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Showing 1 - 200 of 355 Journals sorted alphabetically
Advanced Arab Academy of Audio-Vestibulogy J.     Open Access  
Advances in Human Biology     Open Access   (Followers: 1)
African J. for Infertility and Assisted Conception     Open Access  
African J. of Business Ethics     Open Access   (Followers: 6)
African J. of Medical and Health Sciences     Open Access   (Followers: 1)
African J. of Paediatric Surgery     Open Access   (Followers: 7, SJR: 0.269, h-index: 10)
African J. of Trauma     Open Access  
Ain-Shams J. of Anaesthesiology     Open Access   (Followers: 3)
Al-Azhar Assiut Medical J.     Open Access  
Al-Basar Intl. J. of Ophthalmology     Open Access   (Followers: 1)
Ancient Science of Life     Open Access   (Followers: 6)
Anesthesia : Essays and Researches     Open Access   (Followers: 7)
Annals of African Medicine     Open Access   (Followers: 1, SJR: 0.331, h-index: 15)
Annals of Bioanthropology     Open Access   (Followers: 3)
Annals of Cardiac Anaesthesia     Open Access   (Followers: 13, SJR: 0.408, h-index: 15)
Annals of Indian Academy of Neurology     Open Access   (Followers: 3, SJR: 0.308, h-index: 14)
Annals of Maxillofacial Surgery     Open Access   (Followers: 6)
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 7, SJR: 0.441, h-index: 10)
Annals of Saudi Medicine     Open Access   (SJR: 0.24, h-index: 29)
Annals of Thoracic Medicine     Open Access   (Followers: 4, SJR: 0.388, h-index: 19)
Annals of Tropical Medicine and Public Health     Open Access   (Followers: 15, SJR: 0.148, h-index: 5)
APOS Trends in Orthodontics     Open Access   (Followers: 1)
Arab J. of Interventional Radiology     Open Access  
Archives of Intl. Surgery     Open Access   (Followers: 9)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Archives of Pharmacy Practice     Open Access   (Followers: 5)
Asia Pacific J. of Clinical Trials : Nervous System Diseases     Open Access  
Asia-Pacific J. of Oncology Nursing     Open Access   (Followers: 3)
Asian J. of Andrology     Open Access   (Followers: 1, SJR: 0.879, h-index: 49)
Asian J. of Neurosurgery     Open Access   (Followers: 2)
Asian J. of Oncology     Open Access   (Followers: 1)
Asian J. of Transfusion Science     Open Access   (Followers: 2, SJR: 0.362, h-index: 10)
Astrocyte     Open Access  
Avicenna J. of Medicine     Open Access   (Followers: 1)
AYU : An international quarterly journal of research in Ayurveda     Open Access   (Followers: 6)
Benha Medical J.     Open Access  
BLDE University J. of Health Sciences     Open Access  
Brain Circulation     Open Access  
Bulletin of Faculty of Physical Therapy     Open Access   (Followers: 1)
Cancer Translational Medicine     Open Access   (Followers: 1)
CHRISMED J. of Health and Research     Open Access  
Clinical Dermatology Review     Open Access   (Followers: 1)
Clinical Trials in Degenerative Diseases     Open Access  
Clinical Trials in Orthopedic Disorders     Open Access   (Followers: 1)
Community Acquired Infection     Open Access  
Conservation and Society     Open Access   (Followers: 12, SJR: 0.82, h-index: 12)
Contemporary Clinical Dentistry     Open Access   (Followers: 4)
Current Medical Issues     Open Access   (Followers: 1)
CytoJ.     Open Access   (Followers: 2, SJR: 0.339, h-index: 19)
Delta J. of Ophthalmology     Open Access  
Dental Hypotheses     Open Access   (Followers: 3, SJR: 0.131, h-index: 4)
Dental Research J.     Open Access   (Followers: 9)
Dentistry and Medical Research     Open Access  
Digital Medicine     Open Access  
Drug Development and Therapeutics     Open Access  
Education for Health     Open Access   (Followers: 5, SJR: 0.205, h-index: 22)
Egyptian J. of Bronchology     Open Access  
Egyptian J. of Cardiothoracic Anesthesia     Open Access  
Egyptian J. of Cataract and Refractive Surgery     Open Access   (Followers: 1)
Egyptian J. of Dermatology and Venerology     Open Access   (Followers: 1)
Egyptian J. of Haematology     Open Access  
Egyptian J. of Internal Medicine     Open Access   (Followers: 1)
Egyptian J. of Neurology, Psychiatry and Neurosurgery     Open Access   (Followers: 1, SJR: 0.121, h-index: 3)
Egyptian J. of Obesity, Diabetes and Endocrinology     Open Access  
Egyptian J. of Otolaryngology     Open Access   (Followers: 1)
Egyptian J. of Psychiatry     Open Access   (Followers: 2)
Egyptian J. of Surgery     Open Access   (Followers: 1)
Egyptian Orthopaedic J.     Open Access  
Egyptian Pharmaceutical J.     Open Access  
Egyptian Retina J.     Open Access  
