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Publisher: Medknow Publishers   (Total: 355 journals)

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Showing 1 - 200 of 355 Journals sorted alphabetically
Advanced Arab Academy of Audio-Vestibulogy J.     Open Access  
Advances in Human Biology     Open Access   (Followers: 1)
African J. for Infertility and Assisted Conception     Open Access  
African J. of Business Ethics     Open Access   (Followers: 6)
African J. of Medical and Health Sciences     Open Access   (Followers: 2)
African J. of Paediatric Surgery     Open Access   (Followers: 7, SJR: 0.269, h-index: 10)
African J. of Trauma     Open Access  
Ain-Shams J. of Anaesthesiology     Open Access   (Followers: 3)
Al-Azhar Assiut Medical J.     Open Access  
Al-Basar Intl. J. of Ophthalmology     Open Access   (Followers: 1)
Ancient Science of Life     Open Access   (Followers: 6)
Anesthesia : Essays and Researches     Open Access   (Followers: 8)
Annals of African Medicine     Open Access   (Followers: 1, SJR: 0.331, h-index: 15)
Annals of Bioanthropology     Open Access   (Followers: 3)
Annals of Cardiac Anaesthesia     Open Access   (Followers: 14, SJR: 0.408, h-index: 15)
Annals of Indian Academy of Neurology     Open Access   (Followers: 3, SJR: 0.308, h-index: 14)
Annals of Maxillofacial Surgery     Open Access   (Followers: 6)
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 7, SJR: 0.441, h-index: 10)
Annals of Saudi Medicine     Open Access   (SJR: 0.24, h-index: 29)
Annals of Thoracic Medicine     Open Access   (Followers: 4, SJR: 0.388, h-index: 19)
Annals of Tropical Medicine and Public Health     Open Access   (Followers: 15, SJR: 0.148, h-index: 5)
APOS Trends in Orthodontics     Open Access   (Followers: 1)
Arab J. of Interventional Radiology     Open Access  
Archives of Intl. Surgery     Open Access   (Followers: 9)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Archives of Pharmacy Practice     Open Access   (Followers: 6)
Asia Pacific J. of Clinical Trials : Nervous System Diseases     Open Access  
Asia-Pacific J. of Oncology Nursing     Open Access   (Followers: 3)
Asian J. of Andrology     Open Access   (Followers: 1, SJR: 0.879, h-index: 49)
Asian J. of Neurosurgery     Open Access   (Followers: 2)
Asian J. of Oncology     Open Access   (Followers: 1)
Asian J. of Transfusion Science     Open Access   (Followers: 2, SJR: 0.362, h-index: 10)
Astrocyte     Open Access  
Avicenna J. of Medicine     Open Access   (Followers: 1)
AYU : An international quarterly journal of research in Ayurveda     Open Access   (Followers: 6)
Benha Medical J.     Open Access  
BLDE University J. of Health Sciences     Open Access  
Brain Circulation     Open Access  
Bulletin of Faculty of Physical Therapy     Open Access   (Followers: 1)
Cancer Translational Medicine     Open Access   (Followers: 1)
CHRISMED J. of Health and Research     Open Access  
Clinical Dermatology Review     Open Access   (Followers: 1)
Clinical Trials in Degenerative Diseases     Open Access  
Clinical Trials in Orthopedic Disorders     Open Access   (Followers: 1)
Community Acquired Infection     Open Access  
Conservation and Society     Open Access   (Followers: 12, SJR: 0.82, h-index: 12)
Contemporary Clinical Dentistry     Open Access   (Followers: 4)
Current Medical Issues     Open Access   (Followers: 1)
CytoJ.     Open Access   (Followers: 2, SJR: 0.339, h-index: 19)
Delta J. of Ophthalmology     Open Access  
Dental Hypotheses     Open Access   (Followers: 3, SJR: 0.131, h-index: 4)
Dental Research J.     Open Access   (Followers: 9)
Dentistry and Medical Research     Open Access  
Digital Medicine     Open Access  
Drug Development and Therapeutics     Open Access  
Education for Health     Open Access   (Followers: 5, SJR: 0.205, h-index: 22)
Egyptian J. of Bronchology     Open Access  
Egyptian J. of Cardiothoracic Anesthesia     Open Access  
Egyptian J. of Cataract and Refractive Surgery     Open Access   (Followers: 1)
Egyptian J. of Dermatology and Venerology     Open Access   (Followers: 1)
Egyptian J. of Haematology     Open Access  
Egyptian J. of Internal Medicine     Open Access   (Followers: 1)
Egyptian J. of Neurology, Psychiatry and Neurosurgery     Open Access   (Followers: 1, SJR: 0.121, h-index: 3)
Egyptian J. of Obesity, Diabetes and Endocrinology     Open Access  
Egyptian J. of Otolaryngology     Open Access   (Followers: 2)
Egyptian J. of Psychiatry     Open Access   (Followers: 2)
Egyptian J. of Surgery     Open Access   (Followers: 1)
Egyptian Orthopaedic J.     Open Access  
Egyptian Pharmaceutical J.     Open Access  
