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Publisher: Medknow Publishers   (Total: 426 journals)

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Showing 1 - 200 of 426 Journals sorted alphabetically
Acta Medica Intl.     Open Access   (SJR: 0.101, CiteScore: 0)
Advanced Arab Academy of Audio-Vestibulogy J.     Open Access  
Advanced Biomedical Research     Open Access  
Advances in Human Biology     Open Access   (Followers: 4)
Advances in Skeletal Muscle Function Assessment     Open Access  
African J. for Infertility and Assisted Conception     Open Access  
African J. of Medical and Health Sciences     Open Access   (Followers: 3)
African J. of Paediatric Surgery     Open Access   (Followers: 7, SJR: 0.25, CiteScore: 1)
African J. of Trauma     Open Access   (Followers: 1)
Ain-Shams J. of Anaesthesiology     Open Access   (Followers: 3)
Al-Azhar Assiut Medical J.     Open Access   (Followers: 2)
Al-Basar Intl. J. of Ophthalmology     Open Access   (Followers: 1)
Alexandria J. of Pediatrics     Open Access   (Followers: 1)
Ancient Science of Life     Open Access   (Followers: 5)
Anesthesia : Essays and Researches     Open Access   (Followers: 10)
Annals of African Medicine     Open Access   (Followers: 2, SJR: 0.258, CiteScore: 1)
Annals of Bioanthropology     Open Access   (Followers: 4)
Annals of Cardiac Anaesthesia     Open Access   (Followers: 14, SJR: 0.308, CiteScore: 1)
Annals of Indian Academy of Neurology     Open Access   (Followers: 3, SJR: 0.434, CiteScore: 1)
Annals of Indian Academy of Otorhinolaryngology Head and Neck Surgery     Open Access  
Annals of Indian Psychiatry     Open Access  
Annals of Maxillofacial Surgery     Open Access   (Followers: 6)
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 12, SJR: 0.352, CiteScore: 1)
Annals of Saudi Medicine     Open Access   (SJR: 0.238, CiteScore: 1)
Annals of Thoracic Medicine     Open Access   (Followers: 6, SJR: 0.524, CiteScore: 1)
Annals of Tropical Medicine and Public Health     Open Access   (Followers: 13, SJR: 0.152, CiteScore: 0)
Annals of Tropical Pathology     Open Access  
Apollo Medicine     Open Access  
APOS Trends in Orthodontics     Open Access   (Followers: 1)
Arab J. of Interventional Radiology     Open Access   (Followers: 1)
Archives of Cardiovascular Imaging     Open Access   (Followers: 2, SJR: 0.187, CiteScore: 0)
Archives of Intl. Surgery     Open Access   (Followers: 10, SJR: 0.302, CiteScore: 1)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Archives of Medicine and Surgery     Open Access  
Archives of Pharmacy Practice     Open Access   (Followers: 10, SJR: 0.102, CiteScore: 0)
Archives of Trauma Research     Open Access   (Followers: 3, SJR: 0.37, CiteScore: 2)
Asia Pacific J. of Clinical Trials : Nervous System Diseases     Open Access  
Asia-Pacific J. of Oncology Nursing     Open Access   (Followers: 5)
Asian J. of Andrology     Open Access   (Followers: 1, SJR: 0.856, CiteScore: 2)
Asian J. of Neurosurgery     Open Access   (Followers: 2)
Asian J. of Oncology     Open Access   (Followers: 2)
Asian J. of Transfusion Science     Open Access   (Followers: 1, SJR: 0.35, CiteScore: 1)
Asian Pacific J. of Reproduction     Open Access   (SJR: 0.227, CiteScore: 1)
Asian Pacific J. of Tropical Biomedicine     Open Access   (Followers: 2, SJR: 0.491, CiteScore: 2)
Asian Pacific J. of Tropical Medicine     Open Access   (Followers: 1, SJR: 0.561, CiteScore: 2)
Astrocyte     Open Access  
