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Publisher: Medknow Publishers   (Total: 427 journals)

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Showing 1 - 200 of 427 Journals sorted alphabetically
Acta Medica Intl.     Open Access   (SJR: 0.101, CiteScore: 0)
Advanced Arab Academy of Audio-Vestibulogy J.     Open Access  
Advanced Biomedical Research     Open Access  
Advances in Human Biology     Open Access   (Followers: 4)
Advances in Skeletal Muscle Function Assessment     Open Access  
African J. for Infertility and Assisted Conception     Open Access  
African J. of Medical and Health Sciences     Open Access   (Followers: 2)
African J. of Paediatric Surgery     Open Access   (Followers: 7, SJR: 0.25, CiteScore: 1)
African J. of Trauma     Open Access   (Followers: 1)
Ain-Shams J. of Anaesthesiology     Open Access   (Followers: 3)
Al-Azhar Assiut Medical J.     Open Access  
Al-Basar Intl. J. of Ophthalmology     Open Access   (Followers: 1)
Alexandria J. of Pediatrics     Open Access  
Ancient Science of Life     Open Access   (Followers: 5)
Anesthesia : Essays and Researches     Open Access   (Followers: 10)
Annals of African Medicine     Open Access   (Followers: 2, SJR: 0.258, CiteScore: 1)
Annals of Bioanthropology     Open Access   (Followers: 4)
Annals of Cardiac Anaesthesia     Open Access   (Followers: 14, SJR: 0.308, CiteScore: 1)
Annals of Indian Academy of Neurology     Open Access   (Followers: 3, SJR: 0.434, CiteScore: 1)
Annals of Indian Academy of Otorhinolaryngology Head and Neck Surgery     Open Access  
Annals of Indian Psychiatry     Open Access  
Annals of Maxillofacial Surgery     Open Access   (Followers: 6)
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 12, SJR: 0.352, CiteScore: 1)
Annals of Saudi Medicine     Open Access   (SJR: 0.238, CiteScore: 1)
Annals of Thoracic Medicine     Open Access   (Followers: 6, SJR: 0.524, CiteScore: 1)
Annals of Tropical Medicine and Public Health     Open Access   (Followers: 13, SJR: 0.152, CiteScore: 0)
Annals of Tropical Pathology     Open Access  
Apollo Medicine     Open Access  
APOS Trends in Orthodontics     Open Access  
Arab J. of Interventional Radiology     Open Access  
Archives of Cardiovascular Imaging     Open Access   (Followers: 2, SJR: 0.187, CiteScore: 0)
Archives of Intl. Surgery     Open Access   (Followers: 10, SJR: 0.302, CiteScore: 1)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Archives of Medicine and Surgery     Open Access  
Archives of Pharmacy Practice     Open Access   (Followers: 8, SJR: 0.102, CiteScore: 0)
Archives of Trauma Research     Open Access   (Followers: 3, SJR: 0.37, CiteScore: 2)
Asia Pacific J. of Clinical Trials : Nervous System Diseases     Open Access  
Asia-Pacific J. of Oncology Nursing     Open Access   (Followers: 5)
Asian J. of Andrology     Open Access   (Followers: 1, SJR: 0.856, CiteScore: 2)
Asian J. of Neurosurgery     Open Access   (Followers: 2)
Asian J. of Oncology     Open Access   (Followers: 2)
Asian J. of Transfusion Science     Open Access   (Followers: 1, SJR: 0.35, CiteScore: 1)
Asian Pacific J. of Reproduction     Open Access   (SJR: 0.227, CiteScore: 1)
Asian Pacific J. of Tropical Biomedicine     Open Access   (Followers: 2, SJR: 0.491, CiteScore: 2)
Asian Pacific J. of Tropical Medicine     Open Access   (Followers: 1, SJR: 0.561, CiteScore: 2)
Astrocyte     Open Access  
Avicenna J. of Medicine     Open Access   (Followers: 1)
AYU : An international quarterly journal of research in Ayurveda     Open Access   (Followers: 6)
Benha Medical J.     Open Access  
Biomedical and Biotechnology Research J.     Open Access  
BLDE University J. of Health Sciences     Open Access  
Brain Circulation     Open Access   (Followers: 1)
Bulletin of Faculty of Physical Therapy     Open Access   (Followers: 1)
Canadian J. of Rural Medicine     Full-text available via subscription   (SJR: 0.202, CiteScore: 0)
Cancer Translational Medicine     Open Access   (Followers: 2)
Cardiology Plus     Open Access  
Chinese Medical J.     Open Access   (Followers: 10, SJR: 0.52, CiteScore: 1)
CHRISMED J. of Health and Research     Open Access   (Followers: 2)
Clinical Cancer Investigation J.     Open Access  
Clinical Dermatology Review     Open Access   (Followers: 4)
Clinical Trials in Degenerative Diseases     Open Access  
Clinical Trials in Orthopedic Disorders     Open Access  
Community Acquired Infection     Open Access  
Conservation and Society     Open Access   (Followers: 10, SJR: 0.811, CiteScore: 2)
Contemporary Clinical Dentistry     Open Access   (Followers: 4, SJR: 0.353, CiteScore: 1)