Egyptian Rheumatology and Rehabilitation     Open Access  
Endodontology     Open Access  
Endoscopic Ultrasound     Open Access   (SJR: 0.473, h-index: 8)
Environmental Disease     Open Access  
European J. of Dentistry     Open Access   (Followers: 2, SJR: 0.496, h-index: 11)
European J. of General Dentistry     Open Access   (Followers: 1)
European J. of Prosthodontics     Open Access   (Followers: 2)
European J. of Psychology and Educational Studies     Open Access   (Followers: 7)
Fertility Science and Research     Open Access  
Formosan J. of Surgery     Open Access   (SJR: 0.107, h-index: 5)
Genome Integrity     Open Access   (Followers: 4, SJR: 1.227, h-index: 12)
Global J. of Transfusion Medicine     Open Access   (Followers: 1)
Heart India     Open Access   (Followers: 1)
Heart Views     Open Access   (Followers: 2)
Hepatitis B Annual     Open Access   (Followers: 3)
IJS Short Reports     Open Access  
Indian Anaesthetists Forum     Open Access  
Indian Dermatology Online J.     Open Access   (Followers: 3)
Indian J. of Allergy, Asthma and Immunology     Open Access   (Followers: 1)
Indian J. of Anaesthesia     Open Access   (Followers: 8, SJR: 0.302, h-index: 13)
Indian J. of Burns     Open Access   (Followers: 1)
Indian J. of Cancer     Open Access   (SJR: 0.318, h-index: 26)
Indian J. of Cerebral Palsy     Open Access   (Followers: 1)
Indian J. of Community Medicine     Open Access   (Followers: 2, SJR: 0.618, h-index: 16)
Indian J. of Critical Care Medicine     Open Access   (Followers: 2, SJR: 0.307, h-index: 16)
Indian J. of Dental Research     Open Access   (Followers: 4, SJR: 0.243, h-index: 24)
Indian J. of Dental Sciences     Open Access  
Indian J. of Dentistry     Open Access   (Followers: 1)
Indian J. of Dermatology     Open Access   (Followers: 2, SJR: 0.448, h-index: 16)
Indian J. of Dermatology, Venereology and Leprology     Open Access   (Followers: 3, SJR: 0.563, h-index: 29)
Indian J. of Dermatopathology and Diagnostic Dermatology     Open Access  
Indian J. of Drugs in Dermatology     Open Access   (Followers: 1)
Indian J. of Endocrinology and Metabolism     Open Access   (Followers: 4)
Indian J. of Health Sciences     Open Access   (Followers: 2)
Indian J. of Medical and Paediatric Oncology     Open Access   (SJR: 0.292, h-index: 9)
Indian J. of Medical Microbiology     Open Access   (Followers: 1, SJR: 0.53, h-index: 34)
Indian J. of Medical Research     Open Access   (Followers: 4, SJR: 0.716, h-index: 60)
Indian J. of Medical Sciences     Open Access   (Followers: 2, SJR: 0.207, h-index: 31)
Indian J. of Multidisciplinary Dentistry     Open Access   (Followers: 1)
Indian J. of Nephrology     Open Access   (Followers: 1, SJR: 0.233, h-index: 12)
Indian J. of Nuclear Medicine     Open Access   (Followers: 2, SJR: 0.213, h-index: 5)
Indian J. of Occupational and Environmental Medicine     Open Access   (Followers: 4, SJR: 0.203, h-index: 13)
Indian J. of Ophthalmology     Open Access   (Followers: 5, SJR: 0.536, h-index: 34)
Indian J. of Oral Health and Research     Open Access  
Indian J. of Oral Sciences     Open Access   (Followers: 1)
Indian J. of Orthopaedics     Open Access   (Followers: 9, SJR: 0.393, h-index: 15)
Indian J. of Otology     Open Access   (Followers: 1, SJR: 0.218, h-index: 5)
Indian J. of Paediatric Dermatology     Open Access   (Followers: 2)
Indian J. of Pain     Open Access   (Followers: 1)
Indian J. of Palliative Care     Open Access   (Followers: 5, SJR: 0.35, h-index: 12)
Indian J. of Pathology and Microbiology     Open Access   (Followers: 1, SJR: 0.285, h-index: 22)
Indian J. of Pharmacology     Open Access   (SJR: 0.347, h-index: 44)
Indian J. of Plastic Surgery     Open Access   (Followers: 12, SJR: 0.303, h-index: 13)
Indian J. of Psychiatry     Open Access   (Followers: 3, SJR: 0.496, h-index: 15)
Indian J. of Psychological Medicine     Open Access   (Followers: 1, SJR: 0.344, h-index: 9)
Indian J. of Public Health     Open Access   (Followers: 1, SJR: 0.444, h-index: 17)
Indian J. of Radiology and Imaging     Open Access   (Followers: 4, SJR: 0.253, h-index: 14)
Indian J. of Research in Homoeopathy     Open Access  
Indian J. of Rheumatology     Open Access   (SJR: 0.169, h-index: 7)
Indian J. of Sexually Transmitted Diseases and AIDS     Open Access   (Followers: 2, SJR: 0.313, h-index: 9)
Indian J. of Social Psychiatry     Open Access   (Followers: 2)
Indian J. of Urology     Open Access   (Followers: 3, SJR: 0.366, h-index: 16)
Indian J. of Vascular and Endovascular Surgery     Open Access   (Followers: 2)
Industrial Psychiatry J.     Open Access   (Followers: 2)