Avicenna J. of Medicine     Open Access   (Followers: 1)
AYU : An international quarterly journal of research in Ayurveda     Open Access   (Followers: 6)
Benha Medical J.     Open Access  
Biomedical and Biotechnology Research J.     Open Access  
BLDE University J. of Health Sciences     Open Access  
Brain Circulation     Open Access   (Followers: 1)
Bulletin of Faculty of Physical Therapy     Open Access   (Followers: 1)
Canadian J. of Rural Medicine     Full-text available via subscription   (SJR: 0.202, CiteScore: 0)
Cancer Translational Medicine     Open Access   (Followers: 2)
Cardiology Plus     Open Access   (Followers: 1)
Chinese Medical J.     Open Access   (Followers: 10, SJR: 0.52, CiteScore: 1)
CHRISMED J. of Health and Research     Open Access   (Followers: 2)
Clinical Cancer Investigation J.     Open Access  
Clinical Dermatology Review     Open Access   (Followers: 4)
Clinical Trials in Degenerative Diseases     Open Access  
Clinical Trials in Orthopedic Disorders     Open Access  
Community Acquired Infection     Open Access  
Conservation and Society     Open Access   (Followers: 8, SJR: 0.811, CiteScore: 2)
Contemporary Clinical Dentistry     Open Access   (Followers: 4, SJR: 0.353, CiteScore: 1)
Current Medical Issues     Open Access   (Followers: 1)
CytoJ.     Open Access   (Followers: 2, SJR: 0.543, CiteScore: 1)
Delta J. of Ophthalmology     Open Access  
Dental Hypotheses     Open Access   (Followers: 4, SJR: 0.152, CiteScore: 0)
Dental Research J.     Open Access   (Followers: 13, SJR: 0.416, CiteScore: 1)
Dentistry and Medical Research     Open Access  
Digital Medicine     Open Access  
Drug Development and Therapeutics     Open Access  
Education for Health     Open Access   (Followers: 6, SJR: 0.242, CiteScore: 0)
Egyptian J. of Bronchology     Open Access  
Egyptian J. of Cardiothoracic Anesthesia     Open Access  
Egyptian J. of Cataract and Refractive Surgery     Open Access   (Followers: 1, SJR: 1.799, CiteScore: 2)
Egyptian J. of Chest Diseases and Tuberculosis     Open Access   (Followers: 3, SJR: 0.155, CiteScore: 0)
Egyptian J. of Dermatology and Venerology     Open Access   (Followers: 1)
Egyptian J. of Haematology     Open Access   (Followers: 1)
Egyptian J. of Internal Medicine     Open Access   (Followers: 1)
Egyptian J. of Obesity, Diabetes and Endocrinology     Open Access   (Followers: 1)
Egyptian J. of Otolaryngology     Open Access   (Followers: 2)
Egyptian J. of Psychiatry     Open Access   (Followers: 1)
Egyptian J. of Surgery     Open Access   (Followers: 1)
Egyptian Nursing J.     Open Access  
Egyptian Orthopaedic J.     Open Access   (Followers: 2)
Egyptian Pharmaceutical J.     Open Access   (Followers: 3)
Egyptian Retina J.     Open Access  
Egyptian Rheumatology and Rehabilitation     Open Access   (Followers: 2)
Endodontology     Open Access  
Endoscopic Ultrasound     Open Access   (SJR: 0.822, CiteScore: 2)
Environmental Disease     Open Access   (Followers: 3)
Eurasian J. of Pulmonology     Open Access  
European J. of Dentistry     Open Access   (Followers: 3, SJR: 0.749, CiteScore: 2)
European J. of General Dentistry     Open Access   (Followers: 1, SJR: 0.12, CiteScore: 0)
European J. of Prosthodontics     Open Access   (Followers: 4)
European J. of Psychology and Educational Studies     Open Access   (Followers: 11, SJR: 0.113, CiteScore: 0)
Fertility Science and Research     Open Access  
Formosan J. of Surgery     Open Access   (SJR: 0.112, CiteScore: 0)