Current Medical Issues     Open Access   (Followers: 1)
CytoJ.     Open Access   (Followers: 2, SJR: 0.543, CiteScore: 1)
Delta J. of Ophthalmology     Open Access  
Dental Hypotheses     Open Access   (Followers: 4, SJR: 0.152, CiteScore: 0)
Dental Research J.     Open Access   (Followers: 12, SJR: 0.416, CiteScore: 1)
Dentistry and Medical Research     Open Access  
Digital Medicine     Open Access  
Drug Development and Therapeutics     Open Access  
Education for Health     Open Access   (Followers: 6, SJR: 0.242, CiteScore: 0)
Egyptian J. of Bronchology     Open Access  
Egyptian J. of Cardiothoracic Anesthesia     Open Access  
Egyptian J. of Cataract and Refractive Surgery     Open Access   (Followers: 1, SJR: 1.799, CiteScore: 2)
Egyptian J. of Chest Diseases and Tuberculosis     Open Access   (Followers: 3, SJR: 0.155, CiteScore: 0)
Egyptian J. of Dermatology and Venerology     Open Access   (Followers: 1)
Egyptian J. of Haematology     Open Access   (Followers: 1)
Egyptian J. of Internal Medicine     Open Access   (Followers: 1)
Egyptian J. of Obesity, Diabetes and Endocrinology     Open Access   (Followers: 1)
Egyptian J. of Otolaryngology     Open Access   (Followers: 2)
Egyptian J. of Psychiatry     Open Access   (Followers: 2)
Egyptian J. of Surgery     Open Access   (Followers: 1)
Egyptian Nursing J.     Open Access  
Egyptian Orthopaedic J.     Open Access   (Followers: 2)
Egyptian Pharmaceutical J.     Open Access  
Egyptian Retina J.     Open Access  
Egyptian Rheumatology and Rehabilitation     Open Access   (Followers: 1)
Endodontology     Open Access  
Endoscopic Ultrasound     Open Access   (Followers: 1, SJR: 0.822, CiteScore: 2)
Environmental Disease     Open Access   (Followers: 3)
Eurasian J. of Pulmonology     Open Access  
European J. of Dentistry     Open Access   (Followers: 2, SJR: 0.749, CiteScore: 2)
European J. of General Dentistry     Open Access   (Followers: 1, SJR: 0.12, CiteScore: 0)
European J. of Prosthodontics     Open Access   (Followers: 3)
European J. of Psychology and Educational Studies     Open Access   (Followers: 11, SJR: 0.113, CiteScore: 0)
Fertility Science and Research     Open Access  
Formosan J. of Surgery     Open Access   (SJR: 0.112, CiteScore: 0)
Genome Integrity     Open Access   (Followers: 2, SJR: 0.153, CiteScore: 0)
Glioma     Open Access  
Global J. of Transfusion Medicine     Open Access   (Followers: 1)
Gynecology and Minimally Invasive Therapy     Open Access   (SJR: 0.311, CiteScore: 1)
Hamdan Medical J.     Open Access  
Heart and Mind     Open Access  
Heart India     Open Access   (Followers: 1)
Heart Views     Open Access   (Followers: 2)
Hepatitis B Annual     Open Access   (Followers: 3)
Ibnosina J. of Medicine and Biomedical Sciences     Open Access  
IJS Short Reports     Open Access  
Imam J. of Applied Sciences     Open Access  
Indian Dermatology Online J.     Open Access   (Followers: 3)
Indian J. of Allergy, Asthma and Immunology     Open Access   (Followers: 1)
Indian J. of Anaesthesia     Open Access   (Followers: 7, SJR: 0.478, CiteScore: 1)
Indian J. of Burns     Open Access   (Followers: 1)
Indian J. of Cancer     Open Access   (Followers: 1, SJR: 0.361, CiteScore: 1)
Indian J. of Cerebral Palsy     Open Access   (Followers: 1)
Indian J. of Community Medicine     Open Access   (Followers: 2, SJR: 0.37, CiteScore: 1)
Indian J. of Critical Care Medicine     Open Access   (Followers: 4, SJR: 0.604, CiteScore: 1)
Indian J. of Dental Research     Open Access   (Followers: 5, SJR: 0.266, CiteScore: 1)
Indian J. of Dental Sciences     Open Access  
Indian J. of Dentistry     Open Access   (Followers: 1)
Indian J. of Dermatology     Open Access   (Followers: 2, SJR: 0.468, CiteScore: 1)
Indian J. of Dermatology, Venereology and Leprology     Open Access   (Followers: 4, SJR: 0.445, CiteScore: 1)
Indian J. of Dermatopathology and Diagnostic Dermatology     Open Access  
Indian J. of Drugs in Dermatology     Open Access   (Followers: 1, SJR: 0.791, CiteScore: 1)
Indian J. of Endocrinology and Metabolism     Open Access   (Followers: 4, SJR: 0.568, CiteScore: 1)
Indian J. of Health Sciences and Biomedical Research KLEU     Open Access   (Followers: 2)
Indian J. of Medical and Paediatric Oncology     Open Access   (SJR: 0.425, CiteScore: 1)
Indian J. of Medical Microbiology     Open Access   (Followers: 2, SJR: 0.503, CiteScore: 1)
Indian J. of Medical Research     Open Access   (Followers: 4, SJR: 0.656, CiteScore: 1)
Indian J. of Medical Sciences     Open Access   (Followers: 2, SJR: 0.102, CiteScore: 0)
Indian J. of Multidisciplinary Dentistry     Open Access   (Followers: 1)
