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Publisher: Medknow Publishers   (Total: 355 journals)

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Showing 1 - 200 of 355 Journals sorted alphabetically
Advanced Arab Academy of Audio-Vestibulogy J.     Open Access  
Advances in Human Biology     Open Access   (Followers: 1)
African J. for Infertility and Assisted Conception     Open Access  
African J. of Business Ethics     Open Access   (Followers: 6)
African J. of Medical and Health Sciences     Open Access   (Followers: 1)
African J. of Paediatric Surgery     Open Access   (Followers: 7, SJR: 0.269, h-index: 10)
African J. of Trauma     Open Access  
Ain-Shams J. of Anaesthesiology     Open Access   (Followers: 3)
Al-Azhar Assiut Medical J.     Open Access  
Al-Basar Intl. J. of Ophthalmology     Open Access   (Followers: 1)
Ancient Science of Life     Open Access   (Followers: 6)
Anesthesia : Essays and Researches     Open Access   (Followers: 7)
Annals of African Medicine     Open Access   (Followers: 1, SJR: 0.331, h-index: 15)
Annals of Bioanthropology     Open Access   (Followers: 3)
Annals of Cardiac Anaesthesia     Open Access   (Followers: 13, SJR: 0.408, h-index: 15)
Annals of Indian Academy of Neurology     Open Access   (Followers: 3, SJR: 0.308, h-index: 14)
Annals of Maxillofacial Surgery     Open Access   (Followers: 6)
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 7, SJR: 0.441, h-index: 10)
Annals of Saudi Medicine     Open Access   (SJR: 0.24, h-index: 29)
Annals of Thoracic Medicine     Open Access   (Followers: 4, SJR: 0.388, h-index: 19)
Annals of Tropical Medicine and Public Health     Open Access   (Followers: 15, SJR: 0.148, h-index: 5)
APOS Trends in Orthodontics     Open Access   (Followers: 1)
Arab J. of Interventional Radiology     Open Access  
Archives of Intl. Surgery     Open Access   (Followers: 9)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Archives of Pharmacy Practice     Open Access   (Followers: 5)
Asia Pacific J. of Clinical Trials : Nervous System Diseases     Open Access  
Asia-Pacific J. of Oncology Nursing     Open Access   (Followers: 3)
Asian J. of Andrology     Open Access   (Followers: 1, SJR: 0.879, h-index: 49)
Asian J. of Neurosurgery     Open Access   (Followers: 2)
Asian J. of Oncology     Open Access   (Followers: 1)
Asian J. of Transfusion Science     Open Access   (Followers: 2, SJR: 0.362, h-index: 10)
Astrocyte     Open Access  
Avicenna J. of Medicine     Open Access   (Followers: 1)
AYU : An international quarterly journal of research in Ayurveda     Open Access   (Followers: 6)
Benha Medical J.     Open Access  
BLDE University J. of Health Sciences     Open Access  
Brain Circulation     Open Access  
Bulletin of Faculty of Physical Therapy     Open Access   (Followers: 1)
Cancer Translational Medicine     Open Access   (Followers: 1)
CHRISMED J. of Health and Research     Open Access  
Clinical Dermatology Review     Open Access   (Followers: 1)
Clinical Trials in Degenerative Diseases     Open Access  
Clinical Trials in Orthopedic Disorders     Open Access   (Followers: 1)
Community Acquired Infection     Open Access  
Conservation and Society     Open Access   (Followers: 12, SJR: 0.82, h-index: 12)
Contemporary Clinical Dentistry     Open Access   (Followers: 4)
Current Medical Issues     Open Access   (Followers: 1)
CytoJ.     Open Access   (Followers: 2, SJR: 0.339, h-index: 19)
Delta J. of Ophthalmology     Open Access  
Dental Hypotheses     Open Access   (Followers: 3, SJR: 0.131, h-index: 4)
Dental Research J.     Open Access   (Followers: 9)
Dentistry and Medical Research     Open Access  
Digital Medicine     Open Access  
Drug Development and Therapeutics     Open Access  
Education for Health     Open Access   (Followers: 5, SJR: 0.205, h-index: 22)
Egyptian J. of Bronchology     Open Access  
Egyptian J. of Cardiothoracic Anesthesia     Open Access  
Egyptian J. of Cataract and Refractive Surgery     Open Access   (Followers: 1)
Egyptian J. of Dermatology and Venerology     Open Access   (Followers: 1)
Egyptian J. of Haematology     Open Access  
Egyptian J. of Internal Medicine     Open Access   (Followers: 1)
Egyptian J. of Neurology, Psychiatry and Neurosurgery     Open Access   (Followers: 1, SJR: 0.121, h-index: 3)
Egyptian J. of Obesity, Diabetes and Endocrinology     Open Access  
Egyptian J. of Otolaryngology     Open Access   (Followers: 1)
Egyptian J. of Psychiatry     Open Access   (Followers: 2)
Egyptian J. of Surgery     Open Access   (Followers: 1)
Egyptian Orthopaedic J.     Open Access  
Egyptian Pharmaceutical J.     Open Access  