Genome Integrity     Open Access   (Followers: 2, SJR: 0.153, CiteScore: 0)
Glioma     Open Access  
Global J. of Transfusion Medicine     Open Access   (Followers: 1)
Gynecology and Minimally Invasive Therapy     Open Access   (SJR: 0.311, CiteScore: 1)
Hamdan Medical J.     Open Access  
Heart and Mind     Open Access  
Heart India     Open Access   (Followers: 1)
Heart Views     Open Access   (Followers: 2)
Hepatitis B Annual     Open Access   (Followers: 3)
Ibnosina J. of Medicine and Biomedical Sciences     Open Access  
IJS Short Reports     Open Access  
Imam J. of Applied Sciences     Open Access  
Indian Dermatology Online J.     Open Access   (Followers: 3)
Indian J. of Allergy, Asthma and Immunology     Open Access   (Followers: 1)
Indian J. of Anaesthesia     Open Access   (Followers: 7, SJR: 0.478, CiteScore: 1)
Indian J. of Burns     Open Access   (Followers: 1)
Indian J. of Cancer     Open Access   (Followers: 1, SJR: 0.361, CiteScore: 1)
Indian J. of Cerebral Palsy     Open Access   (Followers: 1)
Indian J. of Community Medicine     Open Access   (Followers: 2, SJR: 0.37, CiteScore: 1)
Indian J. of Dental Research     Open Access   (Followers: 5, SJR: 0.266, CiteScore: 1)
Indian J. of Dental Sciences     Open Access  
Indian J. of Dentistry     Open Access   (Followers: 1)
Indian J. of Dermatology     Open Access   (Followers: 2, SJR: 0.468, CiteScore: 1)
Indian J. of Dermatology, Venereology and Leprology     Open Access   (Followers: 4, SJR: 0.445, CiteScore: 1)
Indian J. of Dermatopathology and Diagnostic Dermatology     Open Access  
Indian J. of Drugs in Dermatology     Open Access   (Followers: 1, SJR: 0.791, CiteScore: 1)
Indian J. of Endocrinology and Metabolism     Open Access   (Followers: 4, SJR: 0.568, CiteScore: 1)
Indian J. of Health Sciences and Biomedical Research KLEU     Open Access   (Followers: 2)
Indian J. of Medical and Paediatric Oncology     Open Access   (SJR: 0.425, CiteScore: 1)
Indian J. of Medical Microbiology     Open Access   (Followers: 2, SJR: 0.503, CiteScore: 1)
Indian J. of Medical Research     Open Access   (Followers: 4, SJR: 0.656, CiteScore: 1)
Indian J. of Medical Sciences     Open Access   (Followers: 2, SJR: 0.102, CiteScore: 0)
Indian J. of Multidisciplinary Dentistry     Open Access   (Followers: 1)
Indian J. of Nephrology     Open Access   (Followers: 2, SJR: 0.347, CiteScore: 1)
Indian J. of Nuclear Medicine     Open Access   (Followers: 2, SJR: 0.23, CiteScore: 0)
Indian J. of Occupational and Environmental Medicine     Open Access   (Followers: 3, SJR: 0.225, CiteScore: 1)
Indian J. of Ophthalmology     Open Access   (Followers: 4, SJR: 0.498, CiteScore: 1)
Indian J. of Oral Health and Research     Open Access  
Indian J. of Oral Sciences     Open Access   (Followers: 1)
Indian J. of Orthopaedics     Open Access   (Followers: 8, SJR: 0.392, CiteScore: 1)
Indian J. of Otology     Open Access   (Followers: 1, SJR: 0.199, CiteScore: 0)
Indian J. of Paediatric Dermatology     Open Access   (Followers: 2)
Indian J. of Pain     Open Access   (Followers: 2)
Indian J. of Palliative Care     Open Access   (Followers: 6, SJR: 0.454, CiteScore: 1)
Indian J. of Pathology and Microbiology     Open Access   (Followers: 3, SJR: 0.276, CiteScore: 1)
Indian J. of Pharmacology     Open Access   (SJR: 0.412, CiteScore: 1)
Indian J. of Plastic Surgery     Open Access   (Followers: 13, SJR: 0.311, CiteScore: 0)
Indian J. of Psychiatry     Open Access   (Followers: 2, SJR: 0.408, CiteScore: 1)