Indian J. of Nephrology     Open Access   (Followers: 2, SJR: 0.347, CiteScore: 1)
Indian J. of Nuclear Medicine     Open Access   (Followers: 2, SJR: 0.23, CiteScore: 0)
Indian J. of Occupational and Environmental Medicine     Open Access   (Followers: 3, SJR: 0.225, CiteScore: 1)
Indian J. of Ophthalmology     Open Access   (Followers: 4, SJR: 0.498, CiteScore: 1)
Indian J. of Oral Health and Research     Open Access  
Indian J. of Oral Sciences     Open Access   (Followers: 1)
Indian J. of Orthopaedics     Open Access   (Followers: 8, SJR: 0.392, CiteScore: 1)
Indian J. of Otology     Open Access   (Followers: 1, SJR: 0.199, CiteScore: 0)
Indian J. of Paediatric Dermatology     Open Access   (Followers: 2)
Indian J. of Pain     Open Access   (Followers: 1)
Indian J. of Palliative Care     Open Access   (Followers: 6, SJR: 0.454, CiteScore: 1)
Indian J. of Pathology and Microbiology     Open Access   (Followers: 2, SJR: 0.276, CiteScore: 1)
Indian J. of Pharmacology     Open Access   (SJR: 0.412, CiteScore: 1)
Indian J. of Plastic Surgery     Open Access   (Followers: 12, SJR: 0.311, CiteScore: 0)
Indian J. of Psychiatry     Open Access   (Followers: 3, SJR: 0.408, CiteScore: 1)
Indian J. of Psychological Medicine     Open Access   (SJR: 0.368, CiteScore: 1)
Indian J. of Public Health     Open Access   (Followers: 1)
Indian J. of Radiology and Imaging     Open Access   (Followers: 4)
Indian J. of Research in Homoeopathy     Open Access  
Indian J. of Respiratory Care     Open Access  
Indian J. of Rheumatology     Open Access   (SJR: 0.119, CiteScore: 0)
Indian J. of Sexually Transmitted Diseases and AIDS     Open Access   (Followers: 2, SJR: 0.34, CiteScore: 0)
Indian J. of Social Psychiatry     Open Access   (Followers: 2)
Indian J. of Transplantation     Open Access  
Indian J. of Urology     Open Access   (Followers: 3, SJR: 0.434, CiteScore: 1)
Indian J. of Vascular and Endovascular Surgery     Open Access   (Followers: 2)
Indian Spine J.     Open Access  
Industrial Psychiatry J.     Open Access   (Followers: 2)
Intervention     Open Access   (Followers: 1)
Intl. Archives of Health Sciences     Open Access  
Intl. J. of Abdominal Wall and Hernia Surgery     Open Access   (Followers: 1)
Intl. J. of Academic Medicine     Open Access  
Intl. J. of Advanced Medical and Health Research     Open Access  
Intl. J. of Applied and Basic Medical Research     Open Access  
Intl. J. of Clinical and Experimental Physiology     Open Access   (Followers: 1)
Intl. J. of Clinicopathological Correlation     Open Access   (Followers: 1)
Intl. J. of Community Dentistry     Open Access  
Intl. J. of Critical Illness and Injury Science     Open Access   (Followers: 1, SJR: 0.192, CiteScore: 0)
Intl. J. of Educational and Psychological Researches     Open Access   (Followers: 4)
Intl. J. of Environmental Health Engineering     Open Access   (Followers: 1)
Intl. J. of Forensic Odontology     Open Access   (Followers: 1)
Intl. J. of Green Pharmacy     Open Access   (Followers: 3, SJR: 0.142, CiteScore: 0)
Intl. J. of Growth Factors and Stem Cells in Dentistry     Open Access  
Intl. J. of Health & Allied Sciences     Open Access   (Followers: 3)
Intl. J. of Health System and Disaster Management     Open Access   (Followers: 3)
Intl. J. of Heart Rhythm     Open Access  
Intl. J. of Medicine and Public Health     Open Access   (Followers: 6)
Intl. J. of Mycobacteriology     Open Access   (SJR: 0.535, CiteScore: 1)
Intl. J. of Noncommunicable Diseases     Open Access  
Intl. J. of Nutrition, Pharmacology, Neurological Diseases     Open Access   (Followers: 4, SJR: 0.17, CiteScore: 0)
Intl. J. of Oral Health Sciences     Open Access   (Followers: 2)
Intl. J. of Orofacial Biology     Open Access   (Followers: 1)
Intl. J. of Orofacial Research     Open Access   (Followers: 1)
Intl. J. of Orthodontic Rehabilitation     Open Access   (Followers: 1)
Intl. J. of Pedodontic Rehabilitation     Open Access  
Intl. J. of Pharmaceutical Investigation     Open Access   (Followers: 1)
Intl. J. of Preventive Medicine     Open Access   (Followers: 1, SJR: 0.623, CiteScore: 1)
Intl. J. of Shoulder Surgery     Open Access   (Followers: 5, SJR: 0.653, CiteScore: 1)
Intl. J. of the Cardiovascular Academy     Open Access   (SJR: 0.105, CiteScore: 0)
Intl. J. of Trichology     Open Access   (SJR: 0.4, CiteScore: 1)
Intl. J. of Yoga     Open Access   (Followers: 15)
Intl. J. of Yoga : Philosophy, Psychology and Parapsychology     Open Access   (Followers: 6)
Iranian J. of Nursing and Midwifery Research     Open Access   (Followers: 3)
Iraqi J. of Hematology     Open Access  

