research     Open Access  
Digital Medicine     Open Access  
Drug Development and Therapeutics     Open Access  
Education for Health     Open Access   (Followers: 6, SJR: 0.242, CiteScore: 0)
Egyptian J. of Bronchology     Open Access  
Egyptian J. of Cardiothoracic Anesthesia     Open Access  
Egyptian J. of Cataract and Refractive Surgery     Open Access   (Followers: 1, SJR: 1.799, CiteScore: 2)
Egyptian J. of Chest Diseases and Tuberculosis     Open Access   (Followers: 3, SJR: 0.155, CiteScore: 0)
Egyptian J. of Dermatology and Venerology     Open Access   (Followers: 1)
Egyptian J. of Haematology     Open Access   (Followers: 1)
Egyptian J. of Internal Medicine     Open Access   (Followers: 1)
Egyptian J. of Neurology, Psychiatry and Neurosurgery     Open Access   (Followers: 1, SJR: 0.127, CiteScore: 0)
Egyptian J. of Obesity, Diabetes and Endocrinology     Open Access   (Followers: 1)
Egyptian J. of Otolaryngology     Open Access   (Followers: 2)
Egyptian J. of Psychiatry     Open Access   (Followers: 2)
Egyptian J. of Surgery     Open Access   (Followers: 1)
Egyptian Nursing J.     Open Access  
Egyptian Orthopaedic J.     Open Access   (Followers: 2)
Egyptian Pharmaceutical J.     Open Access  
Egyptian Retina J.     Open Access  
Egyptian Rheumatology and Rehabilitation     Open Access  
Endodontology     Open Access  
Endoscopic Ultrasound     Open Access   (SJR: 0.822, CiteScore: 2)
Environmental Disease     Open Access   (Followers: 3)
Eurasian J. of Pulmonology     Open Access  
European J. of Dentistry     Open Access   (Followers: 2, SJR: 0.749, CiteScore: 2)
European J. of General Dentistry     Open Access   (Followers: 1, SJR: 0.12, CiteScore: 0)
European J. of Prosthodontics     Open Access   (Followers: 3)
European J. of Psychology and Educational Studies     Open Access   (Followers: 11, SJR: 0.113, CiteScore: 0)
Fertility Science and Research     Open Access  
Formosan J. of Surgery     Open Access   (SJR: 0.112, CiteScore: 0)
Genome Integrity     Open Access   (Followers: 2, SJR: 0.153, CiteScore: 0)
Glioma     Open Access  
Global J. of Transfusion Medicine     Open Access   (Followers: 1)
Gynecology and Minimally Invasive Therapy     Open Access   (SJR: 0.311, CiteScore: 1)
Hamdan Medical J.     Open Access  
Heart and Mind     Open Access  
Heart India     Open Access   (Followers: 1)
Heart Views     Open Access   (Followers: 2)
Hepatitis B Annual     Open Access   (Followers: 3)
Ibnosina J. of Medicine and Biomedical Sciences     Open Access  
IJS Short Reports     Open Access  
Imam J. of Applied Sciences     Open Access  
Indian Anaesthetists Forum     Open Access  
Indian Dermatology Online J.     Open Access   (Followers: 3)
Indian J. of Allergy, Asthma and Immunology     Open Access   (Followers: 1)
Indian J. of Anaesthesia     Open Access   (Followers: 7, SJR: 0.478, CiteScore: 1)
Indian J. of Burns     Open Access   (Followers: 1)
Indian J. of Cancer     Open Access   (Followers: 1, SJR: 0.361, CiteScore: 1)
Indian J. of Cerebral Palsy     Open Access   (Followers: 1)
Indian J. of Community Medicine     Open Access   (Followers: 2, SJR: 0.37, CiteScore: 1)
Indian J. of Critical Care Medicine     Open Access   (Followers: 3, SJR: 0.604, CiteScore: 1)
Indian J. of Dental Research     Open Access   (Followers: 4, SJR: 0.266, CiteScore: 1)
Indian J. of Dental Sciences     Open Access  
Indian J. of Dentistry     Open Access   (Followers: 1)
Indian J. of Dermatology     Open Access   (Followers: 2, SJR: 0.468, CiteScore: 1)
Indian J. of Dermatology, Venereology and Leprology     Open Access   (Followers: 4, SJR: 0.445, CiteScore: 1)
Indian J. of Dermatopathology and Diagnostic Dermatology     Open Access  
Indian J. of Drugs in Dermatology     Open Access   (Followers: 1, SJR: 0.791, CiteScore: 1)
Indian J. of Endocrinology and Metabolism     Open Access   (Followers: 4, SJR: 0.568, CiteScore: 1)
Indian J. of Health Sciences     Open Access   (Followers: 2)
Indian J. of Medical and Paediatric Oncology     Open Access   (SJR: 0.425, CiteScore: 1)
Indian J. of Medical Microbiology     Open Access   (Followers: 1, SJR: 0.503, CiteScore: 1)
Indian J. of Medical Research     Open Access   (Followers: 4, SJR: 0.656, CiteScore: 1)
Indian J. of Medical Sciences     Open Access   (Followers: 2, SJR: 0.102, CiteScore: 0)
Indian J. of Multidisciplinary Dentistry     Open Access   (Followers: 1)
