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Publisher: Medknow Publishers   (Total: 429 journals)

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Showing 1 - 200 of 429 Journals sorted alphabetically
Acta Medica Intl.     Open Access   (SJR: 0.101, CiteScore: 0)
Advanced Arab Academy of Audio-Vestibulogy J.     Open Access  
Advanced Biomedical Research     Open Access  
Advances in Human Biology     Open Access   (Followers: 3)
Advances in Skeletal Muscle Function Assessment     Open Access  
African J. for Infertility and Assisted Conception     Open Access  
African J. of Medical and Health Sciences     Open Access   (Followers: 2)
African J. of Paediatric Surgery     Open Access   (Followers: 7, SJR: 0.25, CiteScore: 1)
African J. of Trauma     Open Access   (Followers: 1)
Ain-Shams J. of Anaesthesiology     Open Access   (Followers: 3)
Al-Azhar Assiut Medical J.     Open Access  
Al-Basar Intl. J. of Ophthalmology     Open Access   (Followers: 1)
Alexandria J. of Pediatrics     Open Access  
Ancient Science of Life     Open Access   (Followers: 5)
Anesthesia : Essays and Researches     Open Access   (Followers: 10)
Annals of African Medicine     Open Access   (Followers: 1, SJR: 0.258, CiteScore: 1)
Annals of Bioanthropology     Open Access   (Followers: 4)
Annals of Cardiac Anaesthesia     Open Access   (Followers: 14, SJR: 0.308, CiteScore: 1)
Annals of Indian Academy of Neurology     Open Access   (Followers: 3, SJR: 0.434, CiteScore: 1)
Annals of Indian Academy of Otorhinolaryngology Head and Neck Surgery     Open Access  
Annals of Indian Psychiatry     Open Access  
Annals of Maxillofacial Surgery     Open Access   (Followers: 6)
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 7, SJR: 0.352, CiteScore: 1)
Annals of Saudi Medicine     Open Access   (SJR: 0.238, CiteScore: 1)
Annals of Thoracic Medicine     Open Access   (Followers: 5, SJR: 0.524, CiteScore: 1)
Annals of Tropical Medicine and Public Health     Open Access   (Followers: 12, SJR: 0.152, CiteScore: 0)
Annals of Tropical Pathology     Open Access  
Apollo Medicine     Open Access  
APOS Trends in Orthodontics     Open Access  
Arab J. of Interventional Radiology     Open Access  
Archives of Cardiovascular Imaging     Open Access   (Followers: 1, SJR: 0.187, CiteScore: 0)
Archives of Intl. Surgery     Open Access   (Followers: 10, SJR: 0.302, CiteScore: 1)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Archives of Medicine and Surgery     Open Access  
Archives of Pharmacy Practice     Open Access   (Followers: 6, SJR: 0.102, CiteScore: 0)
Archives of Trauma Research     Open Access   (Followers: 3, SJR: 0.37, CiteScore: 2)
Asia Pacific J. of Clinical Trials : Nervous System Diseases     Open Access  
Asia-Pacific J. of Oncology Nursing     Open Access   (Followers: 4)
Asian J. of Andrology     Open Access   (Followers: 1, SJR: 0.856, CiteScore: 2)
Asian J. of Neurosurgery     Open Access   (Followers: 2)
Asian J. of Oncology     Open Access   (Followers: 1)
Asian J. of Transfusion Science     Open Access   (Followers: 1, SJR: 0.35, CiteScore: 1)
Asian Pacific J. of Reproduction     Open Access   (SJR: 0.227, CiteScore: 1)
Asian Pacific J. of Tropical Biomedicine     Open Access   (Followers: 2, SJR: 0.491, CiteScore: 2)
Asian Pacific J. of Tropical Medicine     Open Access   (Followers: 1, SJR: 0.561, CiteScore: 2)
Astrocyte     Open Access  
Avicenna J. of Medicine     Open Access   (Followers: 1)
AYU : An international quarterly journal of research in Ayurveda     Open Access   (Followers: 6)
Benha Medical J.     Open Access  
Biomedical and Biotechnology Research J.     Open Access  
BLDE University J. of Health Sciences     Open Access  
Brain Circulation     Open Access  
Bulletin of Faculty of Physical Therapy     Open Access   (Followers: 1)
Canadian J. of Rural Medicine     Full-text available via subscription   (SJR: 0.202, CiteScore: 0)
Cancer Translational Medicine     Open Access   (Followers: 2)
Cardiology Plus     Open Access  
Chinese Medical J.     Open Access   (Followers: 10, SJR: 0.52, CiteScore: 1)
CHRISMED J. of Health and Research     Open Access  
Clinical Cancer Investigation J.     Open Access  
Clinical Dermatology Review     Open Access   (Followers: 2)
Clinical Trials in Degenerative Diseases     Open Access  
Clinical Trials in Orthopedic Disorders     Open Access  
Community Acquired Infection     Open Access  
Conservation and Society     Open Access   (Followers: 10, SJR: 0.811, CiteScore: 2)
Contemporary Clinical Dentistry     Open Access   (Followers: 4, SJR: 0.353, CiteScore: 1)
