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Publisher: Medknow Publishers   (Total: 355 journals)

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Showing 1 - 200 of 355 Journals sorted alphabetically
Advanced Arab Academy of Audio-Vestibulogy J.     Open Access  
Advances in Human Biology     Open Access   (Followers: 1)
African J. for Infertility and Assisted Conception     Open Access  
African J. of Business Ethics     Open Access   (Followers: 6)
African J. of Medical and Health Sciences     Open Access   (Followers: 2)
African J. of Paediatric Surgery     Open Access   (Followers: 7, SJR: 0.269, h-index: 10)
African J. of Trauma     Open Access  
Ain-Shams J. of Anaesthesiology     Open Access   (Followers: 3)
Al-Azhar Assiut Medical J.     Open Access  
Al-Basar Intl. J. of Ophthalmology     Open Access   (Followers: 1)
Ancient Science of Life     Open Access   (Followers: 6)
Anesthesia : Essays and Researches     Open Access   (Followers: 8)
Annals of African Medicine     Open Access   (Followers: 1, SJR: 0.331, h-index: 15)
Annals of Bioanthropology     Open Access   (Followers: 3)
Annals of Cardiac Anaesthesia     Open Access   (Followers: 14, SJR: 0.408, h-index: 15)
Annals of Indian Academy of Neurology     Open Access   (Followers: 3, SJR: 0.308, h-index: 14)
Annals of Maxillofacial Surgery     Open Access   (Followers: 6)
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 7, SJR: 0.441, h-index: 10)
Annals of Saudi Medicine     Open Access   (SJR: 0.24, h-index: 29)
Annals of Thoracic Medicine     Open Access   (Followers: 4, SJR: 0.388, h-index: 19)
Annals of Tropical Medicine and Public Health     Open Access   (Followers: 15, SJR: 0.148, h-index: 5)
APOS Trends in Orthodontics     Open Access   (Followers: 1)
Arab J. of Interventional Radiology     Open Access  
Archives of Intl. Surgery     Open Access   (Followers: 9)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Archives of Pharmacy Practice     Open Access   (Followers: 6)
Asia Pacific J. of Clinical Trials : Nervous System Diseases     Open Access  
Asia-Pacific J. of Oncology Nursing     Open Access   (Followers: 3)
Asian J. of Andrology     Open Access   (Followers: 1, SJR: 0.879, h-index: 49)
Asian J. of Neurosurgery     Open Access   (Followers: 2)
Asian J. of Oncology     Open Access   (Followers: 1)
Asian J. of Transfusion Science     Open Access   (Followers: 2, SJR: 0.362, h-index: 10)
Astrocyte     Open Access  
Avicenna J. of Medicine     Open Access   (Followers: 1)
AYU : An international quarterly journal of research in Ayurveda     Open Access   (Followers: 6)
Benha Medical J.     Open Access  
BLDE University J. of Health Sciences     Open Access  
Brain Circulation     Open Access  
Bulletin of Faculty of Physical Therapy     Open Access   (Followers: 1)
Cancer Translational Medicine     Open Access   (Followers: 1)
CHRISMED J. of Health and Research     Open Access  
Clinical Dermatology Review     Open Access   (Followers: 1)
Clinical Trials in Degenerative Diseases     Open Access  
Clinical Trials in Orthopedic Disorders     Open Access   (Followers: 1)
Community Acquired Infection     Open Access  
Conservation and Society     Open Access   (Followers: 12, SJR: 0.82, h-index: 12)
Contemporary Clinical Dentistry     Open Access   (Followers: 4)
Current Medical Issues     Open Access   (Followers: 1)
CytoJ.     Open Access   (Followers: 2, SJR: 0.339, h-index: 19)
Delta J. of Ophthalmology     Open Access  
Dental Hypotheses     Open Access   (Followers: 3, SJR: 0.131, h-index: 4)
Dental Research J.     Open Access   (Followers: 9)
Dentistry and Medical Research     Open Access  
Digital Medicine     Open Access  
Drug Development and Therapeutics     Open Access  
Education for Health     Open Access   (Followers: 5, SJR: 0.205, h-index: 22)
Egyptian J. of Bronchology     Open Access  
Egyptian J. of Cardiothoracic Anesthesia     Open Access  
Egyptian J. of Cataract and Refractive Surgery     Open Access   (Followers: 1)
Egyptian J. of Dermatology and Venerology     Open Access   (Followers: 1)
Egyptian J. of Haematology     Open Access  
Egyptian J. of Internal Medicine     Open Access   (Followers: 1)
Egyptian J. of Neurology, Psychiatry and Neurosurgery     Open Access   (Followers: 1, SJR: 0.121, h-index: 3)
Egyptian J. of Obesity, Diabetes and Endocrinology     Open Access  
Egyptian J. of Otolaryngology     Open Access   (Followers: 2)
Egyptian J. of Psychiatry     Open Access   (Followers: 2)
Egyptian J. of Surgery     Open Access   (Followers: 1)
Egyptian Orthopaedic J.     Open Access  
Egyptian Pharmaceutical J.     Open Access  