Indian J. of Nephrology     Open Access   (Followers: 2, SJR: 0.347, CiteScore: 1)
Indian J. of Nuclear Medicine     Open Access   (Followers: 2, SJR: 0.23, CiteScore: 0)
Indian J. of Occupational and Environmental Medicine     Open Access   (Followers: 3, SJR: 0.225, CiteScore: 1)
Indian J. of Ophthalmology     Open Access   (Followers: 4, SJR: 0.498, CiteScore: 1)
Indian J. of Oral Health and Research     Open Access  
Indian J. of Oral Sciences     Open Access   (Followers: 1)
Indian J. of Orthopaedics     Open Access   (Followers: 8, SJR: 0.392, CiteScore: 1)
Indian J. of Otology     Open Access   (Followers: 1, SJR: 0.199, CiteScore: 0)
Indian J. of Paediatric Dermatology     Open Access   (Followers: 2)
Indian J. of Pain     Open Access   (Followers: 1)
Indian J. of Palliative Care     Open Access   (Followers: 5, SJR: 0.454, CiteScore: 1)
Indian J. of Pathology and Microbiology     Open Access   (Followers: 2, SJR: 0.276, CiteScore: 1)
Indian J. of Pharmacology     Open Access   (SJR: 0.412, CiteScore: 1)
Indian J. of Plastic Surgery     Open Access   (Followers: 12, SJR: 0.311, CiteScore: 0)
Indian J. of Psychiatry     Open Access   (Followers: 3, SJR: 0.408, CiteScore: 1)
Indian J. of Psychological Medicine     Open Access   (SJR: 0.368, CiteScore: 1)
Indian J. of Public Health     Open Access   (Followers: 1)
Indian J. of Radiology and Imaging     Open Access   (Followers: 4)
Indian J. of Research in Homoeopathy     Open Access  
Indian J. of Respiratory Care     Open Access  
Indian J. of Rheumatology     Open Access   (SJR: 0.119, CiteScore: 0)
Indian J. of Sexually Transmitted Diseases and AIDS     Open Access   (Followers: 2, SJR: 0.34, CiteScore: 0)
Indian J. of Social Psychiatry     Open Access   (Followers: 2)
Indian J. of Transplantation     Open Access  
Indian J. of Urology     Open Access   (Followers: 3, SJR: 0.434, CiteScore: 1)
Indian J. of Vascular and Endovascular Surgery     Open Access   (Followers: 2)
Indian Spine J.     Open Access  
Industrial Psychiatry J.     Open Access   (Followers: 2)
Intervention     Open Access   (Followers: 1)
Intl. Archives of Health Sciences     Open Access  
Intl. J. of Abdominal Wall and Hernia Surgery     Open Access   (Followers: 1)
Intl. J. of Academic Medicine     Open Access  
Intl. J. of Advanced Medical and Health Research     Open Access  
Intl. J. of Applied and Basic Medical Research     Open Access  
Intl. J. of Clinical and Experimental Physiology     Open Access   (Followers: 1)
Intl. J. of Clinicopathological Correlation     Open Access  
Intl. J. of Community Dentistry     Open Access  
Intl. J. of Critical Illness and Injury Science     Open Access   (Followers: 1, SJR: 0.192, CiteScore: 0)
Intl. J. of Educational and Psychological Researches     Open Access   (Followers: 4)
Intl. J. of Environmental Health Engineering     Open Access   (Followers: 1)
Intl. J. of Forensic Odontology     Open Access   (Followers: 1)
Intl. J. of Green Pharmacy     Open Access   (Followers: 3, SJR: 0.142, CiteScore: 0)
Intl. J. of Growth Factors and Stem Cells in Dentistry     Open Access  
Intl. J. of Health & Allied Sciences     Open Access   (Followers: 3)
Intl. J. of Health System and Disaster Management     Open Access   (Followers: 3)
Intl. J. of Heart Rhythm     Open Access  
Intl. J. of Medicine and Public Health     Open Access   (Followers: 6)
Intl. J. of Mycobacteriology     Open Access   (SJR: 0.535, CiteScore: 1)
Intl. J. of Noncommunicable Diseases     Open Access  
Intl. J. of Nutrition, Pharmacology, Neurological Diseases     Open Access   (Followers: 4, SJR: 0.17, CiteScore: 0)
Intl. J. of Oral Health Sciences     Open Access   (Followers: 2)
Intl. J. of Orofacial Biology     Open Access   (Followers: 1)
Intl. J. of Orofacial Research     Open Access   (Followers: 1)
Intl. J. of Orthodontic Rehabilitation     Open Access  
Intl. J. of Pedodontic Rehabilitation     Open Access  
Intl. J. of Pharmaceutical Investigation     Open Access   (Followers: 1)
Intl. J. of Preventive Medicine     Open Access   (Followers: 1, SJR: 0.623, CiteScore: 1)
Intl. J. of Shoulder Surgery     Open Access   (Followers: 5, SJR: 0.653, CiteScore: 1)
Intl. J. of the Cardiovascular Academy     Open Access   (SJR: 0.105, CiteScore: 0)
Intl. J. of Trichology     Open Access   (SJR: 0.4, CiteScore: 1)
Intl. J. of Yoga     Open Access   (Followers: 15)
Intl. J. of Yoga : Philosophy, Psychology and Parapsychology     Open Access   (Followers: 6)