Current Medical Issues     Open Access   (Followers: 1)
CytoJ.     Open Access   (Followers: 2, SJR: 0.543, CiteScore: 1)
Delta J. of Ophthalmology     Open Access  
Dental Hypotheses     Open Access   (Followers: 3, SJR: 0.152, CiteScore: 0)
Dental Research J.     Open Access   (Followers: 11, SJR: 0.416, CiteScore: 1)
Dentistry and Medical Research     Open Access  
Digital Medicine     Open Access  
Drug Development and Therapeutics     Open Access  
Education for Health     Open Access   (Followers: 6, SJR: 0.242, CiteScore: 0)
Egyptian J. of Bronchology     Open Access  
Egyptian J. of Cardiothoracic Anesthesia     Open Access  
Egyptian J. of Cataract and Refractive Surgery     Open Access   (Followers: 1, SJR: 1.799, CiteScore: 2)
Egyptian J. of Chest Diseases and Tuberculosis     Open Access   (Followers: 3, SJR: 0.155, CiteScore: 0)
Egyptian J. of Dermatology and Venerology     Open Access   (Followers: 1)
Egyptian J. of Haematology     Open Access   (Followers: 1)
Egyptian J. of Internal Medicine     Open Access   (Followers: 1)
Egyptian J. of Neurology, Psychiatry and Neurosurgery     Open Access   (Followers: 1, SJR: 0.127, CiteScore: 0)
Egyptian J. of Obesity, Diabetes and Endocrinology     Open Access  
Egyptian J. of Otolaryngology     Open Access   (Followers: 2)
Egyptian J. of Psychiatry     Open Access   (Followers: 2)
Egyptian J. of Surgery     Open Access   (Followers: 1)
Egyptian Nursing J.     Open Access  
Egyptian Orthopaedic J.     Open Access   (Followers: 2)
Egyptian Pharmaceutical J.     Open Access  
Egyptian Retina J.     Open Access  
Egyptian Rheumatology and Rehabilitation     Open Access  
Endodontology     Open Access  
Endoscopic Ultrasound     Open Access   (SJR: 0.822, CiteScore: 2)
Environmental Disease     Open Access   (Followers: 2)
Eurasian J. of Pulmonology     Open Access  
European J. of Dentistry     Open Access   (Followers: 2, SJR: 0.749, CiteScore: 2)
European J. of General Dentistry     Open Access   (Followers: 1, SJR: 0.12, CiteScore: 0)
European J. of Prosthodontics     Open Access   (Followers: 3)
European J. of Psychology and Educational Studies     Open Access   (Followers: 11, SJR: 0.113, CiteScore: 0)
Fertility Science and Research     Open Access  
Formosan J. of Surgery     Open Access   (SJR: 0.112, CiteScore: 0)
Genome Integrity     Open Access   (Followers: 3, SJR: 0.153, CiteScore: 0)
Glioma     Open Access  
Global J. of Transfusion Medicine     Open Access   (Followers: 1)
Gynecology and Minimally Invasive Therapy     Open Access   (SJR: 0.311, CiteScore: 1)
Hamdan Medical J.     Open Access  
Heart and Mind     Open Access  
Heart India     Open Access   (Followers: 1)
Heart Views     Open Access   (Followers: 2)
Hepatitis B Annual     Open Access   (Followers: 3)
Ibnosina J. of Medicine and Biomedical Sciences     Open Access  
IJS Short Reports     Open Access  
Imam J. of Applied Sciences     Open Access  
Indian Anaesthetists Forum     Open Access  
Indian Dermatology Online J.     Open Access   (Followers: 3)
Indian J. of Allergy, Asthma and Immunology     Open Access   (Followers: 1)
Indian J. of Anaesthesia     Open Access   (Followers: 7, SJR: 0.478, CiteScore: 1)
Indian J. of Burns     Open Access   (Followers: 1)
Indian J. of Cancer     Open Access   (Followers: 1, SJR: 0.361, CiteScore: 1)
Indian J. of Cerebral Palsy     Open Access   (Followers: 1)
Indian J. of Community Medicine     Open Access   (Followers: 2, SJR: 0.37, CiteScore: 1)
Indian J. of Critical Care Medicine     Open Access   (Followers: 2, SJR: 0.604, CiteScore: 1)
Indian J. of Dental Research     Open Access   (Followers: 4, SJR: 0.266, CiteScore: 1)
Indian J. of Dental Sciences     Open Access  
Indian J. of Dentistry     Open Access   (Followers: 1)
Indian J. of Dermatology     Open Access   (Followers: 2, SJR: 0.468, CiteScore: 1)
Indian J. of Dermatology, Venereology and Leprology     Open Access   (Followers: 5, SJR: 0.445, CiteScore: 1)
Indian J. of Dermatopathology and Diagnostic Dermatology     Open Access  
Indian J. of Drugs in Dermatology     Open Access   (Followers: 1, SJR: 0.791, CiteScore: 1)
Indian J. of Endocrinology and Metabolism     Open Access   (Followers: 4, SJR: 0.568, CiteScore: 1)
Indian J. of Health Sciences     Open Access   (Followers: 3)
Indian J. of Medical and Paediatric Oncology     Open Access   (SJR: 0.425, CiteScore: 1)
Indian J. of Medical Microbiology     Open Access   (Followers: 1, SJR: 0.503, CiteScore: 1)
Indian J. of Medical Research     Open Access   (Followers: 4, SJR: 0.656, CiteScore: 1)