Intl. J. of Academic Medicine     Open Access  
Intl. J. of Advanced Medical and Health Research     Open Access  
Intl. J. of Applied and Basic Medical Research     Open Access  
Intl. J. of Clinical and Experimental Physiology     Open Access   (Followers: 1)
Intl. J. of Critical Illness and Injury Science     Open Access   (Followers: 1)
Intl. J. of Educational and Psychological Researches     Open Access   (Followers: 3)
Intl. J. of Environmental Health Engineering     Open Access   (Followers: 1)
Intl. J. of Forensic Odontology     Open Access   (Followers: 1)
Intl. J. of Green Pharmacy     Open Access   (Followers: 4, SJR: 0.229, h-index: 13)
Intl. J. of Health & Allied Sciences     Open Access   (Followers: 3)
Intl. J. of Health System and Disaster Management     Open Access   (Followers: 2)
Intl. J. of Heart Rhythm     Open Access  
Intl. J. of Medicine and Public Health     Open Access   (Followers: 7)
Intl. J. of Mycobacteriology     Open Access   (SJR: 0.239, h-index: 4)
Intl. J. of Noncommunicable Diseases     Open Access  
Intl. J. of Nutrition, Pharmacology, Neurological Diseases     Open Access   (Followers: 4)
Intl. J. of Oral Health Sciences     Open Access   (Followers: 1)
Intl. J. of Orthodontic Rehabilitation     Open Access  
Intl. J. of Pedodontic Rehabilitation     Open Access  
Intl. J. of Pharmaceutical Investigation     Open Access   (Followers: 1)
Intl. J. of Preventive Medicine     Open Access   (Followers: 1, SJR: 0.523, h-index: 15)
Intl. J. of Shoulder Surgery     Open Access   (Followers: 7, SJR: 0.611, h-index: 9)
Intl. J. of Trichology     Open Access   (SJR: 0.37, h-index: 10)
Intl. J. of Yoga     Open Access   (Followers: 15)
Intl. J. of Yoga : Philosophy, Psychology and Parapsychology     Open Access   (Followers: 6)
Iranian J. of Nursing and Midwifery Research     Open Access   (Followers: 2)
Iraqi J. of Hematology     Open Access  
J. of Academy of Medical Sciences     Open Access  
J. of Advanced Pharmaceutical Technology & Research     Open Access   (Followers: 4, SJR: 0.427, h-index: 15)
J. of Anaesthesiology Clinical Pharmacology     Open Access   (Followers: 8, SJR: 0.416, h-index: 14)
J. of Applied Hematology     Open Access  
J. of Association of Chest Physicians     Open Access   (Followers: 2)
J. of Basic and Clinical Reproductive Sciences     Open Access   (Followers: 1)
J. of Cancer Research and Therapeutics     Open Access   (Followers: 4, SJR: 0.359, h-index: 21)
J. of Carcinogenesis     Open Access   (Followers: 1, SJR: 1.152, h-index: 26)
J. of Cardiothoracic Trauma     Open Access  
J. of Cardiovascular Disease Research     Open Access   (Followers: 3, SJR: 0.351, h-index: 13)
J. of Cardiovascular Echography     Open Access   (SJR: 0.134, h-index: 2)
J. of Cleft Lip Palate and Craniofacial Anomalies     Open Access   (Followers: 2)
J. of Clinical and Preventive Cardiology     Open Access   (Followers: 1)
J. of Clinical Imaging Science     Open Access   (Followers: 1, SJR: 0.277, h-index: 8)
J. of Clinical Neonatology     Open Access   (Followers: 1)
J. of Clinical Ophthalmology and Research     Open Access   (Followers: 2)
J. of Clinical Sciences     Open Access  
J. of Conservative Dentistry     Open Access   (Followers: 4, SJR: 0.532, h-index: 10)
J. of Craniovertebral Junction and Spine     Open Access   (Followers: 4, SJR: 0.199, h-index: 9)
J. of Current Medical Research and Practice     Open Access  
J. of Current Research in Scientific Medicine     Open Access  
J. of Cutaneous and Aesthetic Surgery     Open Access   (Followers: 1)
J. of Cytology     Open Access   (Followers: 1, SJR: 0.274, h-index: 9)
J. of Dental and Allied Sciences     Open Access   (Followers: 1)
J. of Dental Implants     Open Access   (Followers: 7)
J. of Dental Lasers     Open Access   (Followers: 2)
J. of Dental Research and Review     Open Access   (Followers: 1)
J. of Digestive Endoscopy     Open Access   (Followers: 3)
J. of Dr. NTR University of Health Sciences     Open Access  
J. of Earth, Environment and Health Sciences     Open Access   (Followers: 1)
J. of Education and Ethics in Dentistry     Open Access   (Followers: 5)
J. of Education and Health Promotion     Open Access   (Followers: 5)
J. of Emergencies, Trauma and Shock     Open Access   (Followers: 9, SJR: 0.353, h-index: 14)
J. of Engineering and Technology     Open Access   (Followers: 6)
J. of Experimental and Clinical Anatomy     Open Access   (Followers: 2)
J. of Family and Community Medicine     Open Access   (Followers: 2)
J. of Family Medicine and Primary Care     Open Access   (Followers: 10)