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Journal Cover
Egyptian Journal of Dermatology and Venerology
Number of Followers: 1  

  This is an Open Access Journal Open Access journal
ISSN (Print) 1110-6530 - ISSN (Online) 2314-7407
Published by Medknow Publishers Homepage  [429 journals]
  • Evaluation of macrophage migration inhibitory factor in patients with
           alopecia areata before and after the treatment

    • Authors: Shereen Farouk Gheida, Ghada Abdel-Moemen Soliman
      Pages: 52 - 58
      Abstract: Shereen Farouk Gheida, Ghada Abdel-Moemen Soliman
      Egyptian Journal of Dermatology and Venerology 2018 38(2):52-58
      Background Alopecia areata (AA) is a common disease affecting the anagen phase of the hair follicles. It is considered as an autoimmune disorder. Many cytokines play a role in its pathogenesis; one of these cytokines is macrophage migration inhibitory factor (MIF).Aim The aim of this study was to evaluate the MIF level to elucidate its role in the pathogenesis of AA.Patients and methods This study included 50 patients with AA and 30 normal healthy individuals who served as the control group. Serum MIF levels were evaluated by enzyme-linked immunosorbent assay in patients (before and after the treatment) and in the controls. The clinical severity of the disease was done using severity of alopecia tool scoring system and it was correlated with the serum MIF levels.Results There was a statistically significant increase in the serum MIF level in patients before the treatment, compared to the controls. In addition to this, a significant elevation in its level was found before than found after the treatment. There was a positive significant correlation between the MIF level and both duration of the disease and its clinical severity, whereas there was a negative significant correlation between MIF level and the age of the patients.Conclusion Macrophage MIF plays an important role in the etiopathogenesis of AA as it is increased in patients when compared to the controls and in patients before than after the treatment. So, it could be considered as a prognostic factor for disease severity and might be a potential new target as a future therapy.
      Citation: Egyptian Journal of Dermatology and Venerology 2018 38(2):52-58
      PubDate: Fri,17 Aug 2018
      DOI: 10.4103/ejdv.ejdv_4_18
      Issue No: Vol. 38, No. 2 (2018)
       
