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Publisher: Medknow Publishers   (Total: 356 journals)

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Showing 1 - 200 of 356 Journals sorted alphabetically
Advanced Arab Academy of Audio-Vestibulogy J.     Open Access  
Advances in Human Biology     Open Access  
African J. for Infertility and Assisted Conception     Open Access  
African J. of Business Ethics     Open Access   (Followers: 7)
African J. of Medical and Health Sciences     Open Access  
African J. of Paediatric Surgery     Open Access   (Followers: 7, SJR: 0.269, h-index: 10)
African J. of Trauma     Open Access  
Ain-Shams J. of Anaesthesiology     Open Access   (Followers: 3)
Al-Azhar Assiut Medical J.     Open Access  
Al-Basar Intl. J. of Ophthalmology     Open Access  
Ancient Science of Life     Open Access   (Followers: 6)
Anesthesia : Essays and Researches     Open Access   (Followers: 7)
Annals of African Medicine     Open Access   (Followers: 1, SJR: 0.331, h-index: 15)
Annals of Bioanthropology     Open Access   (Followers: 2)
Annals of Cardiac Anaesthesia     Open Access   (Followers: 12, SJR: 0.408, h-index: 15)
Annals of Indian Academy of Neurology     Open Access   (Followers: 3, SJR: 0.308, h-index: 14)
Annals of Maxillofacial Surgery     Open Access   (Followers: 6)
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 5, SJR: 0.441, h-index: 10)
Annals of Saudi Medicine     Open Access   (SJR: 0.24, h-index: 29)
Annals of Thoracic Medicine     Open Access   (Followers: 4, SJR: 0.388, h-index: 19)
Annals of Tropical Medicine and Public Health     Open Access   (Followers: 15, SJR: 0.148, h-index: 5)
APOS Trends in Orthodontics     Open Access   (Followers: 1)
Arab J. of Interventional Radiology     Open Access  
Archives of Intl. Surgery     Open Access   (Followers: 9)
Archives of Medicine and Health Sciences     Open Access   (Followers: 2)
Archives of Pharmacy Practice     Open Access   (Followers: 4)
Asia Pacific J. of Clinical Trials : Nervous System Diseases     Open Access  
Asia-Pacific J. of Oncology Nursing     Open Access   (Followers: 3)
Asian J. of Andrology     Open Access   (Followers: 1, SJR: 0.879, h-index: 49)
Asian J. of Neurosurgery     Open Access   (Followers: 2)
Asian J. of Oncology     Open Access   (Followers: 1)
Asian J. of Transfusion Science     Open Access   (Followers: 1, SJR: 0.362, h-index: 10)
Astrocyte     Open Access  
Avicenna J. of Medicine     Open Access   (Followers: 1)
AYU : An international quarterly journal of research in Ayurveda     Open Access   (Followers: 6)
Benha Medical J.     Open Access  
BLDE University J. of Health Sciences     Open Access  
Brain Circulation     Open Access   (Followers: 1)
Bulletin of Faculty of Physical Therapy     Open Access  
Cancer Translational Medicine     Open Access   (Followers: 1)
CHRISMED J. of Health and Research     Open Access  
Clinical Dermatology Review     Open Access  
Clinical Trials in Degenerative Diseases     Open Access  
Clinical Trials in Orthopedic Disorders     Open Access  
Community Acquired Infection     Open Access  
Conservation and Society     Open Access   (Followers: 10, SJR: 0.82, h-index: 12)
Contemporary Clinical Dentistry     Open Access   (Followers: 4)
Current Medical Issues     Open Access  
CytoJ.     Open Access   (Followers: 2, SJR: 0.339, h-index: 19)
Delta J. of Ophthalmology     Open Access  
Dental Hypotheses     Open Access   (Followers: 3, SJR: 0.131, h-index: 4)
Dental Research J.     Open Access   (Followers: 9)
Dentistry and Medical Research     Open Access  
Digital Medicine     Open Access  
Drug Development and Therapeutics     Open Access  
Education for Health     Open Access   (Followers: 4, SJR: 0.205, h-index: 22)
Egyptian J. of Bronchology     Open Access  
Egyptian J. of Cardiothoracic Anesthesia     Open Access  
Egyptian J. of Cataract and Refractive Surgery     Open Access   (Followers: 1)
Egyptian J. of Dermatology and Venerology     Open Access  
Egyptian J. of Haematology     Open Access  
Egyptian J. of Internal Medicine     Open Access  
Egyptian J. of Neurology, Psychiatry and Neurosurgery     Open Access   (Followers: 1, SJR: 0.121, h-index: 3)
Egyptian J. of Obesity, Diabetes and Endocrinology     Open Access  
Egyptian J. of Otolaryngology     Open Access  
Egyptian J. of Psychiatry     Open Access   (Followers: 2)
Egyptian J. of Surgery     Open Access   (Followers: 1)
Egyptian Orthopaedic J.     Open Access  
Egyptian Pharmaceutical J.     Open Access  
Egyptian Retina J.     Open Access  