Indian J. of Psychological Medicine     Open Access   (SJR: 0.368, CiteScore: 1)
Indian J. of Public Health     Open Access   (Followers: 1)
Indian J. of Radiology and Imaging     Open Access   (Followers: 4)
Indian J. of Research in Homoeopathy     Open Access  
Indian J. of Respiratory Care     Open Access  
Indian J. of Rheumatology     Open Access   (Followers: 1, SJR: 0.119, CiteScore: 0)
Indian J. of Sexually Transmitted Diseases and AIDS     Open Access   (Followers: 2, SJR: 0.34, CiteScore: 0)
Indian J. of Social Psychiatry     Open Access   (Followers: 1)
Indian J. of Transplantation     Open Access  
Indian J. of Urology     Open Access   (Followers: 4, SJR: 0.434, CiteScore: 1)
Indian J. of Vascular and Endovascular Surgery     Open Access   (Followers: 2)
Indian Spine J.     Open Access  
Industrial Psychiatry J.     Open Access   (Followers: 2)
Intervention     Open Access   (Followers: 1)
Intl. Archives of Health Sciences     Open Access  
Intl. J. of Abdominal Wall and Hernia Surgery     Open Access   (Followers: 1)
Intl. J. of Academic Medicine     Open Access  
Intl. J. of Advanced Medical and Health Research     Open Access  
Intl. J. of Applied and Basic Medical Research     Open Access  
Intl. J. of Clinical and Experimental Physiology     Open Access   (Followers: 1)
Intl. J. of Clinicopathological Correlation     Open Access   (Followers: 1)
Intl. J. of Community Dentistry     Open Access  
Intl. J. of Critical Illness and Injury Science     Open Access   (Followers: 1, SJR: 0.192, CiteScore: 0)
Intl. J. of Educational and Psychological Researches     Open Access   (Followers: 4)
Intl. J. of Environmental Health Engineering     Open Access   (Followers: 1)
Intl. J. of Forensic Odontology     Open Access   (Followers: 1)
Intl. J. of Green Pharmacy     Open Access   (Followers: 5, SJR: 0.142, CiteScore: 0)
Intl. J. of Growth Factors and Stem Cells in Dentistry     Open Access  
Intl. J. of Health & Allied Sciences     Open Access   (Followers: 3)
Intl. J. of Health System and Disaster Management     Open Access   (Followers: 3)
Intl. J. of Heart Rhythm     Open Access  
Intl. J. of Medicine and Public Health     Open Access   (Followers: 6)
Intl. J. of Mycobacteriology     Open Access   (SJR: 0.535, CiteScore: 1)
Intl. J. of Noncommunicable Diseases     Open Access  
Intl. J. of Nutrition, Pharmacology, Neurological Diseases     Open Access   (Followers: 4, SJR: 0.17, CiteScore: 0)
Intl. J. of Oral Health Sciences     Open Access   (Followers: 3)
Intl. J. of Orofacial Biology     Open Access   (Followers: 1)
Intl. J. of Orofacial Research     Open Access   (Followers: 2)
Intl. J. of Orthodontic Rehabilitation     Open Access   (Followers: 1)
Intl. J. of Pedodontic Rehabilitation     Open Access  
Intl. J. of Pharmaceutical Investigation     Open Access   (Followers: 2)
Intl. J. of Preventive Medicine     Open Access   (Followers: 1, SJR: 0.623, CiteScore: 1)
Intl. J. of Shoulder Surgery     Open Access   (Followers: 5, SJR: 0.653, CiteScore: 1)
Intl. J. of the Cardiovascular Academy     Open Access   (SJR: 0.105, CiteScore: 0)
Intl. J. of Trichology     Open Access   (SJR: 0.4, CiteScore: 1)
Intl. J. of Yoga     Open Access   (Followers: 14)
Intl. J. of Yoga : Philosophy, Psychology and Parapsychology     Open Access   (Followers: 6)
Iranian J. of Nursing and Midwifery Research     Open Access   (Followers: 3)
Iraqi J. of Hematology     Open Access  
J. of Academy of Medical Sciences     Open Access  