Egyptian Retina J.     Open Access  
Egyptian Rheumatology and Rehabilitation     Open Access  
Endodontology     Open Access  
Endoscopic Ultrasound     Open Access   (SJR: 0.473, h-index: 8)
Environmental Disease     Open Access  
European J. of Dentistry     Open Access   (Followers: 2, SJR: 0.496, h-index: 11)
European J. of General Dentistry     Open Access   (Followers: 1)
European J. of Prosthodontics     Open Access   (Followers: 2)
European J. of Psychology and Educational Studies     Open Access   (Followers: 7)
Fertility Science and Research     Open Access  
Formosan J. of Surgery     Open Access   (SJR: 0.107, h-index: 5)
Genome Integrity     Open Access   (Followers: 4, SJR: 1.227, h-index: 12)
Global J. of Transfusion Medicine     Open Access   (Followers: 1)
Heart India     Open Access   (Followers: 1)
Heart Views     Open Access   (Followers: 2)
Hepatitis B Annual     Open Access   (Followers: 3)
IJS Short Reports     Open Access  
Indian Anaesthetists Forum     Open Access  
Indian Dermatology Online J.     Open Access   (Followers: 3)
Indian J. of Allergy, Asthma and Immunology     Open Access   (Followers: 1)
Indian J. of Anaesthesia     Open Access   (Followers: 8, SJR: 0.302, h-index: 13)
Indian J. of Burns     Open Access   (Followers: 1)
Indian J. of Cancer     Open Access   (SJR: 0.318, h-index: 26)
Indian J. of Cerebral Palsy     Open Access   (Followers: 1)
Indian J. of Community Medicine     Open Access   (Followers: 2, SJR: 0.618, h-index: 16)
Indian J. of Critical Care Medicine     Open Access   (Followers: 2, SJR: 0.307, h-index: 16)
Indian J. of Dental Research     Open Access   (Followers: 4, SJR: 0.243, h-index: 24)
Indian J. of Dental Sciences     Open Access  
Indian J. of Dentistry     Open Access   (Followers: 1)
Indian J. of Dermatology     Open Access   (Followers: 2, SJR: 0.448, h-index: 16)
Indian J. of Dermatology, Venereology and Leprology     Open Access   (Followers: 3, SJR: 0.563, h-index: 29)
Indian J. of Dermatopathology and Diagnostic Dermatology     Open Access  
Indian J. of Drugs in Dermatology     Open Access   (Followers: 1)
Indian J. of Endocrinology and Metabolism     Open Access   (Followers: 4)
Indian J. of Health Sciences     Open Access   (Followers: 2)
Indian J. of Medical and Paediatric Oncology     Open Access   (SJR: 0.292, h-index: 9)
Indian J. of Medical Microbiology     Open Access   (Followers: 1, SJR: 0.53, h-index: 34)
Indian J. of Medical Research     Open Access   (Followers: 4, SJR: 0.716, h-index: 60)
Indian J. of Medical Sciences     Open Access   (Followers: 2, SJR: 0.207, h-index: 31)
Indian J. of Multidisciplinary Dentistry     Open Access   (Followers: 1)
Indian J. of Nephrology     Open Access   (Followers: 1, SJR: 0.233, h-index: 12)
Indian J. of Nuclear Medicine     Open Access   (Followers: 2, SJR: 0.213, h-index: 5)
Indian J. of Occupational and Environmental Medicine     Open Access   (Followers: 4, SJR: 0.203, h-index: 13)
Indian J. of Ophthalmology     Open Access   (Followers: 5, SJR: 0.536, h-index: 34)
Indian J. of Oral Health and Research     Open Access  
Indian J. of Oral Sciences     Open Access   (Followers: 1)
Indian J. of Orthopaedics     Open Access   (Followers: 9, SJR: 0.393, h-index: 15)
Indian J. of Otology     Open Access   (Followers: 1, SJR: 0.218, h-index: 5)
Indian J. of Paediatric Dermatology     Open Access   (Followers: 2)
Indian J. of Pain     Open Access   (Followers: 1)
Indian J. of Palliative Care     Open Access   (Followers: 5, SJR: 0.35, h-index: 12)
Indian J. of Pathology and Microbiology     Open Access   (Followers: 1, SJR: 0.285, h-index: 22)
Indian J. of Pharmacology     Open Access   (SJR: 0.347, h-index: 44)
Indian J. of Plastic Surgery     Open Access   (Followers: 12, SJR: 0.303, h-index: 13)
Indian J. of Psychiatry     Open Access   (Followers: 3, SJR: 0.496, h-index: 15)
Indian J. of Psychological Medicine     Open Access   (Followers: 1, SJR: 0.344, h-index: 9)
Indian J. of Public Health     Open Access   (Followers: 1, SJR: 0.444, h-index: 17)
Indian J. of Radiology and Imaging     Open Access   (Followers: 4, SJR: 0.253, h-index: 14)
Indian J. of Research in Homoeopathy     Open Access  
Indian J. of Rheumatology     Open Access   (SJR: 0.169, h-index: 7)
Indian J. of Sexually Transmitted Diseases and AIDS     Open Access   (Followers: 2, SJR: 0.313, h-index: 9)
Indian J. of Social Psychiatry     Open Access   (Followers: 2)
Indian J. of Urology     Open Access   (Followers: 3, SJR: 0.366, h-index: 16)
Indian J. of Vascular and Endovascular Surgery     Open Access   (Followers: 2)