Egyptian Rheumatology and Rehabilitation     Open Access  
Endodontology     Open Access  
Endoscopic Ultrasound     Open Access   (SJR: 0.473, h-index: 8)
Environmental Disease     Open Access  
European J. of Dentistry     Open Access   (Followers: 2, SJR: 0.496, h-index: 11)
European J. of General Dentistry     Open Access   (Followers: 1)
European J. of Prosthodontics     Open Access   (Followers: 2)
European J. of Psychology and Educational Studies     Open Access   (Followers: 6)
Fertility Science and Research     Open Access  
Formosan J. of Surgery     Open Access   (SJR: 0.107, h-index: 5)
Genome Integrity     Open Access   (Followers: 4, SJR: 1.227, h-index: 12)
Global J. of Transfusion Medicine     Open Access  
Heart India     Open Access  
Heart Views     Open Access  
Hepatitis B Annual     Open Access   (Followers: 3)
IJS Short Reports     Open Access  
Indian Anaesthetists Forum     Open Access  
Indian Dermatology Online J.     Open Access   (Followers: 2)
Indian J. of Allergy, Asthma and Immunology     Open Access   (Followers: 1)
Indian J. of Anaesthesia     Open Access   (Followers: 7, SJR: 0.302, h-index: 13)
Indian J. of Burns     Open Access   (Followers: 1)
Indian J. of Cancer     Open Access   (SJR: 0.318, h-index: 26)
Indian J. of Cerebral Palsy     Open Access  
Indian J. of Community Medicine     Open Access   (Followers: 2, SJR: 0.618, h-index: 16)
Indian J. of Critical Care Medicine     Open Access   (Followers: 1, SJR: 0.307, h-index: 16)
Indian J. of Dental Research     Open Access   (Followers: 4, SJR: 0.243, h-index: 24)
Indian J. of Dental Sciences     Open Access  
Indian J. of Dentistry     Open Access   (Followers: 1)
Indian J. of Dermatology     Open Access   (Followers: 2, SJR: 0.448, h-index: 16)
Indian J. of Dermatology, Venereology and Leprology     Open Access   (Followers: 2, SJR: 0.563, h-index: 29)
Indian J. of Dermatopathology and Diagnostic Dermatology     Open Access  
Indian J. of Drugs in Dermatology     Open Access  
Indian J. of Endocrinology and Metabolism     Open Access   (Followers: 4)
Indian J. of Health Sciences     Open Access   (Followers: 1)
Indian J. of Medical and Paediatric Oncology     Open Access   (SJR: 0.292, h-index: 9)
Indian J. of Medical Microbiology     Open Access   (Followers: 1, SJR: 0.53, h-index: 34)
Indian J. of Medical Research     Open Access   (Followers: 4, SJR: 0.716, h-index: 60)
Indian J. of Medical Sciences     Open Access   (Followers: 2, SJR: 0.207, h-index: 31)
Indian J. of Multidisciplinary Dentistry     Open Access   (Followers: 1)
Indian J. of Nephrology     Open Access   (Followers: 1, SJR: 0.233, h-index: 12)
Indian J. of Nuclear Medicine     Open Access   (Followers: 2, SJR: 0.213, h-index: 5)
Indian J. of Occupational and Environmental Medicine     Open Access   (Followers: 4, SJR: 0.203, h-index: 13)
Indian J. of Ophthalmology     Open Access   (Followers: 4, SJR: 0.536, h-index: 34)
Indian J. of Oral Health and Research     Open Access  
Indian J. of Oral Sciences     Open Access   (Followers: 1)
Indian J. of Orthopaedics     Open Access   (Followers: 9, SJR: 0.393, h-index: 15)
Indian J. of Otology     Open Access   (Followers: 1, SJR: 0.218, h-index: 5)
Indian J. of Paediatric Dermatology     Open Access   (Followers: 1)
Indian J. of Pain     Open Access   (Followers: 1)
Indian J. of Palliative Care     Open Access   (Followers: 5, SJR: 0.35, h-index: 12)
Indian J. of Pathology and Microbiology     Open Access   (Followers: 1, SJR: 0.285, h-index: 22)
Indian J. of Pharmacology     Open Access   (SJR: 0.347, h-index: 44)
Indian J. of Plastic Surgery     Open Access   (Followers: 12, SJR: 0.303, h-index: 13)
Indian J. of Psychiatry     Open Access   (Followers: 3, SJR: 0.496, h-index: 15)
Indian J. of Psychological Medicine     Open Access   (Followers: 1, SJR: 0.344, h-index: 9)
Indian J. of Public Health     Open Access   (Followers: 1, SJR: 0.444, h-index: 17)
Indian J. of Radiology and Imaging     Open Access   (Followers: 4, SJR: 0.253, h-index: 14)
Indian J. of Research in Homoeopathy     Open Access  
Indian J. of Rheumatology     Open Access   (SJR: 0.169, h-index: 7)
Indian J. of Sexually Transmitted Diseases and AIDS     Open Access   (Followers: 2, SJR: 0.313, h-index: 9)
Indian J. of Social Psychiatry     Open Access   (Followers: 2)
Indian J. of Urology     Open Access   (Followers: 3, SJR: 0.366, h-index: 16)
Indian J. of Vascular and Endovascular Surgery     Open Access   (Followers: 2)
Industrial Psychiatry J.     Open Access   (Followers: 2)
