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Publisher: Bangladesh Journals Online   (Total: 101 journals)

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Anwer Khan Modern Medical College J.     Open Access   (Followers: 2)
Bangabandhu Sheikh Mujib Medical University J.     Open Access  
Bangladesh Critical Care J.     Open Access  
Bangladesh J. of Agricultural Research     Open Access   (Followers: 3)
Bangladesh J. of Anatomy     Open Access  
Bangladesh J. of Animal Science     Open Access  
Bangladesh J. of Bioethics     Open Access   (Followers: 2)
Bangladesh J. of Botany     Open Access   (SJR: 0.226, h-index: 9)
Bangladesh J. of Child Health     Open Access  
Bangladesh J. of Dental Research & Education     Open Access   (Followers: 2)
Bangladesh J. of Endosurgery     Open Access   (Followers: 2)
Bangladesh J. of Library and Information Science     Open Access   (Followers: 28)
Bangladesh J. of Medical Biochemistry     Open Access   (Followers: 2)
Bangladesh J. of Medical Education     Open Access   (Followers: 1)
Bangladesh J. of Medical Microbiology     Open Access  
Bangladesh J. of Medical Physics     Open Access  
Bangladesh J. of Medical Science     Open Access   (SJR: 0.21, h-index: 3)
Bangladesh J. of Medicine     Open Access   (Followers: 1)
Bangladesh J. of Nutrition     Open Access   (Followers: 3)
Bangladesh J. of Orthodontics and Dentofacial Orthopedics     Open Access  
Bangladesh J. of Otorhinolaryngology     Open Access  
Bangladesh J. of Pharmacology     Open Access   (SJR: 0.243, h-index: 10)
Bangladesh J. of Physiology and Pharmacology     Open Access  
Bangladesh J. of Plant Breeding and Genetics     Open Access   (Followers: 2)
Bangladesh J. of Plant Taxonomy     Open Access   (Followers: 1, SJR: 0.248, h-index: 6)
Bangladesh J. of Plastic Surgery     Open Access  
Bangladesh J. of Scientific and Industrial Research     Open Access  
Bangladesh J. of Scientific Research     Open Access   (Followers: 1)
Bangladesh J. of Urology     Open Access   (Followers: 2)
Bangladesh J. of Veterinary Medicine     Open Access   (Followers: 1)
Bangladesh Medical J.     Open Access  
Bangladesh Medical J. Khulna     Open Access  
Bangladesh Medical Research Council Bulletin     Open Access   (SJR: 0.295, h-index: 13)
Bangladesh Pharmaceutical J.     Full-text available via subscription   (Followers: 1)
Bangladesh Rice J.     Open Access  
Bangladesh Veterinarian     Open Access   (Followers: 1)
BIRDEM Medical J.     Open Access   (Followers: 3)
Cardiovascular J.     Open Access   (Followers: 2)
Chattagram Maa-O-Shishu Hospital Medical College J.     Open Access  
Chemical Engineering Research Bulletin     Open Access   (SJR: 0.207, h-index: 2)
Chittagong University J. of Biological Sciences     Open Access  
City Dental College J.     Open Access   (Followers: 2)
Community Based Medical J.     Open Access  
Delta Medical College J.     Open Access   (Followers: 2)
Dhaka University J. of Biological Sciences     Open Access  
Dhaka University J. of Pharmaceutical Sciences     Open Access   (Followers: 2, SJR: 0.171, h-index: 6)
Dhaka University J. of Science     Open Access  
Eastern Librarian     Open Access   (Followers: 12)
Faridpur Medical College J.     Open Access   (Followers: 1)
GANIT : J. of Bangladesh Mathematical Society     Open Access  
Ibrahim Cardiac Medical J.     Open Access  
Ibrahim Medical College J.     Open Access  
Intl. Current Pharmaceutical J.     Open Access   (Followers: 3)
Intl. J. of Agricultural Research, Innovation and Technology     Open Access   (Followers: 1)
Intl. J. of Natural Sciences     Open Access   (Followers: 1)
Intl. J. of Pharmaceutical and Life Sciences     Open Access   (Followers: 5)
J. of Advanced Veterinary and Animal Research     Open Access   (Followers: 5)
J. of Armed Forces Medical College, Bangladesh     Open Access  
J. of Bangladesh Society of Physiologist     Open Access  
J. of Bio-Science     Open Access   (Followers: 1, SJR: 0.103, h-index: 2)
J. of Business and Technology (Dhaka)     Open Access  
J. of Chemical Engineering     Open Access   (Followers: 4)
J. of Current and Advance Medical Research     Open Access  
J. of Dhaka Medical College     Open Access  
J. of Dhaka National Medical College & Hospital     Open Access  
J. of Enam Medical College     Open Access  
J. of Environmental Science and Natural Resources     Open Access   (Followers: 2)
J. of Life and Earth Science     Open Access  
J. of Mechanical Engineering     Open Access   (Followers: 3, SJR: 0.11, h-index: 1)
J. of Medicine     Open Access   (Followers: 1, SJR: 0.111, h-index: 22)
J. of Naval Architecture and Marine Engineering     Open Access  
J. of Paediatric Surgeons of Bangladesh     Open Access  
J. of Science Foundation     Open Access   (Followers: 2)
J. of Scientific Research     Open Access   (Followers: 1)
J. of Shaheed Suhrawardy Medical College     Open Access  
J. of Surgical Sciences     Open Access  
J. of the Asiatic Society of Bangladesh, Science     Open Access  
J. of the Bangladesh Agricultural University     Open Access  
J. of the Bangladesh Association of Young Researchers     Open Access  
J. of the Bangladesh Chemical Society     Open Access  
J. of the Bangladesh Society of Anaesthesiologists     Open Access  
Jahangirnagar University Environmental Bulletin     Open Access  
KYAMC J.     Open Access   (Followers: 1)
Medicine Today     Open Access   (SJR: 0.188, h-index: 5)
Mediscope     Open Access  
Microbes and Health     Open Access   (Followers: 2)
Northern Intl. Medical College J.     Open Access  
Northern University J. of Law     Open Access  
Philosophy and Progress     Open Access  
Progressive Agriculture     Open Access   (Followers: 1)
Pulse : Medical J. of Apollo Hospitals Dhaka     Open Access  
Rajshahi University J. of Life & Earth and Agricultural Sciences     Open Access   (Followers: 1)
Research in Agriculture, Livestock and Fisheries     Open Access  
SAARC J. of Agriculture     Open Access  
South East Asia J. of Public Health     Open Access   (Followers: 2)
Stamford J. of English     Open Access   (Followers: 1)
Stamford J. of Microbiology     Open Access  
The Agriculturists     Open Access  
University Heart J.     Open Access  
University J. of Zoology, Rajshahi University     Open Access   (SJR: 0.102, h-index: 2)