  • Immunohistochemical study of interleukin-31 in patients with atopic
           dermatitis

    • Authors: Tarek E Amin, Nashwa N Elfar, Fersan A Sallam
      Pages: 59 - 64
      Abstract: Tarek E Amin, Nashwa N Elfar, Fersan A Sallam
      Egyptian Journal of Dermatology and Venerology 2018 38(2):59-64
      Background Atopic dermatitis (AD) is a common chronic inflammatory skin disease of unknown etiology. Reduction of pruritus as one of the hallmarks of AD is the most effective therapeutic strategy for improving quality of life and for preventing aggravation of skin lesion. Interleukin-31 (IL-31) has been suggested to play a role in pathogenesis of AD through itch stimulation and correlation with development of pruritus.Aim The aim of this work was to study the immunohistochemical expression of IL-31 in skin lesions of patients with AD.Patients and methods The current study comprised 20 patients with AD. The severity of AD was assessed according to Six Area, Six Sign Atopic Dermatitis score. From the patients, 3-mm punch biopsy specimens were taken from lesional skin and nearby apparently normal skin to serve as control. Histopathological examination and immunohistochemical staining for IL-31 were done.Results IL-31 expression was significantly increased in lesional skin of patients with AD in comparison with nearby apparently normal skin of the same patients. IL-31 expression in the lesional skin of patients with AD showed a significant positive correlation with severity of the disease evaluated by Six Area, Six Sign Atopic Dermatitis score.Conclusion IL-31 expression was increased in the lesional skin of patients with AD compared with control specimens, and it was positively correlated with severity of AD. IL-31 may be a therapeutic target for AD and associated pruritus.
      Citation: Egyptian Journal of Dermatology and Venerology 2018 38(2):59-64
      PubDate: Fri,17 Aug 2018
      DOI: 10.4103/ejdv.ejdv_31_17
      Issue No: Vol. 38, No. 2 (2018)
       
  • Evaluation of the effectiveness of erbium
           yttrium–aluminum–garnet fractional laser, carbon dioxide
           therapy and platelet-rich plasma in treating striae distensae