Egyptian Retina J.     Open Access  
Egyptian Rheumatology and Rehabilitation     Open Access  
Endodontology     Open Access  
Endoscopic Ultrasound     Open Access   (SJR: 0.473, h-index: 8)
Environmental Disease     Open Access   (Followers: 2)
European J. of Dentistry     Open Access   (Followers: 2, SJR: 0.496, h-index: 11)
European J. of General Dentistry     Open Access   (Followers: 1)
European J. of Prosthodontics     Open Access   (Followers: 2)
European J. of Psychology and Educational Studies     Open Access   (Followers: 8)
Fertility Science and Research     Open Access  
Formosan J. of Surgery     Open Access   (SJR: 0.107, h-index: 5)
Genome Integrity     Open Access   (Followers: 4, SJR: 1.227, h-index: 12)
Global J. of Transfusion Medicine     Open Access   (Followers: 2)
Heart India     Open Access   (Followers: 1)
Heart Views     Open Access   (Followers: 2)
Hepatitis B Annual     Open Access   (Followers: 3)
IJS Short Reports     Open Access  
Indian Anaesthetists Forum     Open Access  
Indian Dermatology Online J.     Open Access   (Followers: 3)
Indian J. of Allergy, Asthma and Immunology     Open Access   (Followers: 1)
Indian J. of Anaesthesia     Open Access   (Followers: 8, SJR: 0.302, h-index: 13)
Indian J. of Burns     Open Access   (Followers: 1)
Indian J. of Cancer     Open Access   (SJR: 0.318, h-index: 26)
Indian J. of Cerebral Palsy     Open Access   (Followers: 1)
Indian J. of Community Medicine     Open Access   (Followers: 2, SJR: 0.618, h-index: 16)
Indian J. of Critical Care Medicine     Open Access   (Followers: 2, SJR: 0.307, h-index: 16)
Indian J. of Dental Research     Open Access   (Followers: 4, SJR: 0.243, h-index: 24)
Indian J. of Dental Sciences     Open Access  
Indian J. of Dentistry     Open Access   (Followers: 1)
Indian J. of Dermatology     Open Access   (Followers: 2, SJR: 0.448, h-index: 16)
Indian J. of Dermatology, Venereology and Leprology     Open Access   (Followers: 3, SJR: 0.563, h-index: 29)
Indian J. of Dermatopathology and Diagnostic Dermatology     Open Access  
Indian J. of Drugs in Dermatology     Open Access   (Followers: 1)
Indian J. of Endocrinology and Metabolism     Open Access   (Followers: 4)
Indian J. of Health Sciences     Open Access   (Followers: 2)
Indian J. of Medical and Paediatric Oncology     Open Access   (SJR: 0.292, h-index: 9)
Indian J. of Medical Microbiology     Open Access   (Followers: 1, SJR: 0.53, h-index: 34)
Indian J. of Medical Research     Open Access   (Followers: 4, SJR: 0.716, h-index: 60)
Indian J. of Medical Sciences     Open Access   (Followers: 2, SJR: 0.207, h-index: 31)
Indian J. of Multidisciplinary Dentistry     Open Access   (Followers: 1)
Indian J. of Nephrology     Open Access   (Followers: 2, SJR: 0.233, h-index: 12)
Indian J. of Nuclear Medicine     Open Access   (Followers: 2, SJR: 0.213, h-index: 5)
Indian J. of Occupational and Environmental Medicine     Open Access   (Followers: 4, SJR: 0.203, h-index: 13)
Indian J. of Ophthalmology     Open Access   (Followers: 5, SJR: 0.536, h-index: 34)
Indian J. of Oral Health and Research     Open Access  
Indian J. of Oral Sciences     Open Access   (Followers: 1)
Indian J. of Orthopaedics     Open Access   (Followers: 9, SJR: 0.393, h-index: 15)
Indian J. of Otology     Open Access   (Followers: 1, SJR: 0.218, h-index: 5)
Indian J. of Paediatric Dermatology     Open Access   (Followers: 2)
Indian J. of Pain     Open Access   (Followers: 1)
Indian J. of Palliative Care     Open Access   (Followers: 5, SJR: 0.35, h-index: 12)
Indian J. of Pathology and Microbiology     Open Access   (Followers: 1, SJR: 0.285, h-index: 22)
Indian J. of Pharmacology     Open Access   (SJR: 0.347, h-index: 44)
Indian J. of Plastic Surgery     Open Access   (Followers: 12, SJR: 0.303, h-index: 13)
Indian J. of Psychiatry     Open Access   (Followers: 3, SJR: 0.496, h-index: 15)
Indian J. of Psychological Medicine     Open Access   (Followers: 1, SJR: 0.344, h-index: 9)
Indian J. of Public Health     Open Access   (Followers: 1, SJR: 0.444, h-index: 17)
Indian J. of Radiology and Imaging     Open Access   (Followers: 4, SJR: 0.253, h-index: 14)
Indian J. of Research in Homoeopathy     Open Access  
Indian J. of Rheumatology     Open Access   (SJR: 0.169, h-index: 7)
Indian J. of Sexually Transmitted Diseases and AIDS     Open Access   (Followers: 2, SJR: 0.313, h-index: 9)
Indian J. of Social Psychiatry     Open Access   (Followers: 2)
Indian J. of Urology     Open Access   (Followers: 3, SJR: 0.366, h-index: 16)
Indian J. of Vascular and Endovascular Surgery     Open Access   (Followers: 2)