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Journal Cover
Indian Journal of Medical Research
Journal Prestige (SJR): 0.656
Citation Impact (citeScore): 1
Number of Followers: 4  

  This is an Open Access Journal Open Access journal
ISSN (Print) 0971-5916
Published by Medknow Publishers Homepage  [427 journals]
  • HIV prevention & treatment strategies - Current challenges &
           future prospects

    • Authors: Jayanta Bhattacharya
      Pages: 671 - 674
      Abstract: Jayanta Bhattacharya
      Indian Journal of Medical Research 2018 148(6):671-674

      Citation: Indian Journal of Medical Research 2018 148(6):671-674
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/0971-5916.252150
      Issue No: Vol. 148, No. 6 (2019)
       
  • How should one tackle prediabetes in India?

    • Authors: Jacob Jose, Nihal Thomas
      Pages: 675 - 676
      Abstract: Jacob Jose, Nihal Thomas
      Indian Journal of Medical Research 2018 148(6):675-676

      Citation: Indian Journal of Medical Research 2018 148(6):675-676
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/ijmr.IJMR_1785_18
      Issue No: Vol. 148, No. 6 (2019)
       
  • Statistical fallacies & errors can also jeopardize life & health
           of many

    • Authors: Abhaya Indrayan
      Pages: 677 - 679
      Abstract: Abhaya Indrayan
      Indian Journal of Medical Research 2018 148(6):677-679

      Citation: Indian Journal of Medical Research 2018 148(6):677-679
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/ijmr.IJMR_853_18
      Issue No: Vol. 148, No. 6 (2019)
       
  • Carcinogenicity of smokeless tobacco: Evidence from studies in humans
           & experimental animals

    • Authors: Saman Warnakulasuriya, Kurt Straif
      Pages: 681 - 686
      Abstract: Saman Warnakulasuriya, Kurt Straif
      Indian Journal of Medical Research 2018 148(6):681-686
      A Working Group of the Monographs programme of the International Agency for Research on Cancer has classified smokeless tobacco as carcinogenic to humans (Group 1). This review article summarizes the data that support the evaluations of sufficient evidence in humans and in experimental animals for the carcinogenicity of smokeless tobacco whether used alone or with betel quid. It also identifies compounds of smokeless tobacco relevant to carcinogenicity (prominently tobacco-specific nitrosamines) and addiction (nicotine). The epidemiological evidence is summarized for oral cancer, other cancers associated with smokeless tobacco and oral potentially malignant lesions with a focus on analytical studies from the SEARO Region. Studies on cancer in experimental animals are summarized with a focus on studies applying smokeless tobacco products typical for the regions, such as mishri and naswar.
      Citation: Indian Journal of Medical Research 2018 148(6):681-686
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/ijmr.IJMR_149_18
      Issue No: Vol. 148, No. 6 (2019)
       
  • Cervical cancer screening in rural India: Status & current concepts

    • Authors: Anand Narain Srivastava, Jata Shankar Misra, Shruti Srivastava, Bhudav C Das, Shilpi Gupta
      Pages: 687 - 696
      Abstract: Anand Narain Srivastava, Jata Shankar Misra, Shruti Srivastava, Bhudav C Das, Shilpi Gupta
      Indian Journal of Medical Research 2018 148(6):687-696
      Cervical carcinoma is one of the most common and dreaded diseases of women, and in India, it accounts for 16 per cent of total cervical cancer cases occurring globally. The situation is more alarming in the rural areas where the majority of women are illiterate and ignorant about the hazards of cervical cancer. Different screening strategies such as rural cancer registries and camp approach for cancer detection have been found useful in minimizing the problem of cervical cancer in the villages. Various screening techniques such as visual inspection with acetic acid, visual inspection with Lugol's iodine, visual inspection with magnification devices-magnavisualizer, Pap smear and HPV-DNA testing have been suggested and tried under low-resource settings of our country, and cervical cytology screening has been found effective in reducing incidence of the disease. In the present review, feasibility of different screening methods has been assessed to find out the most suitable mode applicable at the rural level. Single lifetime screening particularly of high-risk women along with analysis of cost-effective tumour markers such as Argyrophilic nucleolar organizer regions (AgNOR) counts to discriminate high-risk dysplasia cases appears to be an appropriate approach in fighting against cervical cancer.
      Citation: Indian Journal of Medical Research 2018 148(6):687-696
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/ijmr.IJMR_5_17
      Issue No: Vol. 148, No. 6 (2019)
       