Industrial Psychiatry J.     Open Access   (Followers: 2)
Intl. J. of Academic Medicine     Open Access  
Intl. J. of Advanced Medical and Health Research     Open Access  
Intl. J. of Applied and Basic Medical Research     Open Access  
Intl. J. of Clinical and Experimental Physiology     Open Access   (Followers: 1)
Intl. J. of Critical Illness and Injury Science     Open Access   (Followers: 1)
Intl. J. of Educational and Psychological Researches     Open Access   (Followers: 3)
Intl. J. of Environmental Health Engineering     Open Access   (Followers: 1)
Intl. J. of Forensic Odontology     Open Access   (Followers: 1)
Intl. J. of Green Pharmacy     Open Access   (Followers: 4, SJR: 0.229, h-index: 13)
Intl. J. of Health & Allied Sciences     Open Access   (Followers: 3)
Intl. J. of Health System and Disaster Management     Open Access   (Followers: 2)
Intl. J. of Heart Rhythm     Open Access  
Intl. J. of Medicine and Public Health     Open Access   (Followers: 7)
Intl. J. of Mycobacteriology     Open Access   (SJR: 0.239, h-index: 4)
Intl. J. of Noncommunicable Diseases     Open Access  
Intl. J. of Nutrition, Pharmacology, Neurological Diseases     Open Access   (Followers: 4)
Intl. J. of Oral Health Sciences     Open Access   (Followers: 1)
Intl. J. of Orthodontic Rehabilitation     Open Access  
Intl. J. of Pedodontic Rehabilitation     Open Access  
Intl. J. of Pharmaceutical Investigation     Open Access   (Followers: 1)
Intl. J. of Preventive Medicine     Open Access   (Followers: 1, SJR: 0.523, h-index: 15)
Intl. J. of Shoulder Surgery     Open Access   (Followers: 7, SJR: 0.611, h-index: 9)
Intl. J. of Trichology     Open Access   (SJR: 0.37, h-index: 10)
Intl. J. of Yoga     Open Access   (Followers: 15)
Intl. J. of Yoga : Philosophy, Psychology and Parapsychology     Open Access   (Followers: 6)
Iranian J. of Nursing and Midwifery Research     Open Access   (Followers: 2)
Iraqi J. of Hematology     Open Access  
J. of Academy of Medical Sciences     Open Access  
J. of Advanced Pharmaceutical Technology & Research     Open Access   (Followers: 4, SJR: 0.427, h-index: 15)
J. of Anaesthesiology Clinical Pharmacology     Open Access   (Followers: 8, SJR: 0.416, h-index: 14)
J. of Applied Hematology     Open Access  
J. of Association of Chest Physicians     Open Access   (Followers: 2)
J. of Basic and Clinical Reproductive Sciences     Open Access   (Followers: 1)
J. of Cancer Research and Therapeutics     Open Access   (Followers: 4, SJR: 0.359, h-index: 21)
J. of Carcinogenesis     Open Access   (Followers: 1, SJR: 1.152, h-index: 26)
J. of Cardiothoracic Trauma     Open Access  
J. of Cardiovascular Disease Research     Open Access   (Followers: 3, SJR: 0.351, h-index: 13)
J. of Cardiovascular Echography     Open Access   (SJR: 0.134, h-index: 2)
J. of Cleft Lip Palate and Craniofacial Anomalies     Open Access   (Followers: 2)
J. of Clinical and Preventive Cardiology     Open Access   (Followers: 1)
J. of Clinical Imaging Science     Open Access   (Followers: 1, SJR: 0.277, h-index: 8)
J. of Clinical Neonatology     Open Access   (Followers: 1)
J. of Clinical Ophthalmology and Research     Open Access   (Followers: 2)
J. of Clinical Sciences     Open Access  
J. of Conservative Dentistry     Open Access   (Followers: 4, SJR: 0.532, h-index: 10)
J. of Craniovertebral Junction and Spine     Open Access   (Followers: 4, SJR: 0.199, h-index: 9)
J. of Current Medical Research and Practice     Open Access  
J. of Current Research in Scientific Medicine     Open Access  
J. of Cutaneous and Aesthetic Surgery     Open Access   (Followers: 1)
J. of Cytology     Open Access   (Followers: 1, SJR: 0.274, h-index: 9)
J. of Dental and Allied Sciences     Open Access   (Followers: 1)
J. of Dental Implants     Open Access   (Followers: 7)
J. of Dental Lasers     Open Access   (Followers: 2)
J. of Dental Research and Review     Open Access   (Followers: 1)
J. of Digestive Endoscopy     Open Access   (Followers: 3)
J. of Dr. NTR University of Health Sciences     Open Access  
J. of Earth, Environment and Health Sciences     Open Access   (Followers: 1)
J. of Education and Ethics in Dentistry     Open Access   (Followers: 5)
J. of Education and Health Promotion     Open Access   (Followers: 5)
J. of Emergencies, Trauma and Shock     Open Access   (Followers: 9, SJR: 0.353, h-index: 14)
J. of Engineering and Technology     Open Access   (Followers: 6)
J. of Experimental and Clinical Anatomy     Open Access   (Followers: 2)
J. of Family and Community Medicine     Open Access   (Followers: 2)
J. of Family Medicine and Primary Care     Open Access   (Followers: 10)