Indian J. of Medical Sciences     Open Access   (Followers: 2, SJR: 0.102, CiteScore: 0)
Indian J. of Multidisciplinary Dentistry     Open Access   (Followers: 1)
Indian J. of Nephrology     Open Access   (Followers: 2, SJR: 0.347, CiteScore: 1)
Indian J. of Nuclear Medicine     Open Access   (Followers: 2, SJR: 0.23, CiteScore: 0)
Indian J. of Occupational and Environmental Medicine     Open Access   (Followers: 3, SJR: 0.225, CiteScore: 1)
Indian J. of Ophthalmology     Open Access   (Followers: 4, SJR: 0.498, CiteScore: 1)
Indian J. of Oral Health and Research     Open Access  
Indian J. of Oral Sciences     Open Access   (Followers: 1)
Indian J. of Orthopaedics     Open Access   (Followers: 8, SJR: 0.392, CiteScore: 1)
Indian J. of Otology     Open Access   (Followers: 1, SJR: 0.199, CiteScore: 0)
Indian J. of Paediatric Dermatology     Open Access   (Followers: 2)
Indian J. of Pain     Open Access   (Followers: 1)
Indian J. of Palliative Care     Open Access   (Followers: 5, SJR: 0.454, CiteScore: 1)
Indian J. of Pathology and Microbiology     Open Access   (Followers: 2, SJR: 0.276, CiteScore: 1)
Indian J. of Pharmacology     Open Access   (SJR: 0.412, CiteScore: 1)
Indian J. of Plastic Surgery     Open Access   (Followers: 12, SJR: 0.311, CiteScore: 0)
Indian J. of Psychiatry     Open Access   (Followers: 3, SJR: 0.408, CiteScore: 1)
Indian J. of Psychological Medicine     Open Access   (SJR: 0.368, CiteScore: 1)
Indian J. of Public Health     Open Access   (Followers: 1)
Indian J. of Radiology and Imaging     Open Access   (Followers: 4)
Indian J. of Research in Homoeopathy     Open Access  
Indian J. of Respiratory Care     Open Access  
Indian J. of Rheumatology     Open Access   (SJR: 0.119, CiteScore: 0)
Indian J. of Sexually Transmitted Diseases and AIDS     Open Access   (Followers: 2, SJR: 0.34, CiteScore: 0)
Indian J. of Social Psychiatry     Open Access   (Followers: 2)
Indian J. of Transplantation     Open Access  
Indian J. of Urology     Open Access   (Followers: 3, SJR: 0.434, CiteScore: 1)
Indian J. of Vascular and Endovascular Surgery     Open Access   (Followers: 2)
Indian Spine J.     Open Access  
Industrial Psychiatry J.     Open Access   (Followers: 2)
Intervention     Open Access   (Followers: 1)
Intl. Archives of Health Sciences     Open Access  
Intl. J. of Abdominal Wall and Hernia Surgery     Open Access  
Intl. J. of Academic Medicine     Open Access  
Intl. J. of Advanced Medical and Health Research     Open Access  
Intl. J. of Applied and Basic Medical Research     Open Access  
Intl. J. of Clinical and Experimental Physiology     Open Access   (Followers: 1)
Intl. J. of Clinicopathological Correlation     Open Access  
Intl. J. of Community Dentistry     Open Access  
Intl. J. of Critical Illness and Injury Science     Open Access   (Followers: 1, SJR: 0.192, CiteScore: 0)
Intl. J. of Educational and Psychological Researches     Open Access   (Followers: 4)
Intl. J. of Environmental Health Engineering     Open Access   (Followers: 1)
Intl. J. of Forensic Odontology     Open Access   (Followers: 1)
Intl. J. of Green Pharmacy     Open Access   (Followers: 3, SJR: 0.142, CiteScore: 0)
Intl. J. of Growth Factors and Stem Cells in Dentistry     Open Access  
Intl. J. of Health & Allied Sciences     Open Access   (Followers: 3)
Intl. J. of Health System and Disaster Management     Open Access   (Followers: 3)
Intl. J. of Heart Rhythm     Open Access  
Intl. J. of Medicine and Public Health     Open Access   (Followers: 6)
Intl. J. of Mycobacteriology     Open Access   (SJR: 0.535, CiteScore: 1)
Intl. J. of Noncommunicable Diseases     Open Access  
Intl. J. of Nutrition, Pharmacology, Neurological Diseases     Open Access   (Followers: 4, SJR: 0.17, CiteScore: 0)
Intl. J. of Oral Health Sciences     Open Access   (Followers: 2)
Intl. J. of Orofacial Biology     Open Access  
Intl. J. of Orofacial Research     Open Access  
Intl. J. of Orthodontic Rehabilitation     Open Access  
Intl. J. of Pedodontic Rehabilitation     Open Access  
Intl. J. of Pharmaceutical Investigation     Open Access   (Followers: 1)
Intl. J. of Preventive Medicine     Open Access   (Followers: 1, SJR: 0.623, CiteScore: 1)
Intl. J. of Shoulder Surgery     Open Access   (Followers: 5, SJR: 0.653, CiteScore: 1)
Intl. J. of the Cardiovascular Academy     Open Access   (SJR: 0.105, CiteScore: 0)
Intl. J. of Trichology     Open Access   (SJR: 0.4, CiteScore: 1)
Intl. J. of Yoga     Open Access   (Followers: 13)
Intl. J. of Yoga : Philosophy, Psychology and Parapsychology     Open Access   (Followers: 5)