Intl. J. of Academic Medicine     Open Access  
Intl. J. of Advanced Medical and Health Research     Open Access  
Intl. J. of Applied and Basic Medical Research     Open Access  
Intl. J. of Clinical and Experimental Physiology     Open Access   (Followers: 1)
Intl. J. of Critical Illness and Injury Science     Open Access  
Intl. J. of Educational and Psychological Researches     Open Access   (Followers: 2)
Intl. J. of Environmental Health Engineering     Open Access   (Followers: 1)
Intl. J. of Forensic Odontology     Open Access   (Followers: 1)
Intl. J. of Green Pharmacy     Open Access   (Followers: 4, SJR: 0.229, h-index: 13)
Intl. J. of Health & Allied Sciences     Open Access   (Followers: 1)
Intl. J. of Health System and Disaster Management     Open Access   (Followers: 2)
Intl. J. of Heart Rhythm     Open Access  
Intl. J. of Medicine and Public Health     Open Access   (Followers: 7)
Intl. J. of Mycobacteriology     Open Access   (SJR: 0.239, h-index: 4)
Intl. J. of Noncommunicable Diseases     Open Access  
Intl. J. of Nutrition, Pharmacology, Neurological Diseases     Open Access   (Followers: 4)
Intl. J. of Oral Health Sciences     Open Access   (Followers: 1)
Intl. J. of Orthodontic Rehabilitation     Open Access  
Intl. J. of Pedodontic Rehabilitation     Open Access  
Intl. J. of Pharmaceutical Investigation     Open Access   (Followers: 1)
Intl. J. of Preventive Medicine     Open Access   (Followers: 1, SJR: 0.523, h-index: 15)
Intl. J. of Shoulder Surgery     Open Access   (Followers: 6, SJR: 0.611, h-index: 9)
Intl. J. of Trichology     Open Access   (SJR: 0.37, h-index: 10)
Intl. J. of Yoga     Open Access   (Followers: 15)
Intl. J. of Yoga : Philosophy, Psychology and Parapsychology     Open Access   (Followers: 6)
Iranian J. of Nursing and Midwifery Research     Open Access   (Followers: 2)
Iraqi J. of Hematology     Open Access  
J. of Academy of Medical Sciences     Open Access  
J. of Advanced Pharmaceutical Technology & Research     Open Access   (Followers: 4, SJR: 0.427, h-index: 15)
J. of Anaesthesiology Clinical Pharmacology     Open Access   (Followers: 8, SJR: 0.416, h-index: 14)
J. of Applied Hematology     Open Access  
J. of Association of Chest Physicians     Open Access   (Followers: 2)
J. of Basic and Clinical Reproductive Sciences     Open Access   (Followers: 1)
J. of Cancer Research and Therapeutics     Open Access   (Followers: 4, SJR: 0.359, h-index: 21)
J. of Carcinogenesis     Open Access   (Followers: 1, SJR: 1.152, h-index: 26)
J. of Cardiothoracic Trauma     Open Access  
J. of Cardiovascular Disease Research     Open Access   (Followers: 3, SJR: 0.351, h-index: 13)
J. of Cardiovascular Echography     Open Access   (SJR: 0.134, h-index: 2)
J. of Cleft Lip Palate and Craniofacial Anomalies     Open Access   (Followers: 2)
J. of Clinical and Preventive Cardiology     Open Access  
J. of Clinical Imaging Science     Open Access   (Followers: 1, SJR: 0.277, h-index: 8)
J. of Clinical Neonatology     Open Access   (Followers: 1)
J. of Clinical Ophthalmology and Research     Open Access   (Followers: 1)
J. of Clinical Sciences     Open Access  
J. of Conservative Dentistry     Open Access   (Followers: 4, SJR: 0.532, h-index: 10)
J. of Craniovertebral Junction and Spine     Open Access   (Followers: 4, SJR: 0.199, h-index: 9)
J. of Current Medical Research and Practice     Open Access  
J. of Current Research in Scientific Medicine     Open Access  
J. of Cutaneous and Aesthetic Surgery     Open Access   (Followers: 1)
J. of Cytology     Open Access   (Followers: 1, SJR: 0.274, h-index: 9)
J. of Dental and Allied Sciences     Open Access   (Followers: 1)
J. of Dental Implants     Open Access   (Followers: 7)
J. of Dental Lasers     Open Access   (Followers: 2)
J. of Dental Research and Review     Open Access   (Followers: 1)
J. of Digestive Endoscopy     Open Access   (Followers: 3)
J. of Dr. NTR University of Health Sciences     Open Access  
J. of Earth, Environment and Health Sciences     Open Access   (Followers: 1)
J. of Education and Ethics in Dentistry     Open Access   (Followers: 5)
J. of Education and Health Promotion     Open Access   (Followers: 5)
J. of Emergencies, Trauma and Shock     Open Access   (Followers: 8, SJR: 0.353, h-index: 14)
J. of Engineering and Technology     Open Access   (Followers: 6)
J. of Experimental and Clinical Anatomy     Open Access   (Followers: 2)
J. of Family and Community Medicine     Open Access  
J. of Family Medicine and Primary Care     Open Access   (Followers: 8)