    • Authors: Enas A.M. Mahrous
      Pages: 65 - 72
      Abstract: Enas A.M. Mahrous
      Egyptian Journal of Dermatology and Venerology 2018 38(2):65-72
      Objective This study aims to compare the efficiency of erbium: yttrium–aluminum–garnet (Er: YAG) laser, carboxytherapy, and platelet-4rich plasma (PRP) in the treatment of striae distensae.Background Striae distance or striae distensae are common dermal scars characterized by flattening and atrophy of the epidermis, and result in considerable aesthetic concern.Patients and methods The study was conducted on 60 female patients with striae in the area between the diaphragm and the knee, whose ages ranged between 16 and 50 years. Cases were collected from the inpatient and outpatient dermatology clinics, Shebin El-Kom Teaching Hospital, in the period from October 2016 to April 2017. Detailed history, and full general and dermatological examination were done; photography and CO2 injection were performed on 20 patients (group A), while PRP injection was done to the resting 20 (group B), and 20 patients were treated by Er: YAG laser (group C). All the potential side effects were discussed with all patients’ group prior to their participation.Results The mean age of the patients was 26.39±11.51 years. The most common sites affected by striae distensae were the abdomen, thighs and the hips. There was no significant difference regarding the patients’ skin type, duration of striae, and the result at the end of treatment sessions (P>0.05). However, there was a statistically significant difference (P<0.05) regarding the color of striae (P=0.036) and width of striae (P=0.023). Additionally, highly statistically significant (P=0.001) difference was obtained between the studied maneuvers regarding the type of pain and the modality of treatment and the improvement degree (P=0.00). The overall patient’s satisfaction after the end of the eighth session of carboxytherapy and the fourth session of PRP and the sixth session of Er: YAG laser was evaluated. The Er: YAG laser has an upper hand on carboxytherapy and PRP injection in the treatment of striae distensae regarding the results and patient’s satisfaction.Conclusion The clinical improvement of striae distensae can be obtained with the use of the Er: YAG fractional laser. The results of this study demonstrated the safety and efficacy as well as low-incidence side effects of Er: YAG fractional laser in the treatment of striae distensae as compared with CO2 and PRP. So, more randomized, controlled studies are needed to further evaluate the efficacy of lasers for the treatment of striae distensae among different skin types and different ages.
      Citation: Egyptian Journal of Dermatology and Venerology 2018 38(2):65-72
      PubDate: Fri,17 Aug 2018
      DOI: 10.4103/ejdv.ejdv_37_17
      Issue No: Vol. 38, No. 2 (2018)
       
  • Clinicoepidemiological analysis of patients with oral mucosal lesions
           attending dermatology clinics

    • Authors: Mohammed Abu El-Hamd, Soha Aboeldahab
      Pages: 73 - 79
      Abstract: Mohammed Abu El-Hamd, Soha Aboeldahab
      Egyptian Journal of Dermatology and Venerology 2018 38(2):73-79
      Background/Objectives The prevalence of oral mucosal lesions (OMLs) has a wide variety in different regions of the world. This study aimed to assess the prevalence, clinical presentations, and associated risk factors of OMLs among patients treated at Outpatient Clinics of the Dermatology, Venereology, and Andrology Department, Faculty of Medicine, Sohag University, Egypt.Patients and methods This observational study included all patients with OMLs among patients treated at the Outpatient Clinics of the Dermatology, Venereology, and Andrology Department, Faculty of Medicine, Sohag University, Egypt, from January 2016 to June 2016. Patients underwent complete history taking, and general and local oral cavity examination. The OMLs were examined and diagnosed according to the WHO 1995 criteria.Results Of the patients, 125 (2.6%) were diagnosed with different clinical types of OMLs (66 men and 59 women; mean age 28.59±14.8 years). Of these, 43 (34.4%) patients had a positive history of smoking. The most common types of OMLs were recurrent aphthous stomatitis (n=28, 22.4%), oral candidiasis (n=15, 12%), Behcet’s disease (n=12, 9.6%), recurrent herpes labialis (n=12, 9.6%), and oral lichen planus (n=7, 5.6%).Conclusion The prevalence and distribution of OMLs were elucidated at Sohag University Hospital, Upper Egypt and the importance of smoking in the pathogenesis of OMLs was evidenced.
      Citation: Egyptian Journal of Dermatology and Venerology 2018 38(2):73-79
      PubDate: Fri,17 Aug 2018
      DOI: 10.4103/ejdv.ejdv_44_17
      Issue No: Vol. 38, No. 2 (2018)
       