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Journal Cover Journal of Clinical Neonatology
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  This is an Open Access Journal Open Access journal
   ISSN (Print) 2249-4847
   Published by Medknow Publishers Homepage  [355 journals]
  • Noninvasive ventilation: Systematic approach and new perspectives for
           preterm infants

    • Authors: Gianfranco Maffei, Sara Gorgoglione, Giovanni Vento
      Pages: 135 - 143
      Abstract: Gianfranco Maffei, Sara Gorgoglione, Giovanni Vento
      Journal of Clinical Neonatology 2017 6(3):135-143
      Noninvasive ventilation (NIV) refers to the delivery of ventilatory support through nasal prongs/mask. NIV, associated with nasal continuous positive airway pressure, representing the main method to improve the functional residual capacity in the newborn (at term or preterm) avoiding invasive actions such as tracheal intubation.
      Citation: Journal of Clinical Neonatology 2017 6(3):135-143
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_121_16
      Issue No: Vol. 6, No. 3 (2017)
       
  • Role of hematological scoring system in diagnosis of neonatal sepsis

    • Authors: Mihir J Bhalodia, Surekha B Hippargi, MM Patil
      Pages: 144 - 147
      Abstract: Mihir J Bhalodia, Surekha B Hippargi, MM Patil
      Journal of Clinical Neonatology 2017 6(3):144-147
      Background: Neonatal sepsis is one of the major causes of morbidity and mortality in the newborn, more so in the developing countries. The incidence of neonatal sepsis has been reported to be 30/1000 live births according to National Neonatal Perinatal Database. Objectives: To analyze the diagnostic utility of hematological scoring system (HSS) and its correlation with C-reactive protein and blood culture in neonatal sepsis. Materials and Methods: This prospective study included 150 neonates admitted to Neonatal Intensive Care Unit with clinical suspicion of neonatal sepsis from November 2012 to April 2014, considering the inclusion and exclusion criteria. Results: HSS had the highest sensitivity (93.7%) and identified >90% of neonates with clinical suspicion of sepsis. Furthermore, total leukocyte count showed high specificity but least sensitivity, immature to total ratio and immature to mature ratio showed high specificity and high sensitivity, and platelet count showed high negative predictive value and least positive predictive value. Conclusion: HSS is a simple, easy, cheap, and rapid adjunct for the diagnosis of clinically suspected cases of neonatal sepsis.
      Citation: Journal of Clinical Neonatology 2017 6(3):144-147
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_158_15
      Issue No: Vol. 6, No. 3 (2017)
       
  • Effect of phototherapy on the diagnostic accuracy of transcutaneous
           bilirubin in preterm infants

    • Authors: Gaurav Nagar, Manoj Kumar
      Pages: 148 - 153
      Abstract: Gaurav Nagar, Manoj Kumar
      Journal of Clinical Neonatology 2017 6(3):148-153
      Objectives: The objective of this study was to evaluate the diagnostic accuracy of JM-103 transcutaneous bilirubinmeter (TcB) in preterm infants during phototherapy (PT) and in post-PT phase. Methods: This was a prospective cohort study. Infants born between 28 and 35 weeks of gestation and at <28 days of postnatal age were eligible if they required bilirubin estimation during the NICU stay. TcB was measured within 30 minutes of the blood sampling for serum bilirubin, at forehead and sternum. Mean difference (±standard deviation [SD]) and 95% limits of agreement between TcB and total serum bilirubin (TSB) were calculated by analyzing Bland–Altman difference plots. We also calculated correlation coefficients. Results: Ninety infants were enrolled. During PT, the difference plots revealed a wide TcB-TSB disagreement; 95% agreement limits of data indicated that TcB could underestimate bilirubin levels by up to 132 μmol/L at forehead and 157 μmol/L at sternum (Mean difference ± SD of −52.4 mmol/L ± 40.7 at forehead and −69.2 mmol/L ± 42.5 at sternum) and a poor TcB-TSB correlation (r = 0.72 at forehead and 0.51 at sternum). In post-PT phase, correlation coefficients improved significantly and were equivalent to the estimates before the onset of PT (r = 0.88 at forehead and 0.87 at sternum). The analyses of difference plots revealed that TcB could underestimate bilirubin levels up to 88 μmol/L in this phase (Mean difference ± SD of −28.8 mmol/L ± 30.5 at forehead and −19.6 mmol/L ± 34.7 at sternum). Conclusions: JM-103 device is unreliable for estimating bilirubin during PT. However, TcB-TSB agreement improved substantially in the post-PT phase such that use of the TcB device could lead to a reduction in blood sampling during this phase.
      Citation: Journal of Clinical Neonatology 2017 6(3):148-153
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_94_16
      Issue No: Vol. 6, No. 3 (2017)
       
  • Correlation of transcutaneous bilirubin and serum bilirubin concentration
           in term and late preterm newborns

    • Authors: Sushil Gunaseelan, Sahana Devadas, Nandita Pai
      Pages: 154 - 158
      Abstract: Sushil Gunaseelan, Sahana Devadas, Nandita Pai
      Journal of Clinical Neonatology 2017 6(3):154-158
      Objective: Neonatal jaundice is a common condition requiring evaluation and treatment for most newborns. However, kernicterus is just a “tip of the iceberg” of bilirubin-induced neurologic dysfunction. The objective of this study is to evaluate the use of a transcutaneous bilirubinometer for the detection of hyperbilirubinemia in newborns. Design and Setting: In this prospective study, we measured Transcutaneous bilirubin (TcB) concentration in clinically icteric term and late preterm babies. Total serum bilirubin (TSB) was measured if the initial TcB level was higher than the 50th centile in Bhutani's nomogram. Paired TcB and TSB results were correlated, and the mean difference was calculated. Patients: Neonates of gestational age more than 35 weeks and weighing more than 2 kg were included in this study. TcB recordings were taken in neonates who appeared clinically icteric. Results: Four hundred paired TcB and TSB measurements were taken. TcB was significantly correlating with TSB (P < 0.001) in both low-risk and medium-risk thresholds for phototherapy. TcB had a sensitivity and negative predictive value of 100% each, a specificity of 56%, and a positive predictive value of 23%. For high-risk cases, using the 75th centile as cutoff, the sensitivity and negative predictive value were reduced to 88% and 97.0%, respectively. Conclusion: TcB correlates closely with TSB concentration in neonates born after 35 weeks gestation. The rate of rise in TcB may help in identification of neonates at risk and minimizing invasive blood investigations.
      Citation: Journal of Clinical Neonatology 2017 6(3):154-158
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_109_16
      Issue No: Vol. 6, No. 3 (2017)
       