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AYU : An international quarterly journal of research in Ayurveda
Number of Followers: 6  

  This is an Open Access Journal Open Access journal
ISSN (Print) 0974-8520 - ISSN (Online) 0976-9382
Published by Medknow Publishers Homepage  [426 journals]
  • Pharmacovigilance: An ayurvedic viewpoint

    • Authors: Mandip Goyal
      Pages: 197 - 198
      Abstract: Mandip Goyal
      AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):197-198

      Citation: AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):197-198
      PubDate: Fri,5 Jul 2019
      DOI: 10.4103/ayu.AYU_82_19
      Issue No: Vol. 39, No. 4 (2019)
       
  • Diet and lifestyle-related factors associated with Apathyanimittaja
           Prameha (type 2 diabetes): A cross-sectional survey study

    • Authors: Akhilesh Shukla, AS Baghel, Mahesh Vyas
      Pages: 199 - 207
      Abstract: Akhilesh Shukla, AS Baghel, Mahesh Vyas
      AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):199-207
      Background: Lifestyle disorders are the leading cause of death and disability worldwide. Type 2 diabetes is one such disease with high incidence in low- and middle-income countries such as India. Changed lifestyle, lack of exercise, increased consumption of fatty, fast-food items, improper dietary habits and sedentary life are the main contributory factors for this, which are showing upward trend in India. Aims and Objectives: The aim of the study is to identify the lifestyle factors, physical activities and psychological factors associated with type 2 diabetes among the patient aged between 20-60 years. Materials and Methods: A cross-sectional survey study was conducted on selected 150 patients of type 2 diabetes within 1 year of diagnosis. A survey questionnaire was used to collect the data for fulfilling the aims and objectives of the study. Results and Observations: 150 patients of type 2 diabetes were observed on various dietary factors, physical activities and life style factors. Conclusion: On the basis of survey psychological factor association with type 2 diabetes and dietary factors, physical activities and psychological factors observed in survey study. The obtained data exposed that intake of heavy, high fatty food, physical inactivity, day sleep and psychological distress as the main lifestyle factors associated with type 2 diabetes.
      Citation: AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):199-207
      PubDate: Fri,5 Jul 2019
      DOI: 10.4103/ayu.AYU_108_16
      Issue No: Vol. 39, No. 4 (2019)
       
  • Management of Padadari (cracked feet) with Rakta Snuhi (Euphorbia
           caducifolia Haines.) based formulation: An open-labeled clinical study

    • Authors: Shashi Gupta, Rabinarayan Acharya
      Pages: 208 - 212
      Abstract: Shashi Gupta, Rabinarayan Acharya
      AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):208-212
      Introduction: Ayurveda considers, Padadari (cracked feet) as disease condition, under Kshudra Kushtha (minor diseases of skin). Cracked feet also known as heel fissures is a common foot problem characterized by yellowish color of the skin on the heel of the foot, hard skin growth, hardening and cracks in the feet associated with pain, bleeding or itching. Vaidya Manorama, Ayurvedic compendia, recommended Snuhi oil as a remedy for Padadari. An open-labeled clinical trial has been conducted to evaluate the effect of Rakta Snuhi-based formulation in Padadari. Materials and Methods: Snuhi oil was prepared by mixing Saindhava Lavana (Rock salt) 24 g; 300 ml latex of Rakta Snuhi (Euphorbia caducifolia); 4.8 l. of water, Sarshapa Taila (mustard oil) 1.2 l. and further heating of oil, following classical guidelines of Sneha Kalpana. For better acceptability, the medicated oil was then gradually mixed with “Aerosil,” a thickener, for converting the mixture into gel form. Twenty-six patients, diagnosed with Padadari, were treated by applying 3 g (or as per requirement) of Rakta Snuhi Ksheera gel twice daily for 21 consecutive days. Results: Response to the treatment was recorded on a weekly basis and therapeutic effect was evaluated through symptomatic relief. Conclusion: The study yielded statistically highly significant results in symptoms such as cracks associated with pain (P < 0.001), Rukshata (dryness) (P < 0.001) and Kandu (itching) (P < 0.001).
      Citation: AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):208-212
      PubDate: Fri,5 Jul 2019
      DOI: 10.4103/ayu.AYU_57_18
      Issue No: Vol. 39, No. 4 (2019)
       
  • Efficacy of Apamarga Kshara application and Sclerotherapy in the
           management of Arsha (1st and 2nd degree piles) – An open-labeled,
           randomized, controlled clinical trial

    • Authors: Bijendra Shah, Tukaram Sambhaji Dudhamal
      Pages: 213 - 219
      Abstract: Bijendra Shah, Tukaram Sambhaji Dudhamal
      AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):213-219
      Background: Anorectal disorders are progressively increasing in the society. Out of many of the causes, some important are sedentary lifestyle, irregular and inappropriate diet, prolonged sitting or standing, and certain psychological disturbances. The prime cause of anorectal disorders is the instability of Jatharagni (digestive system), which further leads to constipation. Aim and Objective: To compare the efficacy of Apamarga Kshara application (AKA) and sclerotherapy (SCL) in the management of Arsha (1st and 2nd degree piles). Materials and Methods: In this study, 50 patients of Arsha (1st and 2nd degree piles) were selected and randomly allocated into two groups. In group AKA (n = 25), Apamarga Tikshna Kshara (alkaline of Achyranthes aspera linn.) application was done and in group SCL (n = 25), SCL was done in 1st and 2nd degree piles. The study was open prospective interventional clinical trial. Patients were assessed for relief in signs and symptoms at weekly interval for a month and another 1 month as follow-up period. Results: Patients of group SCL took more time than the patients of group AKA to get reduction in size of pile mass. In group SCL, maximum relief in bleeding as well as discharge per rectum was reported. AKA provided better results in ceasing the bleeding per rectum as well as reducing prolapse piles, than SCL. Conclusion: The study concluded that AKA is a effective procedure of choice for the management of 1st and 2nd degree internal piles as compared to SCL.
      Citation: AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):213-219
      PubDate: Fri,5 Jul 2019
      DOI: 10.4103/ayu.AYU_147_18
      Issue No: Vol. 39, No. 4 (2019)
       