  • Serum interleukin-6 and interferon-&#947; in patients with leprosy

    • Authors: Essam Nada, Moustafa El Taieb, Hanan Fayed, Hasan Ibrahim, Yasmin Yasin
      Pages: 80 - 84
      Abstract: Essam Nada, Moustafa El Taieb, Hanan Fayed, Hasan Ibrahim, Yasmin Yasin
      Egyptian Journal of Dermatology and Venerology 2018 38(2):80-84
      Background Leprosy is a chronic infectious disease caused by Mycobacterium leprae and manifested by an immunological and clinical outcome, ranging from borderline lepromatous and lepromatous infections to tuberculoid and borderline tuberculoid infections. Cytokines such as interleukin (IL)-6, IL-10, interferon-γ (IFN-γ), and tumor necrosis factor-α are associated with leprosy.Objective The aim was to assess IL-6 and IFN-γ in untreated patients with leprosy and compare these levels with those in healthy controls and with different parts of the disease spectrum.Patients and methods A case–control study was conducted on 90 untreated patients with leprosy and 30 healthy controls randomly selected from patients attending the Dermatology and Leprosy Hospital, Qena Governorate, Egypt. The patients were classified into tuberculoid, borderline tuberculoid, borderline-borderline, borderline lepromatous, and lepromatous (LL). IFN-γ and IL-6 were measured by enzyme-linked immunosorbent assay technique.Results IL-6 and INF-γ were significantly higher in the patients than in the control group, with P value of 0.001 and 0.002, respectively. Regarding the serum level of INF-γ in all types of leprosy, there was a statistically significantly increase in paucibacillary leprosy and a nonsignificant increase in multibacillary leprosy; on the contrary, the results showed that serum level of IL-6 was statistically significantly increased in multibacillary leprosy and nonsignificantly increased in paucibacillary leprosy.Conclusion This study concluded that INF-γ and IL-6 may have a significant role in classifying various forms of leprosy and can be used as leprosy disease markers to predict the course and the prognosis of the disease.
      Citation: Egyptian Journal of Dermatology and Venerology 2018 38(2):80-84
      PubDate: Fri,17 Aug 2018
      DOI: 10.4103/ejdv.ejdv_45_17
      Issue No: Vol. 38, No. 2 (2018)
       
  • Effect of onychomycosis on pulse oximeter

    • Authors: Hülya Nazik, Sel&#231;uk Nazik, Feride &#199; G&#252;l, Bet&#252;l Demir, Mehmet K M&#252;layim
      Pages: 85 - 88
      Abstract: Hülya Nazik, Selçuk Nazik, Feride Ç Gül, Betül Demir, Mehmet K Mülayim
      Egyptian Journal of Dermatology and Venerology 2018 38(2):85-88
      Objective Onychomycosis causes nail thickness and discoloration of the dorsum of the nail plate. This study was aimed to investigate the effect of discoloration and nail thickness associated with onychomycosis on pulse oximetry measurement.Materials and methods The involvement degree of onychomycosis was determined using onychomycosis severity index (OSI). Two different measurements were recorded by pulse oximetry. The first one was from the nail with onychomycosis, and the second one was from the normal nail of the same hand.Results A total of 93 onychomycosis cases were included in the study. When SpO2 values of white nail color were measured, it was statistically significant higher in the onychomycosis group than the control (P<0.001). On the contrary, in the yellow nail, SpO2 values were lower in the onychomycosis group (P<0.001). Similarly in the brown nail, SpO2 values were lower in the onychomycosis group, but there was no statistically significance (P=0.083). It was determined that there was no statistically significant difference between SpO2 values and OSI (P=0.563).Conclusion As a result, SpO2 values were affected by discoloration owing to onychomycosis. SpO2 values were found lower in patients with moderate and severe OSI, which is related to nail thickness than the control. It was concluded that the discoloration and nail thickness associated with onychomycosis were effective on pulse oximetry measurement.
      Citation: Egyptian Journal of Dermatology and Venerology 2018 38(2):85-88
      PubDate: Fri,17 Aug 2018
      DOI: 10.4103/ejdv.ejdv_9_18
      Issue No: Vol. 38, No. 2 (2018)
       
  • A case of hyperkeratotic cutaneous leishmaniasis on the hallux: an unusual
           presentation of American tegumentary leishmaniasis