Egyptian Retina J.     Open Access  
Egyptian Rheumatology and Rehabilitation     Open Access  
Endodontology     Open Access  
Endoscopic Ultrasound     Open Access   (SJR: 0.473, h-index: 8)
Environmental Disease     Open Access   (Followers: 2)
European J. of Dentistry     Open Access   (Followers: 2, SJR: 0.496, h-index: 11)
European J. of General Dentistry     Open Access   (Followers: 1)
European J. of Prosthodontics     Open Access   (Followers: 2)
European J. of Psychology and Educational Studies     Open Access   (Followers: 8)
Fertility Science and Research     Open Access  
Formosan J. of Surgery     Open Access   (SJR: 0.107, h-index: 5)
Genome Integrity     Open Access   (Followers: 4, SJR: 1.227, h-index: 12)
Global J. of Transfusion Medicine     Open Access   (Followers: 2)
Heart India     Open Access   (Followers: 1)
Heart Views     Open Access   (Followers: 2)
Hepatitis B Annual     Open Access   (Followers: 3)
IJS Short Reports     Open Access  
Indian Anaesthetists Forum     Open Access  
Indian Dermatology Online J.     Open Access   (Followers: 3)
Indian J. of Allergy, Asthma and Immunology     Open Access   (Followers: 1)
Indian J. of Anaesthesia     Open Access   (Followers: 8, SJR: 0.302, h-index: 13)
Indian J. of Burns     Open Access   (Followers: 1)
Indian J. of Cancer     Open Access   (SJR: 0.318, h-index: 26)
Indian J. of Cerebral Palsy     Open Access   (Followers: 1)
Indian J. of Community Medicine     Open Access   (Followers: 2, SJR: 0.618, h-index: 16)
Indian J. of Critical Care Medicine     Open Access   (Followers: 2, SJR: 0.307, h-index: 16)
Indian J. of Dental Research     Open Access   (Followers: 4, SJR: 0.243, h-index: 24)
Indian J. of Dental Sciences     Open Access  
Indian J. of Dentistry     Open Access   (Followers: 1)
Indian J. of Dermatology     Open Access   (Followers: 2, SJR: 0.448, h-index: 16)
Indian J. of Dermatology, Venereology and Leprology     Open Access   (Followers: 3, SJR: 0.563, h-index: 29)
Indian J. of Dermatopathology and Diagnostic Dermatology     Open Access  
Indian J. of Drugs in Dermatology     Open Access   (Followers: 1)
Indian J. of Endocrinology and Metabolism     Open Access   (Followers: 4)
Indian J. of Health Sciences     Open Access   (Followers: 2)
Indian J. of Medical and Paediatric Oncology     Open Access   (SJR: 0.292, h-index: 9)
Indian J. of Medical Microbiology     Open Access   (Followers: 1, SJR: 0.53, h-index: 34)
Indian J. of Medical Research     Open Access   (Followers: 4, SJR: 0.716, h-index: 60)
Indian J. of Medical Sciences     Open Access   (Followers: 2, SJR: 0.207, h-index: 31)
Indian J. of Multidisciplinary Dentistry     Open Access   (Followers: 1)
Indian J. of Nephrology     Open Access   (Followers: 2, SJR: 0.233, h-index: 12)
Indian J. of Nuclear Medicine     Open Access   (Followers: 2, SJR: 0.213, h-index: 5)
Indian J. of Occupational and Environmental Medicine     Open Access   (Followers: 4, SJR: 0.203, h-index: 13)
Indian J. of Ophthalmology     Open Access   (Followers: 5, SJR: 0.536, h-index: 34)
Indian J. of Oral Health and Research     Open Access  
Indian J. of Oral Sciences     Open Access   (Followers: 1)
Indian J. of Orthopaedics     Open Access   (Followers: 9, SJR: 0.393, h-index: 15)
Indian J. of Otology     Open Access   (Followers: 1, SJR: 0.218, h-index: 5)
Indian J. of Paediatric Dermatology     Open Access   (Followers: 2)
Indian J. of Pain     Open Access   (Followers: 1)
Indian J. of Palliative Care     Open Access   (Followers: 5, SJR: 0.35, h-index: 12)
Indian J. of Pathology and Microbiology     Open Access   (Followers: 1, SJR: 0.285, h-index: 22)
Indian J. of Pharmacology     Open Access   (SJR: 0.347, h-index: 44)
Indian J. of Plastic Surgery     Open Access   (Followers: 12, SJR: 0.303, h-index: 13)
Indian J. of Psychiatry     Open Access   (Followers: 3, SJR: 0.496, h-index: 15)
Indian J. of Psychological Medicine     Open Access   (Followers: 1, SJR: 0.344, h-index: 9)
Indian J. of Public Health     Open Access   (Followers: 1, SJR: 0.444, h-index: 17)
Indian J. of Radiology and Imaging     Open Access   (Followers: 4, SJR: 0.253, h-index: 14)
Indian J. of Research in Homoeopathy     Open Access  
Indian J. of Rheumatology     Open Access   (SJR: 0.169, h-index: 7)
Indian J. of Sexually Transmitted Diseases and AIDS     Open Access   (Followers: 2, SJR: 0.313, h-index: 9)
Indian J. of Social Psychiatry     Open Access   (Followers: 2)
Indian J. of Urology     Open Access   (Followers: 3, SJR: 0.366, h-index: 16)
Indian J. of Vascular and Endovascular Surgery     Open Access   (Followers: 2)