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Journal Cover Journal of Cardiovascular Disease Research
  [SJR: 0.351]   [H-I: 13]   [3 followers]  Follow
    
  This is an Open Access Journal Open Access journal
   ISSN (Print) 0975-3583 - ISSN (Online) 0976-2833
   Published by Medknow Publishers Homepage  [355 journals]
  • Gamma Glutamyl Transferase Levels in Patients with Acute Coronary
           Syndrome: A Cross-Sectional Study

    • Authors: yunus
      Abstract: Journal of Cardiovascular Disease Research,2017,8,3,96-100.
      DOI :10.5530/jcdr.2017.3.22Published:July 2017Type:Original ArticleGamma Glutamyl Transferase Levels in Patients with Acute Coronary Syndrome: A Cross-Sectional Study
      Jain Jyoti,
      Verma Nitin,
      Banait Shashank,
      and Desmukh PradeepJain Jyoti1*, Verma Nitin2, Banait Shashank1, Desmukh Pradeep1 1Department of Medicine, Mahatma Gandhi institute of Medical Sciences, Sevagram, Wardha, Maharashtra, INDIA.2Department of Ophthalmology, Jawaharlal Nehru Medical College, Sawangi Meghe, Wardha, Maharashtra, INDIA.:Background & Objectives: Oxidative stress is thought to play a key role in the progression of atherosclerosis. Many studies have identified gamma glutamyltransferase (GGT) as a marker of oxidative stress and its relationship with coronary artery disease (CAD). There is limited data exploring the changes of GGT levels in acute coronary syndrome (ACS). The objective of present study was to assess the prevalence of raised GGT and its correlates in ACS patients. Methods: A cross-sectional study was performed in Intensive cardiac coronary unit of Medicine Department in tertiary care teaching hospital. All consecutive patients of ACS more than 18 years of age were included in this study. ACS was diagnosed on the basis of history, electrocardiogram and biochemical markers. All subjects underwent test for GGT by enzymatic calorimetric method. Magnitude of raised GGT in ACS was expressed in percentage. Unadjusted odds ratio (ORs) and multivariate logistic regression analysis were computed to assess the strength of association between independent variables and dependent variables. P value ≤0.05 was considered as significant. Results: We included 323 study subjects from November 2012 to October 2014. The magnitude of raised GGT among ACS was 41.80%. The magnitude of raised GGT in non ST elevated myocardial infarction (NSTEMI), ST elevated myocardial infarction (STEMI) and unstable angina (UA) was 57.32%, 37.85% and 32.81% respectively. The significant correlate of raised GGT were male sex [OR: 3.58 (95%CI: 1.88- 6.79) P=0.000] and NSTEMI as diagnosis of ACS [OR: 3.32 (95%CI: 1.51-7.30) P=0.003] in the study subjects. Interpretation and Conclusion: Gamma glutamyl transferase activity is increased in subjects with ACS. High levels of serum GGT on admission were associated with the burden of atherosclerosis in patients with ACS.Keywords:Acute coronary syndrome, Coronary artery disease, Gamma glutamyltransferase, Oxidative Stress.View:PDF (358.42 KB)Full TextClick here to download the PDF file. ‹ Assessment of Risk of Metabolic Syndrome and Cardio Vascular Diseases among Medical Students in India Unusual Vascular Manifestations of Noonan Syndrome ›
      PubDate: Wed, 02 Aug 2017 10:34:35 +000
       