  • Natural stains Zingiber officinale Roscoe (ginger) and Curcuma longa L.
           (turmeric) – A substitute to eosin

    • Authors: Archana Sudhakaran, Kaveri Hallikeri, Biji Babu
      Pages: 220 - 225
      Abstract: Archana Sudhakaran, Kaveri Hallikeri, Biji Babu
      AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):220-225
      Background: Stained slides are of the utmost source of information in pathology. The routine stains utilize synthetic dyes which pose various health hazards which necessitate the importance of natural extracts as a histological stain. Aims: The aim of this study is to compare the efficacy of ginger and turmeric extracts as histological dyes in tissues keeping eosin as standard. Objectives: The objective of this study is to compare the staining potential, intensity, specificity, and shelf life of ginger and termuric extract dyes. Materials and Methods: Extracts of fresh rhizomes of Zingiber officinale Roscoe and Curcuma longa L. were obtained by dissolving them in alcohol, which was used to stain sections of 25 cases. Observer 1 compared the staining intensity, while observers 2 and 3 assessed preset parameters at regular intervals and subjected to Kappa statistics and Mann–Whitney U-test. Results: Z. officinale and C. longa solutions had pH 4–5 and temperature 24°C–27°C. Z. officinale showed better staining intensity and specificity to the cytoplasm and basic components of connective tissue as compared to C. longa. Crispness (P = 0.01) and background staining (P = 0.05) showed a significant difference. Shelf life of Z. officinale was better than C. longa. Conclusion: Z. officinale gave a better staining than C. longa and was found to be closest to eosin and is easily available, cost-effective and biodegradable.
      Citation: AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):220-225
      PubDate: Fri,5 Jul 2019
      DOI: 10.4103/ayu.AYU_232_17
      Issue No: Vol. 39, No. 4 (2019)
       
  • Antibacterial and anti-inflammatory properties of Plantago ovata Forssk.
           leaves and seeds against periodontal pathogens: An in vitro study

    • Authors: P Ravi Tejeshwar Reddy, KV Vandana, Shobha Prakash
      Pages: 226 - 229
      Abstract: P Ravi Tejeshwar Reddy, KV Vandana, Shobha Prakash
      AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):226-229
      Background: Plantago commonly called as Isabgol (Plantago ovata Forssk.) is a perennial herb that belongs to the family Plantaginaceae. A range of biological activities has been found from plant extracts, including wound healing activity, anti-inflammatory, analgesic, antioxidant, weak antibiotic, immunomodulating and anti-ulcerogenic activity. Periodontal disease is a complex condition as a result of interaction between microorganisms and host inflammatory mediators. Hence, the extract of Isabgol is tested for its antibacterial and anti-inflammatory properties against periodontal disease. Aim: The aim of this in vitro study is to evaluate the antibacterial property of Isabgol leaves and seeds against periodontal pathogens, namely Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, and Fusobacterium nucleatum and anti-inflammatory property against matrix metalloproteinase-2 (MMP-2) and MMP-9. Materials and Methods: In this in vitro study, aqueous extract of Isabgol is tested for its antibacterial property against the stock cultures of specified periodontal pathogens using the tube dilution method and anti-inflammatory property against MMP-2 and MMP-9 using zymogen gel electrography. Results: Minimum concentration at which the sensitivity of A. actinomycetemcomitans, P. gingivalis, P. intermedia, and F. nucleatum for the extract observed was 50 μl/ml, 0.8 μl/ml, 0.4 μl/ml and 12.5 μl/ml, respectively, concentrations below these showed no effect on the microorganisms. Zymogen electrographic test for anti-inflammatory activity showed percentage inhibition of 30% and 40% against MMP-2 and MMP-9, respectively. Conclusion: Isabgol is effective against the periodontal pathogens and inflammatory mediators which are responsible for periodontal disease.
      Citation: AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):226-229
      PubDate: Fri,5 Jul 2019
      DOI: 10.4103/ayu.AYU_176_16
      Issue No: Vol. 39, No. 4 (2019)
       