    • Authors: Marcus H. de S.B Xavier, Sabha Mushtaq, Luiz A.B P&#244;rto, Ana C.R Fonseca, Mois&#233;s S Pedrosa
      Pages: 89 - 91
      Abstract: Marcus H. de S.B Xavier, Sabha Mushtaq, Luiz A.B Pôrto, Ana C.R Fonseca, Moisés S Pedrosa
      Egyptian Journal of Dermatology and Venerology 2018 38(2):89-91
      Cutaneous leishmaniasis (CL) is endemic in various parts of Brazil and is known for its clinical pleiomorphism in humans. Beyond the classical picture, CL may appear at unusual sites or with atypical morphologies which may elude the diagnosis at first instance. Herein, we report the case of a 48-year-old Brazilian male, who presented with a 2-year history of persistent hyperkeratotic plaque on the left hallux, which turned out to be cutaneous leishmaniasis. The wide variety of cutaneous findings and unusual presentations of CL often pose a diagnostic challenge especially for inexperienced physicians. The objective of this case report is to emphasize on the unpredictability of clinical expressions of CL and to apprise the clinicians of its masquerading potential.
      Citation: Egyptian Journal of Dermatology and Venerology 2018 38(2):89-91
      PubDate: Fri,17 Aug 2018
      DOI: 10.4103/ejdv.ejdv_12_18
      Issue No: Vol. 38, No. 2 (2018)
       
  • Becker&#8217;s nevus on face with asymmetric hair growth and acne:
           a rare case

    • Authors: Riti Acharya, Jayamani Shrestha
      Pages: 92 - 94
      Abstract: Riti Acharya, Jayamani Shrestha
      Egyptian Journal of Dermatology and Venerology 2018 38(2):92-94
      Becker’s nevus (BN), a cutaneous hamartoma, is usually seen in the upper half of the trunk during puberty. Location of BN at other sites is an exception. The theory of somatic mosaicism and androgen sensitivity supports the origin and characteristics of BN. Here, we report an interesting and unusual case of BN on face with asymmetric growth of beard and acne on the same with complete absence of hair on other side of the face. The author aims to highlight a rare clinical presentation of common condition and the first of its kind from Nepal.
      Citation: Egyptian Journal of Dermatology and Venerology 2018 38(2):92-94
      PubDate: Fri,17 Aug 2018
      DOI: 10.4103/ejdv.ejdv_7_18
      Issue No: Vol. 38, No. 2 (2018)
       
  • Ichthyosis and severe acute malnutrition

    • Authors: Ibrahim Aliyu, Sani Mado
      Pages: 95 - 96
      Abstract: Ibrahim Aliyu, Sani Mado
      Egyptian Journal of Dermatology and Venerology 2018 38(2):95-96
      Ichthyosis is a cutaneous disorder characterized by hyperkeratosis of the skin. It is mostly congenital; however, acquired cases have been reported in patients with severe malnutrition. Furthermore, congenital ichthyosis has been associated with micronutrient deficiency such as vitamin D deficiency, resulting in rickets in ∼41% of cases. The two cases reported in this communication were 12 and 11 months old, correspondingly, with congenital lamellar ichthyosis. They had similarly feeding pattern and absence of family history of malnutrition in other siblings, but they developed severe acute malnutrition. The association of congenital ichthyosis with severe acute malnutrition is poorly understood; however, malnutrition has been reported to cause acquired ichthyosis.
      Citation: Egyptian Journal of Dermatology and Venerology 2018 38(2):95-96
      PubDate: Fri,17 Aug 2018
      DOI: 10.4103/ejdv.ejdv_42_17
      Issue No: Vol. 38, No. 2 (2018)
       
  • Erratum: Role of prolactin in activity of systemic lupus erythematosus

    • Pages: 97 - 97
      Abstract:
      Egyptian Journal of Dermatology and Venerology 2018 38(2):97-97

      Citation: Egyptian Journal of Dermatology and Venerology 2018 38(2):97-97
      PubDate: Fri,17 Aug 2018
      DOI: 10.4103/1110-6530.239209
      Issue No: Vol. 38, No. 2 (2018)
       
 
 
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