Industrial Psychiatry J.     Open Access   (Followers: 2)
Intl. J. of Academic Medicine     Open Access  
Intl. J. of Advanced Medical and Health Research     Open Access  
Intl. J. of Applied and Basic Medical Research     Open Access  
Intl. J. of Clinical and Experimental Physiology     Open Access   (Followers: 1)
Intl. J. of Critical Illness and Injury Science     Open Access   (Followers: 1)
Intl. J. of Educational and Psychological Researches     Open Access   (Followers: 4)
Intl. J. of Environmental Health Engineering     Open Access   (Followers: 1)
Intl. J. of Forensic Odontology     Open Access   (Followers: 1)
Intl. J. of Green Pharmacy     Open Access   (Followers: 4, SJR: 0.229, h-index: 13)
Intl. J. of Health & Allied Sciences     Open Access   (Followers: 3)
Intl. J. of Health System and Disaster Management     Open Access   (Followers: 3)
Intl. J. of Heart Rhythm     Open Access  
Intl. J. of Medicine and Public Health     Open Access   (Followers: 7)
Intl. J. of Mycobacteriology     Open Access   (SJR: 0.239, h-index: 4)
Intl. J. of Noncommunicable Diseases     Open Access  
Intl. J. of Nutrition, Pharmacology, Neurological Diseases     Open Access   (Followers: 4)
Intl. J. of Oral Health Sciences     Open Access   (Followers: 1)
Intl. J. of Orthodontic Rehabilitation     Open Access  
Intl. J. of Pedodontic Rehabilitation     Open Access  
Intl. J. of Pharmaceutical Investigation     Open Access   (Followers: 1)
Intl. J. of Preventive Medicine     Open Access   (Followers: 1, SJR: 0.523, h-index: 15)
Intl. J. of Shoulder Surgery     Open Access   (Followers: 7, SJR: 0.611, h-index: 9)
Intl. J. of Trichology     Open Access   (SJR: 0.37, h-index: 10)
Intl. J. of Yoga     Open Access   (Followers: 15)
Intl. J. of Yoga : Philosophy, Psychology and Parapsychology     Open Access   (Followers: 6)
Iranian J. of Nursing and Midwifery Research     Open Access   (Followers: 3)
Iraqi J. of Hematology     Open Access  
J. of Academy of Medical Sciences     Open Access  
J. of Advanced Pharmaceutical Technology & Research     Open Access   (Followers: 4, SJR: 0.427, h-index: 15)
J. of Anaesthesiology Clinical Pharmacology     Open Access   (Followers: 8, SJR: 0.416, h-index: 14)
J. of Applied Hematology     Open Access  
J. of Association of Chest Physicians     Open Access   (Followers: 2)
J. of Basic and Clinical Reproductive Sciences     Open Access   (Followers: 1)
J. of Cancer Research and Therapeutics     Open Access   (Followers: 4, SJR: 0.359, h-index: 21)
J. of Carcinogenesis     Open Access   (Followers: 1, SJR: 1.152, h-index: 26)
J. of Cardiothoracic Trauma     Open Access  
J. of Cardiovascular Disease Research     Open Access   (Followers: 3, SJR: 0.351, h-index: 13)
J. of Cardiovascular Echography     Open Access   (SJR: 0.134, h-index: 2)
J. of Cleft Lip Palate and Craniofacial Anomalies     Open Access   (Followers: 2)
J. of Clinical and Preventive Cardiology     Open Access   (Followers: 1)
J. of Clinical Imaging Science     Open Access   (Followers: 1, SJR: 0.277, h-index: 8)
J. of Clinical Neonatology     Open Access   (Followers: 1)
J. of Clinical Ophthalmology and Research     Open Access   (Followers: 2)
J. of Clinical Sciences     Open Access  
J. of Conservative Dentistry     Open Access   (Followers: 4, SJR: 0.532, h-index: 10)
J. of Craniovertebral Junction and Spine     Open Access   (Followers: 4, SJR: 0.199, h-index: 9)
J. of Current Medical Research and Practice     Open Access  
J. of Current Research in Scientific Medicine     Open Access  
J. of Cutaneous and Aesthetic Surgery     Open Access   (Followers: 1)
J. of Cytology     Open Access   (Followers: 1, SJR: 0.274, h-index: 9)
J. of Dental and Allied Sciences     Open Access   (Followers: 1)
J. of Dental Implants     Open Access   (Followers: 7)
J. of Dental Lasers     Open Access   (Followers: 2)
J. of Dental Research and Review     Open Access   (Followers: 1)
J. of Digestive Endoscopy     Open Access   (Followers: 3)
J. of Dr. NTR University of Health Sciences     Open Access  
J. of Earth, Environment and Health Sciences     Open Access   (Followers: 1)
J. of Education and Ethics in Dentistry     Open Access   (Followers: 5)
J. of Education and Health Promotion     Open Access   (Followers: 5)
J. of Emergencies, Trauma and Shock     Open Access   (Followers: 9, SJR: 0.353, h-index: 14)
J. of Engineering and Technology     Open Access   (Followers: 6)
J. of Experimental and Clinical Anatomy     Open Access   (Followers: 2)
J. of Family and Community Medicine     Open Access   (Followers: 2)
J. of Family Medicine and Primary Care     Open Access   (Followers: 11)