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Journal Cover
Egyptian Journal of Chest Diseases and Tuberculosis
Journal Prestige (SJR): 0.155
Number of Followers: 3  

  This is an Open Access Journal Open Access journal
ISSN (Print) 0422-7638 - ISSN (Online) 2090-9950
Published by Medknow Publishers Homepage  [429 journals]
  • Vocal cord dysfunction: an often misdiagnosed condition

    • Authors: Hossam E.M Abdel-Hamid
      Pages: 1 - 3
      Abstract: Hossam E.M Abdel-Hamid
      The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):1-3
      Vocal cord dysfunction (VCD) is the abnormal adduction of the vocal cords during inspiration or expiration that results in varying degrees of airway obstruction. VCD is more common in female patients and usually presents during childhood or adolescence and continues up to age 40 years. Studies have found an increased prevalence of VCD in female athletes and academic high-achievers compared with the general population. VCD is often misdiagnosed as asthma or exercise-induced bronchospasms because of similarities in clinical presentation. As misdiagnosis results in inappropriate pharmacotherapy, it is important for the pharmacist to have a thorough understanding of VCD to differentiate it from asthma and exercise-induced bronchospasms.
      Citation: The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):1-3
      PubDate: Wed,21 Mar 2018
      DOI: 10.4103/ejcdt.ejcdt_12_18
      Issue No: Vol. 67, No. 1 (2018)
       
  • Vocal cord dysfunction: an often misdiagnosed condition

    • Authors: Hossam E.M Abdel-Hamid
      Pages: 1 - 3
      Abstract: Hossam E.M Abdel-Hamid
      The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):1-3
      Vocal cord dysfunction (VCD) is the abnormal adduction of the vocal cords during inspiration or expiration that results in varying degrees of airway obstruction. VCD is more common in female patients and usually presents during childhood or adolescence and continues up to age 40 years. Studies have found an increased prevalence of VCD in female athletes and academic high-achievers compared with the general population. VCD is often misdiagnosed as asthma or exercise-induced bronchospasms because of similarities in clinical presentation. As misdiagnosis results in inappropriate pharmacotherapy, it is important for the pharmacist to have a thorough understanding of VCD to differentiate it from asthma and exercise-induced bronchospasms.
      Citation: The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):1-3
      PubDate: Wed,21 Mar 2018
      DOI: 10.4103/ejcdt.ejcdt_12_18
      Issue No: Vol. 67, No. 1 (2018)
       
  • Role of serum periostin as a biomarker in diagnosis of bronchial asthma

    • Authors: Dina R Mohammed, Amira Y Abdelnaby, Enas A El Zamran, Ibrahim S Ibrahim
      Pages: 4 - 8
      Abstract: Dina R Mohammed, Amira Y Abdelnaby, Enas A El Zamran, Ibrahim S Ibrahim
      The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):4-8
      Background Asthma is a chronic airway disease that is characterized by persistant airway inflammation and remoldeing with bronchial hyperactivity in resulted from one allergen or more leading to episodic airflow obstruction. Periostin can be detected in serum of asthmapatients which largly reflected to its level production in airway. Periostin is secreted by airway epithlialcellin response to iL-13 stimulation and easly leak into the airway capillary. Serum periostin could be aperdector ofairway esinophilliato patients with severeasthma.Aim of the work Is estimating the serum periostin level in patients with bronchial asthma to evaluate its role in diagnosis.Methodology This study was carried out on 25 normal healthy individual serveing as control (Group I), 25 patients diagnosed as atopic asthmatic patient regarding to skin prick test (its postive>3) (Group II) and 25 patients diagnosed as non-atopic asthmatic patient regarding to skin prick test (its negative <3) (Group III). Informed consent was taken from all patients and controls. Patient was submitted to full History taking, Clinical evaluation, Chest X-ray, Pulmonary function tests, Skin prick test to inhalant allergens and laboratory investigations including (CBC and Serum levels of periostin were assayed using an enzyme-linked immunosorbent assay (ELISA).Results Statistical analysis of the results of present work showed that serum periostin was significantly higher in asthmatic group (atopic and non atopic) in comparison to control group. Serum perioestin was also significantly higher in group 11 (atopic asthma) than group 111 (non atopic asthma) as cutting off was>420 and sensitivity and specifity was 40.0, 100.0 resepctivily.Conclusion Serum periostin can be used in dignosis of asthma and differntiation of atopic asthma from non atopic asthma.
      Citation: The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):4-8
      PubDate: Wed,21 Mar 2018
      DOI: 10.4103/ejcdt.ejcdt_4_17
      Issue No: Vol. 67, No. 1 (2018)
       