Industrial Psychiatry J.     Open Access   (Followers: 2)
Intl. J. of Academic Medicine     Open Access  
Intl. J. of Advanced Medical and Health Research     Open Access  
Intl. J. of Applied and Basic Medical Research     Open Access  
Intl. J. of Clinical and Experimental Physiology     Open Access   (Followers: 1)
Intl. J. of Critical Illness and Injury Science     Open Access   (Followers: 1)
Intl. J. of Educational and Psychological Researches     Open Access   (Followers: 4)
Intl. J. of Environmental Health Engineering     Open Access   (Followers: 1)
Intl. J. of Forensic Odontology     Open Access   (Followers: 1)
Intl. J. of Green Pharmacy     Open Access   (Followers: 4, SJR: 0.229, h-index: 13)
Intl. J. of Health & Allied Sciences     Open Access   (Followers: 3)
Intl. J. of Health System and Disaster Management     Open Access   (Followers: 3)
Intl. J. of Heart Rhythm     Open Access  
Intl. J. of Medicine and Public Health     Open Access   (Followers: 7)
Intl. J. of Mycobacteriology     Open Access   (SJR: 0.239, h-index: 4)
Intl. J. of Noncommunicable Diseases     Open Access  
Intl. J. of Nutrition, Pharmacology, Neurological Diseases     Open Access   (Followers: 4)
Intl. J. of Oral Health Sciences     Open Access   (Followers: 1)
Intl. J. of Orthodontic Rehabilitation     Open Access  
Intl. J. of Pedodontic Rehabilitation     Open Access  
Intl. J. of Pharmaceutical Investigation     Open Access   (Followers: 1)
Intl. J. of Preventive Medicine     Open Access   (Followers: 1, SJR: 0.523, h-index: 15)
Intl. J. of Shoulder Surgery     Open Access   (Followers: 7, SJR: 0.611, h-index: 9)
Intl. J. of Trichology     Open Access   (SJR: 0.37, h-index: 10)
Intl. J. of Yoga     Open Access   (Followers: 15)
Intl. J. of Yoga : Philosophy, Psychology and Parapsychology     Open Access   (Followers: 6)
Iranian J. of Nursing and Midwifery Research     Open Access   (Followers: 3)
Iraqi J. of Hematology     Open Access  
J. of Academy of Medical Sciences     Open Access  
J. of Advanced Pharmaceutical Technology & Research     Open Access   (Followers: 4, SJR: 0.427, h-index: 15)
J. of Anaesthesiology Clinical Pharmacology     Open Access   (Followers: 8, SJR: 0.416, h-index: 14)
J. of Applied Hematology     Open Access  
J. of Association of Chest Physicians     Open Access   (Followers: 2)
J. of Basic and Clinical Reproductive Sciences     Open Access   (Followers: 1)
J. of Cancer Research and Therapeutics     Open Access   (Followers: 4, SJR: 0.359, h-index: 21)
J. of Carcinogenesis     Open Access   (Followers: 1, SJR: 1.152, h-index: 26)
J. of Cardiothoracic Trauma     Open Access  
J. of Cardiovascular Disease Research     Open Access   (Followers: 3, SJR: 0.351, h-index: 13)
J. of Cardiovascular Echography     Open Access   (SJR: 0.134, h-index: 2)
J. of Cleft Lip Palate and Craniofacial Anomalies     Open Access   (Followers: 2)
J. of Clinical and Preventive Cardiology     Open Access   (Followers: 1)
J. of Clinical Imaging Science     Open Access   (Followers: 1, SJR: 0.277, h-index: 8)
J. of Clinical Neonatology     Open Access   (Followers: 1)
J. of Clinical Ophthalmology and Research     Open Access   (Followers: 2)
J. of Clinical Sciences     Open Access  
J. of Conservative Dentistry     Open Access   (Followers: 4, SJR: 0.532, h-index: 10)
J. of Craniovertebral Junction and Spine     Open Access   (Followers: 4, SJR: 0.199, h-index: 9)
J. of Current Medical Research and Practice     Open Access  
J. of Current Research in Scientific Medicine     Open Access  
J. of Cutaneous and Aesthetic Surgery     Open Access   (Followers: 1)
J. of Cytology     Open Access   (Followers: 1, SJR: 0.274, h-index: 9)
J. of Dental and Allied Sciences     Open Access   (Followers: 1)
J. of Dental Implants     Open Access   (Followers: 7)
J. of Dental Lasers     Open Access   (Followers: 2)
J. of Dental Research and Review     Open Access   (Followers: 1)
J. of Digestive Endoscopy     Open Access   (Followers: 3)
J. of Dr. NTR University of Health Sciences     Open Access  
J. of Earth, Environment and Health Sciences     Open Access   (Followers: 1)
J. of Education and Ethics in Dentistry     Open Access   (Followers: 5)
J. of Education and Health Promotion     Open Access   (Followers: 5)
J. of Emergencies, Trauma and Shock     Open Access   (Followers: 9, SJR: 0.353, h-index: 14)
J. of Engineering and Technology     Open Access   (Followers: 6)
J. of Experimental and Clinical Anatomy     Open Access   (Followers: 2)
J. of Family and Community Medicine     Open Access   (Followers: 2)
J. of Family Medicine and Primary Care     Open Access   (Followers: 11)