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Journal Cover Indian Journal of Nephrology
  [SJR: 0.233]   [H-I: 12]   [2 followers]  Follow
    
  This is an Open Access Journal Open Access journal
   ISSN (Print) 0971-4065 - ISSN (Online) 1998-3662
   Published by Medknow Publishers Homepage  [355 journals]
  • Nocturnal enuresis in india: Are we diagnosing and managing
           correctly?

    • Authors: NM Reddy, H Malve, R Nerli, P Venkatesh, I Agarwal, V Rege
      Pages: 417 - 426
      Abstract: NM Reddy, H Malve, R Nerli, P Venkatesh, I Agarwal, V Rege
      Indian Journal of Nephrology 2017 27(6):417-426
      Nocturnal enuresis is a common problem affecting school-aged children worldwide. Although it has significant impact on child's psychology, it is always under-recognized in India and considered as a condition which will outgrow with advancing age. Nocturnal enuresis classified as primary or secondary and monosymptomatic or nonmonosymptomatic. Factors that cause enuresis include genetic factors, bladder dysfunction, psychological factors, and inappropriate antidiuretic hormone secretion, leading to nocturnal polyuria. Diagnosis consists of detailed medical history, clinical examination, frequency-volume charts, and appropriate investigations. The frequency-volume chart or voiding diary helps in establishing diagnosis and tailoring therapy. The first step in treating nocturnal enuresis is to counsel the parents and the affected child about the condition and reassure them that it can be cured. One of the effective strategies to manage enuresis is alarm therapy, but currently, it is not easily available in India. Desmopressin has been used in the treatment of nocturnal enuresis for close to 50 years. It provides an effective and safe option for the management of nocturnal enuresis. This review covers the diagnosis and management of nocturnal enuresis and introduces the concept of “bedwetting clinics” in India, which should help clinicians in the thorough investigation of bedwetting cases.
      Citation: Indian Journal of Nephrology 2017 27(6):417-426
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_288_16
      Issue No: Vol. 27, No. 6 (2017)
       
  • Central venous stenosis: What should a nephrologist know?

    • Authors: HJ Mehta
      Pages: 427 - 429
      Abstract: HJ Mehta
      Indian Journal of Nephrology 2017 27(6):427-429

      Citation: Indian Journal of Nephrology 2017 27(6):427-429
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/0971-4065.202825
      Issue No: Vol. 27, No. 6 (2017)
       
  • A randomized controlled trial of intravenous versus oral cyclophosphamide
           in steroid-resistant nephrotic syndrome in children

    • Authors: KM Shah, AJ Ohri, US Ali
      Pages: 430 - 434
      Abstract: KM Shah, AJ Ohri, US Ali
      Indian Journal of Nephrology 2017 27(6):430-434
      This is a randomized, parallel group, active-controlled trial to compare the efficacy of intravenous cyclophosphamide (IVCP) with oral cyclophosphamide (OCP) in patients with steroid-resistant nephrotic syndrome (SRNS) in children. Fifty consecutive children with idiopathic SRNS were biopsied and then randomized to receive either OCP at a dose of 2 mg/kg/day for 12 weeks or IVCP at a dose of 500 mg/m2/month for 6 months. Both groups received tapering doses of oral steroids. The response was evaluated in terms of induction of complete remission (CR) or partial remission (PR), time to remit, and side effects. The groups were followed up to determine the duration of remission, percentage of patients who remain in sustained remission for more than 1 year after completion of therapy, change in steroid response status, progression to chronic kidney disease stage 3 or more. Of the fifty patients, OCP was given to 25 children and IVCP to 25 children. The demographic data, histopathology, biochemical profile, and duration of follow-up in the two groups were comparable. The rates of induction of CR were 52% versus 44% and of PR were 8% versus 8% in the intravenous (IV) and oral group, respectively. Time to remit was shorter with OCP than IVCP (53 days vs. 84.4 days). Incidence of side effects (both major and minor) was 36% in IVCP versus 20% in OCP group. The actuarial cumulative sustained remission in our study was 12% in IVCP compared with 16% in OCP at 1 year after completion of therapy. Twelve percent children in both the groups exhibited restoration of steroid sensitivity. Thus, in our study, overall, more than half of SRNS patients showed initial response to cyclophosphamide, but only one-fourth patients had sustained remission on follow-up. OCP and IVCP were equally efficacious and safe in idiopathic SRNS in children.
      Citation: Indian Journal of Nephrology 2017 27(6):430-434
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_201_16
      Issue No: Vol. 27, No. 6 (2017)
       
  • IgA-dominant infection-related glomerulonephritis in India: A
           single-center experience