  • Retinal vascular tortuosity in patients with obstructive sleep
           apnea-chronic obstructive pulmonary disease overlap syndrome

    • Authors: Rabab A El Wahsh, Maha Yousif, Asmaa M Ibrahim
      Pages: 9 - 16
      Abstract: Rabab A El Wahsh, Maha Yousif, Asmaa M Ibrahim
      The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):9-16
      Background Obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD) are linked with microvascular changes. Retinal microvasculature can be examined in a direct noninvasive way.Aim The aim was to evaluate tortuosity of the retinal vessels in patients with COPD, OSA, and overlap syndrome.Patients and methods A total of 60 participants were included: 15 patients with OSA, 15 patients with COPD, 15 patients with COPD-OSA overlap syndrome, and 15 matched controls. All participants underwent digital retinal photography, polysomnography, arterial blood gases, spirometry, Epworth sleepiness scale, and STOP-BANG questionnaires.Results Tortuosity of most retinal vessels was higher in all patient groups when compared with the control group, and tortuosity was more marked in the overlap syndrome group. There was a negative correlation between tortuosity of retinal vessels and PO2, O2 saturation, and minimum O2 saturation, and a positive correlation with PCO2, apnea hypopnea index, O2 desaturation index, BMI, and smoking index.Conclusion Retinal vascular tortuosity occurs in OSA, COPD, and overlap syndrome. Retinal vascular tortuosity is correlated with arterial blood gases parameters, polysomnographic findings, smoking index, and BMI.
      Citation: The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):9-16
      PubDate: Wed,21 Mar 2018
      DOI: 10.4103/ejcdt.ejcdt_5_17
      Issue No: Vol. 67, No. 1 (2018)
       
  • Vitamin D deficiency in chronic obstructive pulmonary disease and
           bronchogenic carcinoma

    • Authors: Yasmine H El-Hinnawy, Youssef M.A Soliman, Radwa M.A Halim
      Pages: 17 - 20
      Abstract: Yasmine H El-Hinnawy, Youssef M.A Soliman, Radwa M.A Halim
      The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):17-20
      Rationale Vitamin D has been known to have an important role as an anti-inflammatory agent and immune modulator. The aim of this work was to evaluate the impact of vitamin D deficiency on chronic obstructive pulmonary disease (COPD) and bronchogenic carcinoma.Patients and methods The study population consisted of 58 patients. All were male patients and were divided into two groups: group A consisted of patients with COPD (n=30) [diagnosed by history, examination and pulmonary function testing and further evaluated by BMI, 6 min walk test and oxygen saturation by pulse oximeter (SpO2)] and group B (n=28) consisted of patients with bronchogenic carcinoma not having COPD (diagnosed by history, examination, pulmonary function testing to exclude COPD, computed tomography chest and biopsy, which was obtained through fibreoptic bronchoscopy, ultrasound guided or computed tomography guided). All were tested for 25-OH vitamin D3/D2.Results The relation between vitamin D deficiency and COPD severity was studied, revealing no statistically significant correlation. The relation between vitamin D deficiency and bronchogenic carcinoma revealed a statistically significant correlation. Although vitamin D deficiency was not statistically significant among different histological types of bronchogenic carcinoma, vitamin D level (mean±SD: 53.15±17.61) was higher in squamous cell carcinoma than that found in small cell cancer (30.32±14.83) and adenocarcinoma (22.75±8.67).Conclusion Vitamin D deficiency has been known to have an impact on the respiratory system. We were not able to find a relation linking COPD to vitamin D deficiency. However vitamin D deficiency seemed to be more related to the development of bronchogenic carcinoma. Although the type of bronchogenic carcinoma did not show statistical significance regarding deficiency of vitamin D. Squamous cell carcinoma patients didn’t show deficiency in contrast to other types. Vitamin D deficiency seemed related to bronchogenic carcinoma more than it is to COPD.
      Citation: The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):17-20
      PubDate: Wed,21 Mar 2018
      DOI: 10.4103/ejcdt.ejcdt_7_17
      Issue No: Vol. 67, No. 1 (2018)
       
  • Utility of bone marrow mononuclear cells as a novel therapy in chronic
           obstructive pulmonary diseases