  • Association between sepsis calculator and infection parameters for
           newborns with suspected early onset sepsis

    • Authors: Niek B Achten, Rens Zonneveld, Ellen Tromp, Frans B Pl&#246;tz
      Pages: 159 - 162
      Abstract: Niek B Achten, Rens Zonneveld, Ellen Tromp, Frans B Plötz
      Journal of Clinical Neonatology 2017 6(3):159-162
      Context: Early-onset sepsis remains an important clinical problem with significant antibiotic overtreatment as a result of poor specificity of clinical and infection parameters. Quantitative risk stratification models such as the early-onset neonatal sepsis (EOS) calculator are promising, but it is unclear how these models relate to infection parameters in the first 72 h of life. Aim: The aim of this study is to evaluate the hypothesis that higher EOS calculator results are associated with (serial) laboratory infection parameters, in particular an increase in C-reactive protein (CRP) within 24–48 h and low leukocyte counts. Subjects and Methods: EOS risk estimates were determined for infants born ≥34 weeks of gestation who were started on antibiotic treatment for suspected EOS within 72 h after birth. EOS risk estimates were retrospectively compared to (changes in) available laboratory infection parameters, including CRP, leukocyte, and thrombocyte count. Statistical Analysis Used: Spearman's rho rank correlations coefficient was used when testing for correlations between continuous parameters. Kruskal–Wallis and Mann–Whitney U-tests were applied to differences between stratified risk groups. Results: EOS risk was not correlated with changes in infection parameters. We found negative correlations between both EOS risk and CRP level and leukocyte count within 6 h of the start of antibiotics, as well as CRP level between 6 and 24 h after start of treatment. Conclusions: In contrast to our hypothesis, high EOS risk at birth was consistently correlated with lower CRP and leukocyte counts within 24 h after the start of antibiotics, but not with infection parameters after 24 h. Further interpretation of infection parameters during sepsis calculator use needs to be elucidated.
      Citation: Journal of Clinical Neonatology 2017 6(3):159-162
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_110_16
      Issue No: Vol. 6, No. 3 (2017)
       
  • Hypoglycemic relapse in term infants treated with glucose infusion

    • Authors: Julie Sternberg, Riccardo E Pfister, Oliver Karam
      Pages: 163 - 167
      Abstract: Julie Sternberg, Riccardo E Pfister, Oliver Karam
      Journal of Clinical Neonatology 2017 6(3):163-167
      Background: Hypoglycemia, being a common, potentially serious problem in neonatology, is screened in at-risk newborzns. However, there is little evidence regarding the screening of hypoglycemic relapse after treatment by glucose infusion. Objectives: We aimed to determine whether measuring blood glucose levels 3, 6, and 9 h after weaning from glucose infusion is appropriate to detect hypoglycemic relapse. Methods: This is a single-center retrospective study (2005–2014) measuring the proportion of infants who experienced hypoglycemic relapse (glucose level <2.5 mmol/L) after withdrawal of glucose infusion as well as the “time to relapse” in a population of 129 consecutive patients treated with glucose infusion for severe or prolonged neonatal hypoglycemia. Results: No newborn (0%, 95% confidence interval [CI]: 0%–2.9%) had hypoglycemic relapse within the first 3 h after weaning from glucose infusion. Five infants (3.9%, 95% CI: 1.7%–8.8%) and three infants (2.3%, 95% CI: 0.8%–6.6%) had hypoglycemic relapse, respectively, 6 and 9 h after weaning. All relapses were of mild severity (blood glucose level: 2.0–2.5 mmol/L). Lower birth weight (BW) (P = 0.008) and small for gestational age (SGA) (P = 0.003) were associated with the increased risk of hypoglycemic relapse. Conclusions: In a population of term newborns presenting with hypoglycemia requiring glucose infusion, only a small proportion presented with mild hypoglycemia relapse after weaning from infusion, lower BW and SGA were the main risk factors. Future research should assess whether it is sufficient to control only at-risk infants for relapse after a progressive weaning from infusion.
      Citation: Journal of Clinical Neonatology 2017 6(3):163-167
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_10_17
      Issue No: Vol. 6, No. 3 (2017)
       
  • Exchange blood transfusion: Its metabolic and cardiorespiratory effect in
           newborns

    • Authors: Ibrahim Aliyu, Abdulsalam Mohammed, Zubaida Ladan Farouk, Zainab Fumilayo Ibrahim
      Pages: 168 - 172
      Abstract: Ibrahim Aliyu, Abdulsalam Mohammed, Zubaida Ladan Farouk, Zainab Fumilayo Ibrahim
      Journal of Clinical Neonatology 2017 6(3):168-172
      Introduction: Neonatal jaundice constitutes 20% of admissions, and kernicterus is seen in 8% of cases while mortality rate of 6% has recorded across centers in Nigeria. There are various modalities for the management of neonatal hyperbilirubinemia including exchange blood transfusion (EBT). This study seeks to determine blood glucose and vital signs changes associated with EBT. Materials and Methods: The study was cross-sectional; carried out at the Special Care Baby Unit of Aminu Kano Teaching Hospital, Kano. Neonates requiring EBT from unconjugated hyperbilirubinemia were recruited. Results: There were 20 neonates enrolled, 18 (90%) males and 2 (10%) females with male to female ratio of 9:1. The turnaround time ranged from 3 to 31 h with mean value of 10.4 ± 7.9 h; however, most of the neonates (60%) had EBT more than 5 h after presentation. The mean temperature before EBT was 36.9°C ± 0.4°C; while after EBT, it was 36.2°C ± 0.5°C, and no case of hypothermia was documented. The mean respiratory rate before EBT was 46.3 ± 5.2 cycles/min; while after EBT, it was 51.9 ± 9.1 cycles/min; with no record of apnea. Mean heart rate was 143.8 ± 7.1 beats/min before the procedure and was 145 ± 15 beats/min after EBT. The mean serum glucose concentration before EBT was 4.5 ± 2.7 mmol/L, while it was 4.9 ± 2.2 mmol/L after EBT. Conclusion: Our study documented higher respiratory and heart rates post procedure with no record of apnea; furthermore, the serum sugar remained normal post-EBT.
      Citation: Journal of Clinical Neonatology 2017 6(3):168-172
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_18_17
      Issue No: Vol. 6, No. 3 (2017)
       