  • Nutrition-pollution interaction: An emerging research area

    • Authors: Dinesh Kumar Bharatraj, Srinivasa Reddy Yathapu
      Pages: 697 - 704
      Abstract: Dinesh Kumar Bharatraj, Srinivasa Reddy Yathapu
      Indian Journal of Medical Research 2018 148(6):697-704
      The impact of environmental pollution, especially chronic low exposures of heavy metals (Pb, Cd, Hg, As, Cr, etc.) on nutritional status and health of human and livestock, has become a cause of concern. It is established that malnutrition inhibits enzyme system, alters neurotransmitter levels, degenerate myelin, glial and neural elements, lowering of IQ scores as well as impairment of fine and gross motor coordination. Chronic low-level exposure to heavy metals also results in similar type of deformities at sub-clinical level. However, additive impact of undernutrition and adverse effects of heavy metal exposure is emerging as a serious threat to health in developing countries. High blood Pb/Cd levels and low nutrient levels cause subclinical damage of organ system such as haemopoietic, renal, nervous systems in neonates, children, post-partum women, and occupationally exposed population. This could be due to chronic low-level heavy metal exposures and vis-à-vis interaction between pollutants and nutrients. Our studies are focused on the utility of biomarkers for early subclinical detection of haemopoietic and rental toxicity. Lead exposure from non-conventional sources such as toys, pet/glass bottles, etc. suggest long-term investigation. The present review compiles result of studies conducted in this area highlighting the importance of pollution-nutrition interaction. This may facilitate policymakers on developing the strategies to counter the heavy metal exposure of humans/livestock and their consequences.
      Citation: Indian Journal of Medical Research 2018 148(6):697-704
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/ijmr.IJMR_1733_18
      Issue No: Vol. 148, No. 6 (2019)
       
  • Effect of intensive lifestyle modification & metformin on cardiovascular
           risk in prediabetes: A pilot randomized control trial

    • Authors: Shruthi Kulkarni, Denis Xavier, Belinda George, Soumya Umesh, Saba Fathima, Ganapathi Bantwal
      Pages: 705 - 712
      Abstract: Shruthi Kulkarni, Denis Xavier, Belinda George, Soumya Umesh, Saba Fathima, Ganapathi Bantwal
      Indian Journal of Medical Research 2018 148(6):705-712
      Background & objectives: Prediabetes is associated with increased prevalence of cardiovascular disease (CVD). In participants with prediabetes, the effects of exercise and metformin were evaluated on high-sensitivity C-reactive protein (hsCRP) and carotid intima-media thickness (CIMT), surrogate markers of atherosclerosis and CVD compared with standard care.Methods: In a pilot randomized control trial, the participants were randomized in to three arms: standard care (STD), intensive lifestyle modification (ILSM) or ILSM and metformin (ILSM+Met) and followed up for six months. Monitoring of ILSM was done by a trained healthcare facilitator. hsCRP, CIMT and other relevant parameters were measured before and after intervention.Results: A total of 103 participants were randomized into three arms and followed up for six months. At six months, there was a reduction from baseline in weight and fasting blood sugar (FBS) (P <0.01) in all three arms and a reduction in haemoglobin A1c (P =0.03) only in the ILSM+Met arm. The differences in hsCRP over six months within the STD, ILSM and ILSM+Met arms were −0.12 (95% confidence interval, −1.81, 2.08), −0.58 (−2.64, 0.43) and −0.11 (−1.84, 1.56), respectively. There was no difference in hsCRP, CIMT (right) or CIMT (left) between the three arms at six months.Interpretation & conclusions: There was a reduction in weight and FBS from baseline in all three arms. There was, however, no difference seen in hsCRP and CIMT in the two intervention arms compared to standard care. Larger studies with long-term follow up need to be done to detect differences in risk markers for CVD in prediabetes.
      Citation: Indian Journal of Medical Research 2018 148(6):705-712
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/ijmr.IJMR_1201_17
      Issue No: Vol. 148, No. 6 (2019)
       
  • Molecular genotyping of clinically important blood group antigens in
           patients with thalassaemia

    • Authors: Swati Kulkarni, Bhavika Choudhary, Harita Gogri, Shashikant Patil, Mamta Manglani, Ratna Sharma, Manisha Madkaikar
      Pages: 713 - 720
      Abstract: Swati Kulkarni, Bhavika Choudhary, Harita Gogri, Shashikant Patil, Mamta Manglani, Ratna Sharma, Manisha Madkaikar
      Indian Journal of Medical Research 2018 148(6):713-720
      Background & objectives: In multitransfused thalassaemic patients, haemagglutination fails to phenotype the patient's blood group antigens due to the presence of donor-derived erythrocytes. DNA-based methods can overcome the limitations of haemagglutination and can be used to determine the correct antigen profile of these patients. This will facilitate the procurement of antigen-matched blood for transfusion to multitransfused patients. Thus, the aim of this study was to compare the serological phenotyping of common and clinically important antigens of Rh, Duffy, Kell, Kidd and MNS blood group systems with molecular genotyping amongst multitransfused thalassaemic patients.Methods: Blood samples from 200 patients with thalassaemia and 100 'O' group regular blood donors were tested using standard serological techniques and polymerase chain reaction-based methods for common antigens/alleles (C, c, D, E, e, Fya, Fyb, Jka, Jkb, K, k, M, N, S, s).Results: Genotyping and phenotyping results were discordant in 77 per cent of thalassaemic patients for five pairs of antithetical antigens of Rh, Duffy, Kell and Kidd blood group systems. In the MNS blood group system, 59.1 per cent of patients showed discrepancy. The rate of alloimmunization among thalassaemics was 7.5 per cent.Interpretation & conclusions: Molecular genotyping enabled the determination of the actual antigen profile in multitransfused thalassaemia patients. This would help reduce the problem of alloimmunization in such patients and would also aid in the better management of transfusion therapy.
      Citation: Indian Journal of Medical Research 2018 148(6):713-720
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/ijmr.IJMR_455_17
      Issue No: Vol. 148, No. 6 (2019)
       