  • Triethylene glycol-like effects of Ashwagandha (Withania somnifera (L.)
           Dunal) root extract devoid of withanolides in stressed mice

    • Authors: Amitabha Dey, Shyam Sunder Chatterjee, Vikas Kumar
      Pages: 230 - 238
      Abstract: Amitabha Dey, Shyam Sunder Chatterjee, Vikas Kumar
      AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):230-238
      Background: The objective of the study is to compare stress resistance-promoting effect of triethylene glycol (TEG) and root extract of Ashwagandha (Withania somnifera) i.e. withanolide-free root extract of Withania somnifera (WFWS). Materials and Methods: Mice groups treated orally with 10 mg/kg TEG or WFWS (3.3, 10, 33.3, or 100 mg/kg) for 12 consecutive days were subjected to foot shock stress-triggered hyperthermia test on the 1st, 5th, 7th and 10th day and to marble-burying test on the following 2 days. Effects of treatment on stress-triggered alteration in body weight, core temperature, blood glucose, insulin and cortisol level were quantified and statistically analyzed. Results: WFWS doses up to 10 mg/kg/day were as effective as TEG in affording protection against stress-triggered alteration in body weight, core temperature and marble-burying behavior. Protection against stress-triggered alteration in blood glucose and insulin level, as well as antidepressants or anxiolytic-like activities in the behavioral test, were observed in the higher two WFWS doses (33.3 and 100 mg/kg) treated groups only. Conclusion: Ashwagandha metabolites other than withanolides contribute to its stress resistance increasing effects. The observations suggest that modulation of physiological functions of gut microbiota may be involved in the mode of action of Withania somnifera root extracts.
      Citation: AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):230-238
      PubDate: Fri,5 Jul 2019
      DOI: 10.4103/ayu.AYU_219_16
      Issue No: Vol. 39, No. 4 (2019)
       
  • In vitro anti-inflammatory activity of Ficus racemosa L. bark using
           albumin denaturation method

    • Authors: Sharmila Dharmadeva, Lahiru Sandaruwan Galgamuwa, C Prasadinie, Nishantha Kumarasinghe
      Pages: 239 - 242
      Abstract: Sharmila Dharmadeva, Lahiru Sandaruwan Galgamuwa, C Prasadinie, Nishantha Kumarasinghe
      AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):239-242
      Introduction: In Ayurveda, many natural plant compounds are used to inhibit inflammatory pathways for centuries with less side effects. Different parts of Ficus racemosa L. (Udumber) plant are used in Ayurveda for many diseases. However, few studies have been conducted to evaluate pharmacological activities of F. racemosa. Objective: The objective of the study was to in vitro analyze anti-inflammatory property of F. racemosa bark using albumin denaturation activity. Methodology: F. racemosa bark extraction was performed using cold water and hot water. The concentration gradient of extracts was prepared using egg albumin and phosphate-buffered saline. The extract was incubated in a water bath at 37°C for 15 min and was heated at 70°C for 5 min. One nonsteroidal anti-inflammatory drug and one steroid were used as reference drugs. The percentage inhibition of protein denaturation was calculated. Results: The inhibition rate of egg albumin denaturation for water extraction increased gradually with concentration. Significantly higher inhibition was showed in hot water extracts than cold water extracts at the concentration of 0.01 μg/ml and 0.1 μg/ml. In addition, the inhibition rate of water extraction was significantly higher than the reference drugs (P < 0.05). Conclusion: Anti-inflammatory activity increases with the concentration of F. racemosa bark. Furthermore, the action of this plant is significantly higher than the reference drugs.
      Citation: AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):239-242
      PubDate: Fri,5 Jul 2019
      DOI: 10.4103/ayu.AYU_27_18
      Issue No: Vol. 39, No. 4 (2019)
       
  • Evaluation of anti-inflammatory effect of Varanadi Kashayam (decoction) in
           THP-1-derived macrophages