    • Authors: Ibrahim S Ibrahim, Mohamed S Hantera, Amira Y Abdelnaby
      Pages: 21 - 25
      Abstract: Ibrahim S Ibrahim, Mohamed S Hantera, Amira Y Abdelnaby
      The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):21-25
      Background Stem cells have undifferentiated cells that have can proliferate to one or more cells. Exogenous stem cells derived from embryonic and adult tissues could be used in the regeneration of diseased organs, including lung and tissue. Chronic obstructive pulmonary disease (COPD) pathogenesis plays a major role in the upregulation of inflammation, making irreversible procedure, like apoptosis of cells, lysis of the components of extracellular matrix in lung. All treatments of COPD to date have involved pharmacological therapy and mainly target the symptoms; hence, there is an urgent need for novel and more effective therapeutic strategies. Mesenchymal stem cells are considered a therapy in COPD more for their immune modulatory effects.Aim This study aimed to evaluate the effect of stem cell therapy on mild-to-moderate COPD patients, either by infusion or by inhalation, on the basis of pulmonary function tests and quality of life.Patients and methods This study was carried out on 30 patients with COPD divided into three groups: 10 patients received COPD medication alone according to the Global Initiative for Chronic Obstructive Lung Disease guidelines (long-acting B2 agonist and inhaled corticosteroids) as a control group, 10 patients received COPD medication plus stem cell infusion, and 10 patients received COPD medication plus stem cell inhalation. Pulmonary functions tests were performed and the quality of life was determined in all patient groups.Results The pulmonary functions tests showed an insignificant increase in mild-to-moderate COPD patients after 1 month of stem cell, both by infusion and by inhalation, but there was a significant increase in the quality of life with the use of both methods of stem cell treatment compared with the control group.Conclusion Stem cell therapy leads to significant improvements in the quality of life of patients with mild-to-moderate COPD.
      Citation: The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):21-25
      PubDate: Wed,21 Mar 2018
      DOI: 10.4103/ejcdt.ejcdt_3_17
      Issue No: Vol. 67, No. 1 (2018)
       
  • Noninvasive ventilation with add-on fiberoptic bronchoscopy in patients
           with chronic obstructive pulmonary disease

    • Authors: Ahmed Sh Mohamed, Dalia E El-Sharawy
      Pages: 26 - 31
      Abstract: Ahmed Sh Mohamed, Dalia E El-Sharawy
      The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):26-31
      Introduction Noninvasive ventilation (NIV) is a valuable treatment for acute respiratory failure, which has many advantages and lessens the risk of tracheal intubation with its associated complications. Retained bronchial secretions are one of the most common causes of NIV failure and even can contraindicate its use.Aim The aim was to assess the therapeutic utility of fiberoptic bronchoscopy as an add-on therapy in patients with acute respiratory failure on NIV, in a trial to decrease the possibility of invasive ventilation.Patients and methods Patients with COPD were divided randomly into two groups: group I (20 patients) was subjected to NIV and medical therapy, and group II (20 patients) was subjected to NIV, medical therapy, and fiberoptic bronchoscopy for suctioning the retained secretions while on NIV. The cardiorespiratory parameters and complications were recorded during and after the procedure.Results A total of 26 (65%) male and 14 (35%) female patients were enrolled in the study, with mean age of 47.55±11.56 years (range: 27–68 years). The mean duration of bronchoscopy was 3.5–7 min (range: 5.2±1.2 min) with no major complications. The amount of the aspirated secretions was 17.55±5.96 ml (range: 9–29 ml). There was significant difference on follow-up between the two groups regarding mean pH, PaO2/FiO2, and PaCO2, with more obvious improvement in group II than group I and with better outcome.Conclusion Bronchoscopy on NIV in patients with COPD with acute respiratory failure and copious bronchial secretions can be an alternative to intubation with all its associated risks.
      Citation: The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):26-31
      PubDate: Wed,21 Mar 2018
      DOI: 10.4103/ejcdt.ejcdt_27_17
      Issue No: Vol. 67, No. 1 (2018)
       
  • Prevalence and first-line drug sensitivity trends of Mycobacterium
           tuberculosis at a tertiary center in North-East India

    • Authors: Amit Banik, Niladrisekhar Das, Valarie Wihiwot Lyngdoh, Anil Chandra Phukan, Vikramjeet Dutta
      Pages: 32 - 37
      Abstract: Amit Banik, Niladrisekhar Das, Valarie Wihiwot Lyngdoh, Anil Chandra Phukan, Vikramjeet Dutta
      The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):32-37
      Setting Tuberculosis (TB) still remains one of the major health problems facing humans. India accounts for almost a quarter of TB cases worldwide. The scenario is worsening owing to multidrug resistant-tuberculosis (MDR-TB). Assessment of local prevalence rates and detection of MDR-TB are important to rationalize therapy and prevent spread of resistant strains in community.Objective The study was undertaken to understand drug sensitivity patterns of tubercle bacillus and assess resistance trends in Meghalaya.Designs Specimens were screened for acid-fast bacilli, decontaminated by N-acetyl cysteine–sodium hydroxide method, and subsequently inoculated onto Lowenstein–Jensen media. Characteristic growth was biochemically identified as TB bacillus. Drug sensitivity assessment to first-line anti-TB drugs was performed by proportion method and sensitivity patterns noted.Results Among 103 specimens received, 23 showed acid-fast bacilli. Male to female ratio was 3 : 2. Fourteen (13.6%) pure isolates of Mycobacterium spp. were obtained. Biochemically 10 isolates were confirmed as M. tuberculosis. Drug sensitivity profile revealed highest mono resistance to isoniazid and streptomycin. Two (20%) isolates were MDR.Conclusion The study gives a brief overview of the menace of TB in Meghalaya. The study results provide valuable information about presence of primary MDR-TB and provide basis for future larger field surveys.
      Citation: The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):32-37
      PubDate: Wed,21 Mar 2018
      DOI: 10.4103/ejcdt.ejcdt_28_17
      Issue No: Vol. 67, No. 1 (2018)
       