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Journal Cover Journal of Cardiovascular Disease Research
  [SJR: 0.351]   [H-I: 13]   [3 followers]  Follow
    
  This is an Open Access Journal Open Access journal
   ISSN (Print) 0975-3583 - ISSN (Online) 0976-2833
   Published by Medknow Publishers Homepage  [355 journals]
  • Retraction Notice: Severe Abdominal Complaints after Technical Successful
           Endovascular Treatment of Chronic Splanchnic Ischemia

    • Authors: yunus
      Abstract: Journal of Cardiovascular Disease Research,2017,8,4,163.Published:October 2017 Type:Retraction NoticeRetraction Notice: Severe Abdominal Complaints after Technical Successful Endovascular Treatment of Chronic Splanchnic Ischemia
      Claire AJI Leenarts,
      Mark JF Haagmans,
      Lee H Bouwman,
      and Cornelis JJM SikkinkClaire AJI Leenarts1, Mark JF Haagmans1, Lee H Bouwman2, Cornelis JJM Sikkink2 View:PDF (38.03 KB)Click here to download the PDF file. ‹ Swiss Cheese Myocardium: A Diagnostic and Prognostic Sign of HCM by Newer CMR Techniques
      PubDate: Mon, 30 Oct 2017 11:47:55 +000
       
  • Lifestyle Pattern and Hypertension Related Knowledge, Attitude and
           Practices among Diagnosed Patients of Hypertension Attending a Tertiary
           Care Hospital

    • Authors: yunus
      Abstract: Journal of Cardiovascular Disease Research,2017,8,4,108-111.
      DOI :10.5530/jcdr.2017.4.25Published:October 2017 Type:Original ArticleLifestyle Pattern and Hypertension Related Knowledge, Attitude and Practices among Diagnosed Patients of Hypertension Attending a Tertiary Care Hospital
      Lipilekha Patnaik,
      Kalyan Kumar Paul,
      Sumitra Pattnaik,
      and Trilochan SahuLipilekha Patnaik, Kalyan Kumar Paul, Sumitra Pattnaik, Trilochan Sahu Department of Community Medicine IMS & SUM Hospital, S’O’A University, Bhubaneswar, Khordha, Odisha-751003, INDIA. :Context: Hypertension can be controlled by modifying lifestyle related risk factors and generating awareness about these risk factors among hypertensive patients. Aim: To assess the life style pattern, knowledge, attitude and practices related to hypertension among diagnosed patients of hypertension attending a tertiary care hospital. Materials and methods: Across sectional hospital based study was conducted in a tertiary care hospital during May and June 2014.102 diagnosed patients of hypertension attending the Medicine out-patient department were included in the study by convenience sampling. Apre-structured questionnaire was used and data related to demographic profile, history of hypertension, knowledge, attitude and practices regarding hypertension etc. were collected. Data were analysed using Statistical Package for the Social Sciences version 20. Results: Out of 102 participants, 55.9% were males and the mean age was 42.98 + 11.85. The mean systolic blood pressure and diastolic blood pressure was 146.01 + 10.59 and 103.7 + 10.76 respectively. 50% of the patients led a sedentary life & only 13.7% were practicing fitness activities daily. 22.5% were current smokers, 12.7% were passive smokers and 8.8% were currently taking alcohol. About 26.5% patients were not concerned about their increased BP, 5.9% didn’t know any of the risk factors of hypertension &7.8% were unaware of the symptoms of hypertension. Logistic regression showed that occurrence of uncontrolled hypertension is reduced by 0.06 times in patients having satisfactory knowledge. Conclusion: Intervention in the form of lifestyle education during hospital visits will be helpful to increase the awareness about modifiable risk factors, controlling blood pressure and preventing complications among these patients.Keywords:Blood pressure, Body weight, hypertension, Lifestyle., risk factorsView:PDF (231.65 KB)Click here to download the PDF file. ‹ Midodrine and Pyridostigmine; Novelties in Heart Failure Therapy Ischemic Modified Albumin (IMA) as a Novel Marker for Ischemic Heart Disease and Surrogate Marker for Other High Oxidative -Ischemic Conditions ›
      PubDate: Mon, 30 Oct 2017 09:19:29 +000
       
  • Swiss Cheese Myocardium: A Diagnostic and Prognostic Sign of HCM by Newer
           CMR Techniques

    • Authors: yunus
      Abstract: Journal of Cardiovascular Disease Research,2017,8,4,160-162.
      DOI :10.5530/jcdr.2017.4.35Published:October 2017 Type:Case ReportSwiss Cheese Myocardium: A Diagnostic and Prognostic Sign of HCM by Newer CMR Techniques
      Atul Kapoor,
      Harinderpal Singh,
      Aprajita Kapoor,
      and Goldaa MahajanAtul Kapoor1, Harinderpal Singh2, Aprajita Kapoor3, Goldaa Mahajan1 1Consultant Radiologist Advanced Diagnostics, Amritsar, Punjab INDIA.2Director Cardiology Fortis Hospital, Amritsar, Punjab INDIA.3Consultant Advanced Diagnostics, Amritsar, Punjab INDIA. :Cardiac MR(CMR) has an important role in the evaluation of patients of suspected cardiomyopathies and also helps to differentiate between the various types based on the type of late gadolinium enhancements(LGE’s). We describe a characteristic Swiss cheese myocardium appearance in a patient with hypertrophic cardiomyopathy (HCM) using automatic scar analysis algorithm using low < 2SD scale threshold weighting to assess the replacement and interstitial fibrosis along with T1 mapping to quantify it.Keywords:Cardiac MRI, Extracellular volume, Hypertrophic cardiomyopathyView:PDF (284.68 KB)Click here to download the PDF file. ‹ Papaverine on Internal Mammary Artery Flow- Comparitive Study of Intraluminal versus Topical Retraction Notice: Severe Abdominal Complaints after Technical Successful Endovascular Treatment of Chronic Splanchnic Ischemia ›
      PubDate: Tue, 17 Oct 2017 06:34:20 +000
       
