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Publisher: Medknow Publishers   (Total: 426 journals)

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Showing 1 - 200 of 426 Journals sorted alphabetically
Acta Medica Intl.     Open Access   (SJR: 0.101, CiteScore: 0)
Advanced Arab Academy of Audio-Vestibulogy J.     Open Access  
Advanced Biomedical Research     Open Access  
Advances in Human Biology     Open Access   (Followers: 3)
Advances in Skeletal Muscle Function Assessment     Open Access  
African J. for Infertility and Assisted Conception     Open Access  
African J. of Medical and Health Sciences     Open Access   (Followers: 2)
African J. of Paediatric Surgery     Open Access   (Followers: 7, SJR: 0.25, CiteScore: 1)
African J. of Trauma     Open Access   (Followers: 1)
Ain-Shams J. of Anaesthesiology     Open Access   (Followers: 3)
Al-Azhar Assiut Medical J.     Open Access  
Al-Basar Intl. J. of Ophthalmology     Open Access   (Followers: 1)
Alexandria J. of Pediatrics     Open Access  
Ancient Science of Life     Open Access   (Followers: 5)
Anesthesia : Essays and Researches     Open Access   (Followers: 10)
Annals of African Medicine     Open Access   (Followers: 1, SJR: 0.258, CiteScore: 1)
Annals of Bioanthropology     Open Access   (Followers: 4)
Annals of Cardiac Anaesthesia     Open Access   (Followers: 14, SJR: 0.308, CiteScore: 1)
Annals of Indian Academy of Neurology     Open Access   (Followers: 3, SJR: 0.434, CiteScore: 1)
Annals of Indian Academy of Otorhinolaryngology Head and Neck Surgery     Open Access  
Annals of Indian Psychiatry     Open Access  
Annals of Maxillofacial Surgery     Open Access   (Followers: 6)
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 9, SJR: 0.352, CiteScore: 1)
Annals of Saudi Medicine     Open Access   (SJR: 0.238, CiteScore: 1)
Annals of Thoracic Medicine     Open Access   (Followers: 6, SJR: 0.524, CiteScore: 1)
Annals of Tropical Medicine and Public Health     Open Access   (Followers: 13, SJR: 0.152, CiteScore: 0)
Annals of Tropical Pathology     Open Access  
Apollo Medicine     Open Access  
APOS Trends in Orthodontics     Open Access  
Arab J. of Interventional Radiology     Open Access  
Archives of Cardiovascular Imaging     Open Access   (Followers: 1, SJR: 0.187, CiteScore: 0)
Archives of Intl. Surgery     Open Access   (Followers: 10, SJR: 0.302, CiteScore: 1)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Archives of Medicine and Surgery     Open Access  
Archives of Pharmacy Practice     Open Access   (Followers: 6, SJR: 0.102, CiteScore: 0)
Archives of Trauma Research     Open Access   (Followers: 3, SJR: 0.37, CiteScore: 2)
Asia Pacific J. of Clinical Trials : Nervous System Diseases     Open Access  
Asia-Pacific J. of Oncology Nursing     Open Access   (Followers: 5)
Asian J. of Andrology     Open Access   (Followers: 1, SJR: 0.856, CiteScore: 2)
Asian J. of Neurosurgery     Open Access   (Followers: 2)
Asian J. of Oncology     Open Access   (Followers: 1)
Asian J. of Transfusion Science     Open Access   (Followers: 1, SJR: 0.35, CiteScore: 1)
Asian Pacific J. of Reproduction     Open Access   (SJR: 0.227, CiteScore: 1)
Asian Pacific J. of Tropical Biomedicine     Open Access   (Followers: 2, SJR: 0.491, CiteScore: 2)
Asian Pacific J. of Tropical Medicine     Open Access   (Followers: 1, SJR: 0.561, CiteScore: 2)
Astrocyte     Open Access  
Avicenna J. of Medicine     Open Access   (Followers: 1)
AYU : An international quarterly journal of research in Ayurveda     Open Access   (Followers: 6)
Benha Medical J.     Open Access  
Biomedical and Biotechnology Research J.     Open Access  
BLDE University J. of Health Sciences     Open Access  
Brain Circulation     Open Access   (Followers: 1)
Bulletin of Faculty of Physical Therapy     Open Access   (Followers: 1)
Canadian J. of Rural Medicine     Full-text available via subscription   (SJR: 0.202, CiteScore: 0)
Cancer Translational Medicine     Open Access   (Followers: 2)
Cardiology Plus     Open Access  
Chinese Medical J.     Open Access   (Followers: 10, SJR: 0.52, CiteScore: 1)
CHRISMED J. of Health and Research     Open Access   (Followers: 2)
Clinical Cancer Investigation J.     Open Access  
Clinical Dermatology Review     Open Access   (Followers: 3)
Clinical Trials in Degenerative Diseases     Open Access  
Clinical Trials in Orthopedic Disorders     Open Access  
Community Acquired Infection     Open Access  
Conservation and Society     Open Access   (Followers: 10, SJR: 0.811, CiteScore: 2)
Contemporary Clinical Dentistry     Open Access   (Followers: 4, SJR: 0.353, CiteScore: 1)