  • Does hypoxemia occur before, during or after lumbar puncture procedure in
           ill newborns? Our experience in a tertiary health center

    • Authors: Chika O Duru, Ovuirororie Ebi Ederiane, Daukoru Allen-Ameri, Zainab Fumilayo Ibrahim, Kemebradikumo Pondei, Ibrahim Aliyu
      Pages: 173 - 178
      Abstract: Chika O Duru, Ovuirororie Ebi Ederiane, Daukoru Allen-Ameri, Zainab Fumilayo Ibrahim, Kemebradikumo Pondei, Ibrahim Aliyu
      Journal of Clinical Neonatology 2017 6(3):173-178
      Introduction: Lumbar puncture (LP) remains an important diagnostic investigation in the septic workup of ill newborns. There is rising concern in its use in all critically ill newborns due to its invasive nature as well as the risk of complications; however, examining the cerebrospinal fluid remains the cornerstone to establishing the diagnosis of meningitis. Methodology: The study design was cross-sectional, and a convenient sampling method was adopted. Thirty-one ill newborns admitted consecutively into the special care baby unit of our institution with diagnosis of sepsis and/or meningitis were recruited from July 2015 to December 2015. Results: There were 11 (35.5%) males and 20 (64.5%) females with male to female of 1:1.8. The mean oxygen saturation (SpO2) 5 min before positioning for LP was normal at 95.1% ± 4.6% however this reduced to 90.9% ± 4.1%, but this progressively improved with the mean value 5 min after repositioning to supine been normal at 96.2% ± 3.0%. The mean SpO2was generally lower in those with LP lasting more than 5 min but it was lowest during the phase of needle insertion (89.8% ± 4.3%). Comparing the SpO2during various phases of LP showed that the extent of desaturation was greatest during the stage of spinal needle insertion, and this was statistically significant with Student's t-test (paired) value = 4.649, df = 30 and P = 0.001. Conclusion: LP in the newborn may be associated with significant hypoxia especially in those with prolonged duration of the procedure; therefore routine oxygen monitoring using the pulse oximeter is advised.
      Citation: Journal of Clinical Neonatology 2017 6(3):173-178
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_23_17
      Issue No: Vol. 6, No. 3 (2017)
       
  • Novel ubiquitin protein ligase E3 component N-Recognin 1 gene mutation in
           johanson–blizzard syndrome: Development of hypothyroidism during
           infancy

    • Authors: Muhittin Celik, Ali Bulbul, &#214;zg&#252;r Kirbiyik, Belgin Kesim, Sinan Uslu, Maja Sukalo, Martin Zenker
      Pages: 179 - 181
      Abstract: Muhittin Celik, Ali Bulbul, Özgür Kirbiyik, Belgin Kesim, Sinan Uslu, Maja Sukalo, Martin Zenker
      Journal of Clinical Neonatology 2017 6(3):179-181
      Johanson–Blizzard syndrome (JBS) is a rare autosomal recessive disorder, characterized by exocrine pancreatic deficiency and a wide range of other abnormalities. Here, we present an infant with failure to thrive, exocrine pancreatic deficiency, developmental delay, cutis aplasia on the scalp, aplasia of alae nasi, hypospadias, and hypothyroidism. Molecular studies revealed a novel homozygous nonsense mutation in exon exon 22 of the ubiquitin protein ligase E3 component N-recognin 1 gene, which confirmed the diagnosis of JBS. In conclusion, it was reported that mutations were mostly family-specific and the same mutation was rarely present in another family. Autosomal recessive diseases are more common in Turkey than in other European countries due to the high frequency of consanguineous marriage. Investigations revealed deafness and congenital hypothyroidism.
      Citation: Journal of Clinical Neonatology 2017 6(3):179-181
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_204_15
      Issue No: Vol. 6, No. 3 (2017)
       
  • Testicular torsion &#8211; an important consideration in neonatal
           scrotal swelling

    • Authors: Stine Hoffmann, Charlotte Kruse, Bo L Chawes
      Pages: 182 - 184
      Abstract: Stine Hoffmann, Charlotte Kruse, Bo L Chawes
      Journal of Clinical Neonatology 2017 6(3):182-184
      Scrotal swelling in a neonate is rarely caused by testicular torsion, but it is an important differential diagnosis as acute treatment can prevent loss of fertility. The clinical findings differ, depending on whether the torsion has occurred in utero (prenatal) or after birth (postnatal). Postnatal testicular torsion presents with pain, redness, and swelling of the affected testis and requires acute surgical intervention to restore the blood flow and prevent ischemic necrosis. Contrary, prenatal testicular torsion will present with a hard, discolored untender mass that has already atrophied. It is important to quickly distinguish between prenatal versus postnatal cases to enable timely surgery of postnatal torsion, whereas the treatment of prenatal torsion is less urgent. A thorough clinical examination and ultrasonography with Doppler to detect blood flow or the lack of flow are the cornerstones in establishing an early diagnosis.
      Citation: Journal of Clinical Neonatology 2017 6(3):182-184
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_57_16
      Issue No: Vol. 6, No. 3 (2017)
       