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Journal Cover Indian Journal of Urology
  [SJR: 0.366]   [H-I: 16]   [3 followers]  Follow
    
  This is an Open Access Journal Open Access journal
   ISSN (Print) 0970-1591
   Published by Medknow Publishers Homepage  [356 journals]
  • Revisiting prostate cancer: Can we separate the wheat from the
           chaff?

    • Authors: Arabind Panda
      Pages: 97 - 98
      Abstract: Arabind Panda
      Indian Journal of Urology 2017 33(2):97-98

      Citation: Indian Journal of Urology 2017 33(2):97-98
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/iju.IJU_95_17
      Issue No: Vol. 33, No. 2 (2017)
       
  • What's inside

    • Authors: Arabind Panda
      Pages: 99 - 100
      Abstract: Arabind Panda
      Indian Journal of Urology 2017 33(2):99-100

      Citation: Indian Journal of Urology 2017 33(2):99-100
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/iju.IJU_96_17
      Issue No: Vol. 33, No. 2 (2017)
       
  • Roundup

    • Authors: Santosh Kumar
      Pages: 101 - 103
      Abstract: Santosh Kumar
      Indian Journal of Urology 2017 33(2):101-103

      Citation: Indian Journal of Urology 2017 33(2):101-103
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/iju.IJU_86_17
      Issue No: Vol. 33, No. 2 (2017)
       
  • Bladder cancer: 2017 and beyond

    • Authors: Ashish M Kamat
      Pages: 104 - 105
      Abstract: Ashish M Kamat
      Indian Journal of Urology 2017 33(2):104-105

      Citation: Indian Journal of Urology 2017 33(2):104-105
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/0970-1591.203419
      Issue No: Vol. 33, No. 2 (2017)
       
  • Advances in surgical management of muscle invasive bladder cancer

    • Authors: Janet Baack Kukreja, Jay B Shah
      Pages: 106 - 110
      Abstract: Janet Baack Kukreja, Jay B Shah
      Indian Journal of Urology 2017 33(2):106-110
      Introduction: Bladder cancer remains a disease of the elderly with relatively few advances that have improved survival over the last 20 years. Radical cystectomy (RC) has long remained the principal treatment for muscle-invasive bladder cancer (MIBC).Methods: A literature search of PubMed was performed. The content was reviewed for continuity with the topic of surgical advances in MIBC. Articles and society guidelines were included in this review.Results: Despite the associated morbidity, even in the elderly, RC is still a reasonable option. Modifications during RC may have a positive or negative impact on survival and quality of life. The extent of pelvic lymph node dissection is one such factor which may positively impact survival outcomes. In addition, preservation of pelvic organs, robotic surgery and the adoption of enhanced recovery after surgery principles continues to improve the postoperative recovery and quality of life in RC patients.Conclusion: There are some ongoing studies in many of these areas, but overall the new advances in MIBC may improve patient quality and quantity of life. The advances in surgical treatment of MIBC are important and the focus of the review here.
      Citation: Indian Journal of Urology 2017 33(2):106-110
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/0970-1591.203416
      Issue No: Vol. 33, No. 2 (2017)
       
  • Where are we with bladder preservation for muscle-invasive bladder cancer
           in 2017?

    • Authors: Woodson Wade Smelser, Marcus A Austenfeld, Jeffrey Maxwell Holzbeierlein, Eugene Kang Lee
      Pages: 111 - 117
      Abstract: Woodson Wade Smelser, Marcus A Austenfeld, Jeffrey Maxwell Holzbeierlein, Eugene Kang Lee
      Indian Journal of Urology 2017 33(2):111-117
      Introduction: In 2017, neoadjuvant, cisplatin-based chemotherapy followed by radical cystectomy (RC) is considered the gold standard therapy for muscle-invasive bladder based on randomized controlled trials. Across all tumor stages, this approach has been associated with the highest rates of disease-specific survival. However, RC is one of the most challenging procedures performed by urologic surgeons and carries with it significant risks of complications, hospital readmission, and even a small risk of mortality, in addition to lifestyle changes that can have long-term effects on well-being. For these reasons, bladder-sparing approaches are utilized in some highly selected patients. We reviewed the most recent evidence for bladder-sparing modalities for muscle-invasive urothelial bladder cancer and summarize those findings in this review article.Methods: We performed a PubMed literature review utilizing the key words “bladder preservation,” “trimodal therapy,” “muscle-invasive bladder cancer,” and “partial cystectomy” written in English, dating back to 1990. We excluded case reports.Results: Our search yielded more than 2000 articles which we screened. Some articles were then rejected due to inappropriate topic. In addition, we reviewed the most recent American Urological Association, National Comprehensive Cancer Network (NCCN), and European guidelines on muscle-invasive bladder cancer. We identified fifty relevant articles which are summarized in this text. In some rare instances, recommendations are based on expert opinion.Conclusions: Bladder preservation is often considered for quality of life considerations or in the setting of multiple medical comorbidities, and this remains oncologically appropriate even in 2016 in highly selected patients with muscle-invasive urothelial carcinoma of the bladder.
      Citation: Indian Journal of Urology 2017 33(2):111-117
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/iju.IJU_279_16
      Issue No: Vol. 33, No. 2 (2017)
       