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Journal Cover   Bangladesh Pharmaceutical Journal
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   Full-text available via subscription Subscription journal
   ISSN (Print) 0301-4606
   Published by Bangladesh Journals Online Homepage  [101 journals]
  • In vitro Bioactivities of Three Reputed Medicinal Plants of Bangladesh
    • Authors: Abu Bakar Siddique, Ridwan Islam, Md Al Amin Sikder, Ridwan Bin Rashid, AKM Nawshad Hossian, Mohammad A Rashid
      Abstract: The study was designed to evaluate the preliminary biological activities of crude methanol extracts of the leaf of Justicia gendarussa, Sansevieria trifasciata and Hydnocarpus kurzii and their organic soluble partitionates. The polyphenol content was determined spectrophotometrically and expressed as gallic acid equivalents. The total phenolic content was found to vary for different test samples ranging from 1.45 ± 0.25 mg to 40.73 ± 0.22 mg of GAE/ gm of dried extract. The antioxidant potential was evaluated by DPPH free radical scavenging assay using butylated hydroxytolune (BHT) and ascorbic acid as standards. In the assay, the CSF of H. kurzii and the PESF of J. gendarussa revealed the highest free radical scavenging activity with IC50 values 3.25 ± 0.05 μg/ml and 24.68 ± 0.26 μg/ml, respectively. The brine shrimp lethality bioassay was utilized to evaluate the cytotoxicity. The chloroform soluble fraction (CSF) and methanol extract (ME) of J. gendarussa exhibited strong cytotoxicity with LC50 values of 0.002 μg/ml and 0.06 μg/ml, respectively. The membrane stabilizing activity was assessed by evaluating hemolysis of RBC in hypotonic solution and was compared with acetyl salicylic acid. On the other hand, the chloroform soluble fraction of J. gendarussa and aqueous soluble materials of S. trifasciata produced 75.60% and 75.0% inhibition of hemolysis of RBC, respectively as compared to 77.9% inhibited by acetyl salicylic acid (0.10 mg/ml).
      DOI : http://dx.doi.org/10.3329/bpj.v17i2.22331 Bangladesh Pharmaceutical Journal 17(2): 147-150, 2014
      PubDate: 2015-02-21
      Issue No: Vol. 17 (2015)
       