    • Authors: J Dhanapriya, T Balasubramaniyan, SP Maharajan, T Dineshkumar, R Sakthirajan, N Gopalakrishnan, M Nagarajan
      Pages: 435 - 439
      Abstract: J Dhanapriya, T Balasubramaniyan, SP Maharajan, T Dineshkumar, R Sakthirajan, N Gopalakrishnan, M Nagarajan
      Indian Journal of Nephrology 2017 27(6):435-439
      IgA-dominant infection-related glomerulonephritis (IRGN) is a distinct morphologic variant of IRGN, characterized by dominant or codominant glomerular deposits of IgA, mostly in elderly and patients with diabetes. More cases are being reported in recent times due to increased awareness of the disease entity and increased rate of Staphylococcus infection. It usually presents as rapidly progressive renal failure with proteinuria, and treatment guidelines for this disease entity are not well defined. We report here 12 cases of IgA-dominant IRGN seen over a period of 5 years from a single center. Clinical features, biopsy findings, treatment, and outcomes were analyzed. Out of 12 patients, eight were males. The mean age of presentation was 52.4 ± 21 years. Skin was the most common site of infection seen in six patients. Gross hematuria was seen in 4 patients and 11 had nephrotic proteinuria. Eleven had low serum C3. Only two patients had diabetes. Methicillin-resistant Staphylococcus aureus (MRSA) was the most common organism isolated in six patients. Most common histopathology was crescentic glomerulonephritis seen in seven patients, followed by endocapillary proliferation in three and diffuse proliferative glomerulonephritis in two. Hemodialysis was done in eight patients and six patients received steroid therapy. End-stage renal disease developed in three patients, chronic kidney disease in three, and three patients died due to sepsis. Various infections including MRSA and Escherichia coli were associated with IgA-dominant IRGN both in patients with diabetes and nondiabetics. Suspicion and recognition of the disease is important as it has therapeutic and prognostic implications.
      Citation: Indian Journal of Nephrology 2017 27(6):435-439
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_337_16
      Issue No: Vol. 27, No. 6 (2017)
       
  • Renal manifestation in scrub typhus during a major outbreak in central
           Nepal

    • Authors: A Sedhain, GR Bhattarai
      Pages: 440 - 445
      Abstract: A Sedhain, GR Bhattarai
      Indian Journal of Nephrology 2017 27(6):440-445
      Renal involvement and acute kidney injury (AKI) are common clinical manifestations seen in scrub typhus, a vector-borne tropical disease. There are no data on renal manifestation in scrub typhus in Nepal. We conducted a prospective study to analyze the incidence, urinary abnormalities, course, severity, outcome, and the predictors of AKI in patients with scrub typhus during a major outbreak in Central Nepal. Total 1398 patients admitted with acute febrile illness were subjected for Scrub Typhus Detect™ Immunoglobulin M (IgM) enzyme-linked immunosorbent assay (ELISA) test, of which 502 (35.90%) patients tested positive and were included in the study. Mean age of the patients was 30.37 ± 18.81 years (range, 1–79 years) with 26.29% in the pediatric age group. Female-to-male ratio was 1.26:1. Mean duration of fever was 6.8 ± 3.1 days. Mean IgM ELISA value for scrub typhus was 2.17 ± 1.70 without difference in AKI and non-AKI groups (2.17 ± 1.76 vs. 2.16 ± 1.62; P = 0.94). Urinary abnormalities were seen in 42.3% of patients. Mean serum creatinine was 1.37 ± 0.69 mg/dl with significant difference in two groups (1.85 ± 0.87 vs. 1.03 ± 0.17; P = 0.003). AKI was seen in 35.8% of patients with majority having Stage 1 AKI (68.3%) followed by Stage 2 (34.1%) and Stage 3 (1.2%). Hemodialysis was required for 3.94% of patients. In 54% of patients, AKI occurred in fifth and sixth day of fever. ICU admission was required for 18.73% of patients and 8.57% required ventilator support. Mortality rate was 1.79%, which was higher among patients with AKI (2.96% vs. 1.0%; P = 0.106). Multivariate analysis revealed that the presence of pneumonia, shock, and acute respiratory distress syndrome predicted the development of AKI.
      Citation: Indian Journal of Nephrology 2017 27(6):440-445
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_133_17
      Issue No: Vol. 27, No. 6 (2017)
       
  • Reduced baroreflex sensitivity, decreased heart rate variability with
           increased arterial stiffness in predialysis