  • Systemic therapy in bladder cancer

    • Authors: Ian G Pinto
      Pages: 118 - 126
      Abstract: Ian G Pinto
      Indian Journal of Urology 2017 33(2):118-126
      Systemic chemotherapy is essential for the management of muscle-invasive bladder cancer (MIBC) and metastatic bladder cancer (BCa). Neoadjuvant chemotherapy is key to the management of MIBC with many cisplatin-based regimens. Adjuvant chemotherapy may be considered for selected patients who did not receive neoadjuvant therapy. Systemic chemotherapy with radiotherapy is a critical component of a trimodal bladder-preserving approach and is superior to radiotherapy alone. Cisplatin-based chemotherapy has been the mainstay for metastatic BCa. Immunotherapy in the form of checkpoint inhibitors is a promising new drug for the treatment of BCa. Molecular characterization of each individual BCa is likely to lead to a target-directed therapeutic revolution.
      Citation: Indian Journal of Urology 2017 33(2):118-126
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/iju.IJU_294_16
      Issue No: Vol. 33, No. 2 (2017)
       
  • Bladder cancer: Micro RNAs as biomolecules for prognostication and
           surveillance

    • Authors: Nilay Mitash, Swasti Tiwari, Shalini Agnihotri, Anil Mandhani
      Pages: 127 - 133
      Abstract: Nilay Mitash, Swasti Tiwari, Shalini Agnihotri, Anil Mandhani
      Indian Journal of Urology 2017 33(2):127-133
      Introduction: Bladder cancer (BC) has varied clinical behavior in terms of recurrence and progression. Current pathological characteristics are insufficient to prognosticate the outcome of a given treatment. Cellular metabolic regulatory molecules, such as micro RNA (miRNA), could be a potential biomarker to prognosticate the treatment outcomes.Materials and Methods: PubMed and Google Scholar databases were searched for publications from 1990 to 2016, related to miRNA biogenesis, its function, and role in the pathogenesis of bladder as well as other cancers. Articles were searched using MeSH terms micrornas, micrornas AND neoplasm, and micrornas AND urinary bladder neoplasm. Out of the 108 publications reviewed 75 references were selected based on the clinical relevance. Articles were reviewed to assess the role of miRNA in various cancers and those in BC as a diagnostic or therapeutic tool.Results: More than 35 miRNAs were found to be associated with different pathways of cellular dedifferentiation, proliferation, and progression of BC as well as other cancers. A normal looking mucosa may show molecular changes preceding phenotypic changes in the form of varied expression of miR-129, miR-200a, and miR-205. miR-214, miR-99a, and miR-125b have been shown to be potential urinary biomarkers of BC. miRNAs could act as a repressor for protein molecule functioning or activator of different pathways to be used as a therapeutic target too.Conclusions: Despite certain limitations, such as instability, rapid plasma clearance, and targeting antagonist proteins of cellular metabolic pathways, miRNAs have potential to be studied as a biomarker or a therapeutic target for BC.
      Citation: Indian Journal of Urology 2017 33(2):127-133
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/0970-1591.203412
      Issue No: Vol. 33, No. 2 (2017)
       
  • Multiparametric magnetic resonance imaging-transrectal ultrasound fusion
           prostate biopsy: A prospective, single centre study

    • Authors: Somendra Bansal, Narmada P Gupta, Rajiv Yadav, Rakesh Khera, Kulbir Ahlawat, Dheeraj Gautam, Rajesh Ahlawat, Gagan Gautam
      Pages: 134 - 139
      Abstract: Somendra Bansal, Narmada P Gupta, Rajiv Yadav, Rakesh Khera, Kulbir Ahlawat, Dheeraj Gautam, Rajesh Ahlawat, Gagan Gautam
      Indian Journal of Urology 2017 33(2):134-139
      Introduction: Transrectal rectal ultrasound (TRUS)-guided systematic biopsy is the gold standard for diagnosis of prostate cancer. However, systematic biopsy has high false-negative rate and often misses anteriorly located tumors. Magnetic resonance imaging (MRI)-TRUS fusion biopsy can potentially improve cancer detection by better visualization and targeting of cancer focus. We evaluated the role of fusion biopsy in detection of prostate cancer and the association of prostate imaging reporting and data system (PI-RADS) score for predicting cancer risk and its aggression.Methods: Ninety-six consecutive men with suspected prostate cancer underwent MRI-TRUS fusion-targeted biopsy of suspicious lesions and standard 12 core biopsy from May 2014 to July 2015 in our institution. All patients underwent 3.0 T multiparametric MRI before biopsy. mp-MRI included T2W, DWI, DCE and MRS sequences to identify lesions suspicious for prostate cancer. Suspected lesions were scored according to PI-RADS scoring system. Comparison of cancer detection between standard 12 core biopsy and MRI-TRUS fusion biopsy was done. Detection of prostate cancer was primary end point of this study.Results: Mean age was 64.4 years and median prostate-specific antigen was 8.6 ng/ml. Prostate cancer was detected in 57 patients (59.3%). Of these 57 patients, 8 patients (14%) were detected by standard 12 core biopsy only, 7 patients (12.3%) with MRI-TRUS fusion biopsy only, and 42 patients (73.7%) by both techniques. Of the 7 patients, detected with MRI-TRUS fusion biopsy alone, 6 patients (85.7%) had Gleason ≥7 disease. Prostate cancer was detected on either standard 12 core biopsy or MRI-TRUS fusion biopsy in 0%, 42.8%, 74%, and 89.3% patients of suspicious lesions of highest PI-RADS score 2, 3, 4, and 5, respectively.Conclusions: MRI-TRUS fusion prostate biopsy improves cancer detection rate when combined with standard 12 cores biopsy and detects more intermediate or high-grade prostate cancer (Gleason ≥7). With increasing PI-RADS score, there is an increase chance of detection of cancer as well as its aggressiveness.
      Citation: Indian Journal of Urology 2017 33(2):134-139
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/0970-1591.203414
      Issue No: Vol. 33, No. 2 (2017)
       