  • In vitro Thrombolytic and Membrane Stabilizing Studies of Brassica rapa
           subsp. chinensis (L.) Hanelt
    • Authors: Nushrat Jahan, SM Ashikur Rahman, Mohammad S Rahman, Mohammad A Rashid
      Abstract: Brassica rapa subsp. chinensis (L.) Hanelt is a popular herb in Bangladesh. In the present studies, the plant has been assessed to evaluate its in vitro thrombolytic and membrane stabilizing properties. Initially, the plant was collected, processed and extracted with methanol and the concentrated crude methanol extract was fractionated into petroleum ether, carbon tetrachloride, chloroform and aqueous soluble materials. All extractives, including the parent extract were subjected to thrombolytic and membrane stabilizing bioassays. In case of thrombolytic study, the carbon tetrachloride soluble fraction exhibited highest clot lysis. Here, streptokinase and distilled water were used as positive and negative control, respectively. However, in the assay for membrane stabilizing activity, the crude methanol extract along with other extractives were capable to inhibit hemolysis of erythrocyte membrane in hypotonic solution- and heat- induced conditions, which indicated anti-inflammatory property of the samples. Acetyl salicylic acid was used as standard drug in this assay. This represents the first report of thrombolytic and membrane stabilizing activities of B. rapa subsp. chinensis.
      DOI : http://dx.doi.org/10.3329/bpj.v17i2.22336 Bangladesh Pharmaceutical Journal 17(2): 172-176, 2014
      PubDate: 2015-02-21
      Issue No: Vol. 17 (2015)
       
  • Pharmacological Activities of Senna obtusifolia Linn.: A Medicinal Plant
           of Bangladesh
    • Authors: Md Anisuzzaman, Md Qamrul Ahsan, Md Ruhul Kuddus, Mohammad Abdur Rashid
      Abstract: The crude methanol extract of seed of Senna obtusifolia Linn. has been investigated for anxiolytic, antiatherothrombosis, membrane stabilizing and alpha-amylase inhibitory activities. The anxiolytic activity was examined in mice by using the hole cross and open field test (OFT). The anti-atherothrombosis activity was evaluated and compared with that of standard streptokinase. The membrane stabilizing activity was tested by using hypotonic solution- and heat-induced hemolysis of human erythrocyte. The plant extract was also assessed for anti-diabetic activity through in vitro α-amylase inhibitory potential. The α-amylase inhibitory activity of S. obtusifolia was measured using the starch-iodine method. The crude extract of S. obtusifolia showed moderate anxiolytic activity. In the in-vitro anti-atherothrombosis test, the extract exhibited mild activity as compared to the standard, streptokinase (81.53%). In membrane stabilizing activity test, the plant extract at 1.0 mg/ml inhibited the heat-induced hemolysis of RBCs by 56.37% whereas the standard acetyl salicylic acid (ASA) demonstrated 71.36% inhibition of hemolysis. Our results revealed that the extract produced dose-dependent prevention of digestion of carbohydrates by inhibiting α-amylase. These findings demonstrated that S. obtusifolia may be a good candidate for further analysis because of its effective pharmacological properties.
      DOI : http://dx.doi.org/10.3329/bpj.v17i2.22338 Bangladesh Pharmaceutical Journal 17(2): 182-186, 2014
      PubDate: 2015-02-21
      Issue No: Vol. 17 (2015)
       