  • Neonatal cellulitis-adenitis syndrome caused by Klebsiella oxytoca

    • Authors: Evelien Kuiper-Prins, Sylvia Brigitte Debast, Esther Jean d&#39; Haens, Marieke Anne Catharine Hemels
      Pages: 185 - 186
      Abstract: Evelien Kuiper-Prins, Sylvia Brigitte Debast, Esther Jean d' Haens, Marieke Anne Catharine Hemels
      Journal of Clinical Neonatology 2017 6(3):185-186
      Cellulitis-adenitis syndrome is rarely diagnosed in the neonatal period and generally associated with group B streptococci infection. We present the first report of cellulitis-adenitis syndrome of the axilla due to Klebsiella oxytoca in a premature infant. Therefore, empiric antibiotic treatment for cellulitis-adenitis syndrome in the neonatal period should include antibiotics that act against both Gram-positive and Gram-negative bacteria.
      Citation: Journal of Clinical Neonatology 2017 6(3):185-186
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_116_16
      Issue No: Vol. 6, No. 3 (2017)
       
  • Iatrogenic lung collapse in a neonate after recurrent endotracheal
           intubations and tracheal suctioning

    • Authors: Mohammad Alsalem, Ahmad I Alomari, Eid Kakish, Samah Awad
      Pages: 187 - 189
      Abstract: Mohammad Alsalem, Ahmad I Alomari, Eid Kakish, Samah Awad
      Journal of Clinical Neonatology 2017 6(3):187-189
      Iatrogenic lung collapse due to complete main stem bronchus obstruction caused by recurrent intubations and repetitive tracheal toileting has been rarely reported in literature. The early diagnosis and proper management are imperative to avoid mortality. A 1-month-old male child, weighing 3 kg, developed a complete right main bronchus obstruction caused by granulation tissue, after multiple intubations and prolonged pediatric Intensive Care Unit ICU care, leading to a complete right lung collapse. Removal of the granulation tissue was complete and successful using rigid bronchoscopy and forceps. Careful atraumatic intubation should be attempted in all patients with extra care in the neonatal age group. An experienced doctor or experienced attentive pediatric ICU nurses should handle the bronchial suctioning of neonates to avoid trauma to the tracheal structures. A bronchial obstruction that may result in lung collapse should be suspected after traumatic or prolonged intubation with frequent airway suctioning, where the early diagnosis and proper management are imperative to avoid mortality.
      Citation: Journal of Clinical Neonatology 2017 6(3):187-189
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_117_16
      Issue No: Vol. 6, No. 3 (2017)
       
  • Gastroschisis with single, large intestinal perforations in a preterm
           neonate: A very rare case

    • Authors: Aditya Pratap Singh, Vinay Mathur, Ramesh Tanger, Arun Kumar Gupta
      Pages: 190 - 191
      Abstract: Aditya Pratap Singh, Vinay Mathur, Ramesh Tanger, Arun Kumar Gupta
      Journal of Clinical Neonatology 2017 6(3):190-191
      Several cases of bowel perforation in patients with intestinal atresia have been reported in the literature. Gastroschisis is known to be associated with multiple intestinal perforations. We report the case of a preterm neonate with gastroschisis who presented with single large perforation in the ileum with no associated intestinal atresia.
      Citation: Journal of Clinical Neonatology 2017 6(3):190-191
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_118_16
      Issue No: Vol. 6, No. 3 (2017)
       
  • Recurrent late-onset group B streptococcus sepsis in a neonate from breast
           milk

    • Authors: Soumya R Thomas, Tasnim Dawoud, Iman Doss, Zakariya Al-Salam
      Pages: 192 - 194
      Abstract: Soumya R Thomas, Tasnim Dawoud, Iman Doss, Zakariya Al-Salam
      Journal of Clinical Neonatology 2017 6(3):192-194
      Group B streptococcus (GBS) or Streptococcus agalactiae is a cause of considerable neonatal morbidity and mortality. Intrapartum antibiotic prophylaxis for mothers colonized with GBS has markedly reduced the rates of early-onset neonatal GBS bacteremia. Recurrent late-onset GBS bacteremia is a rare occurrence. Mucosal colonization and breast milk contamination have been implicated as causes of the recurrence. We report a case of recurrent late-onset neonatal GBS bacteremia from the United Arab Emirates, in a term baby whose mother was GBS negative on antenatal screens, with breast milk culture positivity for GBS. To our knowledge, this is the first report from the Middle East region.
      Citation: Journal of Clinical Neonatology 2017 6(3):192-194
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_6_17
      Issue No: Vol. 6, No. 3 (2017)
       
  • Bradycardia in a 10 hours neonate secondary to severe maternal
           hypovitaminosis D