  • Perioperative complications and postoperative outcomes of partial
           nephrectomy for renal cell carcinoma: Does indication matter?

    • Authors: Vivek Venkatramani, Santosh Kumar, J Chandrasingh, Antony Devasia, Nitin S Kekre
      Pages: 140 - 143
      Abstract: Vivek Venkatramani, Santosh Kumar, J Chandrasingh, Antony Devasia, Nitin S Kekre
      Indian Journal of Urology 2017 33(2):140-143
      Introduction: The aim of the study was to determine whether perioperative complications and postoperative outcomes varied with the indication of partial nephrectomy (PN).Materials and Methods: We reviewed data of 184 consecutive PN for suspected renal cell carcinoma operated between January 2004 and December 2013. Complications using the Clavien-Dindo classification were compared between surgeries for absolute indications (chronic renal failure, bilateral tumors, or solitary kidney), those for relative indications (comorbid illnesses with the potential to affect renal function) and elective indications (patients without risk factors). Complex tumors were defined as size >7 cm, multiple, hilar, and endophytic tumors.Results: Patients with an absolute indication had larger tumors (P = 0.001) and tumors of a higher pathological T-stage (P = 0.03). Minor complications (Clavien 1 and 2) occurred in 25.4% patients in the elective arm versus over 40% in the other arms (P = 0.049). Major complications (Clavien 3+) were less common in the elective arm (3.2% cases vs. 12.7% in the relative arm and 13.8% in the absolute arm) with a trend to significance (P = 0.09). On multivariate analysis, absolute indication (odds ratio [OR] = 2.4, P = 0.04) and surgery for a complex renal mass (OR = 2.5 times, P = 0.03) remained significant predictors of minor complications. Major complications were more common in the relative (OR = 5.5, P = 0.057) and absolute indication arm (OR = 5.231, P = 0.051) with a trend toward significance.Conclusions: Elective indication was associated with fewer complications than PN for relative or absolute indications.
      Citation: Indian Journal of Urology 2017 33(2):140-143
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/0970-1591.203420
      Issue No: Vol. 33, No. 2 (2017)
       
  • Comparison of sterile water irrigation versus intravesical mitomycin C in
           preventing recurrence of nonmuscle invasive bladder cancer after
           transurethral resection

    • Authors: Priyank Bijalwan, Ginil Kumar Pooleri, Appu Thomas
      Pages: 144 - 148
      Abstract: Priyank Bijalwan, Ginil Kumar Pooleri, Appu Thomas
      Indian Journal of Urology 2017 33(2):144-148
      Introduction: Early recurrence of nonmuscle invasive bladder cancer (NMIBC) following transurethral resection (TUR) remains relatively high. An immediate single instillation of mitomycin C (MMC) reduces the recurrence rates in the first 2 years but has not shown benefits in tumor progression or overall survival. Distilled water irrigation has shown to delay tumor recurrence by osmolysis of tumor cells. There are only limited clinical studies comparing the efficacy of MMC with continuous sterile water irrigation (CSWI) in preventing the recurrence of NMIBC after TUR in clinical setting.Materials and Methods: A prospective, randomized, open-label, two-arm, single-center, pilot study was conducted between December 2013 and September 2015 at a tertiary-care center in South India. Patients were randomized into CSWI group (n = 19) or single dose intravesical MMC group (n = 17) following TUR for NMIBC and analyzed. All patients were followed up with flexible cystoscopy and urine cytology at 3 months interval for 1 year. Recurrence-free rate was estimated as the primary criterion for outcome analysis.Results: At the end of 12 months, recurrence-free rates for MMC and CSWI groups were 47.1% and 52.6%, respectively. The mean recurrence-free interval for MMC and CSWI groups were 10.9 months and 9.8 months, respectively. The difference in recurrence-free rate or recurrence-free interval between two groups was statistically nonsignificant. Further, the complications in MMC group were significantly higher than that in CSWI group (P = 0.047).Conclusions: Continuous bladder irrigation with sterile water after TUR may be comparable to immediate single dose intravesical MMC in preventing tumor recurrence in NMIBC.
      Citation: Indian Journal of Urology 2017 33(2):144-148
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/iju.IJU_371_16
      Issue No: Vol. 33, No. 2 (2017)
       
  • Fosfomycin susceptibility among multidrug-resistant, extended-spectrum
           beta-lactamase-producing, carbapenem-resistant uropathogens