  • Frequency & predictors of pancreatitis in symptomatic primary
           hyperparathyroidism

    • Authors: Ashutosh Kumar Arya, Sanjay Kumar Bhadada, Soham Mukherjee, Priyanka Singh, Surinder S Rana, Divya Dahiya, Ashwani Sood, Uma Nahar Saikia, Mahesh Prakash, Deepak Kumar Bhasin, Arunanshu Behera, Rama Walia, Anil Bhansali
      Pages: 721 - 727
      Abstract: Ashutosh Kumar Arya, Sanjay Kumar Bhadada, Soham Mukherjee, Priyanka Singh, Surinder S Rana, Divya Dahiya, Ashwani Sood, Uma Nahar Saikia, Mahesh Prakash, Deepak Kumar Bhasin, Arunanshu Behera, Rama Walia, Anil Bhansali
      Indian Journal of Medical Research 2018 148(6):721-727
      Background & objectives: The frequency and predictors of pancreatitis in primary hyperparathyroidism (PHPT) are not well understood. The objective of the present study was to evaluate the frequency of pancreatitis in patients with PHPT and its association with clinical and biochemical parameters of the disease.Methods: In this retrospective study all consecutive patients with PHPT registered in the PHPT registry (www.indianphptregistry.com) from the year 2004 to 2013 were included. The clinical, biochemical and radiological parameters related to pancreatitis were evaluated in histologically proven PHPT patients.Results: A total of 218 patients (63 men; mean age: 40.6±14.4 yr) underwent surgery for PHPT during the study. Pancreatitis occurred in 35 [16%, 18 acute and 17 chronic pancreatitis (CP)] patients and male:female ratio was 1:0.94. Skeletal manifestations were seen less frequently in PHPT with pancreatitis as compared to that of PHPT without pancreatitis. PHPT with pancreatitis had significantly higher serum calcium (12.4±2.0 vs. 11.7±1.5 mg/dl, P <0.05) in comparison to PHPT without pancreatitis. PHPT with acute pancreatitis (AP) had higher serum calcium (P <0.05) and parathyroid hormone (PTH) (P <0.05) levels than PHPT with CP. Curative parathyroidectomy improved the symptoms associated with pancreatitis as there was no recurrence in AP group, whereas recurrence was observed only in about 10 per cent patients of the CP group.Interpretation & conclusions: Pancreatitis was observed in 16 per cent of PHPT patients with male predominance in the study population. No recurrence of AP was observed after curative surgery. It may be proposed that serum amylase with calcium and PTH should be measured in all patients of PHPT with pain abdomen to rule out pancreatitis.
      Citation: Indian Journal of Medical Research 2018 148(6):721-727
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/ijmr.IJMR_353_16
      Issue No: Vol. 148, No. 6 (2019)
       
  • Clinical significance of galectin-3 expression in malformed hepatic venous
           tissue

    • Authors: Junbo Qiao, Yongwei Chen, Changxian Dong, Jin Li
      Pages: 728 - 733
      Abstract: Junbo Qiao, Yongwei Chen, Changxian Dong, Jin Li
      Indian Journal of Medical Research 2018 148(6):728-733
      Background & objectives: Hepatic venous malformation gradually develops over time and exhibits the malignant biological behaviours of being locally invasive, causing morphological and functional damage to local tissue, and may even cause systemic coagulopathy. Studies show that galectin-3(Gal-3) expression is closely associated with local invasion of malignant tumours. In this study an attempt was made to assess the clinical significance of Gal-3 in local invasion during hepatic venous malformation in patients.Methods: Gal-3 protein and its mRNA expression were examined using immunohistochemistry and in situ hybridization in a total of 126 patients with hepatic venous malformation. For control tissue, 20 cases of normal tissue distal to surgical margins were also examined. In addition, the association between Gal-3 expression and pathological parameters was analyzed in hepatic venous malformation patients.Results: Gal-3 mRNA positivity was observed in 65.08 per cent (82/126) of hepatic venous malformation tissue samples, which was higher than the rate of 20 per cent (4/20) (P <0.05) seen in control tissues. Gal-3 protein positivity was observed in 58.73 per cent (74/126) of hepatic venous malformation tissue samples, which was higher than the rate of 15 per cent (3/20) (P <0.05) seen in the normal tissue. Gal-3 expression was not significantly associated with age or gender. However, there was a significant association between Gal-3 positivity and lesion size, local invasion depth, and involvement with the hepatic vein and the portal system.Interpretation & conclusions: Local tissue invasion and destruction by hepatic venous malformation may be related to the upregulation of Gal-3. Gal-3 expression and the development of venous malformation may be related and needs to be studied further.
      Citation: Indian Journal of Medical Research 2018 148(6):728-733
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/ijmr.IJMR_500_17
      Issue No: Vol. 148, No. 6 (2019)
       