  • Antidiabetic Activity of Lupeol and Lupeol Esters in Streptozotocin-
           Induced Diabetic Rats
    • Authors: Vijai Lakshmi, Abbas Ali Mahdi, Mohammad Kaleem Ahmad, Santosh Kumar Agarwal, Arvind Kumar Srivastava
      Abstract: Currently, natural products have been shown to present interesting biological and pharmacological activities and are also used as chemotherapeutic agents. Plants have been used in treating cancer, cardiovascular disorders, tuberculosis and many other diseases. Therefore, the current study was designed to evaluate the antidiabetic potential of lupeol and its semisynthetic derivatives to get a new and potent antidiabetic agent. The ethanol extract of Crataeva nurvala, its hexane and chloroform soluble fractions and lupeol isolated from the extractives were evaluated.. Lupeol derivatives were prepared through a one-step reaction with acid chlorides, long chain fatty acids and aromatic moieties. A series of ester derivatives of lupeol were assayed for antidiabetic activity in (STZsucrose model rats. Few derivatives of lupeol showed more potent activity as compared to the basic molecule, lupeol. The results of the present study clearly indicated that the ethanol extract, fractions and lupeol isolated from C. nurvala and synthetic lupeol analogs possess significant antidiabetic activity. The models used for studying theantidiabetic activities have already been validated. In our studies, it was found that the ester derivatives of lupeol posses better antidiabetic potential when compared to lupeol. It is thus concluded that lupeol skeleton deserves further investigation for the development of more potent and non-toxic new antidiabetic agents for therapeutic applications.
      DOI : http://dx.doi.org/10.3329/bpj.v17i2.22330 Bangladesh Pharmaceutical Journal 17(2): 138-146, 2014
      PubDate: 2015-02-21
      Issue No: Vol. 17 (2015)
       
  • In vitro Insecticidal and Time-Kill Profile of Ethyl Acetate Extract of
           Marine Streptomyces sp. Isolated from Sundarbans, Bangladesh
    • Authors: Md Anwarul Haque, Ashish Kumar Sarker, Mohammad Sayful Islam, Md Ajijur Rahman, Md Akter Uzzaman Chouduri, Md Anwar Ul Islam
      Abstract: The marine soil and sediment samples were collected from different locations of mangrove forest Sundarbans, Bangladesh the largest tidal halophytic mangrove forest in the world. A total of twenty nine Actinomycete strains (AIAH-1 to AIAH-29) were isolated by serial dilution method using isolation media. Among twenty nine strains, AIAH-10 was selected for further study due to its potent antibacterial activity against a wide range of pathogenic bacterial strains. On the basis of morphological, cultural and biochemical studies, the strain AIAH-10 was assigned to Streptomyces sp. The present study was designed to investigate the in vitro insecticidal and time-kill profile of ethyl acetate extracts of marine Streptomyces sp. A dose dependent mortality was observed against the larvae of Sitophilus oryzae. The larval mortality was recorded as 100% in the concentration of 80 mg/ml and higher concentrations, LC50 was found as 11.48 mg/ml. The minimum inhibitory concentration was recorded as 8 to 32 mg/ml against six different pathogenic bacterial strains. Average Log10 reductions in viable cell counts for the extracts ranged from 1.91 Log10 and 2.86 Log10 cfu/mL after 3 h interaction and 2.10 Log10 and 2.93 Log10 after 6 h interaction at MIC, 2 × MIC, 3 × MIC and 4 × MIC concentrations. This investigation reveals that the Streptomyces species isolated from Sundarbans, Bangladesh may be interesting source for the isolation of potent bioactive compounds.
      DOI : http://dx.doi.org/10.3329/bpj.v17i2.22332 Bangladesh Pharmaceutical Journal 17(2): 151-156, 2014
      PubDate: 2015-02-21
      Issue No: Vol. 17 (2015)
       