  • The role of ultrasound-guided nephrostomy catheter drainage in the
           management of peripheral pyogenic lung abscess

    • Authors: Amira A Gaballah, Alaa Eldin M Elgazzar, Hanan M Elshahat, Abdul Raheem I Yusuf, H. Takwa
      Pages: 38 - 45
      Abstract: Amira A Gaballah, Alaa Eldin M Elgazzar, Hanan M Elshahat, Abdul Raheem I Yusuf, H. Takwa
      The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):38-45
      Introduction Mortality from lung abscesses continue to be substantial, even with surgical therapy, ranging from 15 to 20%. Image-guided percutaneous transthoracic drainage (PTD) improved lung abscess management and avoid complications of prolonged conservative treatment.Aim The aim of the study was to assess the outcome of nephrostomy catheter ultrasound (US)-guided PTD on lung abscess treatment in comparison to postural drainage in addition to medical treatment.Patients and methods A total of 30 patients with peripheral lung abscess were randomly assigned into two groups, the interventional group where US-guided percutaneous nephrostomy catheter was inserted in addition to medical treatment and the control group where postural drainage was done in addition to medical treatment. The following was done for all patients: thorough medical examination, neurological examination, routine laboratory investigations, radiological investigations (chest radiography, chest computed tomography, chest US), sputum culture and sensitivity.Results The study included 30 patients with lung abscess 18 men, and 12 women with a mean age of 44.6±9.5 years, (P>0.05). Regarding the outcome, success was higher among patients treated with catheter drainage 13/15 (86.6%) versus 8/15 (53.3%) patients in the control group (P<0.001), failure rate was less in the interventional group two (13.3%) versus seven (46.7%) patients in the control group (P<0.001); the treatment duration in the interventional group was significantly shorter 14.4±2.8 versus 26.9±3.8 days in the control group (P<0.001). Both groups were comparable regarding age, sex, abscess size, smoking, comorbidities and the distance between the abscess and chest wall. There were no reported major complications in the interventional group.Conclusion US-guided PTD using nephrostomy catheter for peripheral lung abscess is safe and effective; it can improve the outcome, shorten the duration and reduce the need for surgery in lung abscess treatment with less complications.
      Citation: The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):38-45
      PubDate: Wed,21 Mar 2018
      DOI: 10.4103/ejcdt.ejcdt_17_17
      Issue No: Vol. 67, No. 1 (2018)
       
  • Plasma asymmetric dimethylarginine in childhood asthma exacerbation

    • Authors: Adel S Bediwy, Samir M Hassan, Salwa A Ganna, Marwa R El-Najjar
      Pages: 46 - 49
      Abstract: Adel S Bediwy, Samir M Hassan, Salwa A Ganna, Marwa R El-Najjar
      The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):46-49
      Background Asymmetric dimethylarginine (ADMA) is a new marker of inflammation in different inflammatory disorders. Bronchial asthma as a chronic disease of inflammatory nature is related to an expanded levels of numerous markers of inflammation which are used to assess the degree of severity of childhood asthma and might be the object of new therapeutic alternatives aiming at enhancing the management of such diseases.Aim The aim of this study was to evaluate the plasma levels of ADMA in asthmatic children during asthma exacerbation and to assess the relationship between these levels and the degree of asthma control during the past 6 months.Patients and methods A total of 250 asthmatic children, aged 6–12 years, with acute exacerbation were evaluated during their visit to emergency room unit for serum ADMA (measured by high-performance liquid chromatography) and peak expiratory flow rate before receiving any treatment. They were 125 males and 125 females. Moreover, 100 participants were taken as controls.Results Plasma ADMA was significantly higher in asthmatic children compared with the control group. It was higher in asthmatic children who had poorer response to initial therapy at emergency room. Plasma ADMA showed significant negative correlation with peak expiratory flow rate and significant positive correlation with a number of asthma exacerbations during the past 6 monthsConclusion Plasma ADMA is elevated during exacerbation of childhood asthma. High levels above 2.83 μmol/l can predict poor response to initial therapy at emergency room and the need for hospitalization with sensitivity and specificity of 91.5 and 84.25%, respectively.
      Citation: The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):46-49
      PubDate: Wed,21 Mar 2018
      DOI: 10.4103/ejcdt.ejcdt_30_17
      Issue No: Vol. 67, No. 1 (2018)
       