Current Medical Issues     Open Access   (Followers: 1)
CytoJ.     Open Access   (Followers: 2, SJR: 0.543, CiteScore: 1)
Delta J. of Ophthalmology     Open Access  
Dental Hypotheses     Open Access   (Followers: 3, SJR: 0.152, CiteScore: 0)
Dental Research J.     Open Access   (Followers: 11, SJR: 0.416, CiteScore: 1)
Dentistry and Medical Research     Open Access  
Digital Medicine     Open Access  
Drug Development and Therapeutics     Open Access  
Education for Health     Open Access   (Followers: 6, SJR: 0.242, CiteScore: 0)
Egyptian J. of Bronchology     Open Access  
Egyptian J. of Cardiothoracic Anesthesia     Open Access  
Egyptian J. of Cataract and Refractive Surgery     Open Access   (Followers: 1, SJR: 1.799, CiteScore: 2)
Egyptian J. of Chest Diseases and Tuberculosis     Open Access   (Followers: 3, SJR: 0.155, CiteScore: 0)
Egyptian J. of Dermatology and Venerology     Open Access   (Followers: 1)
Egyptian J. of Haematology     Open Access   (Followers: 1)
Egyptian J. of Internal Medicine     Open Access   (Followers: 1)
Egyptian J. of Neurology, Psychiatry and Neurosurgery     Open Access   (Followers: 1, SJR: 0.127, CiteScore: 0)
Egyptian J. of Obesity, Diabetes and Endocrinology     Open Access   (Followers: 1)
Egyptian J. of Otolaryngology     Open Access   (Followers: 2)
Egyptian J. of Psychiatry     Open Access   (Followers: 2)
Egyptian J. of Surgery     Open Access   (Followers: 1)
Egyptian Nursing J.     Open Access  
Egyptian Orthopaedic J.     Open Access   (Followers: 2)
Egyptian Pharmaceutical J.     Open Access  
Egyptian Retina J.     Open Access  
Egyptian Rheumatology and Rehabilitation     Open Access  
Endodontology     Open Access  
Endoscopic Ultrasound     Open Access   (SJR: 0.822, CiteScore: 2)
Environmental Disease     Open Access   (Followers: 3)
Eurasian J. of Pulmonology     Open Access  
European J. of Dentistry     Open Access   (Followers: 2, SJR: 0.749, CiteScore: 2)
European J. of General Dentistry     Open Access   (Followers: 1, SJR: 0.12, CiteScore: 0)
European J. of Prosthodontics     Open Access   (Followers: 3)
European J. of Psychology and Educational Studies     Open Access   (Followers: 11, SJR: 0.113, CiteScore: 0)
Fertility Science and Research     Open Access  
Formosan J. of Surgery     Open Access   (SJR: 0.112, CiteScore: 0)
Genome Integrity     Open Access   (Followers: 2, SJR: 0.153, CiteScore: 0)
Glioma     Open Access  
Global J. of Transfusion Medicine     Open Access   (Followers: 1)
Gynecology and Minimally Invasive Therapy     Open Access   (SJR: 0.311, CiteScore: 1)
Hamdan Medical J.     Open Access  
Heart and Mind     Open Access  
Heart India     Open Access   (Followers: 1)
Heart Views     Open Access   (Followers: 2)
Hepatitis B Annual     Open Access   (Followers: 3)
Ibnosina J. of Medicine and Biomedical Sciences     Open Access  
IJS Short Reports     Open Access  
Imam J. of Applied Sciences     Open Access  
Indian Dermatology Online J.     Open Access   (Followers: 3)
Indian J. of Allergy, Asthma and Immunology     Open Access   (Followers: 1)
Indian J. of Anaesthesia     Open Access   (Followers: 7, SJR: 0.478, CiteScore: 1)
Indian J. of Burns     Open Access   (Followers: 1)
Indian J. of Cancer     Open Access   (Followers: 1, SJR: 0.361, CiteScore: 1)
Indian J. of Cerebral Palsy     Open Access   (Followers: 1)
Indian J. of Community Medicine     Open Access   (Followers: 2, SJR: 0.37, CiteScore: 1)
Indian J. of Critical Care Medicine     Open Access   (Followers: 4, SJR: 0.604, CiteScore: 1)
Indian J. of Dental Research     Open Access   (Followers: 4, SJR: 0.266, CiteScore: 1)
Indian J. of Dental Sciences     Open Access  
Indian J. of Dentistry     Open Access   (Followers: 1)
Indian J. of Dermatology     Open Access   (Followers: 2, SJR: 0.468, CiteScore: 1)
Indian J. of Dermatology, Venereology and Leprology     Open Access   (Followers: 4, SJR: 0.445, CiteScore: 1)
Indian J. of Dermatopathology and Diagnostic Dermatology     Open Access  
Indian J. of Drugs in Dermatology     Open Access   (Followers: 1, SJR: 0.791, CiteScore: 1)
Indian J. of Endocrinology and Metabolism     Open Access   (Followers: 4, SJR: 0.568, CiteScore: 1)
Indian J. of Health Sciences     Open Access   (Followers: 2)
Indian J. of Medical and Paediatric Oncology     Open Access   (SJR: 0.425, CiteScore: 1)
Indian J. of Medical Microbiology     Open Access   (Followers: 1, SJR: 0.503, CiteScore: 1)
Indian J. of Medical Research     Open Access   (Followers: 4, SJR: 0.656, CiteScore: 1)
Indian J. of Medical Sciences     Open Access   (Followers: 2, SJR: 0.102, CiteScore: 0)