  • Papaverine on Internal Mammary Artery Flow- Comparitive Study of
           Intraluminal versus Topical

    • Authors: yunus
      Abstract: Journal of Cardiovascular Disease Research,2017,8,4,157-159.
      DOI :10.5530/jcdr.2017.4.34Published:October 2017 Type:Original ArticlePapaverine on Internal Mammary Artery Flow- Comparitive Study of Intraluminal versus Topical
      Pangi Manish,
      Garg Arun,
      and Sreedhar KumsiPangi Manish, Garg Arun, Sreedhar Kumsi Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bannerghatta Road, Jayanagar 9th Block, Bangalore-560069, Karnataka, INDIA. :Background: Coronary artery bypass grafting (CABG) is the commonest method for surgical revascularisation and Left Internal Mammary artery (LIMA) is the conduit of choice. However it may develop vasospasm during harvesting. Vasodilators like Papaverine have been proposed to relieve vasospasm and hence increase blood flow. However the optimal method of papaverine application is not clear. In this study we have compared the effects of intraluminal versus topical application of papaverine on LIMA flow. Methods: This was prospective randomized controlled trial of 60 patients. They were divided into two groups: group 1 (n=30; intraluminal papaverine application) and group 2 (n=30; topical papaverine application). LIMA was harvested, divided and the blood flow from distal cut end was measured under controlled hemodynamics, before papaverine application and 5 min after papaverine application. Results: In group 1, the mean blood flow was 61.07±3.1 ml/min before papaverine application and 119.6±3.72 ml/min after intraluminal instillation (p value <0.0001). In group 2, it was 60.4±2.24 ml/min before and 72.13±2.56 ml/min after papaverine topical application. The increase in blood flow observed in group 1 was 95.84% versus 19.42% in group 2. Conclusion: In this trial, while papaverine increased blood flow with both methods, it caused a higher rate of increase of blood flow with intraluminal instillation than with topical application.Keywords:CABG, Internal mammary, Intraluminal, OPCAB, Papaverine.View:PDF (115.95 KB)Click here to download the PDF file. ‹ Activation of Cardiac TNF-α in Altered Thyroid State-Induced Cardiometabolic Disorder Swiss Cheese Myocardium: A Diagnostic and Prognostic Sign of HCM by Newer CMR Techniques ›
      PubDate: Tue, 17 Oct 2017 06:30:51 +000
       
  • Activation of Cardiac TNF-α in Altered Thyroid State-Induced
           Cardiometabolic Disorder

    • Authors: yunus
      Abstract: Journal of Cardiovascular Disease Research,2017,8,4,151-156.
      DOI :10.5530/jcdr.2017.4.33Published:October 2017 Type:Original ArticleActivation of Cardiac TNF-α in Altered Thyroid State-Induced Cardiometabolic Disorder
      Ayodeji Folorunsho Ajayi,
      Roland Eghoghosoa Akhigbe,
      and Lydia Oluwatoyin AjayiAyodeji Folorunsho Ajayi1, Roland Eghoghosoa Akhigbe1,2*, Lydia Oluwatoyin Ajayi31Department of Physiology, College of Health Sciences, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, NIGERIA.2State Specialist Hospital, Osogbo, Osun State, NIGERIA.3Department of Biochemistry, Faculty of Basic Medical Sciences, College of Health Sciences, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, NIGERIA. :Background: It is a known fact that altered thyroid state is associated with cardiometabolic disturbances. Raised TNF-α and lipid peroxidation have also been reported to be involved in the pathogenesis of cardiometabolic disorders. Aim: The present study evaluates the effect of dysthyroidism on cardiac TNF-α and lipid peroxidation, and whether the effect is estradiol-dependent. Methods: Male white New Zealand rabbits were randomized into three groups; control, carbimazole- induced hypothyroidism, and levothyroxine-induced hyperthyroidism. Results: Dysthyroidism led to altered glucose metabolism and dyslipidaemia with elevated LDL, TNF-α, and MDA. There was also decreased HDL, GSH, catalase, and 17β-estradiol. Serum electrolytes and hemorheological variables were not significantly affected. Conclusion: These findings demonstrate that dysthyroidism-induced cardiometabolic disturbance is associated with elevated cardiac TNF-α and oxidative stress via an estradiol-dependent mechanism.Keywords:Cardiometabolic Disorder, Dysthyroidism, lipid peroxidation, oxidative stress, TNF-αView:PDF (198.26 KB)Click here to download the PDF file. ‹ Metabolic Syndrome among Apparently Healthy Nigerians with the Harmonized Criteria: Prevalence and Concordance with the (IDF) and Third Report of the (NCEP-ATP III) Criteria Papaverine on Internal Mammary Artery Flow- Comparitive Study of Intraluminal versus Topical ›
      PubDate: Tue, 17 Oct 2017 06:27:22 +000
       