  • Estimation of plasma levels of bisphenol-A & phthalates in fertile &
           infertile women by gas chromatography-mass spectrometry

    • Authors: Prajakta Parag Pednekar, Rahul Krishnaji Gajbhiye, Anushree D Patil, Suchitra Vishwambhar Surve, Ajit Ganesh Datar, Geetha Dharmesh Balsarkar, Anahita R Chuahan, Geeta Ramesh Vanage
      Pages: 734 - 742
      Abstract: Prajakta Parag Pednekar, Rahul Krishnaji Gajbhiye, Anushree D Patil, Suchitra Vishwambhar Surve, Ajit Ganesh Datar, Geetha Dharmesh Balsarkar, Anahita R Chuahan, Geeta Ramesh Vanage
      Indian Journal of Medical Research 2018 148(6):734-742
      Background & objectives: Bisphenol-A (BPA) and phthalates are utilized widely in consumer products. Due to their ubiquitous presence in the environment, a concern is expressed worldwide about their possible effect on human reproductive health. This study was conducted to compare the internal exposure of BPA and phthalates (using their metabolites as biomarkers) in plasma samples of infertile and fertile women.Methods: A sensitive gas chromatographic-mass spectrometric (GC-MS) method was developed to simultaneously quantify BPA and four phthalate monoester metabolites [namely mono-methyl phthalate (MMP), mono-benzyl phthalate (MBzP), mono-2-ethylhexyl phthalate (MEHP) and mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP)] in human plasma. The method was validated using charcoal-stripped human plasma. Activated charcoal was also utilized to reduce contamination from reagents. The method was designed to account for and/or eliminate background contamination from all sources.Results: The limit of quantification for the method was 5 ng/ml for MMP and MBzP, while 1 ng/ml for BPA, MEHP and MEHHP, respectively. The precision and accuracy were well within the acceptable range. BPA was detectable in 77 per cent of plasma samples of infertile women and 29 per cent of fertile women. All the four phthalate metabolites were detected in plasma samples of both fertile and infertile women.Interpretation & conclusions: A GC-MS was developed and validated to estimate the BPA and four phthalate monoester metabolites in human plasma. It was utilised to analyse the plasma samples from fertile and infertile women. The infertile women showed significantly higher plasma concentrations of MBzP, BPA and MEHHP as compared to fertile women. The levels of MMP and MEHP were not significantly different between the two groups. Further studies need to be done to confirm these preliminary findings.
      Citation: Indian Journal of Medical Research 2018 148(6):734-742
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/ijmr.IJMR_2077_16
      Issue No: Vol. 148, No. 6 (2019)
       
  • Effect of anti-inflammatory activity of ranolazine in rat model of
           inflammation

    • Authors: R Naveena, Nayana K Hashilkar, Reshma Davangeri, Suneel I Majagi
      Pages: 743 - 747
      Abstract: R Naveena, Nayana K Hashilkar, Reshma Davangeri, Suneel I Majagi
      Indian Journal of Medical Research 2018 148(6):743-747
      Background & objectives: Inflammatory processes are a recognized feature of atherosclerotic lesions. Ranolazine inhibits the inflammatory markers such as C-reactive protein, interleukins-1 and -6 and tumour necrosis factor-alpha. The present study was planned to evaluate the effect of anti-inflammatory activity of ranolazine in acute and sub-acute models of inflammation in rats and compare the same with that of control (gum acacia 1%) and aspirin (standard anti-inflammatory drug).Methods: Adult male Wistar rats (150-180 g) were used for the study. They were divided into three groups (n=6). One per cent gum acacia (control), aspirin (200 mg/kg body weight) and ranolazine (180 mg/kg body weight) were given orally. Acute inflammation was induced by injecting carrageenan in the left hind paw. Paw oedema volume and percentage inhibition were measured. Subacute inflammation was induced by implanting foreign bodies subcutaneously. Percentage inhibition of granuloma dry weight and haematoxylin and eosin stained sections of granulation tissue were studied.Results: In acute and subacute model study, ranolazine significantly (P <0.01) decreased the paw oedema volume and granuloma dry weight as compared to control and it was comparable to that of aspirin and histopathological sections showed a decrease in granulation tissue formation as compared to control.Interpretation & conclusions: Ranolazine demonstrated significant anti-inflammatory activity in acute and subacute models of inflammation and needs further evaluation for its use in reducing atherosclerosis.
      Citation: Indian Journal of Medical Research 2018 148(6):743-747
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/ijmr.IJMR_1504_16
      Issue No: Vol. 148, No. 6 (2019)
       