Indian J. of Multidisciplinary Dentistry     Open Access   (Followers: 1)
Indian J. of Nephrology     Open Access   (Followers: 2, SJR: 0.347, CiteScore: 1)
Indian J. of Nuclear Medicine     Open Access   (Followers: 2, SJR: 0.23, CiteScore: 0)
Indian J. of Occupational and Environmental Medicine     Open Access   (Followers: 3, SJR: 0.225, CiteScore: 1)
Indian J. of Ophthalmology     Open Access   (Followers: 4, SJR: 0.498, CiteScore: 1)
Indian J. of Oral Health and Research     Open Access  
Indian J. of Oral Sciences     Open Access   (Followers: 1)
Indian J. of Orthopaedics     Open Access   (Followers: 8, SJR: 0.392, CiteScore: 1)
Indian J. of Otology     Open Access   (Followers: 1, SJR: 0.199, CiteScore: 0)
Indian J. of Paediatric Dermatology     Open Access   (Followers: 2)
Indian J. of Pain     Open Access   (Followers: 1)
Indian J. of Palliative Care     Open Access   (Followers: 5, SJR: 0.454, CiteScore: 1)
Indian J. of Pathology and Microbiology     Open Access   (Followers: 2, SJR: 0.276, CiteScore: 1)
Indian J. of Pharmacology     Open Access   (SJR: 0.412, CiteScore: 1)
Indian J. of Plastic Surgery     Open Access   (Followers: 12, SJR: 0.311, CiteScore: 0)
Indian J. of Psychiatry     Open Access   (Followers: 3, SJR: 0.408, CiteScore: 1)
Indian J. of Psychological Medicine     Open Access   (SJR: 0.368, CiteScore: 1)
Indian J. of Public Health     Open Access   (Followers: 1)
Indian J. of Radiology and Imaging     Open Access   (Followers: 4)
Indian J. of Research in Homoeopathy     Open Access  
Indian J. of Respiratory Care     Open Access  
Indian J. of Rheumatology     Open Access   (SJR: 0.119, CiteScore: 0)
Indian J. of Sexually Transmitted Diseases and AIDS     Open Access   (Followers: 2, SJR: 0.34, CiteScore: 0)
Indian J. of Social Psychiatry     Open Access   (Followers: 2)
Indian J. of Transplantation     Open Access  
Indian J. of Urology     Open Access   (Followers: 3, SJR: 0.434, CiteScore: 1)
Indian J. of Vascular and Endovascular Surgery     Open Access   (Followers: 2)
Indian Spine J.     Open Access  
Industrial Psychiatry J.     Open Access   (Followers: 2)
Intervention     Open Access   (Followers: 1)
Intl. Archives of Health Sciences     Open Access  
Intl. J. of Abdominal Wall and Hernia Surgery     Open Access   (Followers: 1)
Intl. J. of Academic Medicine     Open Access  
Intl. J. of Advanced Medical and Health Research     Open Access  
Intl. J. of Applied and Basic Medical Research     Open Access  
Intl. J. of Clinical and Experimental Physiology     Open Access   (Followers: 1)
Intl. J. of Clinicopathological Correlation     Open Access  
Intl. J. of Community Dentistry     Open Access  
Intl. J. of Critical Illness and Injury Science     Open Access   (Followers: 1, SJR: 0.192, CiteScore: 0)
Intl. J. of Educational and Psychological Researches     Open Access   (Followers: 4)
Intl. J. of Environmental Health Engineering     Open Access   (Followers: 1)
Intl. J. of Forensic Odontology     Open Access   (Followers: 1)
Intl. J. of Green Pharmacy     Open Access   (Followers: 3, SJR: 0.142, CiteScore: 0)
Intl. J. of Growth Factors and Stem Cells in Dentistry     Open Access  
Intl. J. of Health & Allied Sciences     Open Access   (Followers: 3)
Intl. J. of Health System and Disaster Management     Open Access   (Followers: 3)
Intl. J. of Heart Rhythm     Open Access  
Intl. J. of Medicine and Public Health     Open Access   (Followers: 6)
Intl. J. of Mycobacteriology     Open Access   (SJR: 0.535, CiteScore: 1)
Intl. J. of Noncommunicable Diseases     Open Access  
Intl. J. of Nutrition, Pharmacology, Neurological Diseases     Open Access   (Followers: 4, SJR: 0.17, CiteScore: 0)
Intl. J. of Oral Health Sciences     Open Access   (Followers: 2)
Intl. J. of Orofacial Biology     Open Access   (Followers: 1)
Intl. J. of Orofacial Research     Open Access   (Followers: 1)
Intl. J. of Orthodontic Rehabilitation     Open Access  
Intl. J. of Pedodontic Rehabilitation     Open Access  
Intl. J. of Pharmaceutical Investigation     Open Access   (Followers: 1)
Intl. J. of Preventive Medicine     Open Access   (Followers: 1, SJR: 0.623, CiteScore: 1)
Intl. J. of Shoulder Surgery     Open Access   (Followers: 5, SJR: 0.653, CiteScore: 1)
Intl. J. of the Cardiovascular Academy     Open Access   (SJR: 0.105, CiteScore: 0)
Intl. J. of Trichology     Open Access   (SJR: 0.4, CiteScore: 1)
Intl. J. of Yoga     Open Access   (Followers: 15)
Intl. J. of Yoga : Philosophy, Psychology and Parapsychology     Open Access   (Followers: 6)
Iranian J. of Nursing and Midwifery Research     Open Access   (Followers: 3)