    • Authors: Sayantan Banerjee, Mallika Sengupta, Tanoy Kumer Sarker
      Pages: 149 - 154
      Abstract: Sayantan Banerjee, Mallika Sengupta, Tanoy Kumer Sarker
      Indian Journal of Urology 2017 33(2):149-154
      Introduction: Urinary tract infection (UTI) is one of the most common infectious diseases. With the emergence of multidrug resistance (MDR), therapeutic options for treatment of UTIs are becoming limited. Fosfomycin has emerged as a novel oral therapeutic option with bactericidal activity against the MDR uropathogens. We evaluated the susceptibility pattern of uropathogens to this antibiotic.Methods: A prospective study was conducted for 6 months in a tertiary care hospital in Eastern India to evaluate whether the common uropathogens were susceptible to fosfomycin. Identification of organisms causing significant bacteriuria was done by conventional biochemical and VITEK 2 Compact System™. Antimicrobial susceptibility testing was performed against these pathogens by Kirby-Bauer disc diffusion method. Minimum inhibitory concentrations were measured for certain drugs by E-strips and VITEK 2 Compact System.Results: A total of 2229 urine samples were referred for culture during the study period, which yielded 356 significant bacterial isolates. Among these isolates, 64.78% were extended-spectrum beta-lactamases producers, 15.97% were carbapenem-resistant Enterobacteriaceae, and 42.7% isolates were found to be MDR Enterobacteriaceae (MDRE). However, 95.18% of the total isolates and 95.93% of MDRE were found to be susceptible to fosfomycin.Conclusion: The common uropathogens, including MDR isolates, show high in vitro susceptibility to fosfomycin, which therefore has the potential to emerge as a promising alternative oral agent for outpatient therapy of UTIs.
      Citation: Indian Journal of Urology 2017 33(2):149-154
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/iju.IJU_285_16
      Issue No: Vol. 33, No. 2 (2017)
       
  • A novel composite two-stage urethroplasty for complex penile strictures: A
           multicenter experience

    • Authors: Pankaj M Joshi, Guido Barbagli, Vikram Batra, Sandesh Surana, Atef Hamouda, Salvatore Sansalone, Dimitris Costi, Massimo Lazzeri, Craig Hunter, Devang J Desai, Fabio Castiglione, Sanjay B Kulkarni
      Pages: 155 - 158
      Abstract: Pankaj M Joshi, Guido Barbagli, Vikram Batra, Sandesh Surana, Atef Hamouda, Salvatore Sansalone, Dimitris Costi, Massimo Lazzeri, Craig Hunter, Devang J Desai, Fabio Castiglione, Sanjay B Kulkarni
      Indian Journal of Urology 2017 33(2):155-158
      Introduction: Complex penile strictures are usually repaired using a two-stage urethroplasty. Buccal mucosal graft (BMG) placed in the first stage can have a significant contraction rate, which may require a subsequent revision surgery. We describe a composite two-stage penile urethroplasty using BMG for patients of complex penile strictures who have some salvageable urethral plate.Methods: Within a multi-institutional cohort, 82 patients underwent a two-stage urethroplasty for complex stricture of the penile urethra. Of these 42 patients who underwent our composite two-stage penile urethroplasty using BMG implanted at the second-stage were included. Patients with genital lichen sclerosus or incomplete clinical records were excluded from this study. The primary outcome of the study was to evaluate stricture-free success rate.Results: Of total 42, 4 patients were lost to follow-up. 42% of stricture etiology was failed hypospadias repair. Mean stricture length was 4.5 cm (range 3–8 cm). Seventeen (44.7%) patients had undergone the previous urethroplasty. At a median follow-up of 44 months, of 38 patients, 34 (89.5%) were successful, and 4 (10.5%) had a recurrence. No patient required revision surgery before the second-stage and required redo buccal graft harvesting for subsequent urethroplasty.Conclusions: The composite two-stage technique in repairing complex penile urethral strictures is a valid and reproducible surgical treatment for complex penile stricture and it may reduce the rate of contraction of the transplanted BMG.
      Citation: Indian Journal of Urology 2017 33(2):155-158
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/0970-1591.203426
      Issue No: Vol. 33, No. 2 (2017)
       
  • Development and validation of Incontinence - Activity Participation Scale
           for spinal cord injury

    • Authors: Priya Walia, Jaskirat Kaur
      Pages: 159 - 164
      Abstract: Priya Walia, Jaskirat Kaur
      Indian Journal of Urology 2017 33(2):159-164
      Introduction: We aimed to develop and validate an Incontinence - Activity Participation Scale (I-APS) for measurement of activity limitation and participation restriction due to bladder problems in spinal cord injury (SCI).Materials and Methods: The process of development was initiated by formation of open-ended questions after thorough review of literature which were then administered to SCI participants, caretakers, and professionals working with SCI. Items were generated based on their responses and initial draft of scale was formulated. This initial draft of the scale containing 77 items was then administered to 56 SCI participants for reduction of items using factor analysis, and a prefinal version of the scale was obtained containing thirty items only. Content validity and face validity was then established.Results: The I-APS is both health professional and self-administered questionnaire including two domains: Activities of daily living and occupation with 16 items having a content validity of 0.84. The overall internal consistency reliability was 0.86.Conclusion: The I-APS is a valid, comprehensive instrument that measures the activity limitation and participation restrictions due to bladder problems in SCI.
      Citation: Indian Journal of Urology 2017 33(2):159-164
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/0970-1591.203413
      Issue No: Vol. 33, No. 2 (2017)
       