    • Authors: C Lal, M Kaur, AK Jaryal, KK Deepak, D Bhowmik, SK Agarwal
      Pages: 446 - 451
      Abstract: C Lal, M Kaur, AK Jaryal, KK Deepak, D Bhowmik, SK Agarwal
      Indian Journal of Nephrology 2017 27(6):446-451
      High cardiovascular morbidity and mortality is observed in predialytic chronic kidney disease (CKD) patients. The underlying mechanism of cardiovascular dysfunction often remains unclear. The present study was designed to perform multiparametric assessment of baroreflex sensitivity (BRS), arterial stiffness indices, and cardiovascular variabilities (heart rate variability [HRV] and blood pressure variability [BPV]) together in predialytic CKD patients; compare it with normal healthy controls; and determine their relationships in predialytic nondiabetic CKD patients. Thirty CKD Stage 4 and 5 predialytic non-diabetic patients and 30 healthy controls were enrolled in the study. BRS was determined by spontaneous sequence method. Short-term HRV and BPV were assessed using 5 min beat-to-beat data of RR intervals and blood pressure by time domain and frequency domain analysis. Arterial stiffness indices - carotid-femoral pulse wave velocity (PWV) and augmentation index - were measured using SphygmoCor Vx device (AtCor Medical, Australia). Predialytic CKD patients had significantly low BRS, high PWV, and low HRV as compared to healthy controls. Independent predictors of reduced systolic BRS in predialytic CKD patient group on multiple regression analysis emerged to be increase in calcium-phosphate product, increase in BPV, and decrease in HRV. Predialytic nondiabetic CKD Stage 4 and 5 patients have poor hemodynamic profile (higher PWV, lower HRV, and reduced BRS) than healthy controls. Reduced HRV and altered calcium-phosphate homeostasis emerged to be significant independent predictors of reduced BRS.
      Citation: Indian Journal of Nephrology 2017 27(6):446-451
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_63_17
      Issue No: Vol. 27, No. 6 (2017)
       
  • Innominate vein stenosis in association with ipsilateral hyperdynamic
           brachiobasilic fistula causing ipsilateral limb and hemifacial swelling

    • Authors: JB Narendra, J Sreenivas, VS Karthikeyan, NH Nagaraja
      Pages: 452 - 455
      Abstract: JB Narendra, J Sreenivas, VS Karthikeyan, NH Nagaraja
      Indian Journal of Nephrology 2017 27(6):452-455
      A 34-year-old hypertensive woman with a hyperdynamic, left brachiobasilic dialysis fistula presented with a long history of throbbing in her head and swelling of the left side of the face. Tight stenosis of left brachiocephalic vein was found to be causing retrograde flow into the left jugular vein which normalized after dilatation and stenting with resolution of all the symptoms and patient is asymptomatic for 1 year.
      Citation: Indian Journal of Nephrology 2017 27(6):452-455
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/0971-4065.194393
      Issue No: Vol. 27, No. 6 (2017)
       
  • Squamous cell carcinoma of skin after 20 years of renal transplantation

    • Authors: J Poddar, AD Sharma, S Patel, U Suryanarayana
      Pages: 456 - 458
      Abstract: J Poddar, AD Sharma, S Patel, U Suryanarayana
      Indian Journal of Nephrology 2017 27(6):456-458
      Solid organ transplant recipients are at high risk of developing malignancies due to the prolonged use of immunosuppressant drugs. Squamous cell carcinoma of skin can occur in these patients even after decades of organ transplant. A 45-year-old male underwent renal transplant for end-stage renal disease 23 years ago and was on immunosuppressive drugs since then. The patient was on regular follow-up. Three years back, he developed squamous cell carcinoma of both forearms and hands, which was treated with radiation therapy using 8 MeV electrons, by parallel opposed fields to a dose of 60 Gy/30 fractions. Complete response to treatment was achieved at 3 months posttreatment. The patient is currently on follow-up and asymptomatic for skin lesions. Hence, these patients require longer follow-up, active surveillance, and screening for early diagnosis and prompt treatment of the premalignant and malignant conditions.
      Citation: Indian Journal of Nephrology 2017 27(6):456-458
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_308_16
      Issue No: Vol. 27, No. 6 (2017)
       
  • How harmful can herbal remedies be? a case of severe acute
           tubulointerstitial nephritis

    • Authors: P Beniwal, N Gaur, SK Singh, N Raveendran, V Malhotra
      Pages: 459 - 461
      Abstract: P Beniwal, N Gaur, SK Singh, N Raveendran, V Malhotra
      Indian Journal of Nephrology 2017 27(6):459-461
      Acute interstitial nephritis (AIN) is a condition in which acute kidney injury (AKI) is characterized by the histological finding of interstitial inflammation. Hyponidd is an ayurvedic drug containing Momordica charantia, Gymnema sylvestre, Swertia chirata, etc., used for the treatment of Type 2 diabetes mellitus (DM) and polycystic ovarian disease as an insulin sensitizer. There are no case reports of AIN caused by this drug yet. We report a biopsy-proven case of AKI due to severe AIN associated with the use of hyponidd tablet in a 60-year-old male with DM and hypertension. As these types of various indigenous compounds are used as home remedies in our country, awareness about the possible adverse effects of these agents among physicians is very important in the early diagnosis and management.
      Citation: Indian Journal of Nephrology 2017 27(6):459-461
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_313_16
      Issue No: Vol. 27, No. 6 (2017)
       
  • Acute thyroid swelling in renal transplant recipient

    • Authors: DP Engineer, S Prakash, A Yadav, J Kumhar, A Biswas, G Kunal, A Goel
      Pages: 462 - 464
      Abstract: DP Engineer, S Prakash, A Yadav, J Kumhar, A Biswas, G Kunal, A Goel
      Indian Journal of Nephrology 2017 27(6):462-464
      Tuberculosis (TB) of thyroid gland is rare entity even in solid organ transplant recipients who have a high risk of TB. Thyroid TB is easily diagnosed by fine needle aspiration cytology. The majority of cases require only antitubercular drugs for treatment, and surgical intervention is required only in few patients. We here describe a case of thyroid TB presenting as an acute abscess in postrenal transplant recipient with a background of acute rejection treated with steroid and antithymocyte globulin.
      Citation: Indian Journal of Nephrology 2017 27(6):462-464
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_335_16
      Issue No: Vol. 27, No. 6 (2017)
       