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Journal Cover
Indian Journal of Medical Research
Journal Prestige (SJR): 0.656
Citation Impact (citeScore): 1
Number of Followers: 4  

  This is an Open Access Journal Open Access journal
ISSN (Print) 0971-5916
Published by Medknow Publishers Homepage  [426 journals]
  • Evidence-based global cardiovascular disease control priority
           interventions

    • Authors: Mark D Huffman, PP Mohanan, Dorairaj Prabhakaran
      Pages: 247 - 250
      Abstract: Mark D Huffman, PP Mohanan, Dorairaj Prabhakaran
      Indian Journal of Medical Research 2018 148(3):247-250

      Citation: Indian Journal of Medical Research 2018 148(3):247-250
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_1482_18
      Issue No: Vol. 148, No. 3 (2018)
       
  • Ketogenic diets: Boon or bane?

    • Authors: Joshi Shilpa, Viswanathan Mohan
      Pages: 251 - 253
      Abstract: Joshi Shilpa, Viswanathan Mohan
      Indian Journal of Medical Research 2018 148(3):251-253

      Citation: Indian Journal of Medical Research 2018 148(3):251-253
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_1666_18
      Issue No: Vol. 148, No. 3 (2018)
       
  • Pancreatic ductal adenocarcinoma: Role of chemotherapy & future
           perspectives

    • Authors: Akash Tiwari, Lalit Kumar
      Pages: 254 - 257
      Abstract: Akash Tiwari, Lalit Kumar
      Indian Journal of Medical Research 2018 148(3):254-257

      Citation: Indian Journal of Medical Research 2018 148(3):254-257
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_615_18
      Issue No: Vol. 148, No. 3 (2018)
       
  • Department of Health Research-Health Technology Assessment (DHR-HTA)
           database: National prospective register of studies under HTAIn

    • Authors: Shalu Jain, Kavitha Rajshekar, Aamir Sohail, Vijay Kumar Gauba
      Pages: 258 - 261
      Abstract: Shalu Jain, Kavitha Rajshekar, Aamir Sohail, Vijay Kumar Gauba
      Indian Journal of Medical Research 2018 148(3):258-261

      Citation: Indian Journal of Medical Research 2018 148(3):258-261
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_1613_18
      Issue No: Vol. 148, No. 3 (2018)
       
  • A fascinating story of the discovery & development of biologicals for
           use in clinical medicine

    • Authors: Anand N Malaviya, Narinder K Mehra
      Pages: 263 - 278
      Abstract: Anand N Malaviya, Narinder K Mehra
      Indian Journal of Medical Research 2018 148(3):263-278
      A young physician starting a fresh career in medicine in this millennium would hardly stop to think about the genesis of a particular biological drug that he/she will be prescribing for a patient evaluated in the morning outpatient department. For him/her, this is now routine, and the question of ‘Who’, ‘How’ and ‘When’ about these biologicals would be the last thing on their mind. However, for those who came to the medical profession in the 1950s, 1960s and 1970s, these targeted drugs are nothing short of ‘miracles’. It would be a fascinating story for the young doctor to learn about the long journey that the dedicated biomedical scientists of yesteryears took to reach the final destination of producing such wonder drugs. The story is much like an interesting novel, full of twists and turns, heart-breaking failures and glorious successes. The biologicals acting as ‘targeted therapy’ have not only changed the natural history of a large number of incurable/uncontrollable diseases but have also transformed the whole approach towards drug development. From the classical empirical process, there is now a complete shift towards understanding the disease pathobiology focusing on the dysregulated molecule(s), targeting them with greater precision and aiming for better results. Seminal advances in understanding the disease mechanism, development of remarkably effective new technologies, greater knowledge of the human genome and genetic medicine have all made it possible to reach the stage where artificially developed ‘targeted’ drugs are now therapeutically used in routine clinical medicine.
      Citation: Indian Journal of Medical Research 2018 148(3):263-278
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_1471_18
      Issue No: Vol. 148, No. 3 (2018)
       
  • National ethical guidelines for biomedical & health research involving
           human participants, 2017: A commentary

    • Authors: Roli Mathur, Soumya Swaminathan
      Pages: 279 - 283
      Abstract: Roli Mathur, Soumya Swaminathan
      Indian Journal of Medical Research 2018 148(3):279-283
      The Indian Council of Medical Research (ICMR) has been at the forefront in setting up the ethical guidance for the conduct of biomedical and health research in India. The latest version of National Guidelines for Biomedical and Health Research Involving Human Participants, 2017 was planned in order to provide a more detailed guidance to the existing topics in view of emerging ethical concerns and to add a number of newer areas in which guidance was lacking. The scope of the guidelines has been expanded to include socio-behavioural research related to health and research involving biological material and datasets. The guidelines have 12 sections which cover a wide range of topics and areas of research. The first six sections are more generic, applying to all types of biomedical and health research, while the next six sections are more subject specific. The guidelines have been revised in consultation with a large number of experts and stakeholders and went through an exhaustive process stretching over a period of two years in its drafting, review, consultation and finalisation. This commentary seeks to explain the process and key components of the Guidelines.
      Citation: Indian Journal of Medical Research 2018 148(3):279-283
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/0971-5916.245303
      Issue No: Vol. 148, No. 3 (2018)
       
  • Experience with non-cremophor-based paclitaxel-gemcitabine regimen in
           advanced pancreatic cancer: Results from a single tertiary cancer centre