  • Metabolic Syndrome among Apparently Healthy Nigerians with the Harmonized
           Criteria: Prevalence and Concordance with the (IDF) and Third Report of
           the (NCEP-ATP III) Criteria

    • Authors: yunus
      Abstract: Journal of Cardiovascular Disease Research,2018,8,4,145-150.
      DOI :10.5530/jcdr.2017.4.32Published:October 2017 Type:Original ArticleMetabolic Syndrome among Apparently Healthy Nigerians with the Harmonized Criteria: Prevalence and Concordance with the (IDF) and Third Report of the (NCEP-ATP III) Criteria
      TH Raimi,
      O Odusan,
      OA Fasanmade,
      AO Odewabi,
      and AE OhwovorioleTH Raimi1*, O Odusan2, OA Fasanmade3, AO Odewabi4, AE Ohwovoriole31Department of Medicine, Ekiti State University /Ekiti State University Teaching Hospital, Ado-Ekiti, Ekiti State, NIGERIA. 2Department of Medicine, Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, NIGERIA. 3Department of Medicine, Lagos University Teaching Hospital, Idi-Araba, Lagos State, NIGERIA.4Department of Chemical Pathology, Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, NIGERIA. :Background: The prevalence of metabolic syndrome varies by the definition used and the population studied. In order to make comparison among various studies possible, a new criterion which harmonizes the previous definitions was proposed. This study aims to determine the prevalence of metabolic syndrome with the harmonized criteria, and its concordance with the International Diabetes Federation (IDF), and National Cholesterol Education Programme-Adult Treatment Panel (NCEP-ATP III) criteria. Methods: One hundred and two apparently healthy individuals who participated in health screening were evaluated for metabolic syndrome. The blood pressure and anthropometric parameters were measured according to standard protocol, and fasting plasma glucose and lipid profile were determined. Metabolic syndrome was defined using the Harmonized, IDF and ATP III criteria. The agreement among the three diagnostic criteria was determined with kappa statistics. Results: The prevalence of metabolic syndrome was 4.9%, 3.9% and 4.9% with harmonized, IDF, and NCEP-ATP criteria respectively. Compared to the males, the prevalence was greater in females: Males vs Females (harmonized, 2.2% vs 7.0%; IDF, 2.2% vs 5.3%; NCEP-ATP III, 2.2% vs 7.0%). The commonest risk factor in this population was low HDL occurring in 93.0% and 37.8% of females and males respectively, followed by central obesity (50.9% in females, 13.3% in males with harmonized and IDF criteria; 33.3% in females, 4.4% in males with NCEP-ATP criteria), hypertension (12.5% in females, 18.6% in males) and hyperglycaemia (4.2% in females, 0.0% in males) in that order. None of the participants had elevated Triglyceride. There was a substantial concordance between the harmonized and the IDF (k=0.884) as well as the harmonized and NCEP-ATP III (k=1.000) definitions. Conclusion: The prevalence of metabolic syndrome was low in this population. There was a substantial agreement among the three diagnostic criteria.Keywords:Concordance, Diagnostic criteria, metabolic syndrome, Prevalence.View:PDF (160.13 KB)Click here to download the PDF file. ‹ Diagnosis and Identification of...
      PubDate: Tue, 17 Oct 2017 06:24:02 +000
       
  • Diagnosis and Identification of Risk Factors for Heart Disease Patients
           Using Generalized Additive Model and Data Mining Techniques

    • Authors: yunus
      Abstract: Journal of Cardiovascular Disease Research,2017,8,4,137-144.
      DOI :10.5530/jcdr.2017.4.31Published:October 2017 Type:Original ArticleDiagnosis and Identification of Risk Factors for Heart Disease Patients Using Generalized Additive Model and Data Mining Techniques
      Sabyasachi Mukherjee,
      Suman Kapoor,
      and Proloy BanerjeeSabyasachi Mukherjee1, Suman Kapoor2, Proloy Banerjee31Department of Mathematics; NSHM Knowledge Campus, Durgapur-713212, West Bengal , INDIA.2Senior Bio-statistician, Department of Bio-Statistics, Quintiles Clinical Research, Bangalore, Karnataka, INDIA.3Research Scholar, Department of Statistics, Aliah University, Kolkata, West Bengal, INDIA. :Background: Yearly death rate is increasing due to heart disease. Major factors for the increasing death rate due to heart disease are (a) misdiagnosed by the medical doctors or (b) ignorance by the patients. Heart diseases can be described as any kind of disorder which affects the heart. Methods: The dataset of ‘statlog’ from the UCI Machine Learning with 270 patients related to heart disease isused in this article. The dataset comprises attributes of patients diagnosed with heart diseases. The diagnosis was used to confirm whether heart disease is present or absent in the patient. The present article aims to identify the risk factors/variables which influence this diagnosis. Classification is a very important part of the disease diagnosis but it is also relevant to identify the risk factors/variables. Two classification techniques namely Support Vector Machines (SVM), Multi-Layer Perceptrons ensembles (MLPE) and one advanced regression technique,Generalized additive model (GAM) with binomial distribution and‘logit’ link have been introduced for diagnosis and risk factors/variables identification. Results: GAM explains 65% deviance with adjusted R square value 0.70 approximately. Sensitivity analysis has been performed under SVM, which is the best model for this dataset with approximately 85% classification accuracy rate. MLPE gives 82% classification accuracy rate approximately.Maximum heart rate, vessel, old peak, chest pain, thallium scan are the most important factors/variables find through both sensitivity analysis under SVM and GAM. Conclusion: The present article attempt to remove some new information regarding heart disease through probabilistic modeling which may provide better assistance for treatment decision making using the individual patient risk factors and the benefits of a specific treatment. These findings may help the medical practitioners for better medical treatment.Keywords:Data Mining, GAM., heart disease, MLPE, Sensitivity analysis, SVMView:PDF (527.98 KB)Click here to download the PDF file. ‹ Treatment Optimization in Newly Diagnosed Hypertensives using WHO/ISH Cardiovascular Risk Prediction Chart: Findings from ‘Great Indian BP Survey’, Puducherry Metabolic Syndrome among Apparently Healthy Nigerians with the Harmonized Criteria: Prevalence and Concor...
      PubDate: Tue, 17 Oct 2017 06:18:06 +000
       