  • Equilibrium and Kinetic Studies of Adsorption of Aqueous Crystal Violet by
           Peanut Shells
    • Authors: Hosne Ara Begum, Md Ariful Islam, Tanvir Muslim
      Abstract: In the present study, the ability of a non-conventional biosorbent, peanut shells (PnS) for the removal of crystal violet (CV), a cationic dye, from aqueous solution was evaluated. The surface zero point charge (pHzpc) of peanut shells was estimated and found to be 6.27. Batch adsorption experiments were performed and system variables were investigated including contact time, initial dye concentration, temperature and pH of the solution. The estimated equilibrium time was found to be 4 hours. The adsorption of CV on PnS was found to increase with the increment of initial concentration of CV solution and pH of the medium. The equilibrium adsorption data were fitted to the Langmuir and Freunlich isotherms. The best result was achieved with Langmuir isotherm model. The adsorption rates were found to be consistent with a pseudo-second-order model. The result showed that the amount of CV adsorbed decreased with the increase of temperature. It suggested that the adsorption occurred due to physical interaction and it was favorable at lower temperature. The value of activation energy Ea (11.27 kJ mol−1) revealed that adsorption process was spontaneous and exothermic in nature. The adsorption of crystal violet by peanut shell suggests that this adsorbent may be evaluated for removal of other dyes produced and/or used in pharmaceutical process industries.
      DOI : http://dx.doi.org/10.3329/bpj.v17i2.22335 Bangladesh Pharmaceutical Journal 17(2): 163-171, 2014
      PubDate: 2015-02-21
      Issue No: Vol. 17 (2015)
       
  • Pharmacological Activities of Grevillea robusta, a Medicinal Plant of
           Bangladesh
    • Authors: Md Sharif Ullah, Md Al Amin Sikder, Tasnuva Sharmin, Mohammad A Rashid
      Abstract: The objective of this study was to evaluate the crude methanol extract of leaf of Grevillea robusta as well as its hexane, carbon tetrachloride, chloroform and aqueous soluble partitionates for cytotoxic, thrombolytic, membrane stabilizing and antimicrobial activities. In the brine shrimp lethality bioassay, the crude methanolic extract of G. robusta leaf revealed the highest cytotoxic activity with LC50 values as 1.50 ± 0.45 μg/ml as compared to 0.45 μg/ml for vincristine sulphate. Among the extractives of G. robusta, the carbon tetrachloride soluble fraction showed 69.95±0.11% clot lysis as compared to 70.77% clot lysis by standard streptokinase. At concentration of 1.0 mg/ml, the chloroform soluble fraction inhibited 40.31 ± 0.59% and 62.93 ± 0.73% of haemolysis of RBC induced by heat and hypotonic solution as compared to 42.12% and 71.90% by acetyl salicylic acid, respectively. The test samples also showed antimicrobial activity with zone of inhibition ranging from 7.0 to 17.0 mm in diameter. The chloroform soluble partitionate demonstrated the highest zone of inhibition (17.0 mm) against Salmonella Typhi.
      DOI : http://dx.doi.org/10.3329/bpj.v17i2.22329 Bangladesh Pharmaceutical Journal 17(2): 135-137, 2014
      PubDate: 2015-02-21
      Issue No: Vol. 17 (2015)
       