  • Sonographic features of idiopathic pulmonary fibrosis

    • Authors: Osama F Mansour, Mohammed A Agha, Ahmed A Al-Asdody, Naglaa S Mehana, Rehab M Habib
      Pages: 50 - 55
      Abstract: Osama F Mansour, Mohammed A Agha, Ahmed A Al-Asdody, Naglaa S Mehana, Rehab M Habib
      The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):50-55
      Background Idiopathic pulmonary fibrosis (IPF) is a specific form of idiopathic interstitial pneumonia (IIP) that occurs primarily in the elderly and is confined to the lungs. With the use of transthoracic ultrasound (TUS), diffuse parenchymal lung disease should be considered if multiple comet-tail artifacts distributed over the whole surface of the lung together with a thickened and irregular, fragmented pleural line are visible.Objective The aim of this study was to evaluate lung ultrasound usefulness in the diagnosis of IPF.Patients and methods This study was carried out on 40 patients diagnosed as having IPF. All cases were subjected to a full assessment of history, clinical examination, laboratory investigations, arterial blood gases, pulmonary function test, plain chest radiography, high-resolution computed tomography, and TUS.Results Our results showed that B-lines in combination with thickened and irregular pleura are the TUS features of IPF. There was a statistically significant correlation among B-lines distance (mm), pleural line thickness (mm), pleural line irregularity, abolished lung sliding found by TUS, and severity of the disease.Conclusion TUS is a useful tool in the diagnosis and assessment of the severity of IPF and can be used as a complementary method beside high-resolution computed tomography. The distance between two adjacent lines in combination with thickened and irregular pleura is a good feature in the follow-up of disease progression.
      Citation: The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):50-55
      PubDate: Wed,21 Mar 2018
      DOI: 10.4103/ejcdt.ejcdt_38_17
      Issue No: Vol. 67, No. 1 (2018)
       
  • Heavy metals assessment in Egyptian smokers with lung cancer

    • Authors: Taha T Abdelgawad, Lucy A El-Maboud Suliman, Ahmed M Nabil Helaly, Shimaa M Motawei, Dalia A Abdelghany
      Pages: 56 - 61
      Abstract: Taha T Abdelgawad, Lucy A El-Maboud Suliman, Ahmed M Nabil Helaly, Shimaa M Motawei, Dalia A Abdelghany
      The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):56-61
      Background Smoking and heavy metals are major risk factors and have an important role in development of lung cancer.Purpose The purpose of this study was to investigate the relationship between development of lung cancer and the synergistic effect of smoking and heavy metals in Egyptian smokers.Patients and methods A total of 41 participants enrolled in this study and were subdivided into three groups: smokers with lung cancer (n=11), nonsmokers with lung cancer (n=15), and apparently healthy smokers (n=15). The diagnosis and types of lung cancer based on pathological examination of biopsies taken either by computed tomography-guided, ultrasound-guided, fiberoptic bronchoscopy (FOB), and blind or thoracoscopic pleural biopsy. Serum levels of five heavy metals (zinc, lead, nickel, manganese, chromium) were assayed using inductive plasma spectrometry.Results Squamous cell carcinoma represents the major type of lung cancer (72.7%) among group of smokers with lung cancer; however, adenocarcinoma either primary or metastatic represents the major type (93.4%) among the nonsmoker group, and all investigated heavy metals in this study (zinc, lead, nickel, manganese, chromium) express significantly higher mean value of their serum levels (P=0.005, 0.005, 0.006, <0.001, and 0.007, respectively) in case of squamous cell carcinoma compared with adenocarcinoma. There is no impact of the degree of severity of smoking on serum levels of all investigated heavy metals.Conclusion Squamous cell carcinoma has been strongly associated with higher serum levels of all investigated heavy metals. There is no association between degree of severity of smoking and serum levels of all investigated heavy metals.
      Citation: The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):56-61
      PubDate: Wed,21 Mar 2018
      DOI: 10.4103/ejcdt.ejcdt_10_17
      Issue No: Vol. 67, No. 1 (2018)
       
  • Assessment of the prevalence of pulmonary embolism in patients with severe
           pulmonary tuberculosis

    • Authors: Hany Shaarawy, Enas El-Sayed Mohamed
      Pages: 62 - 67
      Abstract: Hany Shaarawy, Enas El-Sayed Mohamed
      The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):62-67
      Background Tuberculosis (TB) is an infectious disease of public health concern. Many reports pointed to the association between TB and thromboembolic diseases. The aim of the present study is to assess the prevalence of pulmonary embolism in patients with severe pulmonary TB.Patients and methods The study was done on 50 (35 males and 15 females) patients with severe pulmonary TB, and all patients were proved to have pulmonary TB by sputum or BAL examination and culture. In all patients, causes of hypercoagulability state were excluded, and computed tomography (CT) pulmonary angiography was done to search for evidence of pulmonary embolism.Results Eight of 50 (16%) patients had evidence of pulmonary embolism, six (12%) patients had pulmonary embolism on the segmental and subsegmental level, and two (4%) patients had pulmonary embolism in the main pulmonary artery branches. The diagnosis of pulmonary embolism was done only by CT pulmonary angiography, as clinical and chest radiography signs were masked by those for pulmonary TB. Patients with evidence of pulmonary embolism were more hypoxic and had higher levels of D-dimer, but the difference was not statistically significant.Conclusion Pulmonary embolism should be searched for in patients with severe pulmonary TB. CT pulmonary angiography is the standard method for diagnosis and can be performed in those patients who are more hypoxemic. Prophylactic anticoagulation management can be justified in these patients. Larger studies are needed to define the risk factors in patients with severe pulmonary TB who are at an increased risk of developing pulmonary embolism.
      Citation: The Egyptian Journal of Chest Diseases and Tuberculosis 2018 67(1):62-67
      PubDate: Wed,21 Mar 2018
      DOI: 10.4103/ejcdt.ejcdt_12_17
      Issue No: Vol. 67, No. 1 (2018)
       
 
 
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