  • A four year experience in narcolepsy from a sleep clinic at a tertiary
           care centre with a short review of contemporary Indian literature

    • Authors: Animesh Ray, Kewal Kanabar, Vishwanath Upadhyay, Surendra Kumar Sharma
      Pages: 748 - 751
      Abstract: Animesh Ray, Kewal Kanabar, Vishwanath Upadhyay, Surendra Kumar Sharma
      Indian Journal of Medical Research 2018 148(6):748-751
      Narcolepsy is a common sleep disorder in Western countries but rarely reported from India. Here, we report a small case series of four narcolepsy patients seen over a four year period in the sleep clinic of a tertiary care hospital in north India. The diagnosis was established by clinical history and two or more sleep-onset rapid eye movements (SOREMs) on multiple sleep latency tests (MSLTs) following overnight polysomnography (PSG). The mean age of patients was 26.2±6.4 yr; one patient had associated cataplexy and another one had all four cardinal symptoms of narcolepsy. All these patients had a history of excessive daytime sleepiness (EDS). The mean body mass index was 24.2±4.7 kg/m[2]. The mean sleep latency during MSLT was 2.7±1.3 min, and the mean REM latency was 5.7±2.9 min. Narcolepsy, although rarely reported from India, should be suspected in young non-obese patients complaining of EDS and confirmed by performing MSLT following overnight PSG.
      Citation: Indian Journal of Medical Research 2018 148(6):748-751
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/ijmr.IJMR_888_16
      Issue No: Vol. 148, No. 6 (2019)
       
  • A cross-sectional study on pre-hypertension & its association with
           anthropometric indices among undergraduate medical students in Andhra
           Pradesh, India

    • Authors: P Likhita Bhavani, Sandhya Gupta, Sharmilakrishna Thanikonda, Venkatarao Epari
      Pages: 752 - 755
      Abstract: P Likhita Bhavani, Sandhya Gupta, Sharmilakrishna Thanikonda, Venkatarao Epari
      Indian Journal of Medical Research 2018 148(6):752-755

      Citation: Indian Journal of Medical Research 2018 148(6):752-755
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/ijmr.IJMR_678_17
      Issue No: Vol. 148, No. 6 (2019)
       
  • Molecular characterization of chikungunya virus from urbanized villages of
           Pune, Maharashtra, India, 2016

    • Authors: Gururaj Rao Deshpande, Bipin Tilekar, Supriya L Hundekar, Kirtee Khutwad, Rashmi S Gunjikar, Shankar Vidhate, Gajanan N Sapkal
      Pages: 756 - 758
      Abstract: Gururaj Rao Deshpande, Bipin Tilekar, Supriya L Hundekar, Kirtee Khutwad, Rashmi S Gunjikar, Shankar Vidhate, Gajanan N Sapkal
      Indian Journal of Medical Research 2018 148(6):756-758

      Citation: Indian Journal of Medical Research 2018 148(6):756-758
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/ijmr.IJMR_558_17
      Issue No: Vol. 148, No. 6 (2019)
       
  • Emphysematous pyelonephritis: Diagnostic pearls in imaging

    • Authors: Anirudh V Nair, PV Ramachandran
      Pages: 759 - 760
      Abstract: Anirudh V Nair, PV Ramachandran
      Indian Journal of Medical Research 2018 148(6):759-760

      Citation: Indian Journal of Medical Research 2018 148(6):759-760
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/ijmr.IJMR_114_17
      Issue No: Vol. 148, No. 6 (2019)
       
  • Comb sign in a patient with ankylosing spondylitis

    • Authors: Yu-Hisu Chen, Hsiang-Cheng Chen
      Pages: 761 - 762
      Abstract: Yu-Hisu Chen, Hsiang-Cheng Chen
      Indian Journal of Medical Research 2018 148(6):761-762

      Citation: Indian Journal of Medical Research 2018 148(6):761-762
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/ijmr.IJMR_1256_17
      Issue No: Vol. 148, No. 6 (2019)
       
  • Presenting medical statistics from proposal to publication

    • Authors: P. S. S. Sundar Rao
      Pages: 763 - 764
      Abstract: P. S. S. Sundar Rao
      Indian Journal of Medical Research 2018 148(6):763-764

      Citation: Indian Journal of Medical Research 2018 148(6):763-764
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/0971-5916.252167
      Issue No: Vol. 148, No. 6 (2019)
       
  • Essentials of dermatology and sexually transmitted diseases: An
           illustrated synopsis

    • Authors: Arun C Inamadar
      Pages: 764 - 765
      Abstract: Arun C Inamadar
      Indian Journal of Medical Research 2018 148(6):764-765

      Citation: Indian Journal of Medical Research 2018 148(6):764-765
      PubDate: Tue,12 Feb 2019
      DOI: 10.4103/ijmr.IJMR_1960_18
      Issue No: Vol. 148, No. 6 (2019)
       
  • Panel of Reviewers (2018)

    • Pages: 766 - 784
      Abstract:
      Indian Journal of Medical Research 2018 148(6):766-784

      Citation: Indian Journal of Medical Research 2018 148(6):766-784
      PubDate: Tue,12 Feb 2019
      Issue No: Vol. 148, No. 6 (2019)
       
 
 
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