  • Preliminary Free Radical Scavenging, Brine Shrimp Lethality, Antimicrobial
           and Thrombolytic Activities of Aganosma dichotoma (Roth) K. Schum.
    • Authors: Sanjoy Chandra Dey, Mohammd Firoz Khan, Mohammad S Rahman, Mohammad A Rashid
      Abstract: Bangladesh is a good repository of natural products. Numerous plants are available to facilitate the traditional treatments. Proper scientific evaluations are essential to explore the plant derived drugs. With this view, the crude methanol extract of leaves of Aganosma dichotoma (Roth) K. Schum. and its Kupchan fractions were screened for free radical scavenging, brine shrimp lethality, antimicrobial and thrombolytic activities. Among all extractives, the chloroform soluble fraction demonstrated the highest free radical scavenging activity with IC50 value 18.21 μg/ml. Moreover, the chloroform soluble fraction showed significant brine shrimp lethality having LC50 value of 3.98 μg/ml. On the other hand, the petroleum ether, carbon tetrachloride and chloroform soluble materials revealed mild to moderate antimicrobial activity with the zone of inhibition ranging from 7 to 14 mm. In the thrombolytic assay, the carbon tetrachloride soluble partitionate showed the highest clot lysis (30.48%). This is the first report of the comprehensive investigations of different extractives of A. dichotoma for the abovementioned bioassays.
      DOI : http://dx.doi.org/10.3329/bpj.v17i2.22337 Bangladesh Pharmaceutical Journal 17(2): 177-181, 2014
      PubDate: 2015-02-21
      Issue No: Vol. 17 (2015)
       
  • Comparative Evaluation of Solanum tuberosum L. and Manihot esculenta
           
    • Authors: Md Mahadi Hasan, Md Sohel Rana, Nizam Uddin, Kazi Jamiur Rahman, Sanchita Sharmin Chowdhury
      Abstract: This investigation was aimed at comparing the newly developed starches from two grains; Potato (Solanum tuberosum) and Cassava (Manihot esculenta). The presence of starch in as these grains vary and thus their use as pharmaceutical excipients will depend on the degree of their starch functionality. The organoleptic and physicochemical characteristics such as viscosity, swelling capacity, moisture sorption capacity, pH, flow rate, Carr’s index, and Hausner’s ratio were evaluated. The powders passed the identification and solubility tests as required by the British Pharmacopoeia. Cassava starch showed the least Carr’s index, Hausner’s ratio and moisture sorption capacity but displayed more angle of repose and true density than the potato starch. In contrast, potato starch showed the highest hydration and swelling-capacity. That is why, potato starch could be a better tablet disintegrant compared to cassava starch. The results obtained demonstrated that between the two starches in relation to their flow ability, cassava starch possesses the best flow property. Infrared (IR) spectra of potato and cassava starch with the drug sample (Etoricoxib) were seen to retain the individual peak of potato and cassava starch and the IR spectra showed that there was no interaction of starch with the drug.
      DOI : http://dx.doi.org/10.3329/bpj.v17i2.22328 Bangladesh Pharmaceutical Journal 17(2): 128-134, 2014
      PubDate: 2015-02-21
      Issue No: Vol. 17 (2015)
       
  • DSC and HPLC Studies of Some Common Antidiabetic and Antihypertensive
           Drugs
    • Authors: Md Anisur Rahman, Md Abdus Salam, Md Zakir Sultan, Khohinur Hossain, Asma Rahman, Mohammad A Rashid
      Abstract: Now-a-days, a significant percentage of our population suffers from diabetes, hypertension and various inflammatory conditions. In such cases antihypertensive, antidiabetic and anti inflammatory drugs are prescribed concomitantly. Therefore, there is a possibility to have drug-drug interactions which may cause various complications to the patients or may be beneficial too. So study of drug-drug interaction is very important. To attain this objective, equimolar homogeneous mixture of naproxen, losartan potassium and pioglitazone HCl (mixture-1) and mixture of lercanidipine, captropril, naproxen and glimepiride (mixture-2) were studied by DSC (differential scanning calorimetry) and HPLC. DSC studies revealed that there was no interaction among naproxen, losartan potassium and pioglitazone HCl but same interaction was observed among lercanidipine, captropril, naproxen and glimepiride. The results obtained from DSC were further verified by HPLC. However, further studies are needed to make any conclusive remarks at this point. In future, the drug-drug interactions involving these molecules will be quantitatively evaluated for more precise predictions of in vivo drug-drug interactions.
      DOI : http://dx.doi.org/10.3329/bpj.v17i2.22326 Bangladesh Pharmaceutical Journal 17(2): 123-127, 2014
      PubDate: 2015-02-21
      Issue No: Vol. 17 (2015)
       