    • Authors: JU Chinchu, Mohind C Mohan, S J Rahitha Devi, B Prakash Kumar
      Pages: 243 - 249
      Abstract: JU Chinchu, Mohind C Mohan, S J Rahitha Devi, B Prakash Kumar
      AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):243-249
      Background: Varanadi Kashayam is an Ayurvedic polyherbal decoction containing 16 ingredients, for which the mechanisms of action involved in controlling chronic inflammatory conditions have not been evaluated. The inhibition of release of proinflammatory cytokines by lipopolysaccharide (LPS)-stimulated monocytes/macrophages is an ideal in vitro model for identifying anti-inflammatory molecules. Aim: The aim of the study is to determine the anti-inflammatory effect of Varanadi Kashayam in THP-1-derived macrophages. Materials and Methods: The efficacy of Varanadi Kashayam on monocyte cell differentiation was determined by quantitative polymerase chain reaction to assess the expression of differentiation markers MMP-9, CD36, CD11b and CD14. Further Varanadi Kashayam treated THP-1 macrophages were induced with LPS and the production of proinflammatory cytokines tumor necrosis factor-alpha (TNF-α) and interleukin-1beta (IL-1β) were measured and corresponding genes expressions were quantified. Results: The results indicate that Varanadi Kashayam reduced the differentiation of THP-1 monocytes to macrophages and downregulated the expression of cell surface markers. Furthermore, it could decrease the release of proinflammatory cytokines from LPS-induced THP-1 macrophages and downregulated the expression of TNF-α and IL-1β genes. Conclusion: The results obtained from this study suggest a possible mechanism of action of the herbal decoction in inflammatory processes and opens up the possibilities of identifying bioactive lead molecules with anti-inflammatory potentials.
      Citation: AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):243-249
      PubDate: Fri,5 Jul 2019
      DOI: 10.4103/ayu.AYU_53_18
      Issue No: Vol. 39, No. 4 (2019)
       
  • A clinical study on the effect of Triphaladi Kala Basti with Arjuna
           Punarnavadi Ghanavati in the management of essential hypertension

    • Authors: Ujwala Samadhan Hivale, Santosh Kumar Bhatted, Meera K Bhojani, Nirmal Bhusal
      Pages: 250 - 255
      Abstract: Ujwala Samadhan Hivale, Santosh Kumar Bhatted, Meera K Bhojani, Nirmal Bhusal
      AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):250-255
      Introduction: Hypertension, one of the grave conditions, accounts for 6% of deaths worldwide. In 2010 increased blood pressure was the cause of an estimated 9.4 million deaths. According to Ayurveda, systemic arterial hypertension can be considered as Tridoshaja condition with predominance of Vata and Pitta along with invovment of Rasa, Rakta and Meda. Basti Karma a medicated enema procedure is the best treatment for vitiated Vata Dosha and it regulates the movement of Vata Dosha. Objectives: The present study was conducted to evaluate effect of Triphaladi Kala Basti procedure given along with Arjuna Punarnavadi Ghanavati in the management of essential hypertension. Materials and Methods: Fifteen patients who were diagnosed cases of essential hypertension as per the 7th JNC and World Health Organization criteria for diagnosis of hypertension were treated with Triphaladi Basti followed by oral administration of Arjuna Punarnavadi Ghanavati. Results: Administration of Basti and Arjuna Punarnavadi Ghanavati were effective in reducing both systolic and diastolic blood pressure level which was highly significant (P < 0.001). Conclusion: Triphaladi Kala Basti procedure along with oral administration of Arjuna Punarnavadi Ghanavati is moderatly effective in management of systemic arterial hypertension.
      Citation: AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):250-255
      PubDate: Fri,5 Jul 2019
      DOI: 10.4103/ayu.AYU_184_17
      Issue No: Vol. 39, No. 4 (2019)
       
  • Kaphaja, Kapha-Pittaja Prakriti, methylenetetrahydrofolate reductase C677T
           allele and type 2 diabetes

    • Authors: Beuy Joob, Viroj Wiwanitkit
      Pages: 256 - 256
      Abstract: Beuy Joob, Viroj Wiwanitkit
      AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):256-256

      Citation: AYU (An international quarterly journal of research in Ayurveda) 2018 39(4):256-256
      PubDate: Fri,5 Jul 2019
      DOI: 10.4103/ayu.AYU_44_19
      Issue No: Vol. 39, No. 4 (2019)
       
 
 
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