    • Authors: Vikas Ostwal, Arvind Sahu, Saurabh Zanwar, Lingaraj Nayak, Shailesh V Shrikhande, Nitin Shetty, Sudeep Gupta, Anant Ramaswamy
      Pages: 284 - 290
      Abstract: Vikas Ostwal, Arvind Sahu, Saurabh Zanwar, Lingaraj Nayak, Shailesh V Shrikhande, Nitin Shetty, Sudeep Gupta, Anant Ramaswamy
      Indian Journal of Medical Research 2018 148(3):284-290
      Background & objectives: Gemcitabine combined with non-cremophor-based paclitaxel is one of the standards of care in advanced inoperable pancreatic cancer. This study was undertaken to retrospectively evaluate real world non-trial outcomes with this combination.Methods: Patients with histologically proven advanced inoperable pancreatic adenocarcinoma (PDAC), treated with non-cremophor-based paclitaxel-gemcitabine combination (PG) (gemcitabine-nanoxel or gemcitabine-abraxane) between January 2012 and June 2015, were retrospectively analyzed. Response assessment was done every 8-12 wk with computed tomography scan and responses were measured as per the Response Evaluation Criteria in Solid Tumours 1.1 criteria where feasible. Toxicity was recorded as per the Common Terminology Criteria for Adverse Events (CTCAE) v4 criteria. Progression-free survival (PFS) and overall survival (OS) were calculated using the Kaplan-Meier method.Results: A total of 78 patients with PDAC were treated with the combination. Of these, 83.3 per cent of patients had metastatic disease. The median number of chemotherapy cycles administered was three. The objective response rate for the whole group was 30.8 per cent. Grade III/IV toxicities were seen in 35.9 per cent of patients. Median PFS was 5.6 months and median OS was 11.6 months.Interpretation & conclusions: Non-cremophor-based paclitaxel in combination with gemcitabine appeared efficacious for advanced pancreatic cancers in routine clinical practice. Within the confines of a single-centre retrospective analysis, gemcitabine-nanoxel and gemcitabine-abraxane appeared to have similar efficacy and toxicity in advanced pancreatic cancers.
      Citation: Indian Journal of Medical Research 2018 148(3):284-290
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_249_17
      Issue No: Vol. 148, No. 3 (2018)
       
  • Prevalence, clinical & biochemical correlates of non-alcoholic fatty
           liver disease in overweight adolescents

    • Authors: Vandana Jain, Manisha Jana, Babita Upadhyay, Nayeem Ahmad, Oshima Jain, Ashish Datt Upadhyay, Lakshmy Ramakrishnan, Naval K Vikram
      Pages: 291 - 301
      Abstract: Vandana Jain, Manisha Jana, Babita Upadhyay, Nayeem Ahmad, Oshima Jain, Ashish Datt Upadhyay, Lakshmy Ramakrishnan, Naval K Vikram
      Indian Journal of Medical Research 2018 148(3):291-301
      Background & objectives: Non-alcoholic fatty liver disease (NAFLD) characterized by excessive accumulation of fat in the liver, which can progress to inflammation, and cirrhosis, has emerged as an important complication of obesity in adults as well as children. This study was undertaken to assess the prevalence of NAFLD and its correlation with clinical and biochemical parameters in overweight Indian adolescents.Methods: In this cross-sectional study, 218 overweight adolescents aged 10 to 16 yr and their parents were included. Measurements included anthropometry, ultrasonography to diagnose NAFLD, fasting glucose, aspartate aminotransferase (AST), alanine aminotransferase (ALT) and lipids for adolescents and parents, and additional parameters of blood pressure, body fat percentage (BF%), fasting insulin, apolipoprotein C3, tumour necrosis factor-α and adiponectin for adolescents. The variables were compared between adolescents with and without NAFLD, and logistic regression analysis was performed.Results: Mean age and body mass index (BMI)SD score (SDS) were 11.9±1.6 yr and 2.3±1.1, respectively. NAFLD was seen in 62.5 per cent of the adolescents. The prevalence of NAFLD in the parents was similar among the adolescents with and without NAFLD, while BMI and waist circumference SDS, BF per cent, blood pressure (BP), ALT, AST, insulin and homeostatic model assessment of insulin resistance (HOMA-IR) were significantly higher in the adolescents with NAFLD. On multiple logistic regression, abdominal obesity, HOMA-IR and BF per cent were independently associated with NAFLD with odds ratios (95% confidence interval) of 2.77 (1.40-5.47), 2.21 (1.16-4.21) and 2.17 (1.12-4.22), respectively.Interpretation & conclusions: NAFLD was noted among nearly two-thirds of the overweight adolescents. An independent association was observed between abdominal obesity, HOMA-IR and body fat percentage and NAFLD in overweight adolescents.
      Citation: Indian Journal of Medical Research 2018 148(3):291-301
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_1966_16
      Issue No: Vol. 148, No. 3 (2018)
       
  • Addition of power Doppler to grey scale transvaginal ultrasonography for
           improving the prediction of endometrial pathology in perimenopausal women
           with abnormal uterine bleeding

    • Authors: P Veena, Dasabharathi Baskaran, Dilip Kumar Maurya, NS Kubera, Jayalakshmi Dorairaj
      Pages: 302 - 308
      Abstract: P Veena, Dasabharathi Baskaran, Dilip Kumar Maurya, NS Kubera, Jayalakshmi Dorairaj
      Indian Journal of Medical Research 2018 148(3):302-308
      Background & objectives: Transvaginal ultrasonography (TVS) is a non-invasive procedure and can be used as a screening tool among women with abnormal uterine bleeding (AUB). Power Doppler is useful in depicting the vascular architecture better than the conventional Doppler. Hence, this study was conducted to evaluate whether addition of power Doppler to grey scale TVS can replace invasive hysteroscopy for the prediction of endometrial pathology in perimenopausal women with AUB.Methods: One hundred women (>45 yr) with perimenopausal AUB underwent evaluation with TVS, power Doppler and hysteroscopy-guided biopsy after a detailed history and examination. Histopathology was considered as gold standard and other tools such as grey scale TVS with power Doppler and hysteroscopy were compared with it.Results: Fifty six per cent women had no vascularity on power Doppler. Among those who had vascularity, the vascular patterns noted were single-vessel in 18 per cent, scattered-vessel in 15 per cent and multiple-vessel in 11 per cent. The sensitivity, specificity, positive predictive value and negative predictive value of TVS-endometrial thickness with power Doppler in detecting hyperplasia were 50, 86.5, 13.3 and 97.6 per cent, respectively, whereas the same for hysteroscopy were 100, 97.6, 88.1 and 100 per cent, respectively.Interpretation & conclusions: Addition of power Doppler to grey scale TVS improved the specificity and negative predictive value almost comparable to hysteroscopy for evaluation of AUB, but sensitivity and positive predictive value remained poor.
      Citation: Indian Journal of Medical Research 2018 148(3):302-308
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_96_17
      Issue No: Vol. 148, No. 3 (2018)
       