  • Methylene blue induced methemoglobinemia with acute kidney injury in a
           glucose-6-phosphate dehydrogenase-deficient patient

    • Authors: MR Balwani, CP Bawankule, V Ramteke, P Tolani, S Vakil, R Yadav
      Pages: 465 - 467
      Abstract: MR Balwani, CP Bawankule, V Ramteke, P Tolani, S Vakil, R Yadav
      Indian Journal of Nephrology 2017 27(6):465-467
      Our case was treated with methylene blue for symptomatic nitrobenzene poisoning. After which he developed methemoglobinemia with acute kidney injury due to hemolysis and on further testing, he was found to be glucose-6-phosphate dehydrogenase (G6PD) enzyme deficient. Thus, afterward, the patient was treated with only available mode of treatment as repeated blood transfusions and ascorbic acid with dialysis support to which the patient responded. Thus, it is important to evaluate for the G6PD deficiency where methylene blue treatment is planned as an antidote to nitrobenzene compounds poisoning.
      Citation: Indian Journal of Nephrology 2017 27(6):465-467
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_316_16
      Issue No: Vol. 27, No. 6 (2017)
       
  • Renal complications of hematopoietic stem cell transplantation: Report of
           a case and review of the literature

    • Authors: E Liquete, SR Williamson, N Janakiraman, KK Venkat
      Pages: 468 - 471
      Abstract: E Liquete, SR Williamson, N Janakiraman, KK Venkat
      Indian Journal of Nephrology 2017 27(6):468-471
      We report the development of minimal change disease superimposed on preexisting chronic kidney disease secondary to chronic calcineurin inhibitor nephrotoxicity in a hematopoietic stem cell transplantation (HSCT) recipient and review the renal complications of HSCT.
      Citation: Indian Journal of Nephrology 2017 27(6):468-471
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_230_16
      Issue No: Vol. 27, No. 6 (2017)
       
  • Nutcracker syndrome with hypertension as an unusual initial presentation

    • Authors: NA Narkhede, AB Deokar, KP Mehta, NN Kamat
      Pages: 472 - 474
      Abstract: NA Narkhede, AB Deokar, KP Mehta, NN Kamat
      Indian Journal of Nephrology 2017 27(6):472-474
      Hypertension has been rarely reported in patients with the nutcracker phenomenon (NCP)/syndrome. We describe a case of a young adolescent female patient where a computed tomography angiography (CTA) provided evidence of left renal vein dilatation, probably due to its compression through the angle between the aorta and the superior mesenteric artery, during the evaluation of secondary hypertension. Blood levels of renin and aldosterone were within normal limits. Ultrasonography of the kidney showed minimal scarring on the left side. As there were no other signs of secondary hypertension, we proceeded with a CTA, which revealed findings compatible with the so-called NCP/syndrome.
      Citation: Indian Journal of Nephrology 2017 27(6):472-474
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_184_16
      Issue No: Vol. 27, No. 6 (2017)
       
  • Spontaneous splenic haematoma in a patient on hemodialysis: A case report

    • Authors: J Pandiaraja
      Pages: 475 - 477
      Abstract: J Pandiaraja
      Indian Journal of Nephrology 2017 27(6):475-477
      Spontaneous splenic hematoma is one of the rare and life-threatening complications of chronic renal failure. The diagnosis of splenic hematoma is mostly made by imaging such as ultrasound or computed tomography. The management of spontaneous splenic hematoma is not standardized till now due to the rarity of this condition. Splenectomy is recommended in hemodynamically unstable patients with features of shock. This is a case report of spontaneous splenic hematoma in a patient with chronic renal failure. This case is reported due to the rarity with renal failure.
      Citation: Indian Journal of Nephrology 2017 27(6):475-477
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_285_16
      Issue No: Vol. 27, No. 6 (2017)
       
  • Nontubercular mycobacterial infection in a renal allograft recipient

    • Authors: U Anandh, K Jayanna
      Pages: 478 - 481
      Abstract: U Anandh, K Jayanna
      Indian Journal of Nephrology 2017 27(6):478-481
      A 71-year-old male, a renal allograft recipient, presented to us with a history of fever and right palm swelling. He had a history of fever 7 years back when he was treated with antitubercular treatment (ATT). Three years back, he was diagnosed to have gout and he was started on allopurinol. He developed severe bone marrow toxicity and allopurinol was changed to febuxostat. On admission, routine investigations did not reveal any focus of infection. The fluid aspirate from the palm revealed acid-fast bacilli (AFB). He was started on ATT; however, he did not show significant improvement. Two months later, he developed multiple subcutaneous lesions, and the pus again came positive for AFB. Due to lack of improvement, the aspirate was sent for molecular diagnostic identification. The mycobacteria was identified as Mycobacterium haemophilum. His treatment was changed to rifampicin, clarithromycin, and ciprofloxacin. As he showed slow improvement, his immunosuppression was tapered slowly. At 7 months of therapy, he is clinically better and his lesions are healing. His renal functions stayed stable despite tapering of cyclosporine in a patient who is on rifampicin. This case, the first report of M. haemophilum infection in a kidney transplant recipient in India, illustrates the difficulty in diagnosing nontubercular mycobacterial infection in transplant recipients. It also emphasizes the dilemma in tapering immunosuppressive drugs in disseminated nontubercular mycobacterial infections where there are considerable interactions between ATT and immunosuppressives.
      Citation: Indian Journal of Nephrology 2017 27(6):478-481
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_336_16
      Issue No: Vol. 27, No. 6 (2017)
       