  • Unusual Vascular Manifestations of Noonan Syndrome

    • Authors: yunus
      Abstract: Journal of Cardiovascular Disease Research,2017,8,3,101-103.
      DOI :10.5530/jcdr.2017.3.23Published:July 2017Type:Case Report Unusual Vascular Manifestations of Noonan Syndrome
      Jeremy Burt,
      Ashley Ramirez,
      Joseph Limback,
      Edward Derrick,
      Ali Agha,
      and Laura VarichJeremy Burt, Ashley Ramirez, Joseph Limback*, Edward Derrick, Ali Agha, Laura Varich Department of Radiology, RSF/Florida Hospital, Orlando, FL, USA.:Noonan syndrome is a relatively common autosomal dominant disorder. We present a patient with Noonan syndrome and multiple cardiac and vascular manifestations, some of which are unusual and rarely reported. Further research is necessary to determine whether these defects are truly secondary to Noonan syndrome or possibly another underlying congenital abnormality.Keywords:Coronary Artery Aneurysm, Noonan Syndrome, Solitary Coronary Artery.View:PDF (441.76 KB)Full TextClick here to download the PDF file. ‹ Gamma Glutamyl Transferase Levels in Patients with Acute Coronary Syndrome: A Cross-Sectional Study
      PubDate: Tue, 04 Jul 2017 11:09:01 +000
       
  • Assessment of Risk of Metabolic Syndrome and Cardio Vascular Diseases
           among Medical Students in India

    • Authors: yunus
      Abstract: Journal of Cardiovascular Disease Research,2017,8,3,89-95.
      DOI :10.5530/jcdr.2017.3.21Published:July 2017Type:Original ArticleAssessment of Risk of Metabolic Syndrome and Cardio Vascular Diseases among Medical Students in India
      Nitin Joseph,
      Karthika Chettuvatti,
      Harsh Yadav,
      Hariharan Bharadwaj,
      and Shashidhar M KotianNitin Joseph1, Karthika Chettuvatti2, Harsh Yadav2, Hariharan Bharadwaj2, Shashidhar M Kotian31M.D (Community Medicine), Post Graduate Diploma in Family Medicine, Associate Professor, Department of Community Medicine, Kasturba Medical College, Manipal University, Mangalore, INDIA.2MBBS Graduate, Kasturba Medical College, Manipal University, Mangalore, INDIA.3Selection Grade Lecturer, Department of Community Medicine, Kasturba Medical College, Manipal University, Light House Hill Road, Mangalore, INDIA.:Background: Medical students are vulnerable to various lifestyle disorders due to improper diet, physical activity and inadequate sleep. Aims: To assess the risk status of components of metabolic syndrome and cardiovascular diseases among medical students. Methods: Information was collected using a standard self-administered questionnaire. Blood pressure, waist circumference, height and weight of students were measured using standard procedures. Fasting blood sample was taken for plasma glucose, lipid profile, cortisol levels and thyroid hormone assays. Results: Eighty-eight participants with mean age 21.9 ± 1.1 years took part in this study. Thirty-one (35.2%) participants reported fried food consumption every day. Majority of the participants 35(39.8%) reported moderate exercise less than once a week. Most participants 83 (94.3%) had sleep duration of ≤8 hours at night. Various components of metabolic syndrome like waist circumference (WC), triglyceride (TG) levels, high density lipoprotein (HDL) levels, blood pressure (BP) values and fasting blood glucose (FBG) levels were abnormal in 36 (40.9%), 2 (2.3%), 39 (44.3%), 21 (23.9%) and 7 (7.9%) participants respectively. Obesity was present among 33 (37.5%) students. Positive correlation between body mass index (BMI) with WC (p<0.001) and TG (p=0.011) and negative correlation between BMI and HDL levels (p=0.008) was observed. There was also a positive correlation between WC with SBP (p=0.006) and with DBP (p=0.049) values. One or more risk factors of metabolic syndrome was present among 67 (76.1%) participants. It was present among greater proportion of participants with sleep duration of ≤8 hours at night (p=0.05). Medium to high risk of cardiovascular diseases was observed among 30 (34.1%) participants. Conclusion: High proportions of students are vulnerable to develop metabolic syndrome and cardio vascular diseases in this setting. BMI assessment can be used as best predictor to identify the high-risk groups. Improvement in diet, physical activity and adequate sleep duration is required for risk mitigation.Keywords:Body mass index., cardiovascular diseases, Medical Students, metabolic syndrome, risk factorsView:PDF (282.11 KB)Full Text
      PubDate: Tue, 04 Jul 2017 10:54:14 +000
       