  • Synthesis, Characterization and Antibacterial Studies of the Mixed Ligand
           Complexes of Pd(II) and Pt(II) Ions with Phthalic Acid and Heterocyclic
           Amines
    • Authors: Md Belayet Hossain, Md Abdus Salam, Abdur Rashed, MA Yousuf
      Abstract: Mixed ligand complexes of Pd(II) and Pt(II) ions with phthalic acid and heterocyclic amines were synthesized and characterized. The general formula of the complexes is [MLL/]; where, M = Pd(II)(1-2), Pt(II)(3); L = phthalate, C8H4O4, L/ = pyridine, C5H5N(1); 2-aminopyridine, C5H6N2(2) and 4-picoline, C6H7N(3). The complexes were synthesized in the solid form and characterized by elemental analysis, electrical conductivity, magnetic measurements, and spectroscopic studies. Spectral analyses and magnetic measurements revealed the coordination of metal ion with ligands and geometry of the complexes. Anti-bacterial activity of the complexes against seven pathogenic bacteria (three gram positive and four gram negative) was assessed by the disc diffusion method. Complexes [Pd(Ph)(2-apy)] and [Pt(Ph)(4-pico)2] showed the highest anti-bacterial activity (when, Ph = bidentate phthalate, 2-apy = 2-aminopyridine and 4-pico = 4-picoline).
      DOI : http://dx.doi.org/10.3329/bpj.v17i2.22333 Bangladesh Pharmaceutical Journal 17(2): 157-162, 2014
      PubDate: 2015-02-21
      Issue No: Vol. 17 (2015)
       
  • Medical News 17(2)
    • Authors: The Editor
      Abstract: not available
      DOI : http://dx.doi.org/10.3329/bpj.v17i2.22344 Bangladesh Pharmaceutical Journal 17(2): 217-225, 2014
      PubDate: 2015-02-21
      Issue No: Vol. 17 (2015)
       
  • In vitro Thrombolytic Activity of Albizia lebbeck Benth.
    • Authors: Saiful Islam Sohaily, Md Mohidur Rahman, Mohammad Firoz Khan, Mohammad A Rashid
      Abstract: not available
      DOI : http://dx.doi.org/10.3329/bpj.v17i2.22343 Bangladesh Pharmaceutical Journal 17(2): 215-216, 2014
      PubDate: 2015-02-21
      Issue No: Vol. 17 (2015)
       
  • In vitro Cytotoxic, Membrane Stabilizing and Thrombolytic Activities of
           Polygonum glabrum Willd
    • Authors: Mohammad Firoz Khan, Sikder Nahidul Islam Rabbi, Fahima Aktar, Md Hassan Kawsar
      Abstract: The crude methanol extract of leaves of Polygonum glabrum Willd and its Kupchan fractions were screened for cytotoxic, membrane stabilizing and thrombolytic activities. Among all fractions, the crude methanol extract showed significant cytotoxic activity having LC50 value 0.74 ± 0.045 μg/ml. Moreover, in hypotonic solution- and heat- induced conditions, the crude methanol extract inhibited hemolysis of human erythrocyte by 79.21 ± 0.44% and 84.87±0.23%, respectively as compared to 71.9 ± 0.73% and 42.12 ± 0.37% demonstrated by the standard acetyl salicylic acid. On the other hand, in thrombolytic activity assay the methanol extract demonstrated highest clot lysis value of 35.17 ± 0.42%.
      DOI : http://dx.doi.org/10.3329/bpj.v17i2.22341 Bangladesh Pharmaceutical Journal 17(2): 202-204, 2014
      PubDate: 2015-02-21
      Issue No: Vol. 17 (2015)
       