  • Labour & delivery monitoring patterns in facility births across five
           districts of India: A cross-sectional observational study

    • Authors: Shalini Singh, Jyotika A Kashyap, Nomita Chandhiok, Vipin Kumar, Vishwajeet Singh, Richa Goel, for an ICMR-UNFPA Task Force study on reducing maternal mortality; early postpartum care*
      Pages: 309 - 316
      Abstract: Shalini Singh, Jyotika A Kashyap, Nomita Chandhiok, Vipin Kumar, Vishwajeet Singh, Richa Goel, for an ICMR-UNFPA Task Force study on reducing maternal mortality and morbidity through promotion of evidence based intrapartum and early postpartum care*
      Indian Journal of Medical Research 2018 148(3):309-316
      Background & objectives: India has recorded a marked increase in facility births due to government's conditional cash benefit scheme initiated in 2005. However, concerns have been raised regarding the need for improvement in the quality of care at facilities. Here we report the monitoring patterns during labour and delivery documented by direct observation in reference to the government's evidence-based guidelines on skilled birth attendance in five districts of India.Methods: A cross-sectional study design with multistage sampling was used for observation of labour and delivery processes of low-risk women with singleton pregnancy in five districts of the country. Trained research staff recorded the findings on pre-tested case record sheets.Results: A total of 1479 women were observed during active first stage of labour and delivery in 55 facilities. The overall frequency of monitoring of temperature, pulse and blood pressure was low at all facilities. The frequency of monitoring uterine contractions and foetal heart sounds was less than the expected norm, while the frequency of vaginal examinations was high at all levels of facilities. Partograph plotting was done in only 15.8 per cent deliveries, and labour was augmented in about half of the cases.Interpretation & conclusions: The findings of our study point towards a need for improvement in monitoring of maternal and foetal parameters during labour and delivery in facility births and to improve adherence to government guidelines for skilled birth attendance.
      Citation: Indian Journal of Medical Research 2018 148(3):309-316
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_103_18
      Issue No: Vol. 148, No. 3 (2018)
       
  • Association of reduced count of interleukin-13-producing cells in breast
           milk with atopic dermatitis in infancy

    • Authors: Sepideh Moradkhani, Abdollah Jafarzadeh, Nasrin Bazargan-Harandi, Mohammad Reza Baneshi, Mohammad Mahdi Mohammadi
      Pages: 317 - 322
      Abstract: Sepideh Moradkhani, Abdollah Jafarzadeh, Nasrin Bazargan-Harandi, Mohammad Reza Baneshi, Mohammad Mahdi Mohammadi
      Indian Journal of Medical Research 2018 148(3):317-322
      Background & objectives: Atopic dermatitis (AD) is one of the most common pathologic conditions of skin in children. The effect of breastfeeding on the risk of AD remains controversial. The aim of this study was to determine the counts of cytokine-producing cells in the mothers' breast milk of infants with and without AD to assess association, if any.Methods: Breast milk samples (10 ml) were obtained from mothers of 25 infants with AD and of 26 healthy infants as a control group. The number of cytokine-producing cells including interferon-gamma (IFN-γ), tumour necrosis factor-alpha (TNF-α), interleukin-13 (IL-13) and IL-4 in the milk samples was determined using an enzyme-linked immunospot assay technique.Results: The mean of IL-13-producing cells in milk was significantly lower in mothers of AD-affected infants in comparison with mothers of normal infants (324.91±255.45 vs. 538.93±465.39, P<0.05). There were no significant differences between mothers of infants with and without AD regarding milk count of IFN-γ-, TNF-α- and IL-4-producing cells.Interpretation & conclusions: Our results showed lower number of IL-13-producing cells in milk of mothers of infants with AD. Therefore, lower count of IL-13-producing cells in mothers' milk may confer a susceptibility to AD. Further studies with a large number of samples need to be done to confirm our findings.
      Citation: Indian Journal of Medical Research 2018 148(3):317-322
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_1682_16
      Issue No: Vol. 148, No. 3 (2018)
       
  • High frequency of HPV16 European variant E350G among Mexican women from
           Sinaloa

    • Authors: Elisa Anali Camacho-Ureta, Roc&#237;o Susana Mendez-Mart&#237;nez, Salvador V&#225;zquez-Vega, Ulises Osuna Mart&#237;nez, Rosalinda S&#225;nchez Arenas, Hip&#243;lito Castillo-Ureta, Ignacio Osuna Ram&#237;rez, Edith Hilario Torres Montoya, H&#233;ctor Samuel L&#243;pez Moreno, Alejandro Garc&#237;a-Carranca, Jos&#233; Guadalupe Rend&#243;n-Maldonado
      Pages: 323 - 328
      Abstract: Elisa Anali Camacho-Ureta, Rocío Susana Mendez-Martínez, Salvador Vázquez-Vega, Ulises Osuna Martínez, Rosalinda Sánchez Arenas, Hipólito Castillo-Ureta, Ignacio Osuna Ramírez, Edith Hilario Torres Montoya, Héctor Samuel López Moreno, Alejandro García-Carranca, José Guadalupe Rendón-Maldonado
      Indian Journal of Medical Research 2018 148(3):323-328
      Background & objectives: Human papillomavirus (HPV) infections play a crucial role in the aetiology of cervical cancer (CC), and HPV16 is the primary viral genotype associated with CC. A number of variants of the HPV16 E6 gene are involved in the progression of CC, differing in their prevalence and biological and biochemical properties. This study was designed to determine the frequency of HPV types 16/18 and to identify the presence of HPV16 E6-variants in asymptomatic Mexican women.Methods: A total of 189 cervical Pap smears were collected from women attending public health services in three different cities in Sinaloa, Mexico. Viral DNA was identified by amplification of E6 viral gene fragments using polymerase chain reaction (PCR). Identification of variants was done by sequencing a DNA fragment (321bp) of the HPV16 E6 gene.Results: More than half of the women tested were HPV-positive (52.38%), with HPV16 being the most frequent genotype (21.16%), followed by HPV18 (8.99%). Sequence analysis of the E6-HPV16 PCR products showed that in all cases, the viruses corresponded to European variants. It was further observed that the E350G intra-variant was the most common (>76%).Interpretation & conclusions: This study showed a predominance of European lineage variants of HPV16 among asymptomatic women from Sinaloa, Mexico, predominantly with of the E350G variant. This variant has been shown to be associated with an increased risk of early development of CC. The use of molecular identification of carcinogenic HPV and Pap test screening may be a good strategy for monitoring women to prevent CC.
      Citation: Indian Journal of Medical Research 2018 148(3):323-328
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_61_17
      Issue No: Vol. 148, No. 3 (2018)
       