  • Study of Metabolic Syndrome and Its Components Among Kurnool District
           Population of Andhra Pradesh with Different Ethnic Backgrounds

    • Authors: yunus
      Abstract: Journal of Cardiovascular Disease Research,2017,8,3,83-88.
      DOI :10.5530/jcdr.2017.3.20Published:July 2017Type:Original ArticleStudy of Metabolic Syndrome and Its Components Among Kurnool District Population of Andhra Pradesh with Different Ethnic Backgrounds
      Pandit Vinodh Bandela,
      Nilima Nandakumar Dongre,
      Jeevan Gangadhar Ambekar,
      Kedam Durga Prasad,
      and Basavaraj B DevaranavadagiPandit Vinodh Bandela1*, Nilima Nandakumar Dongre2, Jeevan Gangadhar Ambekar3, Kedam Durga Prasad4, Basavaraj B Devaranavadagi51Research Scholar, Department of Biochemistry, BLDEU’S, Shri B. M. Patil Medical College, Hospital and Research Centre, Vijayapur, Karnataka, INDIA.2Associate Professor, Department of Biochemistry, BLDEU’S, Shri B. M. Patil Medical College, Hospital and Research Centre, Vijayapur, Karnataka, INDIA.3Professor, Department of Biochemistry, BLDEU’S, Shri B. M. Patil Medical College, Vijayapur, Karnataka, INDIA.4Professor, Department of Biochemistry, Santhiram Medical College, Nandyal, Andhra Pradesh, INDIA5Professor and HOD, Department of Biochemistry, BLDEU’S, Shri B. M. Patil Medical College, Vijayapur, Karnataka, INDIA.:Background: There is a constant increase in the preponderance of cardiovascular diseases in India. The recent scientific evidences have shown that if you do not detect and treat the metabolic syndrome patients at an early stage, it may proceed to cardiovascular disease. A scientific data on pattern of metabolic syndrome components of a population is very essential to formulate the preventive and treatment modalities among them. Aim: To explore the prevalence of metabolic syndrome and its components among Kurnool district population of Andhra Pradesh with different ethnic background. Method: A total of 1032 (344 subjects in each group) participants of 20-60 years of age group were analyzed for MetS. A modified NCEP ATP III criterion was applied for this. From each group 20 subjects were analyzed for fasting serum insulin and HOMA-IR randomly. Results: Overall prevalence of metabolic syndrome was found to 31.97%. It was almost equally prevalent among men (32.82%) and women (30.87%). Urban population (42.15%) were found to be highly inflicted by metabolic syndrome than rural (31.97%) and tribal (21.80%). Decreased HDL (78.87%) followed by increased waist circumference (57.84%) and hypertriglyceridemia (31.78%) were found to be the preceding risk factors of Mets in all the groups. The lipid estimates were not in correlation with insulin resistance (by HOMA IR) in rural population. Tribal women were found to be having a slightly higher mean waist circumference (86.45cm) compared to rural women (85.87cm). The behavioural cardiovascular risk factors like smoking alcohol consumption decreased circadian physical activity were high in rural and tribal population compared to urban population. Whereas other physiological cardiovascular risk factors like family history of hypertension and diabetes of rural population were in concordance to urban population. Conclusion: Metabolic syndrome prevalence is very high in Kurnool district population. Mets components are highly prevalent among the individuals with low WC (Waist Circumference) and BMI (Body Mass Index). This warrants the need to implement preventive strategies for Mets among the population of Kurnool district. The future projects has to be formulated with an aim to find out the genetic factors behind this scenario.Keywords:Adults, Insulin resistance, Kurnool District, Population., Prevalence of Metabolic Syndrome, Rural, Tribal, UrbanView:...
      PubDate: Tue, 04 Jul 2017 10:44:57 +000
       