  • Ethnomedicinal Survey of Plants in the Southern District Noakhali,
           Bangladesh
    • Authors: Rajesh Bhowmik, Monika Rani Saha, Md Ajijur Rahman, Md Anwar Ul Islam
      Abstract: Many modern medicines used today were discovered by extracting active chemicals from plants used in traditional medicine. To identify and locate any new and potential therapeutic aaplications of commonly used medicinal plants by the folk medicinal practitioners of Noakhali, Bangladesh, we conducted a survery with a semi-structured questionnaire using the guided field-walk method. Detailed information was obtained on 143 plants belonging to 62 families. Leaves were mostly used (52%) followed by roots (30.55%) and whole plants (18.74%) along with fruits, barks, seeds, stems and flowers. Gastrointestinal disorders were the most common diseases treated followed by respiratory tract infections, weakness, fever, diabetes, skin disorders, sexually transmitted diseases, hepatic disorders, pain and rheumatism. Some plants were also used for the treatment of cancer, hypertension, nerve disorders, helmenthiasis, urinary tract infections, tuberculosis, leucorrhea, edema and chicken pox. The findings of this study may help the scientists to get a comprehensive view of the folk medicinal practices in Bangladesh and can use the results to identify medicinal plants of therapeutic interests
      DOI : http://dx.doi.org/10.3329/bpj.v17i2.22342 Bangladesh Pharmaceutical Journal 17(2): 205-214, 2014
      PubDate: 2015-02-21
      Issue No: Vol. 17 (2015)
       
  • Synthesis of Some Chitosan Derivatives and Their Iron (II) Adsorption
           Behavior- a Class of Pharmaceutically Important Biosorbents
    • Authors: Tanvir Muslim, Muhammad Tanzirul Alam, Hosne Ara Begum, Syed Samsul Alam
      Abstract: In the present study, chitin was isolated from the shells of freshwater crab (Sartoriana spinigera), available in Bangladesh. The isolated chitin was converted into chtiosan by deacetylation reaction. The chtiosan was characterized by FT-IR and 1H-NMR spectral analyses. The prepared chitosan was reacted with glutaradehyde, vanillin and salicylaldehyde to synthesize chitosan Schiff bases- vanillin-chitosan, salicylaldehyde-chitosan and glutaradehyde-chitosan. Iron (II) adsorption behavior of these derivatives was studied under varying experimental conditions such as contact time and initial concentration of iron (II) solution. The equilibrium adsorption data were fitted to Freundlich and Langmuir adsorption isotherm models and the model parameters were evaluated. Both the models represented the experimental data satisfactorily. Maximum adsorption capacity for iron (II) ions on chitosan, vanillin-chitosan, salicylaldehyde-chitosan and glutaradehyde-chitosan was evaluated and found be to 68.03, 35.59, 7.50 and 4.78 mg/g, respectively. The uses of chitosan derivatives as environment friendly biosorbents in pharmaceutical and API industries have been hightlighted.
      DOI : http://dx.doi.org/10.3329/bpj.v17i2.22340 Bangladesh Pharmaceutical Journal 17(2): 193-201, 2014
      PubDate: 2015-02-21
      Issue No: Vol. 17 (2015)
       
  • Practice of Hospital Pharmacy in Bangladesh: Current Perspective
    • Authors: Tripti Rani Paul, Md Ajijur Rahman, Mohitosh Biswas, Mamunur Rashid, Md Anwar Ul Islam
      Abstract: Although hospital pharmacists are recognized for its importance as health care provider in many developed countries, in most developing countries it is still underutilized. The aim of the present study was to summarize the current scenario of pharmacy practices in four hospitals of Bangladesh and to identify the pharmacist’s rolesin these seftap. The study was conducted through convenient sampling method using a well-designed 14-item questionnaire to collect the opinions from the respondents. The results showed that hospital pharmacy service, as a unique department of hospital, existed in 50% of the studied hospitals where activities were done by graduate pharmacists and they were also involved in different departments to provide clinical services to the patients. The rest 50% of the studied hospitals had no hospital pharmacy service. Only a retail drug store inside the hospital was present and there was no diploma or graduate or any pharmacy technician for providing patient care. This study concludes that hospital pharmacy practice is just started in some private modern hospitals in Bangladesh which is inaccessible for the majority of peoples due to high patients cost of these hospitals.
      DOI : http://dx.doi.org/10.3329/bpj.v17i2.22339 Bangladesh Pharmaceutical Journal 17(2): 187-192, 2014
      PubDate: 2015-02-21
      Issue No: Vol. 17 (2015)
       
 
 
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