  • Respiratory viruses in returning Hajj & Umrah pilgrims with acute
           respiratory illness in 2014-2015

    • Authors: Parvaiz A Koul, Hyder Mir, Siddhartha Saha, Mandeep S Chadha, Varsha Potdar, Marc-Alain Widdowson, Renu B Lal, Anand Krishnan
      Pages: 329 - 333
      Abstract: Parvaiz A Koul, Hyder Mir, Siddhartha Saha, Mandeep S Chadha, Varsha Potdar, Marc-Alain Widdowson, Renu B Lal, Anand Krishnan
      Indian Journal of Medical Research 2018 148(3):329-333
      Background & objectives: Respiratory tract infections are common among Hajj and Umrah pilgrims which pose a public health risk of spread of respiratory infections. Influenza has been reported from Indian Hajj and Umrah returning pilgrims, but data on other respiratory pathogens are sparse in India. Here we report the presence of common respiratory viral pathogens in returning Hajj and Umrah pilgrims suffering from acute respiratory illness (ARI) in 2014-2015.Methods: Respiratory specimens (nasopharyngeal and throat swabs) were collected from 300 consenting pilgrims with ARI in the past one week and tested for influenza and Middle East Respiratory Syndrome coronavirus (MERS-CoV) and other respiratory viruses using in-house standardized quantitative real-time reverse-transcription polymerase chain reaction. Clinical features among the pathogen positive and negative patients were compared. The patients received symptomatic treatment and antivirals where appropriate and were followed telephonically to collect data on illness outcome.Results: Ninety seven (32.3%) of the 300 participants were tested positive for any virus, most common being influenza viruses (n=33, 11%). Other respiratory viruses that were detected included human coronaviruses [n=26, 8.7%; OC43 (n=19, 6.3%) and C229E (n=7, 2.3%)], rhinovirus (n=20, 6%), adenoviruses (n=8, 2.6%), parainfluenza viruses (n=7, 2.3%), respiratory syncytial virus (n=3, 1%) and bocaviruses (n=2, 0.6%). Clinical features observed in pathogen positive and pathogen negative patients did not differ significantly. Eighteen influenza positive patients were treated with oseltamivir.Interpretation & conclusions: Pilgrims returning from mass gatherings are often afflicted with respiratory pathogens with a potential to facilitate transmission of respiratory pathogens across international borders. The study reinforces the need for better infection prevention and control measures such as vaccination, health education on cough etiquette and hand hygiene.
      Citation: Indian Journal of Medical Research 2018 148(3):329-333
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_890_17
      Issue No: Vol. 148, No. 3 (2018)
       
  • Courtship activity, copulation & insemination success in a mosquito
           vector fed a herbal aphrodisiac: Implications for sterile insect
           technology

    • Authors: Hamady Dieng, Tomomitsu Satho, Fatimah Abang, Fumio Miake, Fatin A. B. Azman, Nurshilawati A Latip, Nur Ezzati Aliasan, Sabina Noor, Cirilo Nolasco-Hipolito, Abu Hassan Ahmad, Idris A Ghani, Hamdan Ahmad, Wan Fatma Zuharah, Abdul Hafiz A. Majid, Ronald E Morales Vargas, Noppawan P Morales, Siriluck Attrapadung, Gabriel Tonga Noweg
      Pages: 334 - 340
      Abstract: Hamady Dieng, Tomomitsu Satho, Fatimah Abang, Fumio Miake, Fatin A. B. Azman, Nurshilawati A Latip, Nur Ezzati Aliasan, Sabina Noor, Cirilo Nolasco-Hipolito, Abu Hassan Ahmad, Idris A Ghani, Hamdan Ahmad, Wan Fatma Zuharah, Abdul Hafiz A. Majid, Ronald E Morales Vargas, Noppawan P Morales, Siriluck Attrapadung, Gabriel Tonga Noweg
      Indian Journal of Medical Research 2018 148(3):334-340
      Background & objectives: In sterile insect technology (SIT), mating competitiveness is a pre-condition for the reduction of target pest populations and a crucial parameter for judging efficacy. Still, current SIT trials are being hindered by decreased effectiveness due to reduced sexual performance of released males. Here, we explored the possible role of a herbal aphrodisiac in boosting the mating activity of Aedes aegypti.Methods: Males were fed one of two diets in this study: experimental extract of Eurycoma longifolia (MSAs) and sugar only (MSOs). Differences in life span, courtship latency, copulation activity and mating success were examined between the two groups.Results: No deaths occurred among MSA and MSO males. Life span of MSOs was similar to that of MSAs. The courtship latency of MSAs was shorter than that of MSOs (P<0.01). MSAs had greater copulation success than MSOs (P<0.001). In all female treatments, MSAs mated more than MSOs, but the differences in rate were significant only in the highest female density (P<0.05). In MSAs, mating success varied significantly with female density (P<0.01), with the 20-female group (P<0.01) having the lowest rate. Single MSA had better mating success at the two lowest female densities. In MSOs, there were no significant differences in mating success rate between the different female densities.Interpretation & conclusions: Our results suggested that the herbal aphrodisiac, E. longifolia, stimulated the sexual activity of Ae. aegypti and may be useful for improving the mating competitiveness of sterile males, thus improving SIT programmes.
      Citation: Indian Journal of Medical Research 2018 148(3):334-340
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_1604_16
      Issue No: Vol. 148, No. 3 (2018)
       