  • Association of Polymorphisms in CYP2C19 with the Efficacy of Clopidogrel
           Therapy in South Indian Patients Undergoing Percutaneous Coronary
           Intervention

    • Authors: yunus
      Abstract: Journal of Cardiovascular Disease Research,2017,8,3,78-82.
      DOI :10.5530/jcdr.2017.3.19Published:July 2017Type:Original ArticleAssociation of Polymorphisms in CYP2C19 with the Efficacy of Clopidogrel Therapy in South Indian Patients Undergoing Percutaneous Coronary Intervention
      Nuthalapati Rama Kumari,
      Ravella Keerthika,
      Murki Naveen Kumar,
      Jahangeer Basha,
      Konda Kumaraswami,
      Indukuri Bhaskara Raju,
      and Vijay Kumar KutalaNuthalapati Rama Kumari1, Ravella Keerthika1, Murki Naveen Kumar1, Jahangeer Basha1, Konda Kumaraswami2, Indukuri Bhaskara Raju3, Vijay Kumar Kutala21Departments of Cardiology, Nizam’s Institute of Medical Sciences, Hyderabad, INDIA2Clinical Pharmacology and Therapeutics, Nizam’s Institute of Medical Sciences, Hyderabad, INDIA3Department of Surgery, Gandhi Medical College, Secunderabad, Hyderabad, INDIA:Background: The dual antiplatelet therapy (DAPT) with aspirin and clopidogrel has been considered as the standard of care in the setting of acute coronary syndrome (ACS) and percutaneous coronary intervention (PCI). Recent evidence supports a role of loss-of-function (LOF) variants in the CYP2C19 as a determinant of clopidogrel response. Carriers of the CYP2C19*2 LOF allele has found to have the reduced pharmacodynamic response to clopidogrel and worse clinical outcome as compared with non-carriers in Asian countries including Indian population. However, it is unknown whether the time course of the antiplatelet effects of clopidogrel differs according to CYP2C19 genotype in South Indian patients with ACS. Methods: We assessed the platelet reactivity in the early and late phases of ACS according to CYP2C19 genotypes. Eighty six consecutive in-patients who were admitted with ACS at our center were enrolled in the study. The determination of platelet aggregation was done by using a platelet aggregometer and genetic analysis was done by PCR-RFLP method. Results: The numbers of patients carrying the CYP2C19*1/*1 (extensive metabolizer, EM), *1/*2 (Intermediate metabolizer, IM), *2/*2 (poor metabolizer PM), genotypes were 22 (30.9%), 37 (52.1%), 12 (16.9%), respectively. Time course of platelet aggregation from baseline to the late phase among the 3 genotypes indicate that there was statistically significant at 30th day of treatment (p=0.004) between wild versus hetero and homozygous variant alleles. The percentage of patients shifted to prasugrel from clopidogrel due to non-response were 4 (8%), 11(29%), 6 (50%) in wild, heterozygous and homozygous variant alleles. In homozygous group, we found 4 out of 6 patients developed acute stent thrombosis within one week of PCI. Conclusion: We observed that the CYP2C19*2 and CYP2C19*1/*2 are the major determinants of clopidogrel efficacy. Acute stent thrombosis was observed in patients carrying CYP2C19*2 variant allele.Keywords:Acute coronary syndrome, Antiplatelet therapy, Clopidogrel, Percutanous coronary intervention, Pharmacogenetics.View:PDF (645.78 KB)Full Text
      PubDate: Tue, 04 Jul 2017 10:39:30 +000
       