  • Treatment Optimization in Newly Diagnosed Hypertensives using WHO/ISH
           Cardiovascular Risk Prediction Chart: Findings from ‘Great Indian BP
           Survey’, Puducherry

    • Authors: yunus
      Abstract: Journal of Cardiovascular Disease Research,2017,8,4,133-136.
      DOI :10.5530/jcdr.2017.4.30Published:October 2017 Type:Original ArticleTreatment Optimization in Newly Diagnosed Hypertensives using WHO/ISH Cardiovascular Risk Prediction Chart: Findings from ‘Great Indian BP Survey’, Puducherry
      Santhosh Satheesh,
      Sitanshu Sekhar Kar,
      Kariyarath Cheriyath Premarajan,
      Srikanta Kanungo,
      Mahendra M Reddy,
      Thiruchengodu Ammaiyappan Subathra,
      and Balachander JayaramanSanthosh Satheesh1, Sitanshu Sekhar Kar2, Kariyarath Cheriyath Premarajan2, Srikanta Kanungo2, Mahendra M Reddy3, Thiruchengodu Ammaiyappan Subathra4, Balachander Jayaraman51Department of Cardiology, JIPMER, Puducherry, INDIA.2Department of Preventive and Social Mediine, JIPMER, Puducherry, INDIA.3Department of Community Medicine, Sri Devaraj Urs Medical College, Kolar, Karnataka, INDIA. 4Department of Physiology, JIPMER, Puducherry, INDIA.5Departmrnt of Cardiology, Medical Superintendent, JIPMER Hospital, JIPMER, Puducherry, INDIA. :Background: The ever increasing cost of care for Non Communicable Diseases has led to a profound economic impact on healthcare systems especially in Low and Middle Income (LMIC) countries like India. The documentation of total risk approach as a cost effective tool and as a treatment optimization strategy is less. Objective: To establish the optimization of treatment using WHO/ISH risk prediction charts among the newly diagnosed hypertensives during the ‘Great Indian BP Survey’, Puducherry. Methods: ‘The Great Indian BP Survey’ was conducted during September, 2015 on a single day among the adults (≥18 years) including employees, students, patients and public who visited the campus area of a tertiary care institute in Puducherry, India. A standard protocol was used to measure the blood pressure (BP) by 33 different teams. Cardiovascular disease risk assessment was done for those newly diagnosed hypertensive individuals using WHO/ISH chart without cholesterol version for South East Asian region D (SEAR-D). Results: Of the total 9906 adults screened, mean (SD) age was 35.5 (13.5) years and 5080 (51.3%) were males. Of them, 2714 (27.4%) were found to have raised BP and out of these 1539 (56.7%) became aware about their raised BP status for the first time. Of the newly diagnosed, only 6% (93/1539) had WHO/ISH risk score of ≥20%. Conclusion: The study shows that optimization of treatment using WHO/ISH risk prediction can be a cost-effective approach in LMIC like India.Keywords:hypertension, Newly diagnosed hypertensive, Non Communicable Disease, Treatment optimization, WHOISH Risk Score.View:PDF (149.87 KB)Click here to download the PDF file. ‹ Acute Impact o...
      PubDate: Tue, 17 Oct 2017 05:55:29 +000
       
  • Acute Impact of Balloon Mitral Valvotomy on Left Atrial Functions in
           Mitral Stenosis