    • Authors: Neeraj Kumar, Neeraj Aggarwal, Reena Khantwal Joshi, Raja Joshi
      Pages: 195 - 197
      Abstract: Neeraj Kumar, Neeraj Aggarwal, Reena Khantwal Joshi, Raja Joshi
      Journal of Clinical Neonatology 2017 6(3):195-197
      Late-onset hypocalcemia is a commonly reported metabolic abnormality in neonates secondary to maternal hypovitaminosis D. Symptomatic early-onset hypocalcemia without risk factors in a neonate is uncommon. Severe maternal Vitamin D deficiency has only occasionally been reported in a case series from the Middle-East to cause early-onset hypocalcemia (<3 days) in neonates. We report an unusual case of early-onset hypocalcemia in a 10 hours neonate manifesting as bradycardia with prolonged QT interval secondary to maternal Vitamin D deficiency.
      Citation: Journal of Clinical Neonatology 2017 6(3):195-197
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_13_17
      Issue No: Vol. 6, No. 3 (2017)
       
  • Arteriovenous fistula in a neonate utility of the bedside echocardiography

    • Authors: Iyer Harohalli Venkatesh, Vijayalakshmi Sathi, Pragya Deo Sharma, Abhishek Paul
      Pages: 198 - 199
      Abstract: Iyer Harohalli Venkatesh, Vijayalakshmi Sathi, Pragya Deo Sharma, Abhishek Paul
      Journal of Clinical Neonatology 2017 6(3):198-199
      A 15-day-old late preterm female baby weighing 2.6 kg was brought to the emergency room with hypoxic respiratory failure. Bedside echocardiography demonstrated reversal of flow in the descending aorta. Computed tomography angiography was performed and showed arteriovenous fistula between brachiocephalic artery and beginning of superior vena cava. Parents were counseled about the embolization of fistula. Parents refused to consent for the procedure and the baby was discharged against the medical advice.
      Citation: Journal of Clinical Neonatology 2017 6(3):198-199
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_30_17
      Issue No: Vol. 6, No. 3 (2017)
       
  • BRCA1-associated ataxia telangiectasia mutated activation-1 mutation: An
           addition to the early infantile epileptic encephalopathy panel

    • Authors: Anaita Udwadia Hegde, Kishore Pratap Sanghvi, Purva Keni Karnavat, Anil B Jalan
      Pages: 200 - 204
      Abstract: Anaita Udwadia Hegde, Kishore Pratap Sanghvi, Purva Keni Karnavat, Anil B Jalan
      Journal of Clinical Neonatology 2017 6(3):200-204
      We describe a 3-month-old female child born to third degree consanguineous Indian parents with progressive epileptic encephalopathy (EE), microcephaly, and generalized hypertonia. Whole exome sequencing revealed homozygous variant in the BRCA1-associated ataxia telangiectasia mutated activation-1 (BRAT1) gene. Homozygous and compound heterozygous BRAT1 mutations have been described in patients with lethal neonatal rigidity and multifocal seizure syndrome (MIM# 614498). BRAT1 acts as a regulator of cellular proliferation and migration and is required for mitochondrial function. This case highlights the potential of next generation technologies for the diagnosis of rare genetic diseases, including EE of infancy. To our knowledge, this is the first case of BRAT1 mutation from Indian subcontinent.
      Citation: Journal of Clinical Neonatology 2017 6(3):200-204
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_32_17
      Issue No: Vol. 6, No. 3 (2017)
       
  • Congenital idiopathic chylothorax: A very rare case

    • Authors: JD Rawat, Sudhir Singh, Gurmeet Singh, Digamber Chaubey
      Pages: 205 - 207
      Abstract: JD Rawat, Sudhir Singh, Gurmeet Singh, Digamber Chaubey
      Journal of Clinical Neonatology 2017 6(3):205-207
      Chylothorax is a very rare cause of respiratory distress in the neonates, defined as a collection of chyle in the pleural space. Causes of chylothorax in neonates are congenital lymphatic malformations, associated syndrome or birth trauma. Here, we are presenting a neonate presented with severe respiratory distress require intubation and ventilator support and on evaluation no cause of chylothorax found. Baby managed with intercostal drainage and octreotide, improved and asymptomatic in 8 months of follow-up.
      Citation: Journal of Clinical Neonatology 2017 6(3):205-207
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_42_17
      Issue No: Vol. 6, No. 3 (2017)
       
  • Congenital chylothorax in a late preterm neonate associated with hydrops
           fetalis and successful treatment with octreotide and pleurodesis with
           betadine

    • Authors: Prakash Champakbhai Vaghela, Hiral Mangukiya
      Pages: 208 - 210
      Abstract: Prakash Champakbhai Vaghela, Hiral Mangukiya
      Journal of Clinical Neonatology 2017 6(3):208-210
      Congenital chylothorax is an accumulation of chyle in the pleural space that may present in neonatal period with respiratory distress. A 35-week preterm who presented with massive congenital chylothorax complicated with hydrops fetalis. The neonate was treated successfully by total parenteral nutrition, octreotide, and pleurodesis with betadine. Pleurodesis with betadine seems to be effective in the treatment of congenital chylothorax.
      Citation: Journal of Clinical Neonatology 2017 6(3):208-210
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_47_17
      Issue No: Vol. 6, No. 3 (2017)
       
  • Vein of galen malformation in a neonate: An octopus in the brain

    • Authors: Iyer Harohalli Venkatesh, Lakshmi Venkatesha
      Pages: 211 - 212
      Abstract: Iyer Harohalli Venkatesh, Lakshmi Venkatesha
      Journal of Clinical Neonatology 2017 6(3):211-212

      Citation: Journal of Clinical Neonatology 2017 6(3):211-212
      PubDate: Tue,11 Jul 2017
      DOI: 10.4103/jcn.JCN_123_16
      Issue No: Vol. 6, No. 3 (2017)
       
 
 
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