  • Do the clonally different Escherichia coli isolates causing different
           infections in a HIV positive patient affect the selection of antibiotics
           for their treatment?

    • Authors: Marimuthu Ragavan Rameshkumar, Narasingam Arunagirinathan, Chinnambedu Ravichandran Swathirajan, Ramachandran Vignesh, Pachamuthu Balakrishnan, Sunil Suhas Solomon
      Pages: 341 - 344
      Abstract: Marimuthu Ragavan Rameshkumar, Narasingam Arunagirinathan, Chinnambedu Ravichandran Swathirajan, Ramachandran Vignesh, Pachamuthu Balakrishnan, Sunil Suhas Solomon
      Indian Journal of Medical Research 2018 148(3):341-344

      Citation: Indian Journal of Medical Research 2018 148(3):341-344
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_730_17
      Issue No: Vol. 148, No. 3 (2018)
       
  • Reduction in prevalence of anaemia in pregnant women

    • Authors: Aakriti Gupta, Radhika Kapil, Umesh Kapil
      Pages: 345 - 346
      Abstract: Aakriti Gupta, Radhika Kapil, Umesh Kapil
      Indian Journal of Medical Research 2018 148(3):345-346

      Citation: Indian Journal of Medical Research 2018 148(3):345-346
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_1429_18
      Issue No: Vol. 148, No. 3 (2018)
       
  • Authors&#39; Response

    • Authors: K Kalaivani, Prema Ramachandran
      Pages: 346 - 347
      Abstract: K Kalaivani, Prema Ramachandran
      Indian Journal of Medical Research 2018 148(3):346-347

      Citation: Indian Journal of Medical Research 2018 148(3):346-347
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/0971-5916.245301
      Issue No: Vol. 148, No. 3 (2018)
       
  • Procalcitonin-guided antibiotic usage - addressing heterogeneity in
           meta-analysis

    • Authors: Amit Ravindra Birajdar, Urmila M Thatte, Nithya J Gogtay
      Pages: 348 - 349
      Abstract: Amit Ravindra Birajdar, Urmila M Thatte, Nithya J Gogtay
      Indian Journal of Medical Research 2018 148(3):348-349

      Citation: Indian Journal of Medical Research 2018 148(3):348-349
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_1235_18
      Issue No: Vol. 148, No. 3 (2018)
       
  • Authors&#39; Response

    • Authors: Nusrat Shafiq, Vikas Gautam, AK Pandey, Navjot Kaur, Shubha Garg, H Negi, Sharonjeet Kaur, Pallab Ray, S Malhotra
      Pages: 349 - 350
      Abstract: Nusrat Shafiq, Vikas Gautam, AK Pandey, Navjot Kaur, Shubha Garg, H Negi, Sharonjeet Kaur, Pallab Ray, S Malhotra
      Indian Journal of Medical Research 2018 148(3):349-350

      Citation: Indian Journal of Medical Research 2018 148(3):349-350
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/0971-5916.245302
      Issue No: Vol. 148, No. 3 (2018)
       
  • Langerhans cell histiocytosis

    • Authors: Manish Kumar, Anil S Menon
      Pages: 351 - 352
      Abstract: Manish Kumar, Anil S Menon
      Indian Journal of Medical Research 2018 148(3):351-352

      Citation: Indian Journal of Medical Research 2018 148(3):351-352
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_1988_16
      Issue No: Vol. 148, No. 3 (2018)
       
  • Chronic ulcer with rejected skin graft in a female: Pentazocine-induced
           skin ulcers revisited

    • Authors: Sonali Bajaj, Kabir Sardana
      Pages: 353 - 354
      Abstract: Sonali Bajaj, Kabir Sardana
      Indian Journal of Medical Research 2018 148(3):353-354

      Citation: Indian Journal of Medical Research 2018 148(3):353-354
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_1306_16
      Issue No: Vol. 148, No. 3 (2018)
       
  • Neurological illness in pregnancy: Principles and practice

    • Authors: Sanjeev V Thomas
      Pages: 355 - 356
      Abstract: Sanjeev V Thomas
      Indian Journal of Medical Research 2018 148(3):355-356

      Citation: Indian Journal of Medical Research 2018 148(3):355-356
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_648_17
      Issue No: Vol. 148, No. 3 (2018)
       
  • Investigating infertility

    • Authors: Suneeta Mittal
      Pages: 356 - 357
      Abstract: Suneeta Mittal
      Indian Journal of Medical Research 2018 148(3):356-357

      Citation: Indian Journal of Medical Research 2018 148(3):356-357
      PubDate: Tue,13 Nov 2018
      DOI: 10.4103/ijmr.IJMR_272_18
      Issue No: Vol. 148, No. 3 (2018)
       
 
 
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