  • Laughter-Induced Syncope: Literature Review

    • Authors: yunus
      Abstract: Journal of Cardiovascular Disease Research,2017,8,3,66-71.
      DOI :10.5530/jcdr.2017.3.17Published:July 2017Type:Review ArticleLaughter-Induced Syncope: Literature Review
      Sylvia Biso,
      Supakanya Wongrakpanich,
      Akanksha Agrawal,
      Sujani Yadlapati,
      Marina Kishlyansky Do,
      Mary Rodriguez-Ziccardi,
      and Toni Anne De VeneciaSylvia Biso, Supakanya Wongrakpanich, Akanksha Agrawal, Sujani Yadlapati, Marina Kishlyansky Do, Mary Rodriguez Ziccardi, Toni Anne De Venecia Department of Medicine, Einstein Medical Center, 5401 Old York Road, Suite 363, Philadelphia, USA.:Syncope is a common and pervasive medical problem. The etiology of 30-40% of syncope remains unknown. Laughterinduced syncope is a rare subtype of vasovagal syncope that is not well understood. With this literature review we hope to elucidate the epidemiology, symptomatology, pathophysiology, diagnosis and therapeutic options of laughter-induced syncope. Greater awareness of laughter-induced syncope may better direct clinical investigations and improve patient care.Keywords:Gelastic syncope, Laughter-induced syncope, Sitcom syncope, Situational syncope, Syncope.View:PDF (134.79 KB)Full TextClick here to download the PDF file. ‹ J. Cardiovasc. Dis. Res., 8(3), 2017 Stenting of Aortic Coarctation: Immediate and Intermediate Follow-up Results ›
      PubDate: Tue, 04 Jul 2017 10:31:53 +000
       
  • Stenting of Aortic Coarctation: Immediate and Intermediate Follow-up
           Results

    • Authors: yunus
      Abstract: Journal of Cardiovascular Disease Research,2017,8,3,72-77.
      DOI :10.5530/jcdr.2017.2.18Published:June 2017Type:Original ArticleStenting of Aortic Coarctation: Immediate and Intermediate Follow-up Results
      Vijaykumar Janakaloti Ramachandra Reddy,
      Huliyurdurga Srinivasasetty Natraj Setty,
      Babu Reddy Jayarangnath,
      and Cholenahalli Nanjappa ManjunathVijaykumar Janakaloti Ramachandra Reddy, Huliyurdurga Srinivasasetty Natraj Setty, Babu Reddy, Jayarangnath, Cholenahalli Nanjappa Manjunath Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bengaluru, Karnataka, INDIA.:Background: Coarctation of the aorta occurs in about 6% to 8%of patients with congenital heart disease Surgery, balloon dilatation, and stent implantation have all proven effective in the treatment of moderate or severe obstruction. Objective: Assess the initial and intermediate term results of stent implantation in all age groups with both native and recurrent coarctation of aorta. Patients and design: A total of 23 patients (14 [65.4%] males and 9 [34.6%] females) with congenital COA who had undergone aortic stenting angioplasty were recruited. Nineteen (82.6%) of these patients had native COA and four (17.38%) had recurrent COA.(one after previous coarctation stenting with stent fracture and three after balloon dilatation). Clinical data was collected at baseline, before discharge, and at follow-up and included upper and lower extremity systolic/diastolic blood pressure, as well as the need for antihypertensive medication , and echocardiographic data like COA gradient, associated lesions and concentric LVH. During procedure pre and post cath gradient across coarctation segment taken, along with assessment for any complications. Results: Immediately after stent implantation the peak systolic cath gradient (mean (SD)) fell from 61.6 (13.3) to 8.1 (3.6) mm Hg (p = 0.00). The diameter of the stenotic lesion increased from 4.58 (0.5) mm to 14.8 (1.3) mm (p < 0.05). There were no deaths or procedure related complications. Only one patient (4.34%) developed early complications. Acute procedural success was 91%. During the follow-up of one month 3 (13%) of the patients had re-stenosis. At a mean follow up of 14 months, 4 cases of re-coarctation were identified echocardiographically and 43.47% had chronic systemic hypertension, requiring drug therapy. Conclusions: Stent implantation for the treatment of coarctation of the aorta appears to have very low morbidity and mortality, and good intermediate term results. Endovascular stenting could be an effective and safe method, even in all age group of patients with native and recurrent COA.Keywords:Coarctation of aorta, Coarctationstenting, Congenital heart disease., Intermediate, RecoarctationView:PDF (210.03 KB)Full TextClick here to download the PDF file. ‹ Laughter-Induced Syncope: Literature Review Association of Poly...
      PubDate: Sat, 01 Jul 2017 11:44:37 +000
       
 
 
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