  • Silicate urolithiasis in a paediatric patient

    • Authors: Rajarajan Pichandi, Sathish Kumar Motilal Raamya
      Pages: 165 - 166
      Abstract: Rajarajan Pichandi, Sathish Kumar Motilal Raamya
      Indian Journal of Urology 2017 33(2):165-166
      Silicate urolithiasis is rare in humans (0.2%) but common in herbivorous animals. We report a previously unreported instance in India where a pediatric patient with renal pelvic calculus who underwent percutaneous nephrolithotomy was found to have silicate urolithiasis on stone analysis. Retrospective analysis did not reveal any risk factors associated with silicate stone formation.
      Citation: Indian Journal of Urology 2017 33(2):165-166
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/iju.IJU_183_16
      Issue No: Vol. 33, No. 2 (2017)
       
  • Primary intrarenal yolk sac tumor

    • Authors: Narasimhan Ragavan, P Dholakia Kunal, S Annapurneshwari
      Pages: 167 - 168
      Abstract: Narasimhan Ragavan, P Dholakia Kunal, S Annapurneshwari
      Indian Journal of Urology 2017 33(2):167-168
      Extragonadal germ cell tumors (EGGCTs) usually are not coexistent with a gonadal tumor, hence in a way, are primary and are rare. The origin of primary EGGCT is still a matter of debate. Herewith, we report a patient with primary intrarenal yolk sac tumor in a 43-year-old man. The purpose of this report is to add a rare tumor to the differential diagnosis of renal neoplasms.
      Citation: Indian Journal of Urology 2017 33(2):167-168
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/0970-1591.203410
      Issue No: Vol. 33, No. 2 (2017)
       
  • The negative pyelogram in urinary obstruction

    • Authors: Onkar Singh, Partho Mukherjee, Antony Devasia
      Pages: 169 - 170
      Abstract: Onkar Singh, Partho Mukherjee, Antony Devasia
      Indian Journal of Urology 2017 33(2):169-170
      A case of chronic ureteral obstruction secondary to radiation-related ureteral stricture producing a classic “negative pyelogram” on intravenous urography is presented.
      Citation: Indian Journal of Urology 2017 33(2):169-170
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/iju.IJU_395_16
      Issue No: Vol. 33, No. 2 (2017)
       
  • A single left renal vein draining into the common iliac vein

    • Authors: Awad Bakhit Kaabneh, Sizeph Edward Haddad, Feras Ahmad Hammouri, Abdalla Yosef Omari, Mohammad K Abdadayem
      Pages: 171 - 172
      Abstract: Awad Bakhit Kaabneh, Sizeph Edward Haddad, Feras Ahmad Hammouri, Abdalla Yosef Omari, Mohammad K Abdadayem
      Indian Journal of Urology 2017 33(2):171-172
      Several variations of the anatomy of the left renal vein have been reported. Rare variants are frequently overlooked in the preoperative assessment but can lead to complications during surgery. We describe a kidney donor with a rare anomaly of a single main left renal vein draining into the left common iliac vein.
      Citation: Indian Journal of Urology 2017 33(2):171-172
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/iju.IJU_356_16
      Issue No: Vol. 33, No. 2 (2017)
       
  • “Flying-saucer in the pelvis” sign: An equivalent of
           “pelvic Mickey mouse” sign

    • Authors: Onkar Singh, Nitin Sudhakar Kekre
      Pages: 173 - 174
      Abstract: Onkar Singh, Nitin Sudhakar Kekre
      Indian Journal of Urology 2017 33(2):173-174
      Isolated bilateral inguinal vesical hernia with urinary bladder as the only content is very rare. “Pelvic Mickey mouse” sign is a radiological sign described classically for bilateral inguinal vesical hernia on transverse axial imaging. Another imaging finding of a “Flying-saucer in the pelvis” sign seen on conventional intravenous urography is being presented.
      Citation: Indian Journal of Urology 2017 33(2):173-174
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/0970-1591.203423
      Issue No: Vol. 33, No. 2 (2017)
       
  • Reporting and publishing research in the biomedical sciences

    • Authors: Sanjay Sinha
      Pages: 175 - 175
      Abstract: Sanjay Sinha
      Indian Journal of Urology 2017 33(2):175-175

      Citation: Indian Journal of Urology 2017 33(2):175-175
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/iju.IJU_72_17
      Issue No: Vol. 33, No. 2 (2017)
       
  • Reply to: Biochemical failure after radical prostatectomy in
           intermediate-risk group men increases with the number of risk factors

    • Authors: Sohrab Arora
      Pages: 176 - 177
      Abstract: Sohrab Arora
      Indian Journal of Urology 2017 33(2):176-177

      Citation: Indian Journal of Urology 2017 33(2):176-177
      PubDate: Thu,30 Mar 2017
      DOI: 10.4103/iju.IJU_71_17
      Issue No: Vol. 33, No. 2 (2017)
       
 
 
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