    • Authors: yunus
      Abstract: Journal of Cardiovascular Disease Research,2017,8,4,126-132.
      DOI :10.5530/jcdr.2017.4.29Published:October 2017 Type:Original ArticleAcute Impact of Balloon Mitral Valvotomy on Left Atrial Functions in Mitral Stenosis
      Jahangir Rashid Beig,
      Mohd Iqbal Dar,
      Devinder Kumar,
      Ajaz Ahmad Lone,
      Imran Hafeez,
      and Nisar Ahmad TrambooJahangir Rashid Beig, Mohd Iqbal Dar, Devinder Kumar, Ajaz Ahmad Lone, Imran Hafeez, Nisar Ahmad Tramboo Department of Cardiology, SKIMS, Srinagar, Jammu and Kashmir, INDIA. :Background: Rheumatic mitral stenosis (MS) is associated with progressive impairment of left atrial (LA) mechanical functions. This study was conducted to assess the acute impact of Balloon Mitral Valvotomy (BMV) on these functions. Methods: This single centre observational study included 25 patients with severe MS (aged 34.1 ± 7.1 years, with mean mitral valve area of 0.74 ± 0.13 cm²), in sinus rhythm, who underwent successful BMV at our hospital. Phasic LA volumes (Vmax: maximal LA volume, Vmin: minimal LA volume, and Vp: LA volume at the onset of P-wave) were measured by modified Simpson’s method. Parameters of LA reservoir function i.e. LA total emptying fraction (LATEF) and LA expansion index (LAEI); conduit function i.e. LA passive emptying fraction (LAPEF); and pump function i.e. LA active emptying fraction (LAAEF) were calculated from these volumes. All these parameters were evaluated before and 24-48 hours after BMV. Results: Successful BMV led to significant reduction in Vmax (p < 0.001), Vmin (p < 0.001), and Vp (p < 0.001). There was a significant increase in LATEF (p= 0.001) and LAEI (p= 0.002). LAPEF increased insignificantly (p= 0.057), while there was no significant change in LAAEF (p =0.127) after BMV. Conclusion: Successful BMV leads to early improvement in left atrial reservoir and conduit functions, without significantly affecting left atrial pump function. Whether these acute changes translate into long term left atrial reverse remodelling and clinical benefits thereof needs to be established by further studies.Keywords:Balloon mitral valvotomy, Left Atrial Functions, Left Atrial Volume, Mitral stenosis, rheumatic heart diseaseView:PDF (507.37 KB)Click here to download the PDF file. ‹ Gamma Glutamyl Transferase Levels In Patients with Acute Coronary Syndrome: A Cross-Sectional Study Treatment Optimization in Newly Diagnosed Hypertensives using WHO/ISH Cardiovascular Risk Prediction Chart: Findings from ‘Great Indian BP Survey’, Puducherry ›
      PubDate: Tue, 17 Oct 2017 05:49:49 +000
       
  • Gamma Glutamyl Transferase Levels In Patients with Acute Coronary
           Syndrome: A Cross-Sectional Study

    • Authors: yunus
      Abstract: Journal of Cardiovascular Disease Research,2017,8,4,121-125.
      DOI :10.5530/jcdr.2017.4.28Published:October 2017 Type:Original ArticleGamma Glutamyl Transferase Levels In Patients with Acute Coronary Syndrome: A Cross-Sectional Study
      Jain Jyoti,
      Verma Nitin,
      Banait Shashank,
      and Desmukh PradeepJain Jyoti1, Verma Nitin2, Banait Shashank1, Desmukh Pradeep11MGIMS Department of Medicine, Mahatma Gandhi institute of medical sciences, Sevagram, Wardha, Maharashtra, INDIA. 2MGIMS Department of Ophthalmology, Jawaharlal Nehru Medical College, Sawangi Meghe, Wardha, Maharashtra, INDIA. :Background & objectives: Oxidative stress is thought to play a key role in the progression of atherosclerosis. Many studies have identified gamma glutamyltransferase (GGT) as a marker of oxidative stress and its relationship with coronary artery disease (CAD). There is limited data exploring the changes of GGT levels in acute coronary syndrome (ACS). The objective of present study was to assess the prevalence of raised GGT and its correlates in ACS patients. Methods: A cross-sectional study was performed in Intensive cardiac coronary unit of Medicine Department in tertiary care teaching hospital. All consecutive patients of ACS more than 18 years of age were included in this study. ACS was diagnosed on the basis of history, electrocardiogram and biochemical markers. All subjects underwent test for GGT by enzymatic calorimetric method. Magnitude of raised GGT in ACS was expressed in percentage. Unadjusted odds ratio (ORs) and multivariate logistic regression analysis were computed to assess the strength of association between independent variables and dependent variables. P value ≤0.05 was considered as significant. Results: We included 323 study subjects from November 2012 to October 2014. The magnitude of raised GGT among ACS was 41.80%. The magnitude of raised GGT in non ST elevated myocardial infarction (NSTEMI), ST elevated myocardial infarction (STEMI) and unstable angina (UA) was 57.32%, 37.85% and 32.81% respectively. The significant correlate of raised GGT were male sex [OR: 3.58 (95%CI: 1.88- 6.79) P=0.000] and NSTEMI as diagnosis of ACS [OR: 3.32 (95%CI: 1.51-7.30) P=0.003] in the study subjects. Interpretation & Conclusion: Gamma glutamyl transferase activity is increased in subjects with ACS. High levels of serum GGT on admission were associated with the burden of atherosclerosis in patients with ACS.Keywords:Acute coronary syndrome, Coronary artery disease, Gamma glutamyltransferase, oxidative stressView:PDF (378.68 KB)Click here to download the PDF file. ‹ Clinical Outcomes after Triple Vessel Angioplasty in Diabetic Patients with Triple Vessel Coronary Artery Disease Acute Impact of Balloon Mitral Valvotomy on Left Atrial Functions in Mitral Stenosis ›
      PubDate: Tue, 17 Oct 2017 05:42:47 +000
       
 
 
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