  • Trimethoprim-sulfamethoxazole-induced hepatotoxicity in a renal transplant
           patient

    • Authors: R Slim, N Asmar, C Yaghi, K Honein, R Sayegh, D Chelala
      Pages: 482 - 483
      Abstract: R Slim, N Asmar, C Yaghi, K Honein, R Sayegh, D Chelala
      Indian Journal of Nephrology 2017 27(6):482-483
      Drug-induced liver injury (DILI) represents liver damage from various therapeutic drugs. Antimicrobials are among the most common causes of DILI. We report a case of hepatic toxicity due to Trimethoprim-sulfamethoxazole (TMP-SMX) in a patient who underwent renal transplantation. Diagnosis has been made after a careful history taking, exclusion of competing etiologies and reversal of biochemical abnormalities after withdrawal of the antibiotic. TMP-SMX liver toxicity is well known but remains unpredictable and is rarely reported.
      Citation: Indian Journal of Nephrology 2017 27(6):482-483
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_339_16
      Issue No: Vol. 27, No. 6 (2017)
       
  • Bowel migration of dormant chronic ambulatory peritoneal dialysis
           catheter: A vexed problem not avoided by flushing

    • Authors: P Vincent, J Gopinathan, R Narayanan
      Pages: 484 - 486
      Abstract: P Vincent, J Gopinathan, R Narayanan
      Indian Journal of Nephrology 2017 27(6):484-486
      Delayed bowel erosion by peritoneal dialysis catheter is rare with fewer than thirty cases having been reported in the literature. This complication is usually encountered when the catheter is kept dormant. Two cases have also been reported with catheters in active use. The risk factors for bowel erosion include immunosuppression, diverticulosis, and amyloidosis. An 80-year-old male with chronic kidney disease Stage 5 due to hypertensive nephrosclerosis underwent chronic ambulatory peritoneal dialysis catheter insertion. Due to improvement in the glomerular filtration rate and clinical parameters including extracellular fluid volume status, peritoneal dialysis was not initiated. Weekly catheter flushes were performed. After 5 months, he developed watery diarrhea after a regular flushing episode. Computed tomography scan revealed the catheter displaced into the sigmoid colon with the tip in the rectum. He was managed successfully with catheter removal alone and conservative treatment. He remains asymptomatic at 3-month follow-up. This case is presented to emphasize the fact that delayed bowel erosion can happen with dormant catheter even in the absence of risk factors. Periodic flushing has not prevented this complication in our patient. Perforations can be self-curing when diagnosed early and when patients present without features of peritonitis or sepsis. Such cases can be managed successfully with catheter removal alone.
      Citation: Indian Journal of Nephrology 2017 27(6):484-486
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_268_16
      Issue No: Vol. 27, No. 6 (2017)
       
  • Strongyloid hyperinfection syndrome in a renal transplant recipient

    • Authors: S Sriperumbuduri, K Kalidindi, S Guditi, G Taduri
      Pages: 487 - 488
      Abstract: S Sriperumbuduri, K Kalidindi, S Guditi, G Taduri
      Indian Journal of Nephrology 2017 27(6):487-488

      Citation: Indian Journal of Nephrology 2017 27(6):487-488
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_246_16
      Issue No: Vol. 27, No. 6 (2017)
       
  • Streptococcus gallolyticus subsp. pasteurianus peritonitis in a patient on
           continuous ambulatory peritoneal dialysis

    • Authors: M Shanmuganathan, BL Goh, C.T.S. Lim
      Pages: 488 - 489
      Abstract: M Shanmuganathan, BL Goh, C.T.S. Lim
      Indian Journal of Nephrology 2017 27(6):488-489

      Citation: Indian Journal of Nephrology 2017 27(6):488-489
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_245_16
      Issue No: Vol. 27, No. 6 (2017)
       
  • Efficacy of thalidomide for recurrent gastrointestinal bleeding due to
           angiodysplasias in a hemodialysis patient

    • Authors: M Tamzaourte, Y Zajjari
      Pages: 489 - 490
      Abstract: M Tamzaourte, Y Zajjari
      Indian Journal of Nephrology 2017 27(6):489-490

      Citation: Indian Journal of Nephrology 2017 27(6):489-490
      PubDate: Tue,14 Nov 2017
      DOI: 10.4103/ijn.IJN_32_17
      Issue No: Vol. 27, No. 6 (2